Search of human proteins with 41352697

Search of human proteins with 41352697

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41352697 centromere protein I [Homo sapiens]
         (756 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41352697 centromere protein I [Homo sapiens]                      1540   0.0  
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid...    34   0.44 
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide...    34   0.44 
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated...    34   0.44 
gi|66932984 folylpolyglutamate synthase isoform a precursor [Hom...    32   2.2  
gi|169217518 PREDICTED: FSHD region gene 2-like [Homo sapiens]         32   2.2  
gi|169218236 PREDICTED: FSHD region gene 2-like [Homo sapiens]         32   2.2  
gi|185136049 FSHD region gene 2 family, member C [Homo sapiens]        32   2.2  
gi|144953907 major facilitator superfamily domain containing 6 [...    30   6.3  
gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13...    30   8.3  
gi|118572588 cyclin F [Homo sapiens]                                   30   8.3  

>gi|41352697 centromere protein I [Homo sapiens]
          Length = 756

 Score = 1540 bits (3986), Expect = 0.0
 Identities = 756/756 (100%), Positives = 756/756 (100%)

Query: 1   MSPQKRVKNVQAQNRTSQGSSSFQTTLSAWKVKQDPSNSKNISKHGQNNPVGDYEHADDQ 60
           MSPQKRVKNVQAQNRTSQGSSSFQTTLSAWKVKQDPSNSKNISKHGQNNPVGDYEHADDQ
Sbjct: 1   MSPQKRVKNVQAQNRTSQGSSSFQTTLSAWKVKQDPSNSKNISKHGQNNPVGDYEHADDQ 60

Query: 61  AEEDALQMAVGYFEKGPIKASQNKDKTLEKHLKTVENVAWKNGLASEEIDILLNIALSGK 120
           AEEDALQMAVGYFEKGPIKASQNKDKTLEKHLKTVENVAWKNGLASEEIDILLNIALSGK
Sbjct: 61  AEEDALQMAVGYFEKGPIKASQNKDKTLEKHLKTVENVAWKNGLASEEIDILLNIALSGK 120

Query: 121 FGNAVNTRILKCMIPATVISEDSVVKAVSWLCVGKCSGSTKVLFYRWLVAMFDFIDRKEQ 180
           FGNAVNTRILKCMIPATVISEDSVVKAVSWLCVGKCSGSTKVLFYRWLVAMFDFIDRKEQ
Sbjct: 121 FGNAVNTRILKCMIPATVISEDSVVKAVSWLCVGKCSGSTKVLFYRWLVAMFDFIDRKEQ 180

Query: 181 INLLYGFFFASLQDDALCPYVCHLLYLLTKKENVKPFRVRKLLDLQAKMGMQPHLQALLS 240
           INLLYGFFFASLQDDALCPYVCHLLYLLTKKENVKPFRVRKLLDLQAKMGMQPHLQALLS
Sbjct: 181 INLLYGFFFASLQDDALCPYVCHLLYLLTKKENVKPFRVRKLLDLQAKMGMQPHLQALLS 240

Query: 241 LYKFFAPALISVSLPVRKKIYFKNSENLWKTALLAVKQRNRGPSPEPLKLMLGPANVRPL 300
           LYKFFAPALISVSLPVRKKIYFKNSENLWKTALLAVKQRNRGPSPEPLKLMLGPANVRPL
Sbjct: 241 LYKFFAPALISVSLPVRKKIYFKNSENLWKTALLAVKQRNRGPSPEPLKLMLGPANVRPL 300

Query: 301 KRKWNSLSVIPVLNSSSYTKECGKKEMSLSDCLNRSGSFPLEQLQSFPQLLQNIHCLELP 360
           KRKWNSLSVIPVLNSSSYTKECGKKEMSLSDCLNRSGSFPLEQLQSFPQLLQNIHCLELP
Sbjct: 301 KRKWNSLSVIPVLNSSSYTKECGKKEMSLSDCLNRSGSFPLEQLQSFPQLLQNIHCLELP 360

