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Search of human proteins with 40217788
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]
(710 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens] 1414 0.0
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ... 37 0.083
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 35 0.31
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom... 35 0.31
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 35 0.31
gi|7657427 origin recognition complex subunit 6 [Homo sapiens] 32 2.7
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo... 32 2.7
gi|122937247 unc-13 homolog A [Homo sapiens] 31 3.5
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 31 4.5
gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] 31 4.5
gi|56237021 fibrillin 3 precursor [Homo sapiens] 31 4.5
gi|9966865 transient receptor potential cation channel, subfamil... 31 4.5
gi|196123579 NADH dehydrogenase subunit 1 [Homo sapiens neandert... 30 5.9
gi|251831107 NADH dehydrogenase subunit 1 [Homo sapiens] 30 5.9
gi|30089952 protein tyrosine phosphatase domain containing 1 pro... 30 5.9
gi|30089950 protein tyrosine phosphatase domain containing 1 pro... 30 5.9
gi|118402590 myosin XV [Homo sapiens] 30 7.7
>gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]
Length = 710
Score = 1414 bits (3661), Expect = 0.0
Identities = 710/710 (100%), Positives = 710/710 (100%)
Query: 1 MVMACRVVNKRRHMGLQQLSSFAETGRTFLGPLKSSKFIIDEECHESVLISSTVRLLESL 60
MVMACRVVNKRRHMGLQQLSSFAETGRTFLGPLKSSKFIIDEECHESVLISSTVRLLESL
Sbjct: 1 MVMACRVVNKRRHMGLQQLSSFAETGRTFLGPLKSSKFIIDEECHESVLISSTVRLLESL 60
Query: 61 DLTSAVGQLLNEAVQAQNNTYRTGISTLLFLVGAWSSAVEECLHLGVPISIIVSVMSEGL 120
DLTSAVGQLLNEAVQAQNNTYRTGISTLLFLVGAWSSAVEECLHLGVPISIIVSVMSEGL
Sbjct: 61 DLTSAVGQLLNEAVQAQNNTYRTGISTLLFLVGAWSSAVEECLHLGVPISIIVSVMSEGL 120
Query: 121 NFCSEEVVSLHVPVHNIFDCMDSTKTFSQLETFSVSLCPFLQVPSDTDLIEELHGLKDVA 180
NFCSEEVVSLHVPVHNIFDCMDSTKTFSQLETFSVSLCPFLQVPSDTDLIEELHGLKDVA
Sbjct: 121 NFCSEEVVSLHVPVHNIFDCMDSTKTFSQLETFSVSLCPFLQVPSDTDLIEELHGLKDVA 180
Query: 181 SQTLTISNLSGRPLKSYELFKPQTKVEADNNTSRTLKNSLLADTCCRQSILIHSRHFNRT 240
SQTLTISNLSGRPLKSYELFKPQTKVEADNNTSRTLKNSLLADTCCRQSILIHSRHFNRT
Sbjct: 181 SQTLTISNLSGRPLKSYELFKPQTKVEADNNTSRTLKNSLLADTCCRQSILIHSRHFNRT 240
Query: 241 DNTEGVSKPDGFQEHVTATHKTYRCNDLVELAVGLSHGDHSSMKLVEEAVQLQYQNACVQ 300
DNTEGVSKPDGFQEHVTATHKTYRCNDLVELAVGLSHGDHSSMKLVEEAVQLQYQNACVQ
Sbjct: 241 DNTEGVSKPDGFQEHVTATHKTYRCNDLVELAVGLSHGDHSSMKLVEEAVQLQYQNACVQ 300
Query: 301 QGNCTKPFMFDISRIFTCCLPGLPETSSCVCPGYITVVSVSNNPVIKELQNQPVRIVLIE 360
QGNCTKPFMFDISRIFTCCLPGLPETSSCVCPGYITVVSVSNNPVIKELQNQPVRIVLIE
