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Search of human proteins with 37674210
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37674210 slingshot 2 [Homo sapiens]
(1423 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37674210 slingshot 2 [Homo sapiens] 2872 0.0
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 678 0.0
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 678 0.0
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 647 0.0
gi|239582767 slingshot homolog 3 [Homo sapiens] 422 e-117
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 110 7e-24
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 107 8e-23
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 103 9e-22
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 100 2e-20
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 99 2e-20
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 99 2e-20
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 99 3e-20
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 97 1e-19
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 96 3e-19
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 91 6e-18
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 91 6e-18
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 90 2e-17
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 89 2e-17
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 89 4e-17
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 86 3e-16
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 86 3e-16
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 86 3e-16
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 85 4e-16
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 85 4e-16
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 76 2e-13
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 74 1e-12
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 71 6e-12
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 67 9e-11
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 66 2e-10
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 66 3e-10
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 2872 bits (7445), Expect = 0.0
Identities = 1423/1423 (100%), Positives = 1423/1423 (100%)
Query: 1 MALVTVQRSPTPSTTSSPCASEADSGEEECRSQPRSISESFLTVKGAALFLPRGNGSSTP 60
MALVTVQRSPTPSTTSSPCASEADSGEEECRSQPRSISESFLTVKGAALFLPRGNGSSTP
Sbjct: 1 MALVTVQRSPTPSTTSSPCASEADSGEEECRSQPRSISESFLTVKGAALFLPRGNGSSTP 60
Query: 61 RISHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEE 120
RISHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEE
Sbjct: 61 RISHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEE 120
Query: 121 SIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSA 180
SIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSA
Sbjct: 121 SIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSA 180
Query: 181 LQSLHKACEVARAHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALF 240
LQSLHKACEVARAHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALF
Sbjct: 181 LQSLHKACEVARAHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALF 240
Query: 241 TDIPTERERTERLIKTKLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIV 300
TDIPTERERTERLIKTKLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIV
Sbjct: 241 TDIPTERERTERLIKTKLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIV 300
Query: 301 ILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVY 360
ILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVY
Sbjct: 301 ILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVY 360
Query: 361 DEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYD 420
DEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYD
Sbjct: 361 DEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYD 420
Query: 421 YVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELN 480
YVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELN
Sbjct: 421 YVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELN 480
Query: 481 KKDITTSADQIAEVKTMESHPPIPPVFVEHMVPQDANQKGLCTKERMICLEFTSREFHAG 540
