Guide to the Human Genome
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Search of human proteins with 38570146

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38570146 synaptotagmin VII [Homo sapiens]
         (403 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38570146 synaptotagmin VII [Homo sapiens]                          818   0.0  
gi|211059429 synaptotagmin II [Homo sapiens]                          294   1e-79
gi|31543670 synaptotagmin II [Homo sapiens]                           294   1e-79
gi|209447073 synaptotagmin I [Homo sapiens]                           290   2e-78
gi|5032139 synaptotagmin I [Homo sapiens]                             290   2e-78
gi|209447070 synaptotagmin I [Homo sapiens]                           290   2e-78
gi|92859638 synaptotagmin V [Homo sapiens]                            268   8e-72
gi|45504376 synaptotagmin VI [Homo sapiens]                           261   6e-70
gi|39752671 synaptotagmin X [Homo sapiens]                            251   8e-67
gi|28376627 synaptotagmin IX [Homo sapiens]                           247   1e-65
gi|24308219 synaptotagmin IV [Homo sapiens]                           233   3e-61
gi|238550198 synaptotagmin III [Homo sapiens]                         231   9e-61
gi|238550196 synaptotagmin III [Homo sapiens]                         231   9e-61
gi|14150054 synaptotagmin III [Homo sapiens]                          231   9e-61
gi|216548478 synaptotagmin XI [Homo sapiens]                          228   6e-60
gi|40068038 B/K protein [Homo sapiens]                                213   2e-55
gi|47078261 double C2-like domains, alpha [Homo sapiens]              178   9e-45
gi|6005997 double C2-like domains, beta [Homo sapiens]                176   4e-44
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            172   5e-43
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             172   5e-43
gi|94536846 synaptotagmin VIII [Homo sapiens]                         161   1e-39
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                 153   3e-37
gi|29366828 synaptotagmin XII [Homo sapiens]                          138   1e-32
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      131   9e-31
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      131   9e-31
gi|31881667 synaptotagmin XV isoform b [Homo sapiens]                 131   1e-30
gi|24308233 synaptotagmin XIII [Homo sapiens]                         124   2e-28
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap...   115   9e-26
gi|14249614 synaptotagmin-like 1 [Homo sapiens]                       115   9e-26
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]               104   2e-22

>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  818 bits (2112), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MYRDPEAASPGAPSRDVLLVSAIITVSLSVTVVLCGLCHWCQRKLGKRYKNSLETVGTPD 60
           MYRDPEAASPGAPSRDVLLVSAIITVSLSVTVVLCGLCHWCQRKLGKRYKNSLETVGTPD
Sbjct: 1   MYRDPEAASPGAPSRDVLLVSAIITVSLSVTVVLCGLCHWCQRKLGKRYKNSLETVGTPD 60

Query: 61  SGRGRSEKKAIKLPAGGKAVNTAPVPGQTPHDESDRRTEPRSSVSDLVNSLTSEMLMLSP 120
           SGRGRSEKKAIKLPAGGKAVNTAPVPGQTPHDESDRRTEPRSSVSDLVNSLTSEMLMLSP
Sbjct: 61  SGRGRSEKKAIKLPAGGKAVNTAPVPGQTPHDESDRRTEPRSSVSDLVNSLTSEMLMLSP 120

Query: 121 GSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLL 180
           GSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLL
Sbjct: 121 GSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLL 180

Query: 181 PDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSI 240
           PDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSI
Sbjct: 181 PDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSI 240

Query: 241 PLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGG 300
           PLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGG
Sbjct: 241 PLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGG 300

Query: 301 TSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDK 360
           TSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDK
Sbjct: 301 TSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDK 360

Query: 361 LSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLKA 403
           LSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLKA
Sbjct: 361 LSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLKA 403


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  294 bits (752), Expect = 1e-79
 Identities = 141/280 (50%), Positives = 200/280 (71%), Gaps = 2/280 (0%)

Query: 124 EDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDK 183
           E E  E    ENLG++QFS+ Y+FQ + LTV +++A ELPA D  GTSDP+VK++LLPDK
Sbjct: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187

Query: 184 KHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLN 243
           K K ETKV RK LNP +NETF F+  PY+++  + L + + D+DRFS++D IGEV +P+N
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246

Query: 244 KVDLTQMQTFWKDLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTS 302
            VDL Q    W+DL+        + G++  SL Y P+A  + V I++A+NLK MD+GG S
Sbjct: 247 TVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLS 306

Query: 303 DPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLS 362
           DPYVK+ LM   KR++KKKT   K+ LNP FNESF+F+IP E++++  +++TV+D DKL 
Sbjct: 307 DPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLG 366

Query: 363 RNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLK 402
           +N+ IGKI++   +   E++HW DM+A PR+P+AQWH LK
Sbjct: 367 KNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLK 406


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  294 bits (752), Expect = 1e-79
 Identities = 141/280 (50%), Positives = 200/280 (71%), Gaps = 2/280 (0%)

Query: 124 EDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDK 183
           E E  E    ENLG++QFS+ Y+FQ + LTV +++A ELPA D  GTSDP+VK++LLPDK
Sbjct: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187

Query: 184 KHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLN 243
           K K ETKV RK LNP +NETF F+  PY+++  + L + + D+DRFS++D IGEV +P+N
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246

Query: 244 KVDLTQMQTFWKDLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTS 302
            VDL Q    W+DL+        + G++  SL Y P+A  + V I++A+NLK MD+GG S
Sbjct: 247 TVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLS 306

Query: 303 DPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLS 362
           DPYVK+ LM   KR++KKKT   K+ LNP FNESF+F+IP E++++  +++TV+D DKL 
Sbjct: 307 DPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLG 366

Query: 363 RNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLK 402
           +N+ IGKI++   +   E++HW DM+A PR+P+AQWH LK
Sbjct: 367 KNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLK 406


