Search of human proteins with 33636766

Search of human proteins with 33636766

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33636766 phospholysine phosphohistidine inorganic
pyrophosphate phosphatase [Homo sapiens]
         (270 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33636766 phospholysine phosphohistidine inorganic pyrophospha...   536   e-153
gi|14149777 haloacid dehalogenase-like hydrolase domain containi...   194   7e-50
gi|10092677 pyridoxal phosphatase [Homo sapiens]                       83   2e-16
gi|108796653 phosphoglycolate phosphatase [Homo sapiens]               75   8e-14
gi|23308749 N-acetylneuraminic acid phosphatase [Homo sapiens]         34   0.12 
gi|37674210 slingshot 2 [Homo sapiens]                                 30   1.7  
gi|13654294 haloacid dehalogenase-like hydrolase domain containi...    30   1.7  
gi|96303826 zinc finger protein 16 [Homo sapiens]                      29   4.9  
gi|38045954 zinc finger protein 16 [Homo sapiens]                      29   4.9  
gi|20270253 activating signal cointegrator 1 complex subunit 2 [...    28   6.5  
gi|12056463 coagulation factor VIII-associated protein [Homo sap...    28   8.4  
gi|56090586 coagulation factor VIII-associated (intronic transcr...    28   8.4  
gi|56090588 coagulation factor VIII-associated (intronic transcr...    28   8.4  

>gi|33636766 phospholysine phosphohistidine inorganic pyrophosphate
           phosphatase [Homo sapiens]
          Length = 270

 Score =  536 bits (1382), Expect = e-153
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 1   MAPWGKRLAGVRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESQKS 60
           MAPWGKRLAGVRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESQKS
Sbjct: 1   MAPWGKRLAGVRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESQKS 60

Query: 61  RAELVGQLQRLGFDISEQEVTAPAPAACQILKERGLRPYLLIHDGVRSEFDQIDTSNPNC 120
           RAELVGQLQRLGFDISEQEVTAPAPAACQILKERGLRPYLLIHDGVRSEFDQIDTSNPNC
Sbjct: 61  RAELVGQLQRLGFDISEQEVTAPAPAACQILKERGLRPYLLIHDGVRSEFDQIDTSNPNC 120

Query: 121 VVIADAGESFSYQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLMLDVGPYMKALEYAC 180
           VVIADAGESFSYQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLMLDVGPYMKALEYAC
Sbjct: 121 VVIADAGESFSYQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLMLDVGPYMKALEYAC 180

Query: 181 GIKAEVVGKPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRP 240
           GIKAEVVGKPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRP
Sbjct: 181 GIKAEVVGKPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRP 240

Query: 241 SDEHHPEVKADGYVDNLAEAVDLLLQHADK 270
           SDEHHPEVKADGYVDNLAEAVDLLLQHADK
Sbjct: 241 SDEHHPEVKADGYVDNLAEAVDLLLQHADK 270


>gi|14149777 haloacid dehalogenase-like hydrolase domain containing
           2 [Homo sapiens]
          Length = 259

 Score =  194 bits (493), Expect = 7e-50
 Identities = 111/257 (43%), Positives = 158/257 (61%), Gaps = 6/257 (2%)

Query: 11  VRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESQKSRAELVGQLQR 70
           ++ VL+D+SG L+   A    A+ G+ EA+ RL+ + + +RF TN +++S+ +L+ +L++
Sbjct: 7   LKAVLVDLSGTLHIEDA----AVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRK 62

Query: 71  LGFDISEQEVTAPAPAACQILKERGLRPYLLIHDGVRSEFDQIDTSNPNCVVIADAGESF 130
           L FDISE E+     AA  +L+ + +RP LL+ D    +F  I TS+PN VV+  A E F
Sbjct: 63  LEFDISEDEIFTSLTAARSLLERKQVRPMLLVDDRALPDFKGIQTSDPNAVVMGLAPEHF 122

Query: 131 SYQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLMLDVGPYMKALEYACGIKAEVVGKP 190
            YQ +N AF++L  L+   LI++ + RYYK   GL L  GP++ ALEYA   KA VVGKP
Sbjct: 123 HYQILNQAFRLL--LDGAPLIAIHKARYYKRKDGLALGPGPFVTALEYATDTKATVVGKP 180

