Search of human proteins with 40254478

Search of human proteins with 40254478

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40254478 excitatory amino acid transporter 2 [Homo sapiens]
         (574 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40254478 excitatory amino acid transporter 2 [Homo sapiens]       1118   0.0  
gi|169790839 solute carrier family 1 (glial high affinity glutam...   501   e-142
gi|66773030 solute carrier family 1, member 1 [Homo sapiens]          495   e-140
gi|4827012 solute carrier family 1 (high affinity aspartate/glut...   476   e-134
gi|194239697 solute carrier family 1 (glutamate transporter), me...   448   e-126
gi|21314632 solute carrier family 1, member 4 isoform 1 [Homo sa...   392   e-109
gi|5032093 solute carrier family 1 member 5 isoform 1 [Homo sapi...   372   e-103
gi|207444683 solute carrier family 1, member 4 isoform 2 [Homo s...   295   6e-80
gi|223468566 solute carrier family 1 member 5 isoform 3 [Homo sa...   276   3e-74
gi|223468564 solute carrier family 1 member 5 isoform 2 [Homo sa...   273   4e-73
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     32   1.2  
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]                      30   7.9  

>gi|40254478 excitatory amino acid transporter 2 [Homo sapiens]
          Length = 574

 Score = 1118 bits (2891), Expect = 0.0
 Identities = 574/574 (100%), Positives = 574/574 (100%)

Query: 1   MASTEGANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVC 60
           MASTEGANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVC
Sbjct: 1   MASTEGANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVC 60

Query: 61  GGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRA 120
           GGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRA
Sbjct: 61  GGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRA 120

Query: 121 MVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENL 180
           MVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENL
Sbjct: 121 MVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENL 180

Query: 181 VQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGM 240
           VQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGM
Sbjct: 181 VQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGM 240

Query: 241 NVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKI 300
           NVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKI
Sbjct: 241 NVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKI 300

Query: 301 IAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALG 360
           IAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALG
Sbjct: 301 IAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALG 360

Query: 361 TASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVL 420
           TASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVL
Sbjct: 361 TASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVL 420

Query: 421 DGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTS 480
           DGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTS
Sbjct: 421 DGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTS 480

Query: 481 VNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYA 540
           VNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYA
Sbjct: 481 VNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYA 540

Query: 541 AHNSVIVDECKVTLAANGKSADCSVEEEPWKREK 574
           AHNSVIVDECKVTLAANGKSADCSVEEEPWKREK
Sbjct: 541 AHNSVIVDECKVTLAANGKSADCSVEEEPWKREK 574


>gi|169790839 solute carrier family 1 (glial high affinity glutamate
           transporter), member 3 [Homo sapiens]
          Length = 542

 Score =  501 bits (1290), Expect = e-142
 Identities = 269/500 (53%), Positives = 363/500 (72%), Gaps = 12/500 (2%)

Query: 41  LGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISS 100
           L +N  + LTV  VI+G + G  LR     + +V    +FPG++LMRML+ML+LPLIISS
Sbjct: 45  LFRNAFVLLTVTAVIVGTILGFTLRPYRMSYREV-KYFSFPGELLMRMLQMLVLPLIISS 103

Query: 101 LITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKND 160
           L+TG++ LD+KASG++G RA+VYYM+TTIIA V+G+I+V+ IHPG    K+ +    K  
Sbjct: 104 LVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGT-KENMHREGKIV 162

Query: 161 EVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNE--- 217
            V++ DAFLDLIRN+FP NLV+ACF+Q +T  +K     P         AV++ ++E   
Sbjct: 163 RVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAME 222

Query: 218 TVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIV 277
           T+T + EE   V        +G+N LGL+ F + FG  +G M +Q + + +FF+ LNE +
Sbjct: 223 TLTRITEELVPVPGS----VNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAI 278

Query: 278 MKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYF 337
           M+LV +IMWY+P+GI  LI GKI+ ++D+ V+  QL MY VTVI+GL+IH  I LPL+YF
Sbjct: 279 MRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYF 338

Query: 338 VVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATIN 397
           +VTRKNP+ F  G+ QA ITALGT+SS+ TLP+TF+CLEEN G+DKRVTRFVLPVGATIN
Sbjct: 339 LVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATIN 398

Query: 398 MDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAV 457
           MDGTALYEA+AAIFIAQ+N   L+ GQI+T+S+TAT AS+GAA IP AGLVTM+++LT+V
Sbjct: 399 MDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSV 458

