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Search of human proteins with 4502381
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502381 BCL2-like 1 isoform 2 [Homo sapiens]
(170 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502381 BCL2-like 1 isoform 2 [Homo sapiens] 340 3e-94
gi|20336335 BCL2-like 1 isoform 1 [Homo sapiens] 251 2e-67
gi|72198346 B-cell lymphoma protein 2 beta isoform [Homo sapiens] 64 5e-11
gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens] 64 5e-11
gi|4757842 BCL2-like 2 protein [Homo sapiens] 59 2e-09
gi|13236549 major facilitator superfamily domain containing 11 [... 35 0.031
gi|119943096 dopamine receptor interacting protein [Homo sapiens] 30 1.3
gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C) ... 29 2.2
gi|122891864 zinc finger protein, subfamily 1A, 4 [Homo sapiens] 28 2.9
gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo sa... 28 5.0
gi|169214102 PREDICTED: similar to hCG92381 [Homo sapiens] 27 6.5
gi|169214479 PREDICTED: similar to hCG92381 [Homo sapiens] 27 6.5
gi|169213433 PREDICTED: hypothetical protein LOC646698 [Homo sap... 27 6.5
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 27 6.5
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 27 6.5
gi|33624873 spectrin repeat containing, nuclear envelope 2 isofo... 27 6.5
gi|18426913 drebrin 1 isoform b [Homo sapiens] 27 6.5
gi|18426915 drebrin 1 isoform a [Homo sapiens] 27 6.5
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 27 8.5
gi|33624861 spectrin repeat containing, nuclear envelope 2 isofo... 27 8.5
>gi|4502381 BCL2-like 1 isoform 2 [Homo sapiens]
Length = 170
Score = 340 bits (872), Expect = 3e-94
Identities = 170/170 (100%), Positives = 170/170 (100%)
Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA 60
MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA
Sbjct: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA 60
Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120
DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY
Sbjct: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120
Query: 121 QSFEQDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 170
QSFEQDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
Sbjct: 121 QSFEQDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 170
>gi|20336335 BCL2-like 1 isoform 1 [Homo sapiens]
Length = 233
Score = 251 bits (642), Expect = 2e-67
Identities = 125/125 (100%), Positives = 125/125 (100%)
Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA 60
MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA
Sbjct: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA 60
Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120
DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY
Sbjct: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120
Query: 121 QSFEQ 125
QSFEQ
Sbjct: 121 QSFEQ 125
Score = 93.2 bits (230), Expect = 1e-19
Identities = 45/45 (100%), Positives = 45/45 (100%)
Query: 126 DTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 170
DTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
Sbjct: 189 DTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 233
>gi|72198346 B-cell lymphoma protein 2 beta isoform [Homo sapiens]
Length = 205
Score = 64.3 bits (155), Expect = 5e-11
Identities = 46/126 (36%), Positives = 64/126 (50%), Gaps = 13/126 (10%)
Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLAD--- 61
NRE+V+ ++ YKLSQ+GY W DV AP G S+ G+ A
Sbjct: 11 NREIVMKYIHYKLSQRGYEWDA-GDVGA----APPGAAPAPGIFSSQPGHTPHPAASRDP 65
Query: 62 ----SPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPG 117
SP A +++ A +P V LR+AGD+F RYRR F++++SQLH+TP
Sbjct: 66 VARTSPLQTPAAPGAAAGPALSPVP-PVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPF 124
Query: 118 TAYQSF 123
TA F
Sbjct: 125 TARGRF 130
>gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens]
Length = 239
Score = 64.3 bits (155), Expect = 5e-11
Identities = 46/126 (36%), Positives = 64/126 (50%), Gaps = 13/126 (10%)
Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLAD--- 61
NRE+V+ ++ YKLSQ+GY W DV AP G S+ G+ A
Sbjct: 11 NREIVMKYIHYKLSQRGYEWDA-GDVGA----APPGAAPAPGIFSSQPGHTPHPAASRDP 65