Query: 191 SPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRPSDEHHPEVKA 250
              FF  AL+  G E  +AVMIGDD   DVGGAQ  GM  + V+TGK+R SDE       
Sbjct: 181 EKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGMLGILVKTGKYRASDEEKINPPP 240

Query: 251 DGYVDNLAEAVDLLLQH 267
               ++   AVD +LQH
Sbjct: 241 YLTCESFPHAVDHILQH 257


>gi|10092677 pyridoxal phosphatase [Homo sapiens]
          Length = 296

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 71/253 (28%), Positives = 120/253 (47%), Gaps = 26/253 (10%)

Query: 8   LAGVRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESQKSRAELVGQ 67
           L   +GVL D  GVL++    G  A+ G+ E + RL R+     F +N S+++R EL  +
Sbjct: 16  LGRAQGVLFDCDGVLWN----GERAVPGAPELLERLARAGKAALFVSNNSRRARPELALR 71

Query: 68  LQRLGFD-ISEQEVTAPAPAACQILKERGLRP-------YLLIHDGVRSEFDQI------ 113
             RLGF  +  +++ + A  A ++L++R   P       ++L  +G+R+E          
Sbjct: 72  FARLGFGGLRAEQLFSSALCAARLLRQRLPGPPDAPGAVFVLGGEGLRAELRAAGLRLAG 131

Query: 114 -----DTSNPNC-VVIADAGESFSYQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLML 167
                D + P    V+    E FS+  +  A   L + E  +L++  R  ++  + G   
Sbjct: 132 DPSAGDGAAPRVRAVLVGYDEHFSFAKLREACAHLRDPEC-LLVATDRDPWHPLSDGSRT 190

Query: 168 D-VGPYMKALEYACGIKAEVVGKPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRC 226
              G    A+E A G +A VVGKPSP  F+   +   ++  + +M+GD +  D+    RC
Sbjct: 191 PGTGSLAAAVETASGRQALVVGKPSPYMFECITENFSIDPARTLMVGDRLETDILFGHRC 250

Query: 227 GMRALQVRTGKFR 239
           GM  +   TG  R
Sbjct: 251 GMTTVLTLTGVSR 263


>gi|108796653 phosphoglycolate phosphatase [Homo sapiens]
          Length = 321

 Score = 74.7 bits (182), Expect = 8e-14
 Identities = 74/302 (24%), Positives = 125/302 (41%), Gaps = 52/302 (17%)

Query: 8   LAGVRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESQKSRAELVGQ 67
           LA V  +L D  GVL+     G TA+ G+ EA+  L+    ++ F TN S K+RA    +
Sbjct: 25  LADVDTLLFDCDGVLWR----GETAVPGAPEALRALRARGKRLGFITNNSSKTRAAYAEK 80

Query: 68  LQRLGFDI-----SEQEVTAPAPAACQILKER-----GLRPYLLIHDGVRSEFDQIDTSN 117
           L+RLGF       +  EV   A      L++R       + Y+L    + +E + +  ++
Sbjct: 81  LRRLGFGGPAGPGASLEVFGTAYCTALYLRQRLAGAPAPKAYVLGSPALAAELEAVGVAS 140

Query: 118 PNC-----------------------VVIADAGESFSYQNMNNAFQVLMELEKPVLISLG 154
                                      V+      FSY  +  A   L  L++P  + +G
Sbjct: 141 VGVGPEPLQGEGPGDWLHAPLEPDVRAVVVGFDPHFSYMKLTKA---LRYLQQPGCLLVG 197

Query: 155 RG---RYYKETSGLMLDVGPYMKALEYACGIKAEVVGKPSPEFFKSALQAIGVEAHQAVM 211
                R   E    +   G  ++A+E A   +A+++GKPS   F    Q  G+   + VM
Sbjct: 198 TNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVM 257

