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Search of human proteins with 42764683
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42764683 dual specificity phosphatase 6 isoform a [Homo
sapiens]
(381 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 767 0.0
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 535 e-152
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 367 e-101
gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens] 270 2e-72
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 186 4e-47
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 173 2e-43
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 169 4e-42
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 166 3e-41
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 162 4e-40
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 157 1e-38
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 156 3e-38
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 144 1e-34
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 123 3e-28
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 123 3e-28
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 100 2e-21
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 100 2e-21
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 100 2e-21
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 97 2e-20
gi|37674210 slingshot 2 [Homo sapiens] 96 7e-20
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 95 1e-19
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 90 3e-18
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 80 3e-15
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 79 9e-15
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 79 9e-15
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 79 9e-15
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 76 4e-14
gi|239582767 slingshot homolog 3 [Homo sapiens] 74 3e-13
gi|6005956 dual specificity phosphatase 12 [Homo sapiens] 69 5e-12
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 69 5e-12
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 69 7e-12
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 767 bits (1980), Expect = 0.0
Identities = 381/381 (100%), Positives = 381/381 (100%)
Query: 1 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG 60
MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
Sbjct: 1 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG 60
Query: 61 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK 120
IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK
Sbjct: 61 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK 120
Query: 121 KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI 180
KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
Sbjct: 121 KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI 180
Query: 181 ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT 240
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
Sbjct: 181 ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT 240
Query: 241 PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS 300
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
Sbjct: 241 PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS 300
Query: 301 VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ 360
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
Sbjct: 301 VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ 360
Query: 361 QLYFTTPSNQNVYQVDSLQST 381
QLYFTTPSNQNVYQVDSLQST
Sbjct: 361 QLYFTTPSNQNVYQVDSLQST 381
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 535 bits (1377), Expect = e-152
Identities = 264/367 (71%), Positives = 314/367 (85%), Gaps = 5/367 (1%)
Query: 18 KTVAWLNEQLEL-GNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRAL 76
K+ WL E+LE G LLL+DCRP EL+ESSHIE+AIN+AIPG+MLRRL+KGNLP+R++
Sbjct: 55 KSAEWLQEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSI 114
Query: 77 FTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGE-SVLGLLLKKLKDEGCRAFYLEGG 135
D++RF RC TV+LYDE++++W G SVLGLLL+KL+D+GC+A+YL+GG
Sbjct: 115 IPNHADKERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGG 174
Query: 136 FSKFQAEFSLHCETNLDGSCS-SSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDS 194
F+KFQ E+S HCETN+D S S SSSPP VLGLGGLRISSD S D ESD + P+SAT+S
