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Search of human proteins with 38372911
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
(665 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 1321 0.0
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 495 e-140
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 180 4e-45
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 173 4e-43
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 163 4e-40
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 161 2e-39
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 159 8e-39
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 156 7e-38
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 147 4e-35
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 131 2e-30
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 125 2e-28
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 107 4e-23
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 107 4e-23
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 103 5e-22
gi|239582767 slingshot homolog 3 [Homo sapiens] 96 1e-19
gi|37674210 slingshot 2 [Homo sapiens] 91 3e-18
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 90 6e-18
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 90 6e-18
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 90 6e-18
gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens] 87 4e-17
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 87 5e-17
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 85 2e-16
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 83 7e-16
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 81 3e-15
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 81 3e-15
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 81 3e-15
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 81 3e-15
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 80 6e-15
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 80 8e-15
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 75 2e-13
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 1321 bits (3418), Expect = 0.0
Identities = 665/665 (100%), Positives = 665/665 (100%)
Query: 1 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ 60
MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ
Sbjct: 1 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ 60
Query: 61 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL 120
DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL
Sbjct: 61 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL 120
Query: 121 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM 180
LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM
Sbjct: 121 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM 180
Query: 181 QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV 240
QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV
Sbjct: 181 QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV 240
Query: 241 LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN 300
LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN
Sbjct: 241 LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN 300
Query: 301 QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV 360
QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV
Sbjct: 301 QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV 360
Query: 361 PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF 420
PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF
Sbjct: 361 PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF 420
Query: 421 SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ 480
SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ
Sbjct: 421 SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ 480
Query: 481 SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH 540
SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH
Sbjct: 481 SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH 540
Query: 541 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR 600
SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR
