Search of human proteins with 4503303

Search of human proteins with 4503303

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503303 defensin, alpha 4 preproprotein [Homo sapiens]
         (97 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503303 defensin, alpha 4 preproprotein [Homo sapiens]             197   2e-51
gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]              91   2e-19
gi|10337585 defensin, alpha 5 preproprotein [Homo sapiens]             84   2e-17
gi|4758146 defensin, alpha 1 preproprotein [Homo sapiens]              84   3e-17
gi|124248516 alpha-defensin 1 [Homo sapiens]                           84   3e-17
gi|4885179 defensin, alpha 3 preproprotein [Homo sapiens]              82   7e-17
gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]        28   1.2  
gi|38327632 discoidin domain receptor family, member 1 isoform b...    27   3.5  
gi|83977452 discoidin domain receptor family, member 1 isoform c...    27   3.5  
gi|83977450 discoidin domain receptor family, member 1 isoform a...    27   3.5  
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]                  27   3.5  
gi|26892293 CD302 molecule [Homo sapiens]                              26   6.0  
gi|95089461 discs large homolog 5 [Homo sapiens]                       26   6.0  

>gi|4503303 defensin, alpha 4 preproprotein [Homo sapiens]
          Length = 97

 Score =  197 bits (500), Expect = 2e-51
 Identities = 97/97 (100%), Positives = 97/97 (100%)

Query: 1  MRIIALLAAILLVALQVRAGPLQARGDEAPGQEQRGPEDQDISISFAWDKSSALQVSGST 60
          MRIIALLAAILLVALQVRAGPLQARGDEAPGQEQRGPEDQDISISFAWDKSSALQVSGST
Sbjct: 1  MRIIALLAAILLVALQVRAGPLQARGDEAPGQEQRGPEDQDISISFAWDKSSALQVSGST 60

Query: 61 RGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRVD 97
          RGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRVD
Sbjct: 61 RGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRVD 97


>gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]
          Length = 100

 Score = 90.9 bits (224), Expect = 2e-19
 Identities = 48/100 (48%), Positives = 60/100 (60%), Gaps = 8/100 (8%)

Query: 1  MRIIALLAAILLVALQVRAGPLQARGD-------EAPGQEQRGPEDQDISISFAWDKSSA 53
          MR + +L A+LLVALQ +A PLQA  D       EA  QEQRG  DQD ++SFA D SS+
Sbjct: 1  MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS 60

Query: 54 LQVSGSTRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCC 93
          L+  GSTR   C CR   C  TE   G C + G++  +CC
Sbjct: 61 LRALGSTRAFTCHCRR-SCYSTEYSYGTCTVMGINHRFCC 99


>gi|10337585 defensin, alpha 5 preproprotein [Homo sapiens]
          Length = 94

 Score = 84.0 bits (206), Expect = 2e-17
 Identities = 47/93 (50%), Positives = 57/93 (61%)

Query: 1  MRIIALLAAILLVALQVRAGPLQARGDEAPGQEQRGPEDQDISISFAWDKSSALQVSGST 60
          MR IA+LAAILLVALQ +A  LQ R DEA  Q+Q G ++QD++ISFA +  SAL+ SGS 
Sbjct: 1  MRTIAILAAILLVALQAQAESLQERADEATTQKQSGEDNQDLAISFAGNGLSALRTSGSQ 60

Query: 61 RGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCC 93
              C CR   C   E   G C I G  +  CC
Sbjct: 61 ARATCYCRTGRCATRESLSGVCEISGRLYRLCC 93


>gi|4758146 defensin, alpha 1 preproprotein [Homo sapiens]
          Length = 94

 Score = 83.6 bits (205), Expect = 3e-17
 Identities = 44/94 (46%), Positives = 58/94 (61%), Gaps = 1/94 (1%)

Query: 1  MRIIALLAAILLVALQVRAGPLQARGDE-APGQEQRGPEDQDISISFAWDKSSALQVSGS 59
          MR +A+LAAILLVALQ +A PLQAR DE A   EQ   +  ++ +S AWD+S A +  GS
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60

Query: 60 TRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCC 93
           + M C CR+  C   E R G C+  G  + +CC
Sbjct: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|124248516 alpha-defensin 1 [Homo sapiens]
          Length = 94

 Score = 83.6 bits (205), Expect = 3e-17
 Identities = 44/94 (46%), Positives = 58/94 (61%), Gaps = 1/94 (1%)

Query: 1  MRIIALLAAILLVALQVRAGPLQARGDE-APGQEQRGPEDQDISISFAWDKSSALQVSGS 59
          MR +A+LAAILLVALQ +A PLQAR DE A   EQ   +  ++ +S AWD+S A +  GS
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60

Query: 60 TRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCC 93
           + M C CR+  C   E R G C+  G  + +CC
Sbjct: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|4885179 defensin, alpha 3 preproprotein [Homo sapiens]
          Length = 94

