Search of human proteins with 40805825

Search of human proteins with 40805825

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40805825 epsilon subunit of coatomer protein complex isoform
b [Homo sapiens]
         (257 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40805825 epsilon subunit of coatomer protein complex isoform ...   512   e-145
gi|31542319 epsilon subunit of coatomer protein complex isoform ...   486   e-138
gi|40805827 epsilon subunit of coatomer protein complex isoform ...   356   1e-98
gi|42794779 myosin 18A isoform b [Homo sapiens]                        31   1.2  
gi|28416946 myosin 18A isoform a [Homo sapiens]                        31   1.2  
gi|5803167 splicing factor 3a, subunit 3 [Homo sapiens]                30   2.7  
gi|89111119 metallothionein-like 5, testis-specific isoform b [H...    29   3.5  
gi|40806200 metallothionein-like 5, testis-specific isoform a [H...    29   3.5  
gi|83415184 transmembrane and tetratricopeptide repeat containin...    29   4.6  
gi|61742823 disrupted in schizophrenia 1 isoform L [Homo sapiens]      28   6.0  
gi|21362074 testes development-related NYD-SP22 isoform 1 [Homo ...    28   7.9  

>gi|40805825 epsilon subunit of coatomer protein complex isoform b
           [Homo sapiens]
          Length = 257

 Score =  512 bits (1318), Expect = e-145
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60
           MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
Sbjct: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60

Query: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRSTAMTVQILLKLDRLDLARKELKR 120
           LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRSTAMTVQILLKLDRLDLARKELKR
Sbjct: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRSTAMTVQILLKLDRLDLARKELKR 120

Query: 121 MQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGR 180
           MQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGR
Sbjct: 121 MQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGR 180

Query: 181 WEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQ 240
           WEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQ
Sbjct: 181 WEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQ 240

Query: 241 AKENDFDRLVLQYAPSA 257
           AKENDFDRLVLQYAPSA
Sbjct: 241 AKENDFDRLVLQYAPSA 257


>gi|31542319 epsilon subunit of coatomer protein complex isoform a
           [Homo sapiens]
          Length = 308

 Score =  486 bits (1251), Expect = e-138
 Identities = 256/308 (83%), Positives = 256/308 (83%), Gaps = 51/308 (16%)

Query: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60
           MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
Sbjct: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60

Query: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRS----------------------- 97
           LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESR                        
Sbjct: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120

Query: 98  ----------------------------TAMTVQILLKLDRLDLARKELKRMQDLDEDAT 129
                                       TAMTVQILLKLDRLDLARKELKRMQDLDEDAT
Sbjct: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180

Query: 130 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 189
           LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ
Sbjct: 181 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 240

Query: 190 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 249
           EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
Sbjct: 241 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 300

Query: 250 VLQYAPSA 257
           VLQYAPSA
Sbjct: 301 VLQYAPSA 308


>gi|40805827 epsilon subunit of coatomer protein complex isoform c
           [Homo sapiens]
          Length = 256

 Score =  356 bits (913), Expect = 1e-98
 Identities = 204/308 (66%), Positives = 204/308 (66%), Gaps = 103/308 (33%)

Query: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60
           MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
Sbjct: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60

Query: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESR------------------------ 96
           LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESR                        
Sbjct: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120

Query: 97  ---------------------------STAMTVQILLKLDRLDLARKELKRMQDLDEDAT 129
                                       TAMTVQILLKLDRLDLARKELKRMQDLDEDAT
Sbjct: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180

Query: 130 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 189
           LTQLATAWVSLAT                                               
Sbjct: 181 LTQLATAWVSLAT----------------------------------------------- 193

Query: 190 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 249
                DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
Sbjct: 194 -----DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 248

Query: 250 VLQYAPSA 257
           VLQYAPSA
Sbjct: 249 VLQYAPSA 256


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 3/129 (2%)

Query: 33   QCINEAQRVKLSSPERDVERDVFLYRAYLAQRKFGVVLDEIKPSSAPELQAVRMFADYLA 92
            Q   EAQR KL   +   E+D+ L  A+  +++      +I   +   +       D  +
Sbjct: 1469 QAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISS 1528

Query: 93   HESRSTAMTVQILLKLDRLDLARKELKRMQDLDEDA-TLTQLATAWVSLATGGEKLQDAY 151
             ES+  A   ++  K    DL  K   + ++LDE A T+  L  A + L    E+++  +
Sbjct: 1529 QESKDEASLAKV--KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTH 1586

Query: 152  YIFQEMADK 160
                E  D+
Sbjct: 1587 SKEMESRDE 1595


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 3/129 (2%)

Query: 33   QCINEAQRVKLSSPERDVERDVFLYRAYLAQRKFGVVLDEIKPSSAPELQAVRMFADYLA 92
            Q   EAQR KL   +   E+D+ L  A+  +++      +I   +   +       D  +
Sbjct: 1469 QAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISS 1528

Query: 93   HESRSTAMTVQILLKLDRLDLARKELKRMQDLDEDA-TLTQLATAWVSLATGGEKLQDAY 151
             ES+  A   ++  K    DL  K   + ++LDE A T+  L  A + L    E+++  +
Sbjct: 1529 QESKDEASLAKV--KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTH 1586

