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Search of human proteins with 4502247
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502247 armadillo repeat protein [Homo sapiens]
(962 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502247 armadillo repeat protein [Homo sapiens] 1933 0.0
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens] 781 0.0
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens] 765 0.0
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens] 765 0.0
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens] 765 0.0
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens] 765 0.0
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens] 754 0.0
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens] 728 0.0
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens] 728 0.0
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens] 712 0.0
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens] 712 0.0
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens] 712 0.0
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens] 712 0.0
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens] 701 0.0
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur... 488 e-138
gi|53829374 plakophilin 4 isoform a [Homo sapiens] 472 e-133
gi|53829376 plakophilin 4 isoform b [Homo sapiens] 471 e-132
gi|148664186 plakophilin 2 isoform 2a [Homo sapiens] 265 2e-70
gi|53729344 plakophilin 1 isoform 1a [Homo sapiens] 247 4e-65
gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo ... 247 4e-65
gi|148664226 plakophilin 2 isoform 2b [Homo sapiens] 243 5e-64
gi|6005830 plakophilin 3 [Homo sapiens] 243 8e-64
gi|53729346 plakophilin 1 isoform 1b [Homo sapiens] 234 2e-61
gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD... 54 5e-07
gi|148233338 catenin (cadherin-associated protein), beta 1, 88kD... 54 5e-07
gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa ... 54 5e-07
gi|189409124 armadillo repeat containing 3 [Homo sapiens] 54 5e-07
gi|31657114 armadillo repeat containing 4 [Homo sapiens] 54 9e-07
gi|4504811 junction plakoglobin [Homo sapiens] 51 6e-06
gi|12056468 junction plakoglobin [Homo sapiens] 51 6e-06
>gi|4502247 armadillo repeat protein [Homo sapiens]
Length = 962
Score = 1933 bits (5008), Expect = 0.0
Identities = 962/962 (100%), Positives = 962/962 (100%)
Query: 1 MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQQPGMVSGGMGSGQPL 60
MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQQPGMVSGGMGSGQPL
Sbjct: 1 MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQQPGMVSGGMGSGQPL 60
Query: 61 PMAWQQLVLQEQSPGSQASLATMPEAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRT 120
PMAWQQLVLQEQSPGSQASLATMPEAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRT
Sbjct: 61 PMAWQQLVLQEQSPGSQASLATMPEAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRT 120
Query: 121 ETKVTKTVKTVTTRTVRQVPVGPDGLPLLDGGPPLGPFADGALDRHFLLRGGGPVATLSR 180
ETKVTKTVKTVTTRTVRQVPVGPDGLPLLDGGPPLGPFADGALDRHFLLRGGGPVATLSR
Sbjct: 121 ETKVTKTVKTVTTRTVRQVPVGPDGLPLLDGGPPLGPFADGALDRHFLLRGGGPVATLSR 180
Query: 181 AYLSSGGGFPEGPEPRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGP 240
AYLSSGGGFPEGPEPRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGP
Sbjct: 181 AYLSSGGGFPEGPEPRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGP 240
Query: 241 EPGPPGGRSLPERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRA 300
EPGPPGGRSLPERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRA
Sbjct: 241 EPGPPGGRSLPERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRA 300
Query: 301 YEDTADDGGELADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPEL 360
YEDTADDGGELADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPEL
Sbjct: 301 YEDTADDGGELADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPEL 360
Query: 361 PEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRA 420
PEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRA
Sbjct: 361 PEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRA 420
Query: 421 CGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMV 480
CGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMV
Sbjct: 421 CGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMV 480
Query: 481 IIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRL 540
IIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRL
Sbjct: 481 IIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRL 540
Query: 541 RECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPL 600
RECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPL
Sbjct: 541 RECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPL 600
Query: 601 GSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQ 660
GSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQ
Sbjct: 601 GSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQ 660
Query: 661 PEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQS 720
PEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQS
Sbjct: 661 PEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQS 720
Query: 721 ETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVL 780
ETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVL
Sbjct: 721 ETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVL 780
Query: 781 NTIHEIVSDSLDNARSLLQARGVPALVALVASSQSVREAKAASHVLQTVWSYKELRGTLQ 840
NTIHEIVSDSLDNARSLLQARGVPALVALVASSQSVREAKAASHVLQTVWSYKELRGTLQ
Sbjct: 781 NTIHEIVSDSLDNARSLLQARGVPALVALVASSQSVREAKAASHVLQTVWSYKELRGTLQ 840
Query: 841 KDGWTKARFQSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALGPDG 900
KDGWTKARFQSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALGPDG
Sbjct: 841 KDGWTKARFQSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALGPDG 900
Query: 901 YSTVDRRERRPRGASSAGEASEKEPLKLDPSRKAPPPGPSRPAVRLVDAVGDAKPQPVDS 960
YSTVDRRERRPRGASSAGEASEKEPLKLDPSRKAPPPGPSRPAVRLVDAVGDAKPQPVDS
Sbjct: 901 YSTVDRRERRPRGASSAGEASEKEPLKLDPSRKAPPPGPSRPAVRLVDAVGDAKPQPVDS 960
Query: 961 WV 962
WV
Sbjct: 961 WV 962
>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
Length = 968
Score = 781 bits (2017), Expect = 0.0
Identities = 460/966 (47%), Positives = 610/966 (63%), Gaps = 75/966 (7%)
Query: 1 MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQ------QPGMVSGGM 54
M+D V S ASILASVKEQEA+FE+LTRALE+ERRHV+ QLER + P M +G +
Sbjct: 1 MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTL 60
Query: 55 ----------GSGQPLPMAWQQLVLQEQSPGSQASLATMP--EAPDVLEETVTVEEDPGT 102
G + L L S +T+P + P + ET T EEDP
Sbjct: 61 TRRHQNGRFVGDADLERQKFSDLKLNGPQDHSHLLYSTIPRMQEPGQIVETYT-EEDPEG 119
Query: 103 PTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPDGLPLLDGGPPLGPFADGA 162
S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPDGLP+ D +
Sbjct: 120 AMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPDGLPV-DASSVSNNYIQ-T 177
Query: 163 LDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE---PRDSPSYGSLSRGLGM 210
L R F G GGP ATL R + G+ E P S +YGSLSR +
Sbjct: 178 LGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGGSDNYGSLSRVTRI 237
Query: 211 RPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP-ERFQAEPYGLEDDTRSL 268
R P G + P ++ + GP+P GG S+ RF EPYGLEDD RS+
Sbjct: 238 EE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSM 289
Query: 269 AADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGELADERPAFPMVTAPLAQP 328
DD + DYGTA R R+YED + +E P+ APLAQ
Sbjct: 290 GYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------IGEEVPSDQYYWAPLAQH 342
Query: 329 ERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFE 388
ERGS+ SLD L + P P WR PELPEV+AML +D VK+NAAAYLQHLC+
Sbjct: 343 ERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYR 396
Query: 389 NEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPAL 448
N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+GRD DNK AI++C GVPAL
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456
Query: 449 VRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDS 508
VRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT EVI+PHSGWEREPNED
Sbjct: 457 VRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC 516
Query: 509 KPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSV 568
KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL+ +Q+ +G+KD+D+K V
Sbjct: 517 KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLV 576
Query: 569 ENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFH 628
ENCVC++RNLSY VH+E+P A+RYQEA P + + G ASCFG KK K+EWF
Sbjct: 577 ENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-----ASCFGAKKGKDEWFS 630
Query: 629 QGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQ 688
+GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SLL ES+ LEA+AGA+Q
Sbjct: 631 RGKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQ 689
Query: 689 NLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGS 748
NL AG W + YIR+ +R+E+ L + +LL +E ++VV+A + ALRNL++D RNK+LIG
Sbjct: 690 NLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGK 749
Query: 749 YAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVA 808
+A+ LV+N+ Q EDTV+++LNTI+E+++++L+ A+ L + +G+ LV
Sbjct: 750 HAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVL 807
Query: 809 LVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAKGPKGALSPGG 867
+ S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ FQ A + + S
Sbjct: 808 INKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHS--- 864
Query: 868 FDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYSTVDRRERRPRGASSAGEAS 921
+DDSTLPL+D++ + +K R+ I M +G + YST + R R +G+
Sbjct: 865 YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLDRSGDLG 924
Query: 922 EKEPLK 927
+ EPLK
Sbjct: 925 DMEPLK 930
>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 765 bits (1976), Expect = 0.0
Identities = 457/966 (47%), Positives = 605/966 (62%), Gaps = 81/966 (8%)
Query: 1 MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQ------QPGMVSGGM 54
M+D V S ASILASVKEQEA+FE+LTRALE+ERRHV+ QLER + P M +G +
Sbjct: 1 MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTL 60
Query: 55 ----------GSGQPLPMAWQQLVLQEQSPGSQASLATMP--EAPDVLEETVTVEEDPGT 102
G + L L S +T+P + P + ET T EEDP
Sbjct: 61 TRRHQNGRFVGDADLERQKFSDLKLNGPQDHSHLLYSTIPRMQEPGQIVETYT-EEDPEG 119
Query: 103 PTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPDGLPLLDGGPPLGPFADGA 162
S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPDGLP+ D +
Sbjct: 120 AMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPDGLPV-DASSVSNNYIQ-T 177
Query: 163 LDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE---PRDSPSYGSLSRGLGM 210
L R F G GGP ATL R + G+ E P S +YGSLSR +
Sbjct: 178 LGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGGSDNYGSLSRVTRI 237
Query: 211 RPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP-ERFQAEPYGLEDDTRSL 268
R P G + P ++ + GP+P GG S+ RF EPYGLEDD RS+
Sbjct: 238 EE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSM 289
Query: 269 AADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGELADERPAFPMVTAPLAQP 328
DD + DYGTA R R+YED + +E P+ APLAQ
Sbjct: 290 GYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------IGEEVPSDQYYWAPLAQH 342
