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Search of human proteins with 40254422
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens]
(1203 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens] 2472 0.0
gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens] 1392 0.0
gi|231571329 nitric oxide synthase 3 isoform 3 [Homo sapiens] 1211 0.0
gi|231571314 nitric oxide synthase 3 isoform 2 [Homo sapiens] 1211 0.0
gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens] 1209 0.0
gi|24041029 nitric oxide synthase 2A [Homo sapiens] 1158 0.0
gi|127139033 cytochrome P450 reductase [Homo sapiens] 250 5e-66
gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens] 219 1e-56
gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens] 219 1e-56
gi|7657393 NADPH dependent diflavin oxidoreductase 1 isoform b [... 198 3e-50
gi|221316705 NADPH dependent diflavin oxidoreductase 1 isoform a... 194 4e-49
gi|221316709 NADPH dependent diflavin oxidoreductase 1 isoform c... 184 4e-46
gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d... 182 1e-45
gi|50726981 radical S-adenosyl methionine and flavodoxin domains... 48 6e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni... 47 1e-04
gi|112421108 capicua homolog [Homo sapiens] 45 5e-04
gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [... 43 0.002
gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [... 43 0.002
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 43 0.002
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 43 0.002
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 43 0.002
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 43 0.002
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 43 0.002
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 43 0.002
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 43 0.002
gi|130502162 RAS protein activator like 3 [Homo sapiens] 42 0.005
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 40 0.013
gi|4507691 transformation/transcription domain-associated protei... 40 0.013
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 40 0.017
gi|55741675 hypothetical protein LOC22889 [Homo sapiens] 39 0.023
>gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens]
Length = 1203
Score = 2472 bits (6408), Expect = 0.0
Identities = 1203/1203 (100%), Positives = 1203/1203 (100%)
Query: 1 MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT 60
MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT
Sbjct: 1 MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT 60
Query: 61 QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP 120
QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP
Sbjct: 61 QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP 120
Query: 121 EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN 180
EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN
Sbjct: 121 EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN 180
Query: 181 APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD 240
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD
Sbjct: 181 APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD 240
Query: 241 FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP 300
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP
Sbjct: 241 FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP 300
Query: 301 ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST 360
ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
Sbjct: 301 ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST 360
Query: 361 EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH 420
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH
Sbjct: 361 EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH 420
Query: 421 HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 480
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
Sbjct: 421 HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 480
Query: 481 KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR 540
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
Sbjct: 481 KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR 540
Query: 541 LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS 600
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
Sbjct: 541 LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS 600
Query: 601 PRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF 660
PRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
Sbjct: 601 PRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF 660
Query: 661 CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA 720
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA
Sbjct: 661 CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA 720
Query: 721 RDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATIRSVENLQSSKSTRATIL 780
RDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATIRSVENLQSSKSTRATIL
Sbjct: 721 RDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATIRSVENLQSSKSTRATIL 780
Query: 781 VRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP 840
VRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP
Sbjct: 781 VRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP 840
Query: 841 PPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY 900
PPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY
Sbjct: 841 PPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY 900
Query: 901 EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVL 960
EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVL
Sbjct: 901 EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVL 960
Query: 961 AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP 1020
AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP
Sbjct: 961 AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP 1020
Query: 1021 FRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSRE 1080
FRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSRE
Sbjct: 1021 FRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSRE 1080
Query: 1081 PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELD 1140
PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELD
Sbjct: 1081 PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELD 1140
Query: 1141 EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDT 1200
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDT
Sbjct: 1141 EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDT 1200
Query: 1201 NSP 1203
NSP
Sbjct: 1201 NSP 1203
>gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]
Length = 1434
Score = 1392 bits (3603), Expect = 0.0
Identities = 678/1149 (59%), Positives = 853/1149 (74%), Gaps = 17/1149 (1%)
Query: 47 PPAPEHSPPSSPLTQPPEG------PKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCL 100
P + + PP+S P + P+F +VKNWE + DTL ++ + CT C+
Sbjct: 278 PYSEKEQPPTSGKQSPTKNGSPSKCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICM 337
Query: 101 GSLVFPRKLQGRPSPGPPAPEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAAT 160
GS++ P + RP QL A++FI+QYYSSIKR GS+AH +RL+EV E+ T
Sbjct: 338 GSIMHPSQHARRPED-VRTKGQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTT 396
Query: 161 GTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATN 220
TYQL+++EL++GAK AWRNA RCVGRIQW KLQVFDARDC +A MF YICNH+KYATN
Sbjct: 397 STYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATN 456
Query: 221 RGNLRSAITVFPQRCPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWT 280