Sbjct: 301 QGNCTKPFMFDISRIFTCCLPGLPETSSCVCPGYITVVSVSNNPVIKELQNQPVRIVLIE 360
Query: 361 GDLTENYRHLGFNKSANIKTVLDSMRLQEDSSEELWANHVLQVLIQFKVNLVLVQGNVSE 420
GDLTENYRHLGFNKSANIKTVLDSMRLQEDSSEELWANHVLQVLIQFKVNLVLVQGNVSE
Sbjct: 361 GDLTENYRHLGFNKSANIKTVLDSMRLQEDSSEELWANHVLQVLIQFKVNLVLVQGNVSE 420
Query: 421 RLIEKCINSKRLVIGSVNGSVMQAFAEAAGAVQVAYITQVNEDCVGDGVCVTFWRSSPLD 480
RLIEKCINSKRLVIGSVNGSVMQAFAEAAGAVQVAYITQVNEDCVGDGVCVTFWRSSPLD
Sbjct: 421 RLIEKCINSKRLVIGSVNGSVMQAFAEAAGAVQVAYITQVNEDCVGDGVCVTFWRSSPLD 480
Query: 481 VVDRNNRIAILLKTEGINLVTAVLTNPVTAQMQIKEDRFWTCAYRLYYALKEEKVFLGGG 540
VVDRNNRIAILLKTEGINLVTAVLTNPVTAQMQIKEDRFWTCAYRLYYALKEEKVFLGGG
Sbjct: 481 VVDRNNRIAILLKTEGINLVTAVLTNPVTAQMQIKEDRFWTCAYRLYYALKEEKVFLGGG 540
Query: 541 AVEFLCLSCLHILAEQSLKKENHACSGWLHNTSSWLASSLAIYRPTVLKFLANGWQKYLS 600
AVEFLCLSCLHILAEQSLKKENHACSGWLHNTSSWLASSLAIYRPTVLKFLANGWQKYLS
Sbjct: 541 AVEFLCLSCLHILAEQSLKKENHACSGWLHNTSSWLASSLAIYRPTVLKFLANGWQKYLS 600
Query: 601 TLLYNTANYSSEFEASTYIQHHLQNATDSGSPSSYILNEYSKLNSRIFNSDISNKLEQIP 660
TLLYNTANYSSEFEASTYIQHHLQNATDSGSPSSYILNEYSKLNSRIFNSDISNKLEQIP
Sbjct: 601 TLLYNTANYSSEFEASTYIQHHLQNATDSGSPSSYILNEYSKLNSRIFNSDISNKLEQIP 660
Query: 661 RVYDVVTPKIEAWRRALDLVLLVLQTDSEIITGHGHTQINSQELTGFLFL 710
RVYDVVTPKIEAWRRALDLVLLVLQTDSEIITGHGHTQINSQELTGFLFL
Sbjct: 661 RVYDVVTPKIEAWRRALDLVLLVLQTDSEIITGHGHTQINSQELTGFLFL 710
>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
sapiens]
Length = 548
Score = 36.6 bits (83), Expect = 0.083
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Query: 13 HMGLQQLSSFAETGRTFLGPLKSSKFIIDEECHESVLISSTVRLLESLDLTSAVGQLLNE 72
+ +Q A+T RT GP +K +I+ + + + +L L++ +++
Sbjct: 30 YRNIQACKELAQTTRTAYGPNGMNKMVIN-HLEKLFVTNDAATILRELEVQHPAAKMIVM 88
Query: 73 AVQAQNNTYRTGISTLLFLVGAWSSAVEECLHLGVPISIIV 113
A Q G + +L GA EE L +G+ +S ++
Sbjct: 89 ASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVI 129
>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
sapiens]
Length = 544
Score = 34.7 bits (78), Expect = 0.31
Identities = 36/149 (24%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 320 LPGLPETSSCVCPGYITVVSVSNNPVIKELQNQPVRIVLIEGDLTENYRHLGFNKSANIK 379
+PG SCV G + V++ + + ++N RIVL++ L Y+ I
Sbjct: 203 IPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNP--RIVLLDSSL--EYKKGESQTDIEIT 258
Query: 380 TVLDSMRLQEDSSEELWANHVLQVLIQFKVNLVLVQGNVSERLIEKCINSKRLVIGSVNG 439
D R+ + EE + + + +IQ K ++V+ + +S+ + + I V
Sbjct: 259 REEDFTRILQ--MEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRK 316
Query: 440 SVMQAFAEAAGAVQVAYITQVNEDCVGDG 468
+ A A GA V+ ++ ED VG G
Sbjct: 317 TDNNRIARACGARIVSRPEELREDDVGTG 345