KKDITTSADQIAEVKTMESHPPIPPVFVEHMVPQDANQKGLCTKERMICLEFTSREFHAG
Sbjct: 481 KKDITTSADQIAEVKTMESHPPIPPVFVEHMVPQDANQKGLCTKERMICLEFTSREFHAG 540
Query: 541 QIEDELNLNDINGCSSGCCLNESKFPLDNCHASKALIQPGHVPEMANKFPDLTVEDLETD 600
QIEDELNLNDINGCSSGCCLNESKFPLDNCHASKALIQPGHVPEMANKFPDLTVEDLETD
Sbjct: 541 QIEDELNLNDINGCSSGCCLNESKFPLDNCHASKALIQPGHVPEMANKFPDLTVEDLETD 600
Query: 601 ALKADMNVHLLPMEELTSPLKDPPMSPDPESPSPQPSCQTEISDFSTDRIDFFSALEKFV 660
ALKADMNVHLLPMEELTSPLKDPPMSPDPESPSPQPSCQTEISDFSTDRIDFFSALEKFV
Sbjct: 601 ALKADMNVHLLPMEELTSPLKDPPMSPDPESPSPQPSCQTEISDFSTDRIDFFSALEKFV 660
Query: 661 ELSQETRSRSFSHSRMEELGGGRNESCRLSVVEVAPSKVTADDQRSSSLSNTPHASEESS 720
ELSQETRSRSFSHSRMEELGGGRNESCRLSVVEVAPSKVTADDQRSSSLSNTPHASEESS
Sbjct: 661 ELSQETRSRSFSHSRMEELGGGRNESCRLSVVEVAPSKVTADDQRSSSLSNTPHASEESS 720
Query: 721 MDEEQSKAISELVSPDIFMQSHSENAISVKEIVTEIESISQGVGQIQLKGDILPNPCHTP 780
MDEEQSKAISELVSPDIFMQSHSENAISVKEIVTEIESISQGVGQIQLKGDILPNPCHTP
Sbjct: 721 MDEEQSKAISELVSPDIFMQSHSENAISVKEIVTEIESISQGVGQIQLKGDILPNPCHTP 780
Query: 781 KKNSIHELLLERAQTPENKPGHMEQDEDSCTAQPELAKDSGMCNPEGCLTTHSSIADLEE 840
KKNSIHELLLERAQTPENKPGHMEQDEDSCTAQPELAKDSGMCNPEGCLTTHSSIADLEE
Sbjct: 781 KKNSIHELLLERAQTPENKPGHMEQDEDSCTAQPELAKDSGMCNPEGCLTTHSSIADLEE 840
Query: 841 GEPAEGEQELQGSGMHPGAKWYPGSVRRATLEFEERLRQEQEHHGAAPTCTSLSTRKNSK 900
GEPAEGEQELQGSGMHPGAKWYPGSVRRATLEFEERLRQEQEHHGAAPTCTSLSTRKNSK
Sbjct: 841 GEPAEGEQELQGSGMHPGAKWYPGSVRRATLEFEERLRQEQEHHGAAPTCTSLSTRKNSK 900
Query: 901 NDSSVADLAPKGKSDEAPPEHSFVLKEPEMSKGKGKYSGSEAGSLSHSEQNATVPAPRVL 960
NDSSVADLAPKGKSDEAPPEHSFVLKEPEMSKGKGKYSGSEAGSLSHSEQNATVPAPRVL
Sbjct: 901 NDSSVADLAPKGKSDEAPPEHSFVLKEPEMSKGKGKYSGSEAGSLSHSEQNATVPAPRVL 960
Query: 961 EFDHLPDPQEGPGSDTGTQQEGVLKDLRTVIPYQESETQAVPLPLPKRVEIIEYTHIVTS 1020
EFDHLPDPQEGPGSDTGTQQEGVLKDLRTVIPYQESETQAVPLPLPKRVEIIEYTHIVTS
Sbjct: 961 EFDHLPDPQEGPGSDTGTQQEGVLKDLRTVIPYQESETQAVPLPLPKRVEIIEYTHIVTS 1020
Query: 1021 PNHTGPGSEIATSEKSGEQGLRKVNMEKSVTVLCTLDENLNRTLDPNQVSLHPQVLPLPH 1080
PNHTGPGSEIATSEKSGEQGLRKVNMEKSVTVLCTLDENLNRTLDPNQVSLHPQVLPLPH
Sbjct: 1021 PNHTGPGSEIATSEKSGEQGLRKVNMEKSVTVLCTLDENLNRTLDPNQVSLHPQVLPLPH 1080
Query: 1081 SSSPEHNRPTDHPTSILSSPEDRGSSLSTALETAAPFVSHTTHLLSASLDYLHPQTMVHL 1140
SSSPEHNRPTDHPTSILSSPEDRGSSLSTALETAAPFVSHTTHLLSASLDYLHPQTMVHL
Sbjct: 1081 SSSPEHNRPTDHPTSILSSPEDRGSSLSTALETAAPFVSHTTHLLSASLDYLHPQTMVHL 1140
Query: 1141 EGFTEQSSTTDEPSAEQVSWEESQESPLSSGSEVPYKDSQLSSADLSLISKLGDNTGELQ 1200
EGFTEQSSTTDEPSAEQVSWEESQESPLSSGSEVPYKDSQLSSADLSLISKLGDNTGELQ
Sbjct: 1141 EGFTEQSSTTDEPSAEQVSWEESQESPLSSGSEVPYKDSQLSSADLSLISKLGDNTGELQ 1200
Query: 1201 EKMDPLPVACRLPHSSSSENIKSLSHSPGVVKERAKEIESRVVFQAGLTKPSQMRRSASL 1260
EKMDPLPVACRLPHSSSSENIKSLSHSPGVVKERAKEIESRVVFQAGLTKPSQMRRSASL
Sbjct: 1201 EKMDPLPVACRLPHSSSSENIKSLSHSPGVVKERAKEIESRVVFQAGLTKPSQMRRSASL 1260
Query: 1261 AKLGYLDLCKDCLPEREPASCESPHLKLLQPFLRTDSGMHAMEDQESLENPGAPHNPEPT 1320
AKLGYLDLCKDCLPEREPASCESPHLKLLQPFLRTDSGMHAMEDQESLENPGAPHNPEPT
Sbjct: 1261 AKLGYLDLCKDCLPEREPASCESPHLKLLQPFLRTDSGMHAMEDQESLENPGAPHNPEPT 1320
Query: 1321 KSFVEQLTTTECIVQSKPVERPLVQYAKEFGSSQQYLLPRAGLELTSSEGGLPVLQTQGL 1380
KSFVEQLTTTECIVQSKPVERPLVQYAKEFGSSQQYLLPRAGLELTSSEGGLPVLQTQGL
Sbjct: 1321 KSFVEQLTTTECIVQSKPVERPLVQYAKEFGSSQQYLLPRAGLELTSSEGGLPVLQTQGL 1380
Query: 1381 QCACPAPGLAVAPRQQHGRTHPLRRLKKANDKKRTTNPFYNTM 1423
QCACPAPGLAVAPRQQHGRTHPLRRLKKANDKKRTTNPFYNTM
Sbjct: 1381 QCACPAPGLAVAPRQQHGRTHPLRRLKKANDKKRTTNPFYNTM 1423
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 678 bits (1750), Expect = 0.0
Identities = 341/511 (66%), Positives = 402/511 (78%), Gaps = 4/511 (0%)
Query: 1 MALVTVQRSPTPSTTSSPCA-SEADSGEEECRSQPRSISESFLTVKGAALFLPRGNGSST 59
MALVT+QRSPTPS SS + SE ++G EE R S+SESF VKGAALFL +G+
Sbjct: 1 MALVTLQRSPTPSAASSSASNSELEAGSEEDRKLNLSLSESFFMVKGAALFLQQGSSPQG 60
Query: 60 PRISHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTE 119
R +KHAGDL QHLQ M LLR ED I+LAVRLES + +R RYMVVV ++GRQDTE
Sbjct: 61 QRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRLESAWADRVRYMVVVYSSGRQDTE 120
Query: 120 ESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWS 179
E+I+LG+DFSS +S +CT+G+VL LWSDT IHLDGDGGFSVST R+HIFKPVSVQAMWS
Sbjct: 121 ENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDGGFSVSTAGRMHIFKPVSVQAMWS 180
Query: 180 ALQSLHKACEVARAHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPAL 239
ALQ LHKACEVAR HNY+PG + L W +YYES I+S+QS +NEWNAMQD++S RPDSPAL
Sbjct: 181 ALQVLHKACEVARRHNYFPGGVALIWATYYESCISSEQSCINEWNAMQDLESTRPDSPAL 240
Query: 240 FTDIPTERERTERLIKTKLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMI 299
F D PTE ERTERLIK KLR IMM +DLEN+TSKEIR ELE QM CNL+E KEFIDNEM+
Sbjct: 241 FVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIRNELEKQMNCNLKELKEFIDNEML 300
Query: 300 VILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRV 359
+ILGQMD P+ IF+H++LGSEWNASNLE+LQ GV YILNVTREIDNFFPG+F YHNIRV
Sbjct: 301 LILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRV 360
Query: 360 YDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAY 419
YDEE TDLLA+WN+ Y FI+KAK++ SKCLVHCKMGVSRSASTVIAYAMKE+GW L++AY
Sbjct: 361 YDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAY 420
Query: 420 DYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLEL 479
+YVK++R++T+PN FMRQL EY+GIL ASKQRHNKLWR +DS L + PG L
Sbjct: 421 NYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFL 480
Query: 480 NKKDITTSADQIA---EVKTMESHPPIPPVF 507
+ T Q+ + PP+P F
Sbjct: 481 PETPDGTPESQLPFLDDAAQPGLGPPLPCCF 511
Score = 55.5 bits (132), Expect = 4e-07
Identities = 43/118 (36%), Positives = 60/118 (50%), Gaps = 6/118 (5%)
Query: 1208 VACRLPHSSSSENIKSLSHSPGVVKERAKEIESRVVFQAGLTKPSQMRRSASLAKLGYLD 1267
++ L SSSS++I S+ PG+VK+R +EIE+R+ AGLT S ++RS SLAKLG L
Sbjct: 928 MSSNLTRSSSSDSIHSVRGKPGLVKQRTQEIETRLRL-AGLTVSSPLKRSHSLAKLGSLT 986
Query: 1268 L-CKDCLPEREPASCESPHLKLL--QPFLRTDSGMHAMEDQESLENPGAPHNPEPTKS 1322
+D E +P++ L FL G D + P PE KS
Sbjct: 987 FSTEDLSSEADPSTVADSQDTTLSESSFLHEPQG--TPRDPAATSKPSGKPAPENLKS 1042
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 678 bits (1750), Expect = 0.0
Identities = 341/511 (66%), Positives = 402/511 (78%), Gaps = 4/511 (0%)
Query: 1 MALVTVQRSPTPSTTSSPCA-SEADSGEEECRSQPRSISESFLTVKGAALFLPRGNGSST 59
MALVT+QRSPTPS SS + SE ++G EE R S+SESF VKGAALFL +G+
Sbjct: 1 MALVTLQRSPTPSAASSSASNSELEAGSEEDRKLNLSLSESFFMVKGAALFLQQGSSPQG 60
Query: 60 PRISHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTE 119
R +KHAGDL QHLQ M LLR ED I+LAVRLES + +R RYMVVV ++GRQDTE
Sbjct: 61 QRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRLESAWADRVRYMVVVYSSGRQDTE 120
Query: 120 ESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWS 179
E+I+LG+DFSS +S +CT+G+VL LWSDT IHLDGDGGFSVST R+HIFKPVSVQAMWS
Sbjct: 121 ENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDGGFSVSTAGRMHIFKPVSVQAMWS 180
Query: 180 ALQSLHKACEVARAHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPAL 239
ALQ LHKACEVAR HNY+PG + L W +YYES I+S+QS +NEWNAMQD++S RPDSPAL
Sbjct: 181 ALQVLHKACEVARRHNYFPGGVALIWATYYESCISSEQSCINEWNAMQDLESTRPDSPAL 240
Query: 240 FTDIPTERERTERLIKTKLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMI 299
F D PTE ERTERLIK KLR IMM +DLEN+TSKEIR ELE QM CNL+E KEFIDNEM+
Sbjct: 241 FVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIRNELEKQMNCNLKELKEFIDNEML 300
Query: 300 VILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRV 359
+ILGQMD P+ IF+H++LGSEWNASNLE+LQ GV YILNVTREIDNFFPG+F YHNIRV
Sbjct: 301 LILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRV 360
Query: 360 YDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAY 419
YDEE TDLLA+WN+ Y FI+KAK++ SKCLVHCKMGVSRSASTVIAYAMKE+GW L++AY
Sbjct: 361 YDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAY 420
Query: 420 DYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLEL 479
+YVK++R++T+PN FMRQL EY+GIL ASKQRHNKLWR +DS L + PG L
Sbjct: 421 NYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFL 480
Query: 480 NKKDITTSADQIA---EVKTMESHPPIPPVF 507
+ T Q+ + PP+P F
Sbjct: 481 PETPDGTPESQLPFLDDAAQPGLGPPLPCCF 511
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 647 bits (1668), Expect = 0.0
Identities = 321/479 (67%), Positives = 378/479 (78%), Gaps = 3/479 (0%)
Query: 32 SQPRSISESFLTVKGAALFLPRGNGSSTPRISHRRNKHAGDLQQHLQAMFILLRPEDNIR 91
S +SESF VKGAALFL +G+ R +KHAGDL QHLQ M LLR ED I+
Sbjct: 44 SSSNYLSESFFMVKGAALFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIK 103
