Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 33350932
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
(4646 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 9222 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1548 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 1450 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 1427 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 1408 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 1397 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 1384 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1368 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 1365 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 1355 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1344 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1344 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 1308 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 1299 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 1256 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 717 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 539 e-152
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 229 5e-59
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 218 8e-56
gi|31982906 cingulin-like 1 [Homo sapiens] 56 1e-06
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 54 4e-06
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 54 4e-06
gi|21735548 centrosomal protein 2 [Homo sapiens] 54 5e-06
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 54 5e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 54 5e-06
gi|75677376 coiled-coil domain containing 62 isoform b [Homo sap... 52 1e-05
gi|30348972 coiled-coil domain containing 62 isoform a [Homo sap... 52 1e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 51 3e-05
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 50 5e-05
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 50 7e-05
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 9222 bits (23929), Expect = 0.0
Identities = 4646/4646 (100%), Positives = 4646/4646 (100%)
Query: 1 MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKS 60
MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKS
Sbjct: 1 MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKS 60
Query: 61 ALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIK 120
ALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIK
Sbjct: 61 ALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIK 120
Query: 121 RTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAP 180
RTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAP
Sbjct: 121 RTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAP 180
Query: 181 SVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPT 240
SVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPT
Sbjct: 181 SVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPT 240
Query: 241 FLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLT 300
FLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLT
Sbjct: 241 FLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLT 300
Query: 301 LDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAI 360
LDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAI
Sbjct: 301 LDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAI 360
Query: 361 FTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVF 420
FTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVF
Sbjct: 361 FTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVF 420
Query: 421 QTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVI 480
QTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVI
Sbjct: 421 QTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVI 480
Query: 481 VRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSK 540
VRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSK
Sbjct: 481 VRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSK 540
Query: 541 EGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGA 600
EGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGA
Sbjct: 541 EGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGA 600
Query: 601 IREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTA 660
IREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTA
Sbjct: 601 IREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTA 660
Query: 661 YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTI 720
YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTI
Sbjct: 661 YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTI 720
Query: 721 ESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAIS 780
ESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAIS
Sbjct: 721 ESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAIS 780
Query: 781 LIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETV 840
LIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETV
Sbjct: 781 LIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETV 840
Query: 841 FNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWV 900
FNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWV
Sbjct: 841 FNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWV 900
Query: 901 NKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVH 960
NKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVH
Sbjct: 901 NKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVH 960
Query: 961 ELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYR 1020
ELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYR
Sbjct: 961 ELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYR 1020
Query: 1021 NALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQ 1080
NALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQ
Sbjct: 1021 NALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQ 1080
Query: 1081 ALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMT 1140
ALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMT
Sbjct: 1081 ALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMT 1140
Query: 1141 EFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQ 1200
EFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQ
Sbjct: 1141 EFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQ 1200
Query: 1201 RFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTD 1260
RFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTD
Sbjct: 1201 RFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTD 1260
Query: 1261 WEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQ 1320
WEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQ
Sbjct: 1261 WEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQ 1320
Query: 1321 VALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQY 1380
VALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQY
Sbjct: 1321 VALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQY 1380
Query: 1381 ASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQ 1440
ASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQ
Sbjct: 1381 ASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQ 1440
Query: 1441 KNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEH 1500
KNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEH
Sbjct: 1441 KNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEH 1500
Query: 1501 INSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHL 1560
INSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHL
Sbjct: 1501 INSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHL 1560
Query: 1561 LPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLE 1620
LPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLE
Sbjct: 1561 LPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLE 1620
Query: 1621 RERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSRE 1680
RERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSRE
Sbjct: 1621 RERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSRE 1680
Query: 1681 GEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYIT 1740
GEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYIT
Sbjct: 1681 GEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYIT 1740
Query: 1741 WIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQ 1800
WIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQ
Sbjct: 1741 WIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQ 1800
Query: 1801 PPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQ 1860
PPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQ
Sbjct: 1801 PPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQ 1860
Query: 1861 MANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALG 1920
MANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALG
Sbjct: 1861 MANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALG 1920
Query: 1921 HQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQE 1980
HQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQE
Sbjct: 1921 HQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQE 1980
Query: 1981 ALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLA 2040
ALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLA
Sbjct: 1981 ALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLA 2040
Query: 2041 MTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSA 2100
MTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSA
Sbjct: 2041 MTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSA 2100
Query: 2101 GNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSL 2160
GNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSL
Sbjct: 2101 GNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSL 2160
Query: 2161 LSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGL 2220
LSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGL
Sbjct: 2161 LSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGL 2220
Query: 2221 MMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLF 2280
MMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLF
Sbjct: 2221 MMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLF 2280
Query: 2281 THVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVR 2340
THVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVR
Sbjct: 2281 THVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVR 2340
Query: 2341 IMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKG 2400
IMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKG
Sbjct: 2341 IMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKG 2400
Query: 2401 KEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFS 2460
KEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFS
Sbjct: 2401 KEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFS 2460
Query: 2461 MLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRR 2520
MLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRR
Sbjct: 2461 MLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRR 2520
Query: 2521 ITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEAL 2580
ITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEAL
Sbjct: 2521 ITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEAL 2580
Query: 2581 LYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCE 2640
LYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCE
Sbjct: 2581 LYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCE 2640
Query: 2641 YRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTW 2700
YRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTW
Sbjct: 2641 YRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTW 2700
Query: 2701 VKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIP 2760
VKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIP
Sbjct: 2701 VKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIP 2760
Query: 2761 SLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEG 2820
SLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEG
Sbjct: 2761 SLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEG 2820
Query: 2821 LIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKD 2880
LIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKD
Sbjct: 2821 LIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKD 2880
Query: 2881 YIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSG 2940
YIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSG
Sbjct: 2881 YIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSG 2940
Query: 2941 AGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVL 3000
AGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVL
Sbjct: 2941 AGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVL 3000
Query: 3001 DSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIR 3060
DSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIR
Sbjct: 3001 DSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIR 3060
Query: 3061 NLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNY 3120
NLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNY
Sbjct: 3061 NLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNY 3120
Query: 3121 IVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFI 3180
IVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFI
Sbjct: 3121 IVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFI 3180
Query: 3181 NHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKL 3240
NHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKL
Sbjct: 3181 NHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKL 3240
Query: 3241 KKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIK 3300
KKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIK
Sbjct: 3241 KKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIK 3300
Query: 3301 KQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEIS 3360
KQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEIS
Sbjct: 3301 KQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEIS 3360
Query: 3361 DAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLE 3420
DAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLE
Sbjct: 3361 DAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLE 3420
Query: 3421 DDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLK 3480
DDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLK
Sbjct: 3421 DDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLK 3480
Query: 3481 SLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQAN 3540
SLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQAN
Sbjct: 3481 SLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQAN 3540
Query: 3541 IQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFI 3600
IQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFI
Sbjct: 3541 IQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFI 3600
Query: 3601 MNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRV 3660
MNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRV
Sbjct: 3601 MNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRV 3660
Query: 3661 LITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAE 3720
LITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAE
Sbjct: 3661 LITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAE 3720
Query: 3721 RPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEV 3780
RPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEV
Sbjct: 3721 RPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEV 3780
Query: 3781 TRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVL 3840
TRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVL
Sbjct: 3781 TRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVL 3840
Query: 3841 YENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPT 3900
YENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPT
Sbjct: 3841 YENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPT 3900
Query: 3901 YDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIW 3960
YDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIW
Sbjct: 3901 YDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIW 3960
Query: 3961 LDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSI 4020
LDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSI
Sbjct: 3961 LDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSI 4020
Query: 4021 MEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQA 4080
MEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQA
Sbjct: 4021 MEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQA 4080
Query: 4081 DKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLR 4140
DKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLR
Sbjct: 4081 DKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLR 4140
Query: 4141 AGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLG 4200
AGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLG
Sbjct: 4141 AGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLG 4200
Query: 4201 WSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEF 4260
WSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEF
Sbjct: 4201 WSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEF 4260
Query: 4261 DQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSW 4320
DQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSW
Sbjct: 4261 DQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSW 4320
Query: 4321 LGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTL 4380
LGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTL
Sbjct: 4321 LGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTL 4380
Query: 4381 HTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEG 4440
HTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEG
Sbjct: 4381 HTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEG 4440
Query: 4441 KKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGG 4500
KKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGG
Sbjct: 4441 KKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGG 4500
Query: 4501 AKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGV 4560
AKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGV
Sbjct: 4501 AKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGV 4560
Query: 4561 TGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIF 4620
TGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIF
Sbjct: 4561 TGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIF 4620
Query: 4621 TVDFEIATKEDPRSFYERGVAVLCTE 4646
TVDFEIATKEDPRSFYERGVAVLCTE
Sbjct: 4621 TVDFEIATKEDPRSFYERGVAVLCTE 4646
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 1548 bits (4009), Expect = 0.0
Identities = 1229/4466 (27%), Positives = 2130/4466 (47%), Gaps = 483/4466 (10%)
Query: 304 LKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATEL-DKIRQALVAIFT 362
++ R + +S + K+ ET+ ++F D LS E+ D + +
Sbjct: 180 IEQAHRGNKQISKERANYFKELFETI------AREFYNLDSLSLLEVVDLVETTQDVVDD 233
Query: 363 HLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQT 422
R+ + YP R L L++ I + K LGT L Y ++ + A + +
Sbjct: 234 VWRQTEHDHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQ 293
Query: 423 WDDEYEKL--QVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVI 480
W L QV R + + E KL RL+++ R HE+
Sbjct: 294 WVIVCNHLTGQVWQRYVPHPWKNEKY-----FPETLDKLGKRLEEVLAIRTIHEKF---- 344
Query: 481 VRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSK 540
+ F A I + +E ++ + +
Sbjct: 345 -----------------------------LYFLPASEEKIICLTRVFEPFTGLNPVQYNP 375
Query: 541 EGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNA-NEMFRIFSRFNALFVRPHIRG 599
W+AA+ +Y++ I E +I +L++ + +++ ++ + F ++ L RP I
Sbjct: 376 YTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDSPQQLLQAFLKYKELVKRPTISK 435
Query: 600 AIREYQTQLIQRVKDDIESLHDKFKVQ---YPQSQACKMSHVRDLPPVSGSIIWAKQIDR 656
+ + L+ R+ D I+ F+ + P + +S ++L V SI+W +Q++
Sbjct: 436 ELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSG-KNLSEVVNSIVWVRQLEL 494
Query: 657 QLTAYMKRVEDVLGK--GWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVS 714
++ +K E +L G+ + K D ++KL QE FDDW+R +Q
Sbjct: 495 KVDDTIKIAEALLSDLPGFRCFHQSAKDLLD----QLKLYEQEQFDDWSRDIQSGLSDSR 550
Query: 715 GRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQL 774
+ S+R+ N LKV++ ++ L +EVR L LGF +P I A+ A +
Sbjct: 551 SGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANIAQKF 610
Query: 775 YPFAISLIESVRTYERTCEKVEERNTISLLVAGLK-----KEVQALIAEGIALVWESYK- 828
AI L + Y +++ + +L + L K +A + W++ K
Sbjct: 611 CKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKE 670
Query: 829 LDPYVQRL---AETVFNFQEKVD-------DLLIIEEKIDLEVRSLETCMYDHKTFSEIL 878
L+ Y+Q+L AE + K+ + +++ IDL + + + + L
Sbjct: 671 LEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNIDL--------LRQQQRWKDGL 722
Query: 879 NRVQKAVDDLNLHSY--SNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEV 936
++ + + + S++ W + ++ + L + Q GL A E+ E+
Sbjct: 723 QELRTGLATVEAQGFQASDMHAWKQHWNHQLYKALEHQYQMGLEALN-------ENLPEI 775
Query: 937 DMDTDAPQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSL 996
++D +++K G + PP EE R K Y+EM + + +
Sbjct: 776 NID-----LTYKQGR-----------------LQFRPPFEEIRAKYYREMKRF----IGI 809
Query: 997 PRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQ 1056
P + G +E + + R G + + + +S V K W+
Sbjct: 810 PNQFKGVGEAG-------DESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWI- 861
Query: 1057 YQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKV 1116
+ + E + + ++ W+ ++ + + + + I+ V++ +
Sbjct: 862 --VIGQVDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVI 919
Query: 1117 NLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSL 1176
+ ++ + + +++ E + ++++ + L DA + +Q
Sbjct: 920 DDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQER 979
Query: 1177 KRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQV 1236
K +I ++ E + RLL R I N++ +W F +M I+ Q+
Sbjct: 980 KPEILPLFQEAE---DKNRLL---RTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQI 1033
Query: 1237 ANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREK 1296
++ V+SR + EK K L+P + + I G+ L D K
Sbjct: 1034 EVMKGN-------VKSRLQIYYQELEKFKARWDQLKPGDDV----IETGQHNTL-DKSAK 1081
Query: 1297 CAKAKEA----LELTDTGLLSG------SEERVQVALEELQDLKG---VWSELSKVWEQI 1343
K K+ LE+T L+ E +A +D++ +W+ + +
Sbjct: 1082 LIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGF 1141
Query: 1344 DQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIEL 1403
+M + W++ R L ++ RLR+ + + L+ + +VI +
Sbjct: 1142 QEMANEDWIT-----FRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPI 1196
Query: 1404 ----KSEALKDRHWKQLMKRLHV--NWVVSELTLGQIWDV--DLQKNEAIVKDVLLVAQG 1455
+ E L HW L + L + + +L G + V + A +KD+ AQG
Sbjct: 1197 LKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQG 1256
Query: 1456 EMALEEFLKQIREVWNTYEL-DLVNYQNK----CRLIRGWDDLFNKVKEHINSVSAMKLS 1510
E+ + E L+++ ++W + L++Y++ +LI+ W D+ N+V ++ + ++K S
Sbjct: 1257 EVTIREALREL-DLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDS 1315
Query: 1511 PYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQS 1570
PYYK FE+ WE KL + +QR+WVYLE IF A LP E RF
Sbjct: 1316 PYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRGA-----LPKEQTRFNR 1370
Query: 1571 ISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFY 1630
+ +F ++M + K V + G++ SL + D L + QK+L E+LE +RS+FPRFY
Sbjct: 1371 VDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFY 1430
Query: 1631 FVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPV 1690
F+GD+DLLEI+G S N + +Q H KK+FAG++S+ +E + + + S EGE V FK V
Sbjct: 1431 FIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKV 1490
Query: 1691 SITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKAT--SIDPNTYITWIDKYQAQ 1748
++ + + WL + EM+ TL +LL E VT G+++ ++DP+ + +Q
Sbjct: 1491 PLSNN--VETWLNDLALEMKKTLEQLLKECVTT----GRSSQGAVDPSLF-------PSQ 1537
Query: 1749 LVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPP------ 1802
++ L+ QI ++E+VE A+ LH + + + L + + P
Sbjct: 1538 ILCLAEQIKFTEDVENAIKDHS-------LHQIETQLVNKLEQYTNIDTSSEDPGNTESG 1590
Query: 1803 LRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMA 1862
+ KL+ LI +++H DV + L + ++ + + W Q+RFY T +QM
Sbjct: 1591 ILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSDHT-----CCVQMV 1645
Query: 1863 NAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQ 1922
+++F Y +EY G KLV TPLTD+CYLT+TQA++ LGG+P+GPAGTGKTESVKALG
Sbjct: 1646 DSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGL 1705
Query: 1923 LGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEAL 1982
LGR VLVFNCDE D ++MGRIFVGL + GAWGCFDEFNRLEE +LSAVS Q+Q IQ+AL
Sbjct: 1706 LGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDAL 1765
Query: 1983 REHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNP---GYAGRSNLPDNLKKLFRSL 2039
+ H CELL K+V+V+ + IFITMNP GY GR LPDNLK+LFR +
Sbjct: 1766 KNHRT----------VCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPV 1815
Query: 2040 AMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVS 2099
AM+ PD +LIA+V+LYS+GF+ A+VL+ K+V F L E L+ Q HYD+GLRALK+VL
Sbjct: 1816 AMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRG 1875
Query: 2100 AGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFS 2159
+GN+ R+ +++ +N E I++Q++ + K D +
Sbjct: 1876 SGNLLRQ---------------LNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDA 1920
Query: 2160 LLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHG 2219
L+ DVFPG++ E L LK+V +E E+ ++K L+LY+ G
Sbjct: 1921 LIKDVFPGIELKEVEYDELSAALKQVFEEA------NYEIIPNQIKKALELYEQLCQRMG 1974
Query: 2220 LMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGL 2279
+++VGPSG+GKS WR+L AL + G + ++PKA+ + L G +D +TREW+DG+
Sbjct: 1975 VVIVGPSGAGKSTLWRMLRAALCKT-GKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGV 2033
Query: 2280 FTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNV 2339
T+ R++ VR WI+ DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV
Sbjct: 2034 LTNSARQV---VREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNV 2090
Query: 2340 RIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRK 2399
+FE DL A+ AT+SR GM++ S++ + + ++L R+ P A+ R
Sbjct: 2091 NFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWL---RNQP-------AEYRNN 2140
Query: 2400 GKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAF-QLEHIMDLTRLRCLGSL 2458
+ G+ YF KAL+ Q +++++ + + + +
Sbjct: 2141 LENWIGD-------------------YFE------KALQWVLKQNDYVVETSLVGTVMNG 2175
Query: 2459 FSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYI 2518
S LH CR+ ++ N L+ + +L+ SRL+ E+ +
Sbjct: 2176 LSHLH-GCRDHDEFIIN------------------LIRGLGGNLNMKSRLEFTKEVFHWA 2216
Query: 2519 RRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQ-IEVETHKVAAPDVVVPTLDTVRH 2577
R P + P+ Y S G + + K P+ + + V+ T D R
Sbjct: 2217 RES-----PPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRG 2271
Query: 2578 EALLYTWLAEH--KPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTF 2635
WL+ +P +L GP G GK M L A L ++ ++ S+ TT LL+
Sbjct: 2272 LDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKL 2331
Query: 2636 DHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRT 2695
C T G V P + LVL+ +INLP +DK+GT +++F++Q++ + GFY
Sbjct: 2332 SQTCMVISTNTGRVYRPKDCER-LVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFY-D 2389
Query: 2696 SDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAM 2755
+ WV LE IQ V + + GR L+ RF V + +DYP L IYG + +
Sbjct: 2390 ENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPV 2449
Query: 2756 LRLIPSLRTYA--------EPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIF 2807
L +L+ ++ L +MV+ Y + +FT D HY ++P +T+WV G+F
Sbjct: 2450 LH--KNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLF 2507
Query: 2808 --EALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERR-------------WTDENIDT 2852
+ P++ ++ I A+EA RLF+D++V +E W + +D
Sbjct: 2508 RYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDN 2567
Query: 2853 VALKHFP------NIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELD 2906
++ + N A +P+ K ++ +L+D +K L + + +
Sbjct: 2568 MSDSFYVTWGARHNSGARAAPGQPLPPHG---KPLGKLNSTDLKDVIKKGLIHYGRDNQN 2624
Query: 2907 VPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRK 2966
+ ++LF+EVL+++ RIDR+ P G LLL G SG G+ T++ V+ M+G ++ K+ R
Sbjct: 2625 LDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRG 2684
Query: 2967 YTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEY 3026
Y + F DL+ VL+ +G + +++ ++++ + FLE +N+LL++GEVPGL+ +E
Sbjct: 2685 YELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEEL 2744
Query: 3027 ATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALF 3086
L+ K+ A ++G ++ +FT ++ +NLH+V M+ ++ ++PAL
Sbjct: 2745 EPLLLPLKDQASQDGFF----GPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALH 2800
Query: 3087 NRCVLNWFGDWSTEALYQV----------GKEFTSKMDLE--KPNYIVPDYMPVVYDKLP 3134
+C + W WS ++ ++ G+++ K E K N + PD++
Sbjct: 2801 KKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFL-------- 2852
Query: 3135 QPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSEL 3194
S + +H++ A TP Y+ F++ Y+ + K+ EL
Sbjct: 2853 ----------KSFLLIHESCKAYGA------------TPSRYMTFLHVYSAISSSKKKEL 2890
Query: 3195 EEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKK 3254
++Q HL G+ K+ E V+EL R +S L+ K A+ L+ + Q+A ++K
Sbjct: 2891 LKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQK 2950
Query: 3255 VMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPP 3314
+ ++ ++ ++ I +++ + ++L +V+P V EA+ AV +IK + L E+RS+ PP
Sbjct: 2951 TELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPP 3010
Query: 3315 AAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSN 3374
++ LE + L+G T W ++S + + I F A IS IRE +++ N
Sbjct: 3011 DVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKN 3070
Query: 3375 P-SYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEV 3433
S++ + RAS A P+ W A + Y+ +L+R+ PL E LE + K + + ++
Sbjct: 3071 KGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKL 3130
Query: 3434 EQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTS 3493
E+++ + ++ KE++ SEA ++A+++ + + + L+ L E +RW
Sbjct: 3131 EELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQV 3190
Query: 3494 ETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYL 3553
+++T+ L+AAFI Y + +R+ W+ + A ++ + D+ R +L
Sbjct: 3191 VEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWT---KSAGLE-KFDLRR--FL 3244
Query: 3554 SNADERLRWQASSLPADDLCTENAIM------LKRFNRY-PLIIDPSGQATEFIMNEYKD 3606
E+L W++ LP+DDL ENA++ LK ++R P +IDPS QATE++ KD
Sbjct: 3245 CTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKD 3304
Query: 3607 RKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGD 3666
++ + D F LE A+RFG L++Q+++ +PVL P+L R++ G R ++ +GD
Sbjct: 3305 SRLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGD 3364
Query: 3667 QDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDE 3726
+ ID + F +FLSTR+P PPD S VT VNFT TRS L+ Q L ++ E+PD++E
Sbjct: 3365 KIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEE 3424
Query: 3727 KRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEE 3786
+++ LL+ + + +++L +LE+SLL+ L +G IL++ +I +L K +A + ++E
Sbjct: 3425 QKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKE 3484
Query: 3787 TDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNL 3846
+ + ++ YLPL+ + S +YF + L +I+ +Y++SL FL ++ L N
Sbjct: 3485 SYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRAL---QNK 3541
Query: 3847 KGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQ 3906
+ + QR+ + L + + + R + D + FA+ R E +D F
Sbjct: 3542 QDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDT-FT 3600
Query: 3907 HFLRGNEIVLSAGSTPRIQG-----LTVEQAEAVVRLS-CLPAFKDLIAKVQADEQFGIW 3960
+ G +++ A S +I+ + E++ AV L LP+ + A + +
Sbjct: 3601 GVVVG-DMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDA-ALWRTY 3658
Query: 3961 LDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSI 4020
++S EQ P + +++ ++L++QA RPDRL + +F LG +
Sbjct: 3659 YNNSMCEQEFPSILAKKV------SLFQQILVVQALRPDRLQSAMALFACKTLG--LKEV 3710
Query: 4021 MEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQA 4080
PL+L + E P+L+ PG D S +++LA + + + +G QA
Sbjct: 3711 SPLPLNLKRLY-KETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQG--QA 3767
Query: 4081 DKAI---NTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVN 4137
D AI ++G W+ LKN+HL WL LEK+L++LQP FRL+LT E++P
Sbjct: 3768 DLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVHPNFTPI 3827
Query: 4138 LLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPN-ERARLYFLLAWFHAIIQERLRY 4196
LL++ +E PPG+K N++RT+ S +I K N RA F LAWFHA QER Y
Sbjct: 3828 LLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNY 3887
Query: 4197 APLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRV 4256
P GW+K YEF SDLR+ + +D L D AK + W + L+ +IYGGR+
Sbjct: 3888 IPQGWTKFYEFSLSDLRAGYNIIDR-LFDGAK--------DVQWEFVHGLLENAIYGGRI 3938
Query: 4257 DNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQ 4316
DN FD R+L ++L++ F + D + K + +P ++ +E +P+
Sbjct: 3939 DNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDD 3998
Query: 4317 TPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAW 4376
PS+ GLP N R +M+ Q++ L ++ T + R W
Sbjct: 3999 KPSFFGLPANIAR---------SSQRMISSQVISQLRILG------RSITAGSKFDREIW 4043
Query: 4377 MRTLHTTASNWLHLIPQT-LSHLKRTVENIK--DPLFRFFEREVKMGAKLLQDVRQDLAD 4433
L + W L + L H K N + P+ F E +L+Q V Q LA
Sbjct: 4044 SNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAA 4103
Query: 4434 VVQVCEGKKKQTNYLRTLINELVKGILPRSW-SHYTVPAGMTVIQWVSDFSERIKQLQNI 4492
+ +V G ++ ++ L + L+ P +W S + P +Q++ R +QN
Sbjct: 4104 LSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPE--DPLQYLRGLVARALAIQNW 4161
Query: 4493 SLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGAT 4552
A + L + + L LF P+ ++ A RQ A+A S++ L V + +G
Sbjct: 4162 VDKAEK---QALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKF---VASWKGRL 4215
Query: 4553 LDA-CSFGVTGLKLQGATCNNNKLSL----SNAISTALPLTQLRWVKQ--TNTEKKASVV 4605
+A ++GL L+G + + N+LS S ++S+ LP + W+ Q +
Sbjct: 4216 QEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCF-MGWIPQDACGPYSPDECI 4274
Query: 4606 TLPVYLNFTRADLIFTVDFEIATKED 4631
+LPVY + R ++ +D +D
Sbjct: 4275 SLPVYTSAERDRVVTNIDVPCGGNQD 4300
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 1450 bits (3753), Expect = 0.0
Identities = 1104/4136 (26%), Positives = 1980/4136 (47%), Gaps = 406/4136 (9%)
Query: 642 PPVSGSIIWAKQIDRQLTAYMKR---VEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEI 698
PPV+G+I W + + ++ + R V+++L V+ QK + G + MK
Sbjct: 566 PPVAGAIYWERSLFFRIKHTILRFQEVQEILDSDRGQEVK-QKYLEVGRT--MKEYEDRK 622
Query: 699 FDDWARKVQQ-------RNLGVSGRIFTIE-STRVRGRTGNVLKLKVNFLPEIITLSKEV 750
++ W +Q ++L I T E ST RG +NF P + + E
Sbjct: 623 YEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGAV-----FAINFSPALREIINET 677
Query: 751 RNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKK 810
+ L+ LGF VP N A Q ++ + + + Y + + S+L+ +
Sbjct: 678 KYLEQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIGTLNDAE--SVLLKDHSQ 735
Query: 811 EVQALIAEGIA-LVWESYKLDPYVQRLAETVFNFQEKV-------DDL---LIIEEKIDL 859
E+ + G L W S + Y+ + + F+ V DD+ L + E I+L
Sbjct: 736 ELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINL 795
Query: 860 --------------------EVRSLETCMYDHKT-----FSEILNRVQKAVDDLNLHSYS 894
+ DH +L +V+ V N
Sbjct: 796 FKYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNTGKAP 855
Query: 895 NLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPK 954
L + + +I +L + L+++ ++LG + AP++ P
Sbjct: 856 KLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNVP-LFHTETILTAPEIILHPNTNEI 914
Query: 955 IKNVVHELR----ITNQVI-YLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVH 1009
K H +R IT + ++N EC P + +
Sbjct: 915 DKMCFHCVRNCVEITKHFVRWMNGSCIEC------------------PPQKGE------- 949
Query: 1010 YELTEEEKFYRNALTRMPDGPVALEESYSA---VMGIVSEVEQYVKVWLQYQCLWDMQAE 1066
EEE N + P +E++ V I+ + +Y++ W +Y+ LW +
Sbjct: 950 ----EEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKA 1005
Query: 1067 NIYNRLG----------EDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKV 1116
+ + E L + + ++ + K+ + + + + V
Sbjct: 1006 IVMEKFAAKKPPCVAYDEKLQFYSKIAYEVMRH-------PLIKDEHCIRLQLRHLANTV 1058
Query: 1117 NLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSL 1176
SW + G++L + E ++ +E+E + + + + + +V +
Sbjct: 1059 QENAKSW----VISLGKLLNESAKE---ELYNLHEEMEHLAKNLRKIPNTLEDLKFVLAT 1111
Query: 1177 KRKIKQFEKQVEL-YRNGQRLLEKQRFQ--FPPSWL--YIDNIEGEWG-----------A 1220
+I+ +EL YR+ Q FPP +D IE W A
Sbjct: 1112 IAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHA 1171
Query: 1221 FNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQAL 1280
DI R + ++ N +++I + + S + D ++ ++ L
Sbjct: 1172 LGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEGPGSVGD-----------DLDKGVELL 1220
Query: 1281 TIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVW 1340
+YE + R + R++ A A++ +L T + +VQ + L+ + ++ L
Sbjct: 1221 GVYERELARHEKSRQELANAEKLFDLPIT--MYPELLKVQKEMSGLRMIYELYEGLKVAK 1278
Query: 1341 EQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLV 1400
E+ Q W+++ + L++ ++ L L+ P +R + +++ +K + L+
Sbjct: 1279 EEWSQTL---WINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKAFKDSIPLL 1335
Query: 1401 IELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIWDVDLQKNEAIVKDVLLVAQGEMAL 1459
++LK+EAL+DRHWK+LM++ V + ++E TL ++ ++L K+ ++ +++ A E+A+
Sbjct: 1336 LDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAI 1395
Query: 1460 EEFLKQIREVWNTYELDLVNY----QNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKV 1515
E+ +K+I + W + +V Y Q + ++ D++ + ++ ++ ++ S +
Sbjct: 1396 EKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGP 1455
Query: 1516 FEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEF 1575
F + WE L+ I + ++W+ VQR+W+YLE IF G DI+ LP E ++F +I F
Sbjct: 1456 FLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGG-DIRSQLPEEAKKFDNIDKVF 1514
Query: 1576 LALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDE 1635
+M + K P++ L+ +++ L K QK+L +YL+ +R++FPRF+F+ D+
Sbjct: 1515 KRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDD 1574
Query: 1636 DLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS---VVLGISSREGEEVMFKTPVSI 1692
+LL I+G+S + +Q+H KM+ ++S+ N+ +S +V + S EGE + F+ +
Sbjct: 1575 ELLSILGSSDPLC-VQEHMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRK--IL 1631