>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
sapiens]
Length = 507
Score = 34.7 bits (78), Expect = 0.31
Identities = 36/149 (24%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 320 LPGLPETSSCVCPGYITVVSVSNNPVIKELQNQPVRIVLIEGDLTENYRHLGFNKSANIK 379
+PG SCV G + V++ + + ++N RIVL++ L Y+ I
Sbjct: 166 IPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNP--RIVLLDSSL--EYKKGESQTDIEIT 221
Query: 380 TVLDSMRLQEDSSEELWANHVLQVLIQFKVNLVLVQGNVSERLIEKCINSKRLVIGSVNG 439
D R+ + EE + + + +IQ K ++V+ + +S+ + + I V
Sbjct: 222 REEDFTRILQ--MEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRK 279
Query: 440 SVMQAFAEAAGAVQVAYITQVNEDCVGDG 468
+ A A GA V+ ++ ED VG G
Sbjct: 280 TDNNRIARACGARIVSRPEELREDDVGTG 308
>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
sapiens]
Length = 545
Score = 34.7 bits (78), Expect = 0.31
Identities = 36/149 (24%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 320 LPGLPETSSCVCPGYITVVSVSNNPVIKELQNQPVRIVLIEGDLTENYRHLGFNKSANIK 379
+PG SCV G + V++ + + ++N RIVL++ L Y+ I
Sbjct: 204 IPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNP--RIVLLDSSL--EYKKGESQTDIEIT 259
Query: 380 TVLDSMRLQEDSSEELWANHVLQVLIQFKVNLVLVQGNVSERLIEKCINSKRLVIGSVNG 439
D R+ + EE + + + +IQ K ++V+ + +S+ + + I V
Sbjct: 260 REEDFTRILQ--MEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRK 317
Query: 440 SVMQAFAEAAGAVQVAYITQVNEDCVGDG 468
+ A A GA V+ ++ ED VG G
Sbjct: 318 TDNNRIARACGARIVSRPEELREDDVGTG 346
>gi|7657427 origin recognition complex subunit 6 [Homo sapiens]
Length = 252
Score = 31.6 bits (70), Expect = 2.7
Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 175 GLKDVASQTLTIS--NLSGRPLKSYELFKPQTKVEADNNTSRTLKNSLLADTCCRQSILI 232
G++D+A Q I N++ + LKSYE PQT+ + D + SR L S + C+ IL
Sbjct: 97 GIRDLAVQFSCIEAVNMASKILKSYESSLPQTQ-QVDLDLSRPLFTSAALLSACK--ILK 153
Query: 233 HSRHFNRTDNTEGVSK 248
N+ T GV K
Sbjct: 154 LKVDKNKMVATSGVKK 169
>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
sapiens]
Length = 543
Score = 31.6 bits (70), Expect = 2.7
Identities = 44/200 (22%), Positives = 79/200 (39%), Gaps = 19/200 (9%)
Query: 23 AETGRTFLGPLKSSKFIIDEECHESVLISSTVRLLESLDLTSAVGQLLNEAVQAQNNTYR 82
AE RT LGP K I+D ++ + + +L+ LD+ + L + ++Q+
Sbjct: 33 AEAVRTTLGPRGMDKLIVDGR-GKATISNDGATILKLLDVVHPAAKTLVDIAKSQDAEVG 91
Query: 83 TGISTLLFLVGAWSSAVEECLHLGVPISIIVSVMSEGLNFCSEEVVSLHVPVHNIFDCMD 142
G +++ L + V+ + G+ II+ ++ + V V D ++
Sbjct: 92 DGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAVTVKKA-DKVE 150
Query: 143 -------------STKTFSQLETFSVSLCPFLQVPSDTDLIEELHGLKDVASQTLTISNL 189
S+K SQ + F + + D L ++ G+K V L S L
Sbjct: 151 QRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQLKMIGIKKVQGGALEDSQL 210