Query: 361 SQMGSVLNNSLLLHYINCVRDEPVLLRFYYWLSQTLQEECIWYKVNNYEHGKEFTNFLDT 420
           SQMGSVLNNSLLLHYINCVRDEPVLLRFYYWLSQTLQEECIWYKVNNYEHGKEFTNFLDT
Sbjct: 361 SQMGSVLNNSLLLHYINCVRDEPVLLRFYYWLSQTLQEECIWYKVNNYEHGKEFTNFLDT 420

Query: 421 IIRAECFLQEGFYSCEAFLYKSLPLWDGLCCRSQFLQLVSWIPFSSFSEVKPLLFDHLAQ 480
           IIRAECFLQEGFYSCEAFLYKSLPLWDGLCCRSQFLQLVSWIPFSSFSEVKPLLFDHLAQ
Sbjct: 421 IIRAECFLQEGFYSCEAFLYKSLPLWDGLCCRSQFLQLVSWIPFSSFSEVKPLLFDHLAQ 480

Query: 481 LFFTSTIYFKCSVLQSLKELLQNWLLWLSMDIHMKPVTNSPLETTLGGSMNSVSKLIHYV 540
           LFFTSTIYFKCSVLQSLKELLQNWLLWLSMDIHMKPVTNSPLETTLGGSMNSVSKLIHYV
Sbjct: 481 LFFTSTIYFKCSVLQSLKELLQNWLLWLSMDIHMKPVTNSPLETTLGGSMNSVSKLIHYV 540

Query: 541 GWLSTTAMRLESNNTFLLHFILDFYEKVCDIYINYNLPLVVLFPPGIFYSALLSLDTSIL 600
           GWLSTTAMRLESNNTFLLHFILDFYEKVCDIYINYNLPLVVLFPPGIFYSALLSLDTSIL
Sbjct: 541 GWLSTTAMRLESNNTFLLHFILDFYEKVCDIYINYNLPLVVLFPPGIFYSALLSLDTSIL 600

Query: 601 NQLCFIMHRYRKNLTAAKKNELVQKTKSEFNFSSKTYQEFNHYLTSMVGCLWTSKPFGKG 660
           NQLCFIMHRYRKNLTAAKKNELVQKTKSEFNFSSKTYQEFNHYLTSMVGCLWTSKPFGKG
Sbjct: 601 NQLCFIMHRYRKNLTAAKKNELVQKTKSEFNFSSKTYQEFNHYLTSMVGCLWTSKPFGKG 660

Query: 661 IYIDPEILEKTGVAEYKNSLNVVHHPSFLSYAVSFLLQESPEERTVNVSSIRGKKWSWYL 720
           IYIDPEILEKTGVAEYKNSLNVVHHPSFLSYAVSFLLQESPEERTVNVSSIRGKKWSWYL
Sbjct: 661 IYIDPEILEKTGVAEYKNSLNVVHHPSFLSYAVSFLLQESPEERTVNVSSIRGKKWSWYL 720

Query: 721 DYLFSQGLQGLKLFIRSSVHHSSIPRAEGINCNNQY 756
           DYLFSQGLQGLKLFIRSSVHHSSIPRAEGINCNNQY
Sbjct: 721 DYLFSQGLQGLKLFIRSSVHHSSIPRAEGINCNNQY 756


>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
           isoform 2 [Homo sapiens]
          Length = 4097

 Score = 34.3 bits (77), Expect = 0.44
 Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 8/72 (11%)

Query: 80  ASQNKDKTLEKHLKTVENVAWKNGLASEEIDILLNIALSGKFGNAVNTRILKCMIPATVI 139
           A +  +K + KHLK  +N++    ++ EEI I + + + G  G  +N  +L      TV 
Sbjct: 822 AQKGFNKVVLKHLKKTKNLSSNEAISLEEIRIRV-VQMLGSLGGQINKNLL------TVT 874