Query: 62 ----SPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPG 117
SP A +++ A +P V LR+AGD+F RYRR F++++SQLH+TP
Sbjct: 66 VARTSPLQTPAAPGAAAGPALSPVP-PVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPF 124
Query: 118 TAYQSF 123
TA F
Sbjct: 125 TARGRF 130
>gi|4757842 BCL2-like 2 protein [Homo sapiens]
Length = 193
Score = 58.9 bits (141), Expect = 2e-09
Identities = 41/120 (34%), Positives = 50/120 (41%), Gaps = 49/120 (40%)
Query: 6 RELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAV 65
R LV DF+ YKL QKGY P + PA
Sbjct: 11 RALVADFVGYKLRQKGY---------------------------VCGAGP----GEGPAA 39
Query: 66 NGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQ 125
+ + QA+R AGDEFE R+RR FSDL +QLH+TPG+A Q F Q
Sbjct: 40 D------------------PLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQ 81
>gi|13236549 major facilitator superfamily domain containing 11
[Homo sapiens]
Length = 449
Score = 35.0 bits (79), Expect = 0.031
Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 3/122 (2%)
Query: 47 TPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFS 106
T ++ G + L P G S D +++ + + L +A D F+ ++ +
Sbjct: 177 TVISLVGTVLFFLIRKPDSENVLGEDESSDDQDMEVNESAQNNLTKAVDAFKKSFKLCVT 236
Query: 107 DLTSQLHITPGTAYQSFEQDTFVELYGNNAAAESRKGQERFNRWFLTGMTVA-GVVLLGS 165
L IT TAY E F +YG A ++ G E + L+G+ + G +L GS
Sbjct: 237 KEMLLLSIT--TAYTGLELTFFSGVYGTCIGATNKFGAEEKSLIGLSGIFIGIGEILGGS 294
Query: 166 LF 167
LF
Sbjct: 295 LF 296
>gi|119943096 dopamine receptor interacting protein [Homo sapiens]
Length = 702
Score = 29.6 bits (65), Expect = 1.3
Identities = 21/80 (26%), Positives = 33/80 (41%)
Query: 31 EENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQAL 90
+EN T + S + PSA N + + + P G G SS+ P +
Sbjct: 109 KENETGNQKDGNSFLSIPSACNCQGTPGIPEGPYSEGGNGSSSNFCHHCTSPALGEDELE 168
Query: 91 REAGDEFELRYRRAFSDLTS 110
E DE L++ FS ++S
Sbjct: 169 EEYDDEESLKFPSDFSRVSS 188
>gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C)
precursor [Homo sapiens]
Length = 539
Score = 28.9 bits (63), Expect = 2.2
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 40 GTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAR 78
G E ++ +A+ G +W ADSP + G T + S DA+
Sbjct: 84 GPEEVLQESAAVTGT-AWLEADSPGLGGVTAEAGSGDAQ 121
>gi|122891864 zinc finger protein, subfamily 1A, 4 [Homo sapiens]
Length = 585
Score = 28.5 bits (62), Expect = 2.9
Identities = 18/60 (30%), Positives = 27/60 (45%)
Query: 15 YKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSS 74
YK + G S+ Q S +EE++ +S A+ G P + D V + HSSS
Sbjct: 248 YKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQPGDEIRDLEMVPDSMLHSSS 307
>gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo
sapiens]
Length = 805
Score = 27.7 bits (60), Expect = 5.0
Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 9/64 (14%)
Query: 2 SQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLAD 61
S SNR LS +G D E+N E PE T S P ++G P+ L
Sbjct: 725 STSNRSSTRSLLSVSSGMEG-------DNEDN--EVPEVTRSRSPGPPQVDGTPTMSLER 775
Query: 62 SPAV 65
P V
Sbjct: 776 PPRV 779
>gi|169214102 PREDICTED: similar to hCG92381 [Homo sapiens]
Length = 497
Score = 27.3 bits (59), Expect = 6.5
Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 36 EAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMA 84
E P+G + + S G P + SP GA H + +A+E++P A
Sbjct: 306 EGPQGGATPVGN-SESPGKPEINSVYSPGPAGAVSHPNGQEAKELLPFA 353
>gi|169214479 PREDICTED: similar to hCG92381 [Homo sapiens]
Length = 497
Score = 27.3 bits (59), Expect = 6.5
Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 36 EAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMA 84
E P+G + + S G P + SP GA H + +A+E++P A
Sbjct: 306 EGPQGGATPVGN-SESPGKPEINSVYSPGPAGAVSHPNGQEAKELLPFA 353
>gi|169213433 PREDICTED: hypothetical protein LOC646698 [Homo
sapiens]
Length = 497
Score = 27.3 bits (59), Expect = 6.5
Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 36 EAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMA 84
E P+G + + S G P + SP GA H + +A+E++P A
Sbjct: 306 EGPQGGATPVGN-SESPGKPEINSVYSPGPAGAVSHPNGQEAKELLPFA 353
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 27.3 bits (59), Expect = 6.5
