Search of human proteins with 28416935

Search of human proteins with 28416935

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]
         (397 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]         815   0.0  
gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]         795   0.0  
gi|28416927 purinergic receptor P2X4 [Homo sapiens]                   333   2e-91
gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]         303   1e-82
gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]        290   1e-78
gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]          280   2e-75
gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]         269   4e-72
gi|28416925 purinergic receptor P2X3 [Homo sapiens]                   268   8e-72
gi|4505545 purinergic receptor P2X1 [Homo sapiens]                    267   1e-71
gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]         267   1e-71
gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]         259   4e-69
gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]        253   3e-67
gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]         205   5e-53
gi|29294631 purinergic receptor P2X7 [Homo sapiens]                   188   6e-48
gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]         187   1e-47
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]               32   1.0  
gi|167466187 integrin-binding sialoprotein precursor [Homo sapiens]    30   5.0  
gi|239757474 PREDICTED: similar to hCG1785205 [Homo sapiens]           30   5.0  
gi|239751984 PREDICTED: similar to hCG1785205 [Homo sapiens]           30   5.0  
gi|239746471 PREDICTED: hypothetical protein XP_002343764 [Homo ...    30   5.0  
gi|116089333 kelch domain containing 7A [Homo sapiens]                 30   5.0  
gi|170763517 transforming, acidic coiled-coil containing protein...    29   6.5  
gi|4758416 golgi-specific brefeldin A resistant guanine nucleoti...    29   6.5  
gi|166795264 AE binding protein 2 isoform b [Homo sapiens]             29   6.5  
gi|166795262 AE binding protein 2 isoform a [Homo sapiens]             29   6.5  
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]           29   8.5  
gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]              29   8.5  
gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]               29   8.5  
gi|33859793 hypothetical protein LOC139212 [Homo sapiens]              29   8.5  

>gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]
          Length = 397

 Score =  815 bits (2106), Expect = 0.0
 Identities = 397/397 (100%), Positives = 397/397 (100%)

Query: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60
           MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
Sbjct: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60

Query: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQNEGIPDGACSKDSDCHAGEAVTAG 120
           SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQNEGIPDGACSKDSDCHAGEAVTAG
Sbjct: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQNEGIPDGACSKDSDCHAGEAVTAG 120

Query: 121 NGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFS 180
           NGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFS
Sbjct: 121 NGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFS 180

Query: 181 NNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDL 240
           NNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDL
Sbjct: 181 NNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDL 240

Query: 241 DKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVN 300
           DKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVN
Sbjct: 241 DKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVN 300

Query: 301 GKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLG 360
           GKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLG
Sbjct: 301 GKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLG 360

Query: 361 MPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHRST 397
           MPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHRST
Sbjct: 361 MPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHRST 397


>gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]
          Length = 422

 Score =  795 bits (2054), Expect = 0.0
 Identities = 396/422 (93%), Positives = 397/422 (94%), Gaps = 25/422 (5%)

Query: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60
           MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
Sbjct: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60

Query: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQ------------------------ 96
           SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQ                        
Sbjct: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE 120

Query: 97  NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP 156
           NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
Sbjct: 121 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP 180

Query: 157 FLKEAEDFTIFIKNHIRFPKFNFS-NNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW 215
           FLKEAEDFTIFIKNHIRFPKFNFS +NVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
Sbjct: 181 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW 240

Query: 216 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY 275
           AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
Sbjct: 241 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY 300

Query: 276 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 335
           YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
Sbjct: 301 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 360

Query: 336 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 395
           SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
Sbjct: 361 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 420

Query: 396 ST 397
           ST
Sbjct: 421 ST 422


>gi|28416927 purinergic receptor P2X4 [Homo sapiens]
          Length = 388

 Score =  333 bits (854), Expect = 2e-91
 Identities = 181/386 (46%), Positives = 240/386 (62%), Gaps = 51/386 (13%)

Query: 6   CKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSA 65
           C  L   LF+Y T + V+ +++KVGL+ R +Q  ILAY++ WVF+ +KGYQ+ D S+ S+
Sbjct: 5   CAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETD-SVVSS 63

Query: 66  VITKVKGVAFTNTSDLGQRIWDVADYVIPAQNEG---------------------IPDGA 104
           V TKVKGVA TNTS LG RIWDVADYVIPAQ E                      IPD  
Sbjct: 64  VTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIPDAT 123

