Search of human proteins with 41350333

Search of human proteins with 41350333

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41350333 beta-tubulin cofactor D [Homo sapiens]
         (1192 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41350333 beta-tubulin cofactor D [Homo sapiens]                   2371   0.0  
gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]         34   0.73 
gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]        34   0.73 
gi|148806872 lupus brain antigen 1 [Homo sapiens]                      32   2.8  
gi|57863271 hypothetical protein LOC23078 isoform a [Homo sapiens]     32   4.7  
gi|57863273 hypothetical protein LOC23078 isoform b [Homo sapiens]     32   4.7  
gi|19923142 karyopherin beta 1 [Homo sapiens]                          31   6.1  

>gi|41350333 beta-tubulin cofactor D [Homo sapiens]
          Length = 1192

 Score = 2371 bits (6145), Expect = 0.0
 Identities = 1192/1192 (100%), Positives = 1192/1192 (100%)

Query: 1    MALSDEPAAGGPEEEAEDETLAFGAALEAFGESAETRALLGRLREVHGGGAEREVALERF 60
            MALSDEPAAGGPEEEAEDETLAFGAALEAFGESAETRALLGRLREVHGGGAEREVALERF
Sbjct: 1    MALSDEPAAGGPEEEAEDETLAFGAALEAFGESAETRALLGRLREVHGGGAEREVALERF 60

Query: 61   RVIMDKYQEQPHLLDPHLEWMMNLLLDIVQDQTSPASLVHLAFKFLYIITKVRGYKTFLR 120
            RVIMDKYQEQPHLLDPHLEWMMNLLLDIVQDQTSPASLVHLAFKFLYIITKVRGYKTFLR
Sbjct: 61   RVIMDKYQEQPHLLDPHLEWMMNLLLDIVQDQTSPASLVHLAFKFLYIITKVRGYKTFLR 120

Query: 121  LFPHEVADVEPVLDLVTIQNPKDHEAWETRYMLLLWLSVTCLIPFDFSRLDGNLLTQPGQ 180
            LFPHEVADVEPVLDLVTIQNPKDHEAWETRYMLLLWLSVTCLIPFDFSRLDGNLLTQPGQ
Sbjct: 121  LFPHEVADVEPVLDLVTIQNPKDHEAWETRYMLLLWLSVTCLIPFDFSRLDGNLLTQPGQ 180

Query: 181  ARMSIMDRILQIAESYLIVSDKARDAAAVLVSRFITRPDVKQSKMAEFLDWSLCNLARSS 240
            ARMSIMDRILQIAESYLIVSDKARDAAAVLVSRFITRPDVKQSKMAEFLDWSLCNLARSS
Sbjct: 181  ARMSIMDRILQIAESYLIVSDKARDAAAVLVSRFITRPDVKQSKMAEFLDWSLCNLARSS 240

Query: 241  FQTMQGVITMDGTLQALAQIFKHGKREDCLPYAATVLRCLDGCRLPESNQTLLRKLGVKL 300
            FQTMQGVITMDGTLQALAQIFKHGKREDCLPYAATVLRCLDGCRLPESNQTLLRKLGVKL
Sbjct: 241  FQTMQGVITMDGTLQALAQIFKHGKREDCLPYAATVLRCLDGCRLPESNQTLLRKLGVKL 300

Query: 301  VQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQGQSEQKPLILTEDDDEDDDVPEGVER 360
            VQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQGQSEQKPLILTEDDDEDDDVPEGVER
Sbjct: 301  VQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQGQSEQKPLILTEDDDEDDDVPEGVER 360

Query: 361  VIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGC 420
            VIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGC
Sbjct: 361  VIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGC 420

Query: 421  LALAELGRRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEP 480
            LALAELGRRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEP
Sbjct: 421  LALAELGRRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEP 480

Query: 481  QELKPFVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVG 540
            QELKPFVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVG
Sbjct: 481  QELKPFVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVG 540

Query: 541  NRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSAT 600
            NRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSAT
Sbjct: 541  NRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSAT 600