Identities = 14/46 (30%), Positives = 23/46 (50%)
Query: 10 VDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNP 55
VD ++ KG+S S+ E+ + E +E+EM S G+P
Sbjct: 686 VDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHP 731
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 27.3 bits (59), Expect = 6.5
Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 14 SYKLSQKGYSWSQFSDVE--ENRTEAPEGTESEMETPS--AINGNPSWHLADSPA 64
S++ ++G +S SDVE EN + T ++ S +I+ SWH+ DSP+
Sbjct: 6430 SHEEDEEGPYYSALSDVEIPENPEAYLKMTTKTLKASSGKSISDGHSWHVPDSPS 6484
Score = 26.9 bits (58), Expect = 8.5
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 38 PEGTESEMETPSAINGNPSWHLADSPAV----NGATGHSSSLDAREVIPMAAVKQALREA 93
P GT+ E P +NGNP + +GA + A+E+ +KQ L++
Sbjct: 6520 PPGTDGGKEGPRVLNGNPQQEDGGLAGITEQQSGAFDRWEMIQAQELHNKLKIKQNLQQL 6579
Query: 94 GDE 96
+
Sbjct: 6580 NSD 6582
>gi|33624873 spectrin repeat containing, nuclear envelope 2 isoform
4 [Homo sapiens]
Length = 556
Score = 27.3 bits (59), Expect = 6.5
Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 14 SYKLSQKGYSWSQFSDVE--ENRTEAPEGTESEMETPS--AINGNPSWHLADSPA 64
S++ ++G +S SDVE EN + T ++ S +I+ SWH+ DSP+
Sbjct: 64 SHEEDEEGPYYSALSDVEIPENPEAYLKMTTKTLKASSGKSISDGHSWHVPDSPS 118
Score = 26.9 bits (58), Expect = 8.5
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 38 PEGTESEMETPSAINGNPSWHLADSPAV----NGATGHSSSLDAREVIPMAAVKQALREA 93
P GT+ E P +NGNP + +GA + A+E+ +KQ L++
Sbjct: 154 PPGTDGGKEGPRVLNGNPQQEDGGLAGITEQQSGAFDRWEMIQAQELHNKLKIKQNLQQL 213
Query: 94 GDE 96
+
Sbjct: 214 NSD 216
>gi|18426913 drebrin 1 isoform b [Homo sapiens]
Length = 651
Score = 27.3 bits (59), Expect = 6.5
Identities = 28/123 (22%), Positives = 46/123 (37%), Gaps = 10/123 (8%)
Query: 25 SQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMA 84
S D EE R AP+ ME P P + + + ++ A V P
Sbjct: 383 SPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPAT 442
Query: 85 AVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQDTFVELY-GNNAAAESRKG 143
A + +A D E A +D T ++ P + ++L+ GN A + +G
Sbjct: 443 ADATEIHDAADTIET--DTATADTTVANNVPPAAT-------SLIDLWPGNGEGASTLQG 493
Query: 144 QER 146
+ R
Sbjct: 494 EPR 496
>gi|18426915 drebrin 1 isoform a [Homo sapiens]
Length = 649
Score = 27.3 bits (59), Expect = 6.5
Identities = 28/123 (22%), Positives = 46/123 (37%), Gaps = 10/123 (8%)
Query: 25 SQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMA 84
S D EE R AP+ ME P P + + + ++ A V P
Sbjct: 381 SPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPAT 440
Query: 85 AVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQDTFVELY-GNNAAAESRKG 143
A + +A D E A +D T ++ P + ++L+ GN A + +G
Sbjct: 441 ADATEIHDAADTIET--DTATADTTVANNVPPAAT-------SLIDLWPGNGEGASTLQG 491
Query: 144 QER 146
+ R
Sbjct: 492 EPR 494
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 26.9 bits (58), Expect = 8.5
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 38 PEGTESEMETPSAINGNPSWHLADSPAV----NGATGHSSSLDAREVIPMAAVKQALREA 93
P GT+ E P +NGNP + +GA + A+E+ +KQ L++
Sbjct: 6497 PPGTDGGKEGPRVLNGNPQQEDGGLAGITEQQSGAFDRWEMIQAQELHNKLKIKQNLQQL 6556
Query: 94 GDE 96
+
Sbjct: 6557 NSD 6559
>gi|33624861 spectrin repeat containing, nuclear envelope 2
isoform 2 [Homo sapiens]
Length = 429
Score = 26.9 bits (58), Expect = 8.5
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 38 PEGTESEMETPSAINGNPSWHLADSPAV----NGATGHSSSLDAREVIPMAAVKQALREA 93
P GT+ E P +NGNP + +GA + A+E+ +KQ L++
Sbjct: 28 PPGTDGGKEGPRVLNGNPQQEDGGLAGITEQQSGAFDRWEMIQAQELHNKLKIKQNLQQL 87
Query: 94 GDE 96
+
Sbjct: 88 NSD 90
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.127 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,079,768
Number of Sequences: 37866
Number of extensions: 249389
Number of successful extensions: 679
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 662
Number of HSP's gapped (non-prelim): 27
length of query: 170
length of database: 18,247,518
effective HSP length: 95
effective length of query: 75
effective length of database: 14,650,248
effective search space: 1098768600
effective search space used: 1098768600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.