Sbjct: 175 FNKFQTEYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCS-DGESDREL-PSSATES 232
Query: 195 DGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFK 254
DGSP+ +SQP+FPV+ILP+LYLGCAKDSTNLDVL ++GIKYILNVTPNLPN FE+ GEF
Sbjct: 233 DGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFT 292
Query: 255 YKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNL 314
YKQIPISDHWSQNLSQFFPEAISFIDEAR K CGVLVHCLAGISRSVTVTVAYLMQK+NL
Sbjct: 293 YKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNL 352
Query: 315 SMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQ 374
S+NDAYD VK KKSNISPNFNFMGQLLDFERTLGLSSPCDN ++QLYF+TP+N N++
Sbjct: 353 SLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFP 412
Query: 375 VDSLQST 381
+++L+ST
Sbjct: 413 LNTLEST 419
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 367 bits (941), Expect = e-101
Identities = 207/384 (53%), Positives = 259/384 (67%), Gaps = 30/384 (7%)
Query: 16 ISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRA 75
+ ++ WL +L RLLL+DCR +ELYES+ I A++VA+P ++LRRL++G+L VRA
Sbjct: 4 LGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRA 63
Query: 76 LFTRGEDRDRFTRRCGTDTVVLYDESSSDWN--------ENTGGESVLGLLLKKLKDEGC 127
L + V+LYD+ E ESVLG LL+KL++EG
Sbjct: 64 LLPGPP-----LQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGY 118
Query: 128 RAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLP----VLGLGGLRISSDSSSDIESD 183
A+YL+GGFS+FQAE CET+L G SS P+P V+GLG L + SD S D ES+
Sbjct: 119 LAYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCS-DAESE 177
Query: 184 LDRDPNSA-TDSDGS--PLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT 240
DRD S DS+G+ P + SFPV+ILP LYLG A+DS NL+ L + GI+YILNVT
Sbjct: 178 ADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVT 237
Query: 241 PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS 300
PNLPN FE G+F YKQIPISDHWSQNLS+FFPEAI FIDEA +NCGVLVHCLAG+SRS
Sbjct: 238 PNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRS 297
Query: 301 VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGL---------SS 351
VTVTVAYLMQKL+LS+NDAYD+VK KKSNISPNFNFMGQLLDFER+L L S
Sbjct: 298 VTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSG 357
Query: 352 PCDNRVPAQQLYFTTPSNQNVYQV 375
+ +FTTP++ +++
Sbjct: 358 GQASAASNPPSFFTTPTSDGAFEL 381
>gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens]
Length = 235
Score = 270 bits (690), Expect = 2e-72
Identities = 136/154 (88%), Positives = 138/154 (89%)
Query: 1 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG 60
MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
Sbjct: 1 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG 60
Query: 61 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK 120
IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK
Sbjct: 61 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK 120
Query: 121 KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGS 154
KLKDEGCRAFYLE +HC + S
Sbjct: 121 KLKDEGCRAFYLEDEARGKNCGVLVHCLAGISRS 154
Score = 207 bits (527), Expect = 1e-53
Identities = 102/102 (100%), Positives = 102/102 (100%)
Query: 280 DEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQ 339
DEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQ
Sbjct: 134 DEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQ 193
Query: 340 LLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST 381
LLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
Sbjct: 194 LLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST 235
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 186 bits (471), Expect = 4e-47
Identities = 113/314 (35%), Positives = 172/314 (54%), Gaps = 25/314 (7%)
Query: 35 LLMDCRPQELYESSHIESAINV-AIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTD 93
+++DCRP Y SHI+ A+++ I RRLQ+G + V L + E +D F +R +
Sbjct: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSF-KRIFSK 231
Query: 94 TVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDG 153
+++YDE++++ + + L ++L+ LK EG L+GG S F+ C+ +L
Sbjct: 232 EIIVYDENTNEPSRVMPSQP-LHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQ- 289
Query: 154 SCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPF 213
L R +S S L + + D + + L+ ILPF
Sbjct: 290 -------------LQECREVGGGASAASSLLPQPIPTTPDIENAELT--------PILPF 328
Query: 214 LYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFP 273
L+LG +D+ +LD ++ I Y++NVT +LP G F YK++P +D QNL Q+F
