Guide to the Human Genome
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Search of human proteins with 32455266

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32455266 peroxiredoxin 1 [Homo sapiens]
         (199 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32455266 peroxiredoxin 1 [Homo sapiens]                            412   e-115
gi|32455264 peroxiredoxin 1 [Homo sapiens]                            412   e-115
gi|4505591 peroxiredoxin 1 [Homo sapiens]                             412   e-115
gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]                  332   2e-91
gi|5453549 peroxiredoxin 4 [Homo sapiens]                             287   5e-78
gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]         264   3e-71
gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]                  264   3e-71
gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo ...   193   7e-50
gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]                  145   2e-35
gi|4758638 peroxiredoxin 6 [Homo sapiens]                              80   1e-15
gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]      35   0.055
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]                   30   1.8  
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi...    28   6.7  
gi|186928819 hepatoma-derived growth factor isoform b [Homo sapi...    28   6.7  
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]     28   6.7  
gi|75832029 connexin 43-interacting protein 150 isoform a [Homo ...    28   6.7  

>gi|32455266 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  412 bits (1059), Expect = e-115
 Identities = 199/199 (100%), Positives = 199/199 (100%)

Query: 1   MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60
           MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
Sbjct: 1   MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60

Query: 61  DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK 120
           DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
Sbjct: 61  DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK 120

Query: 121 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG 180
           ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
Sbjct: 121 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG 180

Query: 181 SDTIKPDVQKSKEYFSKQK 199
           SDTIKPDVQKSKEYFSKQK
Sbjct: 181 SDTIKPDVQKSKEYFSKQK 199


>gi|32455264 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  412 bits (1059), Expect = e-115
 Identities = 199/199 (100%), Positives = 199/199 (100%)

Query: 1   MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60
           MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
Sbjct: 1   MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60

Query: 61  DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK 120
           DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
Sbjct: 61  DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK 120

Query: 121 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG 180
           ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
Sbjct: 121 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG 180

Query: 181 SDTIKPDVQKSKEYFSKQK 199
           SDTIKPDVQKSKEYFSKQK
Sbjct: 181 SDTIKPDVQKSKEYFSKQK 199


>gi|4505591 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  412 bits (1059), Expect = e-115
 Identities = 199/199 (100%), Positives = 199/199 (100%)

Query: 1   MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60
           MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
Sbjct: 1   MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60

Query: 61  DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK 120
           DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
Sbjct: 61  DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK 120

Query: 121 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG 180
           ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
Sbjct: 121 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG 180

Query: 181 SDTIKPDVQKSKEYFSKQK 199
           SDTIKPDVQKSKEYFSKQK
Sbjct: 181 SDTIKPDVQKSKEYFSKQK 199


>gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]
          Length = 198

 Score =  332 bits (850), Expect = 2e-91
 Identities = 154/197 (78%), Positives = 180/197 (91%), Gaps = 1/197 (0%)

Query: 1   MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60
           M+SGNA+IG PAP+FKATAV+ DG FK++ LSDYKGKYVV FFYPLDFTFVCPTEIIAFS
Sbjct: 1   MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS 59

Query: 61  DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK 120
           +RAE+F+KL C+V+G SVDS F HLAW+NTP+K+GGLGP+NIPL++D  R +++DYGVLK
Sbjct: 60  NRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLK 119

Query: 121 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG 180
            DEGI++RGLFIID KG+LRQITVNDLPVGRSVDE LRLVQAFQ+TD+HGEVCPAGWKPG
Sbjct: 120 TDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPG 179

Query: 181 SDTIKPDVQKSKEYFSK 197
           SDTIKP+V  SKEYFSK
Sbjct: 180 SDTIKPNVDDSKEYFSK 196


>gi|5453549 peroxiredoxin 4 [Homo sapiens]
          Length = 271

 Score =  287 bits (734), Expect = 5e-78
 Identities = 135/192 (70%), Positives = 160/192 (83%), Gaps = 1/192 (0%)