+GNLRSAIT+FPQR G+ DFR+WNSQL+RYAGY+Q DGS GDPANV+ TE+CIQ GW
Sbjct: 457 KGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWK 516
Query: 281 PGNGRFDVLPLLLQAPDDPPELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNML 340
P GRFDVLPLLLQA + PELF +PPELVLEVP+ HP EWF LGL+WY LPAVSNML
Sbjct: 517 PPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNML 576
Query: 341 LEIGGLEFPAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAV 400
LEIGGLEF A PFSGWYM TEIG R+ CD RYNILE+VA M+LD R TSSLWKD+A V
Sbjct: 577 LEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALV 636
Query: 401 EINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVF 460
EIN+AVL+S+Q KVTIVDHH+AT SF+KH+ENE + RGGCPADW WIVPP+SGS+TPVF
Sbjct: 637 EINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVF 696
Query: 461 HQEMVNYFLSPAFRYQPDPWKGSAAKGTGITRKKT----FKEVANAVKISASLMGTVMAK 516
HQEM+NY L+P+F YQPDPW KGT T K FK++A AVK SA LMG MAK
Sbjct: 697 HQEMLNYRLTPSFEYQPDPWNTHVWKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAK 756
Query: 517 RVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGN 576
RVKATILY +ETG++Q+YA+ L +F+ AFD +V+ M+EYD+V LEHETLVLVVTSTFGN
Sbjct: 757 RVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGN 816
Query: 577 GDPPENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNT 636
GDPPENGE F ALMEM P + E+ KSYK+RFNS+S S N
Sbjct: 817 GDPPENGEKFGCALMEMRHPNSVQ---EERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNF 873
Query: 637 DSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFR 696
+SAG L +RF VFGLGSRAYPHFCAF AVDT LEELGGER+L++ +GDELCGQEEAFR
Sbjct: 874 ESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFR 933
Query: 697 GWAQAAFQAACETFCVGEDA--KAAARDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVH 754
WA+ F+AAC+ FCVG+D + A + S RSWKR ++RL+ AE +L GL +VH
Sbjct: 934 TWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELTQGLSNVH 993
Query: 755 RRKMFQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALL 814
++++ A + S +NLQS KS+R+TI VRL T G + LQYQPGDH+GV P N LV AL+
Sbjct: 994 KKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALI 1053
Query: 815 SRVEDPPAPTEPVAVEQLEKGSPG-GPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQL 873
R+ED P + V VE LE+ + G W + RLPPCT+ QA ++LDIT+PP+P
Sbjct: 1054 ERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDITTPPTPLQ 1113
Query: 874 LRLLSTLAEEPREQQELEALSQDPRRYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLP 933
L+ ++LA +E+Q L LS+ + YEEWKW + PT++EVLE+FPS+ +PA LLLTQL
Sbjct: 1114 LQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLS 1173
Query: 934 LLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFI 993
LLQPRYYS+SS+P +P E+HLTVA+++YRT+DG GP+H+GVCS+WL++++ + VPCF+
Sbjct: 1174 LLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQADELVPCFV 1233
Query: 994 RGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQERLHDIESKGLQPTPMTLVFGCRCSQL 1053
RGAPSF LP +P +PCILVGPGTGIAPFR FWQ+R DI+ KG+ P PM LVFGCR S++
Sbjct: 1234 RGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKI 1293
Query: 1054 DHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYVQDILRTELAAEVHRVLCLERGHMFV 1113
DH+YR+E A+ +GVF + TA+SREPD PK YVQDIL+ +LA V+R L + GH++V
Sbjct: 1294 DHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKEQGGHIYV 1353
Query: 1114 CGDVTMATNVLQTVQRILATEGDMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRI 1173
CGDVTMA +VL+ +QRI+ +G + ++AG I +RD RYHEDIFG+TLRT EVT+R+
Sbjct: 1354 CGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRL 1413
Query: 1174 RTQSFSLQE 1182
R++S + E
Sbjct: 1414 RSESIAFIE 1422
>gi|231571329 nitric oxide synthase 3 isoform 3 [Homo sapiens]
Length = 614
Score = 1211 bits (3134), Expect = 0.0
Identities = 585/591 (98%), Positives = 588/591 (99%)
Query: 1 MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT 60
MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT
Sbjct: 1 MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT 60
Query: 61 QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP 120
QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP
Sbjct: 61 QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP 120
Query: 121 EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN 180
EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN
Sbjct: 121 EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN 180
Query: 181 APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD 240
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD
Sbjct: 181 APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD 240
Query: 241 FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP 300
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP
Sbjct: 241 FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP 300
Query: 301 ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST 360
ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
Sbjct: 301 ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST 360
Query: 361 EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH 420
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH
Sbjct: 361 EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH 420
Query: 421 HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 480
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
Sbjct: 421 HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 480
Query: 481 KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR 540
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
Sbjct: 481 KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR 540
Query: 541 LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALM 591
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGE + A++
Sbjct: 541 LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGERWGFAML 591
>gi|231571314 nitric oxide synthase 3 isoform 2 [Homo sapiens]
Length = 596
Score = 1211 bits (3132), Expect = 0.0
Identities = 585/585 (100%), Positives = 585/585 (100%)
Query: 1 MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT 60
MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT
Sbjct: 1 MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT 60
Query: 61 QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP 120
QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP
Sbjct: 61 QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP 120
Query: 121 EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN 180
EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN
Sbjct: 121 EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN 180
Query: 181 APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD 240
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD
Sbjct: 181 APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD 240
Query: 241 FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP 300
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP
Sbjct: 241 FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP 300
Query: 301 ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST 360
ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
Sbjct: 301 ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST 360
Query: 361 EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH 420
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH
Sbjct: 361 EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH 420
Query: 421 HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 480
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