Query: 329 ERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFE 388
ERGS+ SLD L + P P WR PELPEV+AML +D VK+NAAAYLQHLC+
Sbjct: 343 ERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYR 396
Query: 389 NEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPAL 448
N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+GRD DNK AI++C GVPAL
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456
Query: 449 VRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDS 508
VRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT EVI+PHSGWEREPNED
Sbjct: 457 VRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC 516
Query: 509 KPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSV 568
KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL+ +Q+ +G+KD+D+K V
Sbjct: 517 KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLV 576
Query: 569 ENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFH 628
ENCVC++RNLSY VH+E+P A+RYQEA P + + G ASCFG KK K
Sbjct: 577 ENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-----ASCFGAKKGK----- 625
Query: 629 QGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQ 688
GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SLL ES+ LEA+AGA+Q
Sbjct: 626 -GKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQ 683
Query: 689 NLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGS 748
NL AG W + YIR+ +R+E+ L + +LL +E ++VV+A + ALRNL++D RNK+LIG
Sbjct: 684 NLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGK 743
Query: 749 YAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVA 808
+A+ LV+N+ Q EDTV+++LNTI+E+++++L+ A+ L + +G+ LV
Sbjct: 744 HAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVL 801
Query: 809 LVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAKGPKGALSPGG 867
+ S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ FQ A + + S
Sbjct: 802 INKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHS--- 858
Query: 868 FDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYSTVDRRERRPRGASSAGEAS 921
+DDSTLPL+D++ + +K R+ I M +G + YST + R R +G+
Sbjct: 859 YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLDRSGDLG 918
Query: 922 EKEPLK 927
+ EPLK
Sbjct: 919 DMEPLK 924
>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 765 bits (1976), Expect = 0.0
Identities = 457/966 (47%), Positives = 605/966 (62%), Gaps = 81/966 (8%)
Query: 1 MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQ------QPGMVSGGM 54
M+D V S ASILASVKEQEA+FE+LTRALE+ERRHV+ QLER + P M +G +
Sbjct: 1 MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTL 60
Query: 55 ----------GSGQPLPMAWQQLVLQEQSPGSQASLATMP--EAPDVLEETVTVEEDPGT 102
G + L L S +T+P + P + ET T EEDP
Sbjct: 61 TRRHQNGRFVGDADLERQKFSDLKLNGPQDHSHLLYSTIPRMQEPGQIVETYT-EEDPEG 119
Query: 103 PTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPDGLPLLDGGPPLGPFADGA 162
S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPDGLP+ D +
Sbjct: 120 AMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPDGLPV-DASSVSNNYIQ-T 177
Query: 163 LDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE---PRDSPSYGSLSRGLGM 210
L R F G GGP ATL R + G+ E P S +YGSLSR +
Sbjct: 178 LGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGGSDNYGSLSRVTRI 237
Query: 211 RPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP-ERFQAEPYGLEDDTRSL 268
R P G + P ++ + GP+P GG S+ RF EPYGLEDD RS+
Sbjct: 238 EE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSM 289
Query: 269 AADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGELADERPAFPMVTAPLAQP 328
DD + DYGTA R R+YED + +E P+ APLAQ
Sbjct: 290 GYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------IGEEVPSDQYYWAPLAQH 342
Query: 329 ERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFE 388
ERGS+ SLD L + P P WR PELPEV+AML +D VK+NAAAYLQHLC+
Sbjct: 343 ERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYR 396
Query: 389 NEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPAL 448
N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+GRD DNK AI++C GVPAL
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456
Query: 449 VRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDS 508
VRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT EVI+PHSGWEREPNED
Sbjct: 457 VRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC 516
Query: 509 KPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSV 568
KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL+ +Q+ +G+KD+D+K V
Sbjct: 517 KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLV 576
Query: 569 ENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFH 628
ENCVC++RNLSY VH+E+P A+RYQEA P + + G ASCFG KK K
Sbjct: 577 ENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-----ASCFGAKKGK----- 625
Query: 629 QGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQ 688
GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SLL ES+ LEA+AGA+Q
Sbjct: 626 -GKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQ 683
Query: 689 NLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGS 748
NL AG W + YIR+ +R+E+ L + +LL +E ++VV+A + ALRNL++D RNK+LIG
Sbjct: 684 NLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGK 743
Query: 749 YAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVA 808
+A+ LV+N+ Q EDTV+++LNTI+E+++++L+ A+ L + +G+ LV
Sbjct: 744 HAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVL 801
Query: 809 LVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAKGPKGALSPGG 867
+ S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ FQ A + + S
Sbjct: 802 INKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHS--- 858
Query: 868 FDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYSTVDRRERRPRGASSAGEAS 921
+DDSTLPL+D++ + +K R+ I M +G + YST + R R +G+
Sbjct: 859 YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLDRSGDLG 918
Query: 922 EKEPLK 927
+ EPLK
Sbjct: 919 DMEPLK 924
>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 765 bits (1976), Expect = 0.0
Identities = 457/966 (47%), Positives = 605/966 (62%), Gaps = 81/966 (8%)
Query: 1 MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQ------QPGMVSGGM 54
M+D V S ASILASVKEQEA+FE+LTRALE+ERRHV+ QLER + P M +G +
Sbjct: 1 MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTL 60
Query: 55 ----------GSGQPLPMAWQQLVLQEQSPGSQASLATMP--EAPDVLEETVTVEEDPGT 102
G + L L S +T+P + P + ET T EEDP
Sbjct: 61 TRRHQNGRFVGDADLERQKFSDLKLNGPQDHSHLLYSTIPRMQEPGQIVETYT-EEDPEG 119
Query: 103 PTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPDGLPLLDGGPPLGPFADGA 162
S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPDGLP+ D +
Sbjct: 120 AMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPDGLPV-DASSVSNNYIQ-T 177
Query: 163 LDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE---PRDSPSYGSLSRGLGM 210
L R F G GGP ATL R + G+ E P S +YGSLSR +
Sbjct: 178 LGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGGSDNYGSLSRVTRI 237
Query: 211 RPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP-ERFQAEPYGLEDDTRSL 268
R P G + P ++ + GP+P GG S+ RF EPYGLEDD RS+
Sbjct: 238 EE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSM 289
Query: 269 AADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGELADERPAFPMVTAPLAQP 328
DD + DYGTA R R+YED + +E P+ APLAQ
Sbjct: 290 GYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------IGEEVPSDQYYWAPLAQH 342
Query: 329 ERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFE 388
ERGS+ SLD L + P P WR PELPEV+AML +D VK+NAAAYLQHLC+
Sbjct: 343 ERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYR 396
Query: 389 NEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPAL 448
N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+GRD DNK AI++C GVPAL
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456
Query: 449 VRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDS 508
VRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT EVI+PHSGWEREPNED
Sbjct: 457 VRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC 516
Query: 509 KPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSV 568
KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL+ +Q+ +G+KD+D+K V
Sbjct: 517 KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLV 576
Query: 569 ENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFH 628
ENCVC++RNLSY VH+E+P A+RYQEA P + + G ASCFG KK K
Sbjct: 577 ENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-----ASCFGAKKGK----- 625
Query: 629 QGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQ 688
GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SLL ES+ LEA+AGA+Q
Sbjct: 626 -GKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQ 683
Query: 689 NLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGS 748
NL AG W + YIR+ +R+E+ L + +LL +E ++VV+A + ALRNL++D RNK+LIG
Sbjct: 684 NLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGK 743
Query: 749 YAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVA 808
+A+ LV+N+ Q EDTV+++LNTI+E+++++L+ A+ L + +G+ LV
Sbjct: 744 HAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVL 801
Query: 809 LVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAKGPKGALSPGG 867
+ S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ FQ A + + S
Sbjct: 802 INKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHS--- 858
Query: 868 FDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYSTVDRRERRPRGASSAGEAS 921
+DDSTLPL+D++ + +K R+ I M +G + YST + R R +G+
Sbjct: 859 YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLDRSGDLG 918
Query: 922 EKEPLK 927
+ EPLK
Sbjct: 919 DMEPLK 924
>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
Length = 962
Score = 765 bits (1976), Expect = 0.0
Identities = 457/966 (47%), Positives = 605/966 (62%), Gaps = 81/966 (8%)
Query: 1 MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQ------QPGMVSGGM 54
M+D V S ASILASVKEQEA+FE+LTRALE+ERRHV+ QLER + P M +G +
Sbjct: 1 MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTL 60
Query: 55 ----------GSGQPLPMAWQQLVLQEQSPGSQASLATMP--EAPDVLEETVTVEEDPGT 102
G + L L S +T+P + P + ET T EEDP
Sbjct: 61 TRRHQNGRFVGDADLERQKFSDLKLNGPQDHSHLLYSTIPRMQEPGQIVETYT-EEDPEG 119
Query: 103 PTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPDGLPLLDGGPPLGPFADGA 162
S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPDGLP+ D +
Sbjct: 120 AMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPDGLPV-DASSVSNNYIQ-T 177
Query: 163 LDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE---PRDSPSYGSLSRGLGM 210
L R F G GGP ATL R + G+ E P S +YGSLSR +
Sbjct: 178 LGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGGSDNYGSLSRVTRI 237
Query: 211 RPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP-ERFQAEPYGLEDDTRSL 268
R P G + P ++ + GP+P GG S+ RF EPYGLEDD RS+
Sbjct: 238 EE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSM 289
Query: 269 AADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGELADERPAFPMVTAPLAQP 328
DD + DYGTA R R+YED + +E P+ APLAQ
Sbjct: 290 GYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------IGEEVPSDQYYWAPLAQH 342
Query: 329 ERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFE 388
ERGS+ SLD L + P P WR PELPEV+AML +D VK+NAAAYLQHLC+
Sbjct: 343 ERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYR 396