Query: 105 --CSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSR-PEEPFLKEA 161
             C  D+ C AG A T  NGV TGRC+      + TCE+ AWCP+E  +  P+  FLK A
Sbjct: 124 TVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVK-TCEVAAWCPVEDDTHVPQPAFLKAA 182

Query: 162 EDFTIFIKNHIRFPKFNFSN-NVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSD 219
           E+FT+ +KN+I +PKFNFS  N++     ++LKSC +  K   +CPIFRLG ++  AG  
Sbjct: 183 ENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAGHS 242

Query: 220 FQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNK-LSKSVSSGYNFRFARYYRD 278
           FQD+A+EGG++GI + W+C+LD+AAS C P YSF RLD + +  +VS GYNFRFA+YYRD
Sbjct: 243 FQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYYRD 302

Query: 279 AAGVEFRTLMKAYGIRFDVMVNGKGAFF----------------------CDLVLIYLIK 316
            AG E RTL+KAYGIRFD++V GK   F                      CD++++Y +K
Sbjct: 303 LAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYCMK 362

Query: 317 KREFYRDKKYEEVRGLEDSSQEAEDE 342
           KR +YR+KKY+ V   E       D+
Sbjct: 363 KRLYYREKKYKYVEDYEQGLASELDQ 388


>gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]
          Length = 178

 Score =  303 bits (777), Expect = 1e-82
 Identities = 154/178 (86%), Positives = 154/178 (86%), Gaps = 24/178 (13%)

Query: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60
           MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
Sbjct: 1   MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 60

Query: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQ------------------------ 96
           SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQ                        
Sbjct: 61  SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE 120

Query: 97  NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPE 154
           NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPE
Sbjct: 121 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPE 178


>gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]
          Length = 441

 Score =  290 bits (743), Expect = 1e-78
 Identities = 155/366 (42%), Positives = 212/366 (57%), Gaps = 57/366 (15%)

Query: 13  LFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVITKVKG 72
           L DYKTEKYV+ +N +VG L RLLQ  I+ Y+V W  L KKGYQ+ D   Q ++ITK+KG
Sbjct: 22  LLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLAKKGYQERDLEPQFSIITKLKG 81

Query: 73  VAFTNTSDLGQRIWDVADYVIPAQNE------------------------GIPDGACSKD 108
           V+ T   +LG R+WDVAD+V P Q E                         +P   C  D
Sbjct: 82  VSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWVD 141

Query: 109 SDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFI 168
            DC  GE  T  +GVKTG+C+      R TCEI++WCP+E+   P  P L +A++FT+FI
Sbjct: 142 EDCPEGEGGTHSHGVKTGQCVVFNGTHR-TCEIWSWCPVESGVVPSRPLLAQAQNFTLFI 200

Query: 169 KNHIRFPKFNFS-NNVMDVKDRSFLKSCHFGPK-NHYCPIFRLGSVIRWAGSDFQDIALE 226
           KN + F KFNFS +N ++  D ++ K C + P+ + YCP+FR+G ++  AG  F+D+AL 
Sbjct: 201 KNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKAGGTFEDLALL 260

Query: 227 GGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRT 286
           GG +GI + W+CDLD   S C PHYSF +L  K        YNFR A ++ +  GVE RT
Sbjct: 261 GGSVGIRVHWDCDLDTGDSGCWPHYSF-QLQEK-------SYNFRTATHWWEQPGVEART 312

Query: 287 LMKAYGIRFDVMVNGKG----------------------AFFCDLVLIYLIKKREFYRDK 324
           L+K YGIRFD++V G+                        FFCDL+L+Y+ ++  FY   
Sbjct: 313 LLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLLLLYVDREAHFYWRT 372

Query: 325 KYEEVR 330
           KYEE +
Sbjct: 373 KYEEAK 378


>gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]
          Length = 447

 Score =  280 bits (716), Expect = 2e-75
 Identities = 156/412 (37%), Positives = 232/412 (56%), Gaps = 40/412 (9%)

Query: 7   KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
           +G   +L+DY+T K ++ +N+++G+LYR +Q  IL Y V +VF+++K YQ+ +T  +S++
Sbjct: 19  RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78

