Guide to the Human Genome
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Search of human proteins with 33239443

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens]
         (241 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens]             499   e-141
gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens]              499   e-141
gi|27764867 synaptophysin [Homo sapiens]                              208   3e-54
gi|194018518 synaptoporin isoform 1 [Homo sapiens]                    201   4e-52
gi|105554421 mitsugumin 29 [Homo sapiens]                             198   3e-51
gi|21389481 synaptoporin isoform 2 [Homo sapiens]                     185   3e-47
gi|54792073 mucolipin 2 [Homo sapiens]                                 31   0.84 
gi|45594240 limbic system-associated membrane protein [Homo sapi...    30   1.4  
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]      30   2.5  
gi|6631112 synaptogyrin 3 [Homo sapiens]                               29   4.2  
gi|119964726 insulin-like growth factor 2 receptor precursor [Ho...    28   5.5  
gi|14140236 solute carrier family 5 (low affinity glucose cotran...    28   5.5  
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]            28   7.1  
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]            28   7.1  
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]            28   7.1  
gi|7661916 lysosomal protein transmembrane 4 alpha [Homo sapiens]      28   9.3  
gi|51100974 myosin ID [Homo sapiens]                                   28   9.3  
gi|52218856 olfactory receptor, family 10, subfamily Z, member 1...    28   9.3  

>gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens]
          Length = 241

 Score =  499 bits (1284), Expect = e-141
 Identities = 241/241 (100%), Positives = 241/241 (100%)

Query: 1   MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 60
           MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF
Sbjct: 1   MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 60

Query: 61  GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG 120
           GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG
Sbjct: 61  GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG 120

Query: 121 YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV 180
           YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV
Sbjct: 121 YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV 180

Query: 181 LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG 240
           LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG
Sbjct: 181 LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG 240

Query: 241 I 241
           I
Sbjct: 241 I 241


>gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens]
          Length = 259

 Score =  499 bits (1284), Expect = e-141
 Identities = 241/241 (100%), Positives = 241/241 (100%)

Query: 1   MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 60
           MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF
Sbjct: 19  MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 78

Query: 61  GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG 120
           GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG
Sbjct: 79  GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG 138

Query: 121 YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV 180
           YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV
Sbjct: 139 YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV 198

Query: 181 LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG 240
           LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG
Sbjct: 199 LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG 258

Query: 241 I 241
           I
Sbjct: 259 I 259


>gi|27764867 synaptophysin [Homo sapiens]
          Length = 313

 Score =  208 bits (530), Expect = 3e-54
 Identities = 103/229 (44%), Positives = 143/229 (62%), Gaps = 5/229 (2%)

Query: 11  LKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEAS 70
           +KEPLGF+KVL+W+ +IFAFATCG + G+ ++ V+C      + ++   F YPFRL++  
Sbjct: 22  VKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANKTESDLSIEVEFEYPFRLHQVY 81

Query: 71  FQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRK 130
           F  P     C        L+GDYSSSA+F+VT AVF FLY + AL  Y+   + Y ++ K
Sbjct: 82  FDAPT----CRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNK 137

Query: 131 LPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKKAVLCYFGSVTS 189
            PM+DF+ T V  F+WLVS+SAWAK L+D+K+AT   NII E+P C++    C       
Sbjct: 138 GPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPVCRQTGNTCKELRDPV 197

Query: 190 MGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPP 238
              LN SV+FGFLN++LW GN WFV+KET   +P   + P +    P P
Sbjct: 198 TSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAPEKQPAP 246


>gi|194018518 synaptoporin isoform 1 [Homo sapiens]
          Length = 285

 Score =  201 bits (512), Expect = 4e-52
 Identities = 104/235 (44%), Positives = 149/235 (63%), Gaps = 15/235 (6%)

Query: 11  LKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEAS 70
           LKEPL F++ LE + +IFAFATCGG+ G   + V+C      N ++   F YPFRL++ +
Sbjct: 16  LKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVT 75

Query: 71  FQPPPGVNICDVNWKDYV-LIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSR 129
           F+ P     C+   +  + LIGD SSSA+F+VT AVF FLY +AA ++Y+ + + Y ++ 
Sbjct: 76  FEVPT----CEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENN 131

Query: 130 KLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKKAVLCYFGSVT 188
           + P+IDF+VT+V +FLWLV +SAWAK L+D+K+AT    ++  +  CK+ +  C      
Sbjct: 132 RGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSP 191

Query: 189 SMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNT---------SAPHSQGG 234
            M SLN SV+FGFLN ILW GN WFV+KET  HS             S+ ++QGG
Sbjct: 192 VMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGG 246


>gi|105554421 mitsugumin 29 [Homo sapiens]
          Length = 272

 Score =  198 bits (504), Expect = 3e-51
 Identities = 92/214 (42%), Positives = 139/214 (64%), Gaps = 7/214 (3%)