Query: 389 NEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPAL 448
N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+GRD DNK AI++C GVPAL
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456
Query: 449 VRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDS 508
VRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT EVI+PHSGWEREPNED
Sbjct: 457 VRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC 516
Query: 509 KPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSV 568
KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL+ +Q+ +G+KD+D+K V
Sbjct: 517 KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLV 576
Query: 569 ENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFH 628
ENCVC++RNLSY VH+E+P A+RYQEA P + + G ASCFG KK K
Sbjct: 577 ENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-----ASCFGAKKGK----- 625
Query: 629 QGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQ 688
GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SLL ES+ LEA+AGA+Q
Sbjct: 626 -GKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQ 683
Query: 689 NLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGS 748
NL AG W + YIR+ +R+E+ L + +LL +E ++VV+A + ALRNL++D RNK+LIG
Sbjct: 684 NLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGK 743
Query: 749 YAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVA 808
+A+ LV+N+ Q EDTV+++LNTI+E+++++L+ A+ L + +G+ LV
Sbjct: 744 HAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVL 801
Query: 809 LVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAKGPKGALSPGG 867
+ S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ FQ A + + S
Sbjct: 802 INKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHS--- 858
Query: 868 FDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYSTVDRRERRPRGASSAGEAS 921
+DDSTLPL+D++ + +K R+ I M +G + YST + R R +G+
Sbjct: 859 YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLDRSGDLG 918
Query: 922 EKEPLK 927
+ EPLK
Sbjct: 919 DMEPLK 924
>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
Length = 941
Score = 754 bits (1947), Expect = 0.0
Identities = 452/960 (47%), Positives = 598/960 (62%), Gaps = 90/960 (9%)
Query: 1 MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQ------QPGMVSGGM 54
M+D V S ASILASVKEQEA+FE+LTRALE+ERRHV+ QLER + P M +G +
Sbjct: 1 MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTL 60
Query: 55 ----------GSGQPLPMAWQQLVLQEQSPGSQASLATMP--EAPDVLEETVTVEEDPGT 102
G + L L S +T+P + P + ET T EEDP
Sbjct: 61 TRRHQNGRFVGDADLERQKFSDLKLNGPQDHSHLLYSTIPRMQEPGQIVETYT-EEDPEG 119
Query: 103 PTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPDGLPLLDGGPPLGPFADGA 162
S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPDGLP+ D +
Sbjct: 120 AMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPDGLPV-DASSVSNNYIQ-T 177
Query: 163 LDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE---PRDSPSYGSLSRGLGM 210
L R F G GGP ATL R + G+ E P S +YGSLSR +
Sbjct: 178 LGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGGSDNYGSLSRVTRI 237
Query: 211 RPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP-ERFQAEPYGLEDDTRSL 268
R P G + P ++ + GP+P GG S+ RF EPYGLEDD RS+
Sbjct: 238 EE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSM 289
Query: 269 AADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGELADERPAFPMVTAPLAQP 328
DD + DYGTA R R+YED + +E P+ APLAQ
Sbjct: 290 GYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------IGEEVPSDQYYWAPLAQH 342
Query: 329 ERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFE 388
ERGS+ SLD L + P P WR PELPEV+AML +D VK+NAAAYLQHLC+
Sbjct: 343 ERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYR 396
Query: 389 NEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPAL 448
N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+GRD DNK AI++C GVPAL
Sbjct: 397 NDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPAL 456
Query: 449 VRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDS 508
VRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT EVI+PHSGWEREPNED
Sbjct: 457 VRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC 516
Query: 509 KPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSV 568
KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL+ +Q+ +G+KD+D+K V
Sbjct: 517 KPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLV 576
Query: 569 ENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFH 628
ENCVC++RNLSY VH+E+P A+RYQEA P + + G ASCFG KK K
Sbjct: 577 ENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-----ASCFGAKKGK----- 625
Query: 629 QGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQ 688
GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SLL ES+ LEA+AGA+Q
Sbjct: 626 -GKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQ 683
Query: 689 NLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGS 748
NL AG W + YIR+ +R+E+ L + +LL +E ++VV+A + ALRNL++D RNK+LIG
Sbjct: 684 NLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGK 743
Query: 749 YAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVA 808
+A+ LV+N+ Q EDTV+++LNTI+E+++++L+ A+ L + +G+ LV
Sbjct: 744 HAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVL 801
Query: 809 LVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAKGPKGALSPGG 867
+ S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ FQ A + + S
Sbjct: 802 INKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHS--- 858
Query: 868 FDDSTLPLVDKSLEGEKTGSRDVIPMDALGPDGYSTVDRRERRPRGASSAGEASEKEPLK 927
+DDSTLPL+D++ + + + YST + R R +G+ + EPLK
Sbjct: 859 YDDSTLPLIDRNQKSD---------------NNYSTPNERGDHNRTLDRSGDLGDMEPLK 903
>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
Length = 838
Score = 728 bits (1879), Expect = 0.0
Identities = 418/864 (48%), Positives = 557/864 (64%), Gaps = 57/864 (6%)
Query: 85 EAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPD 144
+ P + ET T EEDP S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPD
Sbjct: 2 QEPGQIVETYT-EEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPD 60
Query: 145 GLPLLDGGPPLGPFADGALDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE- 194
GLP+ D + L R F G GGP ATL R + G+ E
Sbjct: 61 GLPV-DASSVSNNYIQ-TLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYED 118
Query: 195 --PRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP 251
P S +YGSLSR + R P G + P ++ + GP+P GG S+
Sbjct: 119 GYPGGSDNYGSLSRVTRIEE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVD 170
Query: 252 -ERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGE 310
RF EPYGLEDD RS+ DD + DYGTA R R+YED
Sbjct: 171 LHRFHPEPYGLEDDQRSMGYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------ 223
Query: 311 LADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHP 370
+ +E P+ APLAQ ERGS+ SLD L + P P WR PELPEV+AML
Sbjct: 224 IGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFR 277
Query: 371 VDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYG 430
+D VK+NAAAYLQHLC+ N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+G
Sbjct: 278 LDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFG 337
Query: 431 RDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLT 490
RD DNK AI++C GVPALVRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT
Sbjct: 338 RDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALT 397
Query: 491 HEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDAL 550
EVI+PHSGWEREPNED KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL
Sbjct: 398 DEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDAL 457
Query: 551 LHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRR 610
+ +Q+ +G+KD+D+K VENCVC++RNLSY VH+E+P A+RYQEA P + + G
Sbjct: 458 IFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-- 514
Query: 611 RDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSL 670
ASCFG KK K+EWF +GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SL
Sbjct: 515 ---ASCFGAKKGKDEWFSRGKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISL 570
Query: 671 LTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVA 730
L ES+ LEA+AGA+QNL AG W + YIR+ +R+E+ L + +LL +E ++VV+A +
Sbjct: 571 LKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAAS 630
Query: 731 IALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDS 790
ALRNL++D RNK+LIG +A+ LV+N+ Q EDTV+++LNTI+E+++++
Sbjct: 631 GALRNLAVDARNKELIGKHAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAEN 688
Query: 791 LDNARSLLQARGVPALVALVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARF 849
L+ A+ L + +G+ LV + S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ F
Sbjct: 689 LEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDF 748
Query: 850 QSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYST 903
Q A + + S +DDSTLPL+D++ + +K R+ I M +G + YST
Sbjct: 749 QVNLNNASRSQSSHS---YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYST 805
Query: 904 VDRRERRPRGASSAGEASEKEPLK 927
+ R R +G+ + EPLK
Sbjct: 806 PNERGDHNRTLDRSGDLGDMEPLK 829
>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
Length = 867
Score = 728 bits (1879), Expect = 0.0
Identities = 418/864 (48%), Positives = 557/864 (64%), Gaps = 57/864 (6%)
Query: 85 EAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPD 144
+ P + ET T EEDP S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPD
Sbjct: 2 QEPGQIVETYT-EEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPD 60
Query: 145 GLPLLDGGPPLGPFADGALDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE- 194
GLP+ D + L R F G GGP ATL R + G+ E
Sbjct: 61 GLPV-DASSVSNNYIQ-TLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYED 118
Query: 195 --PRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP 251
P S +YGSLSR + R P G + P ++ + GP+P GG S+
Sbjct: 119 GYPGGSDNYGSLSRVTRIEE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVD 170
Query: 252 -ERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGE 310
RF EPYGLEDD RS+ DD + DYGTA R R+YED
Sbjct: 171 LHRFHPEPYGLEDDQRSMGYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------ 223
Query: 311 LADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHP 370
+ +E P+ APLAQ ERGS+ SLD L + P P WR PELPEV+AML
Sbjct: 224 IGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFR 277
Query: 371 VDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYG 430
+D VK+NAAAYLQHLC+ N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+G
Sbjct: 278 LDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFG 337
Query: 431 RDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLT 490
RD DNK AI++C GVPALVRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT
Sbjct: 338 RDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALT 397
Query: 491 HEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDAL 550
EVI+PHSGWEREPNED KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL
Sbjct: 398 DEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDAL 457
Query: 551 LHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRR 610
+ +Q+ +G+KD+D+K VENCVC++RNLSY VH+E+P A+RYQEA P + + G
Sbjct: 458 IFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-- 514
Query: 611 RDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSL 670
