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Search of human proteins with 33239443
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens]
(241 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens] 499 e-141
gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens] 499 e-141
gi|27764867 synaptophysin [Homo sapiens] 208 3e-54
gi|194018518 synaptoporin isoform 1 [Homo sapiens] 201 4e-52
gi|105554421 mitsugumin 29 [Homo sapiens] 198 3e-51
gi|21389481 synaptoporin isoform 2 [Homo sapiens] 185 3e-47
gi|54792073 mucolipin 2 [Homo sapiens] 31 0.84
gi|45594240 limbic system-associated membrane protein [Homo sapi... 30 1.4
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] 30 2.5
gi|6631112 synaptogyrin 3 [Homo sapiens] 29 4.2
gi|119964726 insulin-like growth factor 2 receptor precursor [Ho... 28 5.5
gi|14140236 solute carrier family 5 (low affinity glucose cotran... 28 5.5
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens] 28 7.1
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens] 28 7.1
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens] 28 7.1
gi|7661916 lysosomal protein transmembrane 4 alpha [Homo sapiens] 28 9.3
gi|51100974 myosin ID [Homo sapiens] 28 9.3
gi|52218856 olfactory receptor, family 10, subfamily Z, member 1... 28 9.3
>gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens]
Length = 241
Score = 499 bits (1284), Expect = e-141
Identities = 241/241 (100%), Positives = 241/241 (100%)
Query: 1 MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 60
MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF
Sbjct: 1 MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 60
Query: 61 GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG 120
GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG
Sbjct: 61 GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG 120
Query: 121 YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV 180
YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV
Sbjct: 121 YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV 180
Query: 181 LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG 240
LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG
Sbjct: 181 LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG 240
Query: 241 I 241
I
Sbjct: 241 I 241
>gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens]
Length = 259
Score = 499 bits (1284), Expect = e-141
Identities = 241/241 (100%), Positives = 241/241 (100%)
Query: 1 MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 60
MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF
Sbjct: 19 MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 78
Query: 61 GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG 120
GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG
Sbjct: 79 GYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVG 138
Query: 121 YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV 180
YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV
Sbjct: 139 YTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHNIIDELPPCKKKAV 198
Query: 181 LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG 240
LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG
Sbjct: 199 LCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTG 258
Query: 241 I 241
I
Sbjct: 259 I 259
>gi|27764867 synaptophysin [Homo sapiens]
Length = 313
Score = 208 bits (530), Expect = 3e-54
Identities = 103/229 (44%), Positives = 143/229 (62%), Gaps = 5/229 (2%)
Query: 11 LKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEAS 70
+KEPLGF+KVL+W+ +IFAFATCG + G+ ++ V+C + ++ F YPFRL++
Sbjct: 22 VKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANKTESDLSIEVEFEYPFRLHQVY 81
Query: 71 FQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRK 130
F P C L+GDYSSSA+F+VT AVF FLY + AL Y+ + Y ++ K
Sbjct: 82 FDAPT----CRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNK 137
Query: 131 LPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKKAVLCYFGSVTS 189
PM+DF+ T V F+WLVS+SAWAK L+D+K+AT NII E+P C++ C
Sbjct: 138 GPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPVCRQTGNTCKELRDPV 197
Query: 190 MGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPP 238
LN SV+FGFLN++LW GN WFV+KET +P + P + P P
Sbjct: 198 TSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAPEKQPAP 246