 Score = 82.4 bits (202), Expect = 7e-17
 Identities = 44/94 (46%), Positives = 58/94 (61%), Gaps = 1/94 (1%)

Query: 1  MRIIALLAAILLVALQVRAGPLQARGDE-APGQEQRGPEDQDISISFAWDKSSALQVSGS 59
          MR +A+LAAILLVALQ +A PLQAR DE A   EQ   +  ++ +S AWD+S A +  GS
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60

Query: 60 TRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCC 93
           + M C CR+  C   E R G C+  G  + +CC
Sbjct: 61 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]
          Length = 882

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 30/98 (30%), Positives = 36/98 (36%), Gaps = 19/98 (19%)

Query: 6  LLAAILLVALQVRAGPLQARGDE-APGQEQR---------GPEDQDISISFAWDKSSALQ 55
          LL A  L A +  A   Q+ GDE  PG+ +R           ED D S      + S   
Sbjct: 2  LLGASWLCASKAAAAAAQSEGDEDRPGERRRRRAAATAAGAGEDMDESSLLDLLECSVCL 61

Query: 56 VSGSTRGMVCSCRLVFCRRT---------ELRVGNCLI 84
              T   V  C+  FCRR          ELR   C I
Sbjct: 62 ERLDTTAKVLPCQHTFCRRCLESIVCSRHELRCPECRI 99


>gi|38327632 discoidin domain receptor family, member 1 isoform b
          [Homo sapiens]
          Length = 876

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 11/77 (14%)

Query: 11 LLVALQVRAGPLQARGDEAP-------GQEQRGPEDQDISISFAWDKSSALQ----VSGS 59
          LL+ L V +G    +G   P       G + R   D DIS S +W  S+A +     S  
Sbjct: 9  LLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSD 68

Query: 60 TRGMVCSCRLVFCRRTE 76
            G  C    VF +  E
Sbjct: 69 GDGAWCPAGSVFPKEEE 85


>gi|83977452 discoidin domain receptor family, member 1 isoform c
          [Homo sapiens]
          Length = 919

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 11/77 (14%)

Query: 11 LLVALQVRAGPLQARGDEAP-------GQEQRGPEDQDISISFAWDKSSALQ----VSGS 59
          LL+ L V +G    +G   P       G + R   D DIS S +W  S+A +     S  
Sbjct: 9  LLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSD 68

Query: 60 TRGMVCSCRLVFCRRTE 76
            G  C    VF +  E
Sbjct: 69 GDGAWCPAGSVFPKEEE 85


>gi|83977450 discoidin domain receptor family, member 1 isoform a
          [Homo sapiens]
          Length = 913

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 11/77 (14%)

Query: 11 LLVALQVRAGPLQARGDEAP-------GQEQRGPEDQDISISFAWDKSSALQ----VSGS 59
          LL+ L V +G    +G   P       G + R   D DIS S +W  S+A +     S  
Sbjct: 9  LLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSD 68

Query: 60 TRGMVCSCRLVFCRRTE 76
            G  C    VF +  E
Sbjct: 69 GDGAWCPAGSVFPKEEE 85


>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
          Length = 1726

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 11/19 (57%), Positives = 13/19 (68%)

Query: 20  GPLQARGDEAPGQEQRGPE 38
           G  +  GDEA  +EQRGPE
Sbjct: 496 GDEEGEGDEAEDEEQRGPE 514


>gi|26892293 CD302 molecule [Homo sapiens]
          Length = 232

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 12/77 (15%)

Query: 32  QEQRGPEDQDISI-------SFAWDKSSALQVSGST-----RGMVCSCRLVFCRRTELRV 79
           ++ +GP+D  + +       SF W  +S +     T       +V +C  +  +  E + 
Sbjct: 81  KQWKGPDDILLGMFYDTDDASFKWFDNSNMTFDKWTDQDDDEDLVDTCAFLHIKTGEWKK 140

Query: 80  GNCLIGGVSFTYCCTRV 96
           GNC +  V  T C T +
Sbjct: 141 GNCEVSSVEGTLCKTAI 157


>gi|95089461 discs large homolog 5 [Homo sapiens]
          Length = 1919

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 14/48 (29%), Positives = 25/48 (52%)

Query: 39   DQDISISFAWDKSSALQVSGSTRGMVCSCRLVFCRRTELRVGNCLIGG 86
            +QD   S    K S+ +++G         R+VF ++++L +G  L GG
Sbjct: 1472 EQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGG 1519


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.138    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,545,593
Number of Sequences: 37866
Number of extensions: 129918
Number of successful extensions: 543
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 530
Number of HSP's gapped (non-prelim): 13
length of query: 97
length of database: 18,247,518
effective HSP length: 68
effective length of query: 29
effective length of database: 15,672,630
effective search space: 454506270
effective search space used: 454506270
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.