Guide to the Human Genome
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Name: PKM2 Sequence: fasta or formatted (531aa) NCBI GI: 33286422
Description:

pyruvate kinase, muscle isoform M1

Referenced in:

Glycolysis
Thyroid and Thyroid Hormone Receptor

Other entries for this name:
alt prot [531aa] pyruvate kinase, muscle isoform M2
alt mRNA [531aa] pyruvate kinase, muscle isoform M1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.4         55           3
 C cysteine            1.7          9           1
 D aspartate           5.5         29           2
 E glutamate           7.2         38           2
 F phenylalanine       3.2         17           2
 G glycine             7.5         40           2
 H histidine           2.4         13           1
 I isoleucine          6.8         36           2
 K lysine              7.0         37           2
 L leucine             7.3         39           1
 M methionine          3.8         20           2
 N asparagine          3.2         17           1
 P proline             4.1         22           2
 Q glutamine           2.6         14           2
 R arginine            5.8         31           2
 S serine              5.6         30           2
 T threonine           5.1         27           1
 V valine              8.5         45           2
 W tryptophan          0.6          3           1
 Y tyrosine            1.7          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   pyruvate kinase, muscle isoform M1 
PKM2                  1.000   pyruvate kinase, muscle isoform M1 
PKM2                  0.961   pyruvate kinase, muscle isoform M2 
PKLR                  0.703   pyruvate kinase, liver and RBC isoform 2 
PKLR                  0.703   pyruvate kinase, liver and RBC isoform 1 
LOC652797             0.607   PREDICTED: similar to pyruvate kinase, muscle [Homo...
NOL4                  0.009   nucleolar protein 4 
TACO1                 0.007   translational activator of mitochondrially encoded c...
TFRC                  0.006   transferrin receptor 
TFRC                  0.006   transferrin receptor 
GC                    0.004   vitamin D-binding protein precursor 
PDRG1                 0.004   p53 and DNA damage-regulated protein 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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