Search of human proteins with 40068479

Search of human proteins with 40068479

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40068479 mitochondrial rRNA methyltransferase 1 homolog
[Homo sapiens]
         (353 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40068479 mitochondrial rRNA methyltransferase 1 homolog [Homo...   706   0.0  
gi|8922534 RNA methyltransferase like 1 [Homo sapiens]                 43   5e-04
gi|199560438 hypothetical protein LOC283643 isoform 2 [Homo sapi...    31   1.9  
gi|199560355 hypothetical protein LOC283643 isoform 1 [Homo sapi...    31   1.9  
gi|41327754 ankyrin repeat domain 3 [Homo sapiens]                     31   1.9  
gi|12232389 methyltransferase 11 domain containing 1 isoform 2 [...    30   2.5  
gi|71999135 methyltransferase 11 domain containing 1 isoform 1 [...    30   2.5  
gi|199560536 hypothetical protein LOC283643 isoform 4 [Homo sapi...    30   2.5  
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                       30   4.3  
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                        30   4.3  
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         30   4.3  
gi|126723390 ankyrin repeat domain 24 [Homo sapiens]                   30   4.3  
gi|7656938 CREBBP/EP300 inhibitor 1 [Homo sapiens]                     28   9.5  
gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]      28   9.5  
gi|148596992 heart alpha-kinase [Homo sapiens]                         28   9.5  

>gi|40068479 mitochondrial rRNA methyltransferase 1 homolog [Homo
           sapiens]
          Length = 353

 Score =  706 bits (1821), Expect = 0.0
 Identities = 353/353 (100%), Positives = 353/353 (100%)

Query: 1   MALLSTVRGATWGRLVTRHFSHAARHGERPGGEELSRLLLDDLVPTSRLELLFGMTPCLL 60
           MALLSTVRGATWGRLVTRHFSHAARHGERPGGEELSRLLLDDLVPTSRLELLFGMTPCLL
Sbjct: 1   MALLSTVRGATWGRLVTRHFSHAARHGERPGGEELSRLLLDDLVPTSRLELLFGMTPCLL 60

Query: 61  ALQAARRSVARLLLQAGKAGLQGKRAELLRMAEARDIPVLRPRRQKLDTMCRYQVHQGVC 120
           ALQAARRSVARLLLQAGKAGLQGKRAELLRMAEARDIPVLRPRRQKLDTMCRYQVHQGVC
Sbjct: 61  ALQAARRSVARLLLQAGKAGLQGKRAELLRMAEARDIPVLRPRRQKLDTMCRYQVHQGVC 120

Query: 121 MEVSPLRPRPWREAGEASPGDDPQQLWLVLDGIQDPRNFGAVLRSAHFLGVDKVITSRRN 180
           MEVSPLRPRPWREAGEASPGDDPQQLWLVLDGIQDPRNFGAVLRSAHFLGVDKVITSRRN
Sbjct: 121 MEVSPLRPRPWREAGEASPGDDPQQLWLVLDGIQDPRNFGAVLRSAHFLGVDKVITSRRN 180

Query: 181 SCPLTPVVSKSSAGAMEVMDVFSTDDLTGFLQTKAQQGWLVAGTVGCPSTEDPQSSEIPI 240
           SCPLTPVVSKSSAGAMEVMDVFSTDDLTGFLQTKAQQGWLVAGTVGCPSTEDPQSSEIPI
Sbjct: 181 SCPLTPVVSKSSAGAMEVMDVFSTDDLTGFLQTKAQQGWLVAGTVGCPSTEDPQSSEIPI 240

Query: 241 MSCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPRRQLPPGLESLNVSVAAGILL 300
           MSCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPRRQLPPGLESLNVSVAAGILL
Sbjct: 241 MSCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPRRQLPPGLESLNVSVAAGILL 300

Query: 301 HSICSQRKGFPTEGERRQLLQDPQEPSARSEGLSMAQHPGLSSGPEKERQNEG 353
           HSICSQRKGFPTEGERRQLLQDPQEPSARSEGLSMAQHPGLSSGPEKERQNEG
Sbjct: 301 HSICSQRKGFPTEGERRQLLQDPQEPSARSEGLSMAQHPGLSSGPEKERQNEG 353


>gi|8922534 RNA methyltransferase like 1 [Homo sapiens]
          Length = 420

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 53/202 (26%), Positives = 85/202 (42%), Gaps = 41/202 (20%)

Query: 146 LWLVLDGIQDPRNFGAVLRSAHFLGVDKVITSRRNSCPLTPVVSKSSAGA---MEVMD-- 200
           L L+ D ++DP N G +LRSA   G  KV+ ++       P V ++  GA   M +++  
Sbjct: 210 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNL 269

Query: 201 --------------VFSTDDLTGFLQTK-----AQQGWLVAGTV----GCPSTEDPQSS- 236
                         V+  D+   + Q +     +  GW+    V         ED ++  
Sbjct: 270 EWETVPNYLPPDTRVYVADNCGLYAQAEMSNKASDHGWVCDQRVMKFHKYEEEEDVETGA 329

