Search of human proteins with 123173766

Search of human proteins with 123173766

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|123173766 tubulin polyglutamylase complex subunit 1 [Homo
sapiens]
         (290 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|123173766 tubulin polyglutamylase complex subunit 1 [Homo sap...   565   e-161
gi|47132583 cAMP-dependent protein kinase, regulatory subunit al...    39   0.005
gi|47132581 cAMP-dependent protein kinase, regulatory subunit al...    39   0.005
gi|4506063 cAMP-dependent protein kinase, regulatory subunit alp...    39   0.005
gi|38257139 protein kinase, cAMP-dependent, regulatory, type I, ...    31   1.1  
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s...    31   1.5  
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa...    31   1.5  
gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo ...    30   3.2  
gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo ...    30   3.2  
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     29   4.2  
gi|7662230 ring finger protein 40 [Homo sapiens]                       29   4.2  
gi|187608615 tyrosine kinase 2 [Homo sapiens]                          28   9.4  

>gi|123173766 tubulin polyglutamylase complex subunit 1 [Homo
           sapiens]
          Length = 290

 Score =  565 bits (1455), Expect = e-161
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MAAVEKRRQAVPPPAGFTDSGRQSVSRAAGAAESEEDFLRQVGVTEMLRAALLKVLEARP 60
           MAAVEKRRQAVPPPAGFTDSGRQSVSRAAGAAESEEDFLRQVGVTEMLRAALLKVLEARP
Sbjct: 1   MAAVEKRRQAVPPPAGFTDSGRQSVSRAAGAAESEEDFLRQVGVTEMLRAALLKVLEARP 60

Query: 61  EEPIAFLAHYFENMGLRSPVNGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRAAFNNNV 120
           EEPIAFLAHYFENMGLRSPVNGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRAAFNNNV
Sbjct: 61  EEPIAFLAHYFENMGLRSPVNGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRAAFNNNV 120

Query: 121 SVAYECLSAGGRRKRPGLDGRTYSELLRRICRDGQAPEEVVAPLLRKVQCRDHEAVPLSV 180
           SVAYECLSAGGRRKRPGLDGRTYSELLRRICRDGQAPEEVVAPLLRKVQCRDHEAVPLSV
Sbjct: 121 SVAYECLSAGGRRKRPGLDGRTYSELLRRICRDGQAPEEVVAPLLRKVQCRDHEAVPLSV 180

Query: 181 FRAGTLTCFVLLEFVARAGALFQLLEDSAAAVADRRVGQAVLDTLEGALQASDAAAPARF 240
           FRAGTLTCFVLLEFVARAGALFQLLEDSAAAVADRRVGQAVLDTLEGALQASDAAAPARF
Sbjct: 181 FRAGTLTCFVLLEFVARAGALFQLLEDSAAAVADRRVGQAVLDTLEGALQASDAAAPARF 240

Query: 241 LEAGSRLGPDSLALALDRAVGGRRPSAPMTREEFLERAAALFIAKVKPVG 290
           LEAGSRLGPDSLALALDRAVGGRRPSAPMTREEFLERAAALFIAKVKPVG
Sbjct: 241 LEAGSRLGPDSLALALDRAVGGRRPSAPMTREEFLERAAALFIAKVKPVG 290


>gi|47132583 cAMP-dependent protein kinase, regulatory subunit
          alpha 1 [Homo sapiens]
          Length = 381

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 17/56 (30%), Positives = 34/56 (60%)

Query: 19 DSGRQSVSRAAGAAESEEDFLRQVGVTEMLRAALLKVLEARPEEPIAFLAHYFENM 74
          +SG  + S  A +    E ++++  +  +L+ +++++  ARPE P+AFL  YFE +
Sbjct: 2  ESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERL 57


>gi|47132581 cAMP-dependent protein kinase, regulatory subunit
          alpha 1 [Homo sapiens]
          Length = 381

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 17/56 (30%), Positives = 34/56 (60%)

Query: 19 DSGRQSVSRAAGAAESEEDFLRQVGVTEMLRAALLKVLEARPEEPIAFLAHYFENM 74
          +SG  + S  A +    E ++++  +  +L+ +++++  ARPE P+AFL  YFE +
Sbjct: 2  ESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERL 57


>gi|4506063 cAMP-dependent protein kinase, regulatory subunit
          alpha 1 [Homo sapiens]
          Length = 381

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 17/56 (30%), Positives = 34/56 (60%)

Query: 19 DSGRQSVSRAAGAAESEEDFLRQVGVTEMLRAALLKVLEARPEEPIAFLAHYFENM 74
          +SG  + S  A +    E ++++  +  +L+ +++++  ARPE P+AFL  YFE +
Sbjct: 2  ESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERL 57


>gi|38257139 protein kinase, cAMP-dependent, regulatory, type I,
           beta [Homo sapiens]
          Length = 381

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 29/123 (23%)