Query: 140 SEDSVVKA-VSW 150
           S D ++K+ V+W
Sbjct: 875 SSDEMMKSYVAW 886


>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
           isoform 1 [Homo sapiens]
          Length = 4128

 Score = 34.3 bits (77), Expect = 0.44
 Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 8/72 (11%)

Query: 80  ASQNKDKTLEKHLKTVENVAWKNGLASEEIDILLNIALSGKFGNAVNTRILKCMIPATVI 139
           A +  +K + KHLK  +N++    ++ EEI I + + + G  G  +N  +L      TV 
Sbjct: 822 AQKGFNKVVLKHLKKTKNLSSNEAISLEEIRIRV-VQMLGSLGGQINKNLL------TVT 874

Query: 140 SEDSVVKA-VSW 150
           S D ++K+ V+W
Sbjct: 875 SSDEMMKSYVAW 886


>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
           catalytic polypeptide [Homo sapiens]
          Length = 4096

 Score = 34.3 bits (77), Expect = 0.44
 Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 8/72 (11%)

Query: 80  ASQNKDKTLEKHLKTVENVAWKNGLASEEIDILLNIALSGKFGNAVNTRILKCMIPATVI 139
           A +  +K + KHLK  +N++    ++ EEI I + + + G  G  +N  +L      TV 
Sbjct: 822 AQKGFNKVVLKHLKKTKNLSSNEAISLEEIRIRV-VQMLGSLGGQINKNLL------TVT 874

Query: 140 SEDSVVKA-VSW 150
           S D ++K+ V+W
Sbjct: 875 SSDEMMKSYVAW 886


>gi|66932984 folylpolyglutamate synthase isoform a precursor [Homo
           sapiens]
          Length = 587

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 21/108 (19%)

Query: 27  LSAWKVKQDPSNSKNISKHGQNNPVGDYEHADDQAEEDALQMAVGYFEKGPIKASQNKDK 86
           LSAW V Q+PS                 E+ D     + LQ   GY E+  +K  +   +
Sbjct: 32  LSAWPVPQEPS----------------MEYQDAVRMLNTLQTNAGYLEQ--VKRQRGDPQ 73

Query: 87  TLEKHLKTVENVAWKNGLASEEIDILLNIALSGKFGNAVNTRILKCMI 134
           T    L+ +E    ++GL  E++D L  I ++G  G        +C++
Sbjct: 74  T---QLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECIL 118


>gi|169217518 PREDICTED: FSHD region gene 2-like [Homo sapiens]
          Length = 282

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 6/67 (8%)

Query: 278 QRNRGPSPEPLKLMLGPANVRPLKRKWNSLSVIPVLNSSSYTKECGKKEMSLSD-CLNRS 336
           QR  G  P P K      N    K K  + +      SSSY + C K+++S  D C +R+
Sbjct: 57  QRQAGSEPNPNK-----ENSEETKLKAGNSTAGSEPESSSYRENCRKRKISSKDSCQDRA 111

Query: 337 GSFPLEQ 343
           G+ P E+
Sbjct: 112 GNCPEEE 118


>gi|169218236 PREDICTED: FSHD region gene 2-like [Homo sapiens]
          Length = 282

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 6/67 (8%)

Query: 278 QRNRGPSPEPLKLMLGPANVRPLKRKWNSLSVIPVLNSSSYTKECGKKEMSLSD-CLNRS 336
           QR  G  P P K      N    K K  + +      SSSY + C K+++S  D C +R+
Sbjct: 57  QRQAGSEPNPNK-----ENSEETKLKAGNSTAGSEPESSSYRENCRKRKISSKDSCQDRA 111

Query: 337 GSFPLEQ 343
           G+ P E+
Sbjct: 112 GNCPEEE 118


>gi|185136049 FSHD region gene 2 family, member C [Homo sapiens]
          Length = 282