Query: 92 LAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIH 151
LAVRLES + +R RYMVVV ++GRQDTEE+I+LG+DFSS +S +CT+G+VL LWSDT IH
Sbjct: 104 LAVRLESAWADRVRYMVVVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIH 163
Query: 152 LDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARAHNYYPGSLFLTWVSYYES 211
LDGDGGFSVST R+HIFKPVSVQAMWSALQ LHKACEVAR HNY+PG + L W +YYES
Sbjct: 164 LDGDGGFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYES 223
Query: 212 HINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENIT 271
I+S+QS +NEWNAMQD++S RPDSPALF D PTE ERTERLIK KLR IMM +DLEN+T
Sbjct: 224 CISSEQSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVT 283
Query: 272 SKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQN 331
SKEIR ELE QM CNL+E KEFIDNEM++ILGQMD P+ IF+H++LGSEWNASNLE+LQ
Sbjct: 284 SKEIRNELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQG 343
Query: 332 RGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVH 391
GV YILNVTREIDNFFPG+F YHNIRVYDEE TDLLA+WN+ Y FI+KAK++ SKCLVH
Sbjct: 344 SGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVH 403
Query: 392 CKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQ 451
CKMGVSRSASTVIAYAMKE+GW L++AY+YVK++R++T+PN FMRQL EY+GIL ASKQ
Sbjct: 404 CKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQ 463
Query: 452 RHNKLWRSHSDSDLSDHHEPICKPGLELNKKDITTSADQIA---EVKTMESHPPIPPVF 507
RHNKLWR +DS L + PG L + T Q+ + PP+P F
Sbjct: 464 RHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCF 522
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 422 bits (1085), Expect = e-117
Identities = 217/479 (45%), Positives = 315/479 (65%), Gaps = 31/479 (6%)
Query: 1 MALVTVQRSPTPSTTSSPCASEADSGEEECRSQPRSISESFLTVKGAALFLPRG------ 54
MALVTV RSP S S+P + + R Q R +SF ++GA L L G
Sbjct: 1 MALVTVSRSPPGSGASTPVGPWDQAVQRRSRLQRR---QSFAVLRGAVLGLQDGGDNDDA 57
Query: 55 ---NGSSTPRISHRRNKHAG---------------DLQQHLQAMFILLRPEDNIRLAVRL 96
+ T + H + +QHL M LLRP+D+IRLA +L
Sbjct: 58 AEASSEPTEKAPSEEELHGDQTDFGQGSQSPQKQEEQRQHLHLMVQLLRPQDDIRLAAQL 117
Query: 97 ESTYQNRTRYMVVVSTNGRQ--DTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDG 154
E+ R RY++VVST + +E+++LG+DF + S +CT+GLVLPLWSDT ++LDG
Sbjct: 118 EAPRPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSSPSCTLGLVLPLWSDTQVYLDG 177
Query: 155 DGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARAHNYYPGSLFLTWVSYYESHIN 214
DGGFSV++ + IFKP+S+Q MW+ LQ LH+ACE A PG LTW S+Y+ +N
Sbjct: 178 DGGFSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQERLN 237
Query: 215 SDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENITSKE 274
S+QS +NEW AM D++S RP P+ +E+E+ E+ I+ +L +++ DLE++TSKE
Sbjct: 238 SEQSCLNEWTAMADLESLRP--PSAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVTSKE 295
Query: 275 IRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGV 334
IR LE+++ L+++++FIDN+M++++ Q D ++IF H++LGSEWNA+NLE+LQ V
Sbjct: 296 IRQALELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRV 355
Query: 335 RYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKM 394
+ILN+ REIDNF+P F YHN+R++DEE+ LL +W +T++FI A+ G+ LVHCKM
Sbjct: 356 THILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKM 415
Query: 395 GVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQRH 453
GVSRSA+TV+AYAMK+Y +L++A +V+E R + +PNP F+RQL+ YQGIL AS+Q H
Sbjct: 416 GVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSH 474
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 110 bits (276), Expect = 7e-24
Identities = 55/136 (40%), Positives = 85/136 (62%)
Query: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDL 367
P +I ++FLGS ++S+L+ LQ G+ +LNV+ N F G+F Y +I V D + ++
Sbjct: 173 PVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEI 232
Query: 368 LAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRT 427
A++ + FI K G + LVHC+ G+SRSA+ +AY M+ LD A+D+VK+RR
Sbjct: 233 SAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRG 292
Query: 428 VTKPNPSFMRQLEEYQ 443
V PN SFM QL +++
Sbjct: 293 VISPNFSFMGQLLQFE 308
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 107 bits (267), Expect = 8e-23
Identities = 51/141 (36%), Positives = 85/141 (60%)
Query: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDL 367