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  290 bits (742), Expect = 2e-78
 Identities = 155/388 (39%), Positives = 232/388 (59%), Gaps = 42/388 (10%)

Query: 18  LLVSAIITVSLSVTVVLCGLCHWCQRKLGKRYKNSLETVGTPDSGRGRSEKKAIKLPAGG 77
           L+  AI+ V L +T   C +C  C  K                    +  KK  K   G 
Sbjct: 61  LIAIAIVAVLLVLTCCFC-ICKKCLFK--------------------KKNKKKGKEKGGK 99

Query: 78  KAVNTAPVP--GQTPHDESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSREN 135
            A+N   V   G+T  D++ +  +  + ++D              G E++E  E    E 
Sbjct: 100 NAINMKDVKDLGKTMKDQALKDDDAETGLTD--------------GEEKEEPKE---EEK 142

Query: 136 LGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKN 195
           LG++Q+S+ Y+FQ + L V I++A ELPA D  GTSDP+VK++LLPDKK K ETKV RK 
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 202

Query: 196 LNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWK 255
           LNP +NE F F+  PY ++  + L + V D+DRFS++D IGE  +P+N VD   +   W+
Sbjct: 203 LNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWR 261

Query: 256 DLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKD 314
           DL+        + G++  SL Y P+A  + V I++A+NLK MD+GG SDPYVK+ LM   
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321

Query: 315 KRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSW 374
           KR++KKKT   K  LNP +NESF+F++P E++++  +++TV+D DK+ +ND IGK+++ +
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381

Query: 375 KSGPGEVKHWKDMIARPRQPVAQWHQLK 402
            S   E++HW DM+A PR+P+AQWH L+
Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQ 409


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  290 bits (742), Expect = 2e-78
 Identities = 155/388 (39%), Positives = 232/388 (59%), Gaps = 42/388 (10%)

Query: 18  LLVSAIITVSLSVTVVLCGLCHWCQRKLGKRYKNSLETVGTPDSGRGRSEKKAIKLPAGG 77
           L+  AI+ V L +T   C +C  C  K                    +  KK  K   G 
Sbjct: 61  LIAIAIVAVLLVLTCCFC-ICKKCLFK--------------------KKNKKKGKEKGGK 99

Query: 78  KAVNTAPVP--GQTPHDESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSREN 135
            A+N   V   G+T  D++ +  +  + ++D              G E++E  E    E 
Sbjct: 100 NAINMKDVKDLGKTMKDQALKDDDAETGLTD--------------GEEKEEPKE---EEK 142

Query: 136 LGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKN 195
           LG++Q+S+ Y+FQ + L V I++A ELPA D  GTSDP+VK++LLPDKK K ETKV RK 
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 202

Query: 196 LNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWK 255
           LNP +NE F F+  PY ++  + L + V D+DRFS++D IGE  +P+N VD   +   W+
Sbjct: 203 LNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWR 261

Query: 256 DLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKD 314
           DL+        + G++  SL Y P+A  + V I++A+NLK MD+GG SDPYVK+ LM   
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321

Query: 315 KRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSW 374
           KR++KKKT   K  LNP +NESF+F++P E++++  +++TV+D DK+ +ND IGK+++ +
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381

Query: 375 KSGPGEVKHWKDMIARPRQPVAQWHQLK 402
            S   E++HW DM+A PR+P+AQWH L+
Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQ 409


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  290 bits (742), Expect = 2e-78
 Identities = 155/388 (39%), Positives = 232/388 (59%), Gaps = 42/388 (10%)

Query: 18  LLVSAIITVSLSVTVVLCGLCHWCQRKLGKRYKNSLETVGTPDSGRGRSEKKAIKLPAGG 77
           L+  AI+ V L +T   C +C  C  K                    +  KK  K   G 
Sbjct: 61  LIAIAIVAVLLVLTCCFC-ICKKCLFK--------------------KKNKKKGKEKGGK 99

Query: 78  KAVNTAPVP--GQTPHDESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSREN 135
            A+N   V   G+T  D++ +  +  + ++D              G E++E  E    E 
Sbjct: 100 NAINMKDVKDLGKTMKDQALKDDDAETGLTD--------------GEEKEEPKE---EEK 142

Query: 136 LGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKN 195
           LG++Q+S+ Y+FQ + L V I++A ELPA D  GTSDP+VK++LLPDKK K ETKV RK 
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 202

Query: 196 LNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWK 255
           LNP +NE F F+  PY ++  + L + V D+DRFS++D IGE  +P+N VD   +   W+
Sbjct: 203 LNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWR 261

Query: 256 DLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKD 314
           DL+        + G++  SL Y P+A  + V I++A+NLK MD+GG SDPYVK+ LM   
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321

Query: 315 KRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSW 374
           KR++KKKT   K  LNP +NESF+F++P E++++  +++TV+D DK+ +ND IGK+++ +
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381

Query: 375 KSGPGEVKHWKDMIARPRQPVAQWHQLK 402
            S   E++HW DM+A PR+P+AQWH L+
Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQ 409


>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score =  268 bits (684), Expect = 8e-72
 Identities = 127/284 (44%), Positives = 193/284 (67%), Gaps = 8/284 (2%)

Query: 120 PGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYL 179
           PG +  + HE      LGR+Q+S+ Y+FQ   L V I++A  L A D  G+SDP+V++YL
Sbjct: 99  PGQQVADKHE------LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYL 152

Query: 180 LPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVS 239
           LPDK+ + ETKV R+ LNPH+ ETF F+  PY ++  R+L + V D+DRFSRND IGEV 
Sbjct: 153 LPDKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAIGEVR 211

Query: 240 IPLNKVDLTQMQTFWKDLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDI 298
           +P++ VDL +    W++L+        + G++  SL Y P+A  + V +++A+NLK MD+
Sbjct: 212 VPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDV 271