ASCFG KK K+EWF +GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SL
Sbjct: 515 ---ASCFGAKKGKDEWFSRGKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISL 570
Query: 671 LTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVA 730
L ES+ LEA+AGA+QNL AG W + YIR+ +R+E+ L + +LL +E ++VV+A +
Sbjct: 571 LKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAAS 630
Query: 731 IALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDS 790
ALRNL++D RNK+LIG +A+ LV+N+ Q EDTV+++LNTI+E+++++
Sbjct: 631 GALRNLAVDARNKELIGKHAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAEN 688
Query: 791 LDNARSLLQARGVPALVALVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARF 849
L+ A+ L + +G+ LV + S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ F
Sbjct: 689 LEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDF 748
Query: 850 QSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYST 903
Q A + + S +DDSTLPL+D++ + +K R+ I M +G + YST
Sbjct: 749 QVNLNNASRSQSSHS---YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYST 805
Query: 904 VDRRERRPRGASSAGEASEKEPLK 927
+ R R +G+ + EPLK
Sbjct: 806 PNERGDHNRTLDRSGDLGDMEPLK 829
>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 712 bits (1838), Expect = 0.0
Identities = 415/864 (48%), Positives = 552/864 (63%), Gaps = 63/864 (7%)
Query: 85 EAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPD 144
+ P + ET T EEDP S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPD
Sbjct: 2 QEPGQIVETYT-EEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPD 60
Query: 145 GLPLLDGGPPLGPFADGALDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE- 194
GLP+ D + L R F G GGP ATL R + G+ E
Sbjct: 61 GLPV-DASSVSNNYIQ-TLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYED 118
Query: 195 --PRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP 251
P S +YGSLSR + R P G + P ++ + GP+P GG S+
Sbjct: 119 GYPGGSDNYGSLSRVTRIEE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVD 170
Query: 252 -ERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGE 310
RF EPYGLEDD RS+ DD + DYGTA R R+YED
Sbjct: 171 LHRFHPEPYGLEDDQRSMGYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------ 223
Query: 311 LADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHP 370
+ +E P+ APLAQ ERGS+ SLD L + P P WR PELPEV+AML
Sbjct: 224 IGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFR 277
Query: 371 VDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYG 430
+D VK+NAAAYLQHLC+ N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+G
Sbjct: 278 LDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFG 337
Query: 431 RDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLT 490
RD DNK AI++C GVPALVRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT
Sbjct: 338 RDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALT 397
Query: 491 HEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDAL 550
EVI+PHSGWEREPNED KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL
Sbjct: 398 DEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDAL 457
Query: 551 LHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRR 610
+ +Q+ +G+KD+D+K VENCVC++RNLSY VH+E+P A+RYQEA P + + G
Sbjct: 458 IFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-- 514
Query: 611 RDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSL 670
ASCFG KK K GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SL
Sbjct: 515 ---ASCFGAKKGK------GKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISL 564
Query: 671 LTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVA 730
L ES+ LEA+AGA+QNL AG W + YIR+ +R+E+ L + +LL +E ++VV+A +
Sbjct: 565 LKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAAS 624
Query: 731 IALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDS 790
ALRNL++D RNK+LIG +A+ LV+N+ Q EDTV+++LNTI+E+++++
Sbjct: 625 GALRNLAVDARNKELIGKHAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAEN 682
Query: 791 LDNARSLLQARGVPALVALVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARF 849
L+ A+ L + +G+ LV + S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ F
Sbjct: 683 LEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDF 742
Query: 850 QSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYST 903
Q A + + S +DDSTLPL+D++ + +K R+ I M +G + YST
Sbjct: 743 QVNLNNASRSQSSHS---YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYST 799
Query: 904 VDRRERRPRGASSAGEASEKEPLK 927
+ R R +G+ + EPLK
Sbjct: 800 PNERGDHNRTLDRSGDLGDMEPLK 823
>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 712 bits (1838), Expect = 0.0
Identities = 415/864 (48%), Positives = 552/864 (63%), Gaps = 63/864 (7%)
Query: 85 EAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPD 144
+ P + ET T EEDP S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPD
Sbjct: 2 QEPGQIVETYT-EEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPD 60
Query: 145 GLPLLDGGPPLGPFADGALDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE- 194
GLP+ D + L R F G GGP ATL R + G+ E
Sbjct: 61 GLPV-DASSVSNNYIQ-TLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYED 118
Query: 195 --PRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP 251
P S +YGSLSR + R P G + P ++ + GP+P GG S+
Sbjct: 119 GYPGGSDNYGSLSRVTRIEE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVD 170
Query: 252 -ERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGE 310
RF EPYGLEDD RS+ DD + DYGTA R R+YED
Sbjct: 171 LHRFHPEPYGLEDDQRSMGYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------ 223
Query: 311 LADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHP 370
+ +E P+ APLAQ ERGS+ SLD L + P P WR PELPEV+AML
Sbjct: 224 IGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFR 277
Query: 371 VDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYG 430
+D VK+NAAAYLQHLC+ N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+G
Sbjct: 278 LDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFG 337
Query: 431 RDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLT 490
RD DNK AI++C GVPALVRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT
Sbjct: 338 RDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALT 397
Query: 491 HEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDAL 550
EVI+PHSGWEREPNED KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL
Sbjct: 398 DEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDAL 457
Query: 551 LHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRR 610
+ +Q+ +G+KD+D+K VENCVC++RNLSY VH+E+P A+RYQEA P + + G
Sbjct: 458 IFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-- 514
Query: 611 RDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSL 670
ASCFG KK K GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SL
Sbjct: 515 ---ASCFGAKKGK------GKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISL 564
Query: 671 LTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVA 730
L ES+ LEA+AGA+QNL AG W + YIR+ +R+E+ L + +LL +E ++VV+A +
Sbjct: 565 LKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAAS 624
Query: 731 IALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDS 790
ALRNL++D RNK+LIG +A+ LV+N+ Q EDTV+++LNTI+E+++++
Sbjct: 625 GALRNLAVDARNKELIGKHAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAEN 682
Query: 791 LDNARSLLQARGVPALVALVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARF 849
L+ A+ L + +G+ LV + S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ F
Sbjct: 683 LEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDF 742
Query: 850 QSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYST 903
Q A + + S +DDSTLPL+D++ + +K R+ I M +G + YST
Sbjct: 743 QVNLNNASRSQSSHS---YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYST 799
Query: 904 VDRRERRPRGASSAGEASEKEPLK 927
+ R R +G+ + EPLK
Sbjct: 800 PNERGDHNRTLDRSGDLGDMEPLK 823
>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 712 bits (1838), Expect = 0.0
Identities = 415/864 (48%), Positives = 552/864 (63%), Gaps = 63/864 (7%)
Query: 85 EAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPD 144
+ P + ET T EEDP S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPD
Sbjct: 2 QEPGQIVETYT-EEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPD 60
Query: 145 GLPLLDGGPPLGPFADGALDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE- 194
GLP+ D + L R F G GGP ATL R + G+ E
Sbjct: 61 GLPV-DASSVSNNYIQ-TLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYED 118
Query: 195 --PRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP 251
P S +YGSLSR + R P G + P ++ + GP+P GG S+
Sbjct: 119 GYPGGSDNYGSLSRVTRIEE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVD 170
Query: 252 -ERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGE 310
RF EPYGLEDD RS+ DD + DYGTA R R+YED
Sbjct: 171 LHRFHPEPYGLEDDQRSMGYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------ 223
Query: 311 LADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHP 370
+ +E P+ APLAQ ERGS+ SLD L + P P WR PELPEV+AML
Sbjct: 224 IGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFR 277
Query: 371 VDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYG 430
+D VK+NAAAYLQHLC+ N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+G
Sbjct: 278 LDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFG 337
Query: 431 RDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLT 490
RD DNK AI++C GVPALVRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT
Sbjct: 338 RDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALT 397
Query: 491 HEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDAL 550
EVI+PHSGWEREPNED KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL
Sbjct: 398 DEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDAL 457
Query: 551 LHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRR 610
+ +Q+ +G+KD+D+K VENCVC++RNLSY VH+E+P A+RYQEA P + + G
Sbjct: 458 IFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-- 514
Query: 611 RDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSL 670
ASCFG KK K GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SL
Sbjct: 515 ---ASCFGAKKGK------GKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISL 564
Query: 671 LTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVA 730
L ES+ LEA+AGA+QNL AG W + YIR+ +R+E+ L + +LL +E ++VV+A +
Sbjct: 565 LKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAAS 624
Query: 731 IALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDS 790
ALRNL++D RNK+LIG +A+ LV+N+ Q EDTV+++LNTI+E+++++
Sbjct: 625 GALRNLAVDARNKELIGKHAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAEN 682
Query: 791 LDNARSLLQARGVPALVALVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARF 849
L+ A+ L + +G+ LV + S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ F
Sbjct: 683 LEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDF 742
Query: 850 QSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYST 903
Q A + + S +DDSTLPL+D++ + +K R+ I M +G + YST
Sbjct: 743 QVNLNNASRSQSSHS---YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYST 799
Query: 904 VDRRERRPRGASSAGEASEKEPLK 927
+ R R +G+ + EPLK
Sbjct: 800 PNERGDHNRTLDRSGDLGDMEPLK 823
>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