P +I ++LGS ++AS + L G+ ++NV+ N F G ++Y +I V D D+
Sbjct: 174 PVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADI 233
Query: 368 LAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRT 427
+++N+ FI K G + VHC+ G+SRSA+ +AY M+ LD A+++VK+RR+
Sbjct: 234 SSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRS 293
Query: 428 VTKPNPSFMRQLEEYQGILLA 448
+ PN SFM QL +++ +LA
Sbjct: 294 IISPNFSFMGQLLQFESQVLA 314
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 103 bits (258), Expect = 9e-22
Identities = 57/150 (38%), Positives = 90/150 (60%), Gaps = 3/150 (2%)
Query: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFP--GVFEYHNIRVYDEEAT 365
P QI +++LGS +++NLE L G+RYILNVT + NFF G F Y I + D +
Sbjct: 204 PVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQ 263
Query: 366 DLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKER 425
+L ++ + +FI +A LVHC GVSRS + +AY M++ +L+ AYD VK +
Sbjct: 264 NLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRK 323
Query: 426 RTVTKPNPSFMRQLEEYQGILLASKQRHNK 455
++ PN +FM QL +++ L ++RH++
Sbjct: 324 KSNISPNFNFMGQLLDFER-SLRLEERHSQ 352
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 99.8 bits (247), Expect = 2e-20
Identities = 50/137 (36%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Query: 309 TQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREID--NFFPGVFEYHNIRVYDEEATD 366
T I +FLG+E +A +L+ +Q + Y++NVT + ++ G+F Y + D +
Sbjct: 323 TPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQN 382
Query: 367 LLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERR 426
L Y+ + ++FI +A + G L+HC+ GVSRSA+ VIAY MK + AY +VK +R
Sbjct: 383 LRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKR 442
Query: 427 TVTKPNPSFMRQLEEYQ 443
+ PN +FM QL E++
Sbjct: 443 PIISPNLNFMGQLLEFE 459
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 99.4 bits (246), Expect = 2e-20
Identities = 49/148 (33%), Positives = 87/148 (58%)
Query: 302 LGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYD 361
L P +I ++LGS ++A+ + L G+ +LNV+ + N F G ++Y I V D
Sbjct: 190 LHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVED 249
Query: 362 EEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDY 421
D+ +++ + ++I K + LVHC+ G+SRSA+ +AY M + L+ A+++
Sbjct: 250 NHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 309
Query: 422 VKERRTVTKPNPSFMRQLEEYQGILLAS 449
VK+RR++ PN SFM QL +++ +LA+
Sbjct: 310 VKQRRSIISPNFSFMGQLLQFESQVLAT 337
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 99.4 bits (246), Expect = 2e-20
Identities = 49/148 (33%), Positives = 87/148 (58%)
Query: 302 LGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYD 361
L P +I ++LGS ++A+ + L G+ +LNV+ + N F G ++Y I V D
Sbjct: 99 LHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVED 158
Query: 362 EEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDY 421
D+ +++ + ++I K + LVHC+ G+SRSA+ +AY M + L+ A+++
Sbjct: 159 NHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 218
Query: 422 VKERRTVTKPNPSFMRQLEEYQGILLAS 449
VK+RR++ PN SFM QL +++ +LA+
Sbjct: 219 VKQRRSIISPNFSFMGQLLQFESQVLAT 246
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 99.0 bits (245), Expect = 3e-20
Identities = 51/142 (35%), Positives = 79/142 (55%)
Query: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDL 367
P +I ++LGS ++AS E L N + +LNV+R Y I V D D+
Sbjct: 179 PVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADI 238
Query: 368 LAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRT 427
+++ + FI ++ G K LVHC+ G+SRS + +AY MK + L A+DY+K+RR+
Sbjct: 239 SSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRS 298
Query: 428 VTKPNPSFMRQLEEYQGILLAS 449
+ PN FM QL +Y+ +L S
Sbjct: 299 MVSPNFGFMGQLLQYESEILPS 320
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 96.7 bits (239), Expect = 1e-19
Identities = 50/141 (35%), Positives = 83/141 (58%), Gaps = 2/141 (1%)
Query: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFP--GVFEYHNIRVYDEEAT 365
P QI +++LG +++NL+ L G++YILNVT + N F G F Y I + D +
Sbjct: 245 PVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQ 304
Query: 366 DLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKER 425