Query: 6   AKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEE 65
           AKI  PAP ++ TAV+ DG+FK++ L+DY+GKY+VFFFYPLDFTFVCPTEIIAF DR EE
Sbjct: 79  AKISKPAPYWEGTAVI-DGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEE 137

Query: 66  FKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGI 125
           F+ +N +V+  SVDS F HLAW+NTP++QGGLGP+ IPL+SD    I++DYGV   D G 
Sbjct: 138 FRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLTHQISKDYGVYLEDSGH 197

Query: 126 SFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIK 185
           + RGLFIIDDKGILRQIT+NDLPVGRSVDETLRLVQAFQ+TDKHGEVCPAGWKPGS+TI 
Sbjct: 198 TLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETII 257

Query: 186 PDVQKSKEYFSK 197
           PD     +YF K
Sbjct: 258 PDPAGKLKYFDK 269


>gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]
          Length = 256

 Score =  264 bits (675), Expect = 3e-71
 Identities = 122/186 (65%), Positives = 150/186 (80%), Gaps = 1/186 (0%)

Query: 12  APNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNC 71
           AP FK TAV+ +G+FKD+SL D+KGKY+V FFYPLDFTFVCPTEI+AFSD+A EF  +NC
Sbjct: 69  APYFKGTAVV-NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNC 127

Query: 72  QVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLF 131
           +V+  SVDSHF HLAW+NTP+K GGLG MNI L+SD  + I++DYGVL    G++ RGLF
Sbjct: 128 EVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLF 187

Query: 132 IIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKS 191
           IID  G+++ ++VNDLPVGRSV+ETLRLV+AFQ+ + HGEVCPA W P S TIKP    S
Sbjct: 188 IIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAAS 247

Query: 192 KEYFSK 197
           KEYF K
Sbjct: 248 KEYFQK 253


>gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]
          Length = 238

 Score =  264 bits (675), Expect = 3e-71
 Identities = 122/186 (65%), Positives = 150/186 (80%), Gaps = 1/186 (0%)

Query: 12  APNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNC 71
           AP FK TAV+ +G+FKD+SL D+KGKY+V FFYPLDFTFVCPTEI+AFSD+A EF  +NC
Sbjct: 51  APYFKGTAVV-NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNC 109

Query: 72  QVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLF 131
           +V+  SVDSHF HLAW+NTP+K GGLG MNI L+SD  + I++DYGVL    G++ RGLF
Sbjct: 110 EVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLF 169

Query: 132 IIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKS 191
           IID  G+++ ++VNDLPVGRSV+ETLRLV+AFQ+ + HGEVCPA W P S TIKP    S
Sbjct: 170 IIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAAS 229

Query: 192 KEYFSK 197
           KEYF K
Sbjct: 230 KEYFQK 235


>gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo
           sapiens]
          Length = 233

 Score =  193 bits (491), Expect = 7e-50
 Identities = 101/174 (58%), Positives = 122/174 (70%), Gaps = 25/174 (14%)

Query: 6   AKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEE 65
           AKI  PAP ++ TAV+ DG+FK++ L+DY+GKY+VFFFYPLDFTFVCPTEIIAF DR EE
Sbjct: 79  AKISKPAPYWEGTAVI-DGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEE 137

Query: 66  FKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGI 125
           F+ +N +V+  SVDS F HLAW                       +++  Y   K    +
Sbjct: 138 FRSINTEVVACSVDSQFTHLAW-----------------------SVSYTYIRRKKRMDL 174

Query: 126 SFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCP-AGWK 178
             +GLFIIDDKGILRQIT+NDLPVGRSVDETLRLVQAFQ+TDKHGE  P + WK
Sbjct: 175 LLKGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWK 228


>gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]
          Length = 142

 Score =  145 bits (366), Expect = 2e-35
 Identities = 69/95 (72%), Positives = 82/95 (86%), Gaps = 2/95 (2%)

Query: 1  MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60
          M+SGNA+IG PAP+FKATAV+ DG FK++ LSDYKGKYVV FFYPLDFTFVCPTEIIAFS
Sbjct: 1  MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS 59