Query: 1693 TEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVL 1752
++ +W+T V EMR T + E++ + + + W+ YQ +V+
Sbjct: 1632 RAEGRVEDWMTAVLNEMRRTNRLITKEAIFRY--------CEDRSRVDWMLLYQGMVVLA 1683
Query: 1753 SAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLI 1812
++Q+ W+ VE G A + + + ++ L + M R+K ++
Sbjct: 1684 ASQVWWTWEVEDVFHKAQKGEKQA-MKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVL 1742
Query: 1813 TELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEY 1872
VH RD+ S I+ I A+ F+W SQ+RFY+D + +L+I+ F YG+EY
Sbjct: 1743 IIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREP----DELNIRQCTGTFGYGYEY 1798
Query: 1873 LGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNC 1932
+G+ +LV TPLTDR YLT+TQAL LGG+P GPAGTGKTE+ K L LG +V NC
Sbjct: 1799 MGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNC 1858
Query: 1933 DETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDK 1992
E D++A+G+IF GL Q GAWGCFDEFNR++ +LS +S Q+Q I+ AL
Sbjct: 1859 GEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLT----- 1913
Query: 1993 TSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQV 2052
T + +++ + M IFITMNPGYAGR+ LP+++K LFR + + PD Q I ++
Sbjct: 1914 -----TFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEI 1968
Query: 2053 MLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIK 2112
ML+S+GF A+ LA K+ +KL EQLS Q HYDFGLRALKSVLV AG +KR
Sbjct: 1969 MLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRG------ 2022
Query: 2113 REKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHR 2172
+ +L E +L++++ + +PK V ED+PL L+SD+FPG+ R
Sbjct: 2023 ---------------SSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPR 2067
Query: 2173 GEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSM 2232
+ +++V +E +G V + V+KV+Q+++ H M+VGP+ GKS+
Sbjct: 2068 VRYPDFNDAVEQVLEE------NGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSV 2121
Query: 2233 AWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVR 2292
L +A +L G+ +I++PKA+S LYG LDP TR+WTDG+ +++ R+I
Sbjct: 2122 VINTLCQAQTKL-GLTTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPT- 2179
Query: 2293 GELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYAT 2352
+ ++R++I+FDGDVD WVEN+NSV+DDN+LLTL NGER+ L + ++FEV DL+YA+
Sbjct: 2180 -DKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYAS 2238
Query: 2353 LATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPM 2412
ATVSRCGMV+ L + ++ ++ P
Sbjct: 2239 PATVSRCGMVYVDPKNLKYRPYWKKWVNQI----------------------------PN 2270
Query: 2413 LQIQRDAATIMQPY--FTSNGLVTKALE--HAFQLEHIMDLTRLRCLGSLFSMLHQACRN 2468
Q + ++ + Y + + +V ++ A +L+ I+ T L + L ML
Sbjct: 2271 KVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEG 2330
Query: 2469 VAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPT 2528
+ ++ LE Y L ++ SL D R+K EYI+R+ ++
Sbjct: 2331 EIE----------DLDLLECYFLEALYCSLGASLLEDGRMKF----DEYIKRLASLSTVD 2376
Query: 2529 APNI------------PIIDYEVSIS-GEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTV 2575
+ + D+ +W PW VP+ + + +++V T+DT
Sbjct: 2377 TEGVWANPGELPGQLPTLYDFHFDNKRNQWVPWSKLVPEY-IHAPERKFINILVHTVDTT 2435
Query: 2576 RHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDME--VVGLNFSSATTPELLLK 2633
R +L + +P++ G G+ KT T + L+ L + V+ +NFSS TT + +
Sbjct: 2436 RTTWILEQMVKIKQPVIFVGESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQR 2495
Query: 2634 TFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY 2693
+ E +RT + P +GK L++F D++N+P +D+YGTQ+ I+ ++ ++E G Y
Sbjct: 2496 NLEANVE-KRTKD--TYGP-PMGKRLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLY 2551
Query: 2694 -RTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFN 2752
R + + + F+ A GR + RF+ V V +P SL IY +
Sbjct: 2552 DRGKELNCKSIRDLGFIAAMGK-AGGGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSIL 2610
Query: 2753 RAMLRLIPSLRTYAEPLTAAM--VEFYTMS-QERFTQDTQP-----HYIYSPREMTRWVR 2804
+ T+ E + A + F T++ + QD P HYI++ R+++R
Sbjct: 2611 KG------HTSTFHESIVAVSGKLTFCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFN 2664
Query: 2805 GIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDRE 2864
G+ P V ++R+W +E LR+F DRL+ + +++ ++I ++ ++HF + D E
Sbjct: 2665 GLV-LTNPERFQTVAQMVRVWRNECLRVFHDRLISETDKQLVQQHIGSLVVEHFKD-DVE 2722
Query: 2865 KAMSRPILYSNWLSK--DYIPVDQEELRDYVKAR------LKVFYEEELDVPLVLFNEVL 2916
M PIL+ ++ + P E+++DY A+ L+ + E + LVLF++ L
Sbjct: 2723 VVMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQEILEEYNESNTKMNLVLFDDAL 2782
Query: 2917 DHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDL 2976
+H+ R+ RI R +GH LL+GV G+GK +LSR A+ V++I + R Y+ F EDL
Sbjct: 2783 EHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDL 2842
Query: 2977 RTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEG 3036
+++ + G +N+ + F+ +++V + GFLE +N +L +G VP LF +E ++++Q +
Sbjct: 2843 KSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQE 2902
Query: 3037 AQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGD 3096
A K+G M + E ++++F ++ NLH+V M+P + L+ P + N ++WF
Sbjct: 2903 ALKQG-MGPAKESVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMP 2961
Query: 3097 WSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQ 3156
W +AL+ V K F Y P++ P + E +V V VHQ++
Sbjct: 2962 WPPQALHAVAKSFLG-------------YNPMI------PAENIENVVKHVVLVHQSVDH 3002
Query: 3157 ANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVE 3216
+ + ++ R+ +TP++YLDFIN Y+ L EK Q L+ GL K+KE Q++
Sbjct: 3003 YSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLD 3062
Query: 3217 ELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQM 3276
EL + L + L K+AA L+++ + AE+KK +++E ++ +Q +VIA ++
Sbjct: 3063 ELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKA 3122
Query: 3277 SVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWK 3336
+ L +V P + A+ ++ + K + E+RS A PP V+ E I ++ G +WK
Sbjct: 3123 EAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWK 3182
Query: 3337 QIRSIIMRENFIPTIVNFSAEEISDAIREKMKK--NYMSNPSYNYEIVNRASLACGPMVK 3394
+ ++ NF+ +++ + I+ + + +K ++ + E V++A L M+K
Sbjct: 3183 TAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLG---MLK 3239
Query: 3395 WAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVL 3454
+ A + Y D+ + ++P R ++ +LE + +++ ++ + ++ + +Y
Sbjct: 3240 FVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAA 3299
Query: 3455 ISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFI 3514
I E Q ++ + +E ++ + L+ L +E RW + ++ + GDCLL AAF+
Sbjct: 3300 ILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFL 3359
Query: 3515 AYAGYFDQQMRQNLFTT-WSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLC 3573
+Y G F + R + W + + + I L++ E RW + LP D+L
Sbjct: 3360 SYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELS 3419
Query: 3574 TENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPL 3633
+N I+ R +R+PL IDP QA +I + + + SF D F K LE ++++G P
Sbjct: 3420 VQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPF 3479
Query: 3634 LVQDVESY-DPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDL 3692
L +DV+ Y DPV++ VL + ++ + GR I LGD+++D +F ++L+T+ + P +
Sbjct: 3480 LFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSV 3539
Query: 3693 CSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQA 3752
+ +N+TVT L+ Q L+ ++ ER +++E+R L++ E + L+ LE SLL+
Sbjct: 3540 FGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRE 3599
Query: 3753 LNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIY 3812
L G +LD+ ++ TLE K +A EV+ K++ + +++ + Y P + + ++
Sbjct: 3600 LATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILF 3659
Query: 3813 FTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDH--TQRLSIITKDLFQVAFNR 3870
F + + ++ +YQYSL FL+++ L K + D +RL I L +N
Sbjct: 3660 FVLSEMALVNSMYQYSLIAFLEVFRLSL-----KKSLPDSILMKRLRNIMDTLTFSIYNH 3714
Query: 3871 VARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVE 3930
G+ + + F+ + IK++ G + E FL+GN + + L+ +
Sbjct: 3715 GCTGLFERHKLLFSFNMT-IKIEQAEGRVPQE-ELDFFLKGNISLEKSKRKKPCAWLSDQ 3772
Query: 3931 QAEAVVRLSCLPAFKDLIAKVQADEQ-----FGIWLDSSSPEQTVPYLWSEETPATPIGQ 3985
E ++ LS F D ++ D + + W D S EQ P + TP
Sbjct: 3773 GWEDIILLS--EMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQ-FPVPLGYDNNITP--- 3826
Query: 3986 AIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCS 4045
+LL+++ FR DR+ +V+ +GE + ++ P+ + + P++P++
Sbjct: 3827 -FQKLLILRCFRVDRVYRAVTDYVTVTMGEKY---VQPPMISFEAIFEQSTPHSPIVFIL 3882
Query: 4046 VPGYDASGHVEDLAAEQ---NTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLA 4102
PG D + + LA ++ +A+G + A + + TAV G+W+ML+N HL
Sbjct: 3883 SPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQE-KVALQLLETAVARGQWLMLQNCHLL 3941
Query: 4103 PGWLMQLEKKLHSL-QPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTF 4161
WL LEK L + +PH FRL+LT + P+ +L+ V EPP G+K NM T+
Sbjct: 3942 VKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATY 4001
Query: 4162 SSIPVSRICKSPNERAR-LYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVD 4220
I + + P+ + L ++LA+FHA++QER ++ +GW+ Y+F ESD + + ++
Sbjct: 4002 FKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILN 4061
Query: 4221 TWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDS 4280
T+L K Q P +IPW +LK L+ + +YGGR + FD+R+L +++ FD+
Sbjct: 4062 TYL---TKAFQQRDP-RIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDT 4117
Query: 4281 EFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMI 4340
+ D ++P G +E+FV+ +E LP TP GL NAE T DM
Sbjct: 4118 FQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMW 4177
Query: 4341 SKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKR 4400
+ +L++Q +T S+ R ++ + N + + L +++
Sbjct: 4178 AHLLELQ--------------PQTGESSSGISRDDYIGQVAKEIENKMPKV-FDLDQVRK 4222
Query: 4401 TVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGIL 4460
+ P +E++ KL+ + + LA++ + G+ +N L + L G +
Sbjct: 4223 RLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHI 4282
Query: 4461 PRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAY 4520
P W ++ W+ F R Q E + + L GL +PE+Y
Sbjct: 4283 PNIWRRLAPDTLKSLGNWMVYFLRRFSQYML--------WVTESEPSVMWLSGLHIPESY 4334
Query: 4521 ITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFG----VTGLKLQGATCNNNK-- 4574
+TA Q + N W L+ L VT Q A G V+GL L+GA + K
Sbjct: 4335 LTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGC 4394
Query: 4575 --LSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRAD-----LIFTVD 4623
S + LP+ ++ + + + K + PVY R + L+F D
Sbjct: 4395 LIKSKPKVLVVDLPILKIIPI-EAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEAD 4449
Score = 36.6 bits (83), Expect = 0.60
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
Query: 231 DFGDKVEDPTFLNQLQSGVNRWIREIQKVTK--LDRDPASGTALQEISFWLNLERALYRI 288
+ D DP ++ L+ V W+ +I + L + P L EI FW L +
Sbjct: 234 EVSDLAADPETVDILEQCVINWLNQISTAVEAQLKKTPQGKGPLAEIEFWRERNATLSAL 293
Query: 289 QEKRESPEVLLTLDILK 305
E+ + P V LD++K
Sbjct: 294 HEQTKLPIVRKVLDVIK 310
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 1427 bits (3693), Expect = 0.0
Identities = 1065/4006 (26%), Positives = 1906/4006 (47%), Gaps = 309/4006 (7%)
Query: 735 LKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTC-- 792
L VNF ++ L E+ + L F P +VN A +A L +L+ R Y R
Sbjct: 629 LDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILRENLLLVARDYNRIIAM 688
Query: 793 ----EKVEERNTISLLVA----GLKKEVQALIAEGIALVWE----SYKLDPYVQRLAETV 840
E+ + I LL GLKK AL + E + K+ V +
Sbjct: 689 LSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRIHASKVQMIVNEFKAST 748
Query: 841 FNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDD--LNLHSYSNLPI 898
+ ++ EK L VR +Y F E + AV +NLH + I
Sbjct: 749 LTIGWRAQEM---SEK--LLVRISGKRVYRDLEFEEDQREHRAAVQQKLMNLHQ-DVVTI 802
Query: 899 WVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKN- 957
N E+ + G +Q + L ED +++ ++S G+ K
Sbjct: 803 MTNSY--EVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGKTSPN 860
Query: 958 --------VVHELRITNQVIYLNPPIEECR---YKLYQEMFAWKMVVLSLPRIQSQRYQV 1006
+ ++L+ + + +P ++ + +F+ V LP I ++R
Sbjct: 861 PLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTKRK-- 918
Query: 1007 GVHYE----LTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWD 1062
+H E + E+++ + T++ G + S ++ Y+K W Y+ +W+
Sbjct: 919 -LHREPIQTVVEQDEDIKKIQTQISSG----------MTNNASLLQNYLKTWDMYREIWE 967
Query: 1063 MQAENI---YNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLK 1119
+ ++ Y RL ++ + A + + + ET V++D ++ +
Sbjct: 968 INKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQH 1027
Query: 1120 YDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRK 1179
+ W + + +M + E H+ + ++ +++ + + + + V +LK
Sbjct: 1028 CNEWQNKFATLLREMAAGRLLELHTYLKENAEKISR---PPQTLEELGVSLQLVDALKHD 1084
Query: 1180 IKQFEKQVELYRNGQRLLEKQRFQFPPSWL-YIDNIEGEWGAFNDIMRRKDSAIQQQVAN 1238
+ E Q+ +LEK S L +D++ GEW F + +++
Sbjct: 1085 LANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEK 1144
Query: 1239 LQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCA 1298
+ ++ + + LL D+E T N+ AL +T ++++
Sbjct: 1145 FKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLR 1204
Query: 1299 KAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQI-DQMKEQPWVSVQPR 1357
++ + +Q +EL L+ +W E+++ WE+ ++ K ++ +Q
Sbjct: 1205 ANLGIFKIEQP-----PSKDLQNLEKELDALQQIW-EIARDWEENWNEWKTGRFLILQTE 1258
Query: 1358 KLRQNLDALLNQLKSFPARL--RQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQ 1415
+ L +L R + E + ++ + + L+ +L++ AL++RHW Q
Sbjct: 1259 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ 1318
Query: 1416 LMKRLHVNW--VVSELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTY 1473
+ + + TL QI ++ + ++ + ++ A E+A+E L+ I + W+
Sbjct: 1319 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT 1378
Query: 1474 ELDLVNYQNKCR-LIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMA 1532
+LD+V Y++K +RG +++F ++++ ++S MK S + K FE+D WE L+ I+
Sbjct: 1379 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE 1438
Query: 1533 LFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVL 1592
+ ++ + VQR+W+YLE IF G DI+ LP E+ F +++ + A+M +++K +
Sbjct: 1439 VIEMILTVQRQWMYLENIFLGE-DIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRST 1497
Query: 1593 NIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQK 1652
+ G+ +L + +L IQK+L YLE +R FPRFYF+ ++DLLEI+G S+N +Q
Sbjct: 1498 HHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQP 1557
Query: 1653 HFKKMFAGVSSIILNEDNSV-----VLGISSREGEEVMFKTPVSITEHPKINEWLTLVEK 1707
H KK F + + + + +G+ S +GE + F V + E P + WL VE+
Sbjct: 1558 HLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFL-EGP-VESWLGDVEQ 1615
Query: 1708 EMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALS 1767
MRVTL LL + F N W+ ++ Q+V+ ++QI W+ +V L
Sbjct: 1616 TMRVTLRDLLRNCHLALRKF-------LNKRDKWVKEWAGQVVITASQIQWTADVTKCLL 1668
Query: 1768 SMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIK 1827
+ D L + N LN ++++ + R K+ L+T +H RDV L K
Sbjct: 1669 TAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYK 1728
Query: 1828 SKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDR 1887
S + + SF+WLSQ+RFY++ D + I+ N +F Y +EYLG +LV TPLTDR
Sbjct: 1729 SGLMDVNSFDWLSQLRFYWEKDLDDCV----IRQTNTQFQYNYEYLGNSGRLVITPLTDR 1784
Query: 1888 CYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVG 1947
CY+T+T AL GGSP GPAGTGKTE+VK LG LG +V+V NC E D+++MGR++ G
Sbjct: 1785 CYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSG 1844
Query: 1948 LCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREH-SNPNYDKTSAPITCELLNKQV 2006
L Q GAWGCFDEFNR+ +LS V+ Q+ CI AL ++ ++D ++
Sbjct: 1845 LAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFD-----------GFEI 1893
Query: 2007 KVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLA 2066
+ IFITMNPGYAGR+ LP+NLK +FR +AM PD LIA+++L+ +GF ++LA
Sbjct: 1894 NLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILA 1953
Query: 2067 NKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGE 2126
K+ + L +QLS Q HYDFGLRAL S+L AG K+ R+Q
Sbjct: 1954 KKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAG--KKRRLQP---------------- 1995
Query: 2127 IAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVC 2186
+L ++E+L+ S+ + + KL + D PL +++ D+FP ++ + LRE +++
Sbjct: 1996 ---DLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEI 2052
Query: 2187 QEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERL-- 2244
++M G + + KV QLY+ H M+VG +GSGK+ +WR+L +L L
Sbjct: 2053 RDM------GLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCR 2106
Query: 2245 EGVEGVAHI----IDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQW 2300
G + ++PKA+S LYG D +T EWTDG+ + V+R + E +W
Sbjct: 2107 AGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRT---ACADEKPDEKW 2163
Query: 2301 IVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCG 2360
I+FDG VD W+EN+NSV+DDNK+LTL NGER+++P V ++FEV+DL A+ ATVSRCG
Sbjct: 2164 ILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCG 2223
Query: 2361 MVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAA 2420
MV+ L ++L + + E E +R E+ + ML ++D
Sbjct: 2224 MVYTDYADLGWKPYVQSWLEKR-----PKAEVEPLQRMF------EKLINKMLAFKKDNC 2272
Query: 2421 TIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFP 2480
+ P +G+ + L L+S L V P
Sbjct: 2273 KELVPLPEYSGITS--------------------LCKLYSALATPENGVN---------P 2303
Query: 2481 MQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVS 2540
E ++ V++++WS+ + R + Y+R I + PN + YE
Sbjct: 2304 ADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIEG----SFPNKDTV-YEYF 2358
Query: 2541 ISGE---WSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPP 2597
+ + W+ ++ K+P+ ++VPT+DTVR+ L+ + +A P++L GP
Sbjct: 2359 VDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPV 2418
Query: 2598 GSGKTMTLFSALRALPDME--VVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQL 2655
G+GKT S L++LP + V+ +N S+ TT + + E +RT V P
Sbjct: 2419 GTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVE-KRTKG--VYVPFG- 2474
Query: 2656 GKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPP 2715
GK ++ F D++N+P D +G+Q + IR +++G +Y + QT +K R F+ A P
Sbjct: 2475 GKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT-IKYIREMFLMAAMGP 2533
Query: 2716 TDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTF-NRAMLRLIPSLRTYAEPLTAAMV 2774
GR +S R ++ + +P + + +I+GT N+ + ++ +T A +
Sbjct: 2534 PGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATL 2593
Query: 2775 EFYTMSQERFTQD-TQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLF 2833
+ Y +RF T+ HY+++ R++++ +G+ A + + R+W HE R+F
Sbjct: 2594 DMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTK-SSITRLWIHECFRVF 2652
Query: 2834 QDRLVEDEERRWTDENIDTVALKHFPNIDREKAMS-RPILYSNWLSKDYIPVDQEEL--- 2889
DRLV+ + I F S RP ++ ++L + + D +L
Sbjct: 2653 SDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYEDLTDLTVL 2712
Query: 2890 RDYVKARLKVFYEEELDVP--LVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLS 2947
+ ++ L + VP LVLF E ++H+ RI R+ QP+G++LL+G+ G+G+ +L+
Sbjct: 2713 KTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLA 2772
Query: 2948 RFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLER 3007
R + + + +QI+V + Y ++F +D++ + R++G + + +FI ++ + D FLE
Sbjct: 2773 RLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLED 2832
Query: 3008 MNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFT 3067
+N +L++GEVP L++ DE+ + + + A+ E + +S + L+ + +V NLH+V
Sbjct: 2833 INNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVP-ESSDSLFAYLIERVQNNLHIVLC 2891
Query: 3068 MNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMP 3127
++P + ++ PAL N +NWF +W EAL +V ++ +DL I
Sbjct: 2892 LSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENI------ 2945
Query: 3128 VVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLF 3187
HR+ + V +H ++ Q + ++ R +TP YL+ ++ Y L
Sbjct: 2946 -----------HRK-VAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLL 2993
Query: 3188 HEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQ 3247
EKR EL Q L GL KI ET ++V+ + +L +++ + L +V+ +
Sbjct: 2994 GEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQK 3053
Query: 3248 QEAEKKKVMSQEIQEQLHKQQ---EVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHL 3304
+EA++++ E++ ++ + +AD + ++DL++ PA+ EA A++S+ K+ +
Sbjct: 3054 READEQQKAVTANSEKIAVEEIKCQALAD---NAQKDLEEALPALEEAMRALESLNKKDI 3110
Query: 3305 VEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIR 3364
E++S PPA V++ ++++ +L G T W + + + +NFI +++NF + ISD +
Sbjct: 3111 GEIKSYGRPPAQVEIVMQAVMILRGNEPT-WAEAKRQLGEQNFIKSLINFDKDNISDKVL 3169
Query: 3365 EKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAK 3424
+K+ Y + P + +I+ R SLA + W A Y + + VEP R + +
Sbjct: 3170 KKIGA-YCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLR 3228
Query: 3425 DNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSA 3484
+ Q E ++ +R++ + K++Y +++ + ++ +E K+ R+ L+ L+
Sbjct: 3229 EKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAG 3288
Query: 3485 ERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTT-WSHHLQQANIQF 3543
E+ RWE+T + + + + GDCLL+AAF++Y G F R + W + + +
Sbjct: 3289 EKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPC 3348
Query: 3544 RTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNE 3603
A +L N + W LP+D TEN I++ R NR+ L+IDP QA ++I N
Sbjct: 3349 SPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNM 3408
Query: 3604 YKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESY-DPVLNPVLNREVRRTGGRVLI 3662
+ + + + LE A+ FG P+L+Q+V+ Y DP LNP+LN+ V R GGR+L+
Sbjct: 3409 EGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLM 3468
Query: 3663 TLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERP 3722
+GD++++ + +F +++T+ + P+ ++ T VNF V L++Q L V++ ERP
Sbjct: 3469 RIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERP 3528
Query: 3723 DVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTR 3782
+++E++ L+ + +L++LE +L+ LNE G +LDD ++ TL K A EVT
Sbjct: 3529 ELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTE 3588
Query: 3783 KVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYE 3842
++E ++ + + Y P + S ++F + + I +YQ+SL ++ ++ + +
Sbjct: 3589 QLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDK 3648
Query: 3843 NPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYD 3902
+ + D L+ D A R L + H K+ T G+ D
Sbjct: 3649 SHRSNKLEDRIDYLN----DYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMD 3704
Query: 3903 AEFQHFLRGNEIVLSAG--STPRIQGLTVEQAEAVVRLSCLPAFKDLIAKV-QADEQFGI 3959
E+ FLRG ++ G P L + + L L F L+ Q + +
Sbjct: 3705 -EYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHL 3763
Query: 3960 WLDSSSPEQT-VPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFM 4018
W +++PE+ +P W + R+L++++ R DR+ F+ TNLG F
Sbjct: 3764 WYTNAAPEKAMLPGEWENAC------NEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRF- 3816
Query: 4019 SIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFN 4078
+E P+ V + P +P++ PG D + + LA A+ +G
Sbjct: 3817 --IEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQA 3874
Query: 4079 Q-ADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQ---PHACFRLFLTMEINPKV 4134
A + + V G WV L N HL+ W+ L+K + LQ PH FRL+L+ +P
Sbjct: 3875 PIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDF 3934
Query: 4135 PVNLLRAGRIFVFEPPPGVKANMLRTFS--SIPVSRICKSPNERARLYFLLAWFHAIIQE 4192
P+++L+ EPP G+KANM R + S P C P + +L F L +FH+++ E
Sbjct: 3935 PISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLE 3994
Query: 4193 RLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIY 4252
R ++ LGW+ Y F +SD + + + +LD+ ++ PW ALK L+A Y
Sbjct: 3995 RKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEY---------EETPWDALKYLIAGINY 4045
Query: 4253 GGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELL 4312
GG V +++D+RLL T++ F +S + F ++ + +P + +++ LL
Sbjct: 4046 GGHVTDDWDRRLLTTYINDYFCDQSLSTPFH---RLSALETYFIPKDGSLASYKEYISLL 4102
Query: 4313 PDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDG 4372
P P G NA+ T+ + +L +Q + +TR + +
Sbjct: 4103 PGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQ-----PQITPTRAGGQTREEKVLE- 4156
Query: 4373 RPAWMRTLHTTASNWLHLIPQTLSH--LKRTVENIKDPLFRFFEREVKMGAKLLQDVRQD 4430
A++ IP+ + + ++ + PL +E++ L+Q +
Sbjct: 4157 ----------LAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFS 4206
Query: 4431 LADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQ 4490
L D+ + +G + L + N + +P W P+ + W D + R++Q +
Sbjct: 4207 LTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGK-AYPSQKPLAAWTRDLAMRVEQFE 4265
Query: 4491 NISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQG 4550
++ + L G P ++TA Q A+ N+ S++ L E V+T
Sbjct: 4266 -------LWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD 4318
Query: 4551 ATL---DACSFGVTGLKLQGATCNNNKLSLSNA----ISTALPLTQLRWVKQTNTEKKAS 4603
+ L V GL L+GA + L A + +P R + K
Sbjct: 4319 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAK-G 4377
Query: 4604 VVTLPVYL------NFTRADLIFTVDFEIATKEDPRSFYERGVAVL 4643
+ + P Y + RA + +D P + +RG A+L
Sbjct: 4378 MYSCPCYYYPNRAGSSDRASFVIGIDLRSGAM-TPDHWIKRGTALL 4422
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 1408 bits (3645), Expect = 0.0
Identities = 998/3568 (27%), Positives = 1743/3568 (48%), Gaps = 280/3568 (7%)
Query: 1146 ISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFP 1205
I KS L + V+ V + ++ ++K + ++ E + LL+ + P
Sbjct: 1126 IKKSESGLLK-KVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELP 1184
Query: 1206 PS-WLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIV----QEDRAVESRTTDLLTD 1260
+ + ++ + +W N+I ++ ++QQVA LQ V Q A ++
Sbjct: 1185 ETVFKQLEELPEKW---NNI-KKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQ 1240
Query: 1261 WEKTKPVT-GNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERV 1319
+ K P ++ P + L A I ++ A E+ L + + +++
Sbjct: 1241 FHKEAPFRFDSIHPHQMLDARHI------EIQQMESTMASISESASLFEVNV--PDYKQL 1292
Query: 1320 QVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQ 1379
+ +E+ LK +W + V I + PW ++ + +++ +R
Sbjct: 1293 RQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRA 1352
Query: 1380 YASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIWDVD 1438
+ ++ ++ + + V EL++ A+++RHW+QLM+ V++ + + TL + +
Sbjct: 1353 WDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQ 1412
Query: 1439 LQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNY-QNKCRLIRGWDDLFNKV 1497
L E V+ ++ A EM +E+ LK+++ W E + + L+ +DL +
Sbjct: 1413 LHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVL 1472
Query: 1498 KEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADI 1557
+++ + + +S Y F E+ W+ KL+ + A+ +W +VQR W +LE IFTGS DI
Sbjct: 1473 EDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDI 1532
Query: 1558 KHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGE 1617
+ LP +++RF+ I +F L K P V+ N G+ LE + L +KAL E
Sbjct: 1533 RAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAE 1592
Query: 1618 YLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS-----V 1672
YL+ +R +FPRFYF+ DLL+I+ N ++Q+H K+F ++ + D S
Sbjct: 1593 YLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKT 1652
Query: 1673 VLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATS 1732
LG+ S+E E V F P + +I WL V M+ T+ + E VT E +
Sbjct: 1653 SLGMYSKEEEYVAFSEPCDCSGQVEI--WLNHVLGHMKATVRHEMTEGVTAYEEKPREQ- 1709
Query: 1733 IDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVL 1792
W+ + AQ+ + QI W+ V A + + G ++A + L L
Sbjct: 1710 --------WLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESA-MKDYYKKQVAQLKTL 1760
Query: 1793 ADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTD 1852
++ + R+K+ + T VH RDV +I K+DNA++F WLSQ+R +D D
Sbjct: 1761 ITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWD----D 1816
Query: 1853 VLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGK 1912
++ + +A+F Y +EYLG +LV TPLTDRCY+T+TQ+L + G+P GPAGTGK
Sbjct: 1817 EVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGK 1876
Query: 1913 TESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVS 1972
TE+ K LG LG V VFNC E D+++ G I+ GL Q GAWGCFDEFNR+ +LS V+
Sbjct: 1877 TETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVA 1936
Query: 1973 QQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNL 2032
QV+ IQ+A+R+ L +++ ++P + IFITMNPGYAGR+ LP+NL
Sbjct: 1937 VQVKSIQDAIRDKKQ----------WFSFLGEEISLNPSVGIFITMNPGYAGRTELPENL 1986
Query: 2033 KKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRA 2092
K LFR AM PD +LI ++ML ++GF A+ LA K + ++LC E LS Q HYD+GLRA
Sbjct: 1987 KSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRA 2046
Query: 2093 LKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAE 2152
+KSVLV AG++KR + PE ++L++S+ + +PK+V +
Sbjct: 2047 IKSVLVVAGSLKRGDPDR---------------------PEDQVLMRSLRDFNIPKIVTD 2085
Query: 2153 DIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQ 2212
D+P+ L+ D+FP + R ++K ++ L D +V KV+QL +
Sbjct: 2086 DMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDN------FVLKVVQLEE 2139
Query: 2213 ITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNT 2272
+ + H + +VG +G+GKS R L K + ++ V ++PKA++ D L+G ++P T
Sbjct: 2140 LLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKR-RPVWTDLNPKAVTNDELFGIINPAT 2198
Query: 2273 REWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGER 2332
EW DGLF+ ++R++ + +WI+ DGD+DP W+E+LN+V+DDNK+LTL + ER
Sbjct: 2199 GEWKDGLFSSIMRELANITH---DGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNER 2255
Query: 2333 LSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGED 2392
+ L P ++++FE+ L+ AT ATVSR G+++ + P D G +
Sbjct: 2256 IPLNPTMKLLFEISHLRTATPATVSRAGILYIN--------------------PADLGWN 2295
Query: 2393 EAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRL 2452
K + E A+ + + T + T + E
Sbjct: 2296 PPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQ------------- 2342
Query: 2453 RCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSG----DSRL 2508
SM+ C ++ + D P + + Y V+A +W+ G D +
Sbjct: 2343 -------SMVQMVC-HLLECLLTTEDIPADCPK--EIYEHYFVFAAIWAFGGAMVQDQLV 2392
Query: 2509 KMRAELGEY-IRRITTVPLPTAPNIPIIDYEVSI-SGEWSPWQAKVPQIEVETHKVAAPD 2566
RAE ++ + TV P+ I DY + + ++ PW VPQ E + ++
Sbjct: 2393 DYRAEFSKWWLTEFKTVKFPSQGTI--FDYYIDPETKKFEPWSKLVPQFEFDP-EMPLQA 2449
Query: 2567 VVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRAL-PDMEVV-GLNFSS 2624
+V T +T+R + +A +P++L G G+GK++ + + L +L P+ +V + F+
Sbjct: 2450 CLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNY 2509
Query: 2625 ATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIR 2684
TT +L + E + N P K L+ F D++N+P++D YGT + + IR
Sbjct: 2510 YTTSAMLQAVLEKPLEKKAGRN---YGPPG-NKKLIYFIDDMNMPEVDAYGTVQPHTIIR 2565
Query: 2685 QMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASL 2744
Q +++G +Y S + ++ +Q+V NP G ++ R RH V + +PG +L
Sbjct: 2566 QHLDYGHWYDRSKLSLKEITNVQYVSCMNPTA--GSFTINPRLQRHFSVFVLSFPGADAL 2623
Query: 2745 TQIYGTFNRAMLRL---IPSLRTYAEPLTAAMVEFYTMSQERFTQD-TQPHYIYSPREMT 2800
+ IY L+L SL+ PL + F+ F + HYI++ R+
Sbjct: 2624 SSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFA 2683
Query: 2801 RWVRGI-FEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFP 2859
+GI F ++ +++ LIR++ HE+ R+++D++VE+++ D+ V K F
Sbjct: 2684 NIFQGILFSSVECVKS--TWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFD 2741
Query: 2860 NI-DREKAMSRPILYSNWLS----KDYIPVDQEEL--RDYVKARLKVFYEEELDVPLVLF 2912
+I D + P LY ++ + Y+PV EL + V+A L+ E + LVLF
Sbjct: 2742 DIEDPVEQTQSPNLYCHFANGIGEPKYMPVQSWELLTQTLVEA-LENHNEVNTVMDLVLF 2800
Query: 2913 NEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDF 2972
+ + HV I+RI P+G+ LL+GV G+GK +L+R A+++ + V+QI + + Y +DF
Sbjct: 2801 EDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDF 2860
Query: 2973 DEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQ 3032
DL ++ ++G KN F+M ++ V D FL +N LLA+GE+P L+ DE +++
Sbjct: 2861 KMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISN 2920
Query: 3033 CKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLN 3092
+ + +GL+ D+ E +K+F ++ R L V +P L+ R+ PA+ N ++
Sbjct: 2921 VRNEVKSQGLV-DNRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIH 2979
Query: 3093 WFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQ 3152
WF +W +AL V F + +P +++I FVH
Sbjct: 2980 WFHEWPQQALESVSLRFLQNTEGIEPTV-------------------KQSISKFMAFVHT 3020
Query: 3153 TLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETV 3212
+++Q + R TP+ +L+FI Y +L H R EL+ + L GL K+ T
Sbjct: 3021 SVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTS 3080
Query: 3213 DQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIA 3272
QV++L+ L + EL+ KN A+ ++ + + + ++K M+ E ++++ +
Sbjct: 3081 AQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVK 3140
Query: 3273 DKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGE-- 3330
KQ +EDL K EPA+ AQ A+ ++ K +L E++S +PP AV ++ +L+
Sbjct: 3141 QKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRG 3200
Query: 3331 ---STTDWKQIRSIIMR-ENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRAS 3386
WK + + + + F+ +++NF+ E I + + ++ Y+ +P +N E V S
Sbjct: 3201 RVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRP-YLQDPEFNPEFVATKS 3259
Query: 3387 LACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIAR 3446
A + W I + + ++ VEP R L K D Q+K ++ I L ++A+
Sbjct: 3260 YAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAK 3319
Query: 3447 YKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGD 3506
+ ++ + + ++ + L+ L++E RW + FK Q T+ GD
Sbjct: 3320 LTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGD 3379
Query: 3507 CLLSAAFIAYAGYFDQQMRQNLFT-TWSHHLQQAN--IQFRTDIARTEYLSNADERLRWQ 3563
LL AFI+Y G+F ++ RQ+L TW +L Q I + L + + WQ
Sbjct: 3380 ILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQ 3439
Query: 3564 ASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEY-KDRKITRTSFLDDAFRKN 3622
LPAD + ENA +L R+PL++DP Q ++I N+Y +D ++T+ + +
Sbjct: 3440 NEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGEDLRVTQIG--QKGYLQI 3497
Query: 3623 LESALRFGNPLLVQDVE-SYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLST 3681
+E AL G +L++++E S DPVL P+L REV + G I +GD++ + +P F + L T
Sbjct: 3498 IEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGR--FIKIGDKECEYNPKFRLILHT 3555
Query: 3682 RDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLR 3741
+ + P+L ++ T +NFTVTR L+ Q L V+ ERPD+++ +SDL K Q F++
Sbjct: 3556 KLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKIT 3615
Query: 3742 LRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQY 3801
L+ LE SLL L+ G L + ++ LE K+ AAEV +KV+E + ++ + Y
Sbjct: 3616 LKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHY 3675
Query: 3802 LPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHT--QRLSII 3859
P + S +YF M L +IH +YQ+SL+ F +++++ + D + +R++ +
Sbjct: 3676 RPAAARASLLYFIMNDLSKIHPMYQFSLKAF-----SIVFQKAVERAAPDESLRERVANL 3730
Query: 3860 TKDLFQVAFNRVARGMLHQDHITF-AMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSA 3918
+ + RG+ D +T+ A L +I L + E LR +
Sbjct: 3731 IDSITFSVYQYTIRGLFECDKLTYLAQLTFQILL---MNREVNAVELDFLLRS---PVQT 3784
Query: 3919 GSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSSPE-QTVPYLWSE 3976
G+ ++ L+ + AV LS + F +L ++ + + +++S PE + +P W
Sbjct: 3785 GTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKN 3844
Query: 3977 ETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVK 4036
+T A+ RL +++A RPDR+ FV LG + ++ + LD E
Sbjct: 3845 KT-------ALQRLCMLRAMRPDRMTYALRDFVEEKLGSKY--VVGRALDFATSF-EESG 3894
Query: 4037 PNTPVLMCSVPGYDASGHVEDLAAE-----QNTQITSIAIGSAEGFNQADKAINTAVKSG 4091
P TP+ PG D VE + N ++++G + A+ A++ A K G
Sbjct: 3895 PATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEV-VAEAALDLAAKKG 3953
Query: 4092 RWVMLKNVHLAPGWLMQLEKKL--HSLQPHACFRLFLTMEINPK-----VPVNLLRAGRI 4144
WV+L+N+HL WL LEKKL HS H FR+F++ E P +P +L
Sbjct: 3954 HWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIK 4013
Query: 4145 FVFEPPPGVKANMLRTFSSI--PVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWS 4202
EPP G+ AN+ + + +C E + F L +FHA++ ER ++ P GW+
Sbjct: 4014 ITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWN 4073
Query: 4203 KKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQ 4262
+ Y F DL + + + +L+ A K+P+ L+ L + +YGG + +++D+
Sbjct: 4074 RSYPFNTGDLTISVNVLYNFLEANA---------KVPYDDLRYLFGEIMYGGHITDDWDR 4124
Query: 4263 RLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLG 4322
RL T+L + E LA +P + + Q+++ ++P G
Sbjct: 4125 RLCRTYLGEFIRPEMLEGELSLA------PGFPLPGNMDYNGYHQYIDAELPPESPYLYG 4178
Query: 4323 LPNNAERVLLTTQGVDMISKMLKMQMLEDE-DDLAYAETEKKTRTDSTSDGRPAWMRTLH 4381
L NAE LT + +L++Q + + D A A E+K + A + +
Sbjct: 4179 LHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVK---------ALLEEIL 4229
Query: 4382 TTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGK 4441
++ + IP+ ++ ++ + P +E L +++++ L ++ +G+
Sbjct: 4230 ERVTDEFN-IPELMAKVEE-----RTPYIVVAFQECGRMNILTREIQRSLRELELGLKGE 4283
Query: 4442 KKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGA 4501
T+++ L N L ++P SW+ P+ + W D RIK+L+ A G
Sbjct: 4284 LTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELE------AWTGD 4337
Query: 4502 KELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDAC---SF 4558
+ + V L G F P++++TA Q A+ N W L+++ L+ ++T +
Sbjct: 4338 FTMPST-VWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGA 4396
Query: 4559 GVTGLKLQGATCNNNKLSLSNA-ISTALPLTQLRWVKQTNTEKK--ASVVTLPVYLNFTR 4615
+ GL ++GA + ++ A + P + ++K +K+ SV + PVY R
Sbjct: 4397 YIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR 4456
Query: 4616 ADLIFTVDFEIATKEDPRSFYERGVAVL 4643
+ F + TKE+P + GVA+L
Sbjct: 4457 GP-TYVWTFNLKTKENPSKWVLAGVALL 4483
Score = 53.5 bits (127), Expect = 5e-06
Identities = 102/635 (16%), Positives = 249/635 (39%), Gaps = 65/635 (10%)
Query: 238 DPTFLNQLQSGVNRWIREIQKVTKLDRDPA-----SGTALQEISFWLNLERALYRIQEKR 292
D + + ++S V +W ++Q V K + + T E+ FW + R ++ +
Sbjct: 210 DKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKS------RYEDLK 263
Query: 293 ESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETV-NDYNPLMKDFPLNDLLSATELD 351
L T+ + G+ + L+ + + Y P K + + + E
Sbjct: 264 YIYNQLRTITV----------------RGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQ 307
Query: 352 KIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEK 411
I L+ + HL + N ++P V+ R L + + T K +Y +
Sbjct: 308 DIHVHLIPLQRHLEALENAEFPE------VKPQLRPLLHVVCLIWATCK----SYRSPGR 357
