Guide to the Human Genome
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Search of human proteins with 30065649

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30065649 protein phosphatase 2A, regulatory subunit B'
isoform d [Homo sapiens]
         (281 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30065649 protein phosphatase 2A, regulatory subunit B' isofor...   580   e-166
gi|30065643 protein phosphatase 2A, regulatory subunit B' isofor...   560   e-160
gi|29725611 protein phosphatase 2A, regulatory subunit B' isofor...   560   e-160
gi|30065645 protein phosphatase 2A, regulatory subunit B' isofor...   437   e-123
gi|30410794 proteasome activator subunit 3 isoform 1 [Homo sapiens]    30   2.4  
gi|30410796 proteasome activator subunit 3 isoform 2 [Homo sapiens]    30   2.4  
gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens]    29   4.0  
gi|6912464 latrophilin 2 precursor [Homo sapiens]                      29   5.3  
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H...    28   9.0  
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H...    28   9.0  
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho...    28   9.0  
gi|7108333 apoptotic peptidase activating factor 1 isoform a [Ho...    28   9.0  
gi|8923920 H2A histone family, member Y2 [Homo sapiens]                28   9.0  

>gi|30065649 protein phosphatase 2A, regulatory subunit B' isoform d
           [Homo sapiens]
          Length = 281

 Score =  580 bits (1496), Expect = e-166
 Identities = 281/281 (100%), Positives = 281/281 (100%)

Query: 1   MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK 60
           MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK
Sbjct: 1   MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK 60

Query: 61  GKKLTFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAF 120
           GKKLTFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAF
Sbjct: 61  GKKLTFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAF 120

Query: 121 LCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIW 180
           LCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIW
Sbjct: 121 LCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIW 180

Query: 181 GSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVP 240
           GSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVP
Sbjct: 181 GSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVP 240

Query: 241 SWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG 281
           SWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG
Sbjct: 241 SWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG 281


>gi|30065643 protein phosphatase 2A, regulatory subunit B' isoform b
           [Homo sapiens]
          Length = 323

 Score =  560 bits (1443), Expect = e-160
 Identities = 281/323 (86%), Positives = 281/323 (86%), Gaps = 42/323 (13%)

Query: 1   MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK 60
           MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK
Sbjct: 1   MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK 60

Query: 61  GKKLTFEYRVSE------------------------------------------EAENLV 78
           GKKLTFEYRVSE                                          EAENLV
Sbjct: 61  GKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLV 120

Query: 79  ATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAI 138
           ATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAI
Sbjct: 121 ATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAI 180

Query: 139 VFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVD 198
           VFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVD
Sbjct: 181 VFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVD 240

Query: 199 EKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECL 258
           EKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECL
Sbjct: 241 EKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECL 300

Query: 259 EKFPVIQHFKFGSLLPIHPVTSG 281
           EKFPVIQHFKFGSLLPIHPVTSG
Sbjct: 301 EKFPVIQHFKFGSLLPIHPVTSG 323


>gi|29725611 protein phosphatase 2A, regulatory subunit B' isoform b
           [Homo sapiens]
          Length = 323

 Score =  560 bits (1443), Expect = e-160
 Identities = 281/323 (86%), Positives = 281/323 (86%), Gaps = 42/323 (13%)

Query: 1   MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK 60
           MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK
Sbjct: 1   MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK 60

Query: 61  GKKLTFEYRVSE------------------------------------------EAENLV 78
           GKKLTFEYRVSE                                          EAENLV
Sbjct: 61  GKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLV 120

Query: 79  ATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAI 138
           ATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAI
Sbjct: 121 ATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAI 180

Query: 139 VFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVD 198
           VFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVD
Sbjct: 181 VFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVD 240

Query: 199 EKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECL 258
           EKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECL
Sbjct: 241 EKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECL 300

Query: 259 EKFPVIQHFKFGSLLPIHPVTSG 281
           EKFPVIQHFKFGSLLPIHPVTSG
Sbjct: 301 EKFPVIQHFKFGSLLPIHPVTSG 323


>gi|30065645 protein phosphatase 2A, regulatory subunit B' isoform a
           [Homo sapiens]
          Length = 358

 Score =  437 bits (1124), Expect = e-123
 Identities = 211/217 (97%), Positives = 214/217 (98%)

Query: 65  TFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCL 124
           T+  ++ EEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCL
Sbjct: 142 TWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCL 201

Query: 125 CKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQ 184
           CKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQ
Sbjct: 202 CKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQ 261