Sbjct: 421 HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 480
Query: 481 KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR 540
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
Sbjct: 481 KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR 540
Query: 541 LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGES 585
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGES
Sbjct: 541 LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGES 585
>gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens]
Length = 629
Score = 1209 bits (3128), Expect = 0.0
Identities = 584/584 (100%), Positives = 584/584 (100%)
Query: 1 MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT 60
MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT
Sbjct: 1 MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT 60
Query: 61 QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP 120
QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP
Sbjct: 61 QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP 120
Query: 121 EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN 180
EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN
Sbjct: 121 EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN 180
Query: 181 APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD 240
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD
Sbjct: 181 APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD 240
Query: 241 FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP 300
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP
Sbjct: 241 FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP 300
Query: 301 ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST 360
ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
Sbjct: 301 ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST 360
Query: 361 EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH 420
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH
Sbjct: 361 EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH 420
Query: 421 HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 480
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
Sbjct: 421 HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 480
Query: 481 KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR 540
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
Sbjct: 481 KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR 540
Query: 541 LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGE 584
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGE
Sbjct: 541 LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGE 584
>gi|24041029 nitric oxide synthase 2A [Homo sapiens]
Length = 1153
Score = 1158 bits (2996), Expect = 0.0
Identities = 578/1123 (51%), Positives = 744/1123 (66%), Gaps = 54/1123 (4%)
Query: 62 PPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
P P+ R+KNW G DTL +A+ C + CLGS++ P+ L P P P+
Sbjct: 78 PLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMTPKSLTRGPRDKPTPPD 137
Query: 122 QLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA 181
+LL QA +F+NQYY S K + + H R++ V E+ TGTYQL EL+F KQAWRNA
Sbjct: 138 ELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNA 197
Query: 182 PRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDF 241
PRC+GRIQW LQVFDAR C +A+EMF +IC H++Y+TN GN+RSAITVFPQR G+ DF
Sbjct: 198 PRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDF 257
Query: 242 RIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPPE 301
R+WN+QL+RYAGY+ DGS+RGDPANVE T+LCI GW P GRFDV+PL+LQA PE
Sbjct: 258 RVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPE 317
Query: 302 LFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTE 361
LF +PP+LVLEV +EHP EWF L L+WYALPAV+NMLLE+GGLEFP PF+GWYM TE
Sbjct: 318 LFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTE 377
Query: 362 IGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH 421
IG R+ CD RYNILE+V M L+T +SLWKD+A VEIN+AVLHS+Q VTI+DHH
Sbjct: 378 IGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHH 437
Query: 422 AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK 481
+A SFMK+++NE ++RGGCPADW W+VPP+SGS+TPVFHQEM+NY LSP + YQ + WK
Sbjct: 438 SAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWK 497
Query: 482 GSA---AKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQL 538
K R+ K + AV + LM MA RV+ TIL+ +ETG++++ A L
Sbjct: 498 THVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDL 557
Query: 539 GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYN 598
G LF AF+P+V+CMD+Y + LE E L+LVVTSTFGNGD P NGE +L +
Sbjct: 558 GALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEKLKKSLFML----- 612
Query: 599 SSPRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYP 658
KE +N R+ VFGLGS YP
Sbjct: 613 --------------------------------KELNN--------KFRYAVFGLGSSMYP 632
Query: 659 HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKA 718
FCAFA +D +L LG +L +G+GDEL GQE+AFR WA F+AACETF V
Sbjct: 633 RFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETFDVRGKQHI 692
Query: 719 AARDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATIRSVENLQSSKSTRAT 778
+++ +W YRL ++ L L L +H + +F ++S +NLQS S+RAT
Sbjct: 693 QIPKLYTSNVTWDPHHYRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRAT 752
Query: 779 ILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPG 838
ILV L +GL Y PG+H+GVCP N+P LV+ +L RV D P P + V +E L++
Sbjct: 753 ILVELSCEDGQGLNYLPGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDESG-- 810
Query: 839 GPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPR 898
WV D RLPPC+L QALT+FLDIT+PP+ LL+ L+ +A E E+Q LEAL Q P
Sbjct: 811 ---SYWVSDKRLPPCSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRLEALCQ-PS 866
Query: 899 RYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVA 958
Y +WK+ PT LEVLE+FPS+ + A LL+QLP+L+PR+YS+SS+ P EIHLTVA
Sbjct: 867 EYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVA 926
Query: 959 VLAYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGI 1018
V+ Y T+DG GPLH+GVCSTWL+ LKP DPVPCF+R A F LP DPS PCIL+GPGTGI
Sbjct: 927 VVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCFVRNASGFHLPEDPSHPCILIGPGTGI 986
Query: 1019 APFRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFS 1078
APFR FWQ+RLHD + KG++ MTLVFGCR DH+Y++E+ Q+GV V TA+S
Sbjct: 987 APFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYS 1046
Query: 1079 REPDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDME 1138
R P PK YVQDILR +LA+EV RVL E GH++VCGDV MA +V T+++++A + +
Sbjct: 1047 RLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVRMARDVAHTLKQLVAAKLKLN 1106
Query: 1139 LDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQ 1181
++ D L+ Q+RYHEDIFG + R+ Q SL+
Sbjct: 1107 EEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDRVAVQPSSLE 1149
>gi|127139033 cytochrome P450 reductase [Homo sapiens]
Length = 680
Score = 250 bits (639), Expect = 5e-66
Identities = 213/712 (29%), Positives = 331/712 (46%), Gaps = 125/712 (17%)
Query: 492 RKKTFKEVANAVKISASLMGTVMAKRVKAT-----ILYGSETGRAQSYAQQLGRLFRKAF 546
+K+ E +++S+ + +++K T + YGS+TG A+ +A +L + + +
Sbjct: 50 KKEEVPEFTKIQTLTSSVRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHR-Y 108
Query: 547 DPRVLCMD--EYDVVSLEH-----ETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNS 599
R + D EYD+ L LV+ +T+G GDP +N + F L E
Sbjct: 109 GMRGMSADPEEYDLADLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQE------- 161