Query: 299 GGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDK 358
           GG SDPYVKV L+   K+V KKKT   K  LNP +NE+F+F++P +++++  + +TV+D 
Sbjct: 272 GGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDY 331

Query: 359 DKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLK 402
           DKL +N+ IG++ +   +G   ++HW DM+A PR+P+AQWH L+
Sbjct: 332 DKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLR 375


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  261 bits (668), Expect = 6e-70
 Identities = 131/280 (46%), Positives = 189/280 (67%), Gaps = 8/280 (2%)

Query: 124 EDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDK 183
           + EA + C     G+I FS+ Y+++  TL V+I+KA +LPAKDF G+SDP+VKIYLLPD+
Sbjct: 138 KSEATKSC-----GKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDR 192

Query: 184 KHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIP-- 241
           K KL+T+V RK LNP ++E F F   PYE++  R L+L V D+DRFSR+D IGEV +   
Sbjct: 193 KCKLQTRVHRKTLNPTFDENFHFP-VPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNL 251

Query: 242 LNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGT 301
               DL++  + WKD++  +  S   GE++ SLCY P+A  + + +IK RNLKAMDI G 
Sbjct: 252 FEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGY 311

Query: 302 SDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKL 361
           SDPYVKV L+   +R++KKKT   K  LNP++NE+  FDIP E + + +++I+VMD D++
Sbjct: 312 SDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRV 371

Query: 362 SRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQL 401
             N++IG   +   +      HW +M+A PR+P+A WH L
Sbjct: 372 GHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  251 bits (641), Expect = 8e-67
 Identities = 130/308 (42%), Positives = 196/308 (63%), Gaps = 9/308 (2%)

Query: 96  RRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVK 155
           +R E  +S+  +   L  +  + S G++ ++       +  G++ F++ Y+++   L VK
Sbjct: 198 QRGETTTSIGRIKPELYKQKSVDSEGNQNEDV------KICGKLNFTLQYDYENELLVVK 251

Query: 156 IMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVV 215
           I+KA +LPAKDF+GTSDP+VK+YLLPD+K K +T+V RK LNP ++ETF F    Y+++ 
Sbjct: 252 IIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFP-VAYDQLS 310

Query: 216 QRILYLQVLDYDRFSRNDPIGEVSIP--LNKVDLTQMQTFWKDLKPCSDGSGSRGELLLS 273
            R L+  V D+DRFSR+D IGEV +       DL++  T WKD+   +  S   GE++ S
Sbjct: 311 NRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFS 370

Query: 274 LCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIF 333
           LCY P+A  + + +IK RNLKAMDI G+SDPYVKV LM + +R++K+KT T K  LNP++
Sbjct: 371 LCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVY 430

Query: 334 NESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQ 393
           NE+  FDIP E + + ++ I VMD D++  N+VIG       +      HW +M+A  R+
Sbjct: 431 NEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRK 490

Query: 394 PVAQWHQL 401
           P+  WH L
Sbjct: 491 PITHWHPL 498


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  247 bits (631), Expect = 1e-65
 Identities = 126/267 (47%), Positives = 176/267 (65%), Gaps = 3/267 (1%)

Query: 137 GRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNL 196
           G++ F + Y+     L VKI KA  LPAKDFSGTSDP+VKIYLLPD+K K +TKV RK L
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281

Query: 197 NPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIP--LNKVDLTQMQTFW 254
           NP ++E FLF   PY  +  R L+  V D+DRFSR+D IG+V +   L+  D  +    W
Sbjct: 282 NPVFDEVFLFP-VPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILW 340

Query: 255 KDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKD 314
           KD++  ++ +   GEL+ SLCY P+A  + + IIKARNLKAMDI G SDPYVKV LM   
Sbjct: 341 KDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400

Query: 315 KRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSW 374
           +R++K+KT T +  LNP++NE+  FD+P E + +  + I VMD D++  N++IG   +  
Sbjct: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460

Query: 375 KSGPGEVKHWKDMIARPRQPVAQWHQL 401
           ++      HW +M++ PR+P+A WH L
Sbjct: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 43/104 (41%), Positives = 62/104 (59%), Gaps = 3/104 (2%)

Query: 135 NLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKH--KLETKVK 192
           +LG + FS+ Y      LT+ I+KA+ L A D +G SDP+VK+ L+ D +   K +T  K
Sbjct: 352 DLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTK 411

Query: 193 RKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIG 236
           R  LNP +NE  +F+  P E + Q  L + V+DYDR   N+ IG
Sbjct: 412 RNTLNPVYNEAIVFD-VPPENIDQIHLSIAVMDYDRVGHNEIIG 454


>gi|24308219 synaptotagmin IV [Homo sapiens]
          Length = 425

 Score =  233 bits (593), Expect = 3e-61
 Identities = 136/360 (37%), Positives = 207/360 (57%), Gaps = 14/360 (3%)

Query: 51  NSLETVGTPDSGRGRSE----KKAIKLPAGGKAVN-TAPVPGQTPHDESD-RRTEPRSSV 104
           NS +  G  D    +++    K ++ L    + +N   P     P   SD     P+  +
Sbjct: 68  NSKKKFGADDKNEVKNKPAVPKNSLHLDLEKRDLNGNFPKTNLKPGSPSDLENATPKLFL 127

Query: 105 SDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPA 164
                S++ E L  S     +E      +E LG + FS+ YNF+     V I +A+ LPA
Sbjct: 128 EGEKESVSPESLKSSTSLTSEE-----KQEKLGTLFFSLEYNFERKAFVVNIKEARGLPA 182

Query: 165 KDF-SGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQV 223
            D  S TSDP++K+ +LP+KKHK++T+V RK L+P ++ETF F G PY ++ +  L+  +
Sbjct: 183 MDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTI 242

Query: 224 LDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKD--LKPCSDGSGSRGELLLSLCYNPSAN 281
           L +DRFSR+D IGEV IPL+ ++L++ +       +K     S  RGELL+SLCY  + N
Sbjct: 243 LSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTN 302