Query: 67  ITKVKGVAFTNTSDLGQRIWDVADYVIPAQNEGIPDGACSKDSDCHAGEAVTAGNGVKTG 126
           ITKVKG+    TS+   ++WDV +YV P ++  + +  C  D+DC AGE    GNG++TG
Sbjct: 79  ITKVKGIT---TSE--HKVWDVEEYVKPPESIRVHNATCLSDADCVAGELDMLGNGLRTG 133

Query: 127 RCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSNNVMDV 186
           RC+        TCE+F WCP+E  +   +     A +FTI IKN I +PKF+FS   +  
Sbjct: 134 RCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIAD 193

Query: 187 KDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAAS 245
           +   +LK C F   +  YCPIF+LG ++  AG  F ++A +GGVIG+ I W+CDLD  AS
Sbjct: 194 RTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPAS 253

Query: 246 ECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK--- 302
           EC+P YSF RLD K     SSGYNFRFA+YY+   G   RTL+KAYGIR DV+V+G+   
Sbjct: 254 ECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-INGTTTRTLIKAYGIRIDVIVHGQAGK 311

Query: 303 -------------------GAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEA 343
                              G+F CD +L+  + K + Y  KK+++V      +      +
Sbjct: 312 FSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKV-----CTPSHPSGS 366

Query: 344 SGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 395
             + L+  L   P   G   + +   PP  + G       G+ C     P R
Sbjct: 367 WPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ-----QGAECGPAFPPLR 413


>gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]
          Length = 471

 Score =  269 bits (687), Expect = 4e-72
 Identities = 158/436 (36%), Positives = 234/436 (53%), Gaps = 64/436 (14%)

Query: 7   KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
           +G   +L+DY+T K ++ +N+++G+LYR +Q  IL Y V +VF+++K YQ+ +T  +S++
Sbjct: 19  RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78

Query: 67  ITKVKGVAFTNTSDLGQRIWDVADYVIP-----------------AQNEG-------IPD 102
           ITKVKG+    TS+   ++WDV +YV P                 +Q +G       + +
Sbjct: 79  ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133

Query: 103 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 162
             C  D+DC AGE    GNG++TGRC+        TCE+F WCP+E  +   +     A 
Sbjct: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 193

Query: 163 DFTIFIKNHIRFPKFNFSNNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQ 221
           +FTI IKN I +PKF+FS   +  +   +LK C F   +  YCPIF+LG ++  AG  F 
Sbjct: 194 NFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFT 253

Query: 222 DIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAG 281
           ++A +GGVIG+ I W+CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   G
Sbjct: 254 ELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-ING 311

Query: 282 VEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIKKRE 319
              RTL+KAYGIR DV+V+G+                      G+F CD +L+  + K +
Sbjct: 312 TTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNK 371

Query: 320 FYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSS 379
            Y  KK+++V      +      +  + L+  L   P   G   + +   PP  + G   
Sbjct: 372 VYSHKKFDKV-----CTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ-- 424

Query: 380 QKGNGSVCPQLLEPHR 395
               G+ C     P R
Sbjct: 425 ---QGAECGPAFPPLR 437


>gi|28416925 purinergic receptor P2X3 [Homo sapiens]
          Length = 397

 Score =  268 bits (684), Expect = 8e-72
 Identities = 154/366 (42%), Positives = 210/366 (57%), Gaps = 53/366 (14%)

Query: 10  CLS-LFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVIT 68
           C+S  F Y+T K V+ K+  +G++ R++Q  I++Y V WVFL +K YQ  DT+++S+V+T
Sbjct: 3   CISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVT 62

Query: 69  KVKGVAFTNTSDLGQRIWDVADYVIPAQNEGI-------------PDGACSKD------- 108
           KVKG           R+ DV+DYV P Q   +               G C +        
Sbjct: 63  KVKGSGL-----YANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCV 117

Query: 109 SDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFI 168
           SD   G     G G+ TGRC+   ++ R TCEI  WCP E  +  E P + EAE+FTIFI
Sbjct: 118 SDSQCGPERLPGGGILTGRCVNYSSVLR-TCEIQGWCPTEVDT-VETPIMMEAENFTIFI 175

Query: 169 KNHIRFPKFNFSN-NVMDVKDRSFLKSCHFGP-KNHYCPIFRLGSVIRWAGSDFQDIALE 226
           KN IRFP FNF   N++       +K+C F P K+ +CPI R+G V+++AG DF  +A  
Sbjct: 176 KNSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLART 235