Query: 190 -SGRPLK---SYELFKPQTK 205
+G K SY F+ Q K
Sbjct: 211 VAGVAFKKTFSYAGFEMQPK 230
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 31.2 bits (69), Expect = 3.5
Identities = 15/62 (24%), Positives = 29/62 (46%)
Query: 631 SPSSYILNEYSKLNSRIFNSDISNKLEQIPRVYDVVTPKIEAWRRALDLVLLVLQTDSEI 690
S YI N +L SR + +D + K E +P ++ W + + L++ +++ D
Sbjct: 1094 STYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGPSIKNLDFWSKLITLIVSIIEEDKNS 1153
Query: 691 IT 692
T
Sbjct: 1154 YT 1155
>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
Length = 588
Score = 30.8 bits (68), Expect = 4.5
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 4/86 (4%)
Query: 133 PVHNIFDCMDSTKTFSQLETFSVSLCPFLQVPSDTDLIEELHGLKDVASQTLTISNLSGR 192
P N T T S+ SV +++ + L G DV QT+TIS + GR
Sbjct: 255 PSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAIDVIGQTITISRVEGR 314
Query: 193 ----PLKSYELFKPQTKVEADNNTSR 214
+ ++ ++ E DNN S+
Sbjct: 315 RRANENSNIQVLSERSATEVDNNFSK 340
>gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]
Length = 594
Score = 30.8 bits (68), Expect = 4.5
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 4/86 (4%)
Query: 133 PVHNIFDCMDSTKTFSQLETFSVSLCPFLQVPSDTDLIEELHGLKDVASQTLTISNLSGR 192
P N T T S+ SV +++ + L G DV QT+TIS + GR
Sbjct: 270 PSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAIDVIGQTITISRVEGR 329
Query: 193 ----PLKSYELFKPQTKVEADNNTSR 214
+ ++ ++ E DNN S+
Sbjct: 330 RRANENSNIQVLSERSATEVDNNFSK 355
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 30.8 bits (68), Expect = 4.5
Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 12/68 (17%)
Query: 255 HVTATHKTYRCNDLVELAVGLSHGDHSSMKLVEEAVQLQYQNAC---VQQGNCTKPFMFD 311
H T T ++RC L LAVG V ++ C +++G+C +PF
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDG---------RVCVDTHVRSTCYGAIEKGSCARPFPGT 636
Query: 312 ISRIFTCC 319
+++ CC
Sbjct: 637 VTKSECCC 644
>gi|9966865 transient receptor potential cation channel, subfamily
C, member 7 [Homo sapiens]
Length = 862
Score = 30.8 bits (68), Expect = 4.5
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 341 SNNPVIK--ELQNQPVRIVLIEGDLTENYRHLGFNKSANIKTVLDSMR--------LQED 390
S +PV+ EL N+ R+ IE + +YR L + VLD R L D
Sbjct: 235 SEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGD 294
Query: 391 SSEELWANH------VLQVLIQFKVNLVLVQGNVSERLI 423
+ ++W++H +++ I+++V + N ++L+
Sbjct: 295 VNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLL 333
>gi|196123579 NADH dehydrogenase subunit 1 [Homo sapiens
neanderthalensis]
Length = 318
Score = 30.4 bits (67), Expect = 5.9