Query: 458 GLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQ--HRVHEDIE 515
           GLPT+DI+L++AVDW LDR+RT+ NV+GDS GAGIV HLS+ EL   D +  + V E+ E
Sbjct: 459 GLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENE 518

Query: 516 MTKT-QSIYDDMKNHRESNS 534
           M K  Q I  D +  +  +S
Sbjct: 519 MKKPYQLIAQDNETEKPIDS 538


>gi|66773030 solute carrier family 1, member 1 [Homo sapiens]
          Length = 524

 Score =  495 bits (1274), Expect = e-140
 Identities = 262/471 (55%), Positives = 343/471 (72%), Gaps = 5/471 (1%)

Query: 41  LGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISS 100
           L  N +L  TV  V+LG   G L+R  S +        AFPG+ILMRMLK++ILPLIISS
Sbjct: 15  LKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLIISS 74

Query: 101 LITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKND 160
           +ITG++ LD+  SG++G RA+VYY  TT+IA +LG++LV++I PG  +   ++       
Sbjct: 75  MITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGSTP 134

Query: 161 EVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVT 220
           EVS++DA LDLIRN+FPENLVQACFQQ +T  K+  V PP D E N T    + +  T  
Sbjct: 135 EVSTVDAMLDLIRNMFPENLVQACFQQYKT--KREEVKPPSDPEMNMTEESFTAVMTTAI 192

Query: 221 EVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKL 280
               +TK     G+ + DG+NVLGLI F + FG+ +GKMG++ +++VDFFN L++  MK+
Sbjct: 193 S-KNKTKEYKIVGM-YSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKI 250

Query: 281 VIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVT 340
           V +IM Y PLGI  LI GKII ++D E+  R+LG+YM TV+ GL IH  + LPLIYF+V 
Sbjct: 251 VQIIMCYMPLGILFLIAGKIIEVEDWEIF-RKLGLYMATVLTGLAIHSIVILPLIYFIVV 309

Query: 341 RKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDG 400
           RKNPF F  G+ QA +TAL  +SS+ TLPVTFRC EEN  +DKR+TRFVLPVGATINMDG
Sbjct: 310 RKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDG 369

Query: 401 TALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLP 460
           TALYEAVAA+FIAQ+N + L  GQI+T+S+TAT AS+GAA +P AGLVTM+++L+AVGLP
Sbjct: 370 TALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLP 429

Query: 461 TEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVH 511
            ED++L++AVDWLLDR RT VNV+GD+FG GIV  LSK EL+ +D    V+
Sbjct: 430 AEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVN 480


>gi|4827012 solute carrier family 1 (high affinity
           aspartate/glutamate transporter), member 6 [Homo
           sapiens]
          Length = 564

 Score =  476 bits (1224), Expect = e-134
 Identities = 249/485 (51%), Positives = 345/485 (71%), Gaps = 22/485 (4%)

Query: 41  LGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISS 100
           L +N  + LTV  V++G      LR     +  +    +FPG++LMRML+ML+LPLI+SS
Sbjct: 53  LRRNAFILLTVSAVVIGVSLAFALRPYQLTYRQI-KYFSFPGELLMRMLQMLVLPLIVSS 111

Query: 101 LITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKND 160
           L+TG++ LD KA+GR+G RA VYYM TTIIA  +G+++V  IHPG    K+ L    + +
Sbjct: 112 LVTGMASLDNKATGRMGMRAAVYYMVTTIIAVFIGILMVTIIHPGKGS-KEGLHREGRIE 170

Query: 161 EVSSLDAFLDLIRNLFPENLVQACFQQIQT-----VTKKVLVA-----------PPPDEE 204
            + + DAF+DLIRN+FP NLV+ACF+Q +T     V  + +V            PPP   
Sbjct: 171 TIPTADAFMDLIRNMFPPNLVEACFKQFKTQYSTRVVTRTMVRTENGSEPGASMPPPFSV 230

Query: 205 ANATSAVVSLLNE--TVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQ 262
            N TS + ++     T+ E+    + V   G    +G+N LGL+ F +AFG+ +G M  +
Sbjct: 231 ENGTSFLENVTRALGTLQEMLSFEETVPVPGSA--NGINALGLVVFSVAFGLVIGGMKHK 288

Query: 263 AKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVII 322
            +++ DFF+ LNE +M+LV +I+WY+P+GI  LI GKI+ ++D+ V+  QLGMY +TVI+
Sbjct: 289 GRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIV 348