Query: 412 VMVACFEVFQTWDDE---YEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRK 468
+ V E+ + Y + LLR V+ + + + ++ ++ Q R + +
Sbjct: 358 LTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHT 417
Query: 469 FRRQHEQLR-----AVIVRVLRPQVTAVAQQNQGEVPEPQDM-KVAEVLFDAADANAI-E 521
+ +++++++ + +V V +G + D K+ +V F NA+ +
Sbjct: 418 YFKENQEVKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQ 477
Query: 522 EVNLAYENVKEVDGL------DVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTA 575
+V +E +E+ L D + +E + ++++++ ++ R+ A
Sbjct: 478 QVQQMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDA 537
Query: 576 KNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKM 635
F++ L RP + + LIQ D++++ + +
Sbjct: 538 PGLEHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGF 597
Query: 636 SHV-RDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLN 694
S V +++P V+G + WA+++ +++ + E+ EG++++Q + L
Sbjct: 598 SPVHKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMES-AEGKRMQQKYEDMLSLLE 656
Query: 695 TQE--IFDDWARKVQQRNLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRN 752
E +++DW R V +++ + + ++ R ++ +NF P++I++ KE+
Sbjct: 657 KYETRLYEDWCRTVSEKSQ------YNLSQPLLK-RDPETKEITINFNPQLISVLKEMSY 709
Query: 753 LKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKKEV 812
L+ + + Y ++ +E + + K L+ L+
Sbjct: 710 LEPREMKHMPETAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNID 769
Query: 813 QALIAEGIALVWESYKLDPYVQRLAETVFNFQEKV 847
L A L W++ + YV + ++ + ++++
Sbjct: 770 LRLRAAEETLNWKTEGICDYVTEITSSIHDLEQRI 804
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 1397 bits (3616), Expect = 0.0
Identities = 1014/3626 (27%), Positives = 1770/3626 (48%), Gaps = 340/3626 (9%)
Query: 1162 STSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYI-----DNIEG 1216
+T++ V + ++ ++ +I+ E + + +L+E+ + PP + +I
Sbjct: 726 TTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMKPSIVA 785
Query: 1217 EWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAV--------ESRTTDLLTDWEKTKPVT 1268
A + + ++S+I+Q +L + + + V + + D+ D +K + +
Sbjct: 786 VRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLIL 845
Query: 1269 GNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQD 1328
NL+ A ++ K + K+ + + +K EALE E ++ L++L
Sbjct: 846 NNLQSVLADLQKRAFQYKSYQ-KNFKVEVSKF-EALE----------EVSAELKLKQL-- 891
Query: 1329 LKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQR 1388
+W S+ W+++ +Q W L+ D L ++ + ++ +YA +FV +
Sbjct: 892 ---LWDSFSE-WDKL----QQEW-------LKSKFDCLDPEVLN--GQVSKYA--KFVTQ 932
Query: 1389 LLKGY---------------MKINM-LVIELKSEALKDRHWKQLMKRLHVNWVVSE--LT 1430
L KG MK + ++I+L++ LK RHW + + + V +E LT
Sbjct: 933 LEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLT 992
Query: 1431 LGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNK--CRLIR 1488
L ++ + + ++D+ A GE ALE LK++ + W T E ++ +++ ++
Sbjct: 993 LERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFVILPHRDSKDVFILG 1052
Query: 1489 GWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLE 1548
G DD+ + + +V+ + S Y + W+ +L + W+ QR W+YLE
Sbjct: 1053 GTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLE 1112
Query: 1549 GIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLL 1608
IF + DI+ LP E + F + + +M+KV++ P + G+ + + LL
Sbjct: 1113 SIFN-APDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALL 1171
Query: 1609 GKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSI---- 1664
+IQK L YLE +R FPRFYF+ +++LLEI+ ++N +Q H +K F +S +
Sbjct: 1172 DQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFAL 1231
Query: 1665 ----------ILNEDNSV----VLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMR 1710
I E V +L + S EGE V + + EWL VE+ M
Sbjct: 1232 MPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGK--GLKARGNVEEWLGKVEEAMF 1289
Query: 1711 VTLAKLLAESVTEVEIFGKATSIDPNTYITWIDK-YQAQLVVLSAQIAWSENVETALSSM 1769
+L +L ++ + + GK + W+ + +Q+++ +QI W ++ L +
Sbjct: 1290 TSLRRLCKAAIADYQ--GKLRT-------DWVVAGHPSQVILTVSQIMWCRDLTECLETE 1340
Query: 1770 GGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSK 1829
A + N E LN LA V P L R L LIT VH RD+ L++SK
Sbjct: 1341 HSNHIQALKNFEKVNFE-RLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQSK 1399
Query: 1830 IDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCY 1889
++ +SF+W Q+R+Y+D L +MA +++ YG+EYLG +LV TPLTDRCY
Sbjct: 1400 VETVESFDWQRQLRYYWDID----LDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCY 1455
Query: 1890 LTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLC 1949
L + AL+ LGG+P GPAGTGKTE+ K L L +VFNC + D++ MGR F GL
Sbjct: 1456 LCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLA 1515
Query: 1950 QVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVS 2009
Q GAW CFDEFNR++ +LS ++QQ+ I+ A K + +++K+
Sbjct: 1516 QSGAWCCFDEFNRIDIEVLSVIAQQLITIRNA----------KAAKLSRFMFEGREIKLV 1565
Query: 2010 PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKI 2069
A FITMNPGYAGR+ LPDNLK LFR AM P+ LIA+V+LYS+GF ++++LA K+
Sbjct: 1566 MTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKM 1625
Query: 2070 VPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAE 2129
+KLC EQLS Q HYDFG+RA+KSVLV AG++KRE
Sbjct: 1626 TQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKREN---------------------P 1664
Query: 2130 NLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEM 2189
+L E +LI+++ ++ +PK + +D L ++SD+FPGVQ + L+ + V
Sbjct: 1665 DLNEDVVLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQ 1724
Query: 2190 YLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLE--GV 2247
L + V KV+Q Y+ + HG+M+VGP+G GK+ +R+L + L L+ G+
Sbjct: 1725 NL------QPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGI 1778
Query: 2248 EGV------AHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWI 2301
E ++++PK+I+ LYG ++ T EW DGL +R ++ + +WI
Sbjct: 1779 ENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTS---EDHKWI 1835
Query: 2302 VFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGM 2361
+ DG VD W+EN+N+VLDDNK+L L N ER+ L P + ++FEVQDL+ A+ ATVSRCGM
Sbjct: 1836 ISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGM 1895
Query: 2362 VWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAAT 2421
V+ + L ++ + +E ++ + DEG
Sbjct: 1896 VFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLH-------------- 1941
Query: 2422 IMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPM 2481
+ K A I +T L CL L S++ + + M
Sbjct: 1942 ----------FINKKCSQAIPQVDISKVTTLCCL--LESLI---------LGKDGVNLAM 1980
Query: 2482 QIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRI----TTVPLPTAPNIPIIDY 2537
+ +L + + V+ LWSL G+ +IR LP + ++ I
Sbjct: 1981 EQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHM 2040
Query: 2538 EVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPP 2597
+ PW+ +P + V +++VPT DTVR+ L+ LA ++ G
Sbjct: 2041 DFDTK-RLDPWERIIPTFKYN-RDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGIT 2098
Query: 2598 GSGKTMTLFSALRALPDME---VVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQ 2654
G GK++ L + + V LNFS+ T+ + + E +R ++ AP
Sbjct: 2099 GVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKR--KNILGAPGN 2156
Query: 2655 LGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNP 2714
K +V+F D++N+P +D+YG+Q I +RQ + GGFY + W +++ + + AC P
Sbjct: 2157 --KRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAP 2214
Query: 2715 PTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIY-GTFNRAMLRLIPSLRTYAEPLTAAM 2773
P GR P++ RF+RH ++ + P SL QI+ N + P+++ A + A
Sbjct: 2215 PGG-GRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEAS 2273
Query: 2774 VEFYT-MSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRL 2832
VE Y MS + + HY+++ R++++ V+GI + P + R++ HE R+
Sbjct: 2274 VEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQC-DPGTIREEIQIFRLFCHECQRV 2332
Query: 2833 FQDRLVEDEERRWTDENIDTVALKHFP-NIDREKAMSRPILYSNWLSKDYIPVDQ--EEL 2889
F DRL+ +E++ + + +A KHF ID E +++PI++ +++ D+ +++
Sbjct: 2333 FHDRLINNEDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDM 2392
Query: 2890 RDYVK-ARLKVFYEEEL------DVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAG 2942
D K A + Y ++ +V LV F + ++HV RI R+ RQ +G+ LL+GV G G
Sbjct: 2393 PDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTG 2452
Query: 2943 KTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDS 3002
K +L+R A + G QI++ R Y + F EDLR + + +G +++ + F+ ++ ++
Sbjct: 2453 KQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVE 2512
Query: 3003 GFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNL 3062
FLE +N +L +GEVP LFE DE ++ + A++ G+ + +E++++F S+V + L
Sbjct: 2513 EFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKL 2572
Query: 3063 HVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIV 3122
H+V M+P E + R P+L N C ++WF W EAL V K F S++D
Sbjct: 2573 HIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEE--- 2629
Query: 3123 PDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINH 3182
+ +KLP CV VH ++ R R TP YL+ IN
Sbjct: 2630 ------LKEKLPL----------MCVNVHLSVSSMAERYYNELRRRYYTTPTSYLELINL 2673
Query: 3183 YANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKK 3242
Y ++ EKR ++ + + GL K+ ET V++++ DL L K+ ++K
Sbjct: 2674 YLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEK 2733
Query: 3243 MVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQ 3302
+ DQ+ A++ + QE + + E + DLD+ PA+ A A+ S+ K
Sbjct: 2734 LAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPALDAANKALDSLDKA 2793
Query: 3303 HLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDA 3362
+ E+R PP V +E+I +LL + DW + ++ NF+ ++ + E I
Sbjct: 2794 DISEIRVFTKPPDLVMTVMEAISILL-NAKPDWPSAKQLLGDSNFLKRLLEYDKENIKPQ 2852
Query: 3363 IREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDD 3422
I K++K Y++NP + E V + S AC M W A Y+ ++K VEP R +L+ + +
Sbjct: 2853 ILAKLQK-YINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAE 2911
Query: 3423 AKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSL 3482
E + ++R +E I ++EY ++E +++ +A +A++ R+ L +L
Sbjct: 2912 LDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAAL 2971
Query: 3483 SAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQ 3542
E+ RWE++ + F+ ++S I G+ ++AA +AY G F Q RQ+L W Q I
Sbjct: 2972 EDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIP 3031
Query: 3543 FRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMN 3602
+ L + E +W LP D + TEN I++ + R+PL+IDP QA +I N
Sbjct: 3032 IDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRN 3091
Query: 3603 EYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVL 3661
+ + D F + LE+++R G P+L++++ E+ DP L P+L +++ +GGR+L
Sbjct: 3092 KESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPALEPILLKQIFISGGRLL 3151
Query: 3662 ITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAER 3721
I LGD DID +F +++T+ P + P++C +VT +NFTVT+S L+ Q L++V++ E+
Sbjct: 3152 IRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEK 3211
Query: 3722 PDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVT 3781
P ++E+R L+ + +L+ +E+ +L+ L +G ILD++ +I TL++ K + +
Sbjct: 3212 PRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIK 3271
Query: 3782 RKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLY 3841
++EE + Q + ++Y P++T S +YF + SL +I +YQYSL++F +++ +
Sbjct: 3272 TRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIE 3331
Query: 3842 ENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLA--RIKLKGTVGEP 3899
+ + + QRL ++ + A+ V+RG+ Q + ++ +L ++ +GT+
Sbjct: 3332 TSVKTENL---QQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLS-- 3386
Query: 3900 TYDAEFQHFLRGNE-IVLSAGSTPRIQGLTVEQAEAVVRL-SCLPAFKDLIAKVQADE-- 3955
DAE+ FLRG+ + P L A L P F L + +
Sbjct: 3387 --DAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDLEESFPVFHGLTQNILSHPIS 3444
Query: 3956 -QFGIWLDSSSPEQTVPYL--------------WSEETPATPIGQAIHRLLLIQAFRPDR 4000
+ G + +P++ Y + + P + + H+L+LI+ + ++
Sbjct: 3445 IRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEK 3504
Query: 4001 LLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAA 4060
++ FV NLG+ F I P+DL + ++ NTP++ G D G + A
Sbjct: 3505 VVFALTDFVIENLGKQF--IETPPVDLPTLY-QDMSCNTPLVFILSTGSDPMGAFQRFAR 3561
Query: 4061 EQ--NTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSL-Q 4117
E + ++ SI++G +G A+K + A+KSG WV L+N HLA W++ +E+ + +
Sbjct: 3562 ESGYSERVQSISLGQGQG-PIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTD 3620
Query: 4118 PHAC----FRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKS- 4172
P + FRLFL+ + PV +L+ EPP G++AN+ R F+ + S ++
Sbjct: 3621 PDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFFEENI 3680
Query: 4173 -PNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQ 4231
+ ++ F + +FHAIIQER ++ PLGW+ YEF +SD A + + +
Sbjct: 3681 LGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCKE------ 3734
Query: 4232 NISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGH 4291
KIPW AL + + YGGRV + +DQR L T L+R F+ + + ++K + G
Sbjct: 3735 ----GKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYS--ESGI 3788
Query: 4292 KDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLED 4351
M D + +EF ++E LP P G+ NA V + +I+ +L++Q
Sbjct: 3789 YFAPMADSL--QEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSS 3846
Query: 4352 EDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFR 4411
E K+ + + + ++ T L + + S + ++ + L
Sbjct: 3847 TGG------EGKSNDEIVQE----LVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTT 3896
Query: 4412 FFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPA 4471
+EV LL+ + L + + G + + + N + +P WS+ P+
Sbjct: 3897 VLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPS 3956
Query: 4472 GMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQA 4531
+ WV D I + + L G K + G F P+ ++T T Q A+
Sbjct: 3957 LKPLGSWVKDL---ILRTSFVDLWLKRGQPKS-----YWISGFFFPQGFLTGTLQNHARK 4008
Query: 4532 NSWSLEELCLEVNVTTS---QGATLDAC---SFG-----------------VTGLKLQGA 4568
+ ++EL + +V + Q A ++A FG V G+ + +
Sbjct: 4009 YNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDAS 4068
Query: 4569 TCNNNKLSLSNAISTAL--PLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLI------- 4619
++ ++ + +A+ + L + + Q N + ++ P+Y RA +
Sbjct: 4069 RWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYKPSPTLYHCPLYKTGARAGTLSTTGHST 4128
Query: 4620 -FTVDFEIATKEDPRSFYERGVAVLC 4644
F V + +K + +G A+LC
Sbjct: 4129 NFVVTVLLPSKRSKDYWIAKGSALLC 4154
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 1384 bits (3581), Expect = 0.0
Identities = 973/3456 (28%), Positives = 1692/3456 (48%), Gaps = 333/3456 (9%)
Query: 1317 ERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQN-------LDALLNQ 1369
+++ ++E Q +W+ S + P ++ +L +N + + Q
Sbjct: 1011 DKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQ 1070
Query: 1370 LKSFPARLRQYASYEFVQRL--LKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNW-VV 1426
K PA Q + + R+ K Y+ L+ L++ ++ RHW+ L ++++N
Sbjct: 1071 FKDMPAC--QEVALDIRARIEEFKPYIP---LIQGLRNPGMRIRHWETLSNQININVRPK 1125
Query: 1427 SELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQ-NKCR 1485
+ LT + +++LQ + + V VA E A+E+ L ++ + W+T +++ Y+
Sbjct: 1126 ANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTY 1185
Query: 1486 LIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWV 1545
+++ D+ + +HI M SPY K FE+ SWE+KL + + W++ QR W+
Sbjct: 1186 ILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWL 1245
Query: 1546 YLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLA 1605
YLE IF+ S DI LPVE++R+Q++ + +MK ++ +V+N+ R L+ L
Sbjct: 1246 YLEPIFS-SEDINQQLPVESKRYQTMERIWKKIMKNAYEN---REVINVCSDLRMLDSLR 1301
Query: 1606 D---LLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVS 1662
D +L +QK L EYLE +RS+FPRFYF+ D++LLEI+ +K+ +Q H +K F ++
Sbjct: 1302 DCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIA 1361
Query: 1663 SIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVT 1722
++ ED + + S EGEEV SI + +WL VE+ M+ ++ ++ +++
Sbjct: 1362 RLLFQEDLEIT-HMYSAEGEEVQLC--FSIYPSSNVEDWLREVERSMKASVHDIIEKAI- 1417
Query: 1723 EVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVL 1782
+A P T W+ + Q+ + Q W+ V AL +A L S L
Sbjct: 1418 ------RAYPTMPRTQ--WVLNWPGQVTIAGCQTYWTMEVAEAL-------EAGNLRSQL 1462
Query: 1783 SNVEVTLNVLADSVLMEQPPLRRRK---LEHLITELVHQRDVTRSLIKSKIDNAKSFEWL 1839
L+D V + + L R + L LI VH +DV LI+ + + F+W+
Sbjct: 1463 --FPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWI 1520
Query: 1840 SQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEAR 1899
SQ+R+Y+ L I+ NA+F YG+EYLG +LV TPLTDRCYLT+T AL +
Sbjct: 1521 SQLRYYWTNND------LYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLK 1574
Query: 1900 LGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDE 1959
GG+P GPAGTGKTE+ K LG L +VFNC + DF AMG+ F GL GAW CFDE
Sbjct: 1575 FGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDE 1634
Query: 1960 FNRLEERMLSAVSQQVQCIQEALREHSNP-NYDKTSAPITCELLNKQVKVSPDMAIFITM 2018
FNR++ +LS V+QQ+ IQ+A ++ ++ P+ P A+FITM
Sbjct: 1635 FNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLV-----------PSCAVFITM 1683
Query: 2019 NPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDE 2078
NPGYAGR+ LPDNLK LFR +AM PD +I ++ LYS GF A VLA KI FKL E
Sbjct: 1684 NPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSE 1743
Query: 2079 QLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILI 2138
QLSSQ HYDFG+RA+K+V+ +AGN+KRE ++ E+ I +
Sbjct: 1744 QLSSQDHYDFGMRAVKTVISAAGNLKREN---------------------PSMNEELICL 1782
Query: 2139 QSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEE 2198
+++ + VPK + ED+ L ++SD+FP ++ + L E +++ C+ L +G
Sbjct: 1783 RAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEG-- 1840
Query: 2199 VGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVA------- 2251
++ K +QLY+ T + HGLM+VGP+GSGKS +RVL A+ L+G ++
Sbjct: 1841 ----FLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAV 1896
Query: 2252 --HIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDP 2309
++++PK+I+ LYG D T EWTDG+F+ +R ++ + K+ W +FDG VD
Sbjct: 1897 NYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRA--GAITSDTNKK-WYMFDGPVDA 1953
Query: 2310 EWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVL 2369
W+EN+N+VLDDNK L L +GE + L + +MFEVQDL A+ ATVSRCGMV+ +L
Sbjct: 1954 IWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSIL 2013
Query: 2370 STDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQ--IQRDAATIMQPYF 2427
+L +L + K E+ + L+ I +++ +
Sbjct: 2014 GLMPFIECWLRKLPPL------------LKPYEEHFKALFVSFLEESISFVRSSVKEVIA 2061
Query: 2428 TSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLE 2487
++N +T +L L L C F + + + + ++ ++
Sbjct: 2062 STNCNLTMSL-----------LKLLDCFFKPF-LPREGLKKIPSE---------KLSRIV 2100
Query: 2488 RYIQRYLVYAILWSLSGDSRLKMRAELGEYIR---RITTVPLPTAPNIPIIDYEVSISG- 2543
I+ + +++++WS+ R ++R + L + DY + +G
Sbjct: 2101 ELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGI 2160
Query: 2544 ----------------EWSPWQ-AKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLA 2586
W W + P V +++VPT+DTV+ LL L
Sbjct: 2161 SGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYC--NIIVPTMDTVQMSHLLDMLLT 2218
Query: 2587 EHKPLVLCGPPGSGKTMTLFSALRALPDMEVVG--LNFSSATTPELLLKTFDHYCEYRRT 2644
KP++ GP G+GKT+T+ L ++ + L FS+ T+ D + RR
Sbjct: 2219 NKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRR- 2277
Query: 2645 PNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY-RTSDQTWVKL 2703
GV P LG+ + F D++N+P ++ YG Q I +RQ ++HGG+Y R + L
Sbjct: 2278 -KGVFGPP--LGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNL 2334
Query: 2704 ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTF------------ 2751
I FV A PP GR ++ R +RH + S +I+ T
Sbjct: 2335 VDINFVCAMGPPGG-GRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEK 2393
Query: 2752 -NRAMLRLIPSLRTYAEPLTAAMVEFY-TMSQERFTQDTQPHYIYSPREMTRWVRGIFEA 2809
R + P + + EPL A + Y T++ + + HY ++ R++++ +G+ A
Sbjct: 2394 SYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMA 2453
Query: 2810 LRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSR 2869
P + L+R+W HE R+F+DRLV +E+R W D+ + ++ + + +
Sbjct: 2454 -DPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKR-CMEQWEVTFNKVCPFQ 2511
Query: 2870 PILYSNWLS-----KDYIPVDQEE-----LRDYVKARLKVFYEEELDVPLVLFNEVLDHV 2919
PILY +++S K Y + E + +Y++ ++ + LVLF + + H+
Sbjct: 2512 PILYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQI---NTAKLKLVLFMDAMSHI 2568
Query: 2920 LRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTV 2979
RI R RQ G+ LL+GV G+G+++L+R + M +QI++ + Y ++ +D++ V
Sbjct: 2569 CRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKV 2628
Query: 2980 LRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQK 3039
L ++G +N I F+ ++ + + FLE +N +L +G++P L+ DE +++ + Q+
Sbjct: 2629 LLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQE 2688
Query: 3040 EGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWST 3099
+GL + L +T +V N+H+V M+P E + R P+L N C ++WF +W
Sbjct: 2689 QGLQ-PTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPA 2747
Query: 3100 EALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANA 3159
EAL V F +++ +L + ++ CV++HQ++ +
Sbjct: 2748 EALKSVATVFLNEIP-----------------ELESSQEEIQGLIQVCVYIHQSVSKKCI 2790
Query: 3160 RLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELR 3219
R +TP+ YL+ ++ ++ L +K+ EL+ + + GL K+ T + V +++
Sbjct: 2791 EYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQ 2850
Query: 3220 RDLRIKSQELEVKNAAANDKLKKMVKDQ-----QEAEKKKVMSQEIQ--EQLHKQQEVIA 3272
DL LE AA D + M + + E + V ++EI+ E+ K Q +
Sbjct: 2851 EDLESMHPLLE---EAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIAD 2907
Query: 3273 DKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGEST 3332
D Q +DLD+ PA+ A +++++ K + EVR+M PP VKL +E++C++ G
Sbjct: 2908 DAQ----KDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKP 2963
Query: 3333 TD-------------WKQIRSIIMRE-NFIPTIVNFSAEEISDAIREKMKKNYMSNPSYN 3378
W+ + ++ +F+ ++ F + I D + + ++ Y+ N +
Sbjct: 2964 KKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQP-YIDNEEFQ 3022
Query: 3379 YEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIR 3438
+ + S AC + +W A Y + K VEP R L + +DD Q+ +E +Q +R
Sbjct: 3023 PATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLR 3082
Query: 3439 DLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKN 3498
++E IA + +Y I++ + ++ E ++ R+ L+ LS E+ RW++T E +
Sbjct: 3083 EVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQY 3142
Query: 3499 QMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADE 3558
++ I+GD L++A F+AY G F Q R L+ +W L+ N+ ++ L N +
Sbjct: 3143 MLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVK 3202
Query: 3559 RLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDA 3618
WQ + LP D L EN ++ + R+ IDP QA ++I N KD + D
Sbjct: 3203 IRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRD 3262
Query: 3619 FRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVI 3677
F +++E+A+RFG P L+++V E DP L PVL ++ + G ++ LGD I F +
Sbjct: 3263 FLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRM 3322
Query: 3678 FLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGE 3737
+++T+ P + P++ +++T +NFT++ S L+ Q L +V+ ERPD++E ++ L+ +
Sbjct: 3323 YITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAK 3382
Query: 3738 FQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETV 3797
+ L+ +E +L L+ +G +DD +I LE K +AAE+ KV + ++++
Sbjct: 3383 MRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLT 3442
Query: 3798 SQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLS 3857
+Y+P++ ++F + L + +YQYSL++FL+I+ L N + + +R+S
Sbjct: 3443 RMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIF---LSGIANSERADNLKKRIS 3499
Query: 3858 IITKDLFQVAFNRVARGMLHQDHITFAMLL-ARIKL-KGTVGEPTYDAEFQHFLRGNEIV 3915
I + L ++ V R + + + FA LL RI + +G + + +E+++ L G I
Sbjct: 3500 NINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQ----SEWRYLLSGGSIS 3555
Query: 3916 LSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAK-VQADEQFGIWLDSSSP-EQTVPYL 3973
+ P L+ ++ LS LP F + V+ +F + DS P + +P +
Sbjct: 3556 IMT-ENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGI 3614
Query: 3974 WSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGT 4033
W + +LL+++ R D++ FV+TNL F I Q +L+ +V
Sbjct: 3615 WDQYL------DQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRF--IEPQTANLS-VVFK 3665
Query: 4034 EVKPNTPVLMCSVPGYDASGHVEDLAAEQ--NTQITSIAIGSAEGFNQADKAINTAVKSG 4091
+ TP++ PG D + + A E + ++++I++G +G +A+ + ++++ G
Sbjct: 3666 DSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQG-PRAEAMMRSSIERG 3724
Query: 4092 RWVMLKNVHLAPGWLMQLEKKLHSLQP---HACFRLFLTMEINPKVPVNLLRAGRIFVFE 4148
+WV +N HLAP W+ LE+ + + P H FRL+LT + K PV++L+ G E
Sbjct: 3725 KWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIE 3784
Query: 4149 PPPGVKANMLRTFSSIPVSRI--CKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYE 4206
PP GV+AN+L+++SS+ + C E L L FH ER ++ PLG++ YE
Sbjct: 3785 PPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYE 3844
Query: 4207 FGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLN 4266
F + DLR + +LD+ D IP+ LK + YGGRV +++D+R +
Sbjct: 3845 FTDGDLRICISQLKMFLDEY---------DDIPYKVLKYTAGEINYGGRVTDDWDRRCIM 3895
Query: 4267 TFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNN 4326
LE + E + H Q+P ++ +++ LP P GL +N
Sbjct: 3896 NILEDFYNPDVLSPEHSYSASGIYH---QIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDN 3952
Query: 4327 AERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASN 4386
A + ++ ++++Q S+S G + N
Sbjct: 3953 ANITFAQNETFALLGTIIQLQ------------------PKSSSAGSQGREEIVEDVTQN 3994
Query: 4387 WLHLIPQTLS---HLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKK 4443
L +P+ ++ + + ++ + +EV +LLQ + Q L D+++ +G
Sbjct: 3995 ILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVV 4054
Query: 4444 QTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKE 4503
++ L + L +P WS P+ + WV D +R+ LQ A G
Sbjct: 4055 MSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQ----AWIQDGIPA 4110
Query: 4504 LKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNV---TTSQGATLDACSFGV 4560
+ + G F P+A++T T Q A+ S++ + + V S+ +
Sbjct: 4111 V----FWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYI 4166
Query: 4561 TGLKLQGATCNNNKLSLSNAISTALPLTQLR--WVKQTNTEK--KASVVTLPVYLNFTRA 4616
GL L+GA + L+ + L T++ W+ T K P+Y TRA
Sbjct: 4167 HGLFLEGARWDPEAFQLAESQPKEL-YTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRA 4225
Query: 4617 DLI--------FTVDFEIATKEDPRSFYERGVAVLC 4644
+ + + EI T + R + +RGVA++C
Sbjct: 4226 GTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALIC 4261
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 1368 bits (3540), Expect = 0.0
Identities = 949/3400 (27%), Positives = 1675/3400 (49%), Gaps = 281/3400 (8%)
Query: 1317 ERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPAR 1376
++++ E++ LK +W + V I+ K W + ++ + ++S
Sbjct: 1276 KQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKE 1335
Query: 1377 LRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIW 1435
++ + ++ + +K + V EL++ A+++RHW+QLM+ V + +SE TL +
Sbjct: 1336 MKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLL 1395
Query: 1436 DVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNY-QNKCRLIRGWDDLF 1494
++L E V++++ A E +E+ LK + W+ E + + +++ + L
Sbjct: 1396 QLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLV 1455
Query: 1495 NKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGS 1554
++++ + + +S Y F ++ SW+ KL+ ++ +W +VQR W +LE IF GS
Sbjct: 1456 ETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGS 1515
Query: 1555 ADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKA 1614
DI+ LP ++QRF I+ EF ALM+ K+P V++ + G+ LE L L +KA
Sbjct: 1516 EDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKA 1575
Query: 1615 LGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS--- 1671
L EYLE +R +FPRFYFV DLL+I+ N + ++ +H K+F + + D S
Sbjct: 1576 LAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKP 1635
Query: 1672 --VVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGK 1729
V LG+ S+E E ++F ++ ++ WL V M TL + E+V E +
Sbjct: 1636 LKVGLGMYSKEDEYMVFDQECDLSGQVEV--WLNRVLDRMCSTLRHEIPEAVVTYEEKPR 1693
Query: 1730 ATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTL 1789
WI Y AQ+ + QI W+ V A + + G + A + L
Sbjct: 1694 EQ---------WILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENA-IRDYNKKQISQL 1743
Query: 1790 NVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPK 1849
NVL ++ R K+ + T VH RDV +I +K++++++F W +Q+R +D +
Sbjct: 1744 NVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEE 1803
Query: 1850 QTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAG 1909
+ + +A+ Y +EYLG +LV TPLTDRCY+T+TQ+L +GG+P GPAG
Sbjct: 1804 KRHCFANI----CDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAG 1859
Query: 1910 TGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLS 1969
TGKTE+ K LG LG V VFNC E D+++ G I+ GL Q GAWGCFDEFNR+ +LS
Sbjct: 1860 TGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLS 1919
Query: 1970 AVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLP 2029
++ QV+C+Q+A+R L + + + P + IFITMNPGYAGR+ LP
Sbjct: 1920 VIAVQVKCVQDAIRAKKK----------AFNFLGEIIGLIPTVGIFITMNPGYAGRAELP 1969
Query: 2030 DNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFG 2089
+NLK LFR AM PD +LI ++ML ++GF A +LA K + + LC E LS Q HYD+G
Sbjct: 1970 ENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWG 2029
Query: 2090 LRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKL 2149
LRA+KSVLV AG++KR + E ++L++++ + +PK+
Sbjct: 2030 LRAIKSVLVVAGSLKRGDPSRA---------------------EDQVLMRALRDFNIPKI 2068
Query: 2150 VAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQ 2209
V +D+P+ L+ D+FP + R + +K+ E+ L D +V KV+Q
Sbjct: 2069 VTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDS------FVLKVVQ 2122
Query: 2210 LYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLD 2269
L ++ Q+ H + +VG +GSGKS + L K + L+ + VA +DPKA++ D L+G ++
Sbjct: 2123 LEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKR-KPVAVDLDPKAVTCDELFGIIN 2181
Query: 2270 PNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPN 2329
P TREW DGLF+ ++R + + +WI+ DGD+DP W+E+LN+V+DDNK+LTL +
Sbjct: 2182 PVTREWKDGLFSTIMRDLANITH---DGPKWIILDGDIDPMWIESLNTVMDDNKVLTLAS 2238
Query: 2330 GERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDE 2389
ER+ L +R++FE+ L+ AT ATVSR G+++ + L + + ++++ R +
Sbjct: 2239 NERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRK------ 2292
Query: 2390 GEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDL 2449
+Q + A +M + L T + F + I +
Sbjct: 2293 -------------------------VQSEKANLMILF--DKYLPTCLDKLRFGFKKITPV 2325
Query: 2450 TRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSG----D 2505
+ + ++ +L C + PD P ++ +L Y V+ W+ G D
Sbjct: 2326 PEITVIQTILYLLE--C--LLTEKTVPPDSPRELYEL------YFVFTCFWAFGGAMFQD 2375
Query: 2506 SRLKMRAELGEY-IRRITTVPLPTAPNIPIIDYEVSI-SGEWSPWQAKVPQIEVETHKVA 2563
+ R E ++ I T+ P+ I DY + + ++ PW KVP E++
Sbjct: 2376 QLVDYRVEFSKWWINEFKTIKFPSQGTI--FDYYIDPDTKKFLPWTDKVPSFELD----- 2428
Query: 2564 APDV-----VVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPD---- 2614
PDV +V T +T+R + + + P++L G G+GK++ + L +L
Sbjct: 2429 -PDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYL 2487
Query: 2615 MEVVGLNF--SSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMD 2672
++ V NF +SA +L K + P G K LV F D++N+P++D
Sbjct: 2488 VQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT--------KKLVYFIDDMNMPEVD 2539
Query: 2673 KYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVP 2732
KYGT + IRQ ++H +Y T + Q+V NP + G + R RH
Sbjct: 2540 KYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS--GSFTIDSRLQRHFC 2597
Query: 2733 VVYVDYPGPASLTQIYGTF---NRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDT- 2788
V V +PG +LT IY T + A + +++ + L AA + + F
Sbjct: 2598 VFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAI 2657
Query: 2789 QPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDE 2848
+ HY+++ R+++ +G+ + + P++ L+R+W HE R++ D++V+++++
Sbjct: 2658 KFHYVFNLRDLSNIFQGLLFSTAEVLKTPLD-LVRLWLHETERVYGDKMVDEKDQETLHR 2716
Query: 2849 NIDTVALKHFPNIDREKAMSRPILYSNWLS----KDYIPV-DQEELRDYVKARLKVFYEE 2903
K F ++ E ++P ++ ++ Y+PV D L + L + E
Sbjct: 2717 VTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEV 2776
Query: 2904 ELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKV 2963
+ LVLF + + H+ RI+RI P+G+ LL+GV G+GK +LSR A+++GL V+QI +
Sbjct: 2777 NAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITL 2836
Query: 2964 HRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEG 3023
+ Y D DL ++ KN F+M +S V + FL +N LLA+GE+PGLF
Sbjct: 2837 KKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFME 2896
Query: 3024 DEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSP 3083
DE +++ + + G M D+ E +K+F +V R L V+ +P L+ RA P
Sbjct: 2897 DEVENIISSMRPQVKSLG-MNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFP 2955
Query: 3084 ALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAI 3143
A+ N ++WF +W +AL V F + + +PV+ + +I
Sbjct: 2956 AVVNCTAIDWFHEWPEDALVSVSARFLEETE----------GIPVI----------KASI 2995
Query: 3144 VNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNV 3203
+VH T+++ + R TP+ +L+ I Y NL +KR+EL + L
Sbjct: 2996 SFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLEN 3055
Query: 3204 GLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQ 3263
GL K++ T QV++L+ L I+ EL+ KN +A+ ++ + + ++ K+K ++ + + +
Sbjct: 3056 GLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVK 3115
Query: 3264 LHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALES 3323
+ + + +KQ + + DL K EPA++ AQ A+ ++ K +L E++S +PP AV +
Sbjct: 3116 VEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAA 3175
Query: 3324 ICLLL---GESTTD--WKQIRSIIMR-ENFIPTIVNFSAEEISDAIREKMKKNYMSNPSY 3377
+ +L G+ D WK + ++ + + F+ ++ F E I +A + K Y NP++
Sbjct: 3176 VMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQGNPTF 3234
Query: 3378 NYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMI 3437
+ E + S A + W I + + ++ V P R L++ + + Q+K + ++ I
Sbjct: 3235 DPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKI 3294
Query: 3438 RDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFK 3497
+L A+++ + +E + + A + + L+ L++E RW ++ E F+
Sbjct: 3295 AELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFR 3354
Query: 3498 NQMSTIAGDCLLSAAFIAYAGYFDQQMRQNL----FTTWSHHLQQANIQFRTDIARTEYL 3553
+Q T+ GD LL +AF++Y GYF ++ R L + + H+L+ I + L
Sbjct: 3355 SQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLK-VPIPITNGLDPLSLL 3413
Query: 3554 SNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDR----KI 3609
++ + W LP+D + TENA +L R+PLI+D Q ++I N+Y+ ++
Sbjct: 3414 TDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRL 3473
Query: 3610 TRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQD 3668
+ S+LD +E A+ G+ LL++++ E+ DPVL+P+L R + G I +GD++
Sbjct: 3474 GQKSYLDV-----IEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGK--YIKIGDKE 3526
Query: 3669 IDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKR 3728
++ P F + L T+ + P++ ++ T +NF VTR L+ Q L V+ ERPD+++ +
Sbjct: 3527 VEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLK 3586
Query: 3729 SDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETD 3788
++L K Q EF++ L++LE SLL L+ G L D ++ LE K A+E+ KV E
Sbjct: 3587 ANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAK 3646
Query: 3789 IVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKG 3848
I ++ + Y P + S +YF + L +I+ +YQ+SL+ F ++ +
Sbjct: 3647 ITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANE 3706
Query: 3849 VTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKG-TVGEPTYDAEFQH 3907
V QR+ +T ++ + ARG+ +D + F LA++ + ++ + E
Sbjct: 3707 V---KQRVINLTDEITYSVYMYTARGLFERDKLIF---LAQVTFQVLSMKKELNPVELDF 3760
Query: 3908 FLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSSP 3966
LR AG + L + + LS + FK+L + ++ +++ ++S +P
Sbjct: 3761 LLR---FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAP 3817
Query: 3967 EQTV-PYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPL 4025
E+ + P W +T A+ +L +++ RPDR+ FV +G F+
Sbjct: 3818 EKEIFPKEWKNKT-------ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEF 3870
Query: 4026 DLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAE-----QNTQITSIAIGSAEGFNQA 4080
++ E P+T + PG D VE L + N ++ ++++G + A
Sbjct: 3871 SKSY---EESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEV-VA 3926
Query: 4081 DKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKL--HSLQPHACFRLFLTMEINPK----- 4133
+ A++ A + G WV+L+N+HL WL L+KKL +S H +R+F++ E P
Sbjct: 3927 ENALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHI 3986
Query: 4134 VPVNLLRAGRIFVFEPPPGVKANMLRTFS--SIPVSRICKSPNERARLYFLLAWFHAIIQ 4191
+P +L EPP G+ AN+ + + +C E + F L +FHA++
Sbjct: 3987 IPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVA 4046
Query: 4192 ERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSI 4251
ER ++ GW++ Y F DL + + + +L+ + K+PW L+ L + +
Sbjct: 4047 ERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE---------ANPKVPWDDLRYLFGEIM 4097
Query: 4252 YGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVEL 4311
YGG + +++D+RL T+L T + + LA Q+P + + + ++++
Sbjct: 4098 YGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLA------PGFQIPPNLDYKGYHEYIDE 4151
Query: 4312 LPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSD 4371
++P GL NAE LT + +L+MQ E TDS +
Sbjct: 4152 NLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKE---------------TDSGAG 4196
Query: 4372 GRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENI-KDPLFRFFEREVKMGAKLLQDVRQD 4430
+ + + L IP+T + + + K P +E + L ++R+
Sbjct: 4197 TGVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRS 4256
Query: 4431 LADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQ 4490
L ++ +G+ T + L L +P +W P+ M + W +D RI++L+
Sbjct: 4257 LKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELE 4316
Query: 4491 NISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQG 4550
+ A V L G F P++++TA Q +A+ N W L+++CL V VT
Sbjct: 4317 AWTTDFALPTT-------VWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNR 4369
Query: 4551 ATLDAC---SFGVTGLKLQGATCNNNKLSLSNA----ISTALPLTQLRWVKQTNTEKKAS 4603
+ A V GL ++GA + ++ A ++ A+P+ ++ + E K +
Sbjct: 4370 EDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETK-N 4428
