Search of human proteins with 33942066

Search of human proteins with 33942066

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33942066 SUMO/sentrin specific peptidase family member 8
[Homo sapiens]
         (212 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33942066 SUMO/sentrin specific peptidase family member 8 [Hom...   435   e-122
gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens]         45   6e-05
gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens]      42   3e-04
gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens]             37   0.009
gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo ...    33   0.14 
gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo ...    33   0.14 
gi|239757770 PREDICTED: melanoma antigen family B, 5 [Homo sapiens]    30   2.0  
gi|169216202 PREDICTED: melanoma antigen family B, 5 [Homo sapiens]    30   2.0  
gi|169216811 PREDICTED: melanoma antigen family B, 5 [Homo sapiens]    30   2.0  
gi|5174547 mitogen-activated protein kinase kinase kinase 5 [Hom...    28   4.4  
gi|160420295 hypothetical protein LOC85459 [Homo sapiens]              28   4.4  
gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo sa...    28   5.7  
gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo sa...    28   5.7  
gi|115527120 nebulin [Homo sapiens]                                    28   5.7  
gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens]      28   5.7  
gi|28416956 GTPase, IMAP family member 8 [Homo sapiens]                28   5.7  

>gi|33942066 SUMO/sentrin specific peptidase family member 8 [Homo
           sapiens]
          Length = 212

 Score =  435 bits (1118), Expect = e-122
 Identities = 212/212 (100%), Positives = 212/212 (100%)

Query: 1   MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ 60
           MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
Sbjct: 1   MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ 60

Query: 61  FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS 120
           FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
Sbjct: 61  FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS 120

Query: 121 HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR 180
           HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
Sbjct: 121 HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR 180

Query: 181 QQTESLLQLLTPAYITKKRGEWKDLIATLAKK 212
           QQTESLLQLLTPAYITKKRGEWKDLIATLAKK
Sbjct: 181 QQTESLLQLLTPAYITKKRGEWKDLIATLAKK 212


>gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens]
          Length = 755

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 45/183 (24%), Positives = 75/183 (40%), Gaps = 28/183 (15%)

Query: 8   YMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSN 67
           Y   +L   D++ LD  +WLND +I    E   ++      D V F +    + +  T  
Sbjct: 564 YNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDA----VPDKVHFFNSFFHRQL-VTKG 618

Query: 68  PAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSV 127
              +  + + +DL  K ++ + I+          HWSL+           YD    S  +
Sbjct: 619 YNGVKRWTKKVDLFKKSLLLIPIHLE-------VHWSLITVTLSNRIISFYD----SQGI 667

Query: 128 HAKQVAEKLEAFL---GRKGDKLAF-------VEEKAPAQQNSYDCGMYVI--CNTEALC 175
           H K   E +  +L    R+ ++  F       V +  P Q+N  DCG++V+  C   AL 
Sbjct: 668 HFKFCVENIRKYLLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQYCKCLALE 727

Query: 176 QNF 178
           Q F
Sbjct: 728 QPF 730


>gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens]
          Length = 574

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 44/187 (23%), Positives = 79/187 (42%), Gaps = 23/187 (12%)

Query: 6   LSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCT 65
           ++Y   +L   D+  L   +WLND ++      + +       + V F +      ++ T
Sbjct: 381 VAYKRHVLTMDDLGTLYGQNWLNDQVMNM----YGDLVMDTVPEKVHFFNSFFYDKLR-T 435

Query: 66  SNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSN 125
                +  + + +D+ NK ++ + I+          HWSL+     + +  ++DS    N
Sbjct: 436 KGYDGVKRWTKNVDIFNKELLLIPIHLE-------VHWSLISVDVRRRTITYFDSQRTLN 488

Query: 126 SVHAKQVAEKLEAFLGRKGDKLAF-------VEEKAPAQQNSYDCGMYVI--CNTEALCQ 176
               K +A+ L+A   +K D+L F        +     Q N  DCG +V+  C   AL Q
Sbjct: 489 RRCPKHIAKYLQAEAVKK-DRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQ 547

Query: 177 NF-FRQQ 182
            F F QQ
Sbjct: 548 PFSFTQQ 554


>gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens]
          Length = 643