Query: 237 ------EIPIMSCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPRRQL---PPGL 287
                  + + S      E P  +V+G E  G+S E   S QL  +   +R L    PG+
Sbjct: 330 SQDWLPHVEVQSYDSDWTEAPAAVVIGGETYGVSLE---SLQLAESTGGKRLLIPVVPGV 386

Query: 288 ESLNVSVAAGILLHSICSQRKG 309
           +SLN ++AA ILL     Q +G
Sbjct: 387 DSLNSAMAASILLFEGKRQLRG 408


>gi|199560438 hypothetical protein LOC283643 isoform 2 [Homo
           sapiens]
          Length = 393

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 265 QEVQASCQLLLTILPRRQLPPGLESLNVSVAAGILLHSICSQRKGFPTEGERRQLLQDPQ 324
           +   A  QLL  +L        L SL + V A ++  ++CSQ  G+P    R  L Q P+
Sbjct: 48  EATSALWQLLFRVLSPLPAGNALASLALEVQARLVKSALCSQ--GYP----RLALAQLPE 101

Query: 325 EPSARSEGLSMAQHPGLSSGPEKER 349
           + S  S  L +A    L+ GP  E+
Sbjct: 102 DGSQGSRELLLALSWLLARGPVPEQ 126


>gi|199560355 hypothetical protein LOC283643 isoform 1 [Homo
           sapiens]
          Length = 426

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 265 QEVQASCQLLLTILPRRQLPPGLESLNVSVAAGILLHSICSQRKGFPTEGERRQLLQDPQ 324
           +   A  QLL  +L        L SL + V A ++  ++CSQ  G+P    R  L Q P+
Sbjct: 48  EATSALWQLLFRVLSPLPAGNALASLALEVQARLVKSALCSQ--GYP----RLALAQLPE 101

Query: 325 EPSARSEGLSMAQHPGLSSGPEKER 349
           + S  S  L +A    L+ GP  E+
Sbjct: 102 DGSQGSRELLLALSWLLARGPVPEQ 126


>gi|41327754 ankyrin repeat domain 3 [Homo sapiens]
          Length = 784

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 2/59 (3%)

Query: 31  GGEELSRLLLDDLVPTSRLELLFGMTPCLLALQAARRSVARLLLQAG-KAGLQGKRAEL 88
           G E  +RLLL+     + ++   G TP  +A Q  + ++ R+LL+ G    LQGK A L
Sbjct: 515 GDESSTRLLLEKNASVNEVDFE-GRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWL 572


>gi|12232389 methyltransferase 11 domain containing 1 isoform 2
           [Homo sapiens]
          Length = 456

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 17/109 (15%)

Query: 182 CPLTPVVSKSSAGAMEVMDVFSTDDLTGFLQTKAQQGWLVAGTVGCPSTEDPQSSEIPIM 241
           CP   V  ++ A A  V  V   D+ +GFLQ +             P  + P   ++P +
Sbjct: 15  CPGLGVAPQARALAALVPGVTQVDNKSGFLQKR-------------PHRQHPGILKLPHV 61

Query: 242 SCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPRRQLPPGLESL 290
              + L     LL+LG+ G  +  +VQ     L + L  R LP   E L
Sbjct: 62  RLPQALANGAQLLLLGSAGPTMENQVQT----LTSYLWSRHLPVEPEEL 106


>gi|71999135 methyltransferase 11 domain containing 1 isoform 1
           [Homo sapiens]
          Length = 478

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 17/109 (15%)

Query: 182 CPLTPVVSKSSAGAMEVMDVFSTDDLTGFLQTKAQQGWLVAGTVGCPSTEDPQSSEIPIM 241
           CP   V  ++ A A  V  V   D+ +GFLQ +             P  + P   ++P +
Sbjct: 15  CPGLGVAPQARALAALVPGVTQVDNKSGFLQKR-------------PHRQHPGILKLPHV 61

Query: 242 SCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPRRQLPPGLESL 290
              + L     LL+LG+ G  +  +VQ     L + L  R LP   E L
Sbjct: 62  RLPQALANGAQLLLLGSAGPTMENQVQT----LTSYLWSRHLPVEPEEL 106


>gi|199560536 hypothetical protein LOC283643 isoform 4 [Homo
           sapiens]
          Length = 352

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 6/78 (7%)

Query: 272 QLLLTILPRRQLPPGLESLNVSVAAGILLHSICSQRKGFPTEGERRQLLQDPQEPSARSE 331
           QLL  +L        L SL + V A ++  ++CSQ  G+P    R  L Q P++ S  S 
Sbjct: 14  QLLFRVLSPLPAGNALASLALEVQARLVKSALCSQ--GYP----RLALAQLPEDGSQGSR 67

Query: 332 GLSMAQHPGLSSGPEKER 349
            L +A    L+ GP  E+
Sbjct: 68  ELLLALSWLLARGPVPEQ 85


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 37/155 (23%), Positives = 65/155 (41%), Gaps = 21/155 (13%)