Query: 4604 VVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVL 4643
+ PVY R + F + TKE + VA+L
Sbjct: 4429 IYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAVALL 4467
Score = 48.9 bits (115), Expect = 1e-04
Identities = 123/642 (19%), Positives = 257/642 (40%), Gaps = 68/642 (10%)
Query: 238 DPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQ-----EISFWLNLERALYRIQEKR 292
D L+ +++ + W +I+ V D A L E FW L I E+
Sbjct: 186 DNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQL 245
Query: 293 ESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATE--- 349
P+V ++IL+ K + + T + + L+ ND +K PL LL E
Sbjct: 246 NRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLK--PLRILLEEMEQAD 303
Query: 350 LDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKV----LGTRKLMHVA 405
+ + + + I T R++ I ++ +Q++++ L +++
Sbjct: 304 FTMLPTFIAKVLDTICFIWATSEYYNTPARII-VILQEFCNQIIEMTRTFLSPEEVLKGL 362
Query: 406 YEEFEKVMVACF-------EVFQTWDDEYEKLQVLLRDIVKRKREENLKMVW-RINPAHR 457
E E+V+ E++QT+D +++ +D E + + RIN +
Sbjct: 363 QGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQ 422
Query: 458 KLQARLDQMRKFRRQHEQLRAVIVRVLRPQVT-AVAQQNQGEVPEPQDMKVAEVLFDAAD 516
++Q ++++ K + +L + + +R + ++ + EV E + A+ +D D
Sbjct: 423 RIQT-IEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKV-FADCKYDPLD 480
Query: 517 ANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAK 576
++V GLD + A + + +DR I + D K
Sbjct: 481 PG---------DSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIK 531
Query: 577 NANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMS 636
++ ++ + L RP I + + +++ ++++ + Q S+ +
Sbjct: 532 SSAKLLYMCG---GLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIP 588
Query: 637 HV-RDLPPVSGSIIWAKQIDRQLTA---YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMK 692
+ +++PPV+G + W+ ++ +L ++K VE + G E + QK + + R
Sbjct: 589 LIHKNMPPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLR-- 646
Query: 693 LNTQEIFDDWARKVQQR---NLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKE 749
+ ++I+ W V Q NLG + +R N+ + VNF ++ + +E
Sbjct: 647 CHREKIYQQWVAGVDQDCHFNLG--------QPLILRDAASNL--IHVNFSKALVAVLRE 696
Query: 750 VRNLKWLGFRVPLAIVNKAH---QANQLY-PFAISLIESVRTYERTCEKVEERNTISLLV 805
V K+L F+ I + A N+ + F +L V Y + VE L+
Sbjct: 697 V---KYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIVGWYNEVMKAVE----FLLIK 749
Query: 806 AGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKV 847
+ L+ L++ L W + Y+Q + E + N Q ++
Sbjct: 750 SELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNRM 791
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 1365 bits (3534), Expect = 0.0
Identities = 990/3449 (28%), Positives = 1682/3449 (48%), Gaps = 316/3449 (9%)
Query: 1299 KAKEALELTDTGLLSGSEER--VQVAL----------EELQDLKGVWSELSKVWEQIDQM 1346
KA E LE + +L E +VAL +E++ LKG+W + V ID
Sbjct: 1284 KANEELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNW 1343
Query: 1347 KEQPWVSVQPRKLRQNLDAL-----LNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVI 1401
+ W + ++ L + ++ S +R + +Y ++ +K +
Sbjct: 1344 TKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAIT 1403
Query: 1402 ELKSEALKDRHWKQLMKRLHVNWVVSELT-LGQIWDVDLQKNEAIVKDVLLVAQGEMALE 1460
EL+S AL+DRHW QLMK + V ++++E T L + + L + E V+ ++ A E+ E
Sbjct: 1404 ELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTE 1463
Query: 1461 EFLKQIREVWNTYELDL-VNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEED 1519
+ + +I + W T + V+Y+ L++ + LF ++ + + + S Y + F E
Sbjct: 1464 KVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQ 1523
Query: 1520 ALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALM 1579
LSW++KLN + W++VQR W +LE IF S DI+ L + +RF + EF LM
Sbjct: 1524 VLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELM 1583
Query: 1580 KKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLE 1639
K +K V++ + L+ L L +KAL EYLE +R +FPRFYFV DLL+
Sbjct: 1584 FKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLD 1643
Query: 1640 IIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSV----VLGISSREGEEVMFKTPVSITEH 1695
I+ ++ H K+F ++ + ++ V +G+ S+E E V F+ H
Sbjct: 1644 ILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGH 1703
Query: 1696 PKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQ 1755
+ WL +E+ M+ T+ + E++ E + WI + AQ+ + S+Q
Sbjct: 1704 --VETWLLQLEQTMQETVRHSITEAIVAYEEKPREL---------WIFDFPAQVALTSSQ 1752
Query: 1756 IAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITEL 1815
I W+ +V A S + G + A L LN L +L E PP R+K+ + T
Sbjct: 1753 IWWTTDVGIAFSRLEEGYETA-LKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTID 1811
Query: 1816 VHQRDVTRSLIKSK--IDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYL 1873
VH RDV LI K + + ++F WLSQ+R ++ D + + + +A+F Y +EYL
Sbjct: 1812 VHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWE----DTQKHCFVNICDAQFQYFYEYL 1867
Query: 1874 GVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCD 1933
G +LV TPLTDRCY+T+TQ+L + G+P GPAGTGKTE+ K LG LG V VFNC
Sbjct: 1868 GNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCS 1927
Query: 1934 ETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKT 1993
E D++++G I+ GL Q GAWGCFDEFNR+ +LS V+ QV+ I +A+R
Sbjct: 1928 EQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKK------ 1981
Query: 1994 SAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVM 2053
L + + + P + IFITMNPGYAGR+ LP+NLK LFR AM PD +LI +++
Sbjct: 1982 ----RFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEIL 2037
Query: 2054 LYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKR 2113
L ++GF A LA K + + LC E LS Q HYD+GLRA+KSVLV AG++KR
Sbjct: 2038 LVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKR-------- 2089
Query: 2114 EKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRG 2173
G+ +N PE ++L++++ + +PK+V +DIP+ L+ D+FP + R
Sbjct: 2090 -----------GD--KNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRR 2136
Query: 2174 EMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMA 2233
+ +++ E+ L + ++ KV+QL ++ + H + +VG +G+GKS
Sbjct: 2137 RKLHFEQMVRQSTLELRLQPEES------FILKVVQLEELLAVRHSVFVVGNAGTGKSKI 2190
Query: 2234 WRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDG---------LFTHVL 2284
R L + ++ + V + ++PKA++ D L+G + TREW DG LF+ +L
Sbjct: 2191 LRTLNRTYVNMKQ-KPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSIL 2249
Query: 2285 RKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFE 2344
R + + +WIV DGD+DP W+E+LN+V+DDNK+LTL + ER++L P +R++FE
Sbjct: 2250 R---EQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFE 2306
Query: 2345 VQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDE 2404
+ L+ AT ATVSR G+++ + D+ +N ++A RRR
Sbjct: 2307 IHHLRSATPATVSRAGILYVNPQ----DLGWNPYVASW-----------IDRRR-----H 2346
Query: 2405 GEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQ 2464
E A+ + + + TS +T E + ++ + L L CL
Sbjct: 2347 QSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSL-VQTLCVL--LECL--------L 2395
Query: 2465 ACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSG----DSRLKMRAELGEYIRR 2520
NV D P ++ ++ Y V+A +W+ G D +A+ + ++
Sbjct: 2396 TPENVPS------DSPKEVYEV------YFVFACIWAFGGTLLQDQISDYQADFSRWWQK 2443
Query: 2521 -ITTVPLPTAPNIPIIDYEVSI-SGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHE 2578
+ V P+ I DY V + + PW K+ Q ++ V V+V T +T R
Sbjct: 2444 EMKAVKFPSQGTI--FDYYVDHKTKKLLPWADKIAQFTMDPD-VPLQTVLVHTTETARLR 2500
Query: 2579 ALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVG---LNFSSATTP--ELLLK 2633
+ L + KPL+L G G GKT+ + L +L + +V N+ + +T ++L K
Sbjct: 2501 YFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSEDYIVSRVPFNYYTTSTALQKILEK 2560
Query: 2634 TFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY 2693
+ + P G K L+ F D++N+P++D YGT + + IRQ +++G +Y
Sbjct: 2561 PLEKKAGHNYGPGG--------NKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWY 2612
Query: 2694 RTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYG---T 2750
++ Q+V NP G ++ R RH V ++P +L IYG +
Sbjct: 2613 DRQKVMLKEIHNCQYVACMNPMV--GSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFS 2670
Query: 2751 FNRAMLRLIPSLRTYAEPLTAAMVEFY-TMSQERFTQDTQPHYIYSPREMTRWVRGIFEA 2809
F+ PS+ L A + F+ TM + HYI++ R+++ +GI A
Sbjct: 2671 FHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFA 2730
Query: 2810 LRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSR 2869
P++ LI +W HE+ R++ D+L++ ++ + A K+F ID + +
Sbjct: 2731 SPECLKGPLD-LIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQ 2789
Query: 2870 PILYSNWLSKD----YIPV-DQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDR 2924
P++Y ++ + Y+PV D E L+ + L + E + LVLF + + HV RI R
Sbjct: 2790 PLIYCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISR 2849
Query: 2925 IFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSG 2984
I R PQG LL+GV G+GK +LSR A++ GL V+QI + Y ++ DL + R+G
Sbjct: 2850 ILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTG 2909
Query: 2985 CKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLML 3044
KN F++ ++ VLD FL +N LLA+GE+P LF ++ +++ G M+
Sbjct: 2910 AKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALG-MV 2968
Query: 3045 DSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQ 3104
DS E +K+F ++V L ++ +P L+ RA PA+ N ++WF W EAL
Sbjct: 2969 DSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVS 3028
Query: 3105 VGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKR 3164
V + F +E+ I P H+++I VH T+++ + R +
Sbjct: 3029 VSRRF-----IEETKGI--------------EPVHKDSISLFMAHVHTTVNEMSTRYYQN 3069
Query: 3165 GGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRI 3224
R TP+ +L+ I+ + NL +K++E+ E++ L G++K+K T QV +L+ L
Sbjct: 3070 ERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLAS 3129
Query: 3225 KSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDK 3284
+ EL+++N A + K+ ++ ++K ++ + ++ Q + KQ + DL K
Sbjct: 3130 QEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLK 3189
Query: 3285 VEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGE-----STTDWKQIR 3339
EPA++ A A+ ++ + +L E+++ NPP AV ++ +LL WK +
Sbjct: 3190 AEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAK 3249
Query: 3340 SIIMR-ENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIA 3398
+ + ++F+ ++N+ E I + + + ++Y+ +P +N ++ S A + W I
Sbjct: 3250 VFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVIN 3309
Query: 3399 QLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEA 3458
+ + ++ VEP R L + + +K + + + DL+ +++R + +E
Sbjct: 3310 IIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEK 3369
Query: 3459 QAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAG 3518
+ ++ + + L+K L A++ RW ++ ++F+ Q T+ GD LL+AAF++Y G
Sbjct: 3370 VRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVG 3429
Query: 3519 YFDQQMRQNLF-TTWSHHLQQ-ANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTEN 3576
F +Q RQ L W LQQ +I + L++ W LP+D + TEN
Sbjct: 3430 PFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTEN 3489
Query: 3577 AIMLKRFNRYPLIIDPSGQATEFIMNEY-KDRKITRTSFLDDAFRKNLESALRFGNPLLV 3635
A +L R+PL+IDP Q ++I N+Y D K+T F +E+AL FG+ +L+
Sbjct: 3490 AAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKVTHLG--QKGFLNAIETALAFGDVILI 3547
Query: 3636 QDVE-SYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCS 3694
+++E + DPVL+P+L R + G I +GD++ + + +F + L T+ + P+L +
Sbjct: 3548 ENLEETIDPVLDPLLGRNTIKKGK--YIRIGDKECEFNKNFRLILHTKLANPHYKPELQA 3605
Query: 3695 RVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALN 3754
+ T +NFTVT L++Q L EV+ ERPD+++ + L K Q +F++ L+ LE LL L+
Sbjct: 3606 QTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLS 3665
Query: 3755 EVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFT 3814
+G LDD ++ LE K AE+ KV E +++ + Y P++ S +YF
Sbjct: 3666 AAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFV 3725
Query: 3815 MESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARG 3874
+ L++I+ LYQ+SL+ F ++H + + V D R+SI+ + + F ++
Sbjct: 3726 INDLQKINPLYQFSLKAFNVLFHRAIEQADK---VEDMQGRISILMESITHAVFLYTSQA 3782
Query: 3875 MLHQDHITFAMLLA-RIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAE 3933
+ +D +TF +A +I L+ +P E LR + + LT +
Sbjct: 3783 LFEKDKLTFLSQMAFQILLRKKEIDP---LELDFLLR---FTVEHTHLSPVDFLTSQSWS 3836
Query: 3934 AVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSSPE-QTVPYLWSEETPATPIGQAIHRLL 3991
A+ ++ + F+ + V+ +Q+ W++S PE + +P W +++ I +L+
Sbjct: 3837 AIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKS-------LIQKLI 3889
Query: 3992 LIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDA 4051
L++A RPDR+ FV LG + + LDL E P TP+ PG DA
Sbjct: 3890 LLRAMRPDRMTYALRNFVEEKLGAKY--VERTRLDLVKAF-EESSPATPIFFILSPGVDA 3946
Query: 4052 SGHVEDLAAEQNTQITS-----IAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWL 4106
+E L I S +++G + A+ A+ A K G WV+L+NVHL WL
Sbjct: 3947 LKDLEILGKRLGFTIDSGKFHNVSLGQGQE-TVAEVALEKASKGGHWVILQNVHLVAKWL 4005
Query: 4107 MQLEKKLH--SLQPHACFRLFLTMEINPK-----VPVNLLRAGRIFVFEPPPGVKANM-- 4157
LEK L S H +R+F++ E P +P LL EPP G+ AN+
Sbjct: 4006 GTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHA 4065
Query: 4158 -LRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSAC 4216
L F IC E + F L +FHA + RLR+ P GWS+ Y F DL
Sbjct: 4066 ALYNFDQ-DTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICA 4124
Query: 4217 DTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTR 4276
+ +L+ + K+PW L+ L + +YGG + +++D++L +LE
Sbjct: 4125 SVLYNYLE---------ANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPS 4175
Query: 4277 SFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQG 4336
+ E LA P + + Q++E + ++P+ GL NAE LT
Sbjct: 4176 LTEDELMLA------PGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTS 4229
Query: 4337 VDMISKMLKMQMLE--DEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQT 4394
+ +L+MQ D+L + EK + + L +P+
Sbjct: 4230 NTLFRTLLEMQPRNALSGDELGQSTEEK-----------------VKNVLDDILEKLPEE 4272
Query: 4395 LSHLKRTVENI-KDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLIN 4453
+ + +N + P +E + L++++R L + +G+ + +
Sbjct: 4273 FNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSPAVEAQQF 4332
Query: 4454 ELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQL----QNISLAAASGGAKELKNIHV 4509
L +P +WS P+ + QW +D R ++L Q+++L A V
Sbjct: 4333 ALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAV-----------V 4381
Query: 4510 CLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTS----------QGATLDACSFG 4559
L G F P++++TA Q +A+ N W L++ L +VT +GA L
Sbjct: 4382 WLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLH----- 4436
Query: 4560 VTGLKLQGATCNNNKLSLSNA--ISTALPLTQLRWVKQTNTEKKASVVT--LPVYLNFTR 4615
GL ++GA + ++ A A P+ + + K T +++ + T PVY R
Sbjct: 4437 --GLFMEGARWDTQAGTIVEARLKELACPMPVI-FAKATPVDRQETKQTYECPVYRTKLR 4493
Query: 4616 A-DLIFTVDFEIATKEDPRSFYERGVAVL 4643
I+T F + ++E + GVA+L
Sbjct: 4494 GPSYIWT--FRLKSEEKTAKWVLAGVALL 4520
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 1355 bits (3508), Expect = 0.0
Identities = 964/3524 (27%), Positives = 1693/3524 (48%), Gaps = 288/3524 (8%)
Query: 1211 IDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQE-DRAVESRTTD---LLTDWEKTKP 1266
ID ++ A+ ++ R +Q ++ +LQ +E AVE D D++ P
Sbjct: 1296 IDKVDTLHYAWEKLLARAGE-VQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGP 1354
Query: 1267 VTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEEL 1326
+ L+P+EA L +++ +F + +E L T E + Q+ L
Sbjct: 1355 MASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNL--- 1411
Query: 1327 QDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFV 1386
L+ +++ + V E ++ + W V K+ L N+ + P L+ + ++ +
Sbjct: 1412 --LQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDL 1469
Query: 1387 QRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE--LTLGQIWDVDLQKNEA 1444
++++ + + L+ + S+A+ +RHW+++ + V L I + L K +
Sbjct: 1470 KKIIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKE 1529
Query: 1445 IVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWD---DLFNKVKEHI 1501
++D+ + A E +E+ LKQ+ W+ +++ + L+ D ++ +++ +
Sbjct: 1530 EIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSL 1589
Query: 1502 NSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLL 1561
+ ++ + Y F+ W L+ + + W+ VQ W+YLE +F G DI L
Sbjct: 1590 MLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG-DIAKQL 1648
Query: 1562 PVETQRFQSISTEFLALMKKVSKSPLVMDV-LNIQGVQRSLERLADLLGKIQKALGEYLE 1620
P E +RF +I ++ +M + + P V+ + + + + L L D L QK+L YLE
Sbjct: 1649 PKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLE 1708
Query: 1621 RERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNED-NSVVLGISSR 1679
++R FPRF+FV D LLEI+G + + +Q H +F + S+ +E +L ISS+
Sbjct: 1709 KKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSISSQ 1768
Query: 1680 EGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYI 1739
EGE + PV + ++ WL + +E + +L ++ ++ ++ G +
Sbjct: 1769 EGETIELDKPVMAEGNVEV--WLNSLLEESQSSLHLVIRQAAANIQETGFQLT------- 1819
Query: 1740 TWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLME 1799
++ + AQ+ +L Q+ W+ + E AL + D + LN L D +
Sbjct: 1820 EFLSSFPAQVGLLGIQMIWTRDSEEALRN--AKFDKKIMQKTNQAFLELLNTLIDVTTRD 1877
Query: 1800 QPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSI 1859
R K E LIT VHQRD+ L I + FEWL Q RFYF+ ++ I
Sbjct: 1878 LSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDS----DKMMI 1933
Query: 1860 QMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKAL 1919
+ + F Y E+LG D+LV TPLTDRCY+T+ QAL +GG+P GPAGTGKTE+ K +
Sbjct: 1934 HITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDM 1993
Query: 1920 GHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQ 1979
G LG++V+VFNC + DF+ +GRIF GL Q G+WGCFDEFNR++ +LS +QQ+ I
Sbjct: 1994 GRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIIL 2053
Query: 1980 EALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSL 2039
+EH K S T V ++P+ +F+TMNPGYAGR LP+NLK FRS+
Sbjct: 2054 TCKKEH------KKSFIFTD---GDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSV 2104
Query: 2040 AMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVS 2099
AM PDRQ+I +V L S GF VLA K +KLC+EQLS Q HYDFGLR + SVL +
Sbjct: 2105 AMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRT 2164
Query: 2100 AGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETM-VPKLVAEDIPLLF 2158
G KR A + + ++ V M + KL+ ED PL
Sbjct: 2165 LGAAKR----------------------ANPMDTESTIVMRVLRDMNLSKLIDEDEPLFL 2202
Query: 2159 SLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINH 2218
SL+ D+FP + + L + + +E L W KV+QL++ ++ H
Sbjct: 2203 SLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPP------WKLKVIQLFETQRVRH 2256
Query: 2219 GLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDG 2278
G+M +GPSG+GK+ L++A+ G ++PKAI+ ++G LD T +WTDG
Sbjct: 2257 GMMTLGPSGAGKTTCIHTLMRAMTDC-GKPHREMRMNPKAITAPQMFGRLDVATNDWTDG 2315
Query: 2279 LFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPN 2338
+F+ + RK + + +GE WI+ DG VD W+ENLNSVLDDNK LTL NG+R+ + PN
Sbjct: 2316 IFSTLWRKTLRAKKGE---HIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPN 2372
Query: 2339 VRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRR 2398
+I+FE ++ A+ ATVSR GMV+ S +L I FL ++R
Sbjct: 2373 CKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFL----------------KKR 2416
Query: 2399 KGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTR-LRCLGS 2457
+E A + Q+ ++ + + N LE+ ++ +T+ + L
Sbjct: 2417 SPQE------AEILRQLYTESFPDLYRFCIQN------LEYKMEVLEAFVITQSINMLQG 2464
Query: 2458 LFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEY 2517
L + Q E + ++ R V+A+LWS L R L +
Sbjct: 2465 LIPLKEQGG-----------------EVSQAHLGRLFVFALLWSAGAALELDGRRRLELW 2507
Query: 2518 IRRITT----VPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAA-PDVVVPTL 2572
+R T +P P P DY V+ G W+ W + + + ++VP +
Sbjct: 2508 LRSRPTGTLELPPPAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNV 2567
Query: 2573 DTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRAL-PDMEVV-GLNFSSATTPEL 2630
D VR + L+ T + K ++L G G+ KT+ + + P+ ++ LNFSSATTP +
Sbjct: 2568 DNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLM 2627
Query: 2631 LLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHG 2690
+T + Y + R G P GK + +F D++N+P ++++G Q +RQ++E
Sbjct: 2628 FQRTIESYVDKRM---GTTYGP-PAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQN 2683
Query: 2691 GFYRTSDQ-TWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYG 2749
GFY + + IQF+ A P GR + R R + P AS+ +I+G
Sbjct: 2684 GFYNLEKPGEFTSIVDIQFLAAMIHPGG-GRNDIPQRLKRQFSIFNCTLPSEASVDKIFG 2742
Query: 2750 TFN-------RAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRW 2802
R + T PLT + + + + HY+++ R+++R
Sbjct: 2743 VIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKM--LPTPAKFHYVFNLRDLSRV 2800
Query: 2803 VRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNID 2862
+G+ + P + L+++W HE R+ DR + W D+ + ++ + F
Sbjct: 2801 WQGMLNTTSEVIKEPND-LLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEK 2859
Query: 2863 R-------------------EKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVF--- 2900
+ E A K Y P+ E ++K RL +F
Sbjct: 2860 KLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEPI---ESFSHLKERLNMFLQL 2916
Query: 2901 YEEEL---DVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLS 2957
Y E + + +V F + + H+++I R+ R PQG+ LL+GV G+GK +L+R +++ G
Sbjct: 2917 YNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYV 2976
Query: 2958 VYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEV 3017
+QI + R Y + EDL+ + R +G + + I FI ++ + D FLE MN +L++GEV
Sbjct: 2977 SFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEV 3036
Query: 3018 PGLFEGDEYATLMTQCKEGAQKE-GLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLK 3076
LF DE + + +KE L ++E L+ +F S+V +NLH+V +P E +
Sbjct: 3037 SNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFR 3096
Query: 3077 DRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQP 3136
+RA PAL + C ++WF W +AL V + F + D++ I + + +
Sbjct: 3097 NRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCM------- 3149
Query: 3137 PSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEE 3196
S ++ + CV Q R R+ +TP+ YL FI Y ++ EK E+
Sbjct: 3150 GSFQDGVAEKCVDYFQ-----------RFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRT 3198
Query: 3197 QQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVM 3256
+N GL K+KE + V L ++L K +EL+V N A+ LK++ Q AEK K
Sbjct: 3199 LANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAE 3258
Query: 3257 SQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAA 3316
Q+++++ + I+ + +E L+ +PA+ EA+ A+++I+ + VR++ PP
Sbjct: 3259 VQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHL 3318
Query: 3317 VKLALESICLL-----------LGESTT--DWKQIRSIIMRENFIPTIVNFSAEEISDAI 3363
+ ++ + LL L +S T W++ ++ NF+ + F + I++ +
Sbjct: 3319 IMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEV 3378
Query: 3364 REKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDA 3423
E + Y P YN E R + W A ++ + K V PL+ L E+
Sbjct: 3379 IEFLSP-YFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRH 3437
Query: 3424 KDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLS 3483
Q + + + D +A + + EY ++E Q + D K+ ++ L+ L+
Sbjct: 3438 LLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLA 3497
Query: 3484 AERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQF 3543
E+ERW + S+ F Q + GD LL+ AF++Y+G F+Q+ R L W ++ I F
Sbjct: 3498 GEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPF 3557
Query: 3544 RTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNE 3603
++ +E L +A W LP DDL +N I++ + +RYPL+IDP Q +I N+
Sbjct: 3558 GKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNK 3617
Query: 3604 YKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLI 3662
++ TS FR +LE +L G PLL++DV E DP L+ VL R +TG +
Sbjct: 3618 ESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKV 3677
Query: 3663 TLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERP 3722
+GD+++D+ F ++++T+ P + P++ +R + ++FTVT L+ Q L V+ E+
Sbjct: 3678 KVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQ 3737
Query: 3723 DVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTR 3782
+++++R+ L++ + R+++LE +LL L +G +++D+++I L N KR A EVT+
Sbjct: 3738 ELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQ 3797
Query: 3783 KVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYE 3842
K+E + ++ + ++Y P++T S +YF + ++ ++ +YQ SL+ FL ++ L
Sbjct: 3798 KLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLAR 3857
Query: 3843 NPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYD 3902
+ +T ++R++ I + + + ARG L+++H LL +K+ ++
Sbjct: 3858 SVK-SPIT--SKRIANIIEHMTYEVYKYAARG-LYEEHKFLFTLLLTLKIDIQRNRVKHE 3913
Query: 3903 AEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEA-VVRLSCLPAFKDLIAKVQADEQ-FGIW 3960
EF ++G + P+ ++ +V LS L F D++ ++ +E+ + IW
Sbjct: 3914 -EFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIW 3972
Query: 3961 LDSSSP-EQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMS 4019
D +P E+ +P + + RLLLI+++ PDR +A A ++ ++GE +
Sbjct: 3973 FDKENPEEEPLPNAYDKSL------DCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAE 4026
Query: 4020 IMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQ 4079
+ L+ T E P TP++ G D + + L + +++G + +
Sbjct: 4027 GVILDLEKT---WEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVH- 4082
Query: 4080 ADKAINTAVKSGRWVMLKNVHLAPGWLMQL-EKKLHSLQPHACFRLFLTMEINPKVPVNL 4138
A K + + +G W +L+N HL ++ +L + + + H FRL++T E + + P+ L
Sbjct: 4083 ARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPITL 4142
Query: 4139 LRAGRIFVFEPPPGVKANMLRTFSSIPVSRI-CKSPNERARLYFLLAWFHAIIQERLRYA 4197
L+ F +PP G++A + RT+S + + S ++ + + +A+ H+ +QER ++
Sbjct: 4143 LQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRKFG 4202
Query: 4198 PLGWSKKYEFGESDLRSACDTVDTWLD--DTAKGRQNISPDKIPWSALKTLMAQSIYGGR 4255
LGW+ YEF ++D + + LD D KG + W+ ++ ++ + YGGR
Sbjct: 4203 ALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKG--------VSWTTIRYMIGEIQYGGR 4254
Query: 4256 VDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDT 4315
V +++D+RLLNTF + F+ F +F ++ +P + ++Q+++ LP
Sbjct: 4255 VTDDYDKRLLNTFAKVWFSENMFGPDFSF------YQGYNIPKCSTVDNYLQYIQSLPAY 4308
Query: 4316 QTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPA 4375
+P GL NA+ + D++ +L +Q D++ G
Sbjct: 4309 DSPEVFGLHPNADITYQSKLAKDVLDTILGIQ-----------------PKDTSGGGDET 4351
Query: 4376 WMRTLHTTASNWLHLIPQTL--SHLKRTVENIK--DPLFRFFEREVKMGAKLLQDVRQDL 4431
+ A + L +P +K ++ + P+ F +E+ ++L VR L
Sbjct: 4352 REAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTL 4411
Query: 4432 ADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSD-----FSERI 4486
++ +G + LR ++ + +P W W+S F+E I
Sbjct: 4412 TELKLAIDGTIIMSENLRDALDCMFDARIPAWWKK---------ASWISSTLGFWFTELI 4462
Query: 4487 KQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQAN-SWSLEELCLEVNV 4545
++ + +G + + G F P+ ++TA RQ + +AN W+L+ + L V
Sbjct: 4463 ERNSQFTSWVFNG-----RPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEV 4517
Query: 4546 TTSQGATLDAC---SFGVTGLKLQGATCNNNKLSLSNAISTAL--PLTQLRWVKQTNTEK 4600
T + A V GL L+GA + + L + L + +R + NT +
Sbjct: 4518 TKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYAENNTLR 4577
Query: 4601 KASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLC 4644
+ P+Y R DL + ++ T + P + RGVA+LC
Sbjct: 4578 DPRFYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALLC 4621
Score = 51.6 bits (122), Expect = 2e-05
Identities = 124/650 (19%), Positives = 255/650 (39%), Gaps = 79/650 (12%)
Query: 230 TDFGDKVEDPTFLNQLQSGVNRWIREIQKV----TKLDRDPASGTALQEISFWLNLERAL 285
TD+ +P L +++ + WI++ ++V +L ++ E+ W
Sbjct: 238 TDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSKF 297
Query: 286 YRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFP-LNDL 344
+ E+ +SP+V L +L K + D + A D + D
Sbjct: 298 NYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDP 357
Query: 345 LSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHV 404
L +++ + A+ + ++ I Y I E I+ S +KV T +++
Sbjct: 358 LYSSDPLSMMDAIPTLINAIKMI----YSISHYYNTSEKIT----SLFVKV--TNQIISA 407
Query: 405 AYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENL-----KMVWRINPAHRKL 459
K + W+ + ++ + +K K+E L K + NP ++
Sbjct: 408 C-----KAYITNNGTASIWNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQF 462
Query: 460 Q-ARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADAN 518
+ + KF H +L +I + +V Q + E E K ++
Sbjct: 463 DFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIV------- 515
Query: 519 AIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNA 578
A KE + LD K ++ + + ++ + + + + +N
Sbjct: 516 -------ATIKKKEYNFLDQRKMD---FDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNT 565
Query: 579 NEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKF-KVQYPQSQACKMSH 637
N+ R+ +F L + P++ G +YQ +++ DI+ + + K +Y A
Sbjct: 566 NQALRMLKKFERLNI-PNL-GIDDKYQL-ILENYGADIDMISKLYTKQKYDPPLA----- 617
Query: 638 VRDLPPVSGSIIWAKQIDRQLTAYMKRVED---VLGKGWENHVEGQKLKQDGDSFRMKLN 694
R+ PP++G I+WA+Q+ ++ M+ + VL + ++ ++ L
Sbjct: 618 -RNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPI----IRSYNRMAKVLLE 672
Query: 695 TQEIFD-DWARKVQQRNLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNL 753
+ +F W R++++ ++G+ + + +L VNF P+I+ L +E +
Sbjct: 673 FEVLFHRAWLRQIEEIHVGLEASLLV--------KAPGTGELFVNFDPQILILFRETECM 724
Query: 754 KWLGFRV-PLAIVNKAHQANQLYPFAISLIE-SVRTYERTCEKVEERNTISLLVAGLKKE 811
+G V PLA Q Y S ++ + Y+R K+ L+V L K
Sbjct: 725 AQMGLEVSPLA--TSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAA-IEQLIVPHLAKV 781
Query: 812 VQALIAEGIALVWESYKLDPYVQRLAETVFNFQ---EKVDDLLIIEEKID 858
+AL AL W S ++ Y++ + + + ++V+DL IE +ID
Sbjct: 782 DEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDL--IEFRID 829
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1344 bits (3479), Expect = 0.0
Identities = 950/3423 (27%), Positives = 1677/3423 (48%), Gaps = 299/3423 (8%)
Query: 1317 ERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPAR 1376
++++ E++ LK +W + V I+ K W + ++ + ++S
Sbjct: 1263 KQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKE 1322
Query: 1377 LRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIW 1435
++ + ++ + +K + V EL++ A+++RHW+QLM+ V + +SE TL +
Sbjct: 1323 MKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLL 1382
Query: 1436 DVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNY-QNKCRLIRGWDDLF 1494
++L E V++++ A E +E+ LK + W+ E + + +++ + L
Sbjct: 1383 QLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLV 1442
Query: 1495 NKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGS 1554
++++ + + +S Y F ++ SW+ KL+ ++ +W +VQR W +LE IF GS
Sbjct: 1443 ETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGS 1502
Query: 1555 ADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKA 1614
DI+ LP ++QRF I+ EF ALM+ K+P V++ + G+ LE L L +KA
Sbjct: 1503 EDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKA 1562
Query: 1615 LGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS--- 1671
L EYLE +R +FPRFYFV DLL+I+ N + ++ +H K+F + + D S
Sbjct: 1563 LAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKP 1622
Query: 1672 --VVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGK 1729
V LG+ S+E E ++F ++ ++ WL V M TL + E+V
Sbjct: 1623 LKVGLGMYSKEDEYMVFDQECDLSGQVEV--WLNRVLDRMCSTLRHEIPEAV-------- 1672
Query: 1730 ATSIDPNTYITWIDKYQAQLVV-LSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVT 1788
+T+ +K + Q ++ AQI W+ V A + + G + A +
Sbjct: 1673 ---------VTYEEKPREQWILDYPAQIWWTTEVGLAFARLEEGYENA-IRDYNKKQISQ 1722
Query: 1789 LNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDP 1848
LNVL ++ R K+ + T VH RDV +I ++++++F W +Q+R +D
Sbjct: 1723 LNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDE 1779
Query: 1849 KQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPA 1908
++ + +A+ Y +EYLG +LV TPLTDRCY+T+TQ+L +GG+P GPA
Sbjct: 1780 EKRHCFANI----CDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPA 1835
Query: 1909 GTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERML 1968
GTGKTE+ K LG LG V VFNC E D+++ G I+ GL Q GAWGCFDEFNR+ +L
Sbjct: 1836 GTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVL 1895
Query: 1969 SAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNL 2028
S ++ QV+C+Q+A+R L + + + P + IFITMNPGYAGR+ L
Sbjct: 1896 SVIAVQVKCVQDAIRAKKK----------AFNFLGEIIGLIPTVGIFITMNPGYAGRAEL 1945
Query: 2029 PDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDF 2088
P+NLK LFR AM PD +LI ++ML ++GF A +LA K + + LC E LS Q HYD+
Sbjct: 1946 PENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDW 2005
Query: 2089 GLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPK 2148
GLRA+KSVLV AG++KR + E ++L++++ + +PK
Sbjct: 2006 GLRAIKSVLVVAGSLKRGDPSRA---------------------EDQVLMRALRDFNIPK 2044
Query: 2149 LVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVL 2208
+V +D+P+ L+ D+FP + R + +K+ E+ L D +V KV+
Sbjct: 2045 IVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDS------FVLKVV 2098
Query: 2209 QLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTL 2268
QL ++ Q+ H + +VG +GSGKS + L K + L+ + VA +DPKA++ D L+G +
Sbjct: 2099 QLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKR-KPVAVDLDPKAVTCDELFGII 2157
Query: 2269 DPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLP 2328
+P TREW DGLF+ ++R + + +WI+ DGD+DP W+E+LN+V+DDNK+LTL
Sbjct: 2158 NPVTREWKDGLFSTIMRDLANITH---DGPKWIILDGDIDPMWIESLNTVMDDNKVLTLA 2214
Query: 2329 NGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLD 2388
+ ER+ L +R++FE+ L+ AT ATVSR G+++ + L + + ++++ R +
Sbjct: 2215 SNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRK----- 2269
Query: 2389 EGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMD 2448
+Q + A +M + L T + F + I
Sbjct: 2270 --------------------------VQSEKANLMILF--DKYLPTCLDKLRFGFKKITP 2301
Query: 2449 LTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSG---- 2504
+ + + ++ +L C + PD P ++ +L Y V+ W+ G
Sbjct: 2302 VPEITVIQTILYLLE--C--LLTEKTVPPDSPRELYEL------YFVFTCFWAFGGAMFQ 2351
Query: 2505 DSRLKMRAELGEY-IRRITTVPLPTAPNIPIIDYEVSI-SGEWSPWQAKVPQIEVETHKV 2562
D + R E ++ I T+ P+ I DY + + ++ PW KVP E++
Sbjct: 2352 DQLVDYRVEFSKWWINEFKTIKFPSQGTI--FDYYIDPDTKKFLPWTDKVPSFELD---- 2405
Query: 2563 AAPDV-----VVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPD--- 2614
PDV +V T +T+R + + + P++L G G+GK++ + L +L
Sbjct: 2406 --PDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNY 2463
Query: 2615 -MEVVGLNF--SSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDM 2671
++ V NF +SA +L K + P G K LV F D++N+P++
Sbjct: 2464 LVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT--------KKLVYFIDDMNMPEV 2515
Query: 2672 DKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHV 2731
DKYGT + IRQ ++H +Y T + Q+V NP + G + R RH
Sbjct: 2516 DKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS--GSFTIDSRLQRHF 2573
Query: 2732 PVVYVDYPGPASLTQIYGTF---NRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDT 2788
V V +PG +LT IY T + A + +++ + L AA + + F
Sbjct: 2574 CVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTA 2633
Query: 2789 -QPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTD 2847
+ HY+++ R+++ +G+ + + P++ L+R+W HE R++ D++V+++++
Sbjct: 2634 IKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLD-LVRLWLHETERVYGDKMVDEKDQETLH 2692
Query: 2848 ENIDTVALKHFPNIDREKAMSRPILYSNWLS----KDYIPV-DQEELRDYVKARLKVFYE 2902
K F ++ E ++P ++ ++ Y+PV D L + L + E
Sbjct: 2693 RVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNE 2752
Query: 2903 EELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIK 2962
+ LVLF + + H+ RI+RI P+G+ LL+GV G+GK +LSR A+++GL V+QI
Sbjct: 2753 VNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQIT 2812
Query: 2963 VHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFE 3022
+ + Y D DL ++ KN F+M +S V + FL +N LLA+GE+PGLF
Sbjct: 2813 LKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFM 2872
Query: 3023 GDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATS 3082
DE +++ + + G M D+ E +K+F +V R L V+ +P L+ RA
Sbjct: 2873 EDEVENIISSMRPQVKSLG-MNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKF 2931
Query: 3083 PALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREA 3142
PA+ N ++WF +W +AL V F LE+ I P + +
Sbjct: 2932 PAVVNCTAIDWFHEWPEDALVSVSARF-----LEETEGI--------------PWEVKAS 2972
Query: 3143 IVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLN 3202
I +VH T+++ + R TP+ +L+ I Y NL +KR+EL + L
Sbjct: 2973 ISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLE 3032
Query: 3203 VGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQE 3262
GL K++ T QV++L+ L I+ EL+ KN +A+ ++ + + ++ K+K ++ + +
Sbjct: 3033 NGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEV 3092
Query: 3263 QLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALE 3322
++ + + +KQ + + DL K EPA++ AQ A+ ++ K +L E++S +PP AV
Sbjct: 3093 KVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTA 3152
Query: 3323 SICLLL---GESTTD--WKQIRSIIMR-ENFIPTIVNFSAEEISDAIREKMKKNYMSNPS 3376
++ +L G+ D WK + ++ + + F+ ++ F E I +A + K Y NP+
Sbjct: 3153 AVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQGNPT 3211
Query: 3377 YNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQM 3436
++ E + S A + W I + + ++ V P R L++ + + Q+K + ++
Sbjct: 3212 FDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNK 3271
Query: 3437 IRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETF 3496
I +L A+++ + +E + + A + + L+ L++E RW ++ E F
Sbjct: 3272 IAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENF 3331
Query: 3497 KNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNL----FTTWSHHLQQANIQFRTDIARTEY 3552
++Q T+ GD LL +AF++Y GYF ++ R L + + H+L+ I +
Sbjct: 3332 RSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLK-VPIPITNGLDPLSL 3390
Query: 3553 LSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDR----K 3608
L++ + W LP+D + TENA +L R+PLI+D Q ++I N+Y+ +
Sbjct: 3391 LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIR 3450
Query: 3609 ITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQ 3667
+ + S+LD +E A+ G+ LL++++ E+ DPVL+P+L R + G I +GD+
Sbjct: 3451 LGQKSYLDV-----IEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGK--YIKIGDK 3503
Query: 3668 DIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEK 3727