Sbjct: 541 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR 600
Query: 601 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME 660
QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME
Sbjct: 601 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME 660
Query: 661 IIEVS 665
IIEVS
Sbjct: 661 IIEVS 665
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 495 bits (1275), Expect = e-140
Identities = 305/665 (45%), Positives = 389/665 (58%), Gaps = 65/665 (9%)
Query: 13 ERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHS 72
++L +LL G L+IDSR FVEYN+ H+L ++NI CSKL+KRRLQQ KV I ELIQ +
Sbjct: 14 KKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPA 73
Query: 73 AKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCF 132
A+ +V+ Q VVVYDQS++D + L++D FL++LL KL+ F+SV +L GGFA FS CF
Sbjct: 74 ARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCF 133
Query: 133 PGLCEGK-STLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNA 191
PGLCEGK + L+P +SQPCLPV ++G TRILP+LYLG Q+DVLNK+LM QNGI YVLNA
Sbjct: 134 PGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNA 193
Query: 192 SNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRS 251
SN+CPKPDFI ES F+RVP+ND++CEK+LPWLDKS++FI+KAK S+ V+VHCLAGISRS
Sbjct: 194 SNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRS 253
Query: 252 ATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKSKL 311
ATIAIAYIMK M MS D+AYRFVK++RP+ISPNFNFLGQLL+YE+ +K G
Sbjct: 254 ATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQGDPGT- 312
Query: 312 KLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSLL 371
EP P+ + G P PP ++SA + A R S P P+
Sbjct: 313 ----PSGTPEPPPSPAAGAPLPRLP--PPTSESAATGNAAARE-GGLSAGGEPPAPPTPP 365
Query: 372 EDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYK 431
S L Q L GLHLS+DRL+D+N+LKRSFSLDIKS Y
Sbjct: 366 ATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSA----------------------YA 403
Query: 432 PSTTLDGTN--------KLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQSKR 483
PS DG KLC+ + SPD +A+ ARP + R
Sbjct: 404 PSRRPDGPGPPDPGEAPKLCKLDSPSGAALGLSSPSPDSPDAA-----PEARPRPRRRPR 458
Query: 484 LHSVRTSSSGTAQRSLLSPLHRSG-SVEDNYHTSFLFGLSTSQQHLTKSAG--LGLKGWH 540
+G+ R SP H G + D + GLS G G W
Sbjct: 459 ------PPAGSPAR---SPAHSLGLNFGDAARQTPRHGLSALSAPGLPGPGQPAGPGAWA 509
Query: 541 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR 600
+ +P TPS W F+ E A G ++ + + P G RR
Sbjct: 510 PPLDSP--GTPSPDGPWCFSPE-------GAQGAGGVLFAPFGRAGAPGPGGGSDLRRRE 560
Query: 601 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME 660
++ D+R W EE E QFKRRSCQMEF E ++ EEL +G Q+SFSGS+E
Sbjct: 561 AARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEGMVEGRARGEELAALGKQASFSGSVE 620
Query: 661 IIEVS 665
+IEVS
Sbjct: 621 VIEVS 625
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 180 bits (456), Expect = 4e-45
Identities = 106/294 (36%), Positives = 171/294 (58%), Gaps = 22/294 (7%)
Query: 27 LLIDSRPFVEYNTSHILEAININCS-KLMKRRLQQDKVLITELIQ-HSAKHKVDIDCSQK 84
++ID RPF+EYN SHI A++INC+ K+ +RRLQQ K+ + +LI K S++
Sbjct: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKE 232
Query: 85 VVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGK----- 139
++VYD+++ + + + L ++L L++ +L GG + F + LC+
Sbjct: 233 IIVYDENTNEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQE 292
Query: 140 -----------STLVPTCISQPCLP-VANIGPTRILPNLYLGCQRDVLNKELMQQNGIGY 187
S+L+P I P P + N T ILP L+LG ++D + + MQ+ IGY
Sbjct: 293 CREVGGGASAASSLLPQPI--PTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGY 350
Query: 188 VLNASNTCPKPDFIPES-HFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLA 246
V+N + P + ++ R+P DS + + + +++ +FIE+A +L+HC A
Sbjct: 351 VINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQA 410
Query: 247 GISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN 300
G+SRSATI IAY+MK M++ +AY+FVK KRP ISPN NF+GQLL++E+ + N
Sbjct: 411 GVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNN 464
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 173 bits (439), Expect = 4e-43
Identities = 113/332 (34%), Positives = 176/332 (53%), Gaps = 49/332 (14%)
