Search of human proteins with 32698962

Search of human proteins with 32698962

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32698962 glycerophosphodiester phosphodiesterase domain
containing 1 [Homo sapiens]
         (314 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32698962 glycerophosphodiester phosphodiesterase domain conta...   634   0.0  
gi|146198640 glycerophosphodiester phosphodiesterase domain cont...   261   4e-70
gi|7706617 glycerophosphodiester phosphodiesterase 1 [Homo sapiens]    59   6e-09
gi|33457301 glycerophosphodiester phosphodiesterase domain conta...    48   1e-05
gi|21361649 osteoblast differentiation promoting factor protein ...    37   0.023
gi|25901062 hypothetical protein LOC56261 [Homo sapiens]               33   0.25 
gi|189571657 glycerophosphodiester phosphodiesterase domain cont...    32   0.73 
gi|17865816 vanin 2 isoform 2 [Homo sapiens]                           31   1.2  
gi|17865814 vanin 2 isoform 1 precursor [Homo sapiens]                 31   1.2  
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]     31   1.6  
gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]       30   2.8  
gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]       30   2.8  
gi|39930577 arylsulfatase K [Homo sapiens]                             29   6.2  
gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]          28   8.1  
gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]          28   8.1  

>gi|32698962 glycerophosphodiester phosphodiesterase domain
           containing 1 [Homo sapiens]
          Length = 314

 Score =  634 bits (1634), Expect = 0.0
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MSSTAAFYLLSTLGGYLVTSFLLLKYPTLLHQRKKQRFLSKHISHRGGAGENLENTMAAF 60
           MSSTAAFYLLSTLGGYLVTSFLLLKYPTLLHQRKKQRFLSKHISHRGGAGENLENTMAAF
Sbjct: 1   MSSTAAFYLLSTLGGYLVTSFLLLKYPTLLHQRKKQRFLSKHISHRGGAGENLENTMAAF 60

Query: 61  QHAVKIGTDTLELDCHITKDEQVVVSHDENLKRATGVNVNISDLKYCELPPYLGKLDVSF 120
           QHAVKIGTDTLELDCHITKDEQVVVSHDENLKRATGVNVNISDLKYCELPPYLGKLDVSF
Sbjct: 61  QHAVKIGTDTLELDCHITKDEQVVVSHDENLKRATGVNVNISDLKYCELPPYLGKLDVSF 120

Query: 121 QRACQCEGKDNRIPLLKEVFEAFPNTPINIDIKVNNNVLIKKVSELVKRYNREHLTVWGN 180
           QRACQCEGKDNRIPLLKEVFEAFPNTPINIDIKVNNNVLIKKVSELVKRYNREHLTVWGN
Sbjct: 121 QRACQCEGKDNRIPLLKEVFEAFPNTPINIDIKVNNNVLIKKVSELVKRYNREHLTVWGN 180

Query: 181 ANYEIVEKCYKENSDIPILFSLQRVLLILGLFFTGLLPFVPIREQFFEIPMPSIILKLKE 240
           ANYEIVEKCYKENSDIPILFSLQRVLLILGLFFTGLLPFVPIREQFFEIPMPSIILKLKE
Sbjct: 181 ANYEIVEKCYKENSDIPILFSLQRVLLILGLFFTGLLPFVPIREQFFEIPMPSIILKLKE 240

Query: 241 PHTMSRSQKFLIWLSDLLLMRKALFDHLTARGIQVYIWVLNEEQEYKRAFDLGATGVMTD 300
           PHTMSRSQKFLIWLSDLLLMRKALFDHLTARGIQVYIWVLNEEQEYKRAFDLGATGVMTD
Sbjct: 241 PHTMSRSQKFLIWLSDLLLMRKALFDHLTARGIQVYIWVLNEEQEYKRAFDLGATGVMTD 300

Query: 301 YPTKLRDFLHNFSA 314
           YPTKLRDFLHNFSA
Sbjct: 301 YPTKLRDFLHNFSA 314


>gi|146198640 glycerophosphodiester phosphodiesterase domain
           containing 3 [Homo sapiens]
          Length = 318

 Score =  261 bits (668), Expect = 4e-70
 Identities = 130/309 (42%), Positives = 197/309 (63%)