+++ P F + L T+ + P++ ++ T +NF VTR L+ Q L V+ ERPD+++
Sbjct: 3504 EVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQL 3563
Query: 3728 RSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEET 3787
+++L K Q EF++ L++LE SLL L+ G L D ++ LE K A+E+ KV E
Sbjct: 3564 KANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEA 3623
Query: 3788 DIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLK 3847
I ++ + Y P + S +YF + L +I+ +YQ+SL+ F ++ +
Sbjct: 3624 KITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPAN 3683
Query: 3848 GVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKG-TVGEPTYDAEFQ 3906
V QR+ +T ++ + ARG+ +D + F LA++ + ++ + E
Sbjct: 3684 EV---KQRVINLTDEITYSVYMYTARGLFERDKLIF---LAQVTFQVLSMKKELNPVELD 3737
Query: 3907 HFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSS 3965
LR AG + L + + LS + FK+L + ++ +++ ++S +
Sbjct: 3738 FLLR---FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEA 3794
Query: 3966 PEQTV-PYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQP 4024
PE+ + P W +T A+ +L +++ RPDR+ FV +G F+
Sbjct: 3795 PEKEIFPKEWKNKT-------ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVE 3847
Query: 4025 LDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAE-----QNTQITSIAIGSAEGFNQ 4079
++ E P+T + PG D VE L + N ++ ++++G +
Sbjct: 3848 FSKSY---EESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEV-V 3903
Query: 4080 ADKAINTAVKSGRWVML--------KNVHLAPGWLMQLEKKL--HSLQPHACFRLFLTME 4129
A+ A++ A + G WV+L +N+HL WL L+KKL +S H +R+F++ E
Sbjct: 3904 AENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAE 3963
Query: 4130 INPK-----VPVNLLRAGRIFVFEPPPGVKANMLRTFS--SIPVSRICKSPNERARLYFL 4182
P +P +L EPP G+ AN+ + + +C E + F
Sbjct: 3964 PAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFA 4023
Query: 4183 LAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSA 4242
L +FHA++ ER ++ GW++ Y F DL + + + +L+ + K+PW
Sbjct: 4024 LCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE---------ANPKVPWDD 4074
Query: 4243 LKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRR 4302
L+ L + +YGG + +++D+RL T+L T + + LA Q+P +
Sbjct: 4075 LRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLA------PGFQIPPNLDY 4128
Query: 4303 EEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDED--------- 4353
+ + ++++ ++P GL NAE LT + +L+MQ E +
Sbjct: 4129 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 4188
Query: 4354 ----DLAYAETEKKTR-TDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENI-KD 4407
L +E+K + G P + + L IP+T + + + K
Sbjct: 4189 EKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKT 4248
Query: 4408 PLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHY 4467
P +E + L ++R+ L ++ +G+ T + L L +P +W
Sbjct: 4249 PYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVAR 4308
Query: 4468 TVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQY 4527
P+ M + W +D RI++L+ + A V L G F P++++TA Q
Sbjct: 4309 AYPSMMGLAAWYADLLLRIRELEAWTTDFALPTT-------VWLAGFFNPQSFLTAIMQS 4361
Query: 4528 VAQANSWSLEELCLEVNVTTSQGATLDAC---SFGVTGLKLQGATCNNNKLSLSNA---- 4580
+A+ N W L+++CL V VT + A V GL ++GA + ++ A
Sbjct: 4362 MARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKE 4421
Query: 4581 ISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGV 4640
++ A+P+ ++ + E K ++ PVY R + F + TKE + V
Sbjct: 4422 LTPAMPVIFIKAIPVDRMETK-NIYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAV 4479
Query: 4641 AVL 4643
A+L
Sbjct: 4480 ALL 4482
Score = 48.1 bits (113), Expect = 2e-04
Identities = 116/640 (18%), Positives = 252/640 (39%), Gaps = 73/640 (11%)
Query: 238 DPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQ-----EISFWLNLERALYRIQEKR 292
D L+ +++ + W +I+ V D A L E FW L I E+
Sbjct: 186 DNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDTRLLNLKCIHEQL 245
Query: 293 ESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATE--- 349
P+V ++IL+ K + + T + + L+ ND +K PL LL E
Sbjct: 246 NRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLK--PLRILLEEMEQAD 303
Query: 350 LDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKV----LGTRKLMHVA 405
+ + + + I T R++ I ++ +Q++++ L +++
Sbjct: 304 FTMLPTFIAKVLDTICFIWATSEYYNTPARII-VILQEFCNQIIEMTRTFLSPEEVLKGL 362
Query: 406 YEEFEKVMVACF-------EVFQTWDDEYEKLQVLLRDIVKRKREENLKMVW-RINPAHR 457
E E+V+ E++QT+D +++ +D E + + RIN +
Sbjct: 363 QGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQ 422
Query: 458 KLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADA 517
++Q ++++ K + +L + + +R + G + +V E++ AD
Sbjct: 423 RIQT-IEELYKTAIEFLKLEKIELGGVRGNLL-------GSLVTRIYDEVFELVKVFADC 474
Query: 518 NAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKN 577
+ D LD + A + + +DR I + D K+
Sbjct: 475 --------------KYDPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKS 520
Query: 578 ANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSH 637
+ ++ + L RP I + + +++ ++++ + Q S+ +
Sbjct: 521 SAKLLYMCG---GLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPL 577
Query: 638 V-RDLPPVSGSIIWAKQIDRQLTA---YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKL 693
+ +++PPV+G + W+ ++ +L ++K VE + G E + QK + + R
Sbjct: 578 IHKNMPPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLR--C 635
Query: 694 NTQEIFDDWARKVQQR---NLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEV 750
+ ++I+ W V Q NLG + +R N+ + VNF ++ + +EV
Sbjct: 636 HREKIYQQWVAGVDQDCHFNLG--------QPLILRDAASNL--IHVNFSKALVAVLREV 685
Query: 751 RNLKWLGFRVPLAIVNKAH---QANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAG 807
K+L F+ I + A N+ + + +E + + + + + L+ +
Sbjct: 686 ---KYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIVGWYNEIKTIVKAVEFLLIKSE 742
Query: 808 LKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKV 847
L+ L++ L W + Y+Q + E + N Q ++
Sbjct: 743 LEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNRM 782
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1344 bits (3478), Expect = 0.0
Identities = 950/3423 (27%), Positives = 1677/3423 (48%), Gaps = 299/3423 (8%)
Query: 1317 ERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPAR 1376
++++ E++ LK +W + V I+ K W + ++ + ++S
Sbjct: 1263 KQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKE 1322
Query: 1377 LRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIW 1435
++ + ++ + +K + V EL++ A+++RHW+QLM+ V + +SE TL +
Sbjct: 1323 MKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLL 1382
Query: 1436 DVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNY-QNKCRLIRGWDDLF 1494
++L E V++++ A E +E+ LK + W+ E + + +++ + L
Sbjct: 1383 QLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLV 1442
Query: 1495 NKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGS 1554
++++ + + +S Y F ++ SW+ KL+ ++ +W +VQR W +LE IF GS
Sbjct: 1443 ETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGS 1502
Query: 1555 ADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKA 1614
DI+ LP ++QRF I+ EF ALM+ K+P V++ + G+ LE L L +KA
Sbjct: 1503 EDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKA 1562
Query: 1615 LGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS--- 1671
L EYLE +R +FPRFYFV DLL+I+ N + ++ +H K+F + + D S
Sbjct: 1563 LAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKP 1622
Query: 1672 --VVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGK 1729
V LG+ S+E E ++F ++ ++ WL V M TL + E+V
Sbjct: 1623 LKVGLGMYSKEDEYMVFDQECDLSGQVEV--WLNRVLDRMCSTLRHEIPEAV-------- 1672
Query: 1730 ATSIDPNTYITWIDKYQAQLVV-LSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVT 1788
+T+ +K + Q ++ AQI W+ V A + + G + A +
Sbjct: 1673 ---------VTYEEKPREQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQIS-Q 1722
Query: 1789 LNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDP 1848
LNVL ++ R K+ + T VH RDV +I ++++++F W +Q+R +D
Sbjct: 1723 LNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDE 1779
Query: 1849 KQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPA 1908
++ + +A+ Y +EYLG +LV TPLTDRCY+T+TQ+L +GG+P GPA
Sbjct: 1780 EKRHCFANI----CDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPA 1835
Query: 1909 GTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERML 1968
GTGKTE+ K LG LG V VFNC E D+++ G I+ GL Q GAWGCFDEFNR+ +L
Sbjct: 1836 GTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVL 1895
Query: 1969 SAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNL 2028
S ++ QV+C+Q+A+R L + + + P + IFITMNPGYAGR+ L
Sbjct: 1896 SVIAVQVKCVQDAIRAKKK----------AFNFLGEIIGLIPTVGIFITMNPGYAGRAEL 1945
Query: 2029 PDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDF 2088
P+NLK LFR AM PD +LI ++ML ++GF A +LA K + + LC E LS Q HYD+
Sbjct: 1946 PENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDW 2005
Query: 2089 GLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPK 2148
GLRA+KSVLV AG++KR + E ++L++++ + +PK
Sbjct: 2006 GLRAIKSVLVVAGSLKRGDPSRA---------------------EDQVLMRALRDFNIPK 2044
Query: 2149 LVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVL 2208
+V +D+P+ L+ D+FP + R + +K+ E+ L D +V KV+
Sbjct: 2045 IVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDS------FVLKVV 2098
Query: 2209 QLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTL 2268
QL ++ Q+ H + +VG +GSGKS + L K + L+ + VA +DPKA++ D L+G +
Sbjct: 2099 QLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKR-KPVAVDLDPKAVTCDELFGII 2157
Query: 2269 DPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLP 2328
+P TREW DGLF+ ++R + + +WI+ DGD+DP W+E+LN+V+DDNK+LTL
Sbjct: 2158 NPVTREWKDGLFSTIMRDLANITH---DGPKWIILDGDIDPMWIESLNTVMDDNKVLTLA 2214
Query: 2329 NGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLD 2388
+ ER+ L +R++FE+ L+ AT ATVSR G+++ + L + + ++++ R +
Sbjct: 2215 SNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRK----- 2269
Query: 2389 EGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMD 2448
+Q + A +M + L T + F + I
Sbjct: 2270 --------------------------VQSEKANLMILF--DKYLPTCLDKLRFGFKKITP 2301
Query: 2449 LTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSG---- 2504
+ + + ++ +L C + PD P ++ +L Y V+ W+ G
Sbjct: 2302 VPEITVIQTILYLLE--C--LLTEKTVPPDSPRELYEL------YFVFTCFWAFGGAMFQ 2351
Query: 2505 DSRLKMRAELGEY-IRRITTVPLPTAPNIPIIDYEVSI-SGEWSPWQAKVPQIEVETHKV 2562
D + R E ++ I T+ P+ I DY + + ++ PW KVP E++
Sbjct: 2352 DQLVDYRVEFSKWWINEFKTIKFPSQGTI--FDYYIDPDTKKFLPWTDKVPSFELD---- 2405
Query: 2563 AAPDV-----VVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPD--- 2614
PDV +V T +T+R + + + P++L G G+GK++ + L +L
Sbjct: 2406 --PDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNY 2463
Query: 2615 -MEVVGLNF--SSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDM 2671
++ V NF +SA +L K + P G K LV F D++N+P++
Sbjct: 2464 LVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT--------KKLVYFIDDMNMPEV 2515
Query: 2672 DKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHV 2731
DKYGT + IRQ ++H +Y T + Q+V NP + G + R RH
Sbjct: 2516 DKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS--GSFTIDSRLQRHF 2573
Query: 2732 PVVYVDYPGPASLTQIYGTF---NRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDT 2788
V V +PG +LT IY T + A + +++ + L AA + + F
Sbjct: 2574 CVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTA 2633
Query: 2789 -QPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTD 2847
+ HY+++ R+++ +G+ + + P++ L+R+W HE R++ D++V+++++
Sbjct: 2634 IKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLD-LVRLWLHETERVYGDKMVDEKDQETLH 2692
Query: 2848 ENIDTVALKHFPNIDREKAMSRPILYSNWLS----KDYIPV-DQEELRDYVKARLKVFYE 2902
K F ++ E ++P ++ ++ Y+PV D L + L + E
Sbjct: 2693 RVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNE 2752
Query: 2903 EELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIK 2962
+ LVLF + + H+ RI+RI P+G+ LL+GV G+GK +LSR A+++GL V+QI
Sbjct: 2753 VNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQIT 2812
Query: 2963 VHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFE 3022
+ + Y D DL ++ KN F+M +S V + FL +N LLA+GE+PGLF
Sbjct: 2813 LKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFM 2872
Query: 3023 GDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATS 3082
DE +++ + + G M D+ E +K+F +V R L V+ +P L+ RA
Sbjct: 2873 EDEVENIISSMRPQVKSLG-MNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKF 2931
Query: 3083 PALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREA 3142
PA+ N ++WF +W +AL V F LE+ I P + +
Sbjct: 2932 PAVVNCTAIDWFHEWPEDALVSVSARF-----LEETEGI--------------PWEVKAS 2972
Query: 3143 IVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLN 3202
I +VH T+++ + R TP+ +L+ I Y NL +KR+EL + L
Sbjct: 2973 ISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLE 3032
Query: 3203 VGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQE 3262
GL K++ T QV++L+ L I+ EL+ KN +A+ ++ + + ++ K+K ++ + +
Sbjct: 3033 NGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEV 3092
Query: 3263 QLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALE 3322
++ + + +KQ + + DL K EPA++ AQ A+ ++ K +L E++S +PP AV
Sbjct: 3093 KVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTA 3152
Query: 3323 SICLLL---GESTTD--WKQIRSIIMR-ENFIPTIVNFSAEEISDAIREKMKKNYMSNPS 3376
++ +L G+ D WK + ++ + + F+ ++ F E I +A + K Y NP+
Sbjct: 3153 AVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQGNPT 3211
Query: 3377 YNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQM 3436
++ E + S A + W I + + ++ V P R L++ + + Q+K + ++
Sbjct: 3212 FDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNK 3271
Query: 3437 IRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETF 3496
I +L A+++ + +E + + A + + L+ L++E RW ++ E F
Sbjct: 3272 IAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENF 3331
Query: 3497 KNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNL----FTTWSHHLQQANIQFRTDIARTEY 3552
++Q T+ GD LL +AF++Y GYF ++ R L + + H+L+ I +
Sbjct: 3332 RSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLK-VPIPITNGLDPLSL 3390
Query: 3553 LSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDR----K 3608
L++ + W LP+D + TENA +L R+PLI+D Q ++I N+Y+ +
Sbjct: 3391 LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIR 3450
Query: 3609 ITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQ 3667
+ + S+LD +E A+ G+ LL++++ E+ DPVL+P+L R + G I +GD+
Sbjct: 3451 LGQKSYLDV-----IEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGK--YIKIGDK 3503
Query: 3668 DIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEK 3727
+++ P F + L T+ + P++ ++ T +NF VTR L+ Q L V+ ERPD+++
Sbjct: 3504 EVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQL 3563
Query: 3728 RSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEET 3787
+++L K Q EF++ L++LE SLL L+ G L D ++ LE K A+E+ KV E
Sbjct: 3564 KANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEA 3623
Query: 3788 DIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLK 3847
I ++ + Y P + S +YF + L +I+ +YQ+SL+ F ++ +
Sbjct: 3624 KITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPAN 3683
Query: 3848 GVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKG-TVGEPTYDAEFQ 3906
V QR+ +T ++ + ARG+ +D + F LA++ + ++ + E
Sbjct: 3684 EV---KQRVINLTDEITYSVYMYTARGLFERDKLIF---LAQVTFQVLSMKKELNPVELD 3737
Query: 3907 HFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSS 3965
LR AG + L + + LS + FK+L + ++ +++ ++S +
Sbjct: 3738 FLLR---FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEA 3794
Query: 3966 PEQTV-PYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQP 4024
PE+ + P W +T A+ +L +++ RPDR+ FV +G F+
Sbjct: 3795 PEKEIFPKEWKNKT-------ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVE 3847
Query: 4025 LDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAE-----QNTQITSIAIGSAEGFNQ 4079
++ E P+T + PG D VE L + N ++ ++++G +
Sbjct: 3848 FSKSY---EESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEV-V 3903
Query: 4080 ADKAINTAVKSGRWVML--------KNVHLAPGWLMQLEKKL--HSLQPHACFRLFLTME 4129
A+ A++ A + G WV+L +N+HL WL L+KKL +S H +R+F++ E
Sbjct: 3904 AENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAE 3963
Query: 4130 INPK-----VPVNLLRAGRIFVFEPPPGVKANMLRTFS--SIPVSRICKSPNERARLYFL 4182
P +P +L EPP G+ AN+ + + +C E + F
Sbjct: 3964 PAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFA 4023
Query: 4183 LAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSA 4242
L +FHA++ ER ++ GW++ Y F DL + + + +L+ + K+PW
Sbjct: 4024 LCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE---------ANPKVPWDD 4074
Query: 4243 LKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRR 4302
L+ L + +YGG + +++D+RL T+L T + + LA Q+P +
Sbjct: 4075 LRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLA------PGFQIPPNLDY 4128
Query: 4303 EEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDED--------- 4353
+ + ++++ ++P GL NAE LT + +L+MQ E +
Sbjct: 4129 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 4188
Query: 4354 ----DLAYAETEKKTR-TDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENI-KD 4407
L +E+K + G P + + L IP+T + + + K
Sbjct: 4189 EKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKT 4248
Query: 4408 PLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHY 4467
P +E + L ++R+ L ++ +G+ T + L L +P +W
Sbjct: 4249 PYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVAR 4308
Query: 4468 TVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQY 4527
P+ M + W +D RI++L+ + A V L G F P++++TA Q
Sbjct: 4309 AYPSMMGLAAWYADLLLRIRELEAWTTDFALPTT-------VWLAGFFNPQSFLTAIMQS 4361
Query: 4528 VAQANSWSLEELCLEVNVTTSQGATLDAC---SFGVTGLKLQGATCNNNKLSLSNA---- 4580
+A+ N W L+++CL V VT + A V GL ++GA + ++ A
Sbjct: 4362 MARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKE 4421
Query: 4581 ISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGV 4640
++ A+P+ ++ + E K ++ PVY R + F + TKE + V
Sbjct: 4422 LTPAMPVIFIKAIPVDRMETK-NIYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAV 4479
Query: 4641 AVL 4643
A+L
Sbjct: 4480 ALL 4482
Score = 47.4 bits (111), Expect = 3e-04
Identities = 116/640 (18%), Positives = 252/640 (39%), Gaps = 73/640 (11%)
Query: 238 DPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQ-----EISFWLNLERALYRIQEKR 292
D L+ +++ + W +I+ V D A L E FW L I E+
Sbjct: 186 DNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQL 245
Query: 293 ESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATE--- 349
P+V ++IL+ K + + T + + L+ ND +K PL LL E
Sbjct: 246 NRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLK--PLRILLEEMEQAD 303
Query: 350 LDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKV----LGTRKLMHVA 405
+ + + + I T R++ I ++ +Q++++ L +++
Sbjct: 304 FTMLPTFIAKVLDTICFIWATSEYYNTPARII-VILQEFCNQIIEMTRTFLSPEEVLKGL 362
Query: 406 YEEFEKVMVACF-------EVFQTWDDEYEKLQVLLRDIVKRKREENLKMVW-RINPAHR 457
E E+V+ E++QT+D +++ +D E + + RIN +
Sbjct: 363 QGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQ 422
Query: 458 KLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADA 517
++Q ++++ K + +L + + +R + G + +V E++ AD
Sbjct: 423 RIQT-IEELYKTAIEFLKLEKIELGGVRGNLL-------GSLVTRIYDEVFELVKVFADC 474
Query: 518 NAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKN 577
+ D LD + A + + +DR I + D K+
Sbjct: 475 --------------KYDPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKS 520
Query: 578 ANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSH 637
+ ++ + L RP I + + +++ ++++ + Q S+ +
Sbjct: 521 SAKLLYMCG---GLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPL 577
Query: 638 V-RDLPPVSGSIIWAKQIDRQLTA---YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKL 693
+ +++PPV+G + W+ ++ +L ++K VE + G E + QK + + R
Sbjct: 578 IHKNMPPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLR--C 635
Query: 694 NTQEIFDDWARKVQQR---NLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEV 750
+ ++I+ W V Q NLG + +R N+ + VNF ++ + +EV
Sbjct: 636 HREKIYQQWVAGVDQDCHFNLG--------QPLILRDAASNL--IHVNFSKALVAVLREV 685
Query: 751 RNLKWLGFRVPLAIVNKAH---QANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAG 807
K+L F+ I + A N+ + + +E + + + + + L+ +
Sbjct: 686 ---KYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIVGWYNEIKTIVKAVEFLLIKSE 742
Query: 808 LKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKV 847
L+ L++ L W + Y+Q + E + N Q ++
Sbjct: 743 LEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNRM 782
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 1308 bits (3385), Expect = 0.0
Identities = 938/3431 (27%), Positives = 1627/3431 (47%), Gaps = 329/3431 (9%)
Query: 1348 EQPWVSVQPRKLRQNLD----ALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIEL 1403
E P+ V P ++ ++ L K+F A + V+ ++ + + L+ +
Sbjct: 785 EGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVI 844
Query: 1404 KSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEF 1462
+ L+ RHW+ + + S+ T+ D++L+ + + A E +LE+
Sbjct: 845 CNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKA 904
Query: 1463 LKQIREVWNTYELDLVNYQNKCRLI-RGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDAL 1521
++++ W+ E + +Y+ I D++ + +HI M+ SP+ K +E+
Sbjct: 905 MEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMR 964
Query: 1522 SWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKK 1581
WE KL + + D W+ VQ W+YLE IF+ S DI +P E +RF ++ + +M+
Sbjct: 965 EWEGKLLLLQEILDEWLKVQATWLYLEPIFS-SPDIMSQMPEEGRRFTAVDKTWRDIMRS 1023
Query: 1582 VSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEII 1641
V + V+ V+ I + L++ +LL I K L EYLE++R FPRF+F+ +++LLEI+
Sbjct: 1024 VMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEIL 1083
Query: 1642 GNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITE-HPKINE 1700
+K+ ++Q H KK F G++ + E + + S EGE V +S + ++ +
Sbjct: 1084 SETKDPTRVQPHLKKCFEGIAKVEFTETLDIT-HMKSSEGEVVELIEIISTAKARGQVEK 1142
Query: 1701 WLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSE 1760
WL +E+ M ++ K+ ++ + + I W+ + Q V+ +QI W++
Sbjct: 1143 WLVELERVMINSIHKVTGDATFAYTKYER---------INWVRDWPGQTVLCVSQIFWTK 1193
Query: 1761 NVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRD 1820
V+TA+ MG L + ++ + ++ + M+ R L L+ VH RD
Sbjct: 1194 EVQTAIP-MGIKALEQYLKTCNRQIDDIVTLVRGKLSMQN----RVTLGALVVLDVHARD 1248
Query: 1821 VTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLV 1880
V SL+K I + FEWLSQ+R+Y+ L +M NA YG+EYLG +LV
Sbjct: 1249 VLSSLVKKNISDDSDFEWLSQLRYYWQENH------LETKMINAGLRYGYEYLGNSPRLV 1302
Query: 1881 QTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQA 1940
TPLTDRCY T+ AL LGG+P GPAGTGKTE+ K L + + +VFNC + D+ A
Sbjct: 1303 ITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLA 1362
Query: 1941 MGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCE 2000
+G+ F GL GAW CFDEFNR++ +LS V+QQ+ IQ + ++
Sbjct: 1363 LGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGAD----------ILM 1412
Query: 2001 LLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFR 2060
++K+ P A+FITMNPGYAGRS LPDNLK LFR++AM PD +IA+++LYS GF
Sbjct: 1413 FEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFV 1472
Query: 2061 TAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGE 2120
TA L+ KIV ++LC EQLSSQ HYD+G+RA+KSVL +AGN+K K E EE
Sbjct: 1473 TARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL----KYPNENEEI-- 1526
Query: 2121 AVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALRE 2180
+L++S+ + +PK ++ D+PL + SD+FPGV+ + + L
Sbjct: 1527 ---------------LLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLA 1571
Query: 2181 ELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKA 2240
+K C M L ++ + EK+LQ+Y++ + HG M+VG GK+ A+RVL A
Sbjct: 1572 AIKDNCASMNL------QMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGA 1625
Query: 2241 LERL------EGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGE 2294
L + E + +++PK+++ LYG D + EW+DG+ R SV +
Sbjct: 1626 LNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPD 1685
Query: 2295 LQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLA 2354
R+W++FDG VD W+EN+N+VLDDNK L L +GE + + P + ++FE DL+ A+ A
Sbjct: 1686 ---RKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPA 1742
Query: 2355 TVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQ 2414
TVSRCGM++ +L + +++ L A+ ++Q
Sbjct: 1743 TVSRCGMIYMEPHMLGWRPLMLSWVNLL------------------------PASVSVIQ 1778
Query: 2415 IQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNA 2474
+ + S + K H +L D +R L +L
Sbjct: 1779 KEFIMGLFDRMVPVSVEFIRK---HTKELSPTSDTNLVRSLMNLIDCFMD---------- 1825
Query: 2475 NHPDFPMQIEQLER-------YIQRYLVYAILWSLSG----DSRLKMRAELGEYIR---- 2519
DF +++ ER ++ +++++WS+ D RLK L E +
Sbjct: 1826 ---DFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPIS 1882
Query: 2520 ------------------RITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHK 2561
+ TVP P I + G+W PW K+ +
Sbjct: 1883 DRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKD 1942
Query: 2562 VAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVG-- 2619
V +++VPTLDT+R+ AL+ KP + GP G+GK++ + + L + E+
Sbjct: 1943 VMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPL 2002
Query: 2620 -LNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQR 2678
+NFS+ TT + RR GV P LGK +V+F D++N+P + YG Q
Sbjct: 2003 LINFSAQTTAAQTQNIVMSKLDKRR--KGVFGPP--LGKRMVVFVDDVNMPAREVYGAQP 2058
Query: 2679 VISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDY 2738
I +RQ ++H +Y D + +KL IQ + A PP GR P++ R++RH ++ ++
Sbjct: 2059 PIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGG-GRNPVTPRYMRHFNIITINE 2117
Query: 2739 PGPASLTQIYG---TFNRAMLRLIPS--LRTYAEPLTAAMVEFYTMSQERFTQDTQPHYI 2793
S+ I+ T++ + P L + + M + + + HY+
Sbjct: 2118 FSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYL 2177
Query: 2794 YSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTV 2853
++ R+ +R ++G+ + RP T E + R+W HE LR++ DRL+++ +R W I +
Sbjct: 2178 FNLRDFSRVIQGVCLS-RPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEI 2236
Query: 2854 ALKH--------FPNIDR------EKAMSRPILYSNWLSKDYIPVDQEELRDYVKARL-- 2897
+ F +D E R +++ ++ + E+ D R+
Sbjct: 2237 LRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIADVDNLRMIV 2296
Query: 2898 KVFYEEELDVP-----LVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAW 2952
++ EE ++ LVLF ++H+ RI RI +QP+ H LL+GV G+G+ +++R A
Sbjct: 2297 EIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAH 2356
Query: 2953 MNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLL 3012
M SV+Q+++ + Y ++ EDL+ +LR+ + F+ ++ + + FLE ++ LL
Sbjct: 2357 MADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLL 2416
Query: 3013 ANGEVPGLFEGDEYATL---MTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMN 3069
GE+P LF DE + M Q K S L+ F LHVV M+
Sbjct: 2417 NAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMS 2476
Query: 3070 PSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVV 3129
P + ++R PAL N C ++WF W +AL V F ++++
Sbjct: 2477 PIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMS------------- 2523
Query: 3130 YDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRG----GRTMAITPRHYLDFINHYAN 3185
E I + C+ + ++ H + L+K R +TP YL+ I+ +
Sbjct: 2524 -----------EEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKL 2572
Query: 3186 LFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVK 3245
L +KRSE+ + + VGL K+ QV ++ +L +L+V + ++ + + K
Sbjct: 2573 LLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEK 2632
Query: 3246 DQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKE--------DLDKVEPAVIEAQNAVK 3297
+ E K E++ K E IA++Q + DL P + A A+
Sbjct: 2633 ESVEVAKT--------EKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALD 2684
Query: 3298 SIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTD--------------WKQIRSIIM 3343
++ Q + V+SM +PPA VKL +E+IC+L G W + ++
Sbjct: 2685 TLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLG 2744
Query: 3344 RENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYA 3403
F+ ++ + + I A ++KNY+ NP + E + AS A + KW IA +Y
Sbjct: 2745 DMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYD 2804
Query: 3404 DMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKA 3463
+ K V P + +L E + K + + +++++ +AR ++ + + ++
Sbjct: 2805 KVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLEN 2864
Query: 3464 DLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQ 3523
+ K+ R+ L+ L E+ RW T+ + GD L+S+ +AY G F
Sbjct: 2865 QVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTST 2924
Query: 3524 MRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRF 3583
RQN W+ + +I D + L A W + LP+D +N I++
Sbjct: 2925 YRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984
Query: 3584 NRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYD 3642
R+PL+IDP QA ++I N K + + + + LE+ ++FG P+L+++V E D
Sbjct: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044
Query: 3643 PVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFT 3702
P+L P+L ++ + GG I LGD I+ +P F +++T+ + P+ +VT +NF
Sbjct: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104
Query: 3703 VTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILD 3762
+T +Q Q L V+ ERPD++E++ L+ E + +L+++E +L+ L+ +G IL+
Sbjct: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164
Query: 3763 DDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIH 3822
D+T I L + K A E+++K E + ++++T Y P++ S ++F++ L I
Sbjct: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224
Query: 3823 FLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHIT 3882
+YQYSL +F++++ + EN + +RL I+ + V R + +D +
Sbjct: 3225 PMYQYSLTWFINLF-ILSIENSEKSEIL--AKRLQILKDHFTYSLYVNVCRSLFEKDKLL 3281
Query: 3883 FAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLP 3942
F+ L + + E + FL I L L + + + RL LP
Sbjct: 3282 FSFCLT---INLLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLP 3338
Query: 3943 AFKDLIAK-VQADEQFGIWLDSSSPEQTV-PYLWSEETPATPIGQAIHRLLLIQAFRPDR 4000
AFK + + ++ + + DS P V P W ++ R+L+I+ RPD+
Sbjct: 3339 AFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDK------ANEFQRMLIIRCLRPDK 3392
Query: 4001 LLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAA 4060
++ M F+ LG +F I P DL G + P++ PG D + A
Sbjct: 3393 VIPMLQEFIINRLGRAF--IEPPPFDLAKAFG-DSNCCAPLIFVLSPGADPMAALLKFAD 3449
Query: 4061 EQ---NTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQ 4117
+Q ++++S+++G +G A K + AVK G WV+L+N HLA W+ LEK L
Sbjct: 3450 DQGYGGSKLSSLSLGQGQG-PIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELS 3508
Query: 4118 P---HACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVS-----RI 4169
P H FR++LT +P PV++L+ G E P G++AN++R++ P+S
Sbjct: 3509 PESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGS 3568
Query: 4170 CKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKG 4229
CK P E +L + L +FHA++QER ++ PLGW+ YEF E+DLR + + +L+
Sbjct: 3569 CKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQY--- 3625
Query: 4230 RQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVD 4289
+++P+ AL+ + + YGGRV +++D+R L + L + F ++ K D
Sbjct: 3626 ------EELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENS---DYKFD 3676
Query: 4290 GHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQML 4349
+P + ++++ + LP T P G+ NA D+ + Q+L
Sbjct: 3677 SSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANA----------DITKDQSETQLL 3726
Query: 4350 EDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTL---SHLKRTVENIK 4406
D L T++ S G + ++ AS+ L +P + ++R
Sbjct: 3727 FDNILL--------TQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYT 3778
Query: 4407 DPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSH 4466
+ +E+ KLL+ +R ++ + +G + L +++ ++ +P W
Sbjct: 3779 QSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMG 3838
Query: 4467 YTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQ 4526
+ P+ + +V+DF R+K LQ L G F +A++T +Q
Sbjct: 3839 KSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPP--------VFWLSGFFFTQAFLTGAQQ 3890
Query: 4527 YVAQANSWSLEELCLEVNV-TTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNA----I 4581
A+ + ++ L + V + + GL L GA+ N L+ + +
Sbjct: 3891 NYARKYTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKIL 3950
Query: 4582 STALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLI--------FTVDFEIATKEDPR 4633
+P+ L+ K+ + K+ S V P+Y R ++ F + + + +
Sbjct: 3951 YDTVPVMWLKPCKRADIPKRPSYVA-PLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKE 4009
Query: 4634 SFYERGVAVLC 4644
+ RGVA+LC
Sbjct: 4010 HWIGRGVALLC 4020
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 1299 bits (3361), Expect = 0.0
Identities = 961/3522 (27%), Positives = 1700/3522 (48%), Gaps = 300/3522 (8%)
Query: 1223 DIMRRKDSAIQQQVANLQMKIVQED--------RAVESRTTDLLT---DWEKTKPVTGNL 1271
D +R + +Q + ++Q +VQ +VE D++ +E P+ N+
Sbjct: 1166 DTLRYSFNKLQSKAVSVQEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPMVPNI 1225
Query: 1272 RPEEALQALTIYEGKFGRLKDDREKCAKAKE--ALELTDTGLLSGSEERVQVALEELQDL 1329
P+EA L I++ F L + ++ L +TD +L + + + + LQ L
Sbjct: 1226 PPQEASNRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNL----LQKL 1281
Query: 1330 KGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRL 1389
G++ V I E W V K+ L N+ + P L+ + ++ +++
Sbjct: 1282 YGLYDT---VMSSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKR 1338
Query: 1390 LKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE--LTLGQIWDVDLQKNEAIVK 1447
+ + + L+ + ++A+K RHW ++ + + V L I + L K++ ++
Sbjct: 1339 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIE 1398
Query: 1448 DVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLI-RGWD--DLFNKVKEHINSV 1504
D+ + A E +E L Q+ E W L ++ K L+ +G + ++ +++ + +
Sbjct: 1399 DICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVL 1458
Query: 1505 SAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVE 1564
++ + Y F+++ +W KL+ + + W+ VQ WVYLE +F G DI LP E
Sbjct: 1459 GSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGG-DIAKQLPQE 1517
Query: 1565 TQRFQSISTEFLALMKKVSKSPLVMDV-LNIQGVQRSLERLADLLGKIQKALGEYLERER 1623
+RFQ+I ++ +M++ ++P V++ + + + + L L + L QK+L YLE++R
Sbjct: 1518 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1577
Query: 1624 SSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILN-EDNSVVLGISSREGE 1682
FPRF+FV D LLEI+G + + +Q H + ++ + + +D ++ + SREGE
Sbjct: 1578 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1637
Query: 1683 EVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWI 1742
+++ S+ + WL + K +L ++ + ++ G + ++
Sbjct: 1638 KIVLDN--SVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQL-------LPFL 1688
Query: 1743 DKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPP 1802
+ AQ+ +L Q+ W+ + E AL + D + LN L +
Sbjct: 1689 SHFPAQVGLLGIQMLWTHDSEEALRN--AKDDRKIMQVTNQKFLDILNTLISQTTHDLSK 1746
Query: 1803 LRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMA 1862
R K E LIT VHQRD+ L+K I + FEWL Q RFYF + L Q + +
Sbjct: 1747 FDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFK----EDLDQTVVSIT 1802
Query: 1863 NAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQ 1922
+ F Y E+LG D+LV TPLTDRCY+T+ QAL +GG+P GPAGTGKTE+ K +G
Sbjct: 1803 DVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRC 1862
Query: 1923 LGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEAL 1982
LG++V+VFNC + DF+ +GRIF GL Q G+WGCFDEFNR+E +LS +QQ+ + A
Sbjct: 1863 LGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTAR 1922
Query: 1983 REHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT 2042
+E C V ++P+ IF+TMNPGYAGR LP+NLK FR++AM
Sbjct: 1923 KERKKQFIFSDG---DC------VDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMM 1973
Query: 2043 KPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGN 2102
PDRQ+I +V L S GF +LA K +KLC+EQL+ Q HYDFGLR + SVL + G+
Sbjct: 1974 VPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGS 2033
Query: 2103 VKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLS 2162
KR R + E I+++ + + + KLV ED PL SL++
Sbjct: 2034 QKRARPED---------------------SELSIVMRGLRDMNLSKLVDEDEPLFLSLIN 2072
Query: 2163 DVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMM 2222
D+FPG+Q L+ + Q +G W K++QLY+ + + HGLM
Sbjct: 2073 DLFPGLQLDSNTYAELQNAVAHQVQI------EGLINHPPWNLKLVQLYETSLVRHGLMT 2126
Query: 2223 VGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTH 2282
+GPSGSGK+ +L+KA G ++PKAI+ ++G LD T +WTDG+F+
Sbjct: 2127 LGPSGSGKTTVITILMKAQTEC-GRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFST 2185
Query: 2283 VLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIM 2342
+ RK + + +GE +++ DG VD W+ENLNSVLDDNK LTL NG+R+ + P+ +++
Sbjct: 2186 LWRKTLKAKKGE---NIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLL 2242
Query: 2343 FEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKE 2402
FEV +++ A+ ATVSR GMV+ S LS I +L K+
Sbjct: 2243 FEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL---------------------KK 2281
Query: 2403 DEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSML 2462
+EAA + T+ + F K L M L + ++L
Sbjct: 2282 RTAQEAAVFL--------TLYEKVFEDTYTYMK-----LNLNPKMQLLECNYIVQSLNLL 2328
Query: 2463 HQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRIT 2522
+ + + +E L + L++++ L +SR K+ A L ++ ++
Sbjct: 2329 EGLIPSKEEGGVS------CVEHLHKLFVFGLMWSLGALLELESREKLEAFLRQHESKLD 2382
Query: 2523 TVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAA-PDVVVPTLDTVRHEALL 2581
+P N + ++ V+ G+W W K+ T + ++VP +D +R L+
Sbjct: 2383 LPEIPKGSNQTMYEFYVTDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLI 2442
Query: 2582 YTWLAEHKPLVLCGPPGSGKTMTLFSALRAL-PDMEV-VGLNFSSATTPELLLKTFDHYC 2639
T +HK ++L G G+ KT+ + + L+ P++++ LNFSSAT P + +T + Y
Sbjct: 2443 DTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIESYV 2502
Query: 2640 EYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQ- 2698
+ R G P G+ + +F D+IN+P ++++G Q +RQM+E G Y
Sbjct: 2503 DKR---IGSTYGPPG-GRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPG 2558
Query: 2699 TWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYG--------- 2749
+ + +Q + A P GR + R R V P AS+ +I+G
Sbjct: 2559 DFTTIVDVQLIAAMIHP-GGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDP 2617
Query: 2750 --TFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIF 2807
+F + +I +L ++ V + + ++ HYI++ R+++R +G+
Sbjct: 2618 CRSFKPQICEMIVNL------VSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2671
Query: 2808 EALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRW--------TDENIDTVA----- 2854
++ E + L+ ++ HE R+ DR + E+ +W +ENI + A
Sbjct: 2672 -TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCIL 2730