Query: 19 LESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSA-KHKV 77
LE G E++LL+D RP Y +SHI AIN+ +M RRLQ+ + + L + +
Sbjct: 27 LELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRF 86
Query: 78 DIDC-SQKVVVYDQSSQDV-ASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGL 135
C + VV+YD+SS D + + L +LL KL+ L GGF++F F
Sbjct: 87 TRRCGTDTVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLH 146
Query: 136 CEGKSTLVPTCISQ-PCLPVANIG------------------------------------ 158
CE + L +C S P LPV +G
Sbjct: 147 CE--TNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQP 204
Query: 159 --PTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKP-DFIPESHFLRVPVNDSF 215
P ILP LYLGC +D N +++++ GI Y+LN + P + E + ++P++D +
Sbjct: 205 SFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHW 264
Query: 216 CEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVK 275
+ + + +++ FI++A+ N VLVHCLAGISRS T+ +AY+M+++++S+++AY VK
Sbjct: 265 SQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVK 324
Query: 276 EKRPTISPNFNFLGQLLDYEKKIKNQTGASGP 307
K+ ISPNFNF+GQLLD+E+ + G S P
Sbjct: 325 MKKSNISPNFNFMGQLLDFERTL----GLSSP 352
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 163 bits (413), Expect = 4e-40
Identities = 113/365 (30%), Positives = 187/365 (51%), Gaps = 43/365 (11%)
Query: 25 KVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELI--QHSAKHKVDIDCS 82
K LL+D RPF+ ++ +IL ++N+ C+ +++RR + V + +++ + + ++
Sbjct: 44 KCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAK-GSVSLEQILPAEEEVRARLRSGLY 102
Query: 83 QKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFN--SVHLLAGGFAEFSRCFPGLCEGKS 140
V+VYD+ S SL D +++++ L ++ + LL GG+ FS +P C
Sbjct: 103 SAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTK 162
Query: 141 TL------VPTCISQPC--------LPVANIG-PTRILPNLYLGCQRDVLNKELMQQNGI 185
L VP ++P P+ + G P ILP LYLG ++++ GI
Sbjct: 163 ALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGI 222
Query: 186 GYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCL 245
+LN S+ CP F + +PV D+ I W +++++I+ K G VLVHC
Sbjct: 223 TALLNVSSDCPN-HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQ 281
Query: 246 AGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGAS 305
AGISRSATI +AY+M + + L+EA+ FVK++R ISPNF+F+GQLL +E ++ + A+
Sbjct: 282 AGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAA 341
Query: 306 GPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPS 365
S P+ P+ ++ +TP +P TS+ PV V S PS
Sbjct: 342 EAAS---------PSGPL------RERGKTPATP------TSQFVFSFPV-SVGVHSAPS 379
Query: 366 VQPSL 370
P L
Sbjct: 380 SLPYL 384
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 161 bits (408), Expect = 2e-39
Identities = 105/327 (32%), Positives = 169/327 (51%), Gaps = 45/327 (13%)
Query: 22 GTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELI-QHSAKHKVDID 80
G +LL+D RP + +SHI AIN+ LM RRL++ + I +I H+ K +
Sbjct: 68 GGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATR 127
Query: 81 C-SQKVVVYDQSSQDVASL--SSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCE 137
C + V++YD+++ + + L +LL KL + L GGF +F + CE
Sbjct: 128 CKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCE 187
Query: 138 GKSTLVPTCISQPCLPVANIG------------------------------------PTR 161
+ S P V +G P +
Sbjct: 188 TNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQ 247
Query: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKP-DFIPESHFLRVPVNDSFCEKIL 220
ILP LYLGC +D N +++ + GI Y+LN + P + E + ++P++D + + +
Sbjct: 248 ILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLS 307
Query: 221 PWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPT 280
+ +++ FI++A++ VLVHCLAGISRS T+ +AY+M++M++SL++AY FVK K+
Sbjct: 308 QFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSN 367
Query: 281 ISPNFNFLGQLLDYEKKIKNQTGASGP 307
ISPNFNF+GQLLD+E+ + G S P
Sbjct: 368 ISPNFNFMGQLLDFERTL----GLSSP 390
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 159 bits (402), Expect = 8e-39
Identities = 102/301 (33%), Positives = 149/301 (49%), Gaps = 18/301 (5%)
Query: 15 LVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAK 74