Query: 601  QVFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQ 660
            QVFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQ
Sbjct: 601  QVFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQ 660

Query: 661  QLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSH 720
            QLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSH
Sbjct: 661  QLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSH 720

Query: 721  SRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALG 780
            SRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALG
Sbjct: 721  SRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALG 780

Query: 781  ALPGFLLKGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAV 840
            ALPGFLLKGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAV
Sbjct: 781  ALPGFLLKGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAV 840

Query: 841  CGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARSQPELIEAHTCE 900
            CGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARSQPELIEAHTCE
Sbjct: 841  CGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARSQPELIEAHTCE 900

Query: 901  RIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWS 960
            RIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWS
Sbjct: 901  RIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWS 960

Query: 961  APSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALG 1020
            APSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALG
Sbjct: 961  APSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALG 1020

Query: 1021 SFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIK 1080
            SFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIK
Sbjct: 1021 SFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIK 1080

Query: 1081 NSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYS 1140
            NSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYS
Sbjct: 1081 NSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYS 1140

Query: 1141 DVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQPGAC 1192
            DVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQPGAC
Sbjct: 1141 DVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQPGAC 1192


>gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]
          Length = 509

 Score = 34.3 bits (77), Expect = 0.73
 Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 8/80 (10%)

Query: 558 EYTQPMIDH----LVTMKISHWDGVIRELAARALHNLAQQAPEFSATQV----FPRLLSM 609
           E +Q ++D     L+ + I   +  ++ +AA AL ++A+ +PE + T V       L  M
Sbjct: 158 ELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQM 217

Query: 610 TLSPDLHMRHGSILACAEVA 629
            L+PD  ++H  + A ++V+
Sbjct: 218 ILNPDAKLKHQILSALSQVS 237


>gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]
          Length = 458

 Score = 34.3 bits (77), Expect = 0.73
 Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 8/80 (10%)

Query: 558 EYTQPMIDH----LVTMKISHWDGVIRELAARALHNLAQQAPEFSATQV----FPRLLSM 609
           E +Q ++D     L+ + I   +  ++ +AA AL ++A+ +PE + T V       L  M
Sbjct: 158 ELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQM 217

Query: 610 TLSPDLHMRHGSILACAEVA 629
            L+PD  ++H  + A ++V+
Sbjct: 218 ILNPDAKLKHQILSALSQVS 237


>gi|148806872 lupus brain antigen 1 [Homo sapiens]
          Length = 2375

 Score = 32.3 bits (72), Expect = 2.8
 Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 7/101 (6%)

Query: 954  VASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQ 1013
            V    + A SQ      ++LGL      +LL LV +L  +T +  +   +S FE+    Q
Sbjct: 1468 VVEALYEAASQCEAEPEKILGLAPGGLEILLSLVRALKRVTNNAEKEMVKSCFEFFGISQ 1527

Query: 1014 SDP---QALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVL 1051
             D    Q   +  G +L+I  D  LN R      KT DH L
Sbjct: 1528 VDAKYCQIAQNDPGPILRIIFDLDLNLREK----KTKDHFL 1564


>gi|57863271 hypothetical protein LOC23078 isoform a [Homo sapiens]
          Length = 1905

 Score = 31.6 bits (70), Expect = 4.7
 Identities = 59/267 (22%), Positives = 107/267 (40%), Gaps = 24/267 (8%)

Query: 931  FDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQL-------LGLPTYRYHVL 983
            F +  I ++P + +L+ L+  S  A+V+    SQ     T L       LGLP +    L
Sbjct: 261  FQARDIYYLPFKDQLKLLY--SIGANVSAEKVSQLLSFATTLCSQESSTLGLPDFPLDSL 318

Query: 984  LGLVVSLGGLTESTIRHSTQSLFEY--MKGIQSDPQALGSFSGTLLQIFEDNLLNERVSV 1041
               V  L       I+H+ Q L+ Y  + G +      G      LQ    +LL + + V
Sbjct: 319  AAAVQILDSFPMMPIKHAIQWLYPYSILLGHEGKMAVEGVLKRFELQDSGSSLLPKEI-V 377