>gi|194018518 synaptoporin isoform 1 [Homo sapiens]
Length = 285
Score = 201 bits (512), Expect = 4e-52
Identities = 104/235 (44%), Positives = 149/235 (63%), Gaps = 15/235 (6%)
Query: 11 LKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEAS 70
LKEPL F++ LE + +IFAFATCGG+ G + V+C N ++ F YPFRL++ +
Sbjct: 16 LKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVT 75
Query: 71 FQPPPGVNICDVNWKDYV-LIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSR 129
F+ P C+ + + LIGD SSSA+F+VT AVF FLY +AA ++Y+ + + Y ++
Sbjct: 76 FEVPT----CEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENN 131
Query: 130 KLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKKAVLCYFGSVT 188
+ P+IDF+VT+V +FLWLV +SAWAK L+D+K+AT ++ + CK+ + C
Sbjct: 132 RGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSP 191
Query: 189 SMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNT---------SAPHSQGG 234
M SLN SV+FGFLN ILW GN WFV+KET HS S+ ++QGG
Sbjct: 192 VMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGG 246
>gi|105554421 mitsugumin 29 [Homo sapiens]
Length = 272
Score = 198 bits (504), Expect = 3e-51
Identities = 92/214 (42%), Positives = 139/214 (64%), Gaps = 7/214 (3%)
Query: 11 LKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEAS 70
L+EPLGFIKVL+W+ +IFAF +CG + G+T V C + ++ FGYPFRL+
Sbjct: 31 LEEPLGFIKVLQWLFAIFAFGSCGSYSGETGAMVRCNNEAKDVSSIIVAFGYPFRLHRIQ 90
Query: 71 FQPPPGVNICDV--NWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDS 128
++ P +CD + K L+GD+S+ A+F+VT +F F Y +AAL++Y+ + +LY ++
Sbjct: 91 YEMP----LCDEESSSKTMHLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHNLYTEN 146
Query: 129 RKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIAT-GHNIIDELPPCKKKAVLCYFGSV 187
++ P++DF VT+ TF WLV+ +AW K LTD+K AT ++ + C + +C G+
Sbjct: 147 KRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGAT 206
Query: 188 TSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLH 221
SMG N+SV+FGF+N LW GN WFV+KET H
Sbjct: 207 PSMGLANISVLFGFINFFLWAGNCWFVFKETPWH 240
>gi|21389481 synaptoporin isoform 2 [Homo sapiens]
Length = 265
Score = 185 bits (470), Expect = 3e-47
Identities = 96/220 (43%), Positives = 138/220 (62%), Gaps = 15/220 (6%)
Query: 26 SIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEASFQPPPGVNICDVNWK 85
+IFAFATCGG+ G + V+C N ++ F YPFRL++ +F+ P C+ +
Sbjct: 11 AIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPT----CEGKER 66
Query: 86 DYV-LIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRKLPMIDFVVTLVATF 144
+ LIGD SSSA+F+VT AVF FLY +AA ++Y+ + + Y ++ + P+IDF+VT+V +F
Sbjct: 67 QKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSF 126
Query: 145 LWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKKAVLCYFGSVTSMGSLNVSVIFGFLN 203
LWLV +SAWAK L+D+K+AT ++ + CK+ + C M SLN SV+FGFLN
Sbjct: 127 LWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVFGFLN 186
Query: 204 MILWGGNAWFVYKETSLHSPSNT---------SAPHSQGG 234
ILW GN WFV+KET HS S+ ++QGG
Sbjct: 187 FILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGG 226
>gi|54792073 mucolipin 2 [Homo sapiens]
Length = 566
Score = 31.2 bits (69), Expect = 0.84
Identities = 16/46 (34%), Positives = 24/46 (52%)
Query: 85 KDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRK 130
KD + G +AQ+ + F FV + C+A+L+L L L RK
Sbjct: 275 KDLNIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRK 320
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 30.4 bits (67), Expect = 1.4
Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 39 QTEIQVNCPPAVTENKTVTATFGYPFRLN-EASFQPPP 75
Q ++ VN PP +TE+K+ AT G L EAS P P
Sbjct: 210 QVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAP 247
>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
Length = 782
Score = 29.6 bits (65), Expect = 2.5
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 18 IKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTE-NKTVTATFGYPFR----LNEASFQ 72
I VL IA+ A F + + P + E N TV GY + FQ
Sbjct: 605 IGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQ 664
Query: 73 PPPGV----NICDVNWKDYVLIGDYSSSAQFYVTFAV---FVFLYCIAALLL 117
P G+ N+ ++DY DY+ S QF+ A+ FV L+ AL +
Sbjct: 665 DPDGIEGSENVTLCRYRDYRNPPDYNFSEQFWFLLAIRLAFVILFEHVALCI 716
>gi|6631112 synaptogyrin 3 [Homo sapiens]
Length = 229
Score = 28.9 bits (63), Expect = 4.2
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 6/68 (8%)