Query: 600 SPRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPH 659
++ D +G ++F VFGLG++ Y H
Sbjct: 162 ----------------------------------TDVDLSG----VKFAVFGLGNKTYEH 183
Query: 660 FCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCV---GEDA 716
F A + VD RLE+LG +R+ +LG GD+ EE F W + + A CE F V GE++
Sbjct: 184 FNAMGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEES 243
Query: 717 K------AAARDIFSPK---------RSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQA 761
DI + K +S++ Q+ A+ L + RK+ Q
Sbjct: 244 SIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAV-----TTNRKLNQG 298
Query: 762 TIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPP 821
T R + +L+ LD + ++Y+ GDH+ V P N LV L +
Sbjct: 299 TERHLMHLE------------LDISDSK-IRYESGDHVAVYPANDSALVNQLGKILG--- 342
Query: 822 APTEPV-AVEQLEKGSPGGPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTL 880
A + V ++ L++ S + P P + R ALT++LDIT+PP +L L+
Sbjct: 343 ADLDVVMSLNNLDEESNK-------KHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQY 395
Query: 881 AEEPREQQELEALS----QDPRRYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQ 936
A EP EQ+ L ++ + Y W +L +L+ PS+ P L LP LQ
Sbjct: 396 ASEPSEQELLRKMASSSGEGKELYLSWVVEARRHILAILQDCPSLRPPIDHLCELLPRLQ 455
Query: 937 PRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKPGDP------VP 990
RYYS++S+ HP +H+ V+ Y T+ G ++ GV + WL +P VP
Sbjct: 456 ARYYSIASSSKVHPNSVHICAVVVEYETK--AGRINKGVATNWLRAKEPAGENGGRALVP 513
Query: 991 CFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQERLHDIESKGLQPTPMTLVFGCRC 1050
F+R + FRLP + P I+VGPGTG+APF GF QER + +G + L +GCR
Sbjct: 514 MFVRKS-QFRLPFKATTPVIMVGPGTGVAPFIGFIQERAW-LRQQGKEVGETLLYYGCRR 571
Query: 1051 SQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYVQDILRTELAAEVHRVLCLERG- 1109
S D+LYR+E+ + G ++ AFSRE + K YVQ +L+ + H +E G
Sbjct: 572 SDEDYLYREELAQFHRDGALTQLNVAFSREQSH-KVYVQHLLKQD---REHLWKLIEGGA 627
Query: 1110 HMFVCGDV-TMATNVLQTVQRILATEGDMELDEAGDVIGVLRDQQRYHEDIF 1160
H++VCGD MA +V T I+A G ME +A D I L + RY D++
Sbjct: 628 HIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTKGRYSLDVW 679
>gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens]
Length = 698
Score = 219 bits (558), Expect = 1e-56
Identities = 200/746 (26%), Positives = 311/746 (41%), Gaps = 161/746 (21%)
Query: 522 ILYGSETGRAQSYAQQL-GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVT-STFGNGDP 579
+LY ++ G+A++ A+++ + F + C+ E D L+ ET LVV ST G GDP
Sbjct: 6 LLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDP 65
Query: 580 PENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSA 639
P+ F + + P +
Sbjct: 66 PDTARKFVKEIQNQTLPVDF---------------------------------------- 85
Query: 640 GALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWA 699
LR+ + GLG Y +FC + +D RL+ELG G D+ G E W
Sbjct: 86 --FAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGARHFYDTGHADDCVGLELVVEPWI 143
Query: 700 QAAFQAACETF--CVGEDAKAAARDIFSPKRS----WKRQRYRLSAQAEGLQL------- 746
+ A + F G++ + A + SP S K + + +Q E L+
Sbjct: 144 AGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLVKSELLHIESQVELLRFDDSGRKD 203
Query: 747 --------------------------------------LPGL----IHVHRRKMF----- 759
+PGL + VH ++
Sbjct: 204 SEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASLNIPGLPPEYLQVHLQESLGQEES 263
Query: 760 QATIRSVE-----------NLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPG 808
Q ++ S + L ++ + + T+LV LD + YQPGD V PN
Sbjct: 264 QVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDISNTD-FSYQPGDAFSVICPNSDS 322
Query: 809 LVEALLSRVEDPPAPTE----PVAVEQLEKGS--PGGPPPGWVRDPRLPPCTLRQALTFF 862
V++LL R++ + + +KG+ P P G C+L+ T+
Sbjct: 323 EVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHIPAG---------CSLQFIFTWC 373
Query: 863 LDITSPPSPQLLRLLSTLAEEPREQQELEAL--SQDPRRYEEWKWFRCPTLLEVLEQFPS 920
L+I + P LR L + E++ L+ L Q Y + C LL++L FPS
Sbjct: 374 LEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDACACLLDLLLAFPS 433
Query: 921 VALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWL 980
P LLL LP LQPR YS +S+ HPG++H ++ + + L GVC+ WL
Sbjct: 434 CQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTATTEVLRKGVCTGWL 493
Query: 981 -----SQLKP-------------GDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFR 1022
S L+P + R SF LP DPS+P I+VGPGTGIAPF
Sbjct: 494 ALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFI 553
Query: 1023 GFWQ--ERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSR- 1079
GF Q E+L + G M L FGCR D+L+R E+++ + G+ + +FSR
Sbjct: 554 GFLQHREKLQEQHPDG-NFGAMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFSRD 612
Query: 1080 ----EPDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDV-TMATNVLQTVQRILATE 1134
E + P YVQD ++ +V R+L E GH++VCGD MA +V + +I++ E
Sbjct: 613 APVGEEEAPAKYVQDNIQLH-GQQVARILLQENGHIYVCGDAKNMAKDVHDALVQIISKE 671
Query: 1135 GDMELDEAGDVIGVLRDQQRYHEDIF 1160
+E EA + L++++RY +DI+
Sbjct: 672 VGVEKLEAMKTLATLKEEKRYLQDIW 697
>gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens]
Length = 725
Score = 219 bits (558), Expect = 1e-56
Identities = 200/746 (26%), Positives = 311/746 (41%), Gaps = 161/746 (21%)
Query: 522 ILYGSETGRAQSYAQQL-GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVT-STFGNGDP 579
+LY ++ G+A++ A+++ + F + C+ E D L+ ET LVV ST G GDP
Sbjct: 33 LLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDP 92
Query: 580 PENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSA 639
P+ F + + P +
Sbjct: 93 PDTARKFVKEIQNQTLPVDF---------------------------------------- 112
Query: 640 GALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWA 699
LR+ + GLG Y +FC + +D RL+ELG G D+ G E W
Sbjct: 113 --FAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGARHFYDTGHADDCVGLELVVEPWI 170
Query: 700 QAAFQAACETF--CVGEDAKAAARDIFSPKRS----WKRQRYRLSAQAEGLQL------- 746
+ A + F G++ + A + SP S K + + +Q E L+
Sbjct: 171 AGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLVKSELLHIESQVELLRFDDSGRKD 230
Query: 747 --------------------------------------LPGL----IHVHRRKMF----- 759
+PGL + VH ++
Sbjct: 231 SEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASLNIPGLPPEYLQVHLQESLGQEES 290
Query: 760 QATIRSVE-----------NLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPG 808
Q ++ S + L ++ + + T+LV LD + YQPGD V PN
Sbjct: 291 QVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDISNTD-FSYQPGDAFSVICPNSDS 349
Query: 809 LVEALLSRVEDPPAPTE----PVAVEQLEKGS--PGGPPPGWVRDPRLPPCTLRQALTFF 862
V++LL R++ + + +KG+ P P G C+L+ T+
Sbjct: 350 EVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHIPAG---------CSLQFIFTWC 400
Query: 863 LDITSPPSPQLLRLLSTLAEEPREQQELEAL--SQDPRRYEEWKWFRCPTLLEVLEQFPS 920
L+I + P LR L + E++ L+ L Q Y + C LL++L FPS
Sbjct: 401 LEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDACACLLDLLLAFPS 460
Query: 921 VALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWL 980
P LLL LP LQPR YS +S+ HPG++H ++ + + L GVC+ WL
Sbjct: 461 CQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTATTEVLRKGVCTGWL 520
Query: 981 -----SQLKP-------------GDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFR 1022
S L+P + R SF LP DPS+P I+VGPGTGIAPF
Sbjct: 521 ALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFI 580
Query: 1023 GFWQ--ERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSR- 1079
GF Q E+L + G M L FGCR D+L+R E+++ + G+ + +FSR
Sbjct: 581 GFLQHREKLQEQHPDG-NFGAMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFSRD 639
Query: 1080 ----EPDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDV-TMATNVLQTVQRILATE 1134