Query: 3   STAAFYLLSTLGGYLVTSFLLLKYPTLLHQRKKQRFLSKHISHRGGAGENLENTMAAFQH 62
           S   +Y L  LG Y + S   L+ P LLH  +   F  +  +HRGG+GE LENTM A ++
Sbjct: 2   SLLLYYALPALGSYAMLSIFFLRRPHLLHTPRAPTFRIRLGAHRGGSGELLENTMEAMEN 61

Query: 63  AVKIGTDTLELDCHITKDEQVVVSHDENLKRATGVNVNISDLKYCELPPYLGKLDVSFQR 122
           ++   +D LELDC +T+D  VVVSHDENL R +G+N ++  L + +LP Y  KL+V F  
Sbjct: 62  SMAQRSDLLELDCQLTRDRVVVVSHDENLCRQSGLNRDVGSLDFEDLPLYKEKLEVYFSP 121

Query: 123 ACQCEGKDNRIPLLKEVFEAFPNTPINIDIKVNNNVLIKKVSELVKRYNREHLTVWGNAN 182
                G D R+  L+++F+ FP TP++++IK  N  LI++++ LV+RY+R  +T+W +  
Sbjct: 122 GHFAHGSDRRMVRLEDLFQRFPRTPMSVEIKGKNEELIREIAGLVRRYDRNEITIWASEK 181

Query: 183 YEIVEKCYKENSDIPILFSLQRVLLILGLFFTGLLPFVPIREQFFEIPMPSIILKLKEPH 242
             +++KC   N ++P+ F++ R   +L  ++ GLLPF+PI E+FF   +P+II +   P 
Sbjct: 182 SSVMKKCKAANPEMPLSFTISRGFWVLLSYYLGLLPFIPIPEKFFFCFLPNIINRTYFPF 241

Query: 243 TMSRSQKFLIWLSDLLLMRKALFDHLTARGIQVYIWVLNEEQEYKRAFDLGATGVMTDYP 302
           + S   + L  +S  L+MRK+L  HL  RG+QV  W LNEE +++ AF +GATGV+TDYP
Sbjct: 242 SCSCLNQLLAVVSKWLIMRKSLIRHLEERGVQVVFWCLNEESDFEAAFSVGATGVITDYP 301

Query: 303 TKLRDFLHN 311
           T LR +L N
Sbjct: 302 TALRHYLDN 310


>gi|7706617 glycerophosphodiester phosphodiesterase 1 [Homo sapiens]
          Length = 331

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 63/253 (24%), Positives = 108/253 (42%), Gaps = 20/253 (7%)

Query: 43  ISHRGGAGENLENTMAAFQHAVKIGTDTLELDCHITKDEQVVVSHDENLKRATGVNVNIS 102
           I+HRGG+ +  ENT+AA + A K G   +ELD   T D   V+ HD  + R T     + 
Sbjct: 68  IAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTTDGTGRLC 127

Query: 103 DLKYCELPPYLGKLDVSFQRACQCEGKDNRIPLLKEVFEAFPNTPINIDIKVNNNVLIKK 162
           DL +      + KL+ +     + +  D +IP L+E      N  + I   V  +    K
Sbjct: 128 DLTF----EQIRKLNPAANHRLRNDFPDEKIPTLREAVAECLNHNLTIFFDVKGHA--HK 181

Query: 163 VSELVKRYNREHLTVWGNANY--EIVEKCYK-ENSDIPILFSLQRVLLILGLFFTGLLPF 219
            +E +K+   E   ++ N+     + E  YK   +D  ++ +L      L     G   +
Sbjct: 182 ATEALKKMYMEFPQLYNNSVVCSFLPEVIYKMRQTDRDVITALTHRPWSLSHTGDGKPRY 241

Query: 220 VPIREQFFEIPMPSIILKLKEPHTMSRSQKFLIWLSDLLLMR----KALFDHLTARGIQV 275
               + F  + M  ++       +M     +L  +S  L+ +     A     +A+GIQV
Sbjct: 242 DTFWKHFIFVMMDILL-----DWSMHNILWYLCGISAFLMQKDFVSPAYLKKWSAKGIQV 296

Query: 276 YIWVLN--EEQEY 286
             W +N  +E+ Y
Sbjct: 297 VGWTVNTFDEKSY 309