Length = 861
Score = 712 bits (1838), Expect = 0.0
Identities = 415/864 (48%), Positives = 552/864 (63%), Gaps = 63/864 (7%)
Query: 85 EAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPD 144
+ P + ET T EEDP S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPD
Sbjct: 2 QEPGQIVETYT-EEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPD 60
Query: 145 GLPLLDGGPPLGPFADGALDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE- 194
GLP+ D + L R F G GGP ATL R + G+ E
Sbjct: 61 GLPV-DASSVSNNYIQ-TLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYED 118
Query: 195 --PRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP 251
P S +YGSLSR + R P G + P ++ + GP+P GG S+
Sbjct: 119 GYPGGSDNYGSLSRVTRIEE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVD 170
Query: 252 -ERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGE 310
RF EPYGLEDD RS+ DD + DYGTA R R+YED
Sbjct: 171 LHRFHPEPYGLEDDQRSMGYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------ 223
Query: 311 LADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHP 370
+ +E P+ APLAQ ERGS+ SLD L + P P WR PELPEV+AML
Sbjct: 224 IGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFR 277
Query: 371 VDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYG 430
+D VK+NAAAYLQHLC+ N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+G
Sbjct: 278 LDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFG 337
Query: 431 RDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLT 490
RD DNK AI++C GVPALVRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT
Sbjct: 338 RDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALT 397
Query: 491 HEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDAL 550
EVI+PHSGWEREPNED KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL
Sbjct: 398 DEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDAL 457
Query: 551 LHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRR 610
+ +Q+ +G+KD+D+K VENCVC++RNLSY VH+E+P A+RYQEA P + + G
Sbjct: 458 IFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-- 514
Query: 611 RDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSL 670
ASCFG KK K GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SL
Sbjct: 515 ---ASCFGAKKGK------GKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISL 564
Query: 671 LTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVA 730
L ES+ LEA+AGA+QNL AG W + YIR+ +R+E+ L + +LL +E ++VV+A +
Sbjct: 565 LKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAAS 624
Query: 731 IALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDS 790
ALRNL++D RNK+LIG +A+ LV+N+ Q EDTV+++LNTI+E+++++
Sbjct: 625 GALRNLAVDARNKELIGKHAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAEN 682
Query: 791 LDNARSLLQARGVPALVALVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARF 849
L+ A+ L + +G+ LV + S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ F
Sbjct: 683 LEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDF 742
Query: 850 QSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALG------PDGYST 903
Q A + + S +DDSTLPL+D++ + +K R+ I M +G + YST
Sbjct: 743 QVNLNNASRSQSSHS---YDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYST 799
Query: 904 VDRRERRPRGASSAGEASEKEPLK 927
+ R R +G+ + EPLK
Sbjct: 800 PNERGDHNRTLDRSGDLGDMEPLK 823
>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
Length = 840
Score = 701 bits (1809), Expect = 0.0
Identities = 410/858 (47%), Positives = 545/858 (63%), Gaps = 72/858 (8%)
Query: 85 EAPDVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPVGPD 144
+ P + ET T EEDP S VS+ TS+DGTTRRTET V K VKTVTTRTV+ V +GPD
Sbjct: 2 QEPGQIVETYT-EEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPD 60
Query: 145 GLPLLDGGPPLGPFADGALDRHFLLRG-GGP--------VATLSRAYLSSGGGFPEGPE- 194
GLP+ D + L R F G GGP ATL R + G+ E
Sbjct: 61 GLPV-DASSVSNNYIQ-TLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYED 118
Query: 195 --PRDSPSYGSLSRGLGMRPPRAGPLGPGPGDGCFTLPGHREAFPVGPEPGPP-GGRSLP 251
P S +YGSLSR + R P G + P ++ + GP+P GG S+
Sbjct: 119 GYPGGSDNYGSLSRVTRIEE-RYRPSMEG-----YRAPSRQDVY--GPQPQVRVGGSSVD 170
Query: 252 -ERFQAEPYGLEDDTRSLAADDEGGPELEPDYGTATRRRPECGRGLHTRAYEDTADDGGE 310
RF EPYGLEDD RS+ DD + DYGTA R R+YED
Sbjct: 171 LHRFHPEPYGLEDDQRSMGYDDLDYGMMS-DYGTARRTGTPSDPRRRLRSYEDM------ 223
Query: 311 LADERPAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHP 370
+ +E P+ APLAQ ERGS+ SLD L + P P WR PELPEV+AML
Sbjct: 224 IGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPP------PPNWRQPELPEVIAMLGFR 277
Query: 371 VDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYG 430
+D VK+NAAAYLQHLC+ N+ VK VR+L+G+P+LV LLDHP+ EV ACGAL+N+S+G
Sbjct: 278 LDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFG 337
Query: 431 RDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLT 490
RD DNK AI++C GVPALVRLLR ARD ++ E++TGTLWNLSS++ +KM I+DH L LT
Sbjct: 338 RDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALT 397
Query: 491 HEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDAL 550
EVI+PHSGWEREPNED KPR EW +V NT+GCLRNVSS+ +EARR+LREC+GLVDAL
Sbjct: 398 DEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDAL 457
Query: 551 LHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRR 610
+ +Q+ +G+KD+D+K VENCVC++RNLSY VH+E+P A+RYQEA P + + G
Sbjct: 458 IFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN-VANNTGPHA-- 514
Query: 611 RDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSL 670
ASCFG KK K GKK E N DT+D PKRT A+G+ELL+QPEVVR+Y+SL
Sbjct: 515 ---ASCFGAKKGK------GKKPIEDPAN-DTVDFPKRTSPARGYELLFQPEVVRIYISL 564
Query: 671 LTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVA 730
L ES+ LEA+AGA+QNL AG W + YIR+ +R+E+ L + +LL +E ++VV+A +
Sbjct: 565 LKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAAS 624
Query: 731 IALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDS 790
ALRNL++D RNK+LIG +A+ LV+N+ Q EDTV+++LNTI+E+++++
Sbjct: 625 GALRNLAVDARNKELIGKHAIPNLVKNLPGGQ--QNSSWNFSEDTVISILNTINEVIAEN 682
Query: 791 LDNARSLLQARGVPALVALVAS-SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARF 849
L+ A+ L + +G+ LV + S ++S +E +AA+ VLQT+W YKELR L+K+GW K+ F
Sbjct: 683 LEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDF 742
Query: 850 QSAAATAKGPKGALSPGGFDDSTLPLVDKSLEGEKTGSRDVIPMDALGPDGYSTVDRRER 909
Q A + + S +DDSTLPL+D++ + + + YST + R
Sbjct: 743 QVNLNNASRSQSSHS---YDDSTLPLIDRNQKSD---------------NNYSTPNERGD 784
Query: 910 RPRGASSAGEASEKEPLK 927
R +G+ + EPLK
Sbjct: 785 HNRTLDRSGDLGDMEPLK 802
>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
plakophilin-related arm-repeat protein) [Homo sapiens]
Length = 1225
Score = 488 bits (1257), Expect = e-138
Identities = 261/524 (49%), Positives = 352/524 (67%), Gaps = 22/524 (4%)
Query: 342 RSPSVDSARKEPR---WRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQ 398
RSPS+DS +K+PR WRDPELPEV+ ML+H V++NAAAYLQHLCF + +K +R+
Sbjct: 531 RSPSIDSIQKDPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRR 590
Query: 399 LRGLPLLVALLDHPRAEVRRRACGALRNLSYGR-DTDNKAAIRDCGGVPALVRLLRAARD 457
G+ LLV LLDH EV R ACGALRNL YG+ + DNK A+++CGG+PALVRLLR D
Sbjct: 591 QGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTD 650
Query: 458 NEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTT 517
E+RELVTG LWNLSS + LKM II L LT+ VI+PHSGWE P +D + +
Sbjct: 651 LEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQ 710
Query: 518 VFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRN 577
V +N +GCLRNVSS G EARRR+REC+GL DALL+ +QSA+G + D+K+VENCVCI+RN
Sbjct: 711 VLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRN 770
Query: 578 LSYHVHKEVPGADRYQEAEPGPL--GSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGE 635
LSY + E E L G A G + + + C+G KK K++ Q + DG
Sbjct: 771 LSYRLAAETSQGQHMGTDELDGLLCGEANG---KDAESSGCWGKKKKKKK--SQDQWDG- 824
Query: 636 MDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNW 695
LP E KG ++L+ P +V+ YL+LL+E N +TLE AAGALQNL+AG+W
Sbjct: 825 ------VGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSW 878
Query: 696 MWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELV 755
W+ YIRA VRKE+GLP+LVELL+ + D+VV AVA ALRN++LD RNK+LIG YAM +LV
Sbjct: 879 KWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLV 938
Query: 756 RNVRNAQAPPRPGA-CLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALVAS-- 812
+ + + +DTV AV T+HE+++ +++NA++L A G+ LV + S
Sbjct: 939 HRLPGGNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKG 998
Query: 813 -SQSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAAT 855
S + KAAS VL ++W Y++LR +KDGW++ F ++++T
Sbjct: 999 DKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSST 1042
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/262 (30%), Positives = 99/262 (37%), Gaps = 55/262 (20%)
Query: 8 SAASILASVKEQEARFERLTRALEQERRHVALQLERAQQPGMVSGGMG--SGQPLPMAWQ 65
+ ++ILASVKEQE +FERLTR LE ER+ VA QLER + G +G M S WQ
Sbjct: 47 TTSAILASVKEQELQFERLTRELEAERQIVASQLERCKL-GSETGSMSSMSSAEEQFQWQ 105
Query: 66 Q------------------------------LVLQEQSPGSQASLATMPEAPDVLEETVT 95
L Q+ S G + SL + L+
Sbjct: 106 SQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDYSTGERPSLLSQ----SALQLNSK 161
Query: 96 VEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVP-------VGPDGLPL 148
E P S+ S T G T ++ T T ++ Q GP+ P
Sbjct: 162 PEGSFQYPASYHSNQTLALGETTPSQLPARGTQARATGQSFSQGTTSRAGHLAGPEPAP- 220
Query: 149 LDGGPPLGPFADGALDRHFLLRGGGPVATLSRAYLSSG--GGFPEGPEPRDSPSYGS--- 203
PP PFA +L F L P A + Y SS P G P +P GS
Sbjct: 221 PPPPPPREPFAP-SLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTK 279
Query: 204 LSRGLGMRP---PRAGPLGPGP 222
L RG G P A P G P
Sbjct: 280 LQRG-GSAPEGATYAAPRGSSP 300
>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
Length = 1192
Score = 472 bits (1215), Expect = e-133
Identities = 271/606 (44%), Positives = 377/606 (62%), Gaps = 32/606 (5%)
Query: 342 RSPSVDSARKEPR---WRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQ 398
RSPS+DS +K+PR WRDPELPEV+ ML+H V+ANAAAYLQHLCF + VK V +
Sbjct: 509 RSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCR 568
Query: 399 LRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTD-NKAAIRDCGGVPALVRLLRAARD 457
L G+ LV LLDH EV++ ACGALRNL +G+ TD NK A+++ GG+PAL+RLLR + D
Sbjct: 569 LGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSID 628
Query: 458 NEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTT 517
EVRELVTG LWNLSS + +KM II L TLT+ VIVPHSGW +D + +
Sbjct: 629 AEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSL 688
Query: 518 VFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRN 577
V +NT+GCLRN+SS G EAR+++R CEGLVD+LL+ + + V D D+K+VENCVC +RN
Sbjct: 689 VLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRN 748
Query: 578 LSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRD-DASCFGGKKAKEEWFHQGKKDGEM 636
LSY + EVP A E L +G + +D + SC+G KK K+ K+ +
Sbjct: 749 LSYRLELEVPQARLLGLNE---LDDLLGKESPSKDSEPSCWGKKKKKK------KRTPQE 799
Query: 637 DRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWM 696
D+ +P +++ KG E+L+ P VV+ YL+LL ES N TLE +AG+LQNLSAGNW
Sbjct: 800 DQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWK 859
Query: 697 WATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVR 756