E + P YVQD ++ +V R+L E GH++VCGD MA +V + +I++ E
Sbjct: 640 APVGEEEAPAKYVQDNIQLH-GQQVARILLQENGHIYVCGDAKNMAKDVHDALVQIISKE 698
Query: 1135 GDMELDEAGDVIGVLRDQQRYHEDIF 1160
+E EA + L++++RY +DI+
Sbjct: 699 VGVEKLEAMKTLATLKEEKRYLQDIW 724
>gi|7657393 NADPH dependent diflavin oxidoreductase 1 isoform b [Homo
sapiens]
Length = 597
Score = 198 bits (503), Expect = 3e-50
Identities = 187/655 (28%), Positives = 300/655 (45%), Gaps = 86/655 (13%)
Query: 522 ILYGSETGRAQSYAQQLGR-LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPP 580
+L+GS+TG AQ +++LGR R+ RV +D Y VV+L +E LV+ V +T G GDPP
Sbjct: 8 VLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP 67
Query: 581 ENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWR---RKRKESSNTD 637
+N ++F WR RK S+
Sbjct: 68 DNMKNF---------------------------------------WRFIFRKNLPST--- 85
Query: 638 SAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDEL--CGQEEAF 695
AL + F V GLG +Y F A+ + RL +LGG LL + GD+ G + A
Sbjct: 86 ---ALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPVCLGDDQHELGPDAAV 142
Query: 696 RGWAQAAFQAACETFCVGEDAKAAARDIFSPKR-SWKRQRYRLSAQAEGLQLL-PGLIHV 753
W + + + + P + + + S +EG ++ PG
Sbjct: 143 DPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEP 202
Query: 754 -HRRKMFQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEA 812
K F A + S + + + L+ D G G+ + GD + + P N V+
Sbjct: 203 PSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGS-GISFAAGDVVLIQPSNSAAHVQR 261
Query: 813 LLSRVEDPPAPTEPVAVEQLEKGSPGGPPPGWVRDPRLP-PCTLRQALTFFLDITSPPSP 871
+ +P + L+ P P RLP PC++R ++ +LDI S P
Sbjct: 262 FCQVLG-----LDPDQLFMLQPREPDVSSP-----TRLPQPCSMRHLVSHYLDIASVPRR 311
Query: 872 QLLRLLSTLAEEPREQQELEALSQDPRRYEEWKWFRCP--TLLEVLEQFP--SVALPAPL 927
LL+ L+ E+++L S + E +++ P T+LEVL FP + A+P
Sbjct: 312 SFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDY 371
Query: 928 LLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKPGD 987
LL +P+++PR +S++S+ THP + + VAV+ ++T+ L G+CS+WL+ L PG
Sbjct: 372 LLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTR--LKEPRRGLCSSWLASLDPGQ 429
Query: 988 P---VPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQERLHDIESKGLQPTPMTL 1044
VP ++R S P P P I+VGPGTG+APFR QER+ ++G T L
Sbjct: 430 GPVRVPLWVRPG-SLAFPETPDTPVIMVGPGTGVAPFRAAIQERV----AQG--QTGNFL 482
Query: 1045 VFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYVQDILRTELAAEVHRVL 1104
FGCR D + E Q ++R ++ AFSRE + K YVQ LR EL + V +L
Sbjct: 483 FFGCRWRDQDFYWEAEWQELEKRDCL-TLIPAFSREQEQ-KVYVQHRLR-ELGSLVWELL 539
Query: 1105 CLERGHMFVCGDV-TMATNVLQTVQRILATEGDMELDEAGDVIGVLRDQQRYHED 1158
+ + ++ G+ +M +V + + I EG + +A + L+ +R+ +
Sbjct: 540 DRQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRFQTE 594
>gi|221316705 NADPH dependent diflavin oxidoreductase 1 isoform a
[Homo sapiens]
Length = 606
Score = 194 bits (493), Expect = 4e-49
Identities = 187/663 (28%), Positives = 299/663 (45%), Gaps = 93/663 (14%)
Query: 522 ILYGSETGRAQSYAQQLGR-LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPP 580
+L+GS+TG AQ +++LGR R+ RV +D Y VV+L +E LV+ V +T G GDPP
Sbjct: 8 VLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP 67
Query: 581 ENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWR---RKRKESSNTD 637
+N ++F WR RK S+
Sbjct: 68 DNMKNF---------------------------------------WRFIFRKNLPST--- 85
Query: 638 SAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDEL--CGQEEAF 695
AL + F V GLG +Y F A+ + RL +LGG LL + GD+ G + A
Sbjct: 86 ---ALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPVCLGDDQHELGPDAAV 142
Query: 696 RGWAQAAFQAACETFCVGEDAKAAARDIFSPKR-SWKRQRYRLSAQAEGLQLL-PGLIHV 753
W + + + + P + + + S +EG ++ PG
Sbjct: 143 DPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEP 202
Query: 754 -HRRKMFQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEA 812
K F A + S + + + L+ D G G+ + GD + + P N V+
Sbjct: 203 PSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGS-GISFAAGDVVLIQPSNSAAHVQR 261
Query: 813 LLSRVEDPPAPTEPVAVEQLEKGSPGGPPPGWVRDPRLP-PCTLRQALTFFLDITSPPSP 871
+ +P + L+ P P RLP PC++R ++ +LDI S P
Sbjct: 262 FCQVLG-----LDPDQLFMLQPREPDVSSP-----TRLPQPCSMRHLVSHYLDIASVPRR 311
Query: 872 QLLRLLSTLAEEPREQQELEALSQDPRRYEEWKWFRCP--TLLEVLEQFP--SVALPAPL 927
LL+ L+ E+++L S + E +++ P T+LEVL FP + A+P
Sbjct: 312 SFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDY 371
Query: 928 LLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKPGD 987
LL +P+++PR +S++S+ THP + + VAV+ ++T+ L G+CS+WL+ L PG
Sbjct: 372 LLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTR--LKEPRRGLCSSWLASLDPGQ 429
Query: 988 P---VPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQERLHDIESKGLQPTPMTL 1044
VP ++R S P P P I+VGPGTG+APFR QER+ ++G T L
Sbjct: 430 GPVRVPLWVRPG-SLAFPETPDTPVIMVGPGTGVAPFRAAIQERV----AQG--QTGNFL 482
Query: 1045 VFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREP--------DNPKTYVQDILRTEL 1096
FGCR D + E Q ++R ++ AFSRE K YVQ LR EL
Sbjct: 483 FFGCRWRDQDFYWEAEWQELEKRDCL-TLIPAFSREQPPALFSALQEQKVYVQHRLR-EL 540
Query: 1097 AAEVHRVLCLERGHMFVCGDV-TMATNVLQTVQRILATEGDMELDEAGDVIGVLRDQQRY 1155
+ V +L + + ++ G+ +M +V + + I EG + +A + L+ +R+
Sbjct: 541 GSLVWELLDRQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRF 600
Query: 1156 HED 1158
+
Sbjct: 601 QTE 603
>gi|221316709 NADPH dependent diflavin oxidoreductase 1 isoform c
[Homo sapiens]
Length = 590
Score = 184 bits (467), Expect = 4e-46
Identities = 184/655 (28%), Positives = 297/655 (45%), Gaps = 93/655 (14%)
Query: 522 ILYGSETGRAQSYAQQLGR-LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPP 580
+L+GS+TG AQ +++LGR R+ RV +D Y VV+L +E LV+ V +T G GDPP
Sbjct: 8 VLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP 67
Query: 581 ENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWR---RKRKESSNTD 637
+N ++F WR RK S+
Sbjct: 68 DNMKNF---------------------------------------WRFIFRKNLPST--- 85
Query: 638 SAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDEL--CGQEEAF 695
AL + F V GLG +Y F A+ + RL +LGG LL + GD+ G + A
Sbjct: 86 ---ALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPVCLGDDQHELGPDAAV 142
Query: 696 RGWAQAAFQAACETFCVGEDAKAAARDIFSPKR-SWKRQRYRLSAQAEGLQLL-PGLIHV 753
W + + + + P + + + S +EG ++ PG
Sbjct: 143 DPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEP 202
Query: 754 -HRRKMFQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEA 812
K F A + S + + + L+ D G G+ + GD + + P N V+
Sbjct: 203 PSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGS-GISFAAGDVVLIQPSNSAAHVQR 261
Query: 813 LLSRVEDPPAPTEPVAVEQLEKGSPGGPPPGWVRDPRLP-PCTLRQALTFFLDITSPPSP 871
+ +P + L+ P P RLP PC++R ++ +LDI S P
Sbjct: 262 FCQVLG-----LDPDQLFMLQPREPDVSSP-----TRLPQPCSMRHLVSHYLDIASVPRR 311
Query: 872 QLLRLLSTLAEEPREQQELEALSQDPRRYEEWKWFRCP--TLLEVLEQFP--SVALPAPL 927
LL+ L+ E+++L S + E +++ P T+LEVL FP + A+P
Sbjct: 312 SFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDY 371
Query: 928 LLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKPGD 987
LL +P+++PR +S++S+ + + VAV+ ++T+ L G+CS+WL+ L PG
Sbjct: 372 LLDLIPVIRPRAFSIASS-------LLILVAVVQFQTR--LKEPRRGLCSSWLASLDPGQ 422
Query: 988 P---VPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQERLHDIESKGLQPTPMTL 1044
VP ++R S P P P I+VGPGTG+APFR QER+ ++G T L
Sbjct: 423 GPVRVPLWVRPG-SLAFPETPDTPVIMVGPGTGVAPFRAAIQERV----AQG--QTGNFL 475
Query: 1045 VFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYVQDILRTELAAEVHRVL 1104
FGCR D + E Q ++R ++ AFSRE + K YVQ LR EL + V +L