Query: 94 SSSAQFYVTFAVFVFLYCIAALLLYVGY--TSLYLDSRKLPMIDFVVTLVATFLWLVS-- 149
+ + +F V + FL C A LLL V + S D R+ ++D + + +FLW V
Sbjct: 65 AGACRFGVALGLGAFLACAAFLLLDVRFQQISSVRDRRRAVLLDLGFSGLWSFLWFVGFC 124
Query: 150 --TSAWAK 155
T+ W +
Sbjct: 125 FLTNQWQR 132
>gi|119964726 insulin-like growth factor 2 receptor precursor [Homo
sapiens]
Length = 2491
Score = 28.5 bits (62), Expect = 5.5
Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 2/33 (6%)
Query: 2 SGFQINLNPLKEPLGFIKVLEWIASIFAFATCG 34
SGF NLNPL G+ + I IF F CG
Sbjct: 941 SGFVFNLNPLNSSQGY--NVSGIGKIFMFNVCG 971
>gi|14140236 solute carrier family 5 (low affinity glucose
cotransporter), member 4 [Homo sapiens]
Length = 659
Score = 28.5 bits (62), Expect = 5.5
Identities = 13/30 (43%), Positives = 17/30 (56%)
Query: 28 FAFATCGGFKGQTEIQVNCPPAVTENKTVT 57
FAF GG++ TE VN P+V E +T
Sbjct: 221 FAFNEVGGYESFTEKYVNATPSVVEGDNLT 250
>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 28.1 bits (61), Expect = 7.1
Identities = 30/132 (22%), Positives = 52/132 (39%), Gaps = 13/132 (9%)
Query: 56 VTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAAL 115
VT +GY N F +N W DY + S + VTF++ F+
Sbjct: 270 VTFPYGYHAGFNHG-FNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFV-----R 323
Query: 116 LLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPP 174
+L L+ + L ++D++ VA S W + + + A G ++ + +
Sbjct: 324 ILQPESYELWKHRQDLTVVDYMEPRVAE---SQEPSNWREDIALRRAALGLRHLRNHITS 380
Query: 175 CKKKAV---LCY 183
C + V LCY
Sbjct: 381 CPTRTVAPRLCY 392
>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 28.1 bits (61), Expect = 7.1
Identities = 30/132 (22%), Positives = 52/132 (39%), Gaps = 13/132 (9%)
Query: 56 VTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAAL 115
VT +GY N F +N W DY + S + VTF++ F+
Sbjct: 270 VTFPYGYHAGFNHG-FNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFV-----R 323
Query: 116 LLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPP 174
+L L+ + L ++D++ VA S W + + + A G ++ + +
Sbjct: 324 ILQPESYELWKHRQDLTVVDYMEPRVAE---SQEPSNWREDIALRRAALGLRHLRNHITS 380
Query: 175 CKKKAV---LCY 183
C + V LCY
Sbjct: 381 CPTRTVAPRLCY 392
>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 28.1 bits (61), Expect = 7.1
Identities = 30/132 (22%), Positives = 52/132 (39%), Gaps = 13/132 (9%)
Query: 56 VTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAAL 115
VT +GY N F +N W DY + S + VTF++ F+
Sbjct: 270 VTFPYGYHAGFNHG-FNCAEAINFATPRWIDYGKVASQCSCGEARVTFSMDAFV-----R 323
Query: 116 LLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPP 174
+L L+ + L ++D++ VA S W + + + A G ++ + +
Sbjct: 324 ILQPESYELWKHRQDLTVVDYMEPRVAE---SQEPSNWREDIALRRAALGLRHLRNHITS 380
Query: 175 CKKKAV---LCY 183
C + V LCY
Sbjct: 381 CPTRTVAPRLCY 392
>gi|7661916 lysosomal protein transmembrane 4 alpha [Homo sapiens]
Length = 233
Score = 27.7 bits (60), Expect = 9.3
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 10/48 (20%)
Query: 75 PGVNICDVNWKDYVLIGDYSSSAQFY----VTFAVFVFLYCIAALLLY 118
P VNI Y +IG+Y SS + V FAV V ++ I+++L+Y
Sbjct: 58 PAVNI------QYEVIGNYYSSERMADNACVLFAVSVLMFIISSMLVY 99
>gi|51100974 myosin ID [Homo sapiens]
Length = 1006
Score = 27.7 bits (60), Expect = 9.3
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 109 LYCIAALLLYVGYTSLYLDSRKLPMIDF--VVTLVATFLWLVSTSAWAKALTDIKIATGH 166
+Y I A +L++G +D P+I+ VV+++A L T KAL +ATG
Sbjct: 267 VYKILAAILHLGNLKFVVDG-DTPLIENGKVVSIIAELL-STKTDMVEKALLYRTVATGR 324
Query: 167 NIIDE 171
+IID+
Sbjct: 325 DIIDK 329
>gi|52218856 olfactory receptor, family 10, subfamily Z, member 1
[Homo sapiens]
Length = 313
Score = 27.7 bits (60), Expect = 9.3
Identities = 11/30 (36%), Positives = 19/30 (63%)
Query: 83 NWKDYVLIGDYSSSAQFYVTFAVFVFLYCI 112
+W+D+V +G SS + FA+F+ LY +
Sbjct: 8 SWRDFVFLGFSSSGELQLLLFALFLSLYLV 37
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,068,963
Number of Sequences: 37866
Number of extensions: 406075
Number of successful extensions: 949
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 930
Number of HSP's gapped (non-prelim): 19
length of query: 241
length of database: 18,247,518
effective HSP length: 99
effective length of query: 142
effective length of database: 14,498,784
effective search space: 2058827328
effective search space used: 2058827328
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.