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 6/67 (8%)

Query: 278 QRNRGPSPEPLKLMLGPANVRPLKRKWNSLSVIPVLNSSSYTKECGKKEMSLSD-CLNRS 336
           QR  G  P P K      N    K K  + +      SSSY + C K+++S  D C +R+
Sbjct: 57  QRQAGSDPNPNK-----ENSEETKLKAGNSTAGSEPESSSYQENCRKRKISSKDICQDRA 111

Query: 337 GSFPLEQ 343
           G+ P E+
Sbjct: 112 GNCPEEE 118


>gi|144953907 major facilitator superfamily domain containing 6
           [Homo sapiens]
          Length = 791

 Score = 30.4 bits (67), Expect = 6.3
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%)

Query: 446 WD--GLCCRSQF--LQLVSWIPFSSFSEVKPLLFDHLAQLFFTSTIYFKCSVLQSLKEL 500
           WD   L C  Q+  +  V+W     +  V   L+ HL  L  T+T++  CSVL  + EL
Sbjct: 436 WDLIKLLCSVQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSEL 494


>gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13
            [Homo sapiens]
          Length = 5058

 Score = 30.0 bits (66), Expect = 8.3
 Identities = 46/230 (20%), Positives = 93/230 (40%), Gaps = 31/230 (13%)

Query: 501  LQNWLLWLSMDIHMKPVTNSP-----LETTLGGSM---NSVSKLIHYVGWLSTTAMRLES 552
            L+  ++WL +  H+  ++NS      L+  LG      N ++ ++  V W+      L S
Sbjct: 1391 LKGCIVWLDVINHLYLLSNSSFSQGHLQNILGNFRDIENKMNSILKIVTWVLNIKKPLCS 1450

Query: 553  NNTFLLHFILDFYEKVCDIYINYNLPLVVLFPPGIFYSALLSLDTSILNQLCFIMHRYRK 612
            +N   ++ +  + + V D ++N  L  V        +  LL+L      Q+   ++    
Sbjct: 1451 SNGSHINCVNIYLKDVTD-FLNIVLTTVFEKEKKPKFEILLALLNDSTKQVRMSINNLTT 1509

Query: 613  NLTAAKKNELVQKTK---SEFNFSSKTYQEFNHYLTSMVGCLWTSKPFGKGIYIDPEILE 669
            +   A ++     T+        S +   +F +    ++      +   KGIY +  ILE
Sbjct: 1510 DFDFASQSNWRYFTELILRPIEMSDEIPNQFQNIWLHLITLGKEFQKLVKGIYFN--ILE 1567

Query: 670  KTGVAEYKNSLNVV-----------------HHPSFLSYAVSFLLQESPE 702
                ++ +N LN+                  H  S+L++++S  LQ SP+
Sbjct: 1568 NNSSSKTENLLNIFATSPKEKDVNSVGNSIYHLASYLAFSLSHDLQNSPK 1617


>gi|118572588 cyclin F [Homo sapiens]
          Length = 786

 Score = 30.0 bits (66), Expect = 8.3
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 192 LQDDALCPYVCHLLYLLTKKENVKPFRVRKLLDLQAKM---GMQPHLQALLSLYKFFAPA 248
           L+   LC ++C L  L T      P R+     L A++     QP    L  L  F    
Sbjct: 425 LRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYED 484

Query: 249 LISVSLPVRKKIYFKNS-ENLWKTALLAVKQR 279
           LI   L + KK +  ++ ++  + +L AVKQR
Sbjct: 485 LIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQR 516


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,564,818
Number of Sequences: 37866
Number of extensions: 1258141
Number of successful extensions: 2826
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2816
Number of HSP's gapped (non-prelim): 19
length of query: 756
length of database: 18,247,518
effective HSP length: 110
effective length of query: 646
effective length of database: 14,082,258
effective search space: 9097138668
effective search space used: 9097138668
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.