Query: 323 GLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGID 382
           GL +H GI LPLIYF+VT +NPF F  G+ QA ITA+GT+SS+ TLP+TFRCLEE LG+D
Sbjct: 349 GLFLHAGIVLPLIYFLVTHRNPFPFIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVD 408

Query: 383 KRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASI 442
           +R+TRFVLPVGAT+NMDGTALYEA+AAIFIAQ+N   L+ GQI T+S+TAT ASVGAA I
Sbjct: 409 RRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGI 468

Query: 443 PSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELD 502
           P AGLVTM+++LT+VGLPTEDI+L++AVDW LDR+RT  NV+GDS GA ++ HLS+ EL+
Sbjct: 469 PQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELE 528

Query: 503 TIDSQ 507
             +++
Sbjct: 529 LQEAE 533


>gi|194239697 solute carrier family 1 (glutamate transporter),
           member 7 [Homo sapiens]
          Length = 560

 Score =  448 bits (1153), Expect = e-126
 Identities = 236/471 (50%), Positives = 317/471 (67%), Gaps = 11/471 (2%)

Query: 39  DKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLII 98
           D   +N LL L+V  VI+G + G  LR    + P  +    FPG++LMRMLKM+ILPL++
Sbjct: 12  DVCRRNGLLILSVLSVIVGCLLGFFLRTRR-LSPQEISYFQFPGELLMRMLKMMILPLVV 70

Query: 99  SSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKK 158
           SSL++GL+ LDAK S RLG   + YY+ TT +A ++G+ +V  IHPG+   K+      K
Sbjct: 71  SSLMSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAAQKETTEQSGK 130

Query: 159 NDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPP--PDEEANATSAVVSLLN 216
              +SS DA LDLIRN+FP NLV+A F+Q +T T  V+ +P   P+E       +  +  
Sbjct: 131 -PIMSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPRRILIYGVQE 189

Query: 217 ETVTEVPE-------ETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDF 269
           E  + V           ++V K      DGMNVLG++ F    GI +G+MGD    +V F
Sbjct: 190 ENGSHVQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMGDSGAPLVSF 249

Query: 270 FNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGG 329
              LNE VMK+V + +WY P GI  LI GKI+ + D   V ++LG Y VTV+ GL++HG 
Sbjct: 250 CQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTVVCGLVLHGL 309

Query: 330 IFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFV 389
             LPL+YF +T+KNP  F  GI QA + AL T+SS+ TLP+TF+CL EN  ID+R+ RFV
Sbjct: 310 FILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFV 369

Query: 390 LPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVT 449
           LPVGATINMDGTALYEAVAAIFIAQ+N   LD GQI+T+S+TAT AS+GAA IP AGLVT
Sbjct: 370 LPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVT 429

Query: 450 MLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSE 500
           M+++LT+VGLPT+DI+L++AVDW LDR RT +NV+GD+  AGI+ H+ + +
Sbjct: 430 MVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKD 480


>gi|21314632 solute carrier family 1, member 4 isoform 1 [Homo
           sapiens]
          Length = 532

 Score =  392 bits (1008), Expect = e-109
 Identities = 215/464 (46%), Positives = 300/464 (64%), Gaps = 29/464 (6%)

Query: 41  LGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISS 100
           L +  L+ LTV GV+ GA  G  LR  S     V  L AFPG++L+RML+M+ILPL++ S
Sbjct: 39  LRRQALVLLTVSGVLAGAGLGAALRGLSLSRTQVTYL-AFPGEMLLRMLRMIILPLVVCS 97

Query: 101 LITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQ---LG--- 154
           L++G + LDA   GRLG  A+ Y+  TT+ A+ L V L   I PG+     Q   LG   
Sbjct: 98  LVSGAASLDASCLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGSGAQTLQSSDLGLED 157

Query: 155 PGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSL 214
            G       ++D+FLDL RNLFP NLV A F+   T  K V          N++S     
Sbjct: 158 SGPPPVPKETVDSFLDLARNLFPSNLVVAAFRTYATDYKVVT--------QNSSSG---- 205

Query: 215 LNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILN 274
            N T  ++P  T++         +GMN+LGL+ F +  G+A+ K+G + + ++ FFN LN
Sbjct: 206 -NVTHEKIPIGTEI---------EGMNILGLVLFALVLGVALKKLGSEGEDLIRFFNSLN 255

Query: 275 EIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPL 334
           E  M LV  IMWY P+GI  L+  KI+ +KD+ V+   LG Y+   I+G +IHGGI LPL
Sbjct: 256 EATMVLVSWIMWYVPVGIMFLVGSKIVEMKDIIVLVTSLGKYIFASILGHVIHGGIVLPL 315