L ALL + LL+D R F +N HI ++N+ S +++RR + L + +
Sbjct: 13 LRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELR 72
Query: 75 HKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKL--EKSFNSVHLLAGGFAEFSRCF 132
++ VV+ D+ S + D L + G L E V L GG+ FS
Sbjct: 73 GRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASC 132
Query: 133 PGLCEGKST----------LVPTCISQPCLPVANI-----GPTRILPNLYLGCQRDVLNK 177
P LC +ST VP C + GP ILP LYLG K
Sbjct: 133 PELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRK 192
Query: 178 ELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASN 237
+++ GI ++N S CP F + +PV D+ I W ++++DFI+ K +
Sbjct: 193 DMLDALGITALINVSANCPN-HFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAG 251
Query: 238 GCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKK 297
G V VHC AGISRSATI +AY+M+ + LDEA+ FVK++R ISPNF+F+GQLL +E +
Sbjct: 252 GRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQ 311
Query: 298 I 298
+
Sbjct: 312 V 312
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 156 bits (394), Expect = 7e-38
Identities = 108/297 (36%), Positives = 153/297 (51%), Gaps = 32/297 (10%)
Query: 24 EKVLLIDSRPFVEYNTSHILEAININCSKLMKRR-----------LQQDKVLITELIQHS 72
E+ LL+D RPF+ + H+ A + + L++RR L D+ L T L++
Sbjct: 25 ERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLACLLPDRALRTRLVRGE 84
Query: 73 AKHKVDIDCSQKVVVYDQSSQDVASLSSDC----FLTVLLGKLEKSFNSVHLLAGGFAEF 128
+ VV D+ S VA L D L LL + +V+ L GGF F
Sbjct: 85 LA---------RAVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGF 135
Query: 129 SRCFPGLC-EGKSTLVP-----TCISQPCLPVANIG-PTRILPNLYLGCQRDVLNKELMQ 181
C P LC E + +P T S PV + G P ILP L+LG + + +Q
Sbjct: 136 QGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQ 195
Query: 182 QNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVL 241
GI VLN S +CP F + +PV D+ +I W +++ FI+ K S G VL
Sbjct: 196 ACGITAVLNVSASCPN-HFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVL 254
Query: 242 VHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKI 298
VHC AGISRSATI +AY+M+ + LDEA+ FVK++R ISPNF+F+GQLL +E ++
Sbjct: 255 VHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQV 311
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 147 bits (370), Expect = 4e-35
Identities = 97/330 (29%), Positives = 165/330 (50%), Gaps = 60/330 (18%)
Query: 25 KVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQK 84
++LL+D R Y ++ I A+++ L+ RRL++ + + L+
Sbjct: 21 RLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPPLQPPP---PAP 77
Query: 85 VVVYDQ---------SSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGL 135
V++YDQ + + ++ L LL KL + + L GGF+ F P L
Sbjct: 78 VLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHL 137
Query: 136 CEGK------STLVPT------------CISQPCLPVAN--------------------I 157
CE S++ P C+ C + +
Sbjct: 138 CETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPV 197
Query: 158 G-----PTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPES---HFLRV 209
G P +ILPNLYLG RD N E + + GI Y+LN + P +F ++ H+ ++
Sbjct: 198 GLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLP--NFFEKNGDFHYKQI 255
Query: 210 PVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDE 269
P++D + + + + ++++FI++A + N VLVHCLAG+SRS T+ +AY+M+++ +SL++
Sbjct: 256 PISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLND 315
Query: 270 AYRFVKEKRPTISPNFNFLGQLLDYEKKIK 299
AY VK K+ ISPNFNF+GQLLD+E+ ++
Sbjct: 316 AYDLVKRKKSNISPNFNFMGQLLDFERSLR 345
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 131 bits (330), Expect = 2e-30
Identities = 96/315 (30%), Positives = 145/315 (46%), Gaps = 24/315 (7%)
Query: 18 LLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKV 77
L + + +++D RP++ + S++ ++N+N + ++ RR + V ++ A
Sbjct: 15 LRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLPDEAARAR 74
Query: 78 DIDCS----QKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNS---VHLLAGGFAEFSR 130
+ VVV DQ S+ L + V+L L + V+ L GG+ F
Sbjct: 75 LLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYS 134
Query: 131 CFPGLC-------EGKSTLVPTCISQPCLPVANI---------GPTRILPNLYLGCQRDV 174
+P C + K ISQ PV N+ GP ILP LYLG