Query: 227 GGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSK-SVSSGYNFRFARYYRDAAGVEFR 285
           GGV+GI I W CDLDKA  +C P YSF+RLD+   K SVS GYNFRFA+YY+   G E+R
Sbjct: 236 GGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYR 295

Query: 286 TLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIKKREFYRD 323
           TL+KA+GIRFDV+V G                       G   CD++L+  +K  + Y+ 
Sbjct: 296 TLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKA 355

Query: 324 KKYEEV 329
           KK+EEV
Sbjct: 356 KKFEEV 361


>gi|4505545 purinergic receptor P2X1 [Homo sapiens]
          Length = 399

 Score =  267 bits (683), Expect = 1e-71
 Identities = 149/393 (37%), Positives = 225/393 (57%), Gaps = 54/393 (13%)

Query: 9   LCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVIT 68
           L   LF+Y T + V+ +NKKVG+++RL+Q  +L Y++ WVFL +KGYQ   + L S+V  
Sbjct: 9   LAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQ-TSSGLISSVSV 67

Query: 69  KVKGVAFTNTSDLGQRIWDVADYVIPAQNEGI---------------------PDGA-CS 106
           K+KG+A T    LG ++WDVADYV PAQ +                       P+G  C 
Sbjct: 68  KLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEHPEGGICK 127

Query: 107 KDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSR-PEEPFLKEAEDFT 165
           +DS C  G+A     G++TG+C+   +  + TCEIF WCP+E     P    L+EAE+FT
Sbjct: 128 EDSGCTPGKAKRKAQGIRTGKCVAFNDTVK-TCEIFGWCPVEVDDDIPRPALLREAENFT 186

Query: 166 IFIKNHIRFPKFNFSN-NVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQDI 223
           +FIKN I FP+F  +  N+++  + + +K+C F    H  CP+F+LG V++ +G +F  +
Sbjct: 187 LFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNFSTL 246

Query: 224 ALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVE 283
           A +GGV+GI I+W+CDLD     C P Y F  L  +  K++S G+NFRFAR++ +  G  
Sbjct: 247 AEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEE--KNLSPGFNFRFARHFVE-NGTN 303

Query: 284 FRTLMKAYGIRFDVMVNGKGAFF----------------------CDLVLIYLIKKREFY 321
           +R L K +GIRFD++V+GK   F                      CDL+L++++ KR +Y
Sbjct: 304 YRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYY 363

Query: 322 RDK--KYEEVRGLEDSSQEAEDEASGLGLSEQL 352
           + K  KY E  G   + ++    +S LGL E +
Sbjct: 364 KQKKFKYAEDMGPGAAERDLAATSSTLGLQENM 396


>gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]
          Length = 404

 Score =  267 bits (682), Expect = 1e-71
 Identities = 146/370 (39%), Positives = 215/370 (58%), Gaps = 54/370 (14%)

Query: 7   KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
           +G   +L+DY+T K ++ +N+++G+LYR +Q  IL Y V +VF+++K YQ+ +T  +S++
Sbjct: 19  RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78

Query: 67  ITKVKGVAFTNTSDLGQRIWDVADYVIP-----------------AQNEG-------IPD 102
           ITKVKG+    TS+   ++WDV +YV P                 +Q +G       + +
Sbjct: 79  ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133

Query: 103 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 162
             C  D+DC AGE    GNG++TGRC+        TCE+F WCP+E  +   +     A 
Sbjct: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 193

Query: 163 DFTIFIKNHIRFPKFNFSNNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQ 221
           +FTI IKN I +PKF+FS   +  +   +LK C F   +  YCPIF+LG ++  AG  F 
Sbjct: 194 NFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFT 253

Query: 222 DIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAG 281
           ++A +GGVIG+ I W+CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   G
Sbjct: 254 ELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-ING 311

Query: 282 VEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIKKRE 319
              RTL+KAYGIR DV+V+G+                      G+F CD +L+  + K +
Sbjct: 312 TTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNK 371

Query: 320 FYRDKKYEEV 329
            Y  KK++++
Sbjct: 372 VYSHKKFDKM 381


>gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]
          Length = 497

 Score =  259 bits (661), Expect = 4e-69
 Identities = 158/462 (34%), Positives = 234/462 (50%), Gaps = 90/462 (19%)

Query: 7   KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
           +G   +L+DY+T K ++ +N+++G+LYR +Q  IL Y V +VF+++K YQ+ +T  +S++
Sbjct: 19  RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78