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 545 LCLSCLHILAEQSLKKENHACSGWLHNTSSWLASSLAIYRPTVLKFLANGWQKYLSTLLY 604
L L L ILA SL + SGW N++ L +L T+ ++ L+ +L
Sbjct: 98 LNLGLLFILATSSLAVYSILWSGWASNSNYALIGALRAVAQTI------SYEVTLAIILL 151
Query: 605 NTANYSSEFEASTYI--QHHL 623
+T S F ST I Q HL
Sbjct: 152 STLLMSGSFNLSTLITAQEHL 172
>gi|251831107 NADH dehydrogenase subunit 1 [Homo sapiens]
Length = 318
Score = 30.4 bits (67), Expect = 5.9
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 545 LCLSCLHILAEQSLKKENHACSGWLHNTSSWLASSLAIYRPTVLKFLANGWQKYLSTLLY 604
L L L ILA SL + SGW N++ L +L T+ ++ L+ +L
Sbjct: 98 LNLGLLFILATSSLAVYSILWSGWASNSNYALIGALRAVAQTI------SYEVTLAIILL 151
Query: 605 NTANYSSEFEASTYI--QHHL 623
+T S F ST I Q HL
Sbjct: 152 STLLMSGSFNLSTLITTQEHL 172
>gi|30089952 protein tyrosine phosphatase domain containing 1
protein isoform 1 [Homo sapiens]
Length = 806
Score = 30.4 bits (67), Expect = 5.9
Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 1/93 (1%)
Query: 50 ISSTVRLLESLDLTSAVGQLLNEAVQAQNNTYRTGISTLLFLVGAWSSAVEECLHLGVPI 109
++S +L+ + + + Q A+ RTG+ +LV A ++ + + V
Sbjct: 216 VASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAI-IFVRA 274
Query: 110 SIIVSVMSEGLNFCSEEVVSLHVPVHNIFDCMD 142
S+ + G C E P+ NIF C D
Sbjct: 275 KRPNSIQTRGQLLCVREFTQFLTPLRNIFSCCD 307
>gi|30089950 protein tyrosine phosphatase domain containing 1
protein isoform 2 [Homo sapiens]
Length = 754
Score = 30.4 bits (67), Expect = 5.9
Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 1/93 (1%)
Query: 50 ISSTVRLLESLDLTSAVGQLLNEAVQAQNNTYRTGISTLLFLVGAWSSAVEECLHLGVPI 109
++S +L+ + + + Q A+ RTG+ +LV A ++ + + V
Sbjct: 164 VASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAI-IFVRA 222
Query: 110 SIIVSVMSEGLNFCSEEVVSLHVPVHNIFDCMD 142
S+ + G C E P+ NIF C D
Sbjct: 223 KRPNSIQTRGQLLCVREFTQFLTPLRNIFSCCD 255
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 30.0 bits (66), Expect = 7.7
Identities = 15/49 (30%), Positives = 26/49 (53%)
Query: 84 GISTLLFLVGAWSSAVEECLHLGVPISIIVSVMSEGLNFCSEEVVSLHV 132
G+ + L + G+ ++ C ++ VP I+++ GLNF S E L V
Sbjct: 3406 GLLSALPMFGSSFFFIQSCSNIAVPAPCILAINHNGLNFLSTETHELMV 3454
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,790,230
Number of Sequences: 37866
Number of extensions: 1033647
Number of successful extensions: 2444
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2436
Number of HSP's gapped (non-prelim): 22
length of query: 710
length of database: 18,247,518
effective HSP length: 109
effective length of query: 601
effective length of database: 14,120,124
effective search space: 8486194524
effective search space used: 8486194524
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.