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 42/192 (21%), Positives = 72/192 (37%), Gaps = 20/192 (10%)

Query: 2   DPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQF 61
           D V+       + + D+  L+  +WLND II F                V   +      
Sbjct: 441 DEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTK 500

Query: 62  IKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSH 121
           +K T+    +  + + +D+ +  ++ + I+        G HW L V    K +  +YDS 
Sbjct: 501 LK-TAGYQAVKRWTKKVDVFSVDILLVPIHL-------GVHWCLAVVDFRKKNITYYDSM 552

Query: 122 SRSNSVHAK--------QVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGM----YVIC 169
              N+   +        +  +K        G +L   + + P Q N  DCGM    Y  C
Sbjct: 553 GGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQIPQQMNGSDCGMFACKYADC 612

Query: 170 NTEALCQNFFRQ 181
            T+    NF +Q
Sbjct: 613 ITKDRPINFTQQ 624


>gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo
            sapiens]
          Length = 1105

 Score = 33.5 bits (75), Expect = 0.14
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 12/98 (12%)

Query: 122  SRSNSVHAKQVAEKLEA-FLGRKGDKLAFVEE-------KAPAQQNSYDCGMYVICNTEA 173
            SRSN V  K + E LE  +  +KG K +F ++       K P Q N  DCG+YV+   E+
Sbjct: 976  SRSNVV--KILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVES 1033

Query: 174  LCQN--FFRQQTESLLQLLTPAYITKKRGEWKDLIATL 209
              +N     +   +L     P  +  KR E +++I  L
Sbjct: 1034 FFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKL 1071


>gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo
            sapiens]
          Length = 1112

 Score = 33.5 bits (75), Expect = 0.14
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 12/98 (12%)

Query: 122  SRSNSVHAKQVAEKLEA-FLGRKGDKLAFVEE-------KAPAQQNSYDCGMYVICNTEA 173
            SRSN V  K + E LE  +  +KG K +F ++       K P Q N  DCG+YV+   E+
Sbjct: 983  SRSNVV--KILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVES 1040

Query: 174  LCQN--FFRQQTESLLQLLTPAYITKKRGEWKDLIATL 209
              +N     +   +L     P  +  KR E +++I  L
Sbjct: 1041 FFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKL 1078


>gi|239757770 PREDICTED: melanoma antigen family B, 5 [Homo sapiens]
          Length = 367

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 16/56 (28%), Positives = 28/56 (50%)

Query: 151 EEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLI 206
           +E+A ++   Y C   V  +TE+ C NF   +   L Q L   +  K+R   +D++
Sbjct: 104 DERANSRDEEYPCSSEVSPSTESSCSNFINIKVGLLEQFLLYKFKMKQRILKEDML 159


>gi|169216202 PREDICTED: melanoma antigen family B, 5 [Homo sapiens]
          Length = 367

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 16/56 (28%), Positives = 28/56 (50%)

Query: 151 EEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLI 206
           +E+A ++   Y C   V  +TE+ C NF   +   L Q L   +  K+R   +D++
Sbjct: 104 DERANSRDEEYPCSSEVSPSTESSCSNFINIKVGLLEQFLLYKFKMKQRILKEDML 159


>gi|169216811 PREDICTED: melanoma antigen family B, 5 [Homo sapiens]
          Length = 367

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 16/56 (28%), Positives = 28/56 (50%)

Query: 151 EEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLI 206
           +E+A ++   Y C   V  +TE+ C NF   +   L Q L   +  K+R   +D++
Sbjct: 104 DERANSRDEEYPCSSEVSPSTESSCSNFINIKVGLLEQFLLYKFKMKQRILKEDML 159


>gi|5174547 mitogen-activated protein kinase kinase kinase 5 [Homo
           sapiens]
          Length = 1374

 Score = 28.5 bits (62), Expect = 4.4
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 8/77 (10%)

Query: 121 HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR 180
           H   +S   ++V  KL + LG+KG+      EK    Q+ ++ G ++  +  A       
Sbjct: 444 HQFESSFELRKVGVKLSSLLGKKGNL-----EKL---QSYWEVGFFLGASVLANDHMRVI 495