Sbjct: 135 EYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHA 194
Query: 175 LNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAK 234
E + I +LN S + H+ +PV DS I +++DFI+ +
Sbjct: 195 SKCEFLANLHITALLNVSRRTSEA-CATHLHYKWIPVEDSHTADISSHFQEAIDFIDCVR 253
Query: 235 ASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDY 294
G VLVHC AGISRS TI +AY+MK L EA+ ++K++R +SPNF F+GQLL Y
Sbjct: 254 EKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQY 313
Query: 295 EKKIKNQTGASGPKS 309
E +I T P S
Sbjct: 314 ESEILPSTPNPQPPS 328
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 125 bits (313), Expect = 2e-28
Identities = 88/263 (33%), Positives = 131/263 (49%), Gaps = 38/263 (14%)
Query: 123 GGFAEFSRCFPGLCEGKSTL------VPTCISQPC--------LPVANIG-PTRILPNLY 167
GG+ FS +P C L VP ++P P+ + G P ILP LY
Sbjct: 54 GGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLY 113
Query: 168 LGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSV 227
LG ++++ GI +LN S+ CP F + +PV D+ I W +++
Sbjct: 114 LGSAYHAARRDMLDALGITALLNVSSDCPN-HFEGHYQYKCIPVEDNHKADISSWFMEAI 172
Query: 228 DFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNF 287
++I+ K G VLVHC AGISRSATI +AY+M + + L+EA+ FVK++R ISPNF+F
Sbjct: 173 EYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSF 232
Query: 288 LGQLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATS 347
+GQLL +E ++ + A+ S P+ P+ ++ +TP +P TS
Sbjct: 233 MGQLLQFESQVLATSCAAEAAS---------PSGPL------RERGKTPATP------TS 271
Query: 348 EAAGQRPVHPASVPSVPSVQPSL 370
+ PV V S PS P L
Sbjct: 272 QFVFSFPV-SVGVHSAPSSLPYL 293
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 107 bits (267), Expect = 4e-23
Identities = 53/122 (43%), Positives = 81/122 (66%), Gaps = 1/122 (0%)
Query: 180 MQQNGIGYVLNASNTCPKPDFIPES-HFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNG 238
MQ+ IGYV+N + P + ++ R+P DS + + + +++ +FIE+A
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 239 CVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKI 298
+L+HC AG+SRSATI IAY+MK M++ +AY+FVK KRP ISPN NF+GQLL++E+ +
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
Query: 299 KN 300
N
Sbjct: 121 NN 122
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 107 bits (267), Expect = 4e-23
Identities = 53/122 (43%), Positives = 81/122 (66%), Gaps = 1/122 (0%)
Query: 180 MQQNGIGYVLNASNTCPKPDFIPES-HFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNG 238
MQ+ IGYV+N + P + ++ R+P DS + + + +++ +FIE+A
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 239 CVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKI 298
+L+HC AG+SRSATI IAY+MK M++ +AY+FVK KRP ISPN NF+GQLL++E+ +
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
Query: 299 KN 300
N
Sbjct: 121 NN 122
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 103 bits (257), Expect = 5e-22
Identities = 61/162 (37%), Positives = 93/162 (57%), Gaps = 2/162 (1%)
Query: 138 GKSTLVPTCISQPCLPVANIGP-TRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCP 196
G STL T ++ + +IG +I +L+LG N+ L+Q GI ++NA+ P
Sbjct: 5 GHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIP 64
Query: 197 KPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAI 256
++ P+ +++VP+ D I + D D I +G LVHC AG+SRSAT+ I
Sbjct: 65 NFNW-PQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCI 123
Query: 257 AYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKI 298
AY+MK ++ L EAY +VK +RP I PN F QL+DYE+++
Sbjct: 124 AYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQL 165
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 95.5 bits (236), Expect = 1e-19
Identities = 68/205 (33%), Positives = 104/205 (50%), Gaps = 14/205 (6%)
Query: 160 TRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESH-FLRVPVNDSFCEK 218
+RI P+LYLG + + N E +Q+N + ++LN + +F PE + V + D +
Sbjct: 330 SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREID--NFYPERFTYHNVRLWDEESAQ 387
Query: 219 ILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKR 278
+LP ++ FIE A+A VLVHC G+SRSA +AY MK+ + SL++A R V+E R
Sbjct: 388 LLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELR 447