Query: 212 IGDDIVGDVGGAQRCGMRALQVRTGKFRPSDEHH---------PEVKADGYVDNLAEAVD 262
           +GD +  D+     CG++ +   TG     D  +          ++  D YVD++A+ + 
Sbjct: 258 VGDRLDTDILLGATCGLKTILTLTGVSTLGDVKNNQESDCVSKKKMVPDFYVDSIADLLP 317

Query: 263 LL 264
            L
Sbjct: 318 AL 319


>gi|23308749 N-acetylneuraminic acid phosphatase [Homo sapiens]
          Length = 248

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 14/42 (33%), Positives = 22/42 (52%)

Query: 189 KPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRA 230
           KP+P  F      +GV+    VM+GD +  D+ G    G++A
Sbjct: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKA 205


>gi|37674210 slingshot 2 [Homo sapiens]
          Length = 1423

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)

Query: 42   RLKRSRLKVRFCTNESQKSRAELVGQLQRLGF-DISEQEVTAPAPAACQILKERGLRPYL 100
            R K    +V F    ++ S+      L +LG+ D+ +  +    PA+C+    + L+P+L
Sbjct: 1234 RAKEIESRVVFQAGLTKPSQMRRSASLAKLGYLDLCKDCLPEREPASCESPHLKLLQPFL 1293

Query: 101  LIHDGVRSEFDQIDTSNPNCVVIADAGESFSYQ 133
                G+ +  DQ    NP      +  +SF  Q
Sbjct: 1294 RTDSGMHAMEDQESLENPGAPHNPEPTKSFVEQ 1326


>gi|13654294 haloacid dehalogenase-like hydrolase domain containing
           3 [Homo sapiens]
          Length = 251

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 15/45 (33%), Positives = 23/45 (51%)

Query: 189 KPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQV 233
           KP P  F+ AL+   +E   A  +GD+ + D  G +  GM +  V
Sbjct: 167 KPDPRIFQEALRLAHMEPVVAAHVGDNYLCDYQGPRAVGMHSFLV 211


>gi|96303826 zinc finger protein 16 [Homo sapiens]
          Length = 682

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 127 GESFSYQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLMLDVGPYMKALEYACGIKAEV 186
           G++FSY ++    Q++   EKP   S+  G+ +  +S L+   G +     YAC    + 
Sbjct: 467 GKAFSYSSVLRKHQIIHTGEKPYRCSV-CGKAFSHSSALIQHQGVHTGDKPYACHECGKT 525

Query: 187 VGKPS 191
            G+ S
Sbjct: 526 FGRSS 530


>gi|38045954 zinc finger protein 16 [Homo sapiens]
          Length = 682

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 127 GESFSYQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLMLDVGPYMKALEYACGIKAEV 186
           G++FSY ++    Q++   EKP   S+  G+ +  +S L+   G +     YAC    + 
Sbjct: 467 GKAFSYSSVLRKHQIIHTGEKPYRCSV-CGKAFSHSSALIQHQGVHTGDKPYACHECGKT 525

Query: 187 VGKPS 191
            G+ S
Sbjct: 526 FGRSS 530


>gi|20270253 activating signal cointegrator 1 complex subunit 2
           [Homo sapiens]
          Length = 757

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 8/43 (18%)

Query: 234 RTGKFRPSDEHHPEVKADGYV--------DNLAEAVDLLLQHA 268
           +TGK R S   HPE KAD Y         DN+   V+  L+ A
Sbjct: 17  KTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERA 59


>gi|12056463 coagulation factor VIII-associated protein [Homo
           sapiens]
          Length = 371

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 62/238 (26%), Positives = 91/238 (38%), Gaps = 41/238 (17%)

Query: 25  SGAGGGTA----IAGSVEAVARLKRSRLKVRFCTNESQKSRAELVGQLQRLGFDISEQEV 80
           +G GGG A     AG   A  RL  ++LK RF    +     E  GQ   LG ++  QE 
Sbjct: 6   AGLGGGGAGPGPEAGDFLARYRLVSNKLKKRFLRKPNVAEAGEQFGQ---LGRELRAQE- 61