Sbjct: 329 LFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFE 388
Query: 274 EAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPN 333
EA FI+EA G+L+HC AG+SRS T+ +AYLM+ ++M DAY VK K+ ISPN
Sbjct: 389 EAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPN 448
Query: 334 FNFMGQLLDFERTL 347
NFMGQLL+FE L
Sbjct: 449 LNFMGQLLEFEEDL 462
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 173 bits (439), Expect = 2e-43
Identities = 113/332 (34%), Positives = 176/332 (53%), Gaps = 49/332 (14%)
Query: 27 LELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRF 86
LE G E++LL+D RP Y +SHI AIN+ +M RRLQ+ + + L + +
Sbjct: 19 LESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSA-KHKV 77
Query: 87 TRRCGTDTVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLH 146
C + VV+YD+SS D + + L +LL KL+ L GGF++F F
Sbjct: 78 DIDC-SQKVVVYDQSSQDV-ASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGL 135
Query: 147 CE--TNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQP 204
CE + L +C S P LPV +G
Sbjct: 136 CEGKSTLVPTCISQ-PCLPVANIG------------------------------------ 158
Query: 205 SFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHW 264
P ILP LYLGC +D N +++++ GI Y+LN + P + E + ++P++D +
Sbjct: 159 --PTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKP-DFIPESHFLRVPVNDSF 215
Query: 265 SQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVK 324
+ + + +++ FI++A+ N VLVHCLAGISRS T+ +AY+M+++++S+++AY VK
Sbjct: 216 CEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVK 275
Query: 325 MKKSNISPNFNFMGQLLDFERTL----GLSSP 352
K+ ISPNFNF+GQLLD+E+ + G S P
Sbjct: 276 EKRPTISPNFNFLGQLLDYEKKIKNQTGASGP 307
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 169 bits (428), Expect = 4e-42
Identities = 118/349 (33%), Positives = 183/349 (52%), Gaps = 34/349 (9%)
Query: 33 RLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGT 92
+ LL+DCRP + + +I ++NV I+ RR KG++ + + E+ R
Sbjct: 44 KCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRA-KGSVSLEQILPAEEEVRARLRSGLY 102
Query: 93 DTVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRA--FYLEGGFSKFQAEFSLHCETN 150
V++YDE S E+ +S + L+++ L+ R L+GG+ +F +E+ C
Sbjct: 103 SAVIVYDERSPR-AESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKT 161
Query: 151 LDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEI 210
+ ++ PP+P L + S G+PL + PVEI
Sbjct: 162 K--ALAAIPPPVPPSATEPLDLGCSSC------------------GTPLHDQ--GGPVEI 199
Query: 211 LPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQ 270
LPFLYLG A + D+L+ GI +LNV+ + PN FE G ++YK IP+ D+ ++S
Sbjct: 200 LPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFE--GHYQYKCIPVEDNHKADISS 257
Query: 271 FFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNI 330
+F EAI +ID + VLVHC AGISRS T+ +AYLM K + + +A++ VK ++S I
Sbjct: 258 WFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSII 317
Query: 331 SPNFNFMGQLLDFE-RTLGLSSPCDNRVPAQQLYF-----TTPSNQNVY 373
SPNF+FMGQLL FE + L S + P+ L TP++Q V+
Sbjct: 318 SPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVF 366
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 166 bits (420), Expect = 3e-41
Identities = 107/310 (34%), Positives = 157/310 (50%), Gaps = 25/310 (8%)
Query: 35 LLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDT 94
LL+DCR + + HI ++NV I+ RR KG + + + E R R
Sbjct: 25 LLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRA-KGAMGLEHIVPNAELRGRLLAGAYHAV 83
Query: 95 VVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGS 154
V+L + S++ G L + + F+L+GG+ F A +
Sbjct: 84 VLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSA--------SCPEL 135
Query: 155 CSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFL 214
CS S P+ + L +S+ ES D G PVEILPFL
Sbjct: 136 CSKQSTPMGL----SLPLSTSVPDSAESGCSSCSTPLYDQGG----------PVEILPFL 181
Query: 215 YLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPE 274
YLG A ++ D+L+ GI ++NV+ N PN FE G ++YK IP+ D+ ++S +F E
Sbjct: 182 YLGSAYHASRKDMLDALGITALINVSANCPNHFE--GHYQYKSIPVEDNHKADISSWFNE 239
Query: 275 AISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNF 334
AI FID + V VHC AGISRS T+ +AYLM+ + +++A++ VK ++S ISPNF
Sbjct: 240 AIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNF 299
Query: 335 NFMGQLLDFE 344
+FMGQLL FE
Sbjct: 300 SFMGQLLQFE 309
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 162 bits (411), Expect = 4e-40