+L ++ + FI +A+ LVHC G+SRS + +AY M++ +L+ AYD+VK +
Sbjct: 305 NLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRK 364
Query: 426 RTVTKPNPSFMRQLEEYQGIL 446
++ PN +FM QL +++ L
Sbjct: 365 KSNISPNFNFMGQLLDFERTL 385
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 95.5 bits (236), Expect = 3e-19
Identities = 51/155 (32%), Positives = 88/155 (56%), Gaps = 2/155 (1%)
Query: 304 QMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFP--GVFEYHNIRVYD 361
Q P +I ++LG +++NL+ L+ G++YILNVT + N F G F+Y I + D
Sbjct: 203 QPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISD 262
Query: 362 EEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDY 421
+ +L ++ + FI +A+ LVHC G+SRS + +AY M++ +++ AYD
Sbjct: 263 HWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDI 322
Query: 422 VKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKL 456
VK +++ PN +FM QL +++ L S N++
Sbjct: 323 VKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRV 357
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 91.3 bits (225), Expect = 6e-18
Identities = 94/350 (26%), Positives = 146/350 (41%), Gaps = 52/350 (14%)
Query: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREID--NFFPGVFEYHNIRV--YDEE 363
PT+I +++LG + + N E +Q G+ Y+LN + +F P E H +RV D
Sbjct: 159 PTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIP---ESHFLRVPVNDSF 215
Query: 364 ATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVK 423
+L + + + FI KAK LVHC G+SRSA+ IAY MK +LD AY +VK
Sbjct: 216 CEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVK 275
Query: 424 ERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHH-----EPICKPGL- 477
E+R PN +F+ QL +Y+ K+ N+ S S L H EP+ P +
Sbjct: 276 EKRPTISPNFNFLGQLLDYE------KKIKNQTGASGPKSKLKLLHLEKPNEPV--PAVS 327
Query: 478 ELNKKDITTSADQIAEVKTMES--HPPIPPVFVEHMVPQDANQKGLCTKERMICLEFTSR 535
E +K T + A+ T E+ P+ P VP + + ++ + +
Sbjct: 328 EGGQKSETPLSPPCADSATSEAAGQRPVHPA----SVPSVPSVQPSLLEDSPLVQALSGL 383
Query: 536 EFHAGQIEDELNLN-----DINGCSSGCCLNESKFPLDNCHASKALIQPGHVPEMANKFP 590
A ++ED L DI S + S + + +P + NK
Sbjct: 384 HLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYKPSTTLDGTNKLC 443
Query: 591 DLTVEDLETDALKADMNVHLLPMEELTSPLKDPPMSPDPESPSPQPSCQT 640
+ P++EL+ + P SPD E S QT
Sbjct: 444 QFS------------------PVQELSE--QTPETSPDKEEASIPKKLQT 473
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 91.3 bits (225), Expect = 6e-18
Identities = 60/142 (42%), Positives = 79/142 (55%), Gaps = 2/142 (1%)
Query: 303 GQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDE 362
G + QI +FLG ASN LQ RG+ I+N T EI NF FEY + + D
Sbjct: 22 GDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADM 81
Query: 363 EATDLLAYWNDTY-KFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDY 421
+ Y++ K S ++KHG+ LVHC GVSRSA+ IAY MK + L AY++
Sbjct: 82 PHAPIGLYFDTVADKIHSVSRKHGAT-LVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNW 140
Query: 422 VKERRTVTKPNPSFMRQLEEYQ 443
VK RR V +PN F RQL +Y+
Sbjct: 141 VKARRPVIRPNVGFWRQLIDYE 162
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 89.7 bits (221), Expect = 2e-17
Identities = 48/129 (37%), Positives = 72/129 (55%)
Query: 315 VFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDT 374
+ LGS+ A +L+ L+ V +ILNV ++N F F Y +I + D T++L+Y+ +
Sbjct: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
Query: 375 YKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPS 434
++FI +AK+ LVHC GVSR+A+ VI + M + A+ VK R PN
Sbjct: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
Query: 435 FMRQLEEYQ 443
FM QL YQ
Sbjct: 193 FMEQLRTYQ 201
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 89.4 bits (220), Expect = 2e-17
Identities = 55/135 (40%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Query: 315 VFLGSEWNASNLEDLQNRGVRYILNVTREIDN-FFPGVFEYHNIRVYDEEATDLLAYWND 373
+FLGS A E L GV +NV+R+ PGV E + V+D+ A DLLA+
Sbjct: 26 LFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELR-VPVFDDPAEDLLAHLEP 84
Query: 374 TYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNP 433
T + A + G CLV+CK G SRSA+ AY M+ G +L +A+ VK R V +PNP
Sbjct: 85 TCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNP 144