+A YIRA VRKE+GLP+LVELL+ + D+VV +VA ALRN++LD RNK+LIG YAM +LV
Sbjct: 860 FAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVN 919
Query: 757 NVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALV---ASS 813
+ P + L ++T+ A+ +HE+ S +++NA++L + G+ LV +
Sbjct: 920 RLPGGNGP----SVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDR 975
Query: 814 QSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAKGPKGALSP--GGFDDS 871
S++ KAA+ VL T+W Y++LR +KDGW + F + +T + + P +
Sbjct: 976 SSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQ 1035
Query: 872 TLPLVDKSLEGEKTGSRDVIPMDALGPDGYSTVDRRERRPRGASSAGEASEKEPLKLDPS 931
P++ + GS P D S DR + + +S G+A+ K L P
Sbjct: 1036 MSPII------QSVGSTSSSPALLGIRDPRSEYDRTQPPMQYYNSQGDATHK---GLYPG 1086
Query: 932 RKAPPP 937
P P
Sbjct: 1087 SSKPSP 1092
Score = 48.9 bits (115), Expect = 2e-05
Identities = 28/48 (58%), Positives = 35/48 (72%), Gaps = 4/48 (8%)
Query: 8 SAASILASVKEQEARFERLTRALEQERRHVALQLER----AQQPGMVS 51
+A +ILASVKEQE +F+RLTR LE ER+ VA QLER A+ P + S
Sbjct: 33 TATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIAS 80
>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
Length = 1149
Score = 471 bits (1211), Expect = e-132
Identities = 254/522 (48%), Positives = 349/522 (66%), Gaps = 21/522 (4%)
Query: 342 RSPSVDSARKEPR---WRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQ 398
RSPS+DS +K+PR WRDPELPEV+ ML+H V+ANAAAYLQHLCF + VK V +
Sbjct: 509 RSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCR 568
Query: 399 LRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTD-NKAAIRDCGGVPALVRLLRAARD 457
L G+ LV LLDH EV++ ACGALRNL +G+ TD NK A+++ GG+PAL+RLLR + D
Sbjct: 569 LGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSID 628
Query: 458 NEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTT 517
EVRELVTG LWNLSS + +KM II L TLT+ VIVPHSGW +D + +
Sbjct: 629 AEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSL 688
Query: 518 VFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRN 577
V +NT+GCLRN+SS G EAR+++R CEGLVD+LL+ + + V D D+K+VENCVC +RN
Sbjct: 689 VLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRN 748
Query: 578 LSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRD-DASCFGGKKAKEEWFHQGKKDGEM 636
LSY + EVP A E L +G + +D + SC+G KK K+ K+ +
Sbjct: 749 LSYRLELEVPQARLLGLNE---LDDLLGKESPSKDSEPSCWGKKKKKK------KRTPQE 799
Query: 637 DRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWM 696
D+ +P +++ KG E+L+ P VV+ YL+LL ES N TLE +AG+LQNLSAGNW
Sbjct: 800 DQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWK 859
Query: 697 WATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVR 756
+A YIRA VRKE+GLP+LVELL+ + D+VV +VA ALRN++LD RNK+LIG YAM +LV
Sbjct: 860 FAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVN 919
Query: 757 NVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALV---ASS 813
+ P + L ++T+ A+ +HE+ S +++NA++L + G+ LV +
Sbjct: 920 RLPGGNGP----SVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDR 975
Query: 814 QSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAAT 855
S++ KAA+ VL T+W Y++LR +KDGW + F + +T
Sbjct: 976 SSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVST 1017
Score = 48.9 bits (115), Expect = 2e-05
Identities = 28/48 (58%), Positives = 35/48 (72%), Gaps = 4/48 (8%)
Query: 8 SAASILASVKEQEARFERLTRALEQERRHVALQLER----AQQPGMVS 51
+A +ILASVKEQE +F+RLTR LE ER+ VA QLER A+ P + S
Sbjct: 33 TATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIAS 80
>gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
Length = 837
Score = 265 bits (676), Expect = 2e-70
Identities = 178/538 (33%), Positives = 278/538 (51%), Gaps = 33/538 (6%)
Query: 325 LAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLR--HPVDPVKANAAAYL 382
+ Q G G+L L RS DS + L ++ML H + + AA ++
Sbjct: 321 VGQAAAGGSGNL--LTERSTFTDSQLGNADM-EMTLERAVSMLEADHMLPSRISAAATFI 377
Query: 383 QHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDC 442
QH CF+ ++RV QLRG+ L+ LL +V+R CGALRNL + D DNK + +
Sbjct: 378 QHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDNKLEVAEL 436
Query: 443 GGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWER 502
GVP L+++L+ RD E ++ +TG LWNLSS + LK ++I L TLT +I+P SGW
Sbjct: 437 NGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE 496
Query: 503 EPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKD 562
+ K +F N +GCLRN+SS GA+ R+ +R C+GL+D+L+H ++ +
Sbjct: 497 --GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQ 554
Query: 563 TDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKA 622
D+K+ ENCVCI+ NLSY + E+P ++Y + Q CFG +
Sbjct: 555 PDDKATENCVCILHNLSYQLEAELP--EKYSQ---NIYIQNRNIQTDNNKSIGCFGSRSR 609
Query: 623 KEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEA 682
K + + + +P+ KG E L+ V+R+YLSL+ +S T EA
Sbjct: 610 K------------VKEQYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEA 657
Query: 683 AAGALQNLSAGNWMWATYIRAT-VRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRR 741
+ GALQNL+AG+ T + T V+KE GL ++L V + LRNLS +
Sbjct: 658 SLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLS 717
Query: 742 NKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQAR 801
++ I + +LV + + P L +T + T++ I+ +S NAR LL
Sbjct: 718 LQNEIAKETLPDLVSIIPDTV----PSTDLLIETTASACYTLNNIIQNSYQNARDLLNTG 773
Query: 802 GVPALVALVASS--QSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAK 857
G+ ++A+ A S + +KAAS +L ++W++ EL +K + K F + + TAK
Sbjct: 774 GIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFVN-SRTAK 830
>gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
Length = 726
Score = 247 bits (630), Expect = 4e-65
Identities = 167/489 (34%), Positives = 255/489 (52%), Gaps = 30/489 (6%)
Query: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
+P+ + L + +A A Y+QH CF++E K++V QL G+ LV LL P V++
Sbjct: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
Query: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
A GALRNL + R T NK R G+ V LLR + E+++ +TG LWNLSS + LK
Sbjct: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
Query: 480 VIIDHGLQTLTHEVIVPHSGW-EREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARR 538
+I L L VI+P SGW + N + D E VF N +GCLRN+SS A R+
Sbjct: 366 ELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE---VFFNATGCLRNLSSADA-GRQ 421
Query: 539 RLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPG 598
+R GL+D+L+ +Q+ V D+KSVENC+C++ NLSY + EVP RY++ E
Sbjct: 422 TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYN 479
Query: 599 PLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELL 658
+ + CF K D M+ N+D LP+ KG L
Sbjct: 480 ARNAYT-----EKSSTGCF-----------SNKSDKMMNNNYD-CPLPEEETNPKGSGWL 522
Query: 659 YQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATV-RKERGLPVLVEL 717
Y + +R YL+L+ +S+ TLEA AGALQNL+A + ++ + + KE+GLP + L
Sbjct: 523 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARL 582
Query: 718 LQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVV 777
LQS VVR+ A L N+S ++G+ E+ R + + ED +
Sbjct: 583 LQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTG----NTSNSEDILS 638
Query: 778 AVLNTIHEIVSDSLDNARSLLQARGVPALVALVASSQSVREAKAASHVLQTVWSYKELRG 837
+ T+ +++ A+ + + ++ L SS S + A+AA +L +WS KEL+G
Sbjct: 639 SACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQG 698
Query: 838 TLQKDGWTK 846
L++ G+ +
Sbjct: 699 VLRQQGFDR 707
>gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
sapiens]
Length = 625
Score = 247 bits (630), Expect = 4e-65
Identities = 167/489 (34%), Positives = 255/489 (52%), Gaps = 30/489 (6%)
Query: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
+P+ + L + +A A Y+QH CF++E K++V QL G+ LV LL P V++
Sbjct: 146 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205
Query: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
A GALRNL + R T NK R G+ V LLR + E+++ +TG LWNLSS + LK
Sbjct: 206 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 264
Query: 480 VIIDHGLQTLTHEVIVPHSGW-EREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARR 538
+I L L VI+P SGW + N + D E VF N +GCLRN+SS A R+
Sbjct: 265 ELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE---VFFNATGCLRNLSSADA-GRQ 320
Query: 539 RLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPG 598
+R GL+D+L+ +Q+ V D+KSVENC+C++ NLSY + EVP RY++ E
Sbjct: 321 TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYN 378
Query: 599 PLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELL 658
+ + CF K D M+ N+D LP+ KG L
Sbjct: 379 ARNAYT-----EKSSTGCF-----------SNKSDKMMNNNYD-CPLPEEETNPKGSGWL 421
Query: 659 YQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATV-RKERGLPVLVEL 717
Y + +R YL+L+ +S+ TLEA AGALQNL+A + ++ + + KE+GLP + L
Sbjct: 422 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARL 481
Query: 718 LQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVV 777
LQS VVR+ A L N+S ++G+ E+ R + + ED +
Sbjct: 482 LQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTG----NTSNSEDILS 537
Query: 778 AVLNTIHEIVSDSLDNARSLLQARGVPALVALVASSQSVREAKAASHVLQTVWSYKELRG 837
+ T+ +++ A+ + + ++ L SS S + A+AA +L +WS KEL+G
Sbjct: 538 SACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQG 597
Query: 838 TLQKDGWTK 846
L++ G+ +
Sbjct: 598 VLRQQGFDR 606
>gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
Length = 881
Score = 243 bits (621), Expect = 5e-64
Identities = 178/582 (30%), Positives = 278/582 (47%), Gaps = 77/582 (13%)
Query: 325 LAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLR--HPVDPVKANAAAYL 382
+ Q G G+L L RS DS + L ++ML H + + AA ++
Sbjct: 321 VGQAAAGGSGNL--LTERSTFTDSQLGNADM-EMTLERAVSMLEADHMLPSRISAAATFI 377
Query: 383 QHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDC 442
QH CF+ ++RV QLRG+ L+ LL +V+R CGALRNL + D DNK + +
Sbjct: 378 QHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDNKLEVAEL 436
Query: 443 GGVPALVRLLRAARDNEVRELVT------------------------------------- 465
GVP L+++L+ RD E ++ +T
Sbjct: 437 NGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGV 496
Query: 466 -------GTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTV 518
G LWNLSS + LK ++I L TLT +I+P SGW + K +
Sbjct: 497 RDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE--GDYPKANGLLDFDI 554
Query: 519 FKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNL 578
F N +GCLRN+SS GA+ R+ +R C+GL+D+L+H ++ + D+K+ ENCVCI+ NL
Sbjct: 555 FYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNL 614
Query: 579 SYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDR 638
SY + E+P ++Y + Q CFG + K +
Sbjct: 615 SYQLEAELP--EKYSQ---NIYIQNRNIQTDNNKSIGCFGSRSRK------------VKE 657
Query: 639 NFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWA 698
+ + +P+ KG E L+ V+R+YLSL+ +S T EA+ GALQNL+AG+
Sbjct: 658 QYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMP 717
Query: 699 TYIRAT-VRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRN 757
T + T V+KE GL ++L V + LRNLS + ++ I + +LV
Sbjct: 718 TSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSI 777
Query: 758 VRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALVASS--QS 815
+ + P L +T + T++ I+ +S NAR LL G+ ++A+ A S
Sbjct: 778 IPDTV----PSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYAS 833