Query: 279 PTISPNFNFLGQLLDYEKKI---------KNQTGASGPKSKLKLLHLEKPNEPVPAVSEG 329
P PN FL QL Y+ + + + G P+ + P P+P EG
Sbjct: 448 PIARPNPGFLRQLQIYQGILTASRQSHVWEQKVGGVSPEEH-PAPEVSTPFPPLPPEPEG 506
Query: 330 GQKSETPLSPPCADSATSEAAGQRP 354
G + E + + +A E G RP
Sbjct: 507 GGE-EKVVGMEESQAAPKEEPGPRP 530
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 91.3 bits (225), Expect = 3e-18
Identities = 94/350 (26%), Positives = 146/350 (41%), Gaps = 52/350 (14%)
Query: 159 PTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIP---ESHFLRVPVNDSF 215
PT+I +++LG + + N E +Q G+ Y+LN + +F P E H +RV D
Sbjct: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREID--NFFPGVFEYHNIRV--YDEE 363
Query: 216 CEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVK 275
+L + + + FI KAK LVHC G+SRSA+ IAY MK +LD AY +VK
Sbjct: 364 ATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVK 423
Query: 276 EKRPTISPNFNFLGQLLDYE------KKIKNQTGASGPKSKLKLLHLEKPNEPV--PAVS 327
E+R PN +F+ QL +Y+ K+ N+ S S L H EP+ P +
Sbjct: 424 ERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHH-----EPICKPGL- 477
Query: 328 EGGQKSETPLSPPCADSATSEAAGQRPVHPA----SVPSVPSVQPSLLEDSPLVQALSGL 383
E +K T + A+ T E+ P+ P VP + + ++ + +
Sbjct: 478 ELNKKDITTSADQIAEVKTMES--HPPIPPVFVEHMVPQDANQKGLCTKERMICLEFTSR 535
Query: 384 HLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYKPSTTLDGTNKLC 443
A ++ED L DI S + S + + +P + NK
Sbjct: 536 EFHAGQIEDELNLN-----DINGCSSGCCLNESKFPLDNCHASKALIQPGHVPEMANKFP 590
Query: 444 QFS------------------PVQELSE--QTPETSPDKEEASIPKKLQT 473
+ P++EL+ + P SPD E S QT
Sbjct: 591 DLTVEDLETDALKADMNVHLLPMEELTSPLKDPPMSPDPESPSPQPSCQT 640
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 90.1 bits (222), Expect = 6e-18
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 23/204 (11%)
Query: 159 PTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESH-FLRVPVNDSFCE 217
P+ I +LYLG + + N E +Q +G+ Y+LN + +F P + + V D
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREID--NFFPGLFAYHNIRVYDEETT 366
Query: 218 KILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEK 277
+L +++ FI KAK ++ LVHC G+SRSA+ IAY MK L++AY +VK+K
Sbjct: 367 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 426
Query: 278 RPTISPNFNFLGQLLDYE-----------KKIKNQTGAS---------GPKSKLKLLHLE 317
R PN F+ QL +YE K + QT +S GP L
Sbjct: 427 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDG 486
Query: 318 KPNEPVPAVSEGGQKSETPLSPPC 341
P +P + + Q P P C
Sbjct: 487 TPESQLPFLDDAAQPGLGPPLPCC 510
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 90.1 bits (222), Expect = 6e-18
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 23/204 (11%)
Query: 159 PTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESH-FLRVPVNDSFCE 217
P+ I +LYLG + + N E +Q +G+ Y+LN + +F P + + V D
Sbjct: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREID--NFFPGLFAYHNIRVYDEETT 377
Query: 218 KILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEK 277
+L +++ FI KAK ++ LVHC G+SRSA+ IAY MK L++AY +VK+K
Sbjct: 378 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 437
Query: 278 RPTISPNFNFLGQLLDYE-----------KKIKNQTGAS---------GPKSKLKLLHLE 317
R PN F+ QL +YE K + QT +S GP L
Sbjct: 438 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDG 497
Query: 318 KPNEPVPAVSEGGQKSETPLSPPC 341
P +P + + Q P P C
Sbjct: 498 TPESQLPFLDDAAQPGLGPPLPCC 521
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 90.1 bits (222), Expect = 6e-18
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 23/204 (11%)
Query: 159 PTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESH-FLRVPVNDSFCE 217
P+ I +LYLG + + N E +Q +G+ Y+LN + +F P + + V D
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREID--NFFPGLFAYHNIRVYDEETT 366
Query: 218 KILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEK 277
+L +++ FI KAK ++ LVHC G+SRSA+ IAY MK L++AY +VK+K
Sbjct: 367 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 426
Query: 278 RPTISPNFNFLGQLLDYE-----------KKIKNQTGAS---------GPKSKLKLLHLE 317
R PN F+ QL +YE K + QT +S GP L
Sbjct: 427 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDG 486
Query: 318 KPNEPVPAVSEGGQKSETPLSPPC 341
