Guide to the Human Genome
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Name: DEFA4 Sequence: fasta or formatted (97aa) NCBI GI: 4503303
Description:

defensin, alpha 4 preproprotein

Referenced in:

Neutrophils, Eosinophils, and Basophils
Additional Host Defense Functions

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.3          9           2
 C cysteine            6.2          6           2
 D aspartate           5.2          5           1
 E glutamate           4.1          4           1
 F phenylalanine       3.1          3           1
 G glycine             9.3          9           2
 H histidine           0.0          0           0
 I isoleucine          6.2          6           2
 K lysine              1.0          1           1
 L leucine            10.3         10           2
 M methionine          2.1          2           1
 N asparagine          1.0          1           1
 P proline             3.1          3           1
 Q glutamine           6.2          6           1
 R arginine           10.3         10           2
 S serine              8.2          8           2
 T threonine           4.1          4           1
 V valine              8.2          8           1
 W tryptophan          1.0          1           1
 Y tyrosine            1.0          1           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   defensin, alpha 4 preproprotein 
DEFA6                 0.384   defensin, alpha 6 preproprotein 
DEFA5                 0.343   defensin, alpha 5 preproprotein 
DEFA1                 0.343   defensin, alpha 1 preproprotein 
LOC728358             0.343   alpha-defensin 1 
DEFA3                 0.331   defensin, alpha 3 preproprotein 
SH3RF3                0.017   SH3 domain containing ring finger 3 
DDR1                  0.012   discoidin domain receptor family, member 1 isoform b...
DDR1                  0.012   discoidin domain receptor family, member 1 isoform c...
DDR1                  0.012   discoidin domain receptor family, member 1 isoform a...
SUPT6H                0.012   suppressor of Ty 6 homolog 
CD302                 0.006   CD302 molecule 
DLG5                  0.006   discs large homolog 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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