Query: 816 VREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAK 857
+ +KAAS +L ++W++ EL +K + K F + + TAK
Sbjct: 834 NKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFVN-SRTAK 874
>gi|6005830 plakophilin 3 [Homo sapiens]
Length = 797
Score = 243 bits (619), Expect = 8e-64
Identities = 170/498 (34%), Positives = 268/498 (53%), Gaps = 26/498 (5%)
Query: 357 DPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEV 416
D +LP + L ++ AAY+QH C+ + K++ R L+ +P LV L +H EV
Sbjct: 318 DIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEV 377
Query: 417 RRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEP 476
+R A GA+RNL Y + DNK A+ + G+ L+R LR +D+E+R+ VTG LWNLSS +
Sbjct: 378 QRHATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDH 435
Query: 477 LKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEA 536
LK + L+ LT V+ P SG P +AE +F N +G LRN+SS
Sbjct: 436 LKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQAT 492
Query: 537 RRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAE 596
R+++REC GLVDAL+ ++ A+ ++KSVEN VC++RNLSY ++ E+P
Sbjct: 493 RQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMP--------- 543
Query: 597 PGPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFE 656
P L G R RRD A G + + Q ++ E+ D L + ++ KG E
Sbjct: 544 PSALQRLEG--RGRRDLAGAPPG-EVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLE 600
Query: 657 LLYQPEVVRLYLSLLTESR-NFNTLEAAAGALQNLSAGNWMWATYI-RATVRKERGLPVL 714
L+ P++V LY LL N +T EAAAGALQN++AG+ WA + R + +ER L L
Sbjct: 601 WLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPL 660
Query: 715 VELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEED 774
++ +++ +R++ +RNLS + RNKD + + ++ L+ + + P A +
Sbjct: 661 LDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPA----E 716
Query: 775 TVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALVA---SSQSVREAKAASHVLQTVWS 831
+V ++ ++ +V S AR LL G+ L+ + S S + ++AAS +L +W
Sbjct: 717 VLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQ 776
Query: 832 YKELRGTLQKDGWTKARF 849
Y +L + G+ K F
Sbjct: 777 YNKLHRDFRAKGYRKEDF 794
>gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
Length = 747
Score = 234 bits (598), Expect = 2e-61
Identities = 167/510 (32%), Positives = 255/510 (50%), Gaps = 51/510 (10%)
Query: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
+P+ + L + +A A Y+QH CF++E K++V QL G+ LV LL P V++
Sbjct: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
Query: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
A GALRNL + R T NK R G+ V LLR + E+++ +TG LWNLSS + LK
Sbjct: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
Query: 480 VIIDHGLQTLTHEVIVPHSGW-EREPNEDSKPRDAEWTTVFKNTSGCLR----------- 527
+I L L VI+P SGW + N + D E VF N +GCLR
Sbjct: 366 ELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE---VFFNATGCLRKRLGMRELLAL 422
Query: 528 ----------NVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRN 577
N+SS A R+ +R GL+D+L+ +Q+ V D+KSVENC+C++ N
Sbjct: 423 VPQRATSSRVNLSSADA-GRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN 481
Query: 578 LSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMD 637
LSY + EVP RY++ E + + CF K D M+
Sbjct: 482 LSYRLDAEVP--TRYRQLEYNARNAYT-----EKSSTGCF-----------SNKSDKMMN 523
Query: 638 RNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMW 697
N+D LP+ KG LY + +R YL+L+ +S+ TLEA AGALQNL+A +
Sbjct: 524 NNYD-CPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLM 582
Query: 698 ATYIRATV-RKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVR 756
++ + + KE+GLP + LLQS VVR+ A L N+S ++G+ E+ R
Sbjct: 583 SSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTR 642
Query: 757 NVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALVASSQSV 816
+ + ED + + T+ +++ A+ + + ++ L SS S
Sbjct: 643 LLTSHTG----NTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASP 698
Query: 817 REAKAASHVLQTVWSYKELRGTLQKDGWTK 846
+ A+AA +L +WS KEL+G L++ G+ +
Sbjct: 699 KAAEAARLLLSDMWSSKELQGVLRQQGFDR 728
>gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 54.3 bits (129), Expect = 5e-07
Identities = 94/404 (23%), Positives = 154/404 (38%), Gaps = 66/404 (16%)
Query: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
+P ++ ML PVD V A L +L EG K VR GL +VALL+ +
Sbjct: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
Query: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
L+ L+YG + ++K I GG ALV ++R ++ + L LS K
Sbjct: 297 TTDCLQILAYG-NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKP 355
Query: 480 VIID-HGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARR 538
I++ G+Q L + P + +N LRN+S +A
Sbjct: 356 AIVEAGGMQALGLHLTDPSQ------------------RLVQNCLWTLRNLS----DAAT 393
Query: 539 RLRECEGLVDALLHALQSAVGRKDTDNKSVENCVC-IMRNLSYHVHKEVPGADRYQEAEP 597
+ EGL+ L+ L S D+ +V C I+ NL+ + +K ++ +
Sbjct: 394 KQEGMEGLLGTLVQLLGS-------DDINVVTCAAGILSNLTCNNYK-----NKMMVCQV 441
Query: 598 GPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFEL 657
G + + V + R D ++ EM +N L
Sbjct: 442 GGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN--------------AVRL 487
Query: 658 LYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVEL 717
Y VV + LL ++ ++A G ++NL+ A +R++ +P LV+L
Sbjct: 488 HYGLPVV---VKLLHPPSHWPLIKATVGLIRNLAL-----CPANHAPLREQGAIPRLVQL 539
Query: 718 LQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNA 761
L VRA R S+ + + M E+V A
Sbjct: 540 L-------VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGA 576
Score = 44.3 bits (103), Expect = 6e-04
Identities = 51/195 (26%), Positives = 89/195 (45%), Gaps = 17/195 (8%)
Query: 301 YEDTADDGGELADER--PAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDP 358
+ +T D+G ++ + A P LA+P + ++ L+ + A +
Sbjct: 99 FPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRA------ 152
Query: 359 ELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRV-RQLRGLPLLVALLDHPR-AEV 416
+PE+ +L D V N AA + H + E + + R + + +V + + E
Sbjct: 153 -IPELTKLLNDE-DQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVET 210
Query: 417 RRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSY-E 475
R G L NLS+ R+ AI GG+PALV++L + D+ + +T TL NL + E
Sbjct: 211 ARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQE 267
Query: 476 PLKMVI-IDHGLQTL 489
KM + + GLQ +
Sbjct: 268 GAKMAVRLAGGLQKM 282
Score = 31.2 bits (69), Expect = 4.9
Identities = 54/209 (25%), Positives = 85/209 (40%), Gaps = 46/209 (22%)
Query: 402 LPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVR-LLRAARDNEV 460
L LV LL V A G L NL+ + NK + GG+ ALVR +LRA ++
Sbjct: 402 LGTLVQLLGSDDINVVTCAAGILSNLTCN-NYKNKMMVCQVGGIEALVRTVLRAGDREDI 460
Query: 461 RELVTGTLWNLSS-YEPLKM----VIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEW 515
E L +L+S ++ +M V + +GL + +++ P S W
Sbjct: 461 TEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVV-KLLHPPSHW--------------- 504
Query: 516 TTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKS-------- 567
+ K T G +RN++ A LRE +G + L+ L A +DT ++
Sbjct: 505 -PLIKATVGLIRNLALCPAN-HAPLRE-QGAIPRLVQLLVRA--HQDTQRRTSMGGTQQQ 559
Query: 568 ----------VENCVCIMRNLSYHVHKEV 586
VE C + L+ VH +
Sbjct: 560 FVEGVRMEEIVEGCTGALHILARDVHNRI 588
>gi|148233338 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 54.3 bits (129), Expect = 5e-07
Identities = 94/404 (23%), Positives = 154/404 (38%), Gaps = 66/404 (16%)
Query: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
+P ++ ML PVD V A L +L EG K VR GL +VALL+ +
Sbjct: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
Query: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
L+ L+YG + ++K I GG ALV ++R ++ + L LS K
Sbjct: 297 TTDCLQILAYG-NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKP 355
Query: 480 VIID-HGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARR 538
I++ G+Q L + P + +N LRN+S +A
Sbjct: 356 AIVEAGGMQALGLHLTDPSQ------------------RLVQNCLWTLRNLS----DAAT 393
Query: 539 RLRECEGLVDALLHALQSAVGRKDTDNKSVENCVC-IMRNLSYHVHKEVPGADRYQEAEP 597
+ EGL+ L+ L S D+ +V C I+ NL+ + +K ++ +
Sbjct: 394 KQEGMEGLLGTLVQLLGS-------DDINVVTCAAGILSNLTCNNYK-----NKMMVCQV 441
Query: 598 GPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFEL 657
G + + V + R D ++ EM +N L
Sbjct: 442 GGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN--------------AVRL 487
Query: 658 LYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVEL 717
Y VV + LL ++ ++A G ++NL+ A +R++ +P LV+L
Sbjct: 488 HYGLPVV---VKLLHPPSHWPLIKATVGLIRNLAL-----CPANHAPLREQGAIPRLVQL 539
Query: 718 LQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNA 761
L VRA R S+ + + M E+V A
Sbjct: 540 L-------VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGA 576
Score = 44.3 bits (103), Expect = 6e-04
Identities = 51/195 (26%), Positives = 89/195 (45%), Gaps = 17/195 (8%)
Query: 301 YEDTADDGGELADER--PAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDP 358
+ +T D+G ++ + A P LA+P + ++ L+ + A +
Sbjct: 99 FPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRA------ 152
Query: 359 ELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRV-RQLRGLPLLVALLDHPR-AEV 416
+PE+ +L D V N AA + H + E + + R + + +V + + E
Sbjct: 153 -IPELTKLLNDE-DQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVET 210
Query: 417 RRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSY-E 475
R G L NLS+ R+ AI GG+PALV++L + D+ + +T TL NL + E
Sbjct: 211 ARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQE 267
Query: 476 PLKMVI-IDHGLQTL 489
KM + + GLQ +
Sbjct: 268 GAKMAVRLAGGLQKM 282
Score = 31.2 bits (69), Expect = 4.9
Identities = 54/209 (25%), Positives = 85/209 (40%), Gaps = 46/209 (22%)
Query: 402 LPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVR-LLRAARDNEV 460
L LV LL V A G L NL+ + NK + GG+ ALVR +LRA ++
Sbjct: 402 LGTLVQLLGSDDINVVTCAAGILSNLTCN-NYKNKMMVCQVGGIEALVRTVLRAGDREDI 460
Query: 461 RELVTGTLWNLSS-YEPLKM----VIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEW 515
E L +L+S ++ +M V + +GL + +++ P S W
Sbjct: 461 TEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVV-KLLHPPSHW--------------- 504
Query: 516 TTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKS-------- 567
+ K T G +RN++ A LRE +G + L+ L A +DT ++
Sbjct: 505 -PLIKATVGLIRNLALCPAN-HAPLRE-QGAIPRLVQLLVRA--HQDTQRRTSMGGTQQQ 559
Query: 568 ----------VENCVCIMRNLSYHVHKEV 586
VE C + L+ VH +
Sbjct: 560 FVEGVRMEEIVEGCTGALHILARDVHNRI 588
>gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 54.3 bits (129), Expect = 5e-07
Identities = 94/404 (23%), Positives = 154/404 (38%), Gaps = 66/404 (16%)
Query: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
+P ++ ML PVD V A L +L EG K VR GL +VALL+ +
Sbjct: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
Query: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
L+ L+YG + ++K I GG ALV ++R ++ + L LS K
Sbjct: 297 TTDCLQILAYG-NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKP 355
Query: 480 VIID-HGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARR 538
I++ G+Q L + P + +N LRN+S +A
Sbjct: 356 AIVEAGGMQALGLHLTDPSQ------------------RLVQNCLWTLRNLS----DAAT 393
Query: 539 RLRECEGLVDALLHALQSAVGRKDTDNKSVENCVC-IMRNLSYHVHKEVPGADRYQEAEP 597
+ EGL+ L+ L S D+ +V C I+ NL+ + +K ++ +
Sbjct: 394 KQEGMEGLLGTLVQLLGS-------DDINVVTCAAGILSNLTCNNYK-----NKMMVCQV 441