Identities = 109/323 (33%), Positives = 167/323 (51%), Gaps = 56/323 (17%)
Query: 35 LLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDT 94
L++D R Y S H+ S++N+ ++ RRLQ+G + + L
Sbjct: 28 LVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQ--VEATEPQD 85
Query: 95 VVLYDESSSDWNENTGGESVLGLLLKKLKDEGC--RAFYLEGGFSKFQAEFSLHCETNLD 152
VV+YD+S+ D + +S L +LL KL +GC L GGF+ F + F CE
Sbjct: 86 VVVYDQSTRDASV-LAADSFLSILLSKL--DGCFDSVAILTGGFATFSSCFPGLCE---- 138
Query: 153 GSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPV---- 208
P +L P+S SQP PV
Sbjct: 139 ------GKPAALL--------------------------------PMSLSQPCLPVPSVG 160
Query: 209 --EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQ 266
ILP LYLG KD N D++ + GI Y+LN + + P + E ++ ++PI+D++ +
Sbjct: 161 LTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKP-DFICESRFMRVPINDNYCE 219
Query: 267 NLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMK 326
L + ++I FID+A+ +C V+VHCLAGISRS T+ +AY+M+ + +S +DAY VK +
Sbjct: 220 KLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDR 279
Query: 327 KSNISPNFNFMGQLLDFERTLGL 349
+ +ISPNFNF+GQLL++ER+L L
Sbjct: 280 RPSISPNFNFLGQLLEYERSLKL 302
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 157 bits (398), Expect = 1e-38
Identities = 116/319 (36%), Positives = 160/319 (50%), Gaps = 41/319 (12%)
Query: 32 ERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTR--R 89
ER LL+DCRP + H+ +A V ++ RR + P L DR TR R
Sbjct: 25 ERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRAR--GPPAAVLACLLPDRALRTRLVR 82
Query: 90 CGTDTVVLYDESSSDWNE---NTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLH 146
V+ DE S+ E ++ +L LL + + ++L GGF FQ
Sbjct: 83 GELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGFQG----- 137
Query: 147 CETNLDGSCSSS-SPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPS 205
C +L CS + +P LP G D S +DS P
Sbjct: 138 CCPDL---CSEAPAPALPPTG--------------------DKTSRSDSRAPVYDQGGP- 173
Query: 206 FPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWS 265
VEILP+L+LG S++L L+ GI +LNV+ + PN FE G F+YK IP+ D+
Sbjct: 174 --VEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFE--GLFRYKSIPVEDNQM 229
Query: 266 QNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKM 325
+S +F EAI FID + VLVHC AGISRS T+ +AYLMQ + +++A+D VK
Sbjct: 230 VEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQ 289
Query: 326 KKSNISPNFNFMGQLLDFE 344
++ ISPNF+FMGQLL FE
Sbjct: 290 RRGVISPNFSFMGQLLQFE 308
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 156 bits (394), Expect = 3e-38
Identities = 109/331 (32%), Positives = 164/331 (49%), Gaps = 41/331 (12%)
Query: 33 RLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCG- 91
R +++DCRP + +S++ ++NV + ++LRR + G + R + R R + G
Sbjct: 22 RCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLPDEAARARLLQEGGG 81
Query: 92 -TDTVVLYDESSSDWN---ENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHC 147
VV+ D+ S W E + VL LL L G R ++L+GG+ F +E+ C
Sbjct: 82 GVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLP-AGPRVYFLKGGYETFYSEYPECC 140
Query: 148 ETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNS--QPS 205
+ + S IES+ + G P+ N +P+
Sbjct: 141 ----------------------VDVKPISQEKIESE-----RALISQCGKPVVNVSYRPA 173
Query: 206 F----PVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPIS 261
+ PVEILPFLYLG A ++ + L I +LNV+ A YK IP+
Sbjct: 174 YDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEAC--ATHLHYKWIPVE 231
Query: 262 DHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYD 321
D + ++S F EAI FID R K VLVHC AGISRS T+ +AYLM+ + +A+D
Sbjct: 232 DSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFD 291
Query: 322 IVKMKKSNISPNFNFMGQLLDFERTLGLSSP 352
+K ++S +SPNF FMGQLL +E + S+P
Sbjct: 292 YIKQRRSMVSPNFGFMGQLLQYESEILPSTP 322
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 144 bits (364), Expect = 1e-34
Identities = 92/253 (36%), Positives = 135/253 (53%), Gaps = 30/253 (11%)
Query: 127 CRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDR 186
C +GG+ +F +E+ C + ++ PP+P L + S
Sbjct: 47 CLCSESQGGYERFSSEYPEFCSKTK--ALAAIPPPVPPSATEPLDLGCSSC--------- 95
Query: 187 DPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNL 246
G+PL + PVEILPFLYLG A + D+L+ GI +LNV+ + PN
Sbjct: 96 ---------GTPLHDQ--GGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNH 144