Sbjct: 476 FFGCRWRDQDFYWEAEWQELEKRDCL-TLIPAFSREQEQ-KVYVQHRLR-ELGSLVWELL 532
Query: 1105 CLERGHMFVCGDV-TMATNVLQTVQRILATEGDMELDEAGDVIGVLRDQQRYHED 1158
+ + ++ G+ +M +V + + I EG + +A + L+ +R+ +
Sbjct: 533 DRQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRFQTE 587
>gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d
[Homo sapiens]
Length = 521
Score = 182 bits (463), Expect = 1e-45
Identities = 179/597 (29%), Positives = 267/597 (44%), Gaps = 113/597 (18%)
Query: 522 ILYGSETGRAQSYAQQLGR-LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPP 580
+L+GS+TG AQ +++LGR R+ RV +D Y VV+L +E LV+ V +T G GDPP
Sbjct: 8 VLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP 67
Query: 581 ENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWR---RKRKESSNTD 637
+N ++F WR RK S+
Sbjct: 68 DNMKNF---------------------------------------WRFIFRKNLPST--- 85
Query: 638 SAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDEL--CGQEEAF 695
AL + F V GLG +Y F A+ + RL +LGG LL + GD+ G F
Sbjct: 86 ---ALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPVCLGDDQHELGLPSKF 142
Query: 696 RGWAQAAFQAACETFCVGEDAKAAARDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHR 755
Q A T G + + A G Q P
Sbjct: 143 ---TLLFLQEAPST---GSEGQRVAHP--------------------GSQEPPS-----E 171
Query: 756 RKMFQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLS 815
K F A + S + + + L+ D G G+ + GD + + P N V+
Sbjct: 172 SKPFLAPMISNQRVTGPSHFQDVRLIEFDILGS-GISFAAGDVVLIQPSNSAAHVQRFCQ 230
Query: 816 RVEDPPAPTEPVAVEQLEKGSPGGPPPGWVRDPRLP-PCTLRQALTFFLDITSPPSPQLL 874
+ +P + L+ P P RLP PC++R ++ +LDI S P
Sbjct: 231 VLG-----LDPDQLFMLQPREPDVSSP-----TRLPQPCSMRHLVSHYLDIASVPRRSFF 280
Query: 875 RLLSTLAEEPREQQELEALSQDPRRYEEWKWFRCP--TLLEVLEQFP--SVALPAPLLLT 930
LL+ L+ E+++L S + E +++ P T+LEVL FP + A+P LL
Sbjct: 281 ELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLD 340
Query: 931 QLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKPGDP-- 988
+P+++PR +S++S+ THP + + VAV+ ++T+ L G+CS+WL+ L PG
Sbjct: 341 LIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTR--LKEPRRGLCSSWLASLDPGQGPV 398
Query: 989 -VPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQERLHDIESKGLQPTPMTLVFG 1047
VP ++R S P P P I+VGPGTG+APFR QER+ ++G T L FG
Sbjct: 399 RVPLWVRPG-SLAFPETPDTPVIMVGPGTGVAPFRAAIQERV----AQG--QTGNFLFFG 451
Query: 1048 CRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYVQDILRTELAAEVHRVL 1104
CR D + E Q ++R ++ AFSRE + K YVQ LR EL + V +L
Sbjct: 452 CRWRDQDFYWEAEWQELEKRDCL-TLIPAFSREQEQ-KVYVQHRLR-ELGSLVWELL 505
>gi|50726981 radical S-adenosyl methionine and flavodoxin domains 1
[Homo sapiens]
Length = 732
Score = 47.8 bits (112), Expect = 6e-05
Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 47/191 (24%)
Query: 522 ILYGSETGRAQSYAQQLGRLFRKAFDP-RVLCMDEYD-----VVSLEHETLVLVVTSTFG 575
I YGS+TG A+ +A L P ++ + EYD + + + + + + +T+
Sbjct: 81 IFYGSQTGTAKGFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYT 140
Query: 576 NGDPPENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSN 635
+G P E+ E F L E S + K+Y
Sbjct: 141 DGLPTESAEWFCKWLEEASIDFRFG------KTY-------------------------- 168
Query: 636 TDSAGALGTLRFCVFGLGSRAYP-HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEA 694
L +R+ VFGLG+ AY HF + VD L LG R++ G+GD C ++
Sbjct: 169 ------LKGMRYAVFGLGNSAYASHFNKVGKNVDKWLWMLGAHRVMSRGEGD--CDVVKS 220
Query: 695 FRGWAQAAFQA 705
G +A F+A
Sbjct: 221 KHGSIEADFRA 231
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 46.6 bits (109), Expect = 1e-04
Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 23/106 (21%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQ---------PPEGPKFPRVKNWEVGS 78
K GPATP+P+ + P ++ PP+P+ SP ++P + PP P G+
Sbjct: 997 KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056
Query: 79 ITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSP---GPPAPE 121
T + + + GP TP L+G P+P PP+P+
Sbjct: 1057 PTTPAATLPSPKGGPATP-----------SLKGAPTPPAATPPSPK 1091
Score = 42.4 bits (98), Expect = 0.003
Identities = 26/101 (25%), Positives = 39/101 (38%), Gaps = 8/101 (7%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSP--------PSSPLTQPPEGPKFPRVKNWEVGSI 79
K GPATP+P+ + P + PP+P+ P P+ P PP P + G+
Sbjct: 974 KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033
Query: 80 TYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP 120
T + + + P G+ P P GP P
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074
Score = 42.0 bits (97), Expect = 0.004
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 22/105 (20%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSP--------PSSPLTQPPE---GPKFPRVKNWEV 76
K GPATP+P+ + P + PP+P+ P P+ P PP GP P K
Sbjct: 951 KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK---- 1006
Query: 77 GSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
G+ T ++ P +P+ + FP+ P+ PP+P+
Sbjct: 1007 GAPTPPAVT-------PPSPKGSPAATPFPKGASTPPAATPPSPK 1044
Score = 39.7 bits (91), Expect = 0.017
Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 23/102 (22%)
Query: 31 PATPAPEPSRAPASLLPPAPEHSP--------PSSPLTQPPE---GPKFPRVKNWEVGSI 79
PA+P+P+ + P + PP+P+ P P+ P PP GP P K G+
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK----GAP 986
Query: 80 TYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
T + + + GP TP P+ P+ PP+P+
Sbjct: 987 TPPAATPPSPKGGPATPS--------PKGAPTPPAVTPPSPK 1020
Score = 37.4 bits (85), Expect = 0.087
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEG-PKFPRVKNWEVGSITYDTLSA 86
K GPAT P+ + P + PP+P+ SP T PP+G P P V +
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPK----GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 87 QAQQDGPCTPRRCLGSL--VFPRKLQGRPSPGPPAPEQ 122
+ + GP TP G +G P+ PP+P++
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391
Score = 36.6 bits (83), Expect = 0.15
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 17/102 (16%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPE--------HSPPSSPLTQPPEGPKFPRVKNWEVGSI 79
K GPATP+P+ + P + PP+P+ P++P PP PK G+
Sbjct: 1091 KGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP-SPKGGLATPPPKGAP 1149
Query: 80 TYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
T + + + G TP P+ P+ PP+P+
Sbjct: 1150 TTPAATPPSPKGGLATPP--------PKGAPTTPAATPPSPK 1183
Score = 35.8 bits (81), Expect = 0.25
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 18/95 (18%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEG-PKFPRVKNWEVGSITYDTLSA 86
K+GPATPAP+ +APA + + SP + T P+G P P K G+ T +
Sbjct: 897 KEGPATPAPK--QAPALSMTSS---SPKKARATPAPKGIPASPSPK----GAPTPPAATP 947
Query: 87 QAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
+ + GP TP P+ P+ PP+P+
Sbjct: 948 PSPKGGPATPS--------PKWAPTPPAATPPSPK 974
Score = 35.4 bits (80), Expect = 0.33
Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 20/115 (17%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSP----------PSSPLTQPPEGPKFPRVKNWEVG 77
K GPA P P R PA P SP P++P+T+ EG P +
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR--EGAATPSKGDLTPP 1436
Query: 78 SITYDTL----SAQAQQDGPCTPRRCLGSLVFPRKLQGRPSP-GPPAPEQLLSQA 127
++T +L + A + GP TP G P PSP PPAP+Q+ + +
Sbjct: 1437 AVTPVSLKKAPATSAPKGGPATP-SSKGDPTLPAVTP--PSPKEPPAPKQVATSS 1488
Score = 35.0 bits (79), Expect = 0.43
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVGSITYDTLSAQ 87
K GPATP+ + ++ PP+P+ PP+ PK +G+ T +
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPK-EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511
Query: 88 AQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPEQLL 124