Query: 335 IYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGA 394
           IYFV TRKNPF F  G+   + TA  T SS+ TLP   +C+EEN G+DKR++RF+LP+GA
Sbjct: 316 IYFVFTRKNPFRFLLGLLAPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFILPIGA 375

Query: 395 TINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLIL 454
           T+NMDG A+++ VAA+FIAQ+N V L+ GQI T+ +TAT +SVGAA +P+ G++T+ +IL
Sbjct: 376 TVNMDGAAIFQCVAAVFIAQLNNVELNAGQIFTILVTATASSVGAAGVPAGGVLTIAIIL 435

Query: 455 TAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSK 498
            A+GLPT D+ L++AVDW++DR  T VNV GD+ GAGI++HL++
Sbjct: 436 EAIGLPTHDLPLILAVDWIVDRTTTVVNVEGDALGAGILHHLNQ 479


>gi|5032093 solute carrier family 1 member 5 isoform 1 [Homo
           sapiens]
          Length = 541

 Score =  372 bits (955), Expect = e-103
 Identities = 203/465 (43%), Positives = 296/465 (63%), Gaps = 43/465 (9%)

Query: 41  LGKNLLLTLTVFGVILGAV-------CGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLI 93
           L  NLL+ LTV  V+ G          GG L L     P+ +    FPG++L+R+L+M+I
Sbjct: 49  LRANLLVLLTVVAVVAGVALGLGVSGAGGALALG----PERLSAFVFPGELLLRLLRMII 104

Query: 94  LPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPG--NPKLKK 151
           LPL++ SLI G + LD  A GRLG  A+++++ TT++A+ LGV L LA+ PG  +  +  
Sbjct: 105 LPLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINA 164

Query: 152 QLGPGKKNDEVSS---LDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANAT 208
            +G     +   S   LD+FLDL RN+FP NLV A F+   T            EE N T
Sbjct: 165 SVGAAGSAENAPSKEVLDSFLDLARNIFPSNLVSAAFRSYSTTY----------EERNIT 214

Query: 209 SAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVD 268
                            T++ +  G E  +GMN+LGL+ F I FG+A+ K+G + +L++ 
Sbjct: 215 G----------------TRVKVPVGQEV-EGMNILGLVVFAIVFGVALRKLGPEGELLIR 257

Query: 269 FFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHG 328
           FFN  NE  M LV  IMWY+P+GI  L+ GKI+ ++D+ ++  +LG Y++  ++G  IHG
Sbjct: 258 FFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHG 317

Query: 329 GIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRF 388
            + LPLIYF+ TRKNP+ F  GI     TA GT+SS+ TLP+  +C+EEN G+ K ++RF
Sbjct: 318 LLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVAKHISRF 377

Query: 389 VLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLV 448
           +LP+GAT+NMDG AL++ VAA+FIAQ++   LD  +I+T+ +TAT +SVGAA IP+ G++
Sbjct: 378 ILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVL 437

Query: 449 TMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIV 493
           T+ +IL AV LP + ISL++AVDWL+DR  T +NV GD+ GAG++
Sbjct: 438 TLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAGLL 482


>gi|207444683 solute carrier family 1, member 4 isoform 2 [Homo
           sapiens]
          Length = 312

 Score =  295 bits (756), Expect = 6e-80
 Identities = 137/259 (52%), Positives = 193/259 (74%)

Query: 240 MNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGK 299
           MN+LGL+ F +  G+A+ K+G + + ++ FFN LNE  M LV  IMWY P+GI  L+  K
Sbjct: 1   MNILGLVLFALVLGVALKKLGSEGEDLIRFFNSLNEATMVLVSWIMWYVPVGIMFLVGSK 60

Query: 300 IIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITAL 359
           I+ +KD+ V+   LG Y+   I+G +IHGGI LPLIYFV TRKNPF F  G+   + TA 
Sbjct: 61  IVEMKDIIVLVTSLGKYIFASILGHVIHGGIVLPLIYFVFTRKNPFRFLLGLLAPFATAF 120

Query: 360 GTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVV 419
            T SS+ TLP   +C+EEN G+DKR++RF+LP+GAT+NMDG A+++ VAA+FIAQ+N V 
Sbjct: 121 ATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVE 180

Query: 420 LDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRT 479
           L+ GQI T+ +TAT +SVGAA +P+ G++T+ +IL A+GLPT D+ L++AVDW++DR  T
Sbjct: 181 LNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLPLILAVDWIVDRTTT 240

Query: 480 SVNVVGDSFGAGIVYHLSK 498
            VNV GD+ GAGI++HL++
Sbjct: 241 VVNVEGDALGAGILHHLNQ 259


>gi|223468566 solute carrier family 1 member 5 isoform 3 [Homo
           sapiens]
          Length = 339

 Score =  276 bits (707), Expect = 3e-74
 Identities = 133/268 (49%), Positives = 197/268 (73%), Gaps = 1/268 (0%)

Query: 226 TKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIM 285
           T++ +  G E  +GMN+LGL+ F I FG+A+ K+G + +L++ FFN  NE  M LV  IM
Sbjct: 14  TRVKVPVGQEV-EGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIM 72

Query: 286 WYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPF 345
           WY+P+GI  L+ GKI+ ++D+ ++  +LG Y++  ++G  IHG + LPLIYF+ TRKNP+
Sbjct: 73  WYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPY 132

Query: 346 SFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYE 405
            F  GI     TA GT+SS+ TLP+  +C+EEN G+ K ++RF+LP+GAT+NMDG AL++
Sbjct: 133 RFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQ 192

Query: 406 AVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDIS 465
            VAA+FIAQ++   LD  +I+T+ +TAT +SVGAA IP+ G++T+ +IL AV LP + IS
Sbjct: 193 CVAAVFIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHIS 252

Query: 466 LLVAVDWLLDRMRTSVNVVGDSFGAGIV 493
           L++AVDWL+DR  T +NV GD+ GAG++
Sbjct: 253 LILAVDWLVDRSCTVLNVEGDALGAGLL 280


>gi|223468564 solute carrier family 1 member 5 isoform 2 [Homo
           sapiens]
          Length = 313

 Score =  273 bits (697), Expect = 4e-73
 Identities = 129/254 (50%), Positives = 189/254 (74%)

Query: 240 MNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGK 299
           MN+LGL+ F I FG+A+ K+G + +L++ FFN  NE  M LV  IMWY+P+GI  L+ GK
Sbjct: 1   MNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGK 60

Query: 300 IIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITAL 359
           I+ ++D+ ++  +LG Y++  ++G  IHG + LPLIYF+ TRKNP+ F  GI     TA 
Sbjct: 61  IVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAF 120

Query: 360 GTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVV 419
           GT+SS+ TLP+  +C+EEN G+ K ++RF+LP+GAT+NMDG AL++ VAA+FIAQ++   
Sbjct: 121 GTSSSSATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQS 180

Query: 420 LDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRT 479
           LD  +I+T+ +TAT +SVGAA IP+ G++T+ +IL AV LP + ISL++AVDWL+DR  T
Sbjct: 181 LDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCT 240

Query: 480 SVNVVGDSFGAGIV 493
            +NV GD+ GAG++
Sbjct: 241 VLNVEGDALGAGLL 254


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 40/139 (28%), Positives = 61/139 (43%), Gaps = 22/139 (15%)

Query: 399 DGTALYEAVAAIFIAQMNGV--VLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTA 456
           +G    EA A   +A  N V  +L GG ++       L  +GA  + + G  T+   L A
Sbjct: 112 EGVIPDEAKALSLLAPANAVAGLLPGGGLLPTP--NPLTQIGAVPLAALGAPTLDPALAA 169

Query: 457 VGLPTEDI-SLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIE 515
           +GLP  ++ S  +A D LL  M T V+   +   AG+V    KS+               
Sbjct: 170 LGLPGANLNSQSLAADQLLKLMST-VDPKLNHVAAGLVSPSLKSD--------------- 213

Query: 516 MTKTQSIYDDMKNHRESNS 534
            T ++ I + MK  RE+ S
Sbjct: 214 -TSSKEIEEAMKRVREAQS 231


>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
          Length = 547

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 3/97 (3%)

Query: 141 AIHP-GNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQ-ACFQQIQTVTKKVLVA 198
           AIHP GNP + +      K+++  + +  L+ I N+  + L + A   +  TV K   +A
Sbjct: 189 AIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDNTVVKTFSLA 248

Query: 199 PP-PDEEANATSAVVSLLNETVTEVPEETKMVIKKGL 234
               D+ A    A +  +NE +T V  E+  +  KG+
Sbjct: 249 NTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGI 285


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,178,794
Number of Sequences: 37866
Number of extensions: 760436
Number of successful extensions: 1962
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1935
Number of HSP's gapped (non-prelim): 13
length of query: 574
length of database: 18,247,518
effective HSP length: 108
effective length of query: 466
effective length of database: 14,157,990
effective search space: 6597623340
effective search space used: 6597623340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.