Query: 434 SFMRQLEEYQGILLA 448
F QL++Y+ L A
Sbjct: 145 GFWSQLQKYEEALQA 159
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 88.6 bits (218), Expect = 4e-17
Identities = 48/136 (35%), Positives = 75/136 (55%), Gaps = 1/136 (0%)
Query: 309 TQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDN-FFPGVFEYHNIRVYDEEATDL 367
T+I H++LGS+ + N + + G+ Y+LN + F + + + D L
Sbjct: 162 TRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKL 221
Query: 368 LAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRT 427
L + + + +FI KAK + +VHC G+SRSA+ IAY MK G + D AY +VK+RR
Sbjct: 222 LPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRP 281
Query: 428 VTKPNPSFMRQLEEYQ 443
PN +F+ QL EY+
Sbjct: 282 SISPNFNFLGQLLEYE 297
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 85.9 bits (211), Expect = 3e-16
Identities = 53/146 (36%), Positives = 82/146 (56%), Gaps = 7/146 (4%)
Query: 310 QIFEHVFLGSEWNA--SNLEDLQNRGVRYILNVTREID-NF----FPGVFEYHNIRVYDE 362
+I +FLG +A S L LQ G+ +I+ + + I+ NF F +F Y + + D
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 363 EATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYV 422
+++ ++ T +FI + + G K LVH G+SRSA+ VIAY M+ +G A+ YV
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 423 KERRTVTKPNPSFMRQLEEYQGILLA 448
+ERR PN F+ QL+EY+ I LA
Sbjct: 151 QERRFCINPNAGFVHQLQEYEAIYLA 176
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 85.9 bits (211), Expect = 3e-16
Identities = 53/146 (36%), Positives = 82/146 (56%), Gaps = 7/146 (4%)
Query: 310 QIFEHVFLGSEWNA--SNLEDLQNRGVRYILNVTREID-NF----FPGVFEYHNIRVYDE 362
+I +FLG +A S L LQ G+ +I+ + + I+ NF F +F Y + + D
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 363 EATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYV 422
+++ ++ T +FI + + G K LVH G+SRSA+ VIAY M+ +G A+ YV
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 423 KERRTVTKPNPSFMRQLEEYQGILLA 448
+ERR PN F+ QL+EY+ I LA
Sbjct: 151 QERRFCINPNAGFVHQLQEYEAIYLA 176
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 85.9 bits (211), Expect = 3e-16
Identities = 53/146 (36%), Positives = 82/146 (56%), Gaps = 7/146 (4%)
Query: 310 QIFEHVFLGSEWNA--SNLEDLQNRGVRYILNVTREID-NF----FPGVFEYHNIRVYDE 362
+I +FLG +A S L LQ G+ +I+ + + I+ NF F +F Y + + D
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 363 EATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYV 422
+++ ++ T +FI + + G K LVH G+SRSA+ VIAY M+ +G A+ YV
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 423 KERRTVTKPNPSFMRQLEEYQGILLA 448
+ERR PN F+ QL+EY+ I LA
Sbjct: 151 QERRFCINPNAGFVHQLQEYEAIYLA 176
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 85.1 bits (209), Expect = 4e-16
Identities = 42/117 (35%), Positives = 68/117 (58%), Gaps = 2/117 (1%)
Query: 329 LQNRGVRYILNVTREID--NFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGS 386
+Q + Y++NVT + ++ G+F Y + D +L Y+ + ++FI +A + G
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 387 KCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQ 443
L+HC+ GVSRSA+ VIAY MK + AY +VK +R + PN +FM QL E++
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFE 117
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 85.1 bits (209), Expect = 4e-16
Identities = 42/117 (35%), Positives = 68/117 (58%), Gaps = 2/117 (1%)
Query: 329 LQNRGVRYILNVTREID--NFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGS 386
+Q + Y++NVT + ++ G+F Y + D +L Y+ + ++FI +A + G
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 387 KCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQ 443
L+HC+ GVSRSA+ VIAY MK + AY +VK +R + PN +FM QL E++
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFE 117
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 76.3 bits (186), Expect = 2e-13
Identities = 54/173 (31%), Positives = 86/173 (49%), Gaps = 10/173 (5%)
Query: 310 QIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLA 369
+I +++G+ +A + E L V +IL+V GV +Y I D + +L
Sbjct: 7 KILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGV-KYLCIPAADSPSQNLTR 65
Query: 370 YWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAM--KEYGWNLDRAYDYVKERRT 427
++ ++ KFI + + G CLVHC GVSRS + VIAY M ++GW + A V+ R+