+ ++ P TP + L + +P AP++ L
Sbjct: 1512 SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548
Score = 34.7 bits (78), Expect = 0.56
Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 17/102 (16%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSP--------PSSPLTQPPEGPKFPRVKNWEVGSI 79
K GPATP+ + + P + PP+P+ P P P PP PK G+
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP-SPKGGLATPPHKGAP 1126
Query: 80 TYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
T + + + G TP P+ P+ PP+P+
Sbjct: 1127 TTPAATPPSPKGGLATPP--------PKGAPTTPAATPPSPK 1160
Score = 32.7 bits (73), Expect = 2.1
Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 10/94 (10%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVGSITYDTLSAQ 87
K P TPA P L P+P+ P++P PP PK G+ T +
Sbjct: 1169 KGAPTTPAATPPSPKGGLATPSPK-GAPTTPAATPP-SPKGGLATPSPKGAPTTPAATPP 1226
Query: 88 AQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
+ + G TP P+ P+ PP+P+
Sbjct: 1227 SPKGGLATPS--------PKGAPTTPAATPPSPK 1252
Score = 32.3 bits (72), Expect = 2.8
Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSPPSSP----LTQP---PEGPKFPRVKNWEVGSIT 80
K G ATP + + PA + PP+P+ P +SP T P P PK G+ T
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334
Query: 81 YDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPA 119
++ + + P P S P + P PPA
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Score = 32.3 bits (72), Expect = 2.8
Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 11/73 (15%)
Query: 801 VCPPNRPGLVEALLSRVEDPP--APTEPVAVEQLEKGSPGGPPP-GWVRDPRLPPCTLRQ 857
V PP+ G PP APT P A KGSPG PPP G P + P + +
Sbjct: 1292 VTPPSPKG------GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345
Query: 858 ALTFFLDITSPPS 870
T L T+P S
Sbjct: 1346 TPT--LPATTPSS 1356
Score = 32.3 bits (72), Expect = 2.8
Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 12/102 (11%)
Query: 25 LCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVGSITYDTL 84
L K+ PAT AP+ + P ++ P+P+ +P + P E P P K E S T
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTP---AIPTPKEAPATPSSK--EASSPPAVTP 1587
Query: 85 SAQAQQDGPCTPRRCL----GSLVFPRKLQGRPSPGPPAPEQ 122
S G +P+ L + P++ P+ PP+PE+
Sbjct: 1588 ST---YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626
Score = 32.3 bits (72), Expect = 2.8
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 21/99 (21%)
Query: 31 PATPAPEPSRAPA--SLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVGSITYDTLSAQA 88
PA +P P AP ++ PP+PE +GP P K G+ T ++ +
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPE------------KGPATPAPK----GTPTSPPVTPSS 1646
Query: 89 QQDGPCTPR--RCLGSLVFPRKLQGRPS-PGPPAPEQLL 124
+D P +P C P+ +G P+ GP A +++L
Sbjct: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685
Score = 31.2 bits (69), Expect = 6.2
Identities = 27/97 (27%), Positives = 36/97 (37%), Gaps = 30/97 (30%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVGSITYDTLSAQ 87
K G ATP+P+ + + PP SP P T PP+G P
Sbjct: 1229 KGGLATPSPKGAPTTPAATPP----SPKGGPATPPPKGAPTPPA---------------- 1268
Query: 88 AQQDGPCTPRRCLGSLVFPRKLQGRPSPG---PPAPE 121
TP G L P +G P+P PP+P+
Sbjct: 1269 ------ATPPSLKGGLATPPH-KGAPNPAVVTPPSPK 1298
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 44.7 bits (104), Expect = 5e-04
Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 24/114 (21%)
Query: 27 GKQGPATPAP--EPSRAPASLL--------PPA----PEHSPPSSPLTQPPEGPKFPRVK 72
G P + AP +PS+AP SL+ PPA P+ P + T P P FP
Sbjct: 1098 GSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSP-FPSAT 1156
Query: 73 NWEVGSITYDTLSAQAQQDGPCTPRRCLGSLV------FPRKLQGRPSPGPPAP 120
GS+TY ++ +AQ+ P P++ ++ F GRP P P P
Sbjct: 1157 ---AGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQP 1207
Score = 30.8 bits (68), Expect = 8.1
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 13/90 (14%)
Query: 32 ATPAPEPSRAPASL-LPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVGSITYDTLSAQAQQ 90
ATP +P A A L +PP + +P P GP + S + D+ +AQA
Sbjct: 1522 ATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGP--------DPTSPSSDSGTAQAAP 1573
Query: 91 DGPCTPRRCLGSLVFPRKLQGRPSPGPPAP 120
P P G + +G P P PP P
Sbjct: 1574 PLPPPPESGPGQPGW----EGAPQPSPPPP 1599
>gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3
[Homo sapiens]
Length = 650
Score = 43.1 bits (100), Expect = 0.002
Identities = 31/97 (31%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFP-----RVKNWEVGSITYD 82
+Q P P P P PAS PP P PP +P+ PP GP P R ++T
Sbjct: 377 QQPPPQPQPPPPPPPASQQPPPPP--PPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVP 434
Query: 83 TLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPA 119
+ Q+ + P P + P Q R S G PA
Sbjct: 435 SSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPA 471
>gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1
[Homo sapiens]
Length = 634
Score = 43.1 bits (100), Expect = 0.002
Identities = 31/97 (31%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
Query: 28 KQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFP-----RVKNWEVGSITYD 82
+Q P P P P PAS PP P PP +P+ PP GP P R ++T
Sbjct: 361 QQPPPQPQPPPPPPPASQQPPPPP--PPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVP 418
Query: 83 TLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPA 119
+ Q+ + P P + P Q R S G PA
Sbjct: 419 SSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPA 455
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 42.7 bits (99), Expect = 0.002
Identities = 41/115 (35%), Positives = 49/115 (42%), Gaps = 27/115 (23%)
Query: 8 AQEPGPPCGLGLGLGLGLCGKQGPATP---APEPSRAPASLLPPAPEHSPPSSPLTQPPE 64
A PGP G G G G GPA P P P ++ PP P PP P QPP
Sbjct: 227 ATGPGPGPGPGPGPG------PGPAPPNYSRPHGMGGP-NMPPPGPSGVPPGMP-GQPPG 278
Query: 65 GPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPA 119
GP P W G + +A A TP++ + P + GRPSP PPA
Sbjct: 279 GPPKP----WPEGPMA----NAAAPTS---TPQKLI-----PPQPTGRPSPAPPA 317
Score = 32.7 bits (73), Expect = 2.1
Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 29 QGPATPAPEPSRAPASLLPPAPEHSP-PSSPLTQPPEGPKFP 69
+GP A P+ P L+PP P P P+ P P P P
Sbjct: 286 EGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMP 327
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 42.7 bits (99), Expect = 0.002
Identities = 41/115 (35%), Positives = 49/115 (42%), Gaps = 27/115 (23%)
Query: 8 AQEPGPPCGLGLGLGLGLCGKQGPATP---APEPSRAPASLLPPAPEHSPPSSPLTQPPE 64
A PGP G G G G GPA P P P ++ PP P PP P QPP
Sbjct: 227 ATGPGPGPGPGPGPG------PGPAPPNYSRPHGMGGP-NMPPPGPSGVPPGMP-GQPPG 278
Query: 65 GPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPA 119
GP P W G + +A A TP++ + P + GRPSP PPA
Sbjct: 279 GPPKP----WPEGPMA----NAAAPTS---TPQKLI-----PPQPTGRPSPAPPA 317
Score = 32.7 bits (73), Expect = 2.1
Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 29 QGPATPAPEPSRAPASLLPPAPEHSP-PSSPLTQPPEGPKFP 69
+GP A P+ P L+PP P P P+ P P P P
Sbjct: 286 EGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMP 327
>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform E [Homo sapiens]
Length = 1614
Score = 42.7 bits (99), Expect = 0.002
Identities = 41/115 (35%), Positives = 49/115 (42%), Gaps = 27/115 (23%)
Query: 8 AQEPGPPCGLGLGLGLGLCGKQGPATP---APEPSRAPASLLPPAPEHSPPSSPLTQPPE 64
A PGP G G G G GPA P P P ++ PP P PP P QPP
Sbjct: 227 ATGPGPGPGPGPGPG------PGPAPPNYSRPHGMGGP-NMPPPGPSGVPPGMP-GQPPG 278
Query: 65 GPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPA 119
GP P W G + +A A TP++ + P + GRPSP PPA
Sbjct: 279 GPPKP----WPEGPMA----NAAAPTS---TPQKLI-----PPQPTGRPSPAPPA 317