Query: 81  TAPAPAACQILKER-------GLRPYLLIHDGVRSEFDQIDTSNPNCVVIADAGESF--S 131
             P  A CQ+   R       G    L + +  R    Q   +    V  A  GE    +
Sbjct: 62  CLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLVCPAAYGEPLQAA 121

Query: 132 YQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLMLDVG-PYMKALEYACGIKAEVVGKP 190
              +  A ++ +EL +P            E +  + D+G P   A  +    + ++    
Sbjct: 122 ASALGAAVRLHLELGQPA----AAAALCLELAAALRDLGQPAAAAGHFQRAAQLQL---- 173

Query: 191 SPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRPSDEH--HP 246
            P+   +ALQA+G EA    ++  D  G           AL V T   R + EH  HP
Sbjct: 174 -PQLPLAALQALG-EAASCQLLARDYTG-----------ALAVFTRMQRLAREHGSHP 218


>gi|56090586 coagulation factor VIII-associated (intronic
           transcript) 3 [Homo sapiens]
          Length = 371

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 62/238 (26%), Positives = 91/238 (38%), Gaps = 41/238 (17%)

Query: 25  SGAGGGTA----IAGSVEAVARLKRSRLKVRFCTNESQKSRAELVGQLQRLGFDISEQEV 80
           +G GGG A     AG   A  RL  ++LK RF    +     E  GQ   LG ++  QE 
Sbjct: 6   AGLGGGGAGPGPEAGDFLARYRLVSNKLKKRFLRKPNVAEAGEQFGQ---LGRELRAQE- 61

Query: 81  TAPAPAACQILKER-------GLRPYLLIHDGVRSEFDQIDTSNPNCVVIADAGESF--S 131
             P  A CQ+   R       G    L + +  R    Q   +    V  A  GE    +
Sbjct: 62  CLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLVCPAAYGEPLQAA 121

Query: 132 YQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLMLDVG-PYMKALEYACGIKAEVVGKP 190
              +  A ++ +EL +P            E +  + D+G P   A  +    + ++    
Sbjct: 122 ASALGAAVRLHLELGQPA----AAAALCLELAAALRDLGQPAAAAGHFQRAAQLQL---- 173

Query: 191 SPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRPSDEH--HP 246
            P+   +ALQA+G EA    ++  D  G           AL V T   R + EH  HP
Sbjct: 174 -PQLPLAALQALG-EAASCQLLARDYTG-----------ALAVFTRMQRLAREHGSHP 218


>gi|56090588 coagulation factor VIII-associated (intronic
           transcript) 2 [Homo sapiens]
          Length = 371

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 62/238 (26%), Positives = 91/238 (38%), Gaps = 41/238 (17%)

Query: 25  SGAGGGTA----IAGSVEAVARLKRSRLKVRFCTNESQKSRAELVGQLQRLGFDISEQEV 80
           +G GGG A     AG   A  RL  ++LK RF    +     E  GQ   LG ++  QE 
Sbjct: 6   AGLGGGGAGPGPEAGDFLARYRLVSNKLKKRFLRKPNVAEAGEQFGQ---LGRELRAQE- 61

Query: 81  TAPAPAACQILKER-------GLRPYLLIHDGVRSEFDQIDTSNPNCVVIADAGESF--S 131
             P  A CQ+   R       G    L + +  R    Q   +    V  A  GE    +
Sbjct: 62  CLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLVCPAAYGEPLQAA 121

Query: 132 YQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLMLDVG-PYMKALEYACGIKAEVVGKP 190
              +  A ++ +EL +P            E +  + D+G P   A  +    + ++    
Sbjct: 122 ASALGAAVRLHLELGQPA----AAAALCLELAAALRDLGQPAAAAGHFQRAAQLQL---- 173

Query: 191 SPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRPSDEH--HP 246
            P+   +ALQA+G EA    ++  D  G           AL V T   R + EH  HP
Sbjct: 174 -PQLPLAALQALG-EAASCQLLARDYTG-----------ALAVFTRMQRLAREHGSHP 218


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,608,218
Number of Sequences: 37866
Number of extensions: 402232
Number of successful extensions: 842
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 834
Number of HSP's gapped (non-prelim): 14
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.