Query: 247 FENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVA 306
FE G ++YK IP+ D+ ++S +F EAI +ID + VLVHC AGISRS T+ +A
Sbjct: 145 FE--GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLA 202
Query: 307 YLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFE-RTLGLSSPCDNRVPAQQLYF- 364
YLM K + + +A++ VK ++S ISPNF+FMGQLL FE + L S + P+ L
Sbjct: 203 YLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRER 262
Query: 365 ----TTPSNQNVY 373
TP++Q V+
Sbjct: 263 GKTPATPTSQFVF 275
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 123 bits (308), Expect = 3e-28
Identities = 59/120 (49%), Positives = 79/120 (65%)
Query: 228 LEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNC 287
++ I Y++NVT +LP G F YK++P +D QNL Q+F EA FI+EA
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 288 GVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTL 347
G+L+HC AG+SRS T+ +AYLM+ ++M DAY VK K+ ISPN NFMGQLL+FE L
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 123 bits (308), Expect = 3e-28
Identities = 59/120 (49%), Positives = 79/120 (65%)
Query: 228 LEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNC 287
++ I Y++NVT +LP G F YK++P +D QNL Q+F EA FI+EA
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 288 GVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTL 347
G+L+HC AG+SRS T+ +AYLM+ ++M DAY VK K+ ISPN NFMGQLL+FE L
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 100 bits (250), Expect = 2e-21
Identities = 64/192 (33%), Positives = 98/192 (51%), Gaps = 8/192 (4%)
Query: 176 SSSDIESDLDRDPNSATDSDGSPLSNS------QPSFPVEILPFLYLGCAKDSTNLDVLE 229
+S +I ++L++ N + N Q P I LYLG +++NL+ L+
Sbjct: 272 TSKEIRNELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQ 331
Query: 230 EFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGV 289
G+ YILNVT + N F G F Y I + D + +L + EA FI++A+ +
Sbjct: 332 GSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKC 389
Query: 290 LVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGL 349
LVHC G+SRS + +AY M++ + AY+ VK K+S PN FM QL ++E L
Sbjct: 390 LVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDA 449
Query: 350 SSPCDNRVPAQQ 361
S N++ QQ
Sbjct: 450 SKQRHNKLWRQQ 461
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 100 bits (250), Expect = 2e-21
Identities = 64/192 (33%), Positives = 98/192 (51%), Gaps = 8/192 (4%)
Query: 176 SSSDIESDLDRDPNSATDSDGSPLSNS------QPSFPVEILPFLYLGCAKDSTNLDVLE 229
+S +I ++L++ N + N Q P I LYLG +++NL+ L+
Sbjct: 283 TSKEIRNELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQ 342
Query: 230 EFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGV 289
G+ YILNVT + N F G F Y I + D + +L + EA FI++A+ +
Sbjct: 343 GSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKC 400
Query: 290 LVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGL 349
LVHC G+SRS + +AY M++ + AY+ VK K+S PN FM QL ++E L
Sbjct: 401 LVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDA 460
Query: 350 SSPCDNRVPAQQ 361
S N++ QQ
Sbjct: 461 SKQRHNKLWRQQ 472
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 100 bits (250), Expect = 2e-21
Identities = 64/192 (33%), Positives = 98/192 (51%), Gaps = 8/192 (4%)
Query: 176 SSSDIESDLDRDPNSATDSDGSPLSNS------QPSFPVEILPFLYLGCAKDSTNLDVLE 229
+S +I ++L++ N + N Q P I LYLG +++NL+ L+
Sbjct: 272 TSKEIRNELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQ 331
Query: 230 EFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGV 289
G+ YILNVT + N F G F Y I + D + +L + EA FI++A+ +
Sbjct: 332 GSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKC 389
Query: 290 LVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGL 349
LVHC G+SRS + +AY M++ + AY+ VK K+S PN FM QL ++E L
Sbjct: 390 LVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDA 449
Query: 350 SSPCDNRVPAQQ 361
S N++ QQ
Sbjct: 450 SKQRHNKLWRQQ 461
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 97.1 bits (240), Expect = 2e-20
Identities = 55/137 (40%), Positives = 81/137 (59%), Gaps = 3/137 (2%)
Query: 209 EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNL 268
+ILP LY+G KD+ + + L + + +IL+V + + E KY IP +D SQNL
Sbjct: 7 KILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGV---KYLCIPAADSPSQNL 63
Query: 269 SQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKS 328
++ F E+I FI E R + LVHCLAG+SRSVT+ +AY+M + DA V+ +S
Sbjct: 64 TRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRS 123