Query: 67  ITKVKGVAFTNTSDLGQRIWDVADYVIP-----------------AQNEG-------IPD 102
           ITKVKG+    TS+   ++WDV +YV P                 +Q +G       + +
Sbjct: 79  ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133

Query: 103 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 162
             C  D+DC AGE    GNG++TGRC+        TCE+F WCP+E  +   +     A 
Sbjct: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 193

Query: 163 DFTIFIKNHIRFPKFNFSNNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQ 221
           +FTI IKN I +PKF+FS   +  +   +LK C F   +  YCPIF+LG ++  AG  F 
Sbjct: 194 NFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFT 253

Query: 222 DIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAG 281
           ++A +GGVIG+ I W+CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   G
Sbjct: 254 ELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-ING 311

Query: 282 VEFRTLMKAYGIRFDVMVNG---------------------------------------- 301
              RTL+KAYGIR DV+V+G                                        
Sbjct: 312 TTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLWGPSGCGGSTRP 371

Query: 302 --------KGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLT 353
                   +G+F CD +L+  + K + Y  KK+++V      +      +  + L+  L 
Sbjct: 372 LHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKV-----CTPSHPSGSWPVTLARVLG 426

Query: 354 SGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 395
             P   G   + +   PP  + G       G+ C     P R
Sbjct: 427 QAPPEPGHRSEDQHPSPPSGQEGQ-----QGAECGPAFPPLR 463


>gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]
          Length = 415

 Score =  253 bits (645), Expect = 3e-67
 Identities = 135/332 (40%), Positives = 187/332 (56%), Gaps = 57/332 (17%)

Query: 47  WVFLIKKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQNEGI------ 100
           W  L KKGYQ+ D   Q ++ITK+KGV+ T   +LG R+WDVAD+V P Q E +      
Sbjct: 30  WALLAKKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTN 89

Query: 101 ------------------PDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIF 142
                             P   C  D DC  GE  T  +GVKTG+C+      R TCEI+
Sbjct: 90  FLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHR-TCEIW 148

Query: 143 AWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFS-NNVMDVKDRSFLKSCHFGPK- 200
           +WCP+E+   P  P L +A++FT+FIKN + F KFNFS +N ++  D ++ K C + P+ 
Sbjct: 149 SWCPVESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQF 208

Query: 201 NHYCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKL 260
           + YCP+FR+G ++  AG  F+D+AL GG +GI + W+CDLD   S C PHYSF +L  K 
Sbjct: 209 SPYCPVFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSF-QLQEK- 266

Query: 261 SKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGKG----------------- 303
                  YNFR A ++ +  GVE RTL+K YGIRFD++V G+                  
Sbjct: 267 ------SYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAA 320

Query: 304 -----AFFCDLVLIYLIKKREFYRDKKYEEVR 330
                 FFCDL+L+Y+ ++  FY   KYEE +
Sbjct: 321 WLGVVTFFCDLLLLYVDREAHFYWRTKYEEAK 352


>gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]
          Length = 379

 Score =  205 bits (522), Expect = 5e-53
 Identities = 119/319 (37%), Positives = 167/319 (52%), Gaps = 35/319 (10%)

Query: 100 IPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLK 159
           + +  C  D+DC AGE    GNG++TGRC+        TCE+F WCP+E  +   +    
Sbjct: 39  VHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGT 98

Query: 160 EAEDFTIFIKNHIRFPKFNFSNNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGS 218
            A +FTI IKN I +PKF+FS   +  +   +LK C F   +  YCPIF+LG ++  AG 
Sbjct: 99  MAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGE 158

Query: 219 DFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRD 278
            F ++A +GGVIG+ I W+CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+ 
Sbjct: 159 SFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK- 216

Query: 279 AAGVEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIK 316
             G   RTL+KAYGIR DV+V+G+                      G+F CD +L+  + 
Sbjct: 217 INGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMN 276

Query: 317 KREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRG 376
           K + Y  KK+++V      +      +  + L+  L   P   G   + +   PP  + G
Sbjct: 277 KNKVYSHKKFDKV-----CTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEG 331

Query: 377 SSSQKGNGSVCPQLLEPHR 395
                  G+ C     P R
Sbjct: 332 Q-----QGAECGPAFPPLR 345


>gi|29294631 purinergic receptor P2X7 [Homo sapiens]
          Length = 595

 Score =  188 bits (478), Expect = 6e-48
 Identities = 120/339 (35%), Positives = 173/339 (51%), Gaps = 41/339 (12%)