>gi|33457301 glycerophosphodiester phosphodiesterase domain
           containing 4 [Homo sapiens]
          Length = 520

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 4/105 (3%)

Query: 8   YLLSTLGGYLVTSFLLLKYPTLLHQRKKQRFLSKHISHRGGAGENLENTMAAFQHAVKIG 67
           +LL  LG YL+   +   Y   + +++          HRG      ENTM +F+ AV+ G
Sbjct: 169 FLLILLGLYLMPLGI---YSPCIQEKENLGPKPTIFGHRGAPMLGPENTMMSFEKAVEHG 225

Query: 68  TDTLELDCHITKDEQVVVSHDENLKRATGVNVNISDLKYCELPPY 112
              LE D H++ D    + HD +LKR T +   +     CE P +
Sbjct: 226 AHGLETDIHLSYDHVPFLMHDFDLKRTTNIG-EVQPESACENPAF 269


>gi|21361649 osteoblast differentiation promoting factor protein
           [Homo sapiens]
          Length = 539

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 33/133 (24%), Positives = 53/133 (39%), Gaps = 24/133 (18%)

Query: 43  ISHRGGAGENLENTMAAFQHAVKIGTDTLELDCHITKDEQVVVSHDENLKRATGV----- 97
           + HRG      ENT+ + +   + G    E D  ++ D    + HDE+L R T V     
Sbjct: 227 VGHRGAPMLAPENTLMSLRKTAECGATVFETDVMVSSDGVPFLMHDEHLSRTTNVASVFP 286

Query: 98  ---NVNISDLKYCELP------------PYLGKLDVSFQRACQCEGKDNRIPLLKEVFE- 141
                + SD  + EL             P+ G   ++     Q E +   +P L+E+ E 
Sbjct: 287 TRITAHSSDFSWTELKRLNAGSWFLERRPFWGAKPLA--GPDQKEAESQTVPALEELLEE 344

Query: 142 -AFPNTPINIDIK 153
            A  N  I  D++
Sbjct: 345 AAALNLSIMFDLR 357


>gi|25901062 hypothetical protein LOC56261 [Homo sapiens]
          Length = 672

 Score = 33.5 bits (75), Expect = 0.25
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 8/54 (14%)

Query: 43  ISHRGGAGENL--------ENTMAAFQHAVKIGTDTLELDCHITKDEQVVVSHD 88
           + HRG              ENT+A+ ++A   G   +E D H++KD   VV HD
Sbjct: 321 VGHRGAGNSTTTAQLAKVQENTIASLRNAASHGAAFVEFDVHLSKDFVPVVYHD 374


>gi|189571657 glycerophosphodiester phosphodiesterase domain
           containing 5 [Homo sapiens]
          Length = 605

 Score = 32.0 bits (71), Expect = 0.73
 Identities = 19/62 (30%), Positives = 30/62 (48%)

Query: 43  ISHRGGAGENLENTMAAFQHAVKIGTDTLELDCHITKDEQVVVSHDENLKRATGVNVNIS 102
           I HRG      E+T+ +F+ A++     L+ D  I+ D    + HD  L+R T V     
Sbjct: 231 IGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFP 290

Query: 103 DL 104
           +L
Sbjct: 291 EL 292


>gi|17865816 vanin 2 isoform 2 [Homo sapiens]
          Length = 467

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 10/88 (11%)

Query: 107 CELPPYLGKLDVSFQRACQCEGKDNRIPLLKEVFEAFP------NTPINIDIKVNNNVLI 160
           C+ P   G   V  Q    C  KDN I +L  + +  P        P N   + N NV+ 
Sbjct: 57  CQDPHRFGHTPV--QARLSCLAKDNSIYVLANLGDKKPCNSRDSTCPPNGYFQYNTNVVY 114

Query: 161 KKVSELVKRYNREHLTVWGNANYEIVEK 188
               +LV RY++ HL  +    + + EK
Sbjct: 115 NTEGKLVARYHKYHL--YSEPQFNVPEK 140


>gi|17865814 vanin 2 isoform 1 precursor [Homo sapiens]
          Length = 520

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 10/88 (11%)