Query: 282 SIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDI 341
           ++ V ++KAR+L   D+ G SDPYVKV L +  KR+ KKKT   K   N +FNE F FDI
Sbjct: 303 TLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDI 362

Query: 342 PTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQL 401
           P E L + ++   V+D ++ SRN+VIG++ L   +     +HWK++   PR+ +A+WH L
Sbjct: 363 PCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  231 bits (589), Expect = 9e-61
 Identities = 127/286 (44%), Positives = 175/286 (61%), Gaps = 11/286 (3%)

Query: 120 PGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYL 179
           PGS E      C     GRI F++ Y +    L V+I++A +LPAKD +G SDP+VKIYL
Sbjct: 289 PGSGEAGTGAPC-----GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYL 343

Query: 180 LPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVS 239
           LPD+K K +TKV RK LNP +NETF F   P  ++ QR L+  V D+DRFSR+D IG+V 
Sbjct: 344 LPDRKKKFQTKVHRKTLNPVFNETFQFS-VPLAELAQRKLHFSVYDFDRFSRHDLIGQVV 402

Query: 240 IPLNKVDLTQM---QTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAM 296
           +  N ++L +    +  W+D+          GEL  SLCY P+A  + V IIKA NLKAM
Sbjct: 403 LD-NLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAM 461

Query: 297 DIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVM 356
           D+ G SDPYVK  L+ + +R++K+KT   K  LNP +NE+  FD+  E +    + I V+
Sbjct: 462 DLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVV 521

Query: 357 DKDKLSRNDVIGKIYLSWKSG-PGEVKHWKDMIARPRQPVAQWHQL 401
           D D +  N+VIG   +   +  P   +HW +M+A PR+PV  WHQL
Sbjct: 522 DYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  231 bits (589), Expect = 9e-61
 Identities = 127/286 (44%), Positives = 175/286 (61%), Gaps = 11/286 (3%)

Query: 120 PGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYL 179
           PGS E      C     GRI F++ Y +    L V+I++A +LPAKD +G SDP+VKIYL
Sbjct: 289 PGSGEAGTGAPC-----GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYL 343

Query: 180 LPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVS 239
           LPD+K K +TKV RK LNP +NETF F   P  ++ QR L+  V D+DRFSR+D IG+V 
Sbjct: 344 LPDRKKKFQTKVHRKTLNPVFNETFQFS-VPLAELAQRKLHFSVYDFDRFSRHDLIGQVV 402

Query: 240 IPLNKVDLTQM---QTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAM 296
           +  N ++L +    +  W+D+          GEL  SLCY P+A  + V IIKA NLKAM
Sbjct: 403 LD-NLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAM 461

Query: 297 DIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVM 356
           D+ G SDPYVK  L+ + +R++K+KT   K  LNP +NE+  FD+  E +    + I V+
Sbjct: 462 DLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVV 521

Query: 357 DKDKLSRNDVIGKIYLSWKSG-PGEVKHWKDMIARPRQPVAQWHQL 401
           D D +  N+VIG   +   +  P   +HW +M+A PR+PV  WHQL
Sbjct: 522 DYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  231 bits (589), Expect = 9e-61
 Identities = 127/286 (44%), Positives = 175/286 (61%), Gaps = 11/286 (3%)

Query: 120 PGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYL 179
           PGS E      C     GRI F++ Y +    L V+I++A +LPAKD +G SDP+VKIYL
Sbjct: 289 PGSGEAGTGAPC-----GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYL 343

Query: 180 LPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVS 239
           LPD+K K +TKV RK LNP +NETF F   P  ++ QR L+  V D+DRFSR+D IG+V 
Sbjct: 344 LPDRKKKFQTKVHRKTLNPVFNETFQFS-VPLAELAQRKLHFSVYDFDRFSRHDLIGQVV 402

Query: 240 IPLNKVDLTQM---QTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAM 296
           +  N ++L +    +  W+D+          GEL  SLCY P+A  + V IIKA NLKAM
Sbjct: 403 LD-NLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAM 461

Query: 297 DIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVM 356
           D+ G SDPYVK  L+ + +R++K+KT   K  LNP +NE+  FD+  E +    + I V+
Sbjct: 462 DLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVV 521

Query: 357 DKDKLSRNDVIGKIYLSWKSG-PGEVKHWKDMIARPRQPVAQWHQL 401
           D D +  N+VIG   +   +  P   +HW +M+A PR+PV  WHQL
Sbjct: 522 DYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567


>gi|216548478 synaptotagmin XI [Homo sapiens]
          Length = 431

 Score =  228 bits (582), Expect = 6e-60
 Identities = 157/442 (35%), Positives = 229/442 (51%), Gaps = 75/442 (16%)

Query: 13  PSRDV------LLVSAIITVSLSVTVVLCGLCHWCQRKLGKR------------------ 48
           PS DV      L+ ++++ V +SVTV +   CH    K  K                   
Sbjct: 9   PSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLKGISIYPET 68

Query: 49  --YKNSLETVGTPDSGRGR-----------------SEKKAIKLPAGGKAVNTAPVPGQT 89
              K  +  V     G GR                 S  K  + P+ G  ++  P+    
Sbjct: 69  LSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPI---- 124

Query: 90  PHDESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQE 149
              + D   E RS ++ L      E    SP S E++         LG + FSV YNF +
Sbjct: 125 ---KMDYGEELRSPITSLT---PGESKTTSPSSPEEDV-------MLGSLTFSVDYNFPK 171

Query: 150 STLTVKIMKAQELPA-KDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEG 208
             L V I +A  LP   D +  SDP++K+ +LPDK+H+++T+V RK L+P ++ETF F G
Sbjct: 172 KALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYG 231