Query: 1042 PLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQF 1101
             + K +++ ++     I   +++    V        +   S    + LS   +  EM+Q 
Sbjct: 378  KVEKMMENHVSQASVTIRIADKEVTIKVPAGTRLLSQPCASDRFIQTLSHKQLQAEMMQ- 436

Query: 1102 PGDVRRQALLQLCLL---LCHRFPLIRKTTASQVY--ETLLTYSDVVGADVLDEVVTVLS 1156
                    +  +CL+    C +  + +    +  Y  E ++ Y D+   D+L +  T+ +
Sbjct: 437  -----SHMVKDICLIGGKGCGKTVIAKNFADTLGYNIEPIMLYQDMTARDLLQQRYTLPN 491

Query: 1157 -DTAWDAELAVVREQRNRLCDLLGVPR 1182
             DTAW +   V      +L  L G+ R
Sbjct: 492  GDTAWRSSPLVNAALEGKLVLLDGIHR 518


>gi|57863273 hypothetical protein LOC23078 isoform b [Homo sapiens]
          Length = 1039

 Score = 31.6 bits (70), Expect = 4.7
 Identities = 59/267 (22%), Positives = 107/267 (40%), Gaps = 24/267 (8%)

Query: 931  FDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQL-------LGLPTYRYHVL 983
            F +  I ++P + +L+ L+  S  A+V+    SQ     T L       LGLP +    L
Sbjct: 261  FQARDIYYLPFKDQLKLLY--SIGANVSAEKVSQLLSFATTLCSQESSTLGLPDFPLDSL 318

Query: 984  LGLVVSLGGLTESTIRHSTQSLFEY--MKGIQSDPQALGSFSGTLLQIFEDNLLNERVSV 1041
               V  L       I+H+ Q L+ Y  + G +      G      LQ    +LL + + V
Sbjct: 319  AAAVQILDSFPMMPIKHAIQWLYPYSILLGHEGKMAVEGVLKRFELQDSGSSLLPKEI-V 377

Query: 1042 PLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQF 1101
             + K +++ ++     I   +++    V        +   S    + LS   +  EM+Q 
Sbjct: 378  KVEKMMENHVSQASVTIRIADKEVTIKVPAGTRLLSQPCASDRFIQTLSHKQLQAEMMQ- 436

Query: 1102 PGDVRRQALLQLCLL---LCHRFPLIRKTTASQVY--ETLLTYSDVVGADVLDEVVTVLS 1156
                    +  +CL+    C +  + +    +  Y  E ++ Y D+   D+L +  T+ +
Sbjct: 437  -----SHMVKDICLIGGKGCGKTVIAKNFADTLGYNIEPIMLYQDMTARDLLQQRYTLPN 491

Query: 1157 -DTAWDAELAVVREQRNRLCDLLGVPR 1182
             DTAW +   V      +L  L G+ R
Sbjct: 492  GDTAWRSSPLVNAALEGKLVLLDGIHR 518


>gi|19923142 karyopherin beta 1 [Homo sapiens]
          Length = 876

 Score = 31.2 bits (69), Expect = 6.1
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 19/104 (18%)

Query: 306 LTFLKPKVAA--WRYQRGCRSLAANLQLLTQGQSEQKPLILTEDDDEDDDVPEGVERVIE 363
           L F+K  +    WRY R    +A    L     S+ KPL++               + + 
Sbjct: 368 LPFIKEHIKNPDWRY-RDAAVMAFGCILEGPEPSQLKPLVI---------------QAMP 411

Query: 364 QLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDV-VGSVLDC 406
            L+  +KD   VVR +AA  +GR+   LP A  +DV +  +L C
Sbjct: 412 TLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQC 455


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,654,056
Number of Sequences: 37866
Number of extensions: 1862199
Number of successful extensions: 4623
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 4615
Number of HSP's gapped (non-prelim): 14
length of query: 1192
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1078
effective length of database: 13,930,794
effective search space: 15017395932
effective search space used: 15017395932
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.