Query: 329 NISPNFNFMGQLLDFER 345
+PN F QL +FE+
Sbjct: 124 CANPNVGFQRQLQEFEK 140
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 95.5 bits (236), Expect = 7e-20
Identities = 51/155 (32%), Positives = 88/155 (56%), Gaps = 2/155 (1%)
Query: 203 QPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISD 262
Q P +I ++LG +++NL+ L+ G++YILNVT + N F G F+Y I + D
Sbjct: 304 QMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFP--GVFEYHNIRVYD 361
Query: 263 HWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDI 322
+ +L ++ + FI +A+ LVHC G+SRS + +AY M++ +++ AYD
Sbjct: 362 EEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDY 421
Query: 323 VKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRV 357
VK +++ PN +FM QL +++ L S N++
Sbjct: 422 VKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKL 456
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 94.7 bits (234), Expect = 1e-19
Identities = 54/145 (37%), Positives = 80/145 (55%), Gaps = 3/145 (2%)
Query: 210 ILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLS 269
I P+L LG + +LD L++ + +ILNV + N F +F YK I I D N+
Sbjct: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAF--LSDFTYKSISILDLPETNIL 126
Query: 270 QFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSN 329
+FPE FI+EA+ K+ VLVHC AG+SR+ + + +LM S A+ +VK + +
Sbjct: 127 SYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPS 186
Query: 330 ISPNFNFMGQLLDFERTLGLSSPCD 354
I PN FM QL ++ S+ CD
Sbjct: 187 ICPNSGFMEQLRTYQEGKE-SNKCD 210
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 90.1 bits (222), Expect = 3e-18
Identities = 50/139 (35%), Positives = 79/139 (56%), Gaps = 2/139 (1%)
Query: 209 EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNL 268
+I L+LG ++N +L+ GI I+N T +PN N +F+Y ++P++D +
Sbjct: 29 QITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNF--NWPQFEYVKVPLADMPHAPI 86
Query: 269 SQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKS 328
+F I K+ LVHC AG+SRS T+ +AYLM+ N+ + +AY+ VK ++
Sbjct: 87 GLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 146
Query: 329 NISPNFNFMGQLLDFERTL 347
I PN F QL+D+ER L
Sbjct: 147 VIRPNVGFWRQLIDYERQL 165
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 80.1 bits (196), Expect = 3e-15
Identities = 57/156 (36%), Positives = 79/156 (50%), Gaps = 11/156 (7%)
Query: 194 SDGSPLSNSQPSFPV-EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGE 252
SDGS S PS P E+ P +Y+G A + ++ L++ GI ++LN + N
Sbjct: 17 SDGSGCY-SLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNA 75
Query: 253 FKYKQ-------IPISDHWSQNLSQFFPEAISFIDEARG-KNCGVLVHCLAGISRSVTVT 304
YK I +D NLS +F A FID+A KN VLVHC G SRS T+
Sbjct: 76 NFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLV 135
Query: 305 VAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340
+AYLM + + + A IV+ + I PN F+ QL
Sbjct: 136 IAYLMMRQKMDVKSALSIVRQNR-EIGPNDGFLAQL 170
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 78.6 bits (192), Expect = 9e-15
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 5/141 (3%)
Query: 209 EILPFLYLGCAKDS--TNLDVLEEFGIKYILNVTPNLPNLFENAGE---FKYKQIPISDH 263
EILP L+LG + + L VL++ GI +I+ + N+ F F+Y + I+D+
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 264 WSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIV 323
+N+ +FFP FID + VLVH AGISRS +AY+M+ + DA+ V
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 324 KMKKSNISPNFNFMGQLLDFE 344
+ ++ I+PN F+ QL ++E
Sbjct: 151 QERRFCINPNAGFVHQLQEYE 171
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 78.6 bits (192), Expect = 9e-15
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 5/141 (3%)
Query: 209 EILPFLYLGCAKDS--TNLDVLEEFGIKYILNVTPNLPNLFENAGE---FKYKQIPISDH 263
EILP L+LG + + L VL++ GI +I+ + N+ F F+Y + I+D+
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 264 WSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIV 323
+N+ +FFP FID + VLVH AGISRS +AY+M+ + DA+ V
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 324 KMKKSNISPNFNFMGQLLDFE 344
+ ++ I+PN F+ QL ++E
Sbjct: 151 QERRFCINPNAGFVHQLQEYE 171
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 78.6 bits (192), Expect = 9e-15
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 5/141 (3%)
Query: 209 EILPFLYLGCAKDS--TNLDVLEEFGIKYILNVTPNLPNLFENAGE---FKYKQIPISDH 263
EILP L+LG + + L VL++ GI +I+ + N+ F F+Y + I+D+