Query: 209 FPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPL-------NKVDLTQMQTFWKDLKPCS 261
            PY ++   +L+  VL +DRFSR+D IGEV +PL        KV LT+     ++++ C 
Sbjct: 232 IPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTR-DIIKRNIQKCI 290

Query: 262 DGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTS-DPYVKVWLMYKDKRVEKK 320
               SRGEL +SL Y P A  + V ++KAR+L  MDI G S +PYVKV + Y  KR+ KK
Sbjct: 291 ----SRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKK 346

Query: 321 KTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGE 380
           KT   K  LNPIFNESF +DIPT+ L + +I   V+D D+ ++N+V+G++ L   S    
Sbjct: 347 KTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTAS 406

Query: 381 -VKHWKDMIARPRQPVAQWHQL 401
             +HW+++   PR+PVA+WH L
Sbjct: 407 GAEHWREVCESPRKPVAKWHSL 428


>gi|40068038 B/K protein [Homo sapiens]
          Length = 474

 Score =  213 bits (543), Expect = 2e-55
 Identities = 124/324 (38%), Positives = 190/324 (58%), Gaps = 27/324 (8%)

Query: 92  DESDRRTEPR----SSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNF 147
           D+  R+ EP      S SD V+SLT E ++              S+  LG + FS  Y+ 
Sbjct: 151 DDYFRKFEPHLYSLDSNSDDVDSLTDEEIL--------------SKYQLGMLHFSTQYDL 196

Query: 148 QESTLTVKIMKAQELP-------AKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHW 200
             + LTV++++A++LP       ++     S+P+VKI LLPD+K+  +T VKRK   P +
Sbjct: 197 LHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVF 256

Query: 201 NETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPC 260
            E + FE  P+ +  +R L L V+D+D+FSR+  IG+VS+PL +VDL +   +WK L P 
Sbjct: 257 EERYTFE-IPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPS 315

Query: 261 SDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKK 320
           S      GELLLSL Y PSA  + V++I+A+ L   D+   SDP+VK+ L++  K V+ K
Sbjct: 316 SQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTK 375

Query: 321 KTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYL-SWKSGPG 379
           KT  ++  ++P +NESF+F +P E+L   +++ TV   +  S ND IG+I +  + SGP 
Sbjct: 376 KTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPS 435

Query: 380 EVKHWKDMIARPRQPVAQWHQLKA 403
           E  HW+ M+   R  V QWH L++
Sbjct: 436 ETNHWRRMLNTHRTAVEQWHSLRS 459


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score =  178 bits (451), Expect = 9e-45
 Identities = 102/309 (33%), Positives = 158/309 (51%), Gaps = 31/309 (10%)

Query: 124 EDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPD- 182
           E ++++      LG ++F + Y+    TL   I++A+ L   DF+G +DP+VK++LLP  
Sbjct: 78  EVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGA 137

Query: 183 -KKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIP 241
            K +KL+TK +R  LNP WNE   + G   + +  ++L + V D D+ S N+ IGE+ +P
Sbjct: 138 CKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVP 197

Query: 242 LNKVDLTQMQTF--------------------------WKDLKPCSDGSG---SRGELLL 272
           L ++  +Q + F                           K+L+    G G    RG +LL
Sbjct: 198 LRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILL 257

Query: 273 SLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPI 332
           SL Y+     ++V I++  +L AMD+ G SDPYVK +L     +  K KT   K+ LNP 
Sbjct: 258 SLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPE 317

Query: 333 FNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPR 392
           FNE F ++I    L   T+ +TV D D    ND IG + L   +     KHW D + +P 
Sbjct: 318 FNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPD 377

Query: 393 QPVAQWHQL 401
             + +WH L
Sbjct: 378 AALERWHTL 386


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  176 bits (445), Expect = 4e-44
 Identities = 104/292 (35%), Positives = 153/292 (52%), Gaps = 10/292 (3%)

Query: 120 PGSEED-EAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIY 178
           P  E D + +E      LG + FS+ Y+ + + L   I KA+ L   D +G +DP+VK++
Sbjct: 110 PEDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLH 169

Query: 179 LLP--DKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIG 236
           LLP   K +KL TK  R  LNP WNET  + G   E ++++ L + V D D+F  N+ IG
Sbjct: 170 LLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIG 229

Query: 237 EVSIPLNKVDLTQMQTF----WKDL---KPCSDGSGSRGELLLSLCYNPSANSIIVNIIK 289
           E  +PL K+     +TF     K L   K        RG +L+SL Y+     ++V I++
Sbjct: 230 ETRVPLKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVR 289

Query: 290 ARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRET 349
             +L AMD  G SDPYVK +L     +  K KT   K+ LNP FNE F ++I    L + 
Sbjct: 290 CAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKK 349

Query: 350 TIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQL 401
           ++ +TV D D    ND IG + L   +    +KHW D +    + + +WH L
Sbjct: 350 SLEVTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTL 401


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  172 bits (436), Expect = 5e-43
 Identities = 109/312 (34%), Positives = 160/312 (51%), Gaps = 29/312 (9%)

Query: 120 PGSEEDEAHEGCSRE--NLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKI 177
           P  EE+EA+   S E   LG ++FS+ Y+   S+L   I+KA+ L   D +G +DP+VK+
Sbjct: 375 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 434

Query: 178 YLLP--DKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPI 235
           +LLP   K +KL TK  R   NP WNET ++ G   E + ++ L + V D D+F  N+ I
Sbjct: 435 HLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFI 494

Query: 236 GEVSIPLNKVDLTQMQTFWKDLKPC-------SDGSG------------------SRGEL 270
           GE    L K+   Q + F   L+         + GS                    RG++
Sbjct: 495 GETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKI 554

Query: 271 LLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLN 330
           L+SL Y+     +IV II+  +L AMD  G SDP+VK+WL     +  K KT   K+ LN
Sbjct: 555 LVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLN 614