Query: 31  AAESEED--------FLRQVGVTEMLRAALLKVLEARPEEPIAFLAHYFENMGLRSPVNG 82
           A  SEED        +++  G+ ++L+  ++ +  ++PE P+ FL  +FE +        
Sbjct: 6   ACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKL-------- 57

Query: 83  GAGEPPGQLLLQQQRLGRALWHLRLAHHSQRAAFNNNVSVAYECLSAGGRRKRPGLDGRT 142
              E   Q+L +Q+             +SQ  + +  VS          RR+R G+    
Sbjct: 58  -EKEENRQILARQK------------SNSQSDSHDEEVSPTPPNPVVKARRRRGGVSAEV 104

Query: 143 YSE 145
           Y+E
Sbjct: 105 YTE 107


>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
           sapiens]
          Length = 1235

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 14/32 (43%), Positives = 17/32 (53%)

Query: 10  AVPPPAGFTDSGRQSVSRAAGAAESEEDFLRQ 41
           A+PPP   T    Q     AG+  SE+D LRQ
Sbjct: 465 ALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQ 496


>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
           sapiens]
          Length = 1259

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 14/32 (43%), Positives = 17/32 (53%)

Query: 10  AVPPPAGFTDSGRQSVSRAAGAAESEEDFLRQ 41
           A+PPP   T    Q     AG+  SE+D LRQ
Sbjct: 465 ALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQ 496


>gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo
           sapiens]
          Length = 1170

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 20/140 (14%)

Query: 158 EEVVAPLLRKVQCRDHEAVPLSVFRAGTLTCFVLLEFVARAGALFQLLEDSA-------- 209
           E+ VA  L K+   D  +V +S   +  + C  + +FVAR G  ++   +S+        
Sbjct: 437 EDSVAAHLSKILTSDQHSVVIS---SAKVLCETVKDFVARVGKAYEKTTESSEESEVMAK 493

Query: 210 -AAVADRRVGQAVLDTLEGALQASDA---AAPARFLEAGSRLGPDSLALAL-DRAVGGRR 264
             +V   ++  ++L TL+   QAS +     P    EA    G  S+  +  DR V    
Sbjct: 494 KCSVLKEKL-DSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASAC 552

Query: 265 PSAPM---TREEFLERAAAL 281
           P+ P     RE+ + RA +L
Sbjct: 553 PARPQIFRPREQLMLRANSL 572


>gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo
           sapiens]
          Length = 1214

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 20/140 (14%)

Query: 158 EEVVAPLLRKVQCRDHEAVPLSVFRAGTLTCFVLLEFVARAGALFQLLEDSA-------- 209
           E+ VA  L K+   D  +V +S   +  + C  + +FVAR G  ++   +S+        
Sbjct: 481 EDSVAAHLSKILTSDQHSVVIS---SAKVLCETVKDFVARVGKAYEKTTESSEESEVMAK 537

Query: 210 -AAVADRRVGQAVLDTLEGALQASDA---AAPARFLEAGSRLGPDSLALAL-DRAVGGRR 264
             +V   ++  ++L TL+   QAS +     P    EA    G  S+  +  DR V    
Sbjct: 538 KCSVLKEKL-DSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASAC 596

Query: 265 PSAPM---TREEFLERAAAL 281
           P+ P     RE+ + RA +L
Sbjct: 597 PARPQIFRPREQLMLRANSL 616


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 8/71 (11%)

Query: 203 QLLEDSAAAVADRRVGQAVLDTLEGALQASDAAAPARFLEAGSRLGPDSLALALDRAVGG 262
           Q LED  AA A  ++ QA  ++ E  LQA      A FL+        +L   L  A  G
Sbjct: 653 QKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQ--------TLKNPLPEAEAG 704

Query: 263 RRPSAPMTREE 273
           +   +P + EE
Sbjct: 705 KIEESPFSVEE 715


>gi|7662230 ring finger protein 40 [Homo sapiens]
          Length = 1001

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 28  AAGAAESEEDFLRQVGVTEMLRAALLKVLEA--RPEEPIAFLAHYFENMGLRSPVNGGAG 85
           A GA+ SEE  L   G  E  +AA+ +V+EA  R +  +  L     + G   P++  A 
Sbjct: 168 ALGASSSEEVELELQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQ 227

Query: 86  EPPGQLLLQQQRLGRALWHLRLAHH 110
               +L  + +RL      L+  HH
Sbjct: 228 AHTRELGRENRRLQDLATQLQEKHH 252


>gi|187608615 tyrosine kinase 2 [Homo sapiens]
          Length = 1187

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 14/42 (33%), Positives = 20/42 (47%)

Query: 122 VAYECLSAGGRRKRPGLDGRTYSELLRRICRDGQAPEEVVAP 163
           +A ECL  G       +D   +   L  IC DG+AP +  +P
Sbjct: 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,223,492
Number of Sequences: 37866
Number of extensions: 494369
Number of successful extensions: 1315
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1307
Number of HSP's gapped (non-prelim): 12
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.