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 264 WSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIV 323
+N+ +FFP FID + VLVH AGISRS +AY+M+ + DA+ V
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 324 KMKKSNISPNFNFMGQLLDFE 344
+ ++ I+PN F+ QL ++E
Sbjct: 151 QERRFCINPNAGFVHQLQEYE 171
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 76.3 bits (186), Expect = 4e-14
Identities = 49/137 (35%), Positives = 73/137 (53%), Gaps = 7/137 (5%)
Query: 209 EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNL 268
++LP LYLG D+ +LD L I +I+++ + L + + Y +IP++D +
Sbjct: 7 KVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQ---DITYLRIPVADTPEVPI 63
Query: 269 SQFFPEAISFIDEAR--GKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMK 326
+ F E I+FI R G NC LVHC AGISRS T+ AY+M L D + +K
Sbjct: 64 KKHFKECINFIHCCRLNGGNC--LVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKAT 121
Query: 327 KSNISPNFNFMGQLLDF 343
+ +PN F QL +F
Sbjct: 122 RPIANPNPGFRQQLEEF 138
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 73.6 bits (179), Expect = 3e-13
Identities = 45/141 (31%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Query: 210 ILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLS 269
I P LYLG ++ NL+ L+ + +ILN+ + N + F Y + + D S L
Sbjct: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPE--RFTYHNVRLWDEESAQLL 389
Query: 270 QFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSN 329
+ E FI+ AR + VLVHC G+SRS +AY M++ S+ A V+ +
Sbjct: 390 PHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPI 449
Query: 330 ISPNFNFMGQLLDFERTLGLS 350
PN F+ QL ++ L S
Sbjct: 450 ARPNPGFLRQLQIYQGILTAS 470
>gi|6005956 dual specificity phosphatase 12 [Homo sapiens]
Length = 340
Score = 69.3 bits (168), Expect = 5e-12
Identities = 51/155 (32%), Positives = 70/155 (45%), Gaps = 8/155 (5%)
Query: 194 SDGSPLSNSQPSFP------VEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLF 247
SDG LSN S +E+ P LY G A D L E GI +L V P+
Sbjct: 8 SDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFK 67
Query: 248 ENAG--EFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTV 305
G + +P D +L ++FI +AR + VLVHC AG+SRSV +
Sbjct: 68 AGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIIT 127
Query: 306 AYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340
A+LM+ L AY+ +++ K N F QL
Sbjct: 128 AFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQL 162
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 69.3 bits (168), Expect = 5e-12
Identities = 47/150 (31%), Positives = 74/150 (49%), Gaps = 6/150 (4%)
Query: 198 PLSNSQPSFP--VEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPN-LFENAGEFK 254
P+ QPS +I LY+ + N +L I ++NV+ + N L+E + +
Sbjct: 9 PVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYE---DIQ 65
Query: 255 YKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNL 314
Y Q+P++D + L FF I K L+HC AG+SRS + +AYLM+ +
Sbjct: 66 YMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAM 125
Query: 315 SMNDAYDIVKMKKSNISPNFNFMGQLLDFE 344
S+ DA+ K + I PN F QL+ +E
Sbjct: 126 SLLDAHTWTKSCRPIIRPNSGFWEQLIHYE 155
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 68.9 bits (167), Expect = 7e-12
Identities = 50/144 (34%), Positives = 74/144 (51%), Gaps = 7/144 (4%)
Query: 209 EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPN----LPNLFENAGEFKYKQIPISDHW 264
E+ P LYLG + N L GI ++LN + + P +E G +Y + D
Sbjct: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLG-IRYLGVEAHDSP 122
Query: 265 SQNLSQFFPEAISFIDEARGKNCG-VLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIV 323
+ ++S F A FI A + G +LVHC G+SRS T+ +AYLM +L++ +A V
Sbjct: 123 AFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKV 182
Query: 324 KMKKSNISPNFNFMGQLLDFERTL 347
K + I PN F+ QLL +R L
Sbjct: 183 KDHR-GIIPNRGFLRQLLALDRRL 205
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,595,085
Number of Sequences: 37866
Number of extensions: 663534
Number of successful extensions: 2014
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1756
Number of HSP's gapped (non-prelim): 224
length of query: 381
length of database: 18,247,518
effective HSP length: 104
effective length of query: 277
effective length of database: 14,309,454
effective search space: 3963718758
effective search space used: 3963718758
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.