Query: 152  YIFQEMADK 160
                E  D+
Sbjct: 1587 SKEMESRDE 1595


>gi|5803167 splicing factor 3a, subunit 3 [Homo sapiens]
          Length = 501

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 10/92 (10%)

Query: 145 EKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVN 204
           E+L D   + +EM  K S     +N        Q R+    G L++  D   G  +  +N
Sbjct: 16  ERLMDV--MAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDLYDDKDGLRKEELN 73

Query: 205 LIVLSQHLGKPPEVTNRY--LSQLKDAHRSHP 234
            I        P E    Y  L Q+K+ HR HP
Sbjct: 74  AI------SGPNEFAEFYNRLKQIKEFHRKHP 99


>gi|89111119 metallothionein-like 5, testis-specific isoform b [Homo
           sapiens]
          Length = 306

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 34/126 (26%), Positives = 49/126 (38%), Gaps = 24/126 (19%)

Query: 126 EDATLTQL-------ATAWVSLATGGEKLQDAYYIFQEM----ADKCSPTLLLLN----- 169
           EDA +T+L       A+  + L    +  +D +++F+E     AD   P L   N     
Sbjct: 14  EDAMVTELLSPEGPFASENIGLKAPVKYEEDEFHVFKEAYLGPADPKEPVLHAFNPALGA 73

Query: 170 ---GQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQL 226
              GQ    +A G  +  E      L +  G PE      V      +PP     +LS L
Sbjct: 74  DCKGQVKAKLAGGDSDGGE-----LLGEYPGIPELSALEDVALLQAPQPPACNVHFLSSL 128

Query: 227 KDAHRS 232
             AHRS
Sbjct: 129 LPAHRS 134


>gi|40806200 metallothionein-like 5, testis-specific isoform a [Homo
           sapiens]
          Length = 508

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 34/126 (26%), Positives = 49/126 (38%), Gaps = 24/126 (19%)

Query: 126 EDATLTQL-------ATAWVSLATGGEKLQDAYYIFQEM----ADKCSPTLLLLN----- 169
           EDA +T+L       A+  + L    +  +D +++F+E     AD   P L   N     
Sbjct: 14  EDAMVTELLSPEGPFASENIGLKAPVKYEEDEFHVFKEAYLGPADPKEPVLHAFNPALGA 73

Query: 170 ---GQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQL 226
              GQ    +A G  +  E      L +  G PE      V      +PP     +LS L
Sbjct: 74  DCKGQVKAKLAGGDSDGGE-----LLGEYPGIPELSALEDVALLQAPQPPACNVHFLSSL 128

Query: 227 KDAHRS 232
             AHRS
Sbjct: 129 LPAHRS 134


>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
           [Homo sapiens]
          Length = 774

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 3/104 (2%)

Query: 132 QLATAWVSLAT---GGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLL 188
           + A A+ SLA+     E+ ++A  I+Q     C  +  L N      +  G  E A    
Sbjct: 472 EFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHY 531

Query: 189 QEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRS 232
           Q+A+     +   +VNL  L + LG+       Y   L+ AH++
Sbjct: 532 QQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKA 575


>gi|61742823 disrupted in schizophrenia 1 isoform L [Homo sapiens]
          Length = 854

 Score = 28.5 bits (62), Expect = 6.0
 Identities = 28/149 (18%), Positives = 64/149 (42%), Gaps = 10/149 (6%)

Query: 23  KNAFYIGSYQQCINEAQRV---KLSSPERDVERDVFLYRAYLAQRKFGVVLDEIKPSSAP 79
           +N   +GS ++  N  +R    + ++ E  V+ +   Y   L  +        +      
Sbjct: 634 RNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEA 693

Query: 80  ELQAVRMFADYLAHESRSTAMTVQILLKLDRLDLARKELK-RMQDLDEDATLTQLATAWV 138
           +L+A R+    L  +    +++V+   ++D L+ A   +  R+   D+  T  ++   W 
Sbjct: 694 DLEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWK 753

Query: 139 SL------ATGGEKLQDAYYIFQEMADKC 161
           +         GGE+ +++Y +  E+ +KC
Sbjct: 754 THLIPSLHCAGGEQKEESYILSAELGEKC 782


>gi|21362074 testes development-related NYD-SP22 isoform 1 [Homo
           sapiens]
          Length = 262

 Score = 28.1 bits (61), Expect = 7.9
 Identities = 12/25 (48%), Positives = 16/25 (64%)

Query: 142 TGGEKLQDAYYIFQEMADKCSPTLL 166
           +G   L + Y++ QE ADKCSP  L
Sbjct: 78  SGHPYLPEKYWLSQEEADKCSPNYL 102


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,185,671
Number of Sequences: 37866
Number of extensions: 429355
Number of successful extensions: 1354
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1346
Number of HSP's gapped (non-prelim): 12
length of query: 257
length of database: 18,247,518
effective HSP length: 100
effective length of query: 157
effective length of database: 14,460,918
effective search space: 2270364126
effective search space used: 2270364126
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.