Query: 181 QQTESLLQLLTPAYITK 197
           Q +E L +L TPA+  K
Sbjct: 496 QASEKLFKLKTPAWYLK 512


>gi|160420295 hypothetical protein LOC85459 [Homo sapiens]
          Length = 2601

 Score = 28.5 bits (62), Expect = 4.4
 Identities = 15/44 (34%), Positives = 20/44 (45%)

Query: 119  DSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYD 162
            D+H  S    AKQ  E LE  LGR+  K    + K     N ++
Sbjct: 1804 DNHLASEDTSAKQSGEHLEKDLGRRSSKPPVAKVKCGLDLNQHE 1847


>gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo
           sapiens]
          Length = 985

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 10/63 (15%)

Query: 153 KAPAQQNSYDCGMYVICNTEALCQNFFRQQTESL-----LQLLTPAYITK-KRGEWKDLI 206
           K P Q NS DCG+Y++   E    +FF+    +      L+   P ++ K KR + ++LI
Sbjct: 917 KVPKQDNSSDCGVYLLQYVE----SFFKDPIVNFELPIHLEKWFPRHVIKTKREDIRELI 972

Query: 207 ATL 209
             L
Sbjct: 973 LKL 975


>gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo
            sapiens]
          Length = 1050

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 10/63 (15%)

Query: 153  KAPAQQNSYDCGMYVICNTEALCQNFFRQQTESL-----LQLLTPAYITK-KRGEWKDLI 206
            K P Q NS DCG+Y++   E    +FF+    +      L+   P ++ K KR + ++LI
Sbjct: 982  KVPKQDNSSDCGVYLLQYVE----SFFKDPIVNFELPIHLEKWFPRHVIKTKREDIRELI 1037

Query: 207  ATL 209
              L
Sbjct: 1038 LKL 1040


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 11/32 (34%), Positives = 17/32 (53%)

Query: 37  EYFANSQFHDCSDHVSFISPEVTQFIKCTSNP 68
           EY A  +   C DH   + P+ T+F + T +P
Sbjct: 478 EYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSP 509



 Score = 27.3 bits (59), Expect = 9.8
 Identities = 11/32 (34%), Positives = 16/32 (50%)

Query: 37  EYFANSQFHDCSDHVSFISPEVTQFIKCTSNP 68
           EY A  +   C DH   + P+ T+F   T +P
Sbjct: 725 EYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSP 756


>gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens]
          Length = 589

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 37/182 (20%), Positives = 70/182 (38%), Gaps = 33/182 (18%)

Query: 2   DPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFA--NSQFHDCSDHV--SFISPE 57
           D ++ S     + + D+  L    WLND +I F        N +    + HV  +F  P+
Sbjct: 386 DEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPK 445

Query: 58  VTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFH 117
           +      +     +  + + ++L  + ++ + I+          HWSL+V    K    +
Sbjct: 446 LK-----SGGYQAVKRWTKGVNLFEQEIILVPIHRK-------VHWSLVVIDLRKKCLKY 493

Query: 118 YDSHSRSNSVHAKQVAEKLEAFL-----GRKGDKLAFVE--------EKAPAQQNSYDCG 164
            DS  +       ++ E L  +L      ++   L  +E         + P Q N  DCG
Sbjct: 494 LDSMGQK----GHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCG 549

Query: 165 MY 166
           M+
Sbjct: 550 MF 551


>gi|28416956 GTPase, IMAP family member 8 [Homo sapiens]
          Length = 665

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 93  NSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEE 152
           NSN+A  G    L+   +++ S F+Y +        A ++ EK+E+ + + G+K     E
Sbjct: 380 NSNKALYG----LIQKCKNRYSAFNYRATGEEEQRQADELLEKIESMVHQNGNKHCVFRE 435

Query: 153 K 153
           K
Sbjct: 436 K 436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,947,972
Number of Sequences: 37866
Number of extensions: 316138
Number of successful extensions: 613
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 599
Number of HSP's gapped (non-prelim): 19
length of query: 212
length of database: 18,247,518
effective HSP length: 98
effective length of query: 114
effective length of database: 14,536,650
effective search space: 1657178100
effective search space used: 1657178100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.