Query: 185 LIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSK 244
           LIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSK
Sbjct: 262 LIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSK 321

Query: 245 VNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG 281
           VNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG
Sbjct: 322 VNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG 358



 Score =  151 bits (382), Expect = 5e-37
 Identities = 72/72 (100%), Positives = 72/72 (100%)

Query: 1  MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK 60
          MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK
Sbjct: 1  MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK 60

Query: 61 GKKLTFEYRVSE 72
          GKKLTFEYRVSE
Sbjct: 61 GKKLTFEYRVSE 72


>gi|30410794 proteasome activator subunit 3 isoform 1 [Homo sapiens]
          Length = 254

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 4/52 (7%)

Query: 52  ILTLNEGVKGKKLTFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGN 103
           +L +++ VK K  +F  R++ EAE+LVA   P  L     E+  +LKE + N
Sbjct: 4   LLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLL----ELDSFLKEPILN 51


>gi|30410796 proteasome activator subunit 3 isoform 2 [Homo sapiens]
          Length = 267

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 4/52 (7%)

Query: 52  ILTLNEGVKGKKLTFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGN 103
           +L +++ VK K  +F  R++ EAE+LVA   P  L     E+  +LKE + N
Sbjct: 4   LLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLL----ELDSFLKEPILN 51


>gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens]
          Length = 487

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 6/70 (8%)

Query: 13  SEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFE----Y 68
           S  +PP+TQ F++P+         G  K  Q        I +L   ++  +  FE    Y
Sbjct: 256 SAPSPPSTQQFMMPRSSSRC--SCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313

Query: 69  RVSEEAENLV 78
           RV+++ +NL+
Sbjct: 314 RVTKQDKNLI 323


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 1/43 (2%)

Query: 2   AEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMG-KWKRSQ 43
           ++G + PP  S+ + PP T  F +P++    +   G KW ++Q
Sbjct: 441 SKGTKPPPAVSTTKIPPITNIFPLPERFCEALDSKGIKWPQTQ 483


>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
           sapiens]
          Length = 1205

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 15/34 (44%), Positives = 24/34 (70%), Gaps = 3/34 (8%)

Query: 181 GSSQLIDHPYLEPRHFVDEK--AVNENHKDYMFL 212
           G + LI H ++E RH +DEK  AV+EN ++++ L
Sbjct: 518 GPAHLI-HEFVEYRHILDEKDCAVSENFQEFLSL 550


>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
           sapiens]
          Length = 1248

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 15/34 (44%), Positives = 24/34 (70%), Gaps = 3/34 (8%)

Query: 181 GSSQLIDHPYLEPRHFVDEK--AVNENHKDYMFL 212
           G + LI H ++E RH +DEK  AV+EN ++++ L
Sbjct: 518 GPAHLI-HEFVEYRHILDEKDCAVSENFQEFLSL 550


>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
           sapiens]
          Length = 1194

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 15/34 (44%), Positives = 24/34 (70%), Gaps = 3/34 (8%)

Query: 181 GSSQLIDHPYLEPRHFVDEK--AVNENHKDYMFL 212
           G + LI H ++E RH +DEK  AV+EN ++++ L
Sbjct: 507 GPAHLI-HEFVEYRHILDEKDCAVSENFQEFLSL 539


>gi|7108333 apoptotic peptidase activating factor 1 isoform a [Homo
           sapiens]
          Length = 1237

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 15/34 (44%), Positives = 24/34 (70%), Gaps = 3/34 (8%)

Query: 181 GSSQLIDHPYLEPRHFVDEK--AVNENHKDYMFL 212
           G + LI H ++E RH +DEK  AV+EN ++++ L
Sbjct: 507 GPAHLI-HEFVEYRHILDEKDCAVSENFQEFLSL 539


>gi|8923920 H2A histone family, member Y2 [Homo sapiens]
          Length = 372

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 8/45 (17%)

Query: 62  KKLTFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTR 106
           KK TF+YR+S  A        P ++AA +  +A  + E  GN+ R
Sbjct: 33  KKGTFKYRISVGA--------PVYMAAVIEYLAAEILELAGNAAR 69


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,363,275
Number of Sequences: 37866
Number of extensions: 482760
Number of successful extensions: 1248
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1241
Number of HSP's gapped (non-prelim): 16
length of query: 281
length of database: 18,247,518
effective HSP length: 101
effective length of query: 180
effective length of database: 14,423,052
effective search space: 2596149360
effective search space used: 2596149360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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