Query: 598 GPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFEL 657
G + + V + R D ++ EM +N L
Sbjct: 442 GGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN--------------AVRL 487
Query: 658 LYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVEL 717
Y VV + LL ++ ++A G ++NL+ A +R++ +P LV+L
Sbjct: 488 HYGLPVV---VKLLHPPSHWPLIKATVGLIRNLAL-----CPANHAPLREQGAIPRLVQL 539
Query: 718 LQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNA 761
L VRA R S+ + + M E+V A
Sbjct: 540 L-------VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGA 576
Score = 44.3 bits (103), Expect = 6e-04
Identities = 51/195 (26%), Positives = 89/195 (45%), Gaps = 17/195 (8%)
Query: 301 YEDTADDGGELADER--PAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDP 358
+ +T D+G ++ + A P LA+P + ++ L+ + A +
Sbjct: 99 FPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRA------ 152
Query: 359 ELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRV-RQLRGLPLLVALLDHPR-AEV 416
+PE+ +L D V N AA + H + E + + R + + +V + + E
Sbjct: 153 -IPELTKLLNDE-DQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVET 210
Query: 417 RRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSY-E 475
R G L NLS+ R+ AI GG+PALV++L + D+ + +T TL NL + E
Sbjct: 211 ARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQE 267
Query: 476 PLKMVI-IDHGLQTL 489
KM + + GLQ +
Sbjct: 268 GAKMAVRLAGGLQKM 282
Score = 31.2 bits (69), Expect = 4.9
Identities = 54/209 (25%), Positives = 85/209 (40%), Gaps = 46/209 (22%)
Query: 402 LPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVR-LLRAARDNEV 460
L LV LL V A G L NL+ + NK + GG+ ALVR +LRA ++
Sbjct: 402 LGTLVQLLGSDDINVVTCAAGILSNLTCN-NYKNKMMVCQVGGIEALVRTVLRAGDREDI 460
Query: 461 RELVTGTLWNLSS-YEPLKM----VIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEW 515
E L +L+S ++ +M V + +GL + +++ P S W
Sbjct: 461 TEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVV-KLLHPPSHW--------------- 504
Query: 516 TTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKS-------- 567
+ K T G +RN++ A LRE +G + L+ L A +DT ++
Sbjct: 505 -PLIKATVGLIRNLALCPAN-HAPLRE-QGAIPRLVQLLVRA--HQDTQRRTSMGGTQQQ 559
Query: 568 ----------VENCVCIMRNLSYHVHKEV 586
VE C + L+ VH +
Sbjct: 560 FVEGVRMEEIVEGCTGALHILARDVHNRI 588
>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
Length = 872
Score = 54.3 bits (129), Expect = 5e-07
Identities = 56/194 (28%), Positives = 87/194 (44%), Gaps = 23/194 (11%)
Query: 363 VLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACG 422
++A+L D K A+ + +C EN G K +G+P L+ LL EVR A
Sbjct: 321 LVALLGSENDGTKIAASQAISAMC-ENSGSKDFFNN-QGIPQLIQLLKSDNEEVREAAAL 378
Query: 423 ALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVII 482
AL NL+ + AA + G+ L+ LL + RD + T L N++ EPL++ I
Sbjct: 379 ALANLTTCNPANANAA-AEADGIDPLINLLSSKRDGAIANAAT-VLTNMAMQEPLRLNIQ 436
Query: 483 DHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRE 542
+H + H +I P R N TV ++ + ++ EAR LR
Sbjct: 437 NHDIM---HAIISP----LRSAN-----------TVVQSKAALAVTATACDVEARTELRN 478
Query: 543 CEGLVDALLHALQS 556
GL + L+ L+S
Sbjct: 479 SGGL-EPLVELLRS 491
Score = 47.8 bits (112), Expect = 5e-05
Identities = 103/494 (20%), Positives = 197/494 (39%), Gaps = 82/494 (16%)
Query: 363 VLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACG 422
V+ ML P + + A A + + E K + +L + L LL H VRR A
Sbjct: 30 VVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATM 89
Query: 423 ALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVII 482
L+ D K +R+ + +++ L + + E + L N+S+ K+ I
Sbjct: 90 IFGILASNNDV--KKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIF 147
Query: 483 DH-GLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLR 541
+H GL+ L + P+ D K KN+ C+ N+ D + R +L+
Sbjct: 148 EHGGLEPLIRLL--------SSPDPDVK----------KNSMECIYNLVQD-FQCRAKLQ 188
Query: 542 ECEGLVDAL--------------LHALQSAVGRKDT-----DNKSVENCVCIMRNL---S 579
E + L L L K++ DN+ +++ + I+
Sbjct: 189 ELNAIPPILDLLKSEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKILETKELND 248
Query: 580 YHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRN 639
H+ A+ ++ + + V Q+ GG K K F + ++ +N
Sbjct: 249 LHIEALAVIANCLED-----MDTMVQIQQT--------GGLK-KLLSFAENSTIPDIQKN 294
Query: 640 FDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWAT 699
+ K + +L ++ EV + ++LL S N T AA+ A+ + +
Sbjct: 295 -AAKAITKAAYDPENRKLFHEQEVEKCLVALL-GSENDGTKIAASQAISAMCENSGSKDF 352
Query: 700 YIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVR 759
+ +G+P L++LL+S+ ++V A A+AL NL+ N + A A+ + +
Sbjct: 353 F------NNQGIPQLIQLLKSDNEEVREAAALALANLT--TCNPANANAAAEADGIDPLI 404
Query: 760 NAQAPPRPGACLEEDTVVAVL-------------NTIHEIVSDSLDNARSLLQARGVPAL 806
N + R GA TV+ + + +H I+S L +A +++Q++ A+
Sbjct: 405 NLLSSKRDGAIANAATVLTNMAMQEPLRLNIQNHDIMHAIIS-PLRSANTVVQSKAALAV 463
Query: 807 VALVASSQSVREAK 820
A ++ E +
Sbjct: 464 TATACDVEARTELR 477
Score = 31.6 bits (70), Expect = 3.7
Identities = 33/128 (25%), Positives = 61/128 (47%), Gaps = 8/128 (6%)
Query: 335 SLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKR 394
+L L +P+ +A E DP ++ +L D ANAA L ++ + E ++
Sbjct: 379 ALANLTTCNPANANAAAEADGIDP----LINLLSSKRDGAIANAATVLTNMAMQ-EPLRL 433
Query: 395 RVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRA 454
++ + +++ L V+ +A AL + D + + +R+ GG+ LV LLR+
Sbjct: 434 NIQNHDIMHAIISPLRSANTVVQSKA--ALAVTATACDVEARTELRNSGGLEPLVELLRS 491
Query: 455 ARDNEVRE 462
D EVR+
Sbjct: 492 KND-EVRK 498
>gi|31657114 armadillo repeat containing 4 [Homo sapiens]
Length = 1044
Score = 53.5 bits (127), Expect = 9e-07
Identities = 44/135 (32%), Positives = 66/135 (48%), Gaps = 15/135 (11%)
Query: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLD--------- 410
LP ++ +L P +K AA + ++ + + +R VRQ G+ LVALLD
Sbjct: 537 LPIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPA 595
Query: 411 ----HPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTG 466
+ +V CGAL S + NK AIR GG+P L RLL+ + +N + +V G
Sbjct: 596 QSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVV-G 654
Query: 467 TLWNLSSYEPLKMVI 481
TL +S E + I
Sbjct: 655 TLQECASEENYRAAI 669
Score = 38.5 bits (88), Expect = 0.031
Identities = 47/183 (25%), Positives = 70/183 (38%), Gaps = 35/183 (19%)
Query: 395 RVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRA 454
+ R+ + + LV LL EV GAL R+ N+ +R CGG+ LV LL
Sbjct: 751 KFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERE--NRVIVRKCGGIQPLVNLLVG 808
Query: 455 ARDNEVRELVTGTLWNLSSYEPLKMVIIDH--GLQTLTHEVIVPHSGWE--REPNEDSKP 510
N+ + + EP M+IID G++ L W + P+ D K
Sbjct: 809 I--NQALLVNVTKAVGACAVEPESMMIIDRLDGVRLL----------WSLLKNPHPDVK- 855
Query: 511 RDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVEN 570
A W C++N G +V + + L+ V +DNK V
Sbjct: 856 ASAAWA-----LCPCIKNAKDAGE-----------MVRSFVGGLELIVNLLKSDNKEVLA 899
Query: 571 CVC 573
VC
Sbjct: 900 SVC 902
Score = 37.4 bits (85), Expect = 0.068
Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 389 NEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPAL 448
N +++ + L GLP++V +LD P ++ A + N++ + + +R GG+ L
Sbjct: 524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKRA--RRVVRQHGGITKL 581
Query: 449 VRLLRAARDN 458
V LL A D+
Sbjct: 582 VALLDCAHDS 591
>gi|4504811 junction plakoglobin [Homo sapiens]
Length = 745
Score = 50.8 bits (120), Expect = 6e-06
Identities = 60/242 (24%), Positives = 103/242 (42%), Gaps = 28/242 (11%)
Query: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
+P ++ ML PV+ V A L +L EG K VR GL +V LL+ +
Sbjct: 228 IPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAI 287
Query: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
L+ L+YG + ++K I GG ALV+++R ++ + L LS K
Sbjct: 288 TTDCLQLLAYG-NQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKP 346
Query: 480 VIID-HGLQTLTHEV------IVPHSGWEREPNEDSKPRDAEWTTVFK------------ 520
I++ G+Q L + +V + W D + +V K
Sbjct: 347 AIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVN 406
Query: 521 ---NTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRN 577
+G L N++ + ++ + + + G V+AL+HA+ A + D E VC +R+
Sbjct: 407 VLTCATGTLSNLTCNNSKNKTLVTQNSG-VEALIHAILRAGDKDDI----TEPAVCALRH 461
Query: 578 LS 579
L+
Sbjct: 462 LT 463
Score = 42.7 bits (99), Expect = 0.002
Identities = 54/179 (30%), Positives = 79/179 (44%), Gaps = 21/179 (11%)
Query: 325 LAQPERGSMGSLDRLVRRSPSVDSA-------RKEPRWRDPELPEVLAMLRHPVDPVKAN 377
LA G +L RL S + SA + + LPE+ +L DPV
Sbjct: 102 LATQVEGQATNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDE-DPVVVT 160
Query: 378 AAAYLQHLCFENEGVKRRVRQLRGLPLLVALL-----DHPRAEVRRRACGALRNLSYGRD 432
AA + + + E +R L G P LVA + + + R L NLS+ R+
Sbjct: 161 KAAMIVNQLSKKEASRRA---LMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHRE 217
Query: 433 TDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSY-EPLKMVI-IDHGLQTL 489
AI GG+PALVR+L + ++ + +T TL NL Y E KM + + GLQ +
Sbjct: 218 --GLLAIFKSGGIPALVRMLSSPVESVLFYAIT-TLHNLLLYQEGAKMAVRLADGLQKM 273
>gi|12056468 junction plakoglobin [Homo sapiens]
Length = 745
Score = 50.8 bits (120), Expect = 6e-06
Identities = 60/242 (24%), Positives = 103/242 (42%), Gaps = 28/242 (11%)
Query: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
+P ++ ML PV+ V A L +L EG K VR GL +V LL+ +
Sbjct: 228 IPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAI 287
Query: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
L+ L+YG + ++K I GG ALV+++R ++ + L LS K
Sbjct: 288 TTDCLQLLAYG-NQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKP 346
Query: 480 VIID-HGLQTLTHEV------IVPHSGWEREPNEDSKPRDAEWTTVFK------------ 520
I++ G+Q L + +V + W D + +V K
Sbjct: 347 AIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVN 406
Query: 521 ---NTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRN 577
+G L N++ + ++ + + + G V+AL+HA+ A + D E VC +R+
Sbjct: 407 VLTCATGTLSNLTCNNSKNKTLVTQNSG-VEALIHAILRAGDKDDI----TEPAVCALRH 461
Query: 578 LS 579
L+
Sbjct: 462 LT 463
Score = 42.7 bits (99), Expect = 0.002
Identities = 54/179 (30%), Positives = 79/179 (44%), Gaps = 21/179 (11%)
Query: 325 LAQPERGSMGSLDRLVRRSPSVDSA-------RKEPRWRDPELPEVLAMLRHPVDPVKAN 377
LA G +L RL S + SA + + LPE+ +L DPV
Sbjct: 102 LATQVEGQATNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDE-DPVVVT 160
Query: 378 AAAYLQHLCFENEGVKRRVRQLRGLPLLVALL-----DHPRAEVRRRACGALRNLSYGRD 432
AA + + + E +R L G P LVA + + + R L NLS+ R+
Sbjct: 161 KAAMIVNQLSKKEASRRA---LMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHRE 217
Query: 433 TDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSY-EPLKMVI-IDHGLQTL 489
AI GG+PALVR+L + ++ + +T TL NL Y E KM + + GLQ +
Sbjct: 218 --GLLAIFKSGGIPALVRMLSSPVESVLFYAIT-TLHNLLLYQEGAKMAVRLADGLQKM 273
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,594,675
Number of Sequences: 37866
Number of extensions: 2525967
Number of successful extensions: 9561
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 309
Number of HSP's that attempted gapping in prelim test: 8319
Number of HSP's gapped (non-prelim): 1271
length of query: 962
length of database: 18,247,518
effective HSP length: 112
effective length of query: 850
effective length of database: 14,006,526
effective search space: 11905547100
effective search space used: 11905547100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.