Score = 32.7 bits (73), Expect = 2.1
Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 29 QGPATPAPEPSRAPASLLPPAPEHSP-PSSPLTQPPEGPKFP 69
+GP A P+ P L+PP P P P+ P P P P
Sbjct: 286 EGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMP 327
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 42.7 bits (99), Expect = 0.002
Identities = 41/115 (35%), Positives = 49/115 (42%), Gaps = 27/115 (23%)
Query: 8 AQEPGPPCGLGLGLGLGLCGKQGPATP---APEPSRAPASLLPPAPEHSPPSSPLTQPPE 64
A PGP G G G G GPA P P P ++ PP P PP P QPP
Sbjct: 227 ATGPGPGPGPGPGPG------PGPAPPNYSRPHGMGGP-NMPPPGPSGVPPGMP-GQPPG 278
Query: 65 GPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPA 119
GP P W G + +A A TP++ + P + GRPSP PPA
Sbjct: 279 GPPKP----WPEGPMA----NAAAPTS---TPQKLI-----PPQPTGRPSPAPPA 317
Score = 32.7 bits (73), Expect = 2.1
Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 29 QGPATPAPEPSRAPASLLPPAPEHSP-PSSPLTQPPEGPKFP 69
+GP A P+ P L+PP P P P+ P P P P
Sbjct: 286 EGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMP 327
>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform C [Homo sapiens]
Length = 1617
Score = 42.7 bits (99), Expect = 0.002
Identities = 41/115 (35%), Positives = 49/115 (42%), Gaps = 27/115 (23%)
Query: 8 AQEPGPPCGLGLGLGLGLCGKQGPATP---APEPSRAPASLLPPAPEHSPPSSPLTQPPE 64
A PGP G G G G GPA P P P ++ PP P PP P QPP
Sbjct: 227 ATGPGPGPGPGPGPG------PGPAPPNYSRPHGMGGP-NMPPPGPSGVPPGMP-GQPPG 278
Query: 65 GPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPA 119
GP P W G + +A A TP++ + P + GRPSP PPA
Sbjct: 279 GPPKP----WPEGPMA----NAAAPTS---TPQKLI-----PPQPTGRPSPAPPA 317
Score = 32.7 bits (73), Expect = 2.1
Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 29 QGPATPAPEPSRAPASLLPPAPEHSP-PSSPLTQPPEGPKFP 69
+GP A P+ P L+PP P P P+ P P P P
Sbjct: 286 EGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMP 327
>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 42.7 bits (99), Expect = 0.002
Identities = 41/115 (35%), Positives = 49/115 (42%), Gaps = 27/115 (23%)
Query: 8 AQEPGPPCGLGLGLGLGLCGKQGPATP---APEPSRAPASLLPPAPEHSPPSSPLTQPPE 64
A PGP G G G G GPA P P P ++ PP P PP P QPP
Sbjct: 227 ATGPGPGPGPGPGPG------PGPAPPNYSRPHGMGGP-NMPPPGPSGVPPGMP-GQPPG 278
Query: 65 GPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPA 119
GP P W G + +A A TP++ + P + GRPSP PPA
Sbjct: 279 GPPKP----WPEGPMA----NAAAPTS---TPQKLI-----PPQPTGRPSPAPPA 317
Score = 32.7 bits (73), Expect = 2.1
Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 29 QGPATPAPEPSRAPASLLPPAPEHSP-PSSPLTQPPEGPKFP 69
+GP A P+ P L+PP P P P+ P P P P
Sbjct: 286 EGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMP 327
>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 42.7 bits (99), Expect = 0.002
Identities = 41/115 (35%), Positives = 49/115 (42%), Gaps = 27/115 (23%)
Query: 8 AQEPGPPCGLGLGLGLGLCGKQGPATP---APEPSRAPASLLPPAPEHSPPSSPLTQPPE 64
A PGP G G G G GPA P P P ++ PP P PP P QPP
Sbjct: 227 ATGPGPGPGPGPGPG------PGPAPPNYSRPHGMGGP-NMPPPGPSGVPPGMP-GQPPG 278
Query: 65 GPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPA 119
GP P W G + +A A TP++ + P + GRPSP PPA
Sbjct: 279 GPPKP----WPEGPMA----NAAAPTS---TPQKLI-----PPQPTGRPSPAPPA 317
Score = 32.7 bits (73), Expect = 2.1
Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 29 QGPATPAPEPSRAPASLLPPAPEHSP-PSSPLTQPPEGPKFP 69
+GP A P+ P L+PP P P P+ P P P P
Sbjct: 286 EGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMP 327
>gi|130502162 RAS protein activator like 3 [Homo sapiens]
Length = 1011
Score = 41.6 bits (96), Expect = 0.005
Identities = 54/206 (26%), Positives = 83/206 (40%), Gaps = 44/206 (21%)
Query: 34 PAPEPSRAP---ASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVGSITY---DTLSAQ 87
P PEP P A L P PE PP+ Q PE P P V W++G T +
Sbjct: 96 PPPEPDPEPEQEAPELEPEPELEPPT---PQIPEAPT-PNVPVWDIGGFTLLDGKLVLLG 151
Query: 88 AQQDGPCTPR-----------RCLGSLVFPRKLQGRPSPGPPAPEQLLSQARDFINQYYS 136
+++GP PR +G+ P ++ G+ P P Q ++
Sbjct: 152 GEEEGPRRPRVGSASSEGSIHVAMGNFRDPDRMPGKTEPETAGPNQ--------VHNVRG 203
Query: 137 SIKRSGSQAHEQRLQEVEAEVAATGTYQ--LRESELVFGAK---QAWRNAPRCVG----- 186
+KR + + RL+ + +A G+ + SEL GA+ + W P +G
Sbjct: 204 LLKRL-KEKKKARLEPRDGPPSALGSRESLATLSELDLGAERDVRIWPLHPSLLGEPHCF 262
Query: 187 RIQW-GKLQVFDARDCRSAQEMFTYI 211
++ W G + F CRSA E +I
Sbjct: 263 QVTWTGGSRCF---SCRSAAERDRWI 285
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 40.0 bits (92), Expect = 0.013
Identities = 32/99 (32%), Positives = 38/99 (38%), Gaps = 12/99 (12%)
Query: 29 QGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVGSITYDTLSAQA 88
+G P P PSRAP + PP P S PS + PP +P L + A
Sbjct: 305 RGRGAPPPPPSRAPTA-APPPPPPSRPSVAVPPPPPNRMYPPPP---------PALPSSA 354
Query: 89 QQDGPCTPRRCL--GSLVFPRKLQGRPSPGPPAPEQLLS 125
P P L G + P P PGPP P L S
Sbjct: 355 PSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPS 393
>gi|4507691 transformation/transcription domain-associated protein
[Homo sapiens]
Length = 3830
Score = 40.0 bits (92), Expect = 0.013
Identities = 17/36 (47%), Positives = 20/36 (55%)
Query: 31 PATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGP 66
PA P P PS AP PP P PP++P+T P P
Sbjct: 491 PAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 39.7 bits (91), Expect = 0.017
Identities = 35/118 (29%), Positives = 42/118 (35%), Gaps = 4/118 (3%)
Query: 8 AQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPE-GP 66
A P PP G P TPAP P AP + PA ++ T PP GP
Sbjct: 106 ATPPAPPRA-PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGP 164
Query: 67 KFPRVKNWEVGSITY--DTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPEQ 122
P + + +A P PRR V R+ P P PPAP Q
Sbjct: 165 AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQ 222
Score = 32.0 bits (71), Expect = 3.6
Identities = 32/130 (24%), Positives = 46/130 (35%), Gaps = 17/130 (13%)
Query: 13 PPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVK 72
PP G + ++ P P P+P P PP P+ PP G P V
Sbjct: 192 PPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARP-VS 250
Query: 73 NWEV-----------GSITYDTLSAQAQQDGPC---TPRRCLGSLVFPRKLQGRPSPGPP 118
EV G +T + +++ R LG+L PR RP PP
Sbjct: 251 LREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPR--GDRPGRAPP 308
Query: 119 APEQLLSQAR 128
A S+++
Sbjct: 309 AASARPSRSK 318
>gi|55741675 hypothetical protein LOC22889 [Homo sapiens]
Length = 614
Score = 39.3 bits (90), Expect = 0.023
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 11/126 (8%)
Query: 11 PGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSP---PSSPLTQPPEGPK 67
P PP G G P P P P S++PPA +P P+ P PP +
Sbjct: 350 PQPPYYPSNGYQSGYPVVPPPQQPVQPPYGVP-SIVPPAVSLAPGVLPALPTGVPPVPTQ 408
Query: 68 FPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPEQLLSQA 127
+P + + + Q+ GP P + + + P Q +P P PP P Q +Q
Sbjct: 409 YP------ITQVQPPASTGQSPMGGPFIPAAPVKTAL-PAGPQPQPQPQPPLPSQPQAQK 461
Query: 128 RDFINQ 133
R F +
Sbjct: 462 RRFTEE 467
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,224,620
Number of Sequences: 37866
Number of extensions: 3058408
Number of successful extensions: 19329
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 339
Number of HSP's that attempted gapping in prelim test: 16030
Number of HSP's gapped (non-prelim): 3150
length of query: 1203
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1089
effective length of database: 13,930,794
effective search space: 15170634666
effective search space used: 15170634666
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.