Query: 107 CELPPYLGKLDVSFQRACQCEGKDNRIPLLKEVFEAFP------NTPINIDIKVNNNVLI 160
           C+ P   G   V  Q    C  KDN I +L  + +  P        P N   + N NV+ 
Sbjct: 110 CQDPHRFGHTPV--QARLSCLAKDNSIYVLANLGDKKPCNSRDSTCPPNGYFQYNTNVVY 167

Query: 161 KKVSELVKRYNREHLTVWGNANYEIVEK 188
               +LV RY++ HL  +    + + EK
Sbjct: 168 NTEGKLVARYHKYHL--YSEPQFNVPEK 193


>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
          Length = 467

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 6/90 (6%)

Query: 111 PYLGKLDVSFQRACQCEGKDNRIPLLKEVFEAFPNTPIN---IDIKVNNNVLIKKVSELV 167
           P+L  L V   +A     K+     +++  E F   P N      K   NV+++K+ E+ 
Sbjct: 8   PFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQ 67

Query: 168 KRYNREHLTVWGNANYEIVEKCYKENSDIP 197
           + +    L V G  N E ++   K    +P
Sbjct: 68  RFFG---LNVTGKPNEETLDMMKKPRCGVP 94


>gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]
          Length = 929

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 9/124 (7%)

Query: 97  VNVNISDLKY----CELPPYLGKLDVSFQRACQCEGKDNRIPLLKEVFEAFPNTPINIDI 152
           +++N SD+K     C+   +LGKLD +F+   +C   + R    +E+     NT I   +
Sbjct: 70  IDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRL-NTSIQEKL 128

Query: 153 KV--NNNVLIKKVSELVKRYNREHLTVWGNANYEIVEKCYKENSDIPILFSLQRVLLILG 210
           +V  + +  ++K+ E++   N E       AN  IV    +E +    +F    V L+L 
Sbjct: 129 RVQFSTDSRVQKMFEILLDENSEADKREKAANNLIV--LGREEAGAEKIFQNNGVALLLQ 186

Query: 211 LFFT 214
           L  T
Sbjct: 187 LLDT 190


>gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]
          Length = 931

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 9/124 (7%)

Query: 97  VNVNISDLKY----CELPPYLGKLDVSFQRACQCEGKDNRIPLLKEVFEAFPNTPINIDI 152
           +++N SD+K     C+   +LGKLD +F+   +C   + R    +E+     NT I   +
Sbjct: 70  IDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRL-NTSIQEKL 128

Query: 153 KV--NNNVLIKKVSELVKRYNREHLTVWGNANYEIVEKCYKENSDIPILFSLQRVLLILG 210
           +V  + +  ++K+ E++   N E       AN  IV    +E +    +F    V L+L 
Sbjct: 129 RVQFSTDSRVQKMFEILLDENSEADKREKAANNLIV--LGREEAGAEKIFQNNGVALLLQ 186

Query: 211 LFFT 214
           L  T
Sbjct: 187 LLDT 190


>gi|39930577 arylsulfatase K [Homo sapiens]
          Length = 536

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 14/43 (32%), Positives = 22/43 (51%)

Query: 136 LKEVFEAFPNTPINIDIKVNNNVLIKKVSELVKRYNREHLTVW 178
           L  V   FP    ++D K+++ +   KVS  V +YN+E    W
Sbjct: 449 LTNVAVKFPEITYSLDQKLHSIINYPKVSASVHQYNKEQFIKW 491


>gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]
          Length = 1291

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 14/52 (26%), Positives = 26/52 (50%)

Query: 40  SKHISHRGGAGENLENTMAAFQHAVKIGTDTLELDCHITKDEQVVVSHDENL 91
           S H ++  G   + E+++ A+   +++G   +ELDC    D   V+ H   L
Sbjct: 333 SSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTL 384


>gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]
          Length = 1290

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 14/52 (26%), Positives = 26/52 (50%)

Query: 40  SKHISHRGGAGENLENTMAAFQHAVKIGTDTLELDCHITKDEQVVVSHDENL 91
           S H ++  G   + E+++ A+   +++G   +ELDC    D   V+ H   L
Sbjct: 333 SSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTL 384


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,225,116
Number of Sequences: 37866
Number of extensions: 468044
Number of successful extensions: 872
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 862
Number of HSP's gapped (non-prelim): 15
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.