Query: 61 DRAEEFKKLNCQVIGASVDSHFCHLAWVNT-PKKQ 94
          +RAE+F+KL C+V+G SVDS F HLAW    PK++
Sbjct: 60 NRAEDFRKLGCEVLGVSVDSQFTHLAWYEQGPKRE 94


>gi|4758638 peroxiredoxin 6 [Homo sapiens]
          Length = 224

 Score = 79.7 bits (195), Expect = 1e-15
 Identities = 64/206 (31%), Positives = 100/206 (48%), Gaps = 16/206 (7%)

Query: 4   GNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRA 63
           G   +G  APNF+A   +   +F D  L D  G   + F +P DFT VC TE+   +  A
Sbjct: 3   GGLLLGDVAPNFEANTTVGRIRFHDF-LGDSWG---ILFSHPRDFTPVCTTELGRAAKLA 58

Query: 64  EEFKKLNCQVIGASVDSHFCHLAW---VNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVL- 119
            EF K N ++I  S+DS   HLAW   +N    +     +  P++ D  R +A   G+L 
Sbjct: 59  PEFAKRNVKLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLD 118

Query: 120 ---KADEG--ISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCP 174
              K ++G  ++ R +F+      L+   +     GR+ DE LR+V + Q T +     P
Sbjct: 119 PAEKDEKGMPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATP 178

Query: 175 AGWKPG-SDTIKPDV--QKSKEYFSK 197
             WK G S  + P +  +++K+ F K
Sbjct: 179 VDWKDGDSVMVLPTIPEEEAKKLFPK 204


>gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]
          Length = 137

 Score = 34.7 bits (78), Expect = 0.055
 Identities = 18/48 (37%), Positives = 25/48 (52%)

Query: 40 VFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAW 87
          + F +P D   VC  E+   +  A EF K N ++I  + DS   HLAW
Sbjct: 34 ILFSHPRDSKPVCTMELGRAAKLAPEFTKSNVKLIALATDSAEDHLAW 81


>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
          Length = 384

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 13/28 (46%), Positives = 18/28 (64%)

Query: 20  VMPDGQFKDISLSDYKGKYVVFFFYPLD 47
           VM D  F++++L  YK KYV F  +P D
Sbjct: 178 VMTDEPFQNVTLDAYKDKYVCFDQFPSD 205


>gi|186928821 hepatoma-derived growth factor isoform c [Homo
          sapiens]
          Length = 233

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 12/46 (26%), Positives = 23/46 (50%)

Query: 25 QFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLN 70
          +  + ++     KY VFFF   +  F+ P ++  + +  E+F K N
Sbjct: 25 EMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPN 70


>gi|186928819 hepatoma-derived growth factor isoform b [Homo
          sapiens]
          Length = 256

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 12/46 (26%), Positives = 23/46 (50%)

Query: 25 QFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLN 70
          +  + ++     KY VFFF   +  F+ P ++  + +  E+F K N
Sbjct: 48 EMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPN 93


>gi|4758516 hepatoma-derived growth factor isoform a [Homo
          sapiens]
          Length = 240

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 12/46 (26%), Positives = 23/46 (50%)

Query: 25 QFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLN 70
          +  + ++     KY VFFF   +  F+ P ++  + +  E+F K N
Sbjct: 32 EMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPN 77


>gi|75832029 connexin 43-interacting protein 150 isoform a [Homo
            sapiens]
          Length = 1344

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 6/75 (8%)

Query: 124  GISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDT 183
            G+  R   II+   ++ Q +  D  + +++   L  V  +  TD     CP G+KP  + 
Sbjct: 1205 GLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDRWASTD-----CP-GYKPFLNI 1258

Query: 184  IKPDVQKSKEYFSKQ 198
            IKP +QK  E   +Q
Sbjct: 1259 IKPQLQKLSEITEEQ 1273


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,824,336
Number of Sequences: 37866
Number of extensions: 329688
Number of successful extensions: 505
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 483
Number of HSP's gapped (non-prelim): 16
length of query: 199
length of database: 18,247,518
effective HSP length: 97
effective length of query: 102
effective length of database: 14,574,516
effective search space: 1486600632
effective search space used: 1486600632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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