Sbjct: 66 HFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGW--EDALHTVRAGRS 123
Query: 428 VTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEP---ICKPGL 477
PN F RQL+E++ + Q L + +S L D E + PG+
Sbjct: 124 CANPNVGFQRQLQEFEKHEV--HQYRQWLKEEYGESPLQDAEEAKNILAAPGI 174
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 73.9 bits (180), Expect = 1e-12
Identities = 46/171 (26%), Positives = 79/171 (46%), Gaps = 8/171 (4%)
Query: 309 TQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLL 368
T++ ++LG+ +A +L+ L + +I+++ + Y I V D +
Sbjct: 6 TKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDI-TYLRIPVADTPEVPIK 64
Query: 369 AYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTV 428
++ + FI + +G CLVHC G+SRS + V AY M G + +K R +
Sbjct: 65 KHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPI 124
Query: 429 TKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHE-----PICK 474
PNP F +QLEE+ +S++ +L +S D E P+CK
Sbjct: 125 ANPNPGFRQQLEEFG--WASSQKLRRQLEERFGESPFRDEEELRALLPLCK 173
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 71.2 bits (173), Expect = 6e-12
Identities = 44/136 (32%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Query: 310 QIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFE-----YHNIRVYDEEA 364
+++ ++LG + A+N +L+ G+ ++LN + P +E Y + +D A
Sbjct: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
Query: 365 TDLLAYWNDTYKFISKA-KKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVK 423
D+ ++ FI +A + G K LVHC +GVSRSA+ V+AY M + L A VK
Sbjct: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
Query: 424 ERRTVTKPNPSFMRQL 439
+ R + PN F+RQL
Sbjct: 184 DHRGII-PNRGFLRQL 198
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 67.4 bits (163), Expect = 9e-11
Identities = 41/135 (30%), Positives = 67/135 (49%)
Query: 309 TQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLL 368
+QI +FL + A++ L + + I+N + E+ N F +Y + V D + L
Sbjct: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLY 82
Query: 369 AYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTV 428
+++ I + L+HC GVSRSAS +AY MK + +L A+ + K RR +
Sbjct: 83 DFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPI 142
Query: 429 TKPNPSFMRQLEEYQ 443
+PN F QL Y+
Sbjct: 143 IRPNNGFWEQLINYE 157
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 66.2 bits (160), Expect = 2e-10
Identities = 43/137 (31%), Positives = 72/137 (52%), Gaps = 8/137 (5%)
Query: 310 QIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREI------DNFFPGVFEYHNIRVYDEE 363
+++ ++F+G A+N +L G+ ++LN + +F+ Y + +D
Sbjct: 40 EVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLP 99
Query: 364 ATDLLAYWNDTYKFISKA-KKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYV 422
D+ AY++ FI +A G+K LVHC +GVSRSA+ V+AY M +L +A V
Sbjct: 100 DFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITV 159
Query: 423 KERRTVTKPNPSFMRQL 439
++ R V PN F+ QL
Sbjct: 160 RQHRWVF-PNRGFLHQL 175
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 65.9 bits (159), Expect = 3e-10
Identities = 39/145 (26%), Positives = 70/145 (48%)
Query: 309 TQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLL 368
+QI + +++ + A+N L + + ++NV+ E+ N +Y + V D + L
Sbjct: 21 SQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLC 80
Query: 369 AYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTV 428
+++ I + + L+HC GVSRSA+ +AY MK + +L A+ + K R +
Sbjct: 81 DFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPI 140
Query: 429 TKPNPSFMRQLEEYQGILLASKQRH 453
+PN F QL Y+ L H
Sbjct: 141 IRPNSGFWEQLIHYEFQLFGKNTVH 165
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,009,587
Number of Sequences: 37866
Number of extensions: 3011185
Number of successful extensions: 10498
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 132
Number of HSP's that attempted gapping in prelim test: 10175
Number of HSP's gapped (non-prelim): 499
length of query: 1423
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1308
effective length of database: 13,892,928
effective search space: 18171949824
effective search space used: 18171949824
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.