Query: 331 PIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIAR 390
           P FNE F +DI    L + ++ I+V D D    ND IG   L   +    +KHW + +  
Sbjct: 615 PEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKN 674

Query: 391 PRQPVAQWHQLK 402
             + + +WHQL+
Sbjct: 675 KDKKIERWHQLQ 686


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  172 bits (436), Expect = 5e-43
 Identities = 109/312 (34%), Positives = 160/312 (51%), Gaps = 29/312 (9%)

Query: 120 PGSEEDEAHEGCSRE--NLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKI 177
           P  EE+EA+   S E   LG ++FS+ Y+   S+L   I+KA+ L   D +G +DP+VK+
Sbjct: 371 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 430

Query: 178 YLLP--DKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPI 235
           +LLP   K +KL TK  R   NP WNET ++ G   E + ++ L + V D D+F  N+ I
Sbjct: 431 HLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFI 490

Query: 236 GEVSIPLNKVDLTQMQTFWKDLKPC-------SDGSG------------------SRGEL 270
           GE    L K+   Q + F   L+         + GS                    RG++
Sbjct: 491 GETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKI 550

Query: 271 LLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLN 330
           L+SL Y+     +IV II+  +L AMD  G SDP+VK+WL     +  K KT   K+ LN
Sbjct: 551 LVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLN 610

Query: 331 PIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIAR 390
           P FNE F +DI    L + ++ I+V D D    ND IG   L   +    +KHW + +  
Sbjct: 611 PEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKN 670

Query: 391 PRQPVAQWHQLK 402
             + + +WHQL+
Sbjct: 671 KDKKIERWHQLQ 682


>gi|94536846 synaptotagmin VIII [Homo sapiens]
          Length = 401

 Score =  161 bits (407), Expect = 1e-39
 Identities = 98/309 (31%), Positives = 170/309 (55%), Gaps = 12/309 (3%)

Query: 97  RTEPRSSVSDLVNSL--TSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTV 154
           R +PR   S  + S   T+   ++ P  +  E+  G +++  GR+Q S+ ++F    + V
Sbjct: 78  RKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQ-WGRLQLSLEFDFGSQEIRV 136

Query: 155 KIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKV 214
            + +A +L      GT DP+ ++ +     H+ ETKV R  L P ++ET  F   P  ++
Sbjct: 137 GLRQAADLRP---GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH-IPQAEL 192

Query: 215 VQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSR-GELLLS 273
               L +Q+ ++ RFS ++P+GE+ +PL  VDL  +   W  L P +     + GEL  S
Sbjct: 193 PGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFS 252

Query: 274 LCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIF 333
           L Y PS+  + V +++AR L+     G ++PYVKV LM   ++ +K+KT T K    P F
Sbjct: 253 LRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYF 308

Query: 334 NESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQ 393
           NE+F F +P  +++   +++ V D+    R + +GK++L  ++    ++HW DM+A  R+
Sbjct: 309 NEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARR 368

Query: 394 PVAQWHQLK 402
           P+AQ H L+
Sbjct: 369 PIAQRHPLR 377


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score =  153 bits (386), Expect = 3e-37
 Identities = 92/300 (30%), Positives = 163/300 (54%), Gaps = 12/300 (4%)

Query: 107 LVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKD 166
           +V ++  E+        E +  +GC    LGR+ FSV Y  +   L V ++KAQ L A  
Sbjct: 123 MVGAINPELYKFPEDKSETDFPDGC----LGRLWFSVEYEQEAERLLVGLIKAQHLQAP- 177

Query: 167 FSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDY 226
            S T  P VK+YLLPD++  L++K KRK  NP ++E F+F+    + + QR+L   V   
Sbjct: 178 -SETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHV 235

Query: 227 DRFSRNDPIGEVSIPLNKVDLTQ--MQTFWKDLKPCS-DGSGSRGELLLSLCYNPSANSI 283
           DR  ++  +G+V  PL    L     +  W+DL+  S +     G+L   L YN   + +
Sbjct: 236 DRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRL 295

Query: 284 IVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPT 343
            V +++A+ L+  +  G    +VKV LM  +K V+ KKT  +  ++NP++NE+F+F    
Sbjct: 296 TVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADA 355

Query: 344 EKLRETTIIITVMDKDKLSRNDVIGKIYLS--WKSGPGEVKHWKDMIARPRQPVAQWHQL 401
            +L   ++ +TV+   +  ++  +G++ +     +   E++HW +M+++P++ V +WH L
Sbjct: 356 TELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415


>gi|29366828 synaptotagmin XII [Homo sapiens]
          Length = 421

 Score =  138 bits (347), Expect = 1e-32
 Identities = 79/269 (29%), Positives = 148/269 (55%), Gaps = 4/269 (1%)

Query: 136 LGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKN 195
           LG+++ S+ Y+    TL V +M+ ++L  ++ +     F+++ LLPD++    ++++R  
Sbjct: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212

Query: 196 LNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTF-- 253
            +  ++E F     P   + ++ L   V   D   RN   G V + L+ +DL  +Q F  
Sbjct: 213 YSIFFDEKFSIPLDP-TALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLP-LQPFSG 270

Query: 254 WKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYK 313
           W  L+  +  + + GE+LLSL Y P+A  + V ++KA+NL   +   T+DP+VKV+L+  
Sbjct: 271 WLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQD 330

Query: 314 DKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLS 373
            +++ KKKT   + + NP+FNE+  F +P   L++ ++ +TV +     R D +G + + 
Sbjct: 331 GRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIG 390

Query: 374 WKSGPGEVKHWKDMIARPRQPVAQWHQLK 402
             +      HW  M+A  R+PV+ WH ++
Sbjct: 391 PSASGMGTTHWNQMLATLRRPVSMWHAVR 419


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  131 bits (330), Expect = 9e-31
 Identities = 96/300 (32%), Positives = 149/300 (49%), Gaps = 44/300 (14%)