P +P + + Q P P C
Sbjct: 487 TPESQLPFLDDAAQPGLGPPLPCC 510
>gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens]
Length = 235
Score = 87.4 bits (215), Expect = 4e-17
Identities = 40/77 (51%), Positives = 59/77 (76%), Gaps = 4/77 (5%)
Query: 231 EKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQ 290
++A+ N VLVHCLAGISRS T+ +AY+M+++++S+++AY VK K+ ISPNFNF+GQ
Sbjct: 134 DEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQ 193
Query: 291 LLDYEKKIKNQTGASGP 307
LLD+E+ + G S P
Sbjct: 194 LLDFERTL----GLSSP 206
Score = 50.1 bits (118), Expect = 7e-06
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
Query: 19 LESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSA-KHKV 77
LE G E++LL+D RP Y +SHI AIN+ +M RRLQ+ + + L + +
Sbjct: 27 LELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRF 86
Query: 78 DIDC-SQKVVVYDQSSQD-VASLSSDCFLTVLLGKLE 112
C + VV+YD+SS D + + L +LL KL+
Sbjct: 87 TRRCGTDTVVLYDESSSDWNENTGGESVLGLLLKKLK 123
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 87.0 bits (214), Expect = 5e-17
Identities = 54/153 (35%), Positives = 79/153 (51%), Gaps = 1/153 (0%)
Query: 161 RILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKIL 220
R+ P+L+LG R +E + + G+ +N S P P P LRVPV D E +L
Sbjct: 21 RVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR-APGVAELRVPVFDDPAEDLL 79
Query: 221 PWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPT 280
L+ + +E A + G LV+C G SRSA + AY+M+ +SL +A++ VK RP
Sbjct: 80 AHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPV 139
Query: 281 ISPNFNFLGQLLDYEKKIKNQTGASGPKSKLKL 313
PN F QL YE+ ++ Q+ G L L
Sbjct: 140 AEPNPGFWSQLQKYEEALQAQSCLQGEPPALGL 172
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 85.1 bits (209), Expect = 2e-16
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 1/141 (0%)
Query: 160 TRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKI 219
++I +L+L +K L+ N I ++NAS F +++VPV D+ ++
Sbjct: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNV-FFEGIQYIKVPVTDARDSRL 81
Query: 220 LPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRP 279
+ D D I G L+HC+AG+SRSA++ +AY+MK MSL +A+ + K +RP
Sbjct: 82 YDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRP 141
Query: 280 TISPNFNFLGQLLDYEKKIKN 300
I PN F QL++YE K+ N
Sbjct: 142 IIRPNNGFWEQLINYEFKLFN 162
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 83.2 bits (204), Expect = 7e-16
Identities = 46/139 (33%), Positives = 76/139 (54%), Gaps = 2/139 (1%)
Query: 158 GPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCE 217
G +ILP LY+G +D + E + +N + ++L+ ++ +P + +L +P DS +
Sbjct: 4 GMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSA-RP-MLEGVKYLCIPAADSPSQ 61
Query: 218 KILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEK 277
+ +S+ FI + + LVHCLAG+SRS T+ IAYIM D ++A V+
Sbjct: 62 NLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAG 121
Query: 278 RPTISPNFNFLGQLLDYEK 296
R +PN F QL ++EK
Sbjct: 122 RSCANPNVGFQRQLQEFEK 140
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 81.3 bits (199), Expect = 3e-15
Identities = 50/140 (35%), Positives = 79/140 (56%), Gaps = 6/140 (4%)
Query: 162 ILPNLYLGCQRDVLNKEL--MQQNGIGYVL----NASNTCPKPDFIPESHFLRVPVNDSF 215
ILP L+LG + +L +Q++GI +++ N KP+F +L + + D+
Sbjct: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
Query: 216 CEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVK 275
E I+ + + +FI+ + G VLVH AGISRSA IAYIM+ M +A+ +V+
Sbjct: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
Query: 276 EKRPTISPNFNFLGQLLDYE 295
E+R I+PN F+ QL +YE
Sbjct: 152 ERRFCINPNAGFVHQLQEYE 171
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 81.3 bits (199), Expect = 3e-15
Identities = 50/140 (35%), Positives = 79/140 (56%), Gaps = 6/140 (4%)
Query: 162 ILPNLYLGCQRDVLNKEL--MQQNGIGYVL----NASNTCPKPDFIPESHFLRVPVNDSF 215
ILP L+LG + +L +Q++GI +++ N KP+F +L + + D+
Sbjct: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
Query: 216 CEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVK 275
E I+ + + +FI+ + G VLVH AGISRSA IAYIM+ M +A+ +V+
Sbjct: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