Query: 11  LKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEAS 70
           L+EPLGFIKVL+W+ +IFAF +CG + G+T   V C     +  ++   FGYPFRL+   
Sbjct: 31  LEEPLGFIKVLQWLFAIFAFGSCGSYSGETGAMVRCNNEAKDVSSIIVAFGYPFRLHRIQ 90

Query: 71  FQPPPGVNICDV--NWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDS 128
           ++ P    +CD   + K   L+GD+S+ A+F+VT  +F F Y +AAL++Y+ + +LY ++
Sbjct: 91  YEMP----LCDEESSSKTMHLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHNLYTEN 146

Query: 129 RKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIAT-GHNIIDELPPCKKKAVLCYFGSV 187
           ++ P++DF VT+  TF WLV+ +AW K LTD+K AT   ++   +  C  +  +C  G+ 
Sbjct: 147 KRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGAT 206

Query: 188 TSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLH 221
            SMG  N+SV+FGF+N  LW GN WFV+KET  H
Sbjct: 207 PSMGLANISVLFGFINFFLWAGNCWFVFKETPWH 240


>gi|21389481 synaptoporin isoform 2 [Homo sapiens]
          Length = 265

 Score =  185 bits (470), Expect = 3e-47
 Identities = 96/220 (43%), Positives = 138/220 (62%), Gaps = 15/220 (6%)

Query: 26  SIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEASFQPPPGVNICDVNWK 85
           +IFAFATCGG+ G   + V+C      N ++   F YPFRL++ +F+ P     C+   +
Sbjct: 11  AIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPT----CEGKER 66

Query: 86  DYV-LIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRKLPMIDFVVTLVATF 144
             + LIGD SSSA+F+VT AVF FLY +AA ++Y+ + + Y ++ + P+IDF+VT+V +F
Sbjct: 67  QKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSF 126

Query: 145 LWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKKAVLCYFGSVTSMGSLNVSVIFGFLN 203
           LWLV +SAWAK L+D+K+AT    ++  +  CK+ +  C       M SLN SV+FGFLN
Sbjct: 127 LWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVFGFLN 186

Query: 204 MILWGGNAWFVYKETSLHSPSNT---------SAPHSQGG 234
            ILW GN WFV+KET  HS             S+ ++QGG
Sbjct: 187 FILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGG 226


>gi|54792073 mucolipin 2 [Homo sapiens]
          Length = 566

 Score = 31.2 bits (69), Expect = 0.84
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 85  KDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRK 130
           KD  + G    +AQ+ + F  FV + C+A+L+L      L L  RK
Sbjct: 275 KDLNIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRK 320


>gi|45594240 limbic system-associated membrane protein [Homo
           sapiens]
          Length = 338

 Score = 30.4 bits (67), Expect = 1.4
 Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 39  QTEIQVNCPPAVTENKTVTATFGYPFRLN-EASFQPPP 75
           Q ++ VN PP +TE+K+  AT G    L  EAS  P P
Sbjct: 210 QVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAP 247


>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
          Length = 782

 Score = 29.6 bits (65), Expect = 2.5
 Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 12/112 (10%)

Query: 18  IKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTE-NKTVTATFGYPFR----LNEASFQ 72
           I VL  IA+    A    F  +   +    P + E N TV    GY        +   FQ
Sbjct: 605 IGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQ 664

Query: 73  PPPGV----NICDVNWKDYVLIGDYSSSAQFYVTFAV---FVFLYCIAALLL 117
            P G+    N+    ++DY    DY+ S QF+   A+   FV L+   AL +
Sbjct: 665 DPDGIEGSENVTLCRYRDYRNPPDYNFSEQFWFLLAIRLAFVILFEHVALCI 716


>gi|6631112 synaptogyrin 3 [Homo sapiens]
          Length = 229

 Score = 28.9 bits (63), Expect = 4.2
 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 6/68 (8%)

Query: 94  SSSAQFYVTFAVFVFLYCIAALLLYVGY--TSLYLDSRKLPMIDFVVTLVATFLWLVS-- 149
           + + +F V   +  FL C A LLL V +   S   D R+  ++D   + + +FLW V   
Sbjct: 65  AGACRFGVALGLGAFLACAAFLLLDVRFQQISSVRDRRRAVLLDLGFSGLWSFLWFVGFC 124

Query: 150 --TSAWAK 155
             T+ W +
Sbjct: 125 FLTNQWQR 132


>gi|119964726 insulin-like growth factor 2 receptor precursor [Homo
           sapiens]
          Length = 2491

 Score = 28.5 bits (62), Expect = 5.5
 Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 2/33 (6%)

Query: 2   SGFQINLNPLKEPLGFIKVLEWIASIFAFATCG 34
           SGF  NLNPL    G+   +  I  IF F  CG
Sbjct: 941 SGFVFNLNPLNSSQGY--NVSGIGKIFMFNVCG 971