Query: 137 GRIQFSVGYNFQESTLTVKIMKAQELP-AKDFSGTSDPFVKIYLLPDKKH--KLETKVKR 193
           GRI FS+ Y  Q  +L V + +  +L  A +    S+P+VK YLLPDK    K +T +KR
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 194 KNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTF 253
             +NP ++ET  +E  P   + QR L   V  + RF RN  +GE  I ++   L      
Sbjct: 418 DTINPLYDETLRYE-IPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLD----- 471

Query: 254 WKDLKPCSDGSGS------------RGELLLSLCYNPSANSII----------------V 285
            K L  C    G             +GEL++SL Y P++ + +                V
Sbjct: 472 -KKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQV 530

Query: 286 NIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFD-IPTE 344
            I +A+NL A   GGTSD +VK +L+    +  K+KT  MK+ LNP +N +F ++ +  E
Sbjct: 531 WIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLE 590

Query: 345 KLRETTIIITVMDKDKLSRNDVIGKIYLSWKSG--PGEVKHWKDMIARPRQPVAQWHQLK 402
            L+   + +TV D++ L+ ND +G + L   +G   GEV  W D      + V+ W +++
Sbjct: 591 DLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTG---EEVSLWQKMR 647


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  131 bits (330), Expect = 9e-31
 Identities = 96/300 (32%), Positives = 149/300 (49%), Gaps = 44/300 (14%)

Query: 137 GRIQFSVGYNFQESTLTVKIMKAQELP-AKDFSGTSDPFVKIYLLPDKKH--KLETKVKR 193
           GRI FS+ Y  Q  +L V + +  +L  A +    S+P+VK YLLPDK    K +T +KR
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 194 KNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTF 253
             +NP ++ET  +E  P   + QR L   V  + RF RN  +GE  I ++   L      
Sbjct: 418 DTINPLYDETLRYE-IPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLD----- 471

Query: 254 WKDLKPCSDGSGS------------RGELLLSLCYNPSANSII----------------V 285
            K L  C    G             +GEL++SL Y P++ + +                V
Sbjct: 472 -KKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQV 530

Query: 286 NIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFD-IPTE 344
            I +A+NL A   GGTSD +VK +L+    +  K+KT  MK+ LNP +N +F ++ +  E
Sbjct: 531 WIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLE 590

Query: 345 KLRETTIIITVMDKDKLSRNDVIGKIYLSWKSG--PGEVKHWKDMIARPRQPVAQWHQLK 402
            L+   + +TV D++ L+ ND +G + L   +G   GEV  W D      + V+ W +++
Sbjct: 591 DLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTG---EEVSLWQKMR 647


>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
          Length = 390

 Score =  131 bits (329), Expect = 1e-30
 Identities = 85/260 (32%), Positives = 139/260 (53%), Gaps = 13/260 (5%)

Query: 107 LVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKD 166
           +V ++  E+        E +  +GC    LGR+ FSV Y  +   L V ++KAQ L A  
Sbjct: 123 MVGAINPELYKFPEDKSETDFPDGC----LGRLWFSVEYEQEAERLLVGLIKAQHLQAP- 177

Query: 167 FSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDY 226
            S T  P VK+YLLPD++  L++K KRK  NP ++E F+F+    + + QR+L   V   
Sbjct: 178 -SETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHV 235

Query: 227 DRFSRNDPIGEVSIPLNKVDLTQ--MQTFWKDLKPCS-DGSGSRGELLLSLCYNPSANSI 283
           DR  ++  +G+V  PL    L     +  W+DL+  S +     G+L   L YN   + +
Sbjct: 236 DRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRL 295

Query: 284 IVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPT 343
            V +++A+ L+  +  G    +VKV LM  +K V+ KKT  +  ++NP++NE+F+F    
Sbjct: 296 TVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADA 355

Query: 344 EKLRETTIIITV---MDKDK 360
            +L   ++ +TV   M+ DK
Sbjct: 356 TELDTASLSLTVVQNMEGDK 375



 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 38/158 (24%), Positives = 81/158 (51%), Gaps = 8/158 (5%)

Query: 249 QMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKV 308
           ++  F +D        G  G L  S+ Y   A  ++V +IKA++L+A     T  P VK+
Sbjct: 130 ELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPS--ETCSPLVKL 187

Query: 309 WLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIG 368
           +L+  ++R  + KT   ++  NP F+E F F + ++ + +  +  +V   D+  ++ ++G
Sbjct: 188 YLLPDERRFLQSKT--KRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLG 245

Query: 369 KIYLSWKSGP--GEVKH--WKDMIARPRQPVAQWHQLK 402
           ++    K+    G+ +   W+D+ A   +P +++  L+
Sbjct: 246 QVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQ 283


>gi|24308233 synaptotagmin XIII [Homo sapiens]
          Length = 426

 Score =  124 bits (311), Expect = 2e-28
 Identities = 86/325 (26%), Positives = 165/325 (50%), Gaps = 14/325 (4%)

Query: 82  TAPVPGQTPHDESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQF 141
           TAP   Q P+D   +R           N +  ++ ++   + E  A    S     ++ +
Sbjct: 109 TAPASPQPPNDSRLKRQVTEELFILPQNGVVEDVCVMETWNPEKAA----SWNQAPKLHY 164

Query: 142 SVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKH-KLETKVKRKNLNPHW 200
            + Y+ Q++ L V  ++A      +  G  D +V+  +       + +T +K++ L+  W
Sbjct: 165 CLDYDCQKAELFVTRLEAV---TSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTW 221

Query: 201 NETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPC 260
            E  +      E++    L L +   DRFSR+   GE+ + L+   +      W +LK  
Sbjct: 222 EEGLVLP-LAEEELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGELKTS 280