Query: 276 EKRPTISPNFNFLGQLLDYE 295
E+R I+PN F+ QL +YE
Sbjct: 152 ERRFCINPNAGFVHQLQEYE 171
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 81.3 bits (199), Expect = 3e-15
Identities = 50/140 (35%), Positives = 79/140 (56%), Gaps = 6/140 (4%)
Query: 162 ILPNLYLGCQRDVLNKEL--MQQNGIGYVL----NASNTCPKPDFIPESHFLRVPVNDSF 215
ILP L+LG + +L +Q++GI +++ N KP+F +L + + D+
Sbjct: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
Query: 216 CEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVK 275
E I+ + + +FI+ + G VLVH AGISRSA IAYIM+ M +A+ +V+
Sbjct: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
Query: 276 EKRPTISPNFNFLGQLLDYE 295
E+R I+PN F+ QL +YE
Sbjct: 152 ERRFCINPNAGFVHQLQEYE 171
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 81.3 bits (199), Expect = 3e-15
Identities = 48/138 (34%), Positives = 73/138 (52%), Gaps = 1/138 (0%)
Query: 158 GPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCE 217
G ++I +LY+ NK ++ N I V+N S + + +++VPV DS
Sbjct: 19 GLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLY-EDIQYMQVPVADSPNS 77
Query: 218 KILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEK 277
++ + D D I + G L+HC AG+SRSA + +AY+MK MSL +A+ + K
Sbjct: 78 RLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSC 137
Query: 278 RPTISPNFNFLGQLLDYE 295
RP I PN F QL+ YE
Sbjct: 138 RPIIRPNSGFWEQLIHYE 155
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 80.1 bits (196), Expect = 6e-15
Identities = 61/202 (30%), Positives = 97/202 (48%), Gaps = 8/202 (3%)
Query: 158 GPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCE 217
G T++LP LYLG D + + + +N I ++++ + P+P + + +LR+PV D+
Sbjct: 4 GMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHES-PQP-LLQDITYLRIPVADTPEV 61
Query: 218 KILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEK 277
I + ++FI + + G LVHC AGISRS TI AY+M + + +K
Sbjct: 62 PIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKAT 121
Query: 278 RPTISPNFNFLGQLLDY----EKKIKNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKS 333
RP +PN F QL ++ +K++ Q +S + E+ +P Q S
Sbjct: 122 RPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFR--DEEELRALLPLCKRCRQGS 179
Query: 334 ETPLSPPCADSATSEAAGQRPV 355
T S SA SE QR V
Sbjct: 180 ATSASSAGPHSAASEGTVQRLV 201
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 79.7 bits (195), Expect = 8e-15
Identities = 45/135 (33%), Positives = 73/135 (54%), Gaps = 1/135 (0%)
Query: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILP 221
I P L LG Q + + +++N + ++LN + F+ + + + + D IL
Sbjct: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENA-FLSDFTYKSISILDLPETNILS 127
Query: 222 WLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTI 281
+ + +FIE+AK +G VLVHC AG+SR+A I I ++M S A+ VK RP+I
Sbjct: 128 YFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSI 187
Query: 282 SPNFNFLGQLLDYEK 296
PN F+ QL Y++
Sbjct: 188 CPNSGFMEQLRTYQE 202
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/145 (35%), Positives = 83/145 (57%), Gaps = 10/145 (6%)
Query: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESH------FLRVPVNDSF 215
+ P LYLG Q N+ +++ GI +VLNAS++ + PE++ +L V +DS
Sbjct: 65 VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGT--PEAYEGLGIRYLGVEAHDSP 122
Query: 216 CEKILPWLDKSVDFIEKAKAS-NGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFV 274
+ + DFI +A + G +LVHC G+SRSAT+ +AY+M ++L EA + V
Sbjct: 123 AFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKV 182
Query: 275 KEKRPTISPNFNFLGQLLDYEKKIK 299
K+ R I PN FL QLL +++++
Sbjct: 183 KDHRGII-PNRGFLRQLLALDRRLR 206
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,586,073
Number of Sequences: 37866
Number of extensions: 1224071
Number of successful extensions: 4451
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 4143
Number of HSP's gapped (non-prelim): 389
length of query: 665
length of database: 18,247,518
effective HSP length: 109
effective length of query: 556
effective length of database: 14,120,124
effective search space: 7850788944
effective search space used: 7850788944
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.