Query: 2855 --------LKHFP----NIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYE 2902
L+ P + + P +Y S D++ E+L+ Y + ++
Sbjct: 2731 PEPYFVDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDFL---AEKLQFYQRQFNEIIRG 2787
Query: 2903 EELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIK 2962
LD LV F + + H+++I RI R G+ LL+GV G+GK +LSR +++ G ++QI
Sbjct: 2788 TSLD--LVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQIT 2845
Query: 2963 VHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFE 3022
+ R Y + +DL+ + + +G + I FI +S + D FLE +N LL++GE+ LF
Sbjct: 2846 LTRSYNVTNLTDDLKALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFA 2905
Query: 3023 GDEYATLMTQCKEGAQKEGLML--DSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAA 3080
DE + TQ K L + + LY++F S+ +NLHVV +P E + R+
Sbjct: 2906 RDEMDEI-TQGLISVMKRELPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSL 2964
Query: 3081 TSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHR 3140
P L + C ++WF W EAL V +Y + DY V ++ +
Sbjct: 2965 KFPGLISGCTMDWFSRWPREALIAVA------------SYFLSDYNIVCSSEI------K 3006
Query: 3141 EAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMH 3200
+V + H + ++ +R R +TP+ YL FIN Y N++ EK + EQ
Sbjct: 3007 RQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAER 3066
Query: 3201 LNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEI 3260
+N+GL K+ E + V +L +DL +K +EL V + A++ L ++ Q + K K QE+
Sbjct: 3067 MNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEV 3126
Query: 3261 QEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLA 3320
+++ K + I +++ + L+ +PA+ EA+ A+ +IK + VR +A PP +
Sbjct: 3127 KDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRI 3186
Query: 3321 LESICLLLGES----TTD---------WKQIRSIIMRENFIPTIVNFSAEEISDAIREKM 3367
++ + LL + T D W + ++ F+ ++ F + I++ E +
Sbjct: 3187 MDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELL 3246
Query: 3368 KKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQ 3427
+ Y + Y +E + ++ W +A + + + V PL+ L K E
Sbjct: 3247 QP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVAN 3305
Query: 3428 QKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERE 3487
+ + + ++ + +A + + + ++ ++E + D K+ ++ L+ LS E+
Sbjct: 3306 AELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKI 3365
Query: 3488 RWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLF-TTWSHHLQQANIQFRTD 3546
RW + S+ FK Q++ + GD LL F++Y G F+Q R L W L+ I F +
Sbjct: 3366 RWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTEN 3425
Query: 3547 IARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKD 3606
+ L + W LP DDL +N I++ + RYPL+IDP Q +I ++ K+
Sbjct: 3426 LNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKE 3485
Query: 3607 RKITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLG 3665
+ TS FR +LE +L G PLL++D+ E DP L+ VL + ++G + +G
Sbjct: 3486 NDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTTFKVKVG 3545
Query: 3666 DQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVD 3725
D++ D+ +F ++++T+ P F P++ ++ + ++FTVT L++Q L V+ E+ +++
Sbjct: 3546 DKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELE 3605
Query: 3726 EKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVE 3785
+R LL+ + ++++LE +LL L+ KG ++DD+++I L K+ AAEV+ K+
Sbjct: 3606 AERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLH 3665
Query: 3786 ETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPN 3845
++ +++ P +T S +YF + + ++ +YQ SL FL ++ + +
Sbjct: 3666 VAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARS-- 3723
Query: 3846 LKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKL---KGTVGEPTYD 3902
+ +R++ I + L F RG L+++H +LL +K+ +GTV
Sbjct: 3724 -EKSPLPQKRITNIIEYLTYEVFTYSVRG-LYENHKFLFVLLMTLKIDLQRGTVKH---- 3777
Query: 3903 AEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEA-VVRLSCLPAFKDLIAKVQADEQ-FGIW 3960
EFQ ++G + P+ ++ +V LS LP F +++ ++ +E+ + W
Sbjct: 3778 REFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSW 3837
Query: 3961 LDSSSP-EQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMS 4019
D +P E+ +P +++ H+LLLI+++ PDR + A +++ +L E +
Sbjct: 3838 FDKDAPEEEIIPDGYNDSL------DTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 3891
Query: 4020 IMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQ 4079
+ L+ T E TP++ G D + ++ LA + + +I++G + +
Sbjct: 3892 PVILNLEKT---WEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECRTISMGQGQEVH- 3947
Query: 4080 ADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQ-PHACFRLFLTMEINPKVPVNL 4138
A K I +++ G WV+L+N HL ++ +L + L + + FR+++T E + + P+ L
Sbjct: 3948 ARKLIQMSMQQGGWVLLQNCHLGLEFMEELLETLITTEASDDSFRVWITTEPHDRFPITL 4007
Query: 4139 LRAGRIFVFEPPPGVKANMLRTFSSI--PVSRICKSPNERARLYFLLAWFHAIIQERLRY 4196
L+ F EPP GV+A + RTF+ I + I P + LY +A+ H+ +QER ++
Sbjct: 4008 LQTSLKFTNEPPQGVRAGLKRTFAGINQDLLDISNLPMWKPMLY-TVAFLHSTVQERRKF 4066
Query: 4197 APLGWSKKYEFGESDLRSACDTVDTWLD--DTAKGRQNISPDKIPWSALKTLMAQSIYGG 4254
PLGW+ YEF +D ++ + LD D KG + W+ ++ ++ + YGG
Sbjct: 4067 GPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKG--------VSWNTVRYMIGEVQYGG 4118
Query: 4255 RVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPD 4314
RV ++FD+RLLN F F+ + F+ F C G+K +P +++ ++++ LP
Sbjct: 4119 RVTDDFDKRLLNCFARVWFSEKMFEPSF---CFYTGYK---IPLCKTLDQYFEYIQSLPS 4172
Query: 4315 TQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEK----KTRTDSTS 4370
P GL NA+ + ++ + +Q E + ET + + D S
Sbjct: 4173 LDNPEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGV--GETREAIVYRLSEDMLS 4230
Query: 4371 DGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQD 4430
P ++ H S + + HL NI F +E+ +++ +R
Sbjct: 4231 KLPPDYIP--HEVKSRLI-----KMGHLNSM--NI------FLRQEIDRMQRVISILRSS 4275
Query: 4431 LADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQ 4490
L+D+ EG + LR ++ + +P+ W + + T+ W ++ ER Q
Sbjct: 4276 LSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVSWDSS-TLGFWFTELLERNAQF- 4333
Query: 4491 NISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQAN-SWSLEELCLEVNV---T 4546
S E + + G F P+ ++TA RQ V +A+ W+L+ + + V T
Sbjct: 4334 -------STWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEVLRQT 4386
Query: 4547 TSQGATLDACSFGVTGLKLQGATCN--NNKL--SLSNAISTALPLTQLRWVKQTNTEKKA 4602
+ + + GL + GA + N KL S + T LP+ + + T K
Sbjct: 4387 KEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINST-APKDP 4445
Query: 4603 SVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLC 4644
+ P+Y R DL F + T P + RGVA+LC
Sbjct: 4446 KLYVCPIYKKPRRTDLTFITVVYLRTVLSPDHWILRGVALLC 4487
Score = 58.5 bits (140), Expect = 1e-07
Identities = 71/347 (20%), Positives = 154/347 (44%), Gaps = 32/347 (9%)
Query: 513 DAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQL 572
+ D AI+ N+ Y+ VK+ D+ ++ + +I+ +E +I A +
Sbjct: 391 EGIDIMAIKFRNI-YQGVKKKQ-YDILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSF 448
Query: 573 GTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQA 632
G ++ + ++ RF L + P + I +++Q ++++ + SQ
Sbjct: 449 GKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAELDATKKLY-----HSQK 502
Query: 633 CKMSHVRDLPPVSGSIIWAKQIDRQLTA---YMKRVEDVLGKGWENHVEGQKLKQDGDSF 689
R++PP++G I+W +Q+ R+++ Y + D+L + +G+ + + +
Sbjct: 503 DDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDIL-----SSPDGKAVIRQYNKI 557
Query: 690 RMKLNTQEI--FDDWARKVQQRNLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLS 747
L E+ W R++ Q + + +F R KL VNF P+I+ +
Sbjct: 558 SYVLVEFEVVYHTAWIREISQLHYALQATLFV--------RHPETGKLLVNFDPKILEVV 609
Query: 748 KEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAG 807
+E + + + VP ++L + L ++ Y+ C++V ++L+
Sbjct: 610 RETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS-VFVNLMTPK 668
Query: 808 LKKEVQALIAEGI-ALVWESYKLDPYVQ--RLAETVFN-FQEKVDDL 850
+KK V++++ +G+ L W S L+ + Q L +FN +K+ DL
Sbjct: 669 MKK-VESVLRQGLTVLTWSSLTLESFFQEVELVLDMFNQLLKKISDL 714
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 1256 bits (3249), Expect = 0.0
Identities = 922/3412 (27%), Positives = 1633/3412 (47%), Gaps = 345/3412 (10%)
Query: 1366 LLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWV 1425
L+ L PA R + + K Y+ I + + +KDRHW+Q+ + +
Sbjct: 913 LIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISC---NPGMKDRHWQQISEIVGYEIK 969
Query: 1426 VSELT-LGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNK- 1483
+E T L + + K ++ + A E +LE+ L +++ W V Y++
Sbjct: 970 PTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVKYRDTD 1029
Query: 1484 CRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRR 1543
++ DD+ + +H+ M SP+ K E + WE+KL RI D W+ Q
Sbjct: 1030 TNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLKCQAT 1089
Query: 1544 WVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLER 1603
W+YLE IF+ S DI +P E ++F + + + +LM + K ++ + + L+
Sbjct: 1090 WLYLEPIFS-SEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPRMAEKLQE 1148
Query: 1604 LADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSS 1663
LL IQK L +YLE++R FPRF+F+ +++LLEI+ +K+ ++Q H KK F G++
Sbjct: 1149 ANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKKCFEGIAK 1208
Query: 1664 IILNEDNSVVLGISSREGEEVMFKTPV-SITEHPKINEWLTLVEKEMRVTLAKLLAESVT 1722
+ DN ++G+ S E E V F + + +WL VE+ M ++ +++ +
Sbjct: 1209 LEFT-DNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGI- 1266
Query: 1723 EVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVL 1782
E + K P + W+ ++ Q+V+ + I W++ V AL+ +++L
Sbjct: 1267 --EAYVKV----PRNH--WVLQWPGQVVICVSSIFWTQEVSQALAE----------NTLL 1308
Query: 1783 SNVEVTLNVLADSVLMEQPPLR---RRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWL 1839
++ + + +A V + + L R L L VH RDV L + ++ + F+W+
Sbjct: 1309 DFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWI 1368
Query: 1840 SQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEAR 1899
SQ+R+Y+ V + + +Q+ + YG+EYLG +LV TPLTDRCY T+ AL+
Sbjct: 1369 SQLRYYW------VAKDVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLN 1422
Query: 1900 LGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDE 1959
LGG+P GPAGTGKTE+ K L L + +VFNC + D++AMG+ F GL Q GAW CFDE
Sbjct: 1423 LGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDE 1482
Query: 1960 FNRLEERMLSAVSQQVQCIQEAL-REHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITM 2018
FNR+E +LS V+QQ+ IQ+A+ R+ ++ T ++ ++P A+FITM
Sbjct: 1483 FNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGT-----------ELSLNPTCAVFITM 1531
Query: 2019 NPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDE 2078
NPGYAGR+ LPDNLK LFR++AM PD LI ++ LYS GF + LA KIV ++LC E
Sbjct: 1532 NPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSE 1591
Query: 2079 QLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILI 2138
QLSSQ HYD+G+RA+KSVL +AGN+K +K +E E +L+
Sbjct: 1592 QLSSQHHYDYGMRAVKSVLTAAGNLK------LKYPEEN---------------ESVLLL 1630
Query: 2139 QSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEE 2198
+++ + + K +A+D+PL ++SD+FPGV + + + L ++M L +
Sbjct: 1631 RALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKL------Q 1684
Query: 2199 VGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAH------ 2252
++ K++Q+Y++ + HG M+VG GK+ A++VL AL L +
Sbjct: 1685 PVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYK 1744
Query: 2253 IIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWV 2312
II+PKAI+ LYG D + EW DG+ + R+ S+ + R+WI+FDG VD W+
Sbjct: 1745 IINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDD---RKWIIFDGPVDAIWI 1801
Query: 2313 ENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTD 2372
EN+N+VLDDNK L L +GE + + + ++FE DL+ A+ ATVSRCGM++ L
Sbjct: 1802 ENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWK 1861
Query: 2373 MIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGL 2432
+ ++++ L S E +E + M ++QP L
Sbjct: 1862 PLKDSYMDTLPS---------------SLTKEHKELVNDMFM------WLVQPCLEFGRL 1900
Query: 2433 VTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQR 2492
K + + + RL +S L R V + + + +Q+ ++Q
Sbjct: 1901 HCKFVVQTSPIHLAFSMMRL------YSSLLDEIRAVEEEEMELGE-GLSSQQIFLWLQG 1953
Query: 2493 YLVYAILWSLSGDSRLKMRAELGEYIRRIT-----TVPLP-----TAPNI-----PIIDY 2537
+++++W+++G R + + R + P P T NI I D+
Sbjct: 1954 LFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDF 2013
Query: 2538 EV--SISGEWSPWQAKVPQIEVETHKVA-APDVVVPTLDTVRHEALLYTWLAEHKPLVLC 2594
SG W W + + E + A ++++PT++T R L T+L P++
Sbjct: 2014 YFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFV 2073
Query: 2595 GPPGSGKTMTLFSALRALPDMEVVG--LNFSSAT----TPELLLKTFDHYCEYRRTPNGV 2648
GP G+GK+ + L LP + +NFS+ T T ++++ D R G+
Sbjct: 2074 GPTGTGKSAITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLD------RRRKGL 2127
Query: 2649 VLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQF 2708
P+ GK V+F D++N+P + YG Q I +RQ ++HG ++ D T + + +
Sbjct: 2128 FGPPI--GKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLL 2185
Query: 2709 VGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGT---------FNRAMLRLI 2759
V A PP GR ++ RF RH+ ++ ++ LT+I+ + F+ LR
Sbjct: 2186 VTAMGPPGG-GRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHFGKGFDVMFLR-- 2242
Query: 2760 PSLRTYAEPLTAAMVEFYTMSQERFTQD-TQPHYIYSPREMTRWVRGIFEALRPLETLP- 2817
Y + L A Y + E F ++ HY+++ R+ +R ++G+ L P L
Sbjct: 2243 -----YGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVL--LCPHTHLQD 2295
Query: 2818 VEGLIRIWAHEALRLFQDRLVEDEERR------------WTDENIDTVALKHFPNIDREK 2865
VE IR+W HE R+F DRL++ E+R+ + I+ V + P
Sbjct: 2296 VEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVD 2355
Query: 2866 AMSRPILYSNWLSKDYIPVDQEELRDYVKARLKV-FYEEELD------VPLVLFNEVLDH 2918
R + + ++ + +E+ D + + + Y EE + + LV+F ++H
Sbjct: 2356 DNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEH 2415
Query: 2919 VLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRT 2978
+ RI R+ +Q +GHLLL+G+ G+G+ + ++ +MN +YQI++ + Y G D+ EDL+
Sbjct: 2416 ISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKK 2475
Query: 2979 VLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQ 3038
++ + G + F+ ++ + D F+E +N LL G+VP +F DE A ++ + + A+
Sbjct: 2476 IILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAAR 2535
Query: 3039 KEGLMLD-SHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDW 3097
+G ++ + +Y +F +VI + M+P + ++R P+L N C ++WF W
Sbjct: 2536 TQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSW 2595
Query: 3098 STEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQA 3157
T+AL V +F ++L+ + R +V+ C + +++ +
Sbjct: 2596 PTDALELVANKFLEDVELDD--------------------NIRVEVVSMCKYFQESVKKL 2635
Query: 3158 NARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEE 3217
+ + R +TP YL+ I + L + KR E+ + GL+K+ QV
Sbjct: 2636 SLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAV 2695
Query: 3218 LRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMS 3277
++R+L +L + + + K+ + +EA+ KK++ Q +++ + + +
Sbjct: 2696 MQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNE 2755
Query: 3278 VKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLG---ESTTD 3334
+ DL + PA+ A A+ ++ + V+SM NPP VKL +ESIC++ G E D
Sbjct: 2756 CEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPD 2815
Query: 3335 -----------WKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVN 3383
W + I+ F+ ++ + + I +++++ ++++P + ++
Sbjct: 2816 PSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIK 2875
Query: 3384 RASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEAS 3443
S AC + KW A Y + K V P R L++ E QK N+ ++ +
Sbjct: 2876 NVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDR 2935
Query: 3444 IARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTI 3503
+ +++ + ++ + ++ ++ K+ R+ L+ L E++RW + + + + +
Sbjct: 2936 LQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNL 2995
Query: 3504 AGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQ 3563
GD LLS+ +AY G F R W + I +D + + L + + WQ
Sbjct: 2996 TGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQ 3055
Query: 3564 ASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNL 3623
+ LP D +N I++ R+ L+IDP GQA ++I N K K+ F D + + L
Sbjct: 3056 IAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRML 3115
Query: 3624 ESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTR 3682
E+AL+ G P+L++++ E D + P+L + + G + LG+ I+ S F ++++TR
Sbjct: 3116 ENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTR 3175
Query: 3683 DPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRL 3742
+ P++ +V +NF +T LQ Q L V E+P+++EK++ L+ + + L
Sbjct: 3176 LRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHL 3235
Query: 3743 RQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYL 3802
+++E +L+ L+ KG IL+D+T I L + K + E++ K + + +++ Y
Sbjct: 3236 KEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYK 3295
Query: 3803 PLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIY-----HNVLYENPNL--KGVTDHTQR 3855
P++ ++I+F + L I +YQYSL +F+++Y H+ E NL K + DH
Sbjct: 3296 PVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHF-T 3354
Query: 3856 LSIITKDLFQVAFNRVARGMLHQDHITFAMLL--ARIKLKGTVGEPTYDAEFQHFLRGNE 3913
LSI +N V R + +D + F++LL +K K + E E +FL
Sbjct: 3355 LSI---------YNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITE-----EVWYFLLTGG 3400
Query: 3914 IVL-SAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIW---LDSSSP-EQ 3968
I L + P Q L+ + +VR S LP L+ + ++ G W DS+ P E+
Sbjct: 3401 IALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHL--EQNLGEWKLIYDSAWPHEE 3458
Query: 3969 TVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLT 4028
+P W Q + ++++++ RPD+++ F++ ++G+ ++ L +
Sbjct: 3459 QLPGSWK-------FSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGS 3511
Query: 4029 HIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAV 4088
+ + P VL S D T+ +I++G +G A K IN A+
Sbjct: 3512 YNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQG-PIAAKMINNAI 3570
Query: 4089 KSGRWVMLKNVHLAPGWLMQLEKKLHSL----QPHACFRLFLTMEINPKVPVNLLRAGRI 4144
K G WV+L+N HLA W+ LEK + +A FRL+LT + K PV++L+ G
Sbjct: 3571 KDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIK 3630
Query: 4145 FVFEPPPGVKANMLRTFSSIPVS-----RICKSPNERARLYFLLAWFHAIIQERLRYAPL 4199
EPP G++AN+LR++ + P+S + C ++ F L +FHA++QER + PL
Sbjct: 3631 MTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPL 3690
Query: 4200 GWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNE 4259
GW+ YEF ESDLR + + +L+D ++P+ AL L + YGGRV ++
Sbjct: 3691 GWNIPYEFNESDLRISMWQIQMFLNDY---------KEVPFDALTYLTGECNYGGRVTDD 3741
Query: 4260 FDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPS 4319
D+RLL + L + + + LA G P G + ++ ++ LP T P
Sbjct: 3742 KDRRLLLSLLSMFYCKEIEEDYYSLA---PGDTYYIPPHG-SYQSYIDYLRNLPITAHPE 3797
Query: 4320 WLGLPNNA-------------ERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRT 4366
GL NA E VLLT S +++E +LA K R
Sbjct: 3798 VFGLHENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVVE---ELAQDILSKLPRD 3854
Query: 4367 DSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQD 4426
+ + L P TV ++ L RF +L +
Sbjct: 3855 FDLEE---------------VMKLYPVVYEESMNTV--LRQELIRF--------NRLTKV 3889
Query: 4427 VRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERI 4486
VR+ L ++ + +G+ ++ L + N ++ G +P W+ + P+ + +V+D R+
Sbjct: 3890 VRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARL 3949
Query: 4487 KQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVT 4546
Q + + + G + ++++T Q A+ + ++ + E VT
Sbjct: 3950 TFFQE--------WIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVT 4001
Query: 4547 TSQGATLDACSFG--VTGLKLQGATCNNNKLSLSNAISTAL--PLTQLRWVKQTNTEK-- 4600
+ + G + GL L+GA + + + ++ L PL + W+K +
Sbjct: 4002 PQETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPL-PIIWLKPGESAMFL 4060
Query: 4601 KASVVTLPVY--------LNFTRADLIFTVDFEIATKEDPRSFYERGVAVLC 4644
+ PVY L+ T + + E+ T + + RGVA LC
Sbjct: 4061 HQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLC 4112
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 717 bits (1851), Expect = 0.0
Identities = 492/1640 (30%), Positives = 807/1640 (49%), Gaps = 180/1640 (10%)
Query: 1408 LKDRHWKQLMKRLHVNWVV-SELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQI 1466
++ RHWKQ+ + + + S TL ++ ++L + + A E +LE+ + +
Sbjct: 774 MRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTM 833
Query: 1467 REVWN--TYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWE 1524
W + + L C ++ D++ + + I M+ SP+ K FE + +WE
Sbjct: 834 IGTWEDIAFHISLYRDTGVC-ILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWE 892
Query: 1525 DKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSK 1584
D+L RI D W+ VQ +W+YLE IF S DI +P E ++FQ++ + +MK +K
Sbjct: 893 DRLIRIQETIDEWLKVQAQWLYLEPIFC-SEDIMQQMPEEGRQFQTVDRHWRDIMKFCAK 951
Query: 1585 SPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNS 1644
P V+ ++ G+ L+ +LL KI K L YLE++R FPRF+F+ ++++LEI+ +
Sbjct: 952 DPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSET 1011
Query: 1645 KNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITE-HPKINEWLT 1703
K+ ++Q H KK F G++ + N + + S EGE V +S + + +WL
Sbjct: 1012 KDPLRVQPHLKKCFEGIAKLEFLP-NLDIKAMYSSEGERVELIALISTSAARGAVEKWLI 1070
Query: 1704 LVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVE 1763
VE L+ SV +V I + + W+ ++ Q+V+ +Q+ W+ +
Sbjct: 1071 QVED--------LMLRSVHDV-IAAARLAYPESARRDWVREWPGQVVLCISQMFWTSETQ 1121
Query: 1764 TALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTR 1823
+S G L ++ LN + + V + R L L+T VH RDV
Sbjct: 1122 EVIS-----GGTEGLKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVM 1176
Query: 1824 SLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTP 1883
+IK + + F WL+Q+R+Y++ + V ++ N Y +EYLG +LV TP
Sbjct: 1177 DMIKMGVSHDTDFLWLAQLRYYWENENARV------RIINCNVKYAYEYLGNSPRLVITP 1230
Query: 1884 LTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGR 1943
LTDRCY T+ A LGG+P GPAGTGKTE+ K L L +VFNC + D+ AMG+
Sbjct: 1231 LTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGK 1290
Query: 1944 IFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLN 2003
F GL GAW CFDEFNR+E +LS V+QQ+ CIQ A+++ +
Sbjct: 1291 FFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKL----------VVFVFEG 1340
Query: 2004 KQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAE 2063
++K++P+ + ITMNPGYAGRS LPDNLK LFR++AM P+ LIA++ LYS GF A
Sbjct: 1341 TELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNAR 1400
Query: 2064 VLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVD 2123
L+ KIV ++LC EQLSSQ HYD+G+RA+K+VLV+AGN+ K+K E
Sbjct: 1401 PLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNL------KLKYPNEN------ 1448
Query: 2124 EGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELK 2183
E +L++S+ + PK ++ DIPL + SD+FPG++ + E
Sbjct: 1449 ---------EDILLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAH 1499
Query: 2184 KVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALER 2243
+ C L + ++EK++Q Y++ + HG M+VG + K+ VL L
Sbjct: 1500 EACNVHNL------QPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTL 1553
Query: 2244 L------EGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQK 2297
+ E + + ++PK+I+ L+G DP + EWTDG+ + R+ S E
Sbjct: 1554 MNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALS---ETPD 1610
Query: 2298 RQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVS 2357
R+W+VFDG +D W+E++N+VLDDNK L L +GE + + P + ++FE DL A+ ATVS
Sbjct: 1611 RKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVS 1670
Query: 2358 RCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEA--ASPMLQI 2415
RCGM++ L + + +++L L+ PL E E +A R G A P L
Sbjct: 1671 RCGMIYLEPSQLGWEPLVSSWLNSLKG-PLCEPEYQALLR-------GLFAWLIPPSLNQ 1722
Query: 2416 QRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLR--CLGSLFSMLHQACRNVAQYN 2473
+ + + Y T + K L F++ + L+ C F + QAC
Sbjct: 1723 RVELFQLNYLYTTIVSKILKIL-ITFRISNYFKYVPLKTQCTFIKFFLHQQAC------- 1774
Query: 2474 ANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRI-----TTVPLPT 2528
+++++WS+ G R +IR I P+P
Sbjct: 1775 --------------------FIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPD 1814
Query: 2529 AP---NIPIID--------YEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRH 2577
+ P + YE+ G W W + + ++ D++VPT+DT+R+
Sbjct: 1815 SVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRY 1874
Query: 2578 EALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDME---VVGLNFSSATTPELLLKT 2634
L+ + KPL+ GP G+GK++ + L + + +N S+ T+ +
Sbjct: 1875 TFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNI 1934
Query: 2635 FDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYR 2694
+ RR GV P +GK ++F D++N+P ++KYG Q I +RQ + G +Y
Sbjct: 1935 IMARLDKRR--KGVFGPP--MGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYD 1990
Query: 2695 TSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRA 2754
D + + L I+ + A PP GR P++ R +RH + ++ ++ +I+ +
Sbjct: 1991 LKDTSKITLVDIELIAAMGPP-GGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAF 2049
Query: 2755 MLR---LIPSLRTYAEPLTAAMVEFYTMSQER-FTQDTQPHYIYSPREMTRWVRGIFEAL 2810
LR P + +E Y S E T+ HY ++ R+ +R +RG
Sbjct: 2050 YLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIE 2109
Query: 2811 RPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRP 2870
R +IR++ HE LR+F DRL+ D++RRW + TV HF S
Sbjct: 2110 RD-AVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKE-------SFH 2161
Query: 2871 ILYSNWLSKDYIPVDQEELR-----DYVKARLKVFYEEELDVP----------------- 2908
++S+ L K PV +E+LR DY+ L+ +++P
Sbjct: 2162 SIFSH-LRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYN 2220
Query: 2909 --------LVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQ 2960
LV+F VL+H+ RI R+ +Q G+ LL+G+ G+G+ +L+R M + ++Q
Sbjct: 2221 QTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQ 2280
Query: 2961 IKVHRKYTGEDFDEDLRTVL 2980
++ + Y ++ ED+++ +
Sbjct: 2281 PEISKSYGMNEWREDMKSFI 2300
Score = 201 bits (511), Expect = 1e-50
Identities = 199/818 (24%), Positives = 348/818 (42%), Gaps = 74/818 (9%)
Query: 3854 QRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNE 3913
+RL + + + R + +D + F+ LL L E Y E L G
Sbjct: 2318 KRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARK-EIEYQ-ELMFLLTGGV 2375
Query: 3914 IVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYL 3973
+ SA P L + E + R S PAF+ L + E W + ++ P+
Sbjct: 2376 SLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGL--RQHFCEHIYEWREIYDSKE--PHN 2431
Query: 3974 WSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGT 4033
P + ++++++ RPD++ +V+ LG+ F+ P DLT
Sbjct: 2432 AKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVE--PPPFDLTKSY-L 2488
Query: 4034 EVKPNTPVLMCSVPGYDASGHVEDLAAEQN---TQITSIAIGSAEGFNQADKAINTAVKS 4090
+ P++ PG D + A +++ + +I++G +G A K I A++
Sbjct: 2489 DSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQG-PIAAKMIKAAIEE 2547
Query: 4091 GRWVMLKNVHLAPGWLMQLEKKLHSLQPHAC---FRLFLTMEINPKVPVNLLRAGRIFVF 4147
G WV L+N HLA W+ LEK C FRL+LT + K PV +L+ G
Sbjct: 2548 GTWVCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTN 2607
Query: 4148 EPPPGVKANMLRTFSSIPVS-----RICKSPNER-ARLYFLLAWFHAIIQERLRYAPLGW 4201
EPP G++ N+L+++ + PVS + C+ +L F + +FHA++QER ++ PLGW
Sbjct: 2608 EPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGW 2667
Query: 4202 SKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFD 4261
+ Y F ESDLR + + ++++ D IP+ A+ L + YGGRV +++D
Sbjct: 2668 NIPYGFNESDLRISIRQLQLFINEY---------DTIPFEAISYLTGECNYGGRVTDDWD 2718
Query: 4262 QRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWL 4321
+RLL T L + ++ K + P E+++++++ LP TQ P
Sbjct: 2719 RRLLLTMLADFYNLYIVENPH---YKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIF 2775
Query: 4322 GLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLH 4381
GL N + ISK L+ E L K+T ++D + L
Sbjct: 2776 GLHENVD-----------ISKDLQQTKTLFESLLLTQGGSKQTGASGSTD------QILL 2818
Query: 4382 TTASNWLHLIPQTLS---HLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVC 4438
+ L+ +P L++ ++ + +E++ L+ +R L D+ +
Sbjct: 2819 EITKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAI 2878
Query: 4439 EGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAAS 4498
+G + L L L+ G +P W+ + P+ + +++DF R+ LQ+ +
Sbjct: 2879 KGVVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSG-- 2936
Query: 4499 GGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGA-TLDACS 4557
K L G F +A++T Q A+ + ++ L E V S + T
Sbjct: 2937 ------KPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTSPEDG 2990
Query: 4558 FGVTGLKLQGATCNNNKLSLSNAISTAL-PLTQLRWVKQTNTEK--KASVVTLPVY---- 4610
+ GL L GA + L+ L L + W+K T + K+ P+Y
Sbjct: 2991 VYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSE 3050
Query: 4611 ----LNFTRADLIFTVDFEIATKEDPRSFYERGVAVLC 4644
L+ T F + + T + R + +RGVA+LC
Sbjct: 3051 RKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLC 3088
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 539 bits (1389), Expect = e-152
Identities = 398/1664 (23%), Positives = 754/1664 (45%), Gaps = 163/1664 (9%)
Query: 2936 IGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMD 2995
IG+ G GK T + ++ +Y++ + K +F E + V +G K + ++
Sbjct: 2665 IGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHAGLKGKPTVLMVP 2724
Query: 2996 ESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFT 3055
N+ FLE +N ++++G +P LFE E ++ + + ++ G M D+ + L +F
Sbjct: 2725 NLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHM-DNRQSLLSFFQ 2783
Query: 3056 SQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDL 3115
++ +NLH+ M+P + P++ + C ++W+ W EAL V F
Sbjct: 2784 KRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEALLIVANSFLK---- 2839
Query: 3116 EKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRH 3175
EK N+ + + +E + +CV +H+++ N + + GR TP
Sbjct: 2840 EKVNFENRENL-------------KEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNS 2886
Query: 3176 YLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAA 3235
YL F+ +A++ + E++ ++ ++GL I E V E++ +L I ++E K
Sbjct: 2887 YLQFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKE 2946
Query: 3236 ANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNA 3295
++K+ KD Q EK +++ ++ +E + ++ ++ D +L V PA +A A
Sbjct: 2947 TETLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVA 3006
Query: 3296 VKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFS 3355
+ ++ K + E+R PP V + ++C+LL + +W + ++ F+ ++N
Sbjct: 3007 LNALDKADVAELRVYTRPPFLVLTVMNAVCILL-QKKPNWATAKLLLSETGFLKKLINLD 3065
Query: 3356 AEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNE 3415
+ I D + K+KK ++ P +N ++ S+AC + +W IA NY ++ K V P + +
Sbjct: 3066 KDSIPDKVFVKLKK-IVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKVVGPKQIQ 3124
Query: 3416 LQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRS 3475
+ + ++ K +Q+ E ++ ++ +E + + Y ++E Q + + +
Sbjct: 3125 VAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRKTMASRRFQCA 3184
Query: 3476 TALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHH 3535
+ LL L E+ RW++T N++ I GD LLSAA I Y+G + RQ + W
Sbjct: 3185 SVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEFRQLIVNKWETF 3244
Query: 3536 LQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQ 3595
+ I + + + ++ E RW LP ENAI++K ++PL+IDP Q
Sbjct: 3245 CIENGISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNGQQWPLLIDPHRQ 3304
Query: 3596 ATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVR 3654
A ++I + + ++ + S D + K +E+A++ G +L+Q++ E+ P L +L +++
Sbjct: 3305 AHKWI-RQMEGSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLAPGLKAILKKDIY 3363
Query: 3655 RTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLN 3714
+ G I +GD + + + +F ++LST F P + + VT +NFTVT LQ Q L+
Sbjct: 3364 QKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFTVTFQGLQDQLLS 3423
Query: 3715 EVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLK 3774
V+ E P ++++RS LL+ + L +LE+ L L + G ILDDD I+ TL K
Sbjct: 3424 TVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDDKIVDTLRKSK 3483
Query: 3775 REAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLD 3834
+ E+++++E T E++ + + YLP++T + +YF + L QI+++YQ+SL +F
Sbjct: 3484 MTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYMYQFSLDWFHQ 3543
Query: 3835 IY------------HNV---------------LYENPNL---KGVTDH--TQRLSIITKD 3862
++ H+ + + PNL K + D + ++TK
Sbjct: 3544 VFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHIKSAIDMLTKS 3603
Query: 3863 LFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTY--------DAEFQHFLRGNEI 3914
+F+V V+ + ++D + F+ L + ++ + E+ FL +
Sbjct: 3604 IFKV----VSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLYSGIL 3659
Query: 3915 V--------------LSAGSTPRIQGLTVEQ------------------AEAVVRLSCLP 3942
+ G + +Q L+ + + +S
Sbjct: 3660 INIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSLLSNVSQWD 3719
Query: 3943 AFKD------LIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIG------QAIHRL 3990
FK+ LI+ + E + ++ PE+T ++ET PI + RL
Sbjct: 3720 TFKNSKAVYSLISTPFSSENASLEENTKPPEETELLNENKET-CNPINFPWEKLTSFQRL 3778
Query: 3991 LLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYD 4050
+L++ RP+ L F++ +G ++ L + G+ + TP+++ G D
Sbjct: 3779 ILVKVLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAY-KGSNAR--TPLILIQTHGID 3835
Query: 4051 ASGHVEDLAAE---QNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLM 4107
+ + A E +T I++G + D + K+ +WV L+N HLA ++
Sbjct: 3836 LTNILLRFAQELKGTTHHVTIISLGRDQAAKAEDLILKALTKTQQWVFLQNCHLATSFMP 3895
Query: 4108 QLEKKLHSL-QPHAC----FRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFS 4162
+L + S P+ FRL+L+ + P+ +L+ G E P G+K+N+L+TF
Sbjct: 3896 RLCTIVESFNSPNVTIDPEFRLWLSSKSYSSFPIPVLKKGLKIAVESPQGLKSNLLQTFG 3955
Query: 4163 SIPVSRICKSPNER-------ARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSA 4215
+ + E +L F L +F+A+I ER Y LGW+ Y+F SDL A
Sbjct: 3956 CTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSSDLGVA 4015
Query: 4216 CDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTT 4275
L+++ +G+ +IS W AL+ L+ + IYGGRV + +D+R L T L +
Sbjct: 4016 IKV----LENSLRGQPSIS-----WQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNP 4066
Query: 4276 RSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQ 4335
+F + ++++ ++ LPD P LG+ A R TQ
Sbjct: 4067 EVLKDDFSFSRSAS------------IKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQ 4114
Query: 4336 GVDMISKMLKMQMLEDEDDLAYAETEKK------------TRTDSTSDGRPAWMRTLHTT 4383
G I ++ MQ +L + K R T + + T T
Sbjct: 4115 GEKFIENLIAMQPKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIAVGTPSTL 4174
Query: 4384 ASNWLHLIPQTLS-HLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKK 4442
S I ++LS +LK I L F ++E+K KLL + + L D+ +G+
Sbjct: 4175 KSMMSSSIWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAIKGEI 4234
Query: 4443 KQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERI 4486
T L + N + +P W + + + W+ D +R+
Sbjct: 4235 ILTQELEEIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRL 4278
Score = 536 bits (1381), Expect = e-151
Identities = 358/1160 (30%), Positives = 579/1160 (49%), Gaps = 153/1160 (13%)
Query: 1316 EERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWV-------SVQPRKLRQNLDALLN 1368
EE Q+ L E+ D++G + K+WE ++ K W S+ +++N+ L++
Sbjct: 979 EEITQIVLSEISDIEGDLTLRKKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMH 1038
Query: 1369 QLKSFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE 1428
+ L + +++++ + + ++I L + LK RHW+ L + + + + +
Sbjct: 1039 IISVLEKGLPKSDMVTHLKQVVTEFKQELPIIIALGNPCLKPRHWEALQEIIGKSVPLDK 1098
Query: 1429 -LTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCR-- 1485
+ + + + + E + D+ A E ALE+ L +I + WNT L L+ + +
Sbjct: 1099 NCKVENLLALKMFQYENEINDMSTSATNEAALEKMLFKIIDFWNTTPLPLILHHTEIYSI 1158
Query: 1486 -LIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRW 1544
+I DD+ +++E ++ +K SP+ ++ W+ L + W++ QR W
Sbjct: 1159 FIIPSIDDISAQLEESQVILATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEEWMNCQRNW 1218
Query: 1545 VYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERL 1604
+YLE +F S++I+ LP ET+ F + + + +M K+ + + GV L+
Sbjct: 1219 LYLEPVFH-SSEIRRQLPAETELFSQVISMWKKIMSKIQNKQNALQITTSAGVLEILQNC 1277
Query: 1605 ADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSI 1664
L I+K+L +YLE +R FPRFYF+ + +LL+I+ +S+N +Q H K F + +
Sbjct: 1278 NIHLEHIKKSLEDYLEVKRLIFPRFYFLSNAELLDILADSRNPESVQPHLVKCFENIKQL 1337
Query: 1665 ILNEDN---SVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESV 1721
++ + + V + S EGE ++ P I + +WL VEK M L K
Sbjct: 1338 LIWKQDIGPPAVKMLISAEGEGLVL--PKKIRVRSAVEQWLVNVEKSMFDVLKK------ 1389
Query: 1722 TEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSV 1781
YI Y L+ S + +++ V++ +SS L V
Sbjct: 1390 --------------ERYI-----YNIILLFQSQIMFYNDCVKSFVSSYS----REKLEKV 1426
Query: 1782 LSNVEVTLNVLADSVLMEQPPLRRRK-LEHLITELVHQRDVTRSLIKSKIDNAKSFEWLS 1840
+ + L +AD V+++ R + L L+ VH RD+ +L+ I NA+ FEW
Sbjct: 1427 HAGLMCHLEEVADLVVLDTSNSRTKAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTR 1486
Query: 1841 QMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARL 1900
+++ ++ KQ + + NA F YG+EYLG +LV TPLTDRC+LT+ +AL L
Sbjct: 1487 HLQYKWNEKQ----KLCYVSQGNASFTYGYEYLGCTSRLVITPLTDRCWLTLMEALHLNL 1542
Query: 1901 GGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEF 1960
GG P GPAGTGKTE+VK L LG+ +VFNC E D++ + + F GL Q GAW CFDEF
Sbjct: 1543 GGCPAGPAGTGKTETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEF 1602
Query: 1961 NRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNP 2020
N ++ +LS ++ Q+ I+ A D SA E K+++++ A+FITMNP
Sbjct: 1603 NLIDLEVLSVIASQILTIKAA--------KDNYSARFVLE--GKEIRINMSCAVFITMNP 1652
Query: 2021 GYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQL 2080
Y G LPDNLK LFR +AM P Q+IA+++L+S GF++A L+ K+ ++L +QL
Sbjct: 1653 RYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILFSFGFKSANSLSGKLTNLYELARKQL 1712
Query: 2081 SSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQS 2140
S Q HY+FGLR+LK VL+ AG KRE + + E + E I+I++
Sbjct: 1713 SQQDHYNFGLRSLKIVLIMAGTKKRE------------FKCLSEAD------ETLIVIEA 1754
Query: 2141 VCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVG 2200
+ E +PK ED+PL +++ D+FP V + AL + + Q++ L ++
Sbjct: 1755 IREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLGLQNWSSQK-- 1812
Query: 2201 GMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVE--GVAH------ 2252
EK++Q Y Q+ G+M+VGP+G GK+ R+L KAL L + VA
Sbjct: 1813 ----EKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAERKSASK 1868