Query: 16  VTRHFSHAARHGERPGGEELSRLLLDDLVP------TSRLELLFGMTPCLLALQAARRSV 69
           + +HF+   ++  +   E+    +  D+V       +S +  L GM P  +   A  R+ 
Sbjct: 632 IIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAVFRWAVLRAA 691

Query: 70  ARLLLQAGKAG-LQGKRAEL---LRMAEARDIPVLRPRRQKLDTMCRYQ-VHQGVCMEVS 124
            R +    +AG L+ +RAE    +    A+  P   PR     +   Y+ +H  +   + 
Sbjct: 692 IRAMAVLREAGRLRAERAEKAAGMSSPGAQSHPEELPRGASTPSEKLYRDLHNQMIKSIK 751

Query: 125 PLRPRPWREAGEASPGDDPQQLWLVLDGIQDPRNF 159
            L   PW+       G+DP+ L   L  +Q PR F
Sbjct: 752 GL---PWQ-------GEDPRSLLQSLSRLQKPRAF 776


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 37/155 (23%), Positives = 65/155 (41%), Gaps = 21/155 (13%)

Query: 16  VTRHFSHAARHGERPGGEELSRLLLDDLVP------TSRLELLFGMTPCLLALQAARRSV 69
           + +HF+   ++  +   E+    +  D+V       +S +  L GM P  +   A  R+ 
Sbjct: 632 IIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAVFRWAVLRAA 691

Query: 70  ARLLLQAGKAG-LQGKRAEL---LRMAEARDIPVLRPRRQKLDTMCRYQ-VHQGVCMEVS 124
            R +    +AG L+ +RAE    +    A+  P   PR     +   Y+ +H  +   + 
Sbjct: 692 IRAMAVLREAGRLRAERAEKAAGMSSPGAQSHPEELPRGASTPSEKLYRDLHNQMIKSIK 751

Query: 125 PLRPRPWREAGEASPGDDPQQLWLVLDGIQDPRNF 159
            L   PW+       G+DP+ L   L  +Q PR F
Sbjct: 752 GL---PWQ-------GEDPRSLLQSLSRLQKPRAF 776


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 7/93 (7%)

Query: 58  CLLALQAARRSVA------RLLLQAGKAGLQGKRAELLRMAEARDIPVLRPRRQKLDTMC 111
           C+  L+A  RS+       R  L+  +AG +G  A L ++ EA        RR+  + M 
Sbjct: 735 CISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMA 794

Query: 112 RYQVHQGVCMEVSPLRPRPWREAGEASPGDDPQ 144
                +  C ++       WRE  E S  ++ Q
Sbjct: 795 AQHTAESECEQLVK-EVAAWRERYEDSQQEEAQ 826


>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
          Length = 1146

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 4/40 (10%)

Query: 54  GMTPCLLALQAARRSVARLLLQAGKAG----LQGKRAELL 89
           G TP ++A Q     + RLLLQ G A     LQG+ A +L
Sbjct: 181 GATPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALML 220


>gi|7656938 CREBBP/EP300 inhibitor 1 [Homo sapiens]
          Length = 187

 Score = 28.5 bits (62), Expect = 9.5
 Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 12/103 (11%)

Query: 258 NEGSGLSQEVQASCQLLLTILPRRQLPPGLESLNVSVAAGILLHSICSQRKGF------- 310
           +E + LS+  + S  L + ++P     P +E     V +G    S+   R G        
Sbjct: 2   SEMAELSELYEESSDLQMDVMPGEGDLPQME-----VGSGSRELSLRPSRSGAQQLEEEG 56

Query: 311 PTEGERRQLLQDPQEPSARSEGLSMAQHPGLSSGPEKERQNEG 353
           P E E  Q +  P+   + + G +  + PG  +G + E ++EG
Sbjct: 57  PMEEEEAQPMAAPEGKRSLANGPNAGEQPGQVAGADFESEDEG 99


>gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]
          Length = 1992

 Score = 28.5 bits (62), Expect = 9.5
 Identities = 14/47 (29%), Positives = 23/47 (48%)

Query: 2    ALLSTVRGATWGRLVTRHFSHAARHGERPGGEELSRLLLDDLVPTSR 48
            + L+++   TWGRL T+  S+        GG  L+R    D +  +R
Sbjct: 1040 SFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKDTISNNR 1086


>gi|148596992 heart alpha-kinase [Homo sapiens]
          Length = 2170

 Score = 28.5 bits (62), Expect = 9.5
 Identities = 13/41 (31%), Positives = 20/41 (48%)

Query: 228  PSTEDPQSSEIPIMSCLEFLWERPTLLVLGNEGSGLSQEVQ 268
            PS  D  ++     S + F WE+PT L   NE    ++E +
Sbjct: 966  PSAADTTATPASYSSIVSFPWEKPTTLTANNECFQATRETE 1006


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,715,042
Number of Sequences: 37866
Number of extensions: 687570
Number of successful extensions: 1842
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1830
Number of HSP's gapped (non-prelim): 22
length of query: 353
length of database: 18,247,518
effective HSP length: 103
effective length of query: 250
effective length of database: 14,347,320
effective search space: 3586830000
effective search space used: 3586830000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.