Query: 261 S-DGSGSRGELLLSLCYNPSANSIIVNIIKARNL---KAMDIGGTSDPYVKVWLMYKDKR 316
           + + S   GE+LLS+ Y P+AN ++V +IKA+NL   ++ ++ G  D  VKV L ++ ++
Sbjct: 281 AKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLG-KDVSVKVTLKHQARK 339

Query: 317 VEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKS 376
           ++KK+T   K  +NP++NE   F++P + L+ +++ + V+ +D   ++  +G   L   +
Sbjct: 340 LKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHT 399

Query: 377 GPGEVKHWKDMIARPRQPVAQWHQL 401
              E  HW++M+  PR+ +A WHQL
Sbjct: 400 SGSERSHWEEMLKNPRRQIAMWHQL 424


>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
           sapiens]
          Length = 431

 Score =  115 bits (287), Expect = 9e-26
 Identities = 82/304 (26%), Positives = 141/304 (46%), Gaps = 22/304 (7%)

Query: 119 SPGSEEDEAHEGCSREN--LGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVK 176
           +P  + D   EG S ++  LG ++F++ +    S L     +A+ L     SG++D +VK
Sbjct: 120 APQLQPDPEPEGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPLA-SGSADAYVK 178

Query: 177 IYLLP--DKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDP 234
             LLP   K  +L T   R    P W ET  + GF  +    + L   +  +       P
Sbjct: 179 ANLLPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGP 238

Query: 235 ----------IGEVSIPLNKVDLTQMQTFWKDLKP-------CSDGSGSRGELLLSLCYN 277
                     +GE+ +PL K+   + ++F   L+                G +LLSLCY+
Sbjct: 239 MVQRQWQAPSLGELRVPLRKLVPNRARSFDICLEKRRLEEVETEVAWEECGHVLLSLCYS 298

Query: 278 PSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESF 337
                ++V +++  +L  MD  G SDP+V+++L     +  K KT   ++ LNP FNE F
Sbjct: 299 SQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEF 358

Query: 338 AFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQ 397
            +  P E+L + T++++V D D  + +D IG + L   +    ++HW + +      +  
Sbjct: 359 FYSGPREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHWLECLGHSDHRLKL 418

Query: 398 WHQL 401
           WH L
Sbjct: 419 WHPL 422


>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
          Length = 550

 Score =  115 bits (287), Expect = 9e-26
 Identities = 99/328 (30%), Positives = 156/328 (47%), Gaps = 28/328 (8%)

Query: 81  NTAPVPGQTPHDESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQ 140
           N    PG  P    DR     SSVS L +S  S   M   G  E       + +  G + 
Sbjct: 209 NGEEAPGPDP--SLDRMLSSSSSVSSLNSSTLSGSQMSLSGDAE-------AVQVRGSVH 259

Query: 141 FSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHW 200
           F++ Y    + L V +++ Q L A      SDP+VK YLLPDK+ K +T VK++NLNP +
Sbjct: 260 FALHYEPGAAELRVHVIQCQGLAAAR-RRRSDPYVKSYLLPDKQSKRKTAVKKRNLNPVF 318

Query: 201 NETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLK-- 258
           NET  +   P  ++  R+L L V   +   RN  +GEV +PL+  D     T W  L+  
Sbjct: 319 NETLRY-SVPQAELQGRVLSLSVWHRESLGRNIFLGEVEVPLDTWDWGSEPT-WLPLQPR 376

Query: 259 --PCSDGSGSRGELLLSLCYNPS---------ANSIIVNIIKARNLKAMDIGGTSDPYVK 307
             P  D   SRG L LSL Y P+         +  +   + +AR+L  +   G+ D YV+
Sbjct: 377 VPPSPDDLPSRGLLALSLKYVPAGSEGAGLPPSGELHFWVKEARDLLPLR-AGSLDTYVQ 435

Query: 308 VWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFD-IPTEKLRETTIIITVMDKDKLSRNDV 366
            +++  D +  +++T  ++R+L+P+FN +  +D      LR+    +++ D   L+   +
Sbjct: 436 CFVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGALANRQL 495

Query: 367 IG-KIYLSWKSGPGEVKHWKDMIARPRQ 393
            G ++ L   S  G    W D     +Q
Sbjct: 496 GGTRLSLGTGSSYGLQVPWMDSTPEEKQ 523


>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
          Length = 600

 Score =  104 bits (259), Expect = 2e-22
 Identities = 87/351 (24%), Positives = 149/351 (42%), Gaps = 31/351 (8%)

Query: 81  NTAPVPGQTPHD-ESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEED--EAHEGCSRENLG 137
           N  P  G T H+ ES         V     ++ S   M + GS     +  +       G
Sbjct: 248 NKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYG 307

Query: 138 RIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLN 197
            +  +  Y+ QE  L V +    ++P  + +G +   V + LLP KK + +T ++R    
Sbjct: 308 TLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC- 366

Query: 198 PHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDL 257
           P + ETF F     E +    +  ++    R  +   +GE    L K++L    +    L
Sbjct: 367 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 426

Query: 258 KP-----------------CSDGS--------GSRGELLLSLCYNPSANSIIVNIIKARN 292
           +P                 CS+ +        GS  E+L+ L YN +   +   +IK  +
Sbjct: 427 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 486

Query: 293 LKAMDIGGTSDPYVKVWLMYK-DKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTI 351
            K +      + YVK+ L+    + + K KT   +   NP++ E+F F +   +L + T+
Sbjct: 487 FKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTL 546

Query: 352 IITVMDKDKLSRNDVIGKIYLSW-KSGPGEVKHWKDMIARPRQPVAQWHQL 401
           I++V +K  + R ++IG I L    SG  E+ HW +M     Q V +WH L
Sbjct: 547 ILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,391,368
Number of Sequences: 37866
Number of extensions: 744228
Number of successful extensions: 3058
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 2057
Number of HSP's gapped (non-prelim): 573
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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