Query: 2253 -----------IIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKII------------- 2288
+++PK ++ LYG LDPNT EWTDGL + +R +
Sbjct: 1869 ISERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTKKDID 1928
Query: 2289 -------------------------DSVRGELQK-----------RQWIVFDGDVDPEWV 2312
D++ E++K QWI+ DG VD WV
Sbjct: 1929 LRLKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPVDTFWV 1988
Query: 2313 ENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTD 2372
ENLNSVLDD + L L N ER++L +R++FEV +L A+ ATVSRC MV+ L +
Sbjct: 1989 ENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVDLGWE 2048
Query: 2373 MIFNNFLARLRSIPLDEGED 2392
++L + I G D
Sbjct: 2049 PYVKSWLLKTSKIISQSGVD 2068
Score = 85.9 bits (211), Expect = 9e-16
Identities = 60/227 (26%), Positives = 114/227 (50%), Gaps = 25/227 (11%)
Query: 2621 NFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVI 2680
N ++A T E++LK RRT + + AP +++F D++N+P D YG Q +
Sbjct: 2435 NVTAAKTKEMILKKL-----IRRTKD-TLGAPKN--NRILIFIDDMNMPVSDMYGAQPPL 2486
Query: 2681 SFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG 2740
IRQ+++ GG Y T TW ++ + V AC P + +S R L+H ++ + +P
Sbjct: 2487 ELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVN----DISPRLLKHFSMLVLPHPS 2542
Query: 2741 PASLTQIYGTFNRAMLRLIPSLRTYA--------EPLTAAMVEFYTMSQERFTQDTQPHY 2792
L I+ +A L + S+ + + ++ ++ ++ + Q T+ HY
Sbjct: 2543 QDILCTIF----QAHLGIYFSINNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPTKCHY 2598
Query: 2793 IYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVE 2839
+++ R+M + + G+ +A R + E ++ HEA R+F DRL++
Sbjct: 2599 MFNLRDMFKLLLGLLQADRTVVN-SKEMAALLFVHEATRVFHDRLID 2644
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 229 bits (584), Expect = 5e-59
Identities = 209/856 (24%), Positives = 382/856 (44%), Gaps = 88/856 (10%)
Query: 3815 MESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQR---LSIITKDLFQVAFNRV 3871
M L +IH +YQ+SL+ F +++++ + D + R ++I F V +
Sbjct: 1 MNDLSKIHPMYQFSLKAF-----SIVFQKAVERAAPDESLRERVANLIDSITFSV-YQYT 54
Query: 3872 ARGMLHQDHITF-AMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVE 3930
RG+ D +T+ A L +I L + E LR + G+ ++ L+ +
Sbjct: 55 IRGLFECDKLTYLAQLTFQILL---MNREVNAVELDFLLRSP---VQTGTASPVEFLSHQ 108
Query: 3931 QAEAVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSSPE-QTVPYLWSEETPATPIGQAIH 3988
AV LS + F +L ++ + + +++S PE + +P W +T A+
Sbjct: 109 AWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKT-------ALQ 161
Query: 3989 RLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPG 4048
RL +++A RPDR+ FV LG + ++ + LD E P TP+ PG
Sbjct: 162 RLCMLRAMRPDRMTYALRDFVEEKLGSKY--VVGRALDFATSF-EESGPATPMFFILSPG 218
Query: 4049 YDASGHVEDLAAE-----QNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAP 4103
D VE + N ++++G + A+ A++ A K G WV+L+N+HL
Sbjct: 219 VDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEV-VAEAALDLAAKKGHWVILQNIHLVA 277
Query: 4104 GWLMQLEKKL--HSLQPHACFRLFLTMEINPK-----VPVNLLRAGRIFVFEPPPGVKAN 4156
WL LEKKL HS H FR+F++ E P +P +L EPP G+ AN
Sbjct: 278 KWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHAN 337
Query: 4157 MLRTFSSIPVSRI--CKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRS 4214
+ + + + C E + F L +FHA++ ER ++ P GW++ Y F DL
Sbjct: 338 LHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTI 397
Query: 4215 ACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFT 4274
+ + + +L+ A K+P+ L+ L + +YGG + +++D+RL T+L
Sbjct: 398 SVNVLYNFLEANA---------KVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIR 448
Query: 4275 TRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTT 4334
+ E LA +P + + Q+++ ++P GL NAE LT
Sbjct: 449 PEMLEGELSLA------PGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQ 502
Query: 4335 QGVDMISKMLKMQMLEDE-DDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQ 4393
+ +L++Q + + D A A E+K + A + + ++ + IP+
Sbjct: 503 TSEKLFRTVLELQPRDSQARDGAGATREEKVK---------ALLEEILERVTDEFN-IPE 552
Query: 4394 TLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLIN 4453
++ ++ + P +E L +++++ L ++ +G+ T+++ L N
Sbjct: 553 LMAKVEE-----RTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQN 607
Query: 4454 ELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGG 4513
L ++P SW+ P+ + W D RIK+L+ A G + + V L G
Sbjct: 608 ALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELE------AWTGDFTMPST-VWLTG 660
Query: 4514 LFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDAC---SFGVTGLKLQGATC 4570
F P++++TA Q A+ N W L+++ L+ ++T + + GL ++GA
Sbjct: 661 FFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACW 720
Query: 4571 NNNKLSLSNA-ISTALPLTQLRWVKQTNTEKK--ASVVTLPVYLNFTRADLIFTVDFEIA 4627
+ ++ A + P + ++K +K+ SV + PVY R + F +
Sbjct: 721 DTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGP-TYVWTFNLK 779
Query: 4628 TKEDPRSFYERGVAVL 4643
TKE+P + GVA+L
Sbjct: 780 TKENPSKWVLAGVALL 795
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 218 bits (556), Expect = 8e-56
Identities = 373/1729 (21%), Positives = 679/1729 (39%), Gaps = 271/1729 (15%)
Query: 1332 VWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASY-EFVQRLL 1390
+W + E I + K + P ++ + L + L ++ + R+L
Sbjct: 1021 IWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRIL 1080
Query: 1391 KGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWV--VSELTLGQIWDVDLQKNEAIVKD 1448
+ L+ +L S + + + L++ L + + + LTLGQ+ L + +
Sbjct: 1081 GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQ 1140
Query: 1449 VLLVAQGEMALEEFLKQIREVWNTYELDLVNY------------QNKCRLIRG------- 1489
V + +E +++++ W +L L+N+ ++K +++R
Sbjct: 1141 VWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVD 1200
Query: 1490 ----------WDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWID 1539
+ +L + ++E + +S + + AL W ++ + AL +VW+
Sbjct: 1201 KDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLT 1260
Query: 1540 VQRRWVYLEGIFTGSADIKHLLPVE--TQRFQSISTEFLALMKKVSKSPLVMDVL----- 1592
Q++W++L + ++K P RF+ + ++ LM+ P+V+ ++
Sbjct: 1261 FQQKWIFLNKVLH---EMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAE 1317
Query: 1593 -----NIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNV 1647
Q +Q+ L+ + L I +L L + FPR +F+ D +L+ ++
Sbjct: 1318 RSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLES 1377
Query: 1648 AKLQKHFKKMFAGVSSIILN-----EDNS-------------VVLGISSREGEEVMFKTP 1689
+ Q ++ F V ++ E N+ L + GEEV + P
Sbjct: 1378 CEAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGP 1437
Query: 1690 VSITEHPKINEWLTLVEKEMRVTLAKLLAESVTE-----------VEIFGKATSIDPNTY 1738
+ + HP + +WL +EK +R+ L +L V ++ K + Y
Sbjct: 1438 LPL--HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLY 1495
Query: 1739 IT-WIDKYQA---QLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVL-- 1792
+ WID QA Q V+++ ++ W +E AL G A + + +EV +N +
Sbjct: 1496 VQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWG---TLAMVSMHMRKLEVLVNFMRA 1552
Query: 1793 --ADSVLMEQPPLRRRKL-EHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFD-- 1847
A P +R+ L L+ V RD+ + L + ++ + F W+ Q++++
Sbjct: 1553 QRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSP 1612
Query: 1848 ---PKQTDVLQQLS---------------IQMANAKFNYGFEYLGVQDKLVQTPLTDRCY 1889
PK LQ L I + F Y +EYLG + + + L +R
Sbjct: 1613 HIIPKSP--LQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPA 1670
Query: 1890 LTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLC 1949
L + ALE G+ GP G GK V +L LGR +++ C + Q + G
Sbjct: 1671 LVLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGAL 1730
Query: 1950 QVGAWGCFDEFNRLEERMLSAVSQ---QVQCIQEALREHSNPNYDKTSAPITCELLNKQV 2006
Q GAW ++ ++L +LSA+ Q ++ + L + ++ N T P +LL
Sbjct: 1731 QGGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRN-TSTIDPTQPQLLGSSF 1789
Query: 2007 KVSPDMAIFITMNPGY-------AGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGF 2059
+++ + GY A S +P NL L R +A+ PD + +A++ L G
Sbjct: 1790 FEKHHVSVRL----GYGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGM 1845
Query: 2060 RTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERG 2119
R A +A ++ FF L E +S L LK +L + I+ + KEE
Sbjct: 1846 RDAFQMATRLSKFFSLERELVSGP--LPCRLPLLKQIL-------EDTIRTLNVTKEE-- 1894
Query: 2120 EAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYH--RGEMTA 2177
C+ E+ LL S L + G+ H RG + A
Sbjct: 1895 --------------------PKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNLRGLLCA 1934
Query: 2178 LREELKKVCQEMY-------LTYGDGEEVGGMWVEKVL----QLYQITQINHGLMMVGPS 2226
L +V E L + ++VG +L QL Q G++++GP+
Sbjct: 1935 LFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPA 1994
Query: 2227 GSGKSMAWRVLLKALERLEGVEG----------VAHIIDPKAISKDHLYGTLDPNTREWT 2276
GSGK+ W L K RL +E + H+ P +S G L+ + W
Sbjct: 1995 GSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLY-PSGLSPQEFLGWLEGSC--WH 2051
Query: 2277 DGLFTHVLRKIIDSVRGELQKRQ---------WIVFDGDVDPEWVENLNSVLDDNKLLTL 2327
G+F VLR QKRQ WI+ DG + W++++ +L + L+L
Sbjct: 2052 HGIFPKVLR-AAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQLSL 2110
Query: 2328 PNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSED-----VLSTDMIFNNFLARL 2382
P+G++++ PP ++ EV D + V C +VW + +LS M + RL
Sbjct: 2111 PSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQTWQCILSALMASLPYEYRL 2170
Query: 2383 RSIPLDEGEDEAQRRRKGK-EDEGEEAASPMLQI--QRDAATIMQPYFTSNGLVTKALEH 2439
+ + E A+ + S +LQ+ Q+ + + ++ L+
Sbjct: 2171 QHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSMARILHSLLDL 2230
Query: 2440 AFQLEHIM-----DLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYL 2494
+L+ DL+ + F + N +Q +++ D P + + + +L
Sbjct: 2231 HLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSD--DVPDKCREHLLAVSSFL 2288
Query: 2495 VYAILWSLSGDSRLKMRAELGEYIR----RITTVPLPTAPNIPIIDYEVS-ISGEWSPWQ 2549
+A++W + +IR R++ P P P+ + D VS G P+
Sbjct: 2289 -FALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEP-PPSALVFDLHVSPEDGTLVPFT 2346
Query: 2550 AKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSAL 2609
+ + +H P++ T R ++ L+ +P++L G +GK + F +
Sbjct: 2347 GQY----LSSHIKGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGK--SAFVEV 2400
Query: 2610 RALPD----MEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLF-CD 2664
P + FSS+ LL + + P Q K +LF +
Sbjct: 2401 LVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQP-----GHHQDSKPSLLFLLE 2455
Query: 2665 EINLPDMD-KYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQ-FVGACNPPTDPG--R 2720
+++L D + Q V+ +RQ ++ G Y S ++L+ +Q V T PG
Sbjct: 2456 DLHLATSDPEKSCQPVLETLRQAMD-GTVYAHST---LELQTLQPTVNFLATVTVPGYCE 2511
Query: 2721 KPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSL---RTYAEPLTAAMVEFY 2777
+PL R R V+ ++ A+L + + +A L PS+ R A L A VE +
Sbjct: 2512 RPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRASVEAW 2571
Query: 2778 TMSQERF-TQDTQPHYIYSPREMTRWV------------RGIF------EALRPLETL-- 2816
F PHY +S ++ + RG E LR + L
Sbjct: 2572 EAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRG 2631
Query: 2817 -------PVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHF 2858
++R+W HEA R F DRL ER + + + VA F
Sbjct: 2632 TCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
Score = 95.5 bits (236), Expect = 1e-18
Identities = 163/761 (21%), Positives = 294/761 (38%), Gaps = 123/761 (16%)
Query: 2904 ELDVPLVLFNEVLDHVLRIDRIFRQPQGH-LLLIGVSGAGKTTLSRFVAWMNGLSVYQIK 2962
+L L + + HV R+ R+ +P+ H LLL G G G+ T + S+ Q
Sbjct: 2857 KLSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLAS-----SICQAH 2911
Query: 2963 VHRKYTG--EDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGL 3020
+G E + LR +G ++ +A ++ +D L R+ L +G PG
Sbjct: 2912 FFHLPSGSEEAILQCLRDASWHAGMLSQPVALLVPSG--VDLTTLHRLLALATSGSFPGQ 2969
Query: 3021 F-EGDEYATLMTQCKEGAQKEGLMLDSH---EELYKWFTSQVIRNLHVVFTMNPSSEGLK 3076
+ E D + + E +E L + + E + + F QV +LH+ F + + K
Sbjct: 2970 YTEAD-----LDRIGEHLPRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIG-DKQAHK 3023
Query: 3077 DRAATSPALFNRCV------LNWFGDWSTEALYQVGK---EFTSKMDLEKPNYIVPDYMP 3127
+T LF R + ++ + W AL +V + E + L+ ++ PD
Sbjct: 3024 QLPST---LFLRLLQLATASIDRYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQA 3080
Query: 3128 VVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLF 3187
+P I S H+ L A +TP+ +LDF++ + L
Sbjct: 3081 ----SIPSVAKAMALIHLSATHYHEHLCPA----------LPLVTPKTFLDFLDTFLML- 3125
Query: 3188 HEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKD- 3246
+QQ L KIK +V+ +LR+ +E D L++ +KD
Sbjct: 3126 --------QQQTIL-----KIKNKAQRVQNALENLRMLIKEHGTHANLIFD-LEQQLKDS 3171
Query: 3247 -------QQEAEKKKVMSQEIQEQLHKQQEVIADK-------QMSVKEDLDKVEPAVIEA 3292
QQ+ E+ K++ ++ E+ Q+ +I + Q + L+++ A +E
Sbjct: 3172 GKSLSMFQQQLEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAFLEQMSKAFLEP 3231
Query: 3293 QNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIV 3352
+ ++ E+RS PP +V +++C L T W + ++ E+F +V
Sbjct: 3232 ---LSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHHET-GWASAKQLLCTEDFYQELV 3287
Query: 3353 NFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPL 3412
F E+I+D+ K+ + P + + S + W A L+Y R P
Sbjct: 3288 FFPKEKITDSELIKLHL-ILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPT 3346
Query: 3413 RNELQKLEDDAKDNQQKANEVE-QMIRDLEASIARYKEEYAVLISEAQA----IKADLAA 3467
LQ++E Q + + Q LE ++A K ++ +AQA + L+
Sbjct: 3347 DLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAK-----MVEDAQASHNCVAKTLSQ 3401
Query: 3468 VEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQN 3527
+ + +L W + K + T+ GD LL +A I Y G F RQ
Sbjct: 3402 AQCGQYHKWPMKAALLTPMRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQE 3461
Query: 3528 LFTTW--------------------SHHLQQANIQFRTDIART-------EYLSNADERL 3560
L W + +I + + T LS+ E+
Sbjct: 3462 LLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQY 3521
Query: 3561 RWQASSLPADDLCTENAIMLKRFN-----RYPLIIDPSGQA 3596
+W + P ++L+ R+PL++DPS +A
Sbjct: 3522 QWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEA 3562
Score = 40.0 bits (92), Expect = 0.054
Identities = 124/598 (20%), Positives = 213/598 (35%), Gaps = 82/598 (13%)
Query: 3938 LSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFR 3997
L LP F L A + W S TV L P + +L+L + R
Sbjct: 3993 LELLPPFVGLCASLAGHSS--AWQAYLSLSSTV--LGPAPGPGPEPLSLLQKLILWRVLR 4048
Query: 3998 PDRLLAMAHMFVSTNLGESFMSIMEQP-LDLTHIVGTEVKPNTPVLMCSVPGY-DASGH- 4054
P+ L F ++ LG P + H T+ +++ PG+ A+ H
Sbjct: 4049 PECLAGALADFTTSLLGRPLDENTYAPTMPFKHSQATQPM----LILLPPPGHPSATLHP 4104
Query: 4055 ---VEDLAAEQNT---QITSIAIGSAEGFNQADKAINT---AVKSGRWVMLKNVHLAPGW 4105
++ LAA+ Q+ IA+GS E ++ ++T A+ G W++L N HL P W
Sbjct: 4105 LTVIQKLAAKYQQGQKQLQVIALGS-EAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHW 4163
Query: 4106 LMQLEKKLHSL-----------------QP--------HACFRLFLTM--EINPKVPVNL 4138
+L + L L QP H FRL+L + E + +P +
Sbjct: 4164 PKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPA-V 4222
Query: 4139 LRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAP 4198
L + VF ++L + + P +A LL H ++ R Y
Sbjct: 4223 LTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQALPLLLL---HGLLLHRQLYGT 4279
Query: 4199 LGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDN 4258
+ + + + L T D + P +A++ L A YGG + +
Sbjct: 4280 RLQAHRGRWSQVTLTQVLQTQDQLWASLSN----------PRAAMQELAASVFYGGPLGD 4329
Query: 4259 EFDQRLLNTFLERLFTTRSFD-----SEFKLACKVDGHKDIQMPDGIRREEFVQWVELLP 4313
D+ L + + + S + L + +++ D + E + LLP
Sbjct: 4330 TEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAM--AECKAQMHLLP 4387
Query: 4314 DTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQML---EDEDDLAYAETEKKTRTDSTS 4370
P GL + LL Q ++S + + + E AE + R +
Sbjct: 4388 SPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQVN 4447
Query: 4371 DGRPAWMRTLHTTASNWLHLIPQTLSHLKRTV--ENIKDPLFRFFEREVKMGAKLLQDVR 4428
R L + H+I Q S +V N + PL E E ++L+ ++
Sbjct: 4448 -------RRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQ 4500
Query: 4429 QDLADVVQVCEGKKK-QTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSER 4485
+DL ++Q +G + + + L G LP W + W+ S R
Sbjct: 4501 RDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRR 4558
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 55.8 bits (133), Expect = 1e-06
Identities = 68/339 (20%), Positives = 159/339 (46%), Gaps = 35/339 (10%)
Query: 3191 RSELEEQQMHLNVGLRKI-KETVDQVEELRR---DLRIKSQELEVKNAAANDKLKKMVKD 3246
++E+E ++ HL + K+ KE D VE R +L+ + E + KN ++++ +K+
Sbjct: 936 KNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKE 995
Query: 3247 QQ-EAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDK---VEPAVIEAQNAVKSIKKQ 3302
+ EAEK ++ + ++Q+++ +E + D Q + E L K +E + + + +++ K
Sbjct: 996 KTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEA--KS 1053
Query: 3303 HLVE-----VRSMANPPAAVKLALES-------ICLLLGESTTDWKQIRSIIMRENFIPT 3350
HL + V+ M + + +++ LE + + S +Q+R+ +++E
Sbjct: 1054 HLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQER--AA 1111
Query: 3351 IVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVE 3410
+ ++IS + K K+ + + +Y S G +V+ + A++ R+E
Sbjct: 1112 RQDLECDKISLERQNKDLKSRIIHLEGSYR-----SSKEGLVVQ---MEARIAELEDRLE 1163
Query: 3411 PLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEA 3470
+ L+ + ++K E+ + D S+ K++ ++ + +A+K + E
Sbjct: 1164 SEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRL---KAMKRQVEEAEE 1220
Query: 3471 KVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLL 3509
+++R + K L E E +E + Q++++ D L
Sbjct: 1221 EIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRL 1259
Score = 50.4 bits (119), Expect = 4e-05
Identities = 76/393 (19%), Positives = 162/393 (41%), Gaps = 71/393 (18%)
Query: 3178 DFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAAN 3237
D NL EK L+ + G + + +V +DL + +L ++ A
Sbjct: 572 DATKRKVNLVFEKIQTLKSRAAGSAQGNNQACNSTSEV----KDLLEQKSKLTIEVAELQ 627
Query: 3238 DKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAV---IEAQN 3294
+L+ VK+QQ ++++ + E+L Q ++ ++++ L++ E + +E
Sbjct: 628 RQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELF 687
Query: 3295 AVKSIKKQHLVEVRSMANPPAAVKLALESIC--------LLLGESTTDWKQIRSIIM--- 3343
VK ++QH E+R + + + + L+S L+ E + ++ +++
Sbjct: 688 QVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKE 747
Query: 3344 --------RENFIPTIVNFSAEEIS--DAIREKMKKNYMSNPSYNYEIVNRASLACGPMV 3393
RE + + EE+S D +K+K+ Y + E V A+ +
Sbjct: 748 EQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLA 807
Query: 3394 KWA-IAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKE--- 3449
+ ++ + A RV+ L+ E +KL+ +++ +++ ++++ I DL+ A+ KE
Sbjct: 808 SRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLK 867
Query: 3450 ------------------EYAVLISEAQAIKADLAAVEAKVNRSTALLKSLS-------- 3483
E +S +A++ +L A + ++++T K LS
Sbjct: 868 KYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESE 927
Query: 3484 -----------AERERWE--KTSETFKNQMSTI 3503
E ERW KT E + +M+ I
Sbjct: 928 QKEQLRRLKNEMENERWHLGKTIEKLQKEMADI 960
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 53.9 bits (128), Expect = 4e-06
Identities = 114/647 (17%), Positives = 260/647 (40%), Gaps = 73/647 (11%)
Query: 3189 EKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQ- 3247
E+ + EE L RK+++ ++++ DL + ++E + A +K+K + ++
Sbjct: 930 ERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMA 989
Query: 3248 ------QEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKK 3301
+ K+K QE +Q + DK ++ + K+E V + + +++ KK
Sbjct: 990 GLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKK 1049
Query: 3302 QHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEE--- 3358
+ R+ +KLA ESI + E +Q+ + ++ F + + E+
Sbjct: 1050 LRMDLERAKRKLEGDLKLAQESIMDIENEK----QQLDEKLKKKEFEISNLQSKIEDEQA 1105
Query: 3359 ISDAIREKMKKNYMSNPSYNYEI-VNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQ 3417
+ +++K+K+ EI RAS A A+ +D+ + +E + L+
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASR--------AKAEKQRSDLSRELEEISERLE 1157
Query: 3418 K----LEDDAKDNQQKANEVEQMIRDL-------EASIARYKEEYAVLISE--------- 3457
+ + N+++ E ++M RDL EA+ A ++++A ++E
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQ 1217
Query: 3458 --AQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIA 3515
Q ++ + + ++ +++ + ++++S + EK T ++Q+S +
Sbjct: 1218 RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK----------- 1266
Query: 3516 YAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTE 3575
+ +QQ N T LQ + +F + E L + R + QA + ++L +
Sbjct: 1267 -SKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGK-QAFTQQIEELKRQ 1324
Query: 3576 NAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLV 3635
+K N + S + + +Y++ + ++ L+ AL N +
Sbjct: 1325 LEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKA---------ELQRALSKANTEVA 1375
Query: 3636 QDVESY--DPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLC 3693
Q Y D + E ++ + L + ++ T+ DL
Sbjct: 1376 QWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1435
Query: 3694 SRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQAL 3753
V N + + +++L + +E ++L Q E R L L +
Sbjct: 1436 LDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE----ARSLGTELFKIK 1491
Query: 3754 NEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQ 3800
N + + +T+ +NL++E +++T ++ E + E+E + +Q
Sbjct: 1492 NAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1538
Score = 45.1 bits (105), Expect = 0.002
Identities = 89/451 (19%), Positives = 179/451 (39%), Gaps = 48/451 (10%)
Query: 3087 NRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNS 3146
N V W + T+A+ + + +K L + +++ V K ++ + N
Sbjct: 1371 NTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNE 1430
Query: 3147 CVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMH---LNV 3203
+ + + NA A + R++ + + E +ELE Q L
Sbjct: 1431 VEDLMLDVERTNAACAALDKKQ-----RNFDKILAEWKQKCEETHAELEASQKEARSLGT 1485
Query: 3204 GLRKIK----ETVDQVEELRRDLRIKSQE---LEVKNAAANDKLKKMVKDQQEAEKKKVM 3256
L KIK E++DQ+E L+R+ + QE L + A ++ ++ K +++ E++K
Sbjct: 1486 ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCE 1545
Query: 3257 SQ----EIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMAN 3312
Q E + L ++ I Q+ + + +V+ + E + +K+ H+ V SM +
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605
Query: 3313 PPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYM 3372
A + L + D ++ + N +AE + +NY
Sbjct: 1606 TLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHAN------RMAAEAL---------RNYR 1650
Query: 3373 SNPSY--NYEIVNRASLACGPMVKWAIAQL-NYADMLK-RVEPLRNELQKLEDDAKDNQQ 3428
+ + +I +L +K +A + A++L+ +E LR L++ E K +Q
Sbjct: 1651 NTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQ 1710
Query: 3429 K---ANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAA----VEAKVNRSTALLKS 3481
+ A+E Q++ S+ K++ IS+ Q D+ E K ++
Sbjct: 1711 ELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAM 1770
Query: 3482 LSAERERWEKTS---ETFKNQMSTIAGDCLL 3509
++ E ++ + TS E K M D L
Sbjct: 1771 MAEELKKEQDTSAHLERMKKNMEQTVKDLQL 1801
Score = 33.5 bits (75), Expect = 5.1
Identities = 62/312 (19%), Positives = 123/312 (39%), Gaps = 20/312 (6%)
Query: 3207 KIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHK 3266
KIK + E + +K + ++K D+L K ++E E+K V + + L
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIK-----DELAKSEAKRKELEEKMVTLLKEKNDLQL 895
Query: 3267 QQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICL 3326
Q + A+ +E D++ I+ + +K + ++ E A A K LE C
Sbjct: 896 QVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAE-LTAKKRKLEDECS 954
Query: 3327 LLGESTTDWKQIRSIIMRENFIP--TIVNFSAE----EISDAIREKMKKNYMSNPSYNYE 3380
L + D + + + +E + N + E + + A K KK +
Sbjct: 955 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1014
Query: 3381 IVNRASLACGPMVKWAIAQLNYAD----MLKRVEPLRNELQ----KLEDDAKDNQQKANE 3432
+ + K I D L++ + LR +L+ KLE D K Q+ +
Sbjct: 1015 DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMD 1074
Query: 3433 VEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKT 3492
+E + L+ + + + E + L S+ + +A ++ K+ A ++ L E E +
Sbjct: 1075 IENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERAS 1134
Query: 3493 SETFKNQMSTIA 3504
+ Q S ++
Sbjct: 1135 RAKAEKQRSDLS 1146
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 53.9 bits (128), Expect = 4e-06
Identities = 114/647 (17%), Positives = 260/647 (40%), Gaps = 73/647 (11%)
Query: 3189 EKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQ- 3247
E+ + EE L RK+++ ++++ DL + ++E + A +K+K + ++
Sbjct: 930 ERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMA 989
Query: 3248 ------QEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKK 3301
+ K+K QE +Q + DK ++ + K+E V + + +++ KK
Sbjct: 990 GLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKK 1049
Query: 3302 QHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEE--- 3358
+ R+ +KLA ESI + E +Q+ + ++ F + + E+
Sbjct: 1050 LRMDLERAKRKLEGDLKLAQESIMDIENEK----QQLDEKLKKKEFEISNLQSKIEDEQA 1105
Query: 3359 ISDAIREKMKKNYMSNPSYNYEI-VNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQ 3417
+ +++K+K+ EI RAS A A+ +D+ + +E + L+
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASR--------AKAEKQRSDLSRELEEISERLE 1157
Query: 3418 K----LEDDAKDNQQKANEVEQMIRDL-------EASIARYKEEYAVLISE--------- 3457
+ + N+++ E ++M RDL EA+ A ++++A ++E
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQ 1217
Query: 3458 --AQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIA 3515
Q ++ + + ++ +++ + ++++S + EK T ++Q+S +
Sbjct: 1218 RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK----------- 1266
Query: 3516 YAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTE 3575
+ +QQ N T LQ + +F + E L + R + QA + ++L +
Sbjct: 1267 -SKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGK-QAFTQQIEELKRQ 1324
Query: 3576 NAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLV 3635
+K N + S + + +Y++ + ++ L+ AL N +
Sbjct: 1325 LEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKA---------ELQRALSKANTEVA 1375
Query: 3636 QDVESY--DPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLC 3693
Q Y D + E ++ + L + ++ T+ DL
Sbjct: 1376 QWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1435
Query: 3694 SRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQAL 3753
V N + + +++L + +E ++L Q E R L L +
Sbjct: 1436 LDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE----ARSLGTELFKIK 1491
Query: 3754 NEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQ 3800
N + + +T+ +NL++E +++T ++ E + E+E + +Q
Sbjct: 1492 NAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1538
Score = 45.1 bits (105), Expect = 0.002
Identities = 89/451 (19%), Positives = 179/451 (39%), Gaps = 48/451 (10%)
Query: 3087 NRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNS 3146
N V W + T+A+ + + +K L + +++ V K ++ + N
Sbjct: 1371 NTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNE 1430
Query: 3147 CVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMH---LNV 3203
+ + + NA A + R++ + + E +ELE Q L
Sbjct: 1431 VEDLMLDVERTNAACAALDKKQ-----RNFDKILAEWKQKCEETHAELEASQKEARSLGT 1485
Query: 3204 GLRKIK----ETVDQVEELRRDLRIKSQE---LEVKNAAANDKLKKMVKDQQEAEKKKVM 3256
L KIK E++DQ+E L+R+ + QE L + A ++ ++ K +++ E++K
Sbjct: 1486 ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCE 1545
Query: 3257 SQ----EIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMAN 3312
Q E + L ++ I Q+ + + +V+ + E + +K+ H+ V SM +
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605
Query: 3313 PPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYM 3372
A + L + D ++ + N +AE + +NY
Sbjct: 1606 TLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHAN------RMAAEAL---------RNYR 1650
Query: 3373 SNPSY--NYEIVNRASLACGPMVKWAIAQL-NYADMLK-RVEPLRNELQKLEDDAKDNQQ 3428
+ + +I +L +K +A + A++L+ +E LR L++ E K +Q
Sbjct: 1651 NTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQ 1710
Query: 3429 K---ANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAA----VEAKVNRSTALLKS 3481
+ A+E Q++ S+ K++ IS+ Q D+ E K ++
Sbjct: 1711 ELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAM 1770
Query: 3482 LSAERERWEKTS---ETFKNQMSTIAGDCLL 3509
++ E ++ + TS E K M D L
Sbjct: 1771 MAEELKKEQDTSAHLERMKKNMEQTVKDLQL 1801
Score = 33.5 bits (75), Expect = 5.1
Identities = 62/312 (19%), Positives = 123/312 (39%), Gaps = 20/312 (6%)
Query: 3207 KIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHK 3266
KIK + E + +K + ++K D+L K ++E E+K V + + L
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIK-----DELAKSEAKRKELEEKMVTLLKEKNDLQL 895
Query: 3267 QQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICL 3326
Q + A+ +E D++ I+ + +K + ++ E A A K LE C
Sbjct: 896 QVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAE-LTAKKRKLEDECS 954
Query: 3327 LLGESTTDWKQIRSIIMRENFIP--TIVNFSAE----EISDAIREKMKKNYMSNPSYNYE 3380
L + D + + + +E + N + E + + A K KK +
Sbjct: 955 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1014
Query: 3381 IVNRASLACGPMVKWAIAQLNYAD----MLKRVEPLRNELQ----KLEDDAKDNQQKANE 3432
+ + K I D L++ + LR +L+ KLE D K Q+ +
Sbjct: 1015 DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMD 1074
Query: 3433 VEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKT 3492
+E + L+ + + + E + L S+ + +A ++ K+ A ++ L E E +
Sbjct: 1075 IENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERAS 1134
Query: 3493 SETFKNQMSTIA 3504
+ Q S ++
Sbjct: 1135 RAKAEKQRSDLS 1146
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 53.5 bits (127), Expect = 5e-06
Identities = 67/349 (19%), Positives = 142/349 (40%), Gaps = 64/349 (18%)
Query: 3197 QQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVM 3256
+Q L+ + ++E + +EL + + QE++ K A D L + + +E E +
Sbjct: 1078 RQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEA---DFLAQEAQLLEELEASHIT 1134
Query: 3257 SQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAA 3316
Q+++ L Q+ A Q+ ++ ++E E Q ++ + L + S A
Sbjct: 1135 EQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYS------A 1188
Query: 3317 VKLALESICLLLGEST-------------TDWKQIRSIIMRENFIPTIVNFSAEEISDAI 3363
++ AL S+C E + D RS+ R P + SAE ++ A+
Sbjct: 1189 LQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRG---PLLTALSAEAVASAL 1245
Query: 3364 REKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDA 3423
K+ ++ W Q + LR+++QKLE+
Sbjct: 1246 H-KLHQDL-----------------------WKTQQTR--------DVLRDQVQKLEERL 1273
Query: 3424 KDNQQKANEVEQMIRDLEASIARYKEEYA-------VLISEAQAIKADLAAVEAKVNRST 3476
D + + ++V ++DL+ +++ +EE + L SE + +A++++++ R+
Sbjct: 1274 TDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAE 1333
Query: 3477 ALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMR 3525
ERE + E Q+ + + + A + AG ++ +R
Sbjct: 1334 LQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLR 1382
Score = 47.4 bits (111), Expect = 3e-04
Identities = 67/329 (20%), Positives = 141/329 (42%), Gaps = 44/329 (13%)
Query: 3188 HEK-----RSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKK 3242
HEK R + E+++ L K E++++ E++ ++R+K Q+ E++ A + ++
Sbjct: 851 HEKEVNQLREKWEKERSWHQQELAKALESLER-EKMELEMRLKEQQTEMEAIQAQREEER 909
Query: 3243 ------MVKDQQEAEKKKVMSQEI-----------QEQLHKQQEVIADKQMSVKEDLDKV 3285
+ + Q E EK++V E +QL + ++ + +++ +E +
Sbjct: 910 TQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGIL 969
Query: 3286 EPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRE 3345
+ + EAQ +K +QH ++ ++ E LL + KQ+ + +
Sbjct: 970 QTQLQEAQRELKEAARQHRDDLAALQ----------EESSSLLQDKMDLQKQVEDLKSQL 1019
Query: 3346 NFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVK-WAIAQLNYAD 3404
+E+ + +RE + N + +ASL M K + L AD
Sbjct: 1020 VAQDDSQRLVEQEVQEKLRETQEYNRIQKELER----EKASLTLSLMEKEQRLLVLQEAD 1075
Query: 3405 MLKRVE--PLRNELQKLEDDAKDNQQKANEVEQMIRDLEASI----ARYKEEYAVLISEA 3458
+++ E LR ++Q+ + + K+ + + Q +++ EA A+ EE
Sbjct: 1076 SIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITE 1135
Query: 3459 QAIKADLAAVEAKVNRSTALLKSLSAERE 3487
Q ++A L A EAK + L+S ++ E
Sbjct: 1136 QQLRASLWAQEAKAAQLQLRLRSTESQLE 1164
Score = 47.0 bits (110), Expect = 4e-04
Identities = 73/348 (20%), Positives = 150/348 (43%), Gaps = 43/348 (12%)
Query: 3177 LDFINHYANLFHEKRSELEEQQ----------MHLNVGLRKIKETVD-QVEELRRDLRIK 3225
+D ++ L + R EL +Q +NV L+ ++ Q EE + +L +
Sbjct: 458 VDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLA 517
Query: 3226 SQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKV 3285
+E E + L + Q E+ + + +E E H + E++ +Q V L +
Sbjct: 518 VRERE----RLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARA 573
Query: 3286 EPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRE 3345
E ++ E ++ ++K + + ++R+ AAVKL+ + L L + + + ++ + E
Sbjct: 574 EQSIAELSSSENTLKTE-VADLRA-----AAVKLSALNEALALDKVGLNQQLLQ--LEEE 625
Query: 3346 NFIPTIVNFSAEEISDAIR------EKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQ 3399
N +AE+ +A++ EK ++ ++ + +A A +
Sbjct: 626 NQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAEL------- 678
Query: 3400 LNYADMLKRVEPLRNELQKLEDDAKDNQQKAN----EVEQMIRDLEASIARYKEEYAVLI 3455
AD L+ ++ + E+QK +++ Q+ A ++ Q + E +AR +E L+
Sbjct: 679 --QAD-LRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALV 735
Query: 3456 SEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTI 3503
E A++ L AVE L+ LS+ +E E + + Q S I
Sbjct: 736 REKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVI 783
Score = 41.2 bits (95), Expect = 0.024
Identities = 57/324 (17%), Positives = 130/324 (40%), Gaps = 53/324 (16%)
Query: 3180 INHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDK 3239
+ H + +K E+E QQ H++ +++E DQ+E+ + L K E + + +
Sbjct: 1724 LEHMKLILRDKEKEVECQQEHIH----ELQELKDQLEQQLQGLHRKVGETSLLLSQREQE 1779
Query: 3240 LKKMVKDQQEA-EKKKVMSQEIQEQLHKQQEVIADKQMS-----------------VKED 3281
+ + + QEA E+ ++ Q +Q QL + Q +A + VKE
Sbjct: 1780 IVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEK 1839
Query: 3282 LDKVEPAVIEAQNAVKSIK---KQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQI 3338
D ++ A+ +A +K + H + R + A ++++ +LG+ + ++
Sbjct: 1840 ADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESRE- 1898
Query: 3339 RSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIA 3398
+E + + AE+ + +E+ RA W A
Sbjct: 1899 -----QEKALLALQQQCAEQAQE-----------------HEVETRAL-----QDSWLQA 1931
Query: 3399 QLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEA 3458
Q + + +E LR E Q + + +A +++ + A++ ++ +
Sbjct: 1932 QAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELS 1991
Query: 3459 QAIKADLAAVEAKVNRSTALLKSL 3482
++++A A ++A ++ A + L
Sbjct: 1992 RSLEASTATLQASLDACQAHSRQL 2015
Score = 40.8 bits (94), Expect = 0.032
Identities = 60/332 (18%), Positives = 148/332 (44%), Gaps = 37/332 (11%)
Query: 3189 EKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVK-------NAAANDKLK 3241
++R L E+ HL L+K +E +++ RD++ + +E++ K AA +L+
Sbjct: 652 KRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLE 711
Query: 3242 KMVKDQQEAEKKKVMSQEIQEQ----------------LHKQQEVIADKQMSVKEDLDKV 3285
++ Q+ +++V+++ +QE+ + + ++ +A++ + + +
Sbjct: 712 QL--HQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELL 769
Query: 3286 EPAVIEA--QNAVKSIKKQHL-VEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSII 3342
E ++ EA QN+V + K L V+++++ ++ + + L L + +Q R
Sbjct: 770 ESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAA 829
Query: 3343 MRENFIPTIVNFSAEEISDAIREK----MKKNYMSNPSYNYEIVNRA--SLACGPMVKWA 3396
R+ +A E A EK +++ + S++ + + +A SL M
Sbjct: 830 ARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEM 889
Query: 3397 IAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLIS 3456
+ +M + ++ R E + + A Q E E++ L ++ + ++E A
Sbjct: 890 RLKEQQTEM-EAIQAQREEERTQAESALCQMQLETEKERV--SLLETLLQTQKELADASQ 946
Query: 3457 EAQAIKADLAAVEAKVNRSTALLKSLSAERER 3488
+ + ++ D+ + K +T +L++ E +R
Sbjct: 947 QLERLRQDMKVQKLKEQETTGILQTQLQEAQR 978
Score = 40.8 bits (94), Expect = 0.032
Identities = 77/399 (19%), Positives = 179/399 (44%), Gaps = 64/399 (16%)
Query: 3189 EKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRI-----KSQELEVKNAAANDKLK-- 3241
++ S +E + L V ++ + + + ++ R L++ +SQ + ++AAA +
Sbjct: 778 QQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE 837
Query: 3242 ---KMVKDQQEAEKKKVMSQEIQEQLHKQ----QEVIADKQMSVKEDLDKVEPAVIEAQN 3294
K +QQ+A +K ++Q ++E+ K+ Q+ +A S++ + ++E + E Q
Sbjct: 838 QEGKTALEQQKAAHEKEVNQ-LREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQT 896
Query: 3295 AVKSIKKQHLVEVRSMANPPAAVKLALES--ICLL---------LGESTTDWKQIRSII- 3342
+++I+ Q E + ++L E + LL L +++ +++R +
Sbjct: 897 EMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMK 956
Query: 3343 ---MRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQ 3399
++E I+ +E ++E +++ R LA ++ Q
Sbjct: 957 VQKLKEQETTGILQTQLQEAQRELKEAARQH-------------RDDLAALQEESSSLLQ 1003
Query: 3400 LNYADMLKRVEPLRNEL-------QKLEDDAKDNQQKANEVEQMIRDLEASIARY----- 3447
+ D+ K+VE L+++L + +E + ++ ++ E ++ ++LE A
Sbjct: 1004 -DKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLM 1062
Query: 3448 -KEEYAVLISEAQAIKA-DLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAG 3505
KE+ +++ EA +I+ +L+A+ + + K LSA+ E + E + + +A
Sbjct: 1063 EKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQ--EVKEKEADFLAQ 1120
Query: 3506 DCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFR 3544
+ L A + +QQ+R +L W+ + A +Q R
Sbjct: 1121 EAQLLEELEA-SHITEQQLRASL---WAQEAKAAQLQLR 1155
Score = 37.4 bits (85), Expect = 0.35
Identities = 59/304 (19%), Positives = 131/304 (43%), Gaps = 34/304 (11%)
Query: 3257 SQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAA 3316
S++++E L Q+ I D+ + +ED+ +++ A+ + ++ +++ + +S+A
Sbjct: 2012 SRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQ---R 2068
Query: 3317 VKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPS 3376
V+ + LG+ + ++IR + + + +EI + +RE ++N +
Sbjct: 2069 VQENMIQEKQNLGQEREE-EEIRGLHQSVRELQLTLAQKEQEILE-LRETQQRNNLEALP 2126
Query: 3377 YNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEP-LRNELQKLEDDAKDNQQKANEVEQ 3435
++++ PM + ++ L +EP L+ EL++L+ + + + E +
Sbjct: 2127 HSHKT--------SPMEEQSLK-------LDSLEPRLQRELERLQAALRQTEAREIEWRE 2171
Query: 3436 MIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNR--STALLKSLSAERERWEKTS 3493
+DL S+A+ K + L A ++A + +++ R L + E+ER
Sbjct: 2172 KAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPG 2231
Query: 3494 ET------FKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDI 3547
T + + G+ A + G Q RQ L HLQQA + D
Sbjct: 2232 ATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRL-----EHLQQAVARLEIDR 2286
Query: 3548 ARTE 3551