>gi|14140236 solute carrier family 5 (low affinity glucose
           cotransporter), member 4 [Homo sapiens]
          Length = 659

 Score = 28.5 bits (62), Expect = 5.5
 Identities = 13/30 (43%), Positives = 17/30 (56%)

Query: 28  FAFATCGGFKGQTEIQVNCPPAVTENKTVT 57
           FAF   GG++  TE  VN  P+V E   +T
Sbjct: 221 FAFNEVGGYESFTEKYVNATPSVVEGDNLT 250


>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 30/132 (22%), Positives = 52/132 (39%), Gaps = 13/132 (9%)

Query: 56  VTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAAL 115
           VT  +GY    N   F     +N     W DY  +    S  +  VTF++  F+      
Sbjct: 270 VTFPYGYHAGFNHG-FNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFV-----R 323

Query: 116 LLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPP 174
           +L      L+   + L ++D++   VA        S W + +   + A G  ++ + +  
Sbjct: 324 ILQPESYELWKHRQDLTVVDYMEPRVAE---SQEPSNWREDIALRRAALGLRHLRNHITS 380

Query: 175 CKKKAV---LCY 183
           C  + V   LCY
Sbjct: 381 CPTRTVAPRLCY 392


>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 30/132 (22%), Positives = 52/132 (39%), Gaps = 13/132 (9%)

Query: 56  VTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAAL 115
           VT  +GY    N   F     +N     W DY  +    S  +  VTF++  F+      
Sbjct: 270 VTFPYGYHAGFNHG-FNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFV-----R 323

Query: 116 LLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPP 174
           +L      L+   + L ++D++   VA        S W + +   + A G  ++ + +  
Sbjct: 324 ILQPESYELWKHRQDLTVVDYMEPRVAE---SQEPSNWREDIALRRAALGLRHLRNHITS 380

Query: 175 CKKKAV---LCY 183
           C  + V   LCY
Sbjct: 381 CPTRTVAPRLCY 392


>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 30/132 (22%), Positives = 52/132 (39%), Gaps = 13/132 (9%)

Query: 56  VTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAAL 115
           VT  +GY    N   F     +N     W DY  +    S  +  VTF++  F+      
Sbjct: 270 VTFPYGYHAGFNHG-FNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFV-----R 323

Query: 116 LLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPP 174
           +L      L+   + L ++D++   VA        S W + +   + A G  ++ + +  
Sbjct: 324 ILQPESYELWKHRQDLTVVDYMEPRVAE---SQEPSNWREDIALRRAALGLRHLRNHITS 380

Query: 175 CKKKAV---LCY 183
           C  + V   LCY
Sbjct: 381 CPTRTVAPRLCY 392


>gi|7661916 lysosomal protein transmembrane 4 alpha [Homo sapiens]
          Length = 233

 Score = 27.7 bits (60), Expect = 9.3
 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 10/48 (20%)

Query: 75  PGVNICDVNWKDYVLIGDYSSSAQFY----VTFAVFVFLYCIAALLLY 118
           P VNI       Y +IG+Y SS +      V FAV V ++ I+++L+Y
Sbjct: 58  PAVNI------QYEVIGNYYSSERMADNACVLFAVSVLMFIISSMLVY 99


>gi|51100974 myosin ID [Homo sapiens]
          Length = 1006

 Score = 27.7 bits (60), Expect = 9.3
 Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 109 LYCIAALLLYVGYTSLYLDSRKLPMIDF--VVTLVATFLWLVSTSAWAKALTDIKIATGH 166
           +Y I A +L++G     +D    P+I+   VV+++A  L    T    KAL    +ATG 
Sbjct: 267 VYKILAAILHLGNLKFVVDG-DTPLIENGKVVSIIAELL-STKTDMVEKALLYRTVATGR 324

Query: 167 NIIDE 171
           +IID+
Sbjct: 325 DIIDK 329


>gi|52218856 olfactory receptor, family 10, subfamily Z, member 1
           [Homo sapiens]
          Length = 313

 Score = 27.7 bits (60), Expect = 9.3
 Identities = 11/30 (36%), Positives = 19/30 (63%)

Query: 83  NWKDYVLIGDYSSSAQFYVTFAVFVFLYCI 112
           +W+D+V +G  SS     + FA+F+ LY +
Sbjct: 8   SWRDFVFLGFSSSGELQLLLFALFLSLYLV 37


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,068,963
Number of Sequences: 37866
Number of extensions: 406075
Number of successful extensions: 949
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 930
Number of HSP's gapped (non-prelim): 19
length of query: 241
length of database: 18,247,518
effective HSP length: 99
effective length of query: 142
effective length of database: 14,498,784
effective search space: 2058827328
effective search space used: 2058827328
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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