+R +
Sbjct: 2287 SRLQ 2290
Score = 37.0 bits (84), Expect = 0.46
Identities = 59/324 (18%), Positives = 132/324 (40%), Gaps = 50/324 (15%)
Query: 3193 ELEEQQMHLNVGLRKIKETVDQVE-------ELRRDLRIKSQELEVKNAAAND---KLKK 3242
ELEE + + IKE Q E L DL +SQEL+ +++ +D
Sbjct: 1561 ELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTV 1620
Query: 3243 MVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQ 3302
+ ++ QE +++ +E E+L +Q+E + +DL++ + ++ + ++ ++ Q
Sbjct: 1621 LARELQERDQEVKSQREQIEELQRQKE-------HLTQDLERRDQELMLQKERIQVLEDQ 1673
Query: 3303 HLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPT-IVNFSAEEISD 3361
+ + + +KL+L G T +Q+ E P+ S E +
Sbjct: 1674 RTRQTKILEEDLEQIKLSLRE----RGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKL 1729
Query: 3362 AIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLED 3421
+R+K K+ + C Q + ++ + + L +LQ L
Sbjct: 1730 ILRDKEKE-----------------VEC--------QQEHIHELQELKDQLEQQLQGLHR 1764
Query: 3422 DAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKS 3481
+ ++ EQ I L+ + +E+ + + Q++++ L + + + L++
Sbjct: 1765 KVGETSLLLSQREQEIVVLQQQLQEAREQGEL---KEQSLQSQLDEAQRALAQRDQELEA 1821
Query: 3482 LSAERERWEKTSETFKNQMSTIAG 3505
L E+++ + E K + + G
Sbjct: 1822 LQQEQQQAQGQEERVKEKADALQG 1845
Score = 36.6 bits (83), Expect = 0.60
Identities = 53/307 (17%), Positives = 123/307 (40%), Gaps = 8/307 (2%)
Query: 3193 ELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEK 3252
+L +Q + +++ DQ EE + LR + Q+L + + + + K
Sbjct: 404 DLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSK 463
Query: 3253 KKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMAN 3312
++ + Q+ +E+L +Q EV+ + ++ +V + ++ + K++ E+
Sbjct: 464 ERELLQKAREELRQQLEVLEQEAWRLR----RVNVELQLQGDSAQGQKEEQQEELHLAVR 519
Query: 3313 PPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYM 3372
++ L + ES ++ +R + + ++ E++ A+ +
Sbjct: 520 ERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAE 579
Query: 3373 SNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANE 3432
+ S N A L + ++ LN A L +V L +L +LE++ + +
Sbjct: 580 LSSSENTLKTEVADLRAAAV---KLSALNEALALDKV-GLNQQLLQLEEENQSVCSRMEA 635
Query: 3433 VEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKT 3492
EQ L+ +A ++ L + ++A L E A L+ + E+E +K
Sbjct: 636 AEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKK 695
Query: 3493 SETFKNQ 3499
++Q
Sbjct: 696 LSESRHQ 702
Score = 34.7 bits (78), Expect = 2.3
Identities = 49/282 (17%), Positives = 113/282 (40%), Gaps = 48/282 (17%)
Query: 3222 LRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKED 3281
L K+QELE + A+++ +++++ + + + +K E+Q+++ + ++ Q ED
Sbjct: 249 LLAKTQELEKE---AHERSQELIQLKSQGDLEKA---ELQDRVTELSALLTQSQKQ-NED 301
Query: 3282 LDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSI 3341
+K+ A+ E +++ + + S++ KL+L+ + K I +
Sbjct: 302 YEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVI----------KDITQV 351
Query: 3342 IMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLN 3401
++ E I S E S + + +Q +
Sbjct: 352 MVEEG--DNIAQGSGHENSLELDSSI-----------------------------FSQFD 380
Query: 3402 YADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAI 3461
Y D K + +R+ L + +D +Q+ ++ + L+ +++EE L Q +
Sbjct: 381 YQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKL 440
Query: 3462 KADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTI 3503
+ + + + SLS ERE +K E + Q+ +
Sbjct: 441 TGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVL 482
Score = 33.9 bits (76), Expect = 3.9
Identities = 20/94 (21%), Positives = 39/94 (41%)
Query: 3186 LFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVK 3245
L + L Q HL + + + L DLR L++KN + ++
Sbjct: 1345 LLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQA 1404
Query: 3246 DQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVK 3279
Q++ E K + +QE L + +A+++ V+
Sbjct: 1405 LQEQGELKVAQGKALQENLALLTQTLAEREEEVE 1438
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 53.5 bits (127), Expect = 5e-06
Identities = 72/344 (20%), Positives = 150/344 (43%), Gaps = 41/344 (11%)
Query: 3177 LDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETV-------DQVEELRRDLRIKSQEL 3229
++ + +L +++ EL+ + LN IK T ++ +LR +L K QEL
Sbjct: 424 IEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQEL 483
Query: 3230 EVKNAAANDK------LKKMVKDQQEAEKKKVMSQEIQEQLHKQQ----EVIADKQMSVK 3279
N + ++K ++++ + QEA K ++ I++QL KQQ +I+ + +
Sbjct: 484 ---NQSISEKETLIAEIEELDRQNQEATKHMIL---IKDQLSKQQNEGDSIISKLKQDLN 537
Query: 3280 EDLDKVEPAVIEAQNAVK--SIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQ 3337
++ +V + + K ++K+ L++ N K LE L + ++
Sbjct: 538 DEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQE 597
Query: 3338 IRSIIMRENF-IPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWA 3396
I +EN + + + EE+S IR ++ ++ + + N++ ++K
Sbjct: 598 SNVSIQKENLELKEHIRQNEEELS-RIRNELMQSLNQDSNSNFK---------DTLLKER 647
Query: 3397 IAQL-NYADMLKRVEPLRNELQKLEDDAK-DNQQKANEVEQMIRDLEASIARYKEEYAVL 3454
A++ N L +E L L+K+ D K +N++ E + LE +A +
Sbjct: 648 EAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEK 707
Query: 3455 ISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKN 3498
+ + +K + +EA++ + K L E ++EKT E N
Sbjct: 708 NTIVETLKMEKGEIEAELCWAK---KRLLEEANKYEKTIEELSN 748
Score = 38.5 bits (88), Expect = 0.16
Identities = 63/321 (19%), Positives = 132/321 (41%), Gaps = 42/321 (13%)
Query: 3193 ELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEK 3252
+LE+ +M + L KE + Q E DL + Q+LE K D+L K + +K
Sbjct: 545 QLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQK 604
Query: 3253 KKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMAN 3312
+ + E++E + + +E ++ + + + L++ + N ++ K+ EVR+
Sbjct: 605 ENL---ELKEHIRQNEEELSRIRNELMQSLNQDSNS-----NFKDTLLKEREAEVRN--- 653
Query: 3313 PPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYM 3372
L ++ ++ +Q+ + + F + N + +R ++++
Sbjct: 654 ---------------LKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLA 698
Query: 3373 SNPSYNYE---IVNRASLACGPM---VKWAIAQL-----NYADMLKRVEPLRN---ELQK 3418
N + E IV + G + + WA +L Y ++ + RN +
Sbjct: 699 GNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQ 758
Query: 3419 LEDD--AKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRST 3476
LE + K NQ+K E+ ++ +++E +KE VL S + K + K
Sbjct: 759 LEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIE 818
Query: 3477 ALLKSLSAERERWEKTSETFK 3497
L + S +E +K S+ +
Sbjct: 819 KLKERSSKLQEELDKYSQALR 839
Score = 36.2 bits (82), Expect = 0.78
Identities = 32/136 (23%), Positives = 63/136 (46%), Gaps = 17/136 (12%)
Query: 3181 NHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKL 3240
N N H+ ++E Q LNV ++ ET L++ + +VK A +
Sbjct: 1625 NAMENASHQASVQVESLQEQLNVVSKQRDETA---------LQLSVSQEQVKQYALSLAN 1675
Query: 3241 KKMVKDQQEAEKKKVMSQEIQEQLH------KQQEVIADKQMSVKEDLDKVEPAVIEAQN 3294
+MV + + E+K + S E+++Q K E + K +S++E LD+ A+ A
Sbjct: 1676 LQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASR 1735
Query: 3295 AVK--SIKKQHLVEVR 3308
+ +K++ + E++
Sbjct: 1736 LTEQLDVKEEQIEELK 1751
Score = 35.8 bits (81), Expect = 1.0
Identities = 25/113 (22%), Positives = 57/113 (50%), Gaps = 5/113 (4%)
Query: 3187 FHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRD---LRIKSQELEVKNAAANDKLKKM 3243
+ E+ ELE G+ I+ + ++ E+++ L+I+ E K DK+K +
Sbjct: 261 YEERIEELENLLQQGGSGV--IETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDI 318
Query: 3244 VKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAV 3296
K AE + + + QEQL+ ++ I ++ ++K + K++P+ ++ + +
Sbjct: 319 NKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTM 371
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 53.5 bits (127), Expect = 5e-06
Identities = 64/339 (18%), Positives = 143/339 (42%), Gaps = 27/339 (7%)
Query: 3187 FHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKD 3246
+ EK EL+++ L + ++++ + +R + QEL K + K+ K
Sbjct: 1604 WQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQ 1663
Query: 3247 QQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVE 3306
QEAE++ +E++E++ K + K + ++E+ D++ V A + K + L
Sbjct: 1664 LQEAEQE---MEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSS 1720
Query: 3307 VRSMANPPAAVKLALESIC----LLLGESTTDWKQIRSIIMR-ENFIPTIVNFSAEEISD 3361
SM VK+ E++ L+ E + ++++ + + E + N A E D
Sbjct: 1721 NASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1780
Query: 3362 AIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYA---------------DML 3406
++ S P E + S++ P ++ A + L
Sbjct: 1781 NQTNVTEEGTQSIPGETEE-QDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYL 1839
Query: 3407 KRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLA 3466
++++ L+ + LE++ + N++ + +E L + I+ E +L E +
Sbjct: 1840 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQ 1899
Query: 3467 AVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAG 3505
++ +++R T L ++ E++ E E NQ++ + G
Sbjct: 1900 QIQEELSRVTKLKETAEEEKDDLE---ERLMNQLAELNG 1935
Score = 41.6 bits (96), Expect = 0.019
Identities = 112/663 (16%), Positives = 274/663 (41%), Gaps = 64/663 (9%)
Query: 3177 LDFINHYANLFHEK-RSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAA 3235
L ++H A + E + +LE Q+ + GL ++E +++EL++ + K +++ +
Sbjct: 1356 LKTVSHEAEVHAESLQQKLESSQLQI-AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQ 1414
Query: 3236 ANDKLKKMVKDQQEAEKK----KVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIE 3291
++K + K Q E ++ K + +++ Q + E I Q+ + E K E + E
Sbjct: 1415 LSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPE-EIGE 1473
Query: 3292 AQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLG---ESTTDWKQIRSIIMREN-F 3347
A + I+++ + S K E + L G T + S + +N
Sbjct: 1474 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1533
Query: 3348 IPTIVNFSA--EEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQL--NYA 3403
T++ A +E D + +M ++ + N S S +C +K A+ L +
Sbjct: 1534 KDTVLGRLALLQEERDKLITEMDRSLLENQS--------LSSSC-ESLKLALEGLTEDKE 1584
Query: 3404 DMLKRVEPLRN----ELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQ 3459
++K +E L++ E + ++ K+ Q++ + Q ++ R + + E Q
Sbjct: 1585 KLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQ 1644
Query: 3460 AIKADLAAVEAKVNRSTALLKSLSAE----RERWEKTSETFKNQMSTIAGDCLLSAAFIA 3515
+ L + EA + L+ E +E+ K +++ + ++ + + A +
Sbjct: 1645 ELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVH 1704
Query: 3516 YAGYFDQQMRQNLFT---TWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPAD-D 3571
AG ++ + L + + L++ +++ T + + L + + L + L +
Sbjct: 1705 PAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIE 1764
Query: 3572 LCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGN 3631
L+ ++ + + + T+ I E +++ S +++ SA + N
Sbjct: 1765 GNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMS-TRPTCSESVPSA-KSAN 1822
Query: 3632 PLLVQDVESYDPVLNPVLN-----------REVRRTGGRVLITLGDQDIDLSPSFVIFLS 3680
P + +D S+D + N + E ++ TL ++ L +S
Sbjct: 1823 PAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQ----IS 1878
Query: 3681 TRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQL 3740
T+D ++ + +++ +N + + L E + E+ D++E+ +
Sbjct: 1879 TKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMN---------- 1928
Query: 3741 RLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVET-VSQ 3799
+L +L S+ +V + ++ + + ++NLK+ +E+ + ++ +VE+ + +
Sbjct: 1929 QLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1988
Query: 3800 QYL 3802
+YL
Sbjct: 1989 EYL 1991
Score = 41.2 bits (95), Expect = 0.024
Identities = 38/141 (26%), Positives = 64/141 (45%), Gaps = 12/141 (8%)
Query: 1242 KIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGR------LKDDRE 1295
K+ E ++++ + TDL EK K GNL Q I KF L+ RE
Sbjct: 2309 KLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2368
Query: 1296 KCAKAKEALELTDT---GLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWV 1352
++ E + + + LLSG EE +QVA+ EL+ E+ ++ + Q +E+ V
Sbjct: 2369 LTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHD--KEIKELENLLSQEEEENIV 2426
Query: 1353 -SVQPRKLRQNLDALLNQLKS 1372
+ +K + L+ LK+
Sbjct: 2427 LEEENKKAVDKTNQLMETLKT 2447
Score = 40.8 bits (94), Expect = 0.032
Identities = 106/530 (20%), Positives = 213/530 (40%), Gaps = 77/530 (14%)
Query: 1223 DIMRRKDSAIQQQVANLQMKIVQEDRAV-------ESRTTDLLTDWEKTKPVTGNLRPEE 1275
DI+R+KD +QQ+ LQ + D + +++ T L E+ K G + P E
Sbjct: 66 DIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTE 125
Query: 1276 ALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSE 1335
+ + +++ E K K L+ + + + + Q E+ E
Sbjct: 126 PQSEEQLSKHDKSSTEEEME-IEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEE 184
Query: 1336 LSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMK 1395
+ +Q+ + +E ++S +L Q Q + ++ + F ++ +
Sbjct: 185 FVMMKQQLQEKEE--FISTLQAQLSQ------TQAEQAAQQVVREKDARFETQVRLHEDE 236
Query: 1396 INMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQKNEAIVKDVLLVAQG 1455
+ LV + E + + L ++L + E +G+ VDL + E + Q
Sbjct: 237 LLQLVTQADVETEMQQKLRVLQRKLEEH---EESLVGRAQVVDLLQQELTAAE-----QR 288
Query: 1456 EMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKV 1515
L + L+Q+ NT + + + +++ +L V+ KLS ++ +
Sbjct: 289 NQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMEL---------EVAERKLS-FHNL 338
Query: 1516 FEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIK--HLLPVETQRFQSIST 1573
EE L + +++ R+ LE + K H+L ++ + Q + +
Sbjct: 339 QEE----MHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQ-KTGQELQS 393
Query: 1574 EFLALMKKVSKSPLVMDVLNIQGVQ--RSLERLADLLGKIQKALGEYLER---------E 1622
AL + SK ++ N Q VQ +++++L D L + K + ++L R
Sbjct: 394 ACDALKDQNSK---LLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETAS 450
Query: 1623 RSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGE 1682
++SFP Y G + + E +N+A LQK ++ E+ L +SS E E
Sbjct: 451 QTSFPDVYNEGTQAVTE-----ENIASLQKR----------VVELENEKGALLLSSIELE 495
Query: 1683 EVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATS 1732
E+ E+ K++ +TL+E + R A ++ V+I K +S
Sbjct: 496 ELK-------AENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSS 538
Score = 37.4 bits (85), Expect = 0.35
Identities = 64/335 (19%), Positives = 140/335 (41%), Gaps = 20/335 (5%)
Query: 3184 ANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKM 3243
+ L +S+L+ ++ + G +++ +VEEL + L K E+ + +K + +
Sbjct: 830 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDV 889
Query: 3244 VKDQQEAEKKKVMSQEI-------QEQLHKQQEVIADKQMSVKEDL------DKVEPAVI 3290
QQ E+K EI QL++++ + + ++KE L ++ + +
Sbjct: 890 ETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQV 949
Query: 3291 EAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPT 3350
E N V S KQ+ E+ S A + +L E LL E+ +++++ ++ +
Sbjct: 950 EEDNEVSSGLKQNYDEM-SPAGQISKEELQHE-FDLLKKENEQRKRKLQAALINRKELLQ 1007
Query: 3351 IVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVE 3410
V+ EE+++ E K+ +S ++ + + Q + + +
Sbjct: 1008 RVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTIS 1067
Query: 3411 PLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVL---ISEAQAI--KADL 3465
ELQ + D ++ + + +++ + ++ + +L ISE QAI K
Sbjct: 1068 EKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLIT 1127
Query: 3466 AAVEAKVNRSTALLKSLSAERERWEKTSETFKNQM 3500
+ +A S AL+K +SE +K ++
Sbjct: 1128 SNTDASDGDSVALVKETVVISPPCTGSSEHWKPEL 1162
Score = 33.1 bits (74), Expect = 6.6
Identities = 60/328 (18%), Positives = 143/328 (43%), Gaps = 45/328 (13%)
Query: 3196 EQQMHLNVGLRKIKETVDQVEELRRDLRIKSQEL---EVKNAAANDKLKKMVKD------ 3246
E Q L V RK++E + + + + + QEL E +N + +L++M +
Sbjct: 249 EMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRN 308
Query: 3247 --QQEAEKKKVMSQEIQEQLHKQQ---EVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKK 3301
+ E E+ K++ ++++ ++ +++ + ++ + E ++ A E ++ ++++
Sbjct: 309 TVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQ 368
Query: 3302 QHLVEVRSMANPPAAVKLA---LESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEE 3358
+H E+ + +++ L+S C L + + Q ++ E + + ++
Sbjct: 369 KHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKN----EQAVQSAQTI--QQ 422
Query: 3359 ISDAIREKMKK--NYMSN-PSYNYEIVNRASLACGPMV----KWAIAQLNYADMLKRVEP 3411
+ D +++K K+ +++ P +E ++ S P V A+ + N A + KRV
Sbjct: 423 LEDQLQQKSKEISQFLNRLPLQQHETASQTSF---PDVYNEGTQAVTEENIASLQKRVVE 479
Query: 3412 LRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAK 3471
L NE L + +E + +L+A + + +L ++ + +AD E
Sbjct: 480 LENEKGAL---------LLSSIE--LEELKAENEKLSSQITLLEAQNRTGEADREVSEIS 528
Query: 3472 VNRSTALLKSLSAERERWEKTSETFKNQ 3499
+ A +S SAE + TF +
Sbjct: 529 I-VDIANKRSSSAEESGQDVLENTFSQK 555
>gi|75677376 coiled-coil domain containing 62 isoform b [Homo sapiens]
Length = 684
Score = 52.0 bits (123), Expect = 1e-05
Identities = 60/281 (21%), Positives = 132/281 (46%), Gaps = 25/281 (8%)
Query: 3212 VDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQ----EAEKKKVMSQE-----IQE 3262
+ +E+ R++L++ EL+ ++ ND + V QQ E +++KV++ E ++
Sbjct: 20 ISTIEKQRKELQLLIGELKDRDKELNDMVA--VHQQQLLSWEEDRQKVLTLEERCSKLEG 77
Query: 3263 QLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALE 3322
+LHK+ E+I VK +E +E Q A++ + Q L E+ A + + LE
Sbjct: 78 ELHKRTEIIRSLTKKVK----ALESNQMECQTALQKTQLQ-LQEMAQKATHSSLLSEDLE 132
Query: 3323 SICLLLGESTTDWK-QIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEI 3381
+ L + + Q+ + RE + T++ ++I +A+ N++++ S +++
Sbjct: 133 ARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAV------NHIADCSGKFKM 186
Query: 3382 VNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLE 3441
+ A L M + I + D ++++ L+ E+ KL++D + + NE + I L+
Sbjct: 187 LEHA-LRDAKMAETCIVK-EKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLK 244
Query: 3442 ASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSL 3482
+ +E + + L ++K R+ + L +L
Sbjct: 245 QEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNL 285
>gi|30348972 coiled-coil domain containing 62 isoform a [Homo sapiens]
Length = 682
Score = 52.0 bits (123), Expect = 1e-05
Identities = 60/281 (21%), Positives = 132/281 (46%), Gaps = 25/281 (8%)
Query: 3212 VDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQ----EAEKKKVMSQE-----IQE 3262
+ +E+ R++L++ EL+ ++ ND + V QQ E +++KV++ E ++
Sbjct: 20 ISTIEKQRKELQLLIGELKDRDKELNDMVA--VHQQQLLSWEEDRQKVLTLEERCSKLEG 77
Query: 3263 QLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALE 3322
+LHK+ E+I VK +E +E Q A++ + Q L E+ A + + LE
Sbjct: 78 ELHKRTEIIRSLTKKVK----ALESNQMECQTALQKTQLQ-LQEMAQKATHSSLLSEDLE 132
Query: 3323 SICLLLGESTTDWK-QIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEI 3381
+ L + + Q+ + RE + T++ ++I +A+ N++++ S +++
Sbjct: 133 ARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAV------NHIADCSGKFKM 186
Query: 3382 VNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLE 3441
+ A L M + I + D ++++ L+ E+ KL++D + + NE + I L+
Sbjct: 187 LEHA-LRDAKMAETCIVK-EKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLK 244
Query: 3442 ASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSL 3482
+ +E + + L ++K R+ + L +L
Sbjct: 245 QEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNL 285
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 50.8 bits (120), Expect = 3e-05
Identities = 75/339 (22%), Positives = 146/339 (43%), Gaps = 42/339 (12%)
Query: 3192 SELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEV--KNAAANDKLKKMVKDQQE 3249
+++++ + L ++ E ++Q + + +L Q LE K A K+ + VK + E
Sbjct: 1192 AQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESE 1251
Query: 3250 AEKKKVMSQEIQEQLHKQQE------VIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQH 3303
++KK+ +Q +QE K E +A+K ++ +LD V + EA+ K IK
Sbjct: 1252 HKRKKLDAQ-VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEK--KGIK--- 1305
Query: 3304 LVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAI 3363
A A+++ L+ LL E T + S I + + EE +A
Sbjct: 1306 ------FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEA- 1358
Query: 3364 REKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQ------ 3417
R+ ++K ++ S + + G + A+ +LK E L L+
Sbjct: 1359 RKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAK---KKLLKDAEALSQRLEEKALAY 1415
Query: 3418 -KLEDDAKDNQQKANEVEQMI---RDLEASIARYKEEYAVLISEAQAIKA------DLAA 3467
KLE QQ+ +++ + R + +++ + ++++ L++E ++I A D A
Sbjct: 1416 DKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAE 1475
Query: 3468 VEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGD 3506
EA+ + AL SL+ E + E F+ Q + D
Sbjct: 1476 AEAREKETKAL--SLARALEEALEAKEEFERQNKQLRAD 1512
Score = 43.9 bits (102), Expect = 0.004
Identities = 62/331 (18%), Positives = 146/331 (44%), Gaps = 26/331 (7%)
Query: 3190 KRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQE 3249
K +L E++ L L+ E + EE+R L K QELE L+ V++++E
Sbjct: 881 KHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELE----EILHDLESRVEEEEE 936
Query: 3250 A------EKKKVMS--QEIQEQLHKQQ---EVIADKQMSVKEDLDKVEPAV--IEAQNAV 3296
EKKK+ + Q+++EQL +++ + + ++++ + + K+E + +E QN+
Sbjct: 937 RNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNS- 995
Query: 3297 KSIKKQHLVE--VRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNF 3354
K IK++ L+E + ++ A + +++ + + + + +E +
Sbjct: 996 KFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEK 1055
Query: 3355 SAEEI---SDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEP 3411
+ ++ + +++++ + ++ + G + + L+ + LK V
Sbjct: 1056 AKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRE 1115
Query: 3412 LRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAK 3471
L+ ++ +L++D + + N+ E+ RDL + K E + A + E +
Sbjct: 1116 LQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQE 1175
Query: 3472 VNRSTALLKSLSAERERWEKTSETFKNQMST 3502
V L K+L E + E + + + +T
Sbjct: 1176 V---AELKKALEEETKNHEAQIQDMRQRHAT 1203
Score = 43.1 bits (100), Expect = 0.006
Identities = 63/349 (18%), Positives = 144/349 (41%), Gaps = 39/349 (11%)
Query: 3189 EKRSELEEQQMHLNVGLRKIKETVDQVEELRRD----------LRIKSQELEVKNAAAND 3238
+ R E E++ L + ++++E ++E+ R+ + I ++LE + AAN
Sbjct: 1581 QTRDEQNEEKKRLLI--KQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANK 1638
Query: 3239 KLKKMVKDQQEAE-KKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVK 3297
+++K ++ + + K +E++E + E+ A + S K+ L +E +++ Q +
Sbjct: 1639 ARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKK-LKSLEAEILQLQEELA 1697
Query: 3298 SIKK----------QHLVEVRSMANPPAAV---KLALESICLLLGESTTDWKQIRSIIMR 3344
S ++ + E+ + A+ +A+ K LE+ L E + +Q ++
Sbjct: 1698 SSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEE-EQSNMELLN 1756
Query: 3345 ENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYAD 3404
+ F T + ++ E+ N E N+ A ++ A+ A
Sbjct: 1757 DRFRKTTLQVDTLN-AELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKAT 1815
Query: 3405 MLKRVEPLRNELQKLEDDAKD----------NQQKANEVEQMIRDLEASIARYKEEYAVL 3454
+ + ++LE +AK+ ++K E+ + D +YKE+
Sbjct: 1816 ISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKA 1875
Query: 3455 ISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTI 3503
+ + +K L E + R+ A + L E + + +E ++ST+
Sbjct: 1876 NARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTL 1924
Score = 42.0 bits (97), Expect = 0.014
Identities = 71/360 (19%), Positives = 146/360 (40%), Gaps = 45/360 (12%)
Query: 3178 DFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAAN 3237
D + + + + LE+Q + L ++++ + E+ + L + Q ++ A
Sbjct: 1521 DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK-----AQ 1575
Query: 3238 DKLKKMVKDQQEAEKKKVMSQEIQ------EQLHKQQEVIADKQMSVKEDLDKVEPAVIE 3291
+ +D+Q EKK+++ ++++ E KQ+ + + ++ DL +E A IE
Sbjct: 1576 FERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLE-AQIE 1634
Query: 3292 AQN-----AVKSIKK---------QHLVEVRSMANPPAAVK-------LALESICLLLGE 3330
A N +K ++K + L E R+ + A +LE+ L L E
Sbjct: 1635 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Query: 3331 STTDWKQIRSIIMRE-NFIPTIVNFSAEEISDAIREKMK--------KNYMSNPSYNYEI 3381
++ R +E + + + SA S + EK + + + N E+
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
Query: 3382 VNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRD-L 3440
+N V A+L A + N Q+LE K+ + K E+E ++
Sbjct: 1755 LNDRFRKTTLQVDTLNAEL--AAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKF 1812
Query: 3441 EASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQM 3500
+A+I+ + + L + + + AA V R+ LK + + E + ++ +K QM
Sbjct: 1813 KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM 1872
Score = 40.0 bits (92), Expect = 0.054
Identities = 123/646 (19%), Positives = 257/646 (39%), Gaps = 122/646 (18%)
Query: 3195 EEQQMHLNVGLRKIKETVDQVE-ELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKK 3253
EE+ + L K+KE +VE EL R Q LE KN A ++L+ + EAE+
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILA-EQLQAETELFAEAEEM 909
Query: 3254 KVM----SQEIQEQLH----------KQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSI 3299
+ QE++E LH ++ +++ +++ ++ + +E + E + A + +
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL 969
Query: 3300 KKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEI 3359
+ + + A +K E I LL +++ K I+ + E+ I + AEE
Sbjct: 970 QLEKVTA-------EAKIKKMEEEILLLEDQNS---KFIKEKKLMEDRIAECSSQLAEE- 1018
Query: 3360 SDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQK- 3418
E+ KN +I N+ + + + LK+ E R EL+K
Sbjct: 1019 -----EEKAKNLA-------KIRNKQEVMISDL----------EERLKKEEKTRQELEKA 1056
Query: 3419 ---LEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEA--------QAIKADLAA 3467
L+ + D Q + E++ I +L+ +A+ +EE ++ A+K +
Sbjct: 1057 KRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKV-VRE 1115
Query: 3468 VEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQN 3527
++A++ +S A R + EK ++ + ++
Sbjct: 1116 LQAQIAELQEDFESEKASRNKAEKQKRDLSEELEAL-----------------KTELEDT 1158
Query: 3528 LFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYP 3587
L TT Q ++ + + E +E + + + D+ +A L+ +
Sbjct: 1159 LDTT----AAQQELRTKREQEVAELKKALEEETKNHEAQI--QDMRQRHATALEELS--- 1209
Query: 3588 LIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNP 3647
+ QA F N K+++ T K L ++ ++Q V++
Sbjct: 1210 ---EQLEQAKRFKANLEKNKQGLETD------NKELACEVK-----VLQQVKAESEHKRK 1255
Query: 3648 VLNREVRR------TGGRVLITLGDQ----DIDLSPSFVIFLSTRDPTVEFPPDLCSRVT 3697
L+ +V+ G R+ + L ++ +L + ++F D S +
Sbjct: 1256 KLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLES 1315
Query: 3698 FVNFTVTRSSLQSQCLNEV-LKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLL---QAL 3753
T+ LQ + ++ L + ++E+++ L + Q E + + LEK +L L
Sbjct: 1316 --QLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
Query: 3754 NEVKGRILDDDTIITTLENLK----REAAEVTRKVEETDIVMQEVE 3795
+ K ++ DD I +LE K ++A +++++EE + ++E
Sbjct: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLE 1419
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 50.1 bits (118), Expect = 5e-05
Identities = 67/340 (19%), Positives = 147/340 (43%), Gaps = 50/340 (14%)
Query: 3185 NLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMV 3244
NL ++ + + H+ GL + +E +V+ELRR L++ + E+ + + +D L K +
Sbjct: 783 NLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIH--SPSDVLGKSL 840
Query: 3245 KDQQ------------EAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEA 3292
D Q E ++ +V +++QE++ QQE +A Q ++ ++ +EA
Sbjct: 841 ADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACER----ALEA 896
Query: 3293 QNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIV 3352
+ + K+QH ++ M N ++ L+S+ + G + ++
Sbjct: 897 R--MNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQE--------------A 940
Query: 3353 NFSAEEISDAIREKMKKNYMSNPSYNYEI------VNRASLACGPMVKWAIAQLNYA-DM 3405
+ E I +RE KK + + ++ + + A K A A+L A D
Sbjct: 941 DEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQ 1000
Query: 3406 LKRVEPLRNEL-QKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKAD 3464
LK + ++ Q+ ++ ++ ++ + + Q RDL + A + +L + + + +
Sbjct: 1001 LKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLE 1060
Query: 3465 LAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIA 3504
+ ++ +L+ EK +ET + Q + IA
Sbjct: 1061 MEKTGVGTGANSQVLEI--------EKLNETMERQRTEIA 1092
Score = 48.9 bits (115), Expect = 1e-04
Identities = 51/284 (17%), Positives = 123/284 (43%), Gaps = 29/284 (10%)
Query: 3186 LFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVK 3245
+F + E E ++ L +KE Q+E+ D + K ++ K AA ++++ + +
Sbjct: 1949 MFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQE 2008
Query: 3246 DQQEAEKKKVMSQEIQEQLHKQQEVIADKQ---MSVKEDLDKVEPAVIEAQNAVKSIKKQ 3302
+++ E + + + QL ++++ + +K ++++++ D + + ++ Q
Sbjct: 2009 EERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSM-------RADFSLLRNQ 2061
Query: 3303 HLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDA 3362
L E + A++K AL+ L ++ + KQ S I +E + A++ +
Sbjct: 2062 FLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKE---MATIELVAQDNHER 2118
Query: 3363 IREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDD 3422
R MK+ ++ Y Y + + N D+ +R + + ++ L+ +
Sbjct: 2119 ARRLMKE--LNQMQYEYTELKK-------------QMANQKDLERRQMEISDAMRTLKSE 2163
Query: 3423 AKDN-QQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADL 3465
KD + + Q + +L A + E L E +++K +L
Sbjct: 2164 VKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENL 2207
Score = 40.0 bits (92), Expect = 0.054
Identities = 63/316 (19%), Positives = 134/316 (42%), Gaps = 50/316 (15%)
Query: 3206 RKIKETVDQVEELRRDLRIKSQELEV-KNAAANDKLK--------KMVKDQQEAEKKKVM 3256
+ I E ++ E+ +++ K Q+L+V +N +KLK + ++ ++E+E+ K+
Sbjct: 1906 KDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLE 1965
Query: 3257 SQEI--QEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIK-------------- 3300
+ ++ +EQ H+ ++ + D+ K LD+V V+ A+ V++++
Sbjct: 1966 TSKVTLKEQQHQLEKELTDQ----KSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLS 2021
Query: 3301 --KQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEE 3358
K+ L E + LAL+ D+ +R+ + E S +E
Sbjct: 2022 QTKRQLSEREQQLVEKSGELLALQKEA---DSMRADFSLLRNQFLTERKKAEKQVASLKE 2078
Query: 3359 ISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLR----- 3413
R +++KN + N I + +AQ N+ + ++ L
Sbjct: 2079 ALKIQRSQLEKNLLEQKQENSCIQKEMATI------ELVAQDNHERARRLMKELNQMQYE 2132
Query: 3414 -NELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAA-VEAK 3471
EL+K + KD +++ E+ +R L++ + K+E + +L A +EA
Sbjct: 2133 YTELKKQMANQKDLERRQMEISDAMRTLKSEV---KDEIRTSLKNLNQFLPELPADLEAI 2189
Query: 3472 VNRSTALLKSLSAERE 3487
+ R+ L L + +E
Sbjct: 2190 LERNENLEGELESLKE 2205
Score = 39.7 bits (91), Expect = 0.070
Identities = 59/331 (17%), Positives = 131/331 (39%), Gaps = 27/331 (8%)
Query: 3189 EKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQ 3248
+ +++L+E L +G ++ E + + E++ L S + N +++ ++ +Q
Sbjct: 1619 QAKADLQEA---LRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQ 1675
Query: 3249 EAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVR 3308
E EK++ Q + Q+ K K +L + + + ++ +K QH V
Sbjct: 1676 EIEKEEENLQVVLRQMSKH-----------KTELKNILDMLQLENHELQGLKLQHDQRVS 1724
Query: 3309 SMANPPAAV---KLALESICLLLGE--STTDW-KQIRSIIMRENFIPTIVNFSAEEISDA 3362
+ AV KL LE++ + + +W KQ+ RE T + + + +
Sbjct: 1725 ELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVEC 1784
Query: 3363 IREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDD 3422
+ ++ + + ++ + + Q N + V L+ EL +L D
Sbjct: 1785 LSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRD 1844
Query: 3423 AKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAV----EAKVNRSTAL 3478
+ ++Q +++ ++ +EE A + K DL + ++ T L
Sbjct: 1845 KLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRL 1904
Query: 3479 LKSLSAERERWE---KTSETFKNQMSTIAGD 3506
K +S R+E K ET + Q+ + +
Sbjct: 1905 QKDISEWANRFEDCQKEEETKQQQLQVLQNE 1935
Score = 38.5 bits (88), Expect = 0.16
Identities = 62/336 (18%), Positives = 138/336 (41%), Gaps = 44/336 (13%)
Query: 3192 SELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQEL-EVKNAAANDKLKKMVKD---- 3246
++LE+++ ++ ++ E D++E+ + + ++E +++ A K+ + KD
Sbjct: 437 TQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYK 496
Query: 3247 ------------QQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQN 3294
+QEA ++ ++ ++++ +Q+ I D Q+++ + LD +P
Sbjct: 497 QLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAI-DSLDSKDPK-HSHMK 554
Query: 3295 AVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNF 3354
A KS K+Q L M ++ L+ I + + T + K + +
Sbjct: 555 AQKSGKEQQL---DIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQI------- 604
Query: 3355 SAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRN 3414
++A+++ ++ Y I +A+ A K + L VE R+
Sbjct: 605 ---AANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERD 661
Query: 3415 ELQKLEDDAKDNQ----------QKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKAD 3464
+L+ + DA++ + Q+ +EV ++ + ++ Y+ E ++ A
Sbjct: 662 QLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQ 721
Query: 3465 LAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQM 3500
L KV R T L SA + EK + KN +
Sbjct: 722 LKEELEKVTRLTQL--EQSALQAELEKERQALKNAL 755
Score = 37.4 bits (85), Expect = 0.35
Identities = 77/421 (18%), Positives = 162/421 (38%), Gaps = 52/421 (12%)
Query: 1078 KWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLS-------- 1129
+WQ L++ K AE++ V K + + K D W K++
Sbjct: 1755 EWQKQLLERDKREIERMTAESRA-LQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAA 1813
Query: 1130 -KFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITY--------VQSLKRKI 1180
+ +M SN+ + + K +QEL+Q + D S + ++ + V SL+ ++
Sbjct: 1814 EENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEEL 1873
Query: 1181 KQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEW-GAFNDIMRRKDS------AIQ 1233
+ + L + K + + EW F D + +++ +Q
Sbjct: 1874 ANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQ 1933
Query: 1234 QQVANLQMKIVQED-------RAVESRTTDLLTDWEKTKPVTGNLRPE---------EAL 1277
++ ++K+VQ++ + ES + L T K L E + L
Sbjct: 1934 NEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVL 1993
Query: 1278 QALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELS 1337
+ E + L+++ C ++ L T L ER Q +E+ +L + E
Sbjct: 1994 SKVLAAEERVRTLQEEERWCESLEKTLSQTKRQL----SEREQQLVEKSGELLALQKEAD 2049
Query: 1338 KVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKIN 1397
+ ++ Q + +K + + +L LK ++L + Q+ ++
Sbjct: 2050 SMRADFSLLRNQ--FLTERKKAEKQVASLKEALKIQRSQLEKNL---LEQKQENSCIQKE 2104
Query: 1398 MLVIELKSEALKDRHWKQLMKRLH-VNWVVSELTLGQIWDVDLQKNEAIVKDVLLVAQGE 1456
M IEL ++ +R ++LMK L+ + + +EL DL++ + + D + + E
Sbjct: 2105 MATIELVAQDNHERA-RRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSE 2163
Query: 1457 M 1457
+
Sbjct: 2164 V 2164
Score = 36.6 bits (83), Expect = 0.60
Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 24/128 (18%)
Query: 3171 ITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKE--TVDQVEELRRDLR---IK 3225
+T HYL F +FH + E E Q ++ E ++++VE L RDL I+
Sbjct: 231 VTLPHYLQF-----TIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIE 285
Query: 3226 SQEL---------EVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQM 3276
++EL E+KN DKL K +K +EA +K +E++ L+ + E++ K +
Sbjct: 286 TEELKSKQTRFLEEIKN---QDKLNKSLK--EEAMLQKQSCEELKSDLNTKNELLKQKTI 340
Query: 3277 SVKEDLDK 3284
+ K
Sbjct: 341 ELTRACQK 348
Score = 35.8 bits (81), Expect = 1.0
Identities = 22/95 (23%), Positives = 49/95 (51%), Gaps = 11/95 (11%)
Query: 3206 RKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLH 3265
R + +T EEL R ++QE V A+ +L+ + D ++ E+ K+ +EI ++++
Sbjct: 1468 RSLLQTESDAEELER----RAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEIN 1523
Query: 3266 K-------QQEVIADKQMSVKEDLDKVEPAVIEAQ 3293
K + ++ K+ + E+L K++ + A+
Sbjct: 1524 KIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAE 1558
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 49.7 bits (117), Expect = 7e-05
Identities = 58/265 (21%), Positives = 128/265 (48%), Gaps = 35/265 (13%)
Query: 3189 EKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQ 3248
+K ++EE+ HL +K+K T D++++ DL+ ++LE+ A+D +
Sbjct: 34 DKCKQVEEELTHLQ---KKLKGTEDELDKYSEDLKDAQEKLELTEKKASD-----AEGDV 85
Query: 3249 EAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVR 3308
A +++ Q ++E+L + QE +A + + L++ E A E++ +K I+ + + +
Sbjct: 86 AALNRRI--QLVEEELDRAQERLA----TALQKLEEAEKAADESERGMKVIENRAMKDEE 139
Query: 3309 SMANPPAAVKLALESICLLLGESTTDWKQI-RSIIMRENFIPTIVNFSAEEISDAIREKM 3367
M +K A + E+ ++++ R +++ E + AEE ++ K
Sbjct: 140 KMEIQEMQLKEAKH----IAEEADRKYEEVARKLVILEGELE-----RAEERAEVSELKC 190
Query: 3368 --KKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKD 3425
+ + N + N + + AS K++ + Y + +K L ++L++ E A+
Sbjct: 191 GDLEEELKNVTNNLKSLEAAS------EKYSEKEDKYEEEIKL---LSDKLKEAETRAEF 241
Query: 3426 NQQKANEVEQMIRDLEASIARYKEE 3450
++ ++E+ I DLE +A+ KEE
Sbjct: 242 AERTVAKLEKTIDDLEEKLAQAKEE 266
Score = 37.0 bits (84), Expect = 0.46
Identities = 54/258 (20%), Positives = 109/258 (42%), Gaps = 26/258 (10%)
Query: 3205 LRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQL 3264
+ IK+ + ++ + + ++++ E AA DK K++ ++ +KK + +++L
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKK---LKGTEDEL 57
Query: 3265 HKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKK--QHLVEVRSMANPPAAVKL-AL 3321
K E + D Q E L+ E +A+ V ++ + Q + E A A L L
Sbjct: 58 DKYSEDLKDAQ----EKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKL 113
Query: 3322 ESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEI 3381
E ES K I + M++ I +E E +K YE
Sbjct: 114 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK---------YEE 164
Query: 3382 VNRASLACGPMVKWA-----IAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQM 3436
V R + ++ A +++L D+ + ++ + N L+ LE ++ +K ++ E+
Sbjct: 165 VARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEE 224
Query: 3437 IRDLEASI--ARYKEEYA 3452
I+ L + A + E+A
Sbjct: 225 IKLLSDKLKEAETRAEFA 242
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 166,068,098
Number of Sequences: 37866
Number of extensions: 7279493
Number of successful extensions: 30716
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 476
Number of HSP's that attempted gapping in prelim test: 24390
Number of HSP's gapped (non-prelim): 5582
length of query: 4646
length of database: 18,247,518
effective HSP length: 124
effective length of query: 4522
effective length of database: 13,552,134
effective search space: 61282749948
effective search space used: 61282749948
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.