Query: 10  CLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVITK 69
           C  +F Y+T K    ++   G +       I +Y V +  +  K YQ  +  + S+V TK
Sbjct: 7   CSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEPVI-SSVHTK 64

Query: 70  VKGVAFTN-------TSDLGQRIWDVADYVIPAQNEGI-----------------PD--- 102
           VKG+A             L   ++D ADY  P Q                     P+   
Sbjct: 65  VKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCPEYPT 124

Query: 103 --GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLET-SSRPEEPFLK 159
               CS D  C  G       G++TGRC+  E   + TCE+ AWCP+E     P    L 
Sbjct: 125 RRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQK-TCEVSAWCPIEAVEEAPRPALLN 183

Query: 160 EAEDFTIFIKNHIRFPKFNFSN-NVMDVKDRSFLKSCHFGP-KNHYCPIFRLGSVIRWAG 217
            AE+FT+ IKN+I FP  N++  N++         +C F   +N  CPIFRLG + R  G
Sbjct: 184 SAENFTVLIKNNIDFPGHNYTTRNILP----GLNITCTFHKTQNPQCPIFRLGDIFRETG 239

Query: 218 SDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSK-SVSSGYNFRFARYY 276
            +F D+A++GG++GI I W+C+LD+    C P YSF RLD+K +  S+  GYNFR+A+YY
Sbjct: 240 DNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYY 299

Query: 277 RDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLI 315
           ++   VE RTL+K +GIRFD++V G G  F  + L+  I
Sbjct: 300 KE-NNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYI 337


>gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]
          Length = 399

 Score =  187 bits (475), Expect = 1e-47
 Identities = 111/300 (37%), Positives = 156/300 (52%), Gaps = 35/300 (11%)

Query: 119 AGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFN 178
           A  G++TGRC+        TCE+F WCP+E  +   +     A +FTI IKN I +PKF+
Sbjct: 78  APRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFH 137

Query: 179 FSNNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWN 237
           FS   +  +   +LK C F   +  YCPIF+LG ++  AG  F ++A +GGVIG+ I W+
Sbjct: 138 FSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWD 197

Query: 238 CDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDV 297
           CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   G   RTL+KAYGIR DV
Sbjct: 198 CDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-INGTTTRTLIKAYGIRIDV 255

Query: 298 MVNGK----------------------GAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 335
           +V+G+                      G+F CD +L+  + K + Y  KK+++V      
Sbjct: 256 IVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKV-----C 310

Query: 336 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 395
           +      +  + L+  L   P   G   + +   PP  + G       G+ C     P R
Sbjct: 311 TPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ-----QGAECGPAFPPLR 365


>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
          Length = 841

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 18/76 (23%), Positives = 37/76 (48%)

Query: 313 YLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPE 372
           + ++++  Y  +K +E+  +ED ++     A G G  E+   GPG  G+P + +  E   
Sbjct: 631 WALQRKVLYGGRKAKELDKVEDGARAWNGSAEGPGKVEREDRGPGTSGIPVRSQGAEGLL 690

Query: 373 AKRGSSSQKGNGSVCP 388
           A+     + G+ +  P
Sbjct: 691 ARIHHGDRGGSRTALP 706


>gi|167466187 integrin-binding sialoprotein precursor [Homo sapiens]
          Length = 317

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 18/45 (40%), Positives = 23/45 (51%)

Query: 313 YLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPG 357
           YL K   FY   K   V+G  DSS+E  D++S     E+ TS  G
Sbjct: 44  YLYKHAYFYPHLKRFPVQGSSDSSEENGDDSSEEEEEEEETSNEG 88


>gi|239757474 PREDICTED: similar to hCG1785205 [Homo sapiens]
          Length = 362

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 13/38 (34%), Positives = 20/38 (52%)

Query: 347 GLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNG 384
           GL E L +G   LG+PE+ +   P       ++Q G+G
Sbjct: 84  GLQEPLCTGGNSLGIPEESQASSPTLTASSPNAQDGSG 121


>gi|239751984 PREDICTED: similar to hCG1785205 [Homo sapiens]
          Length = 362

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 13/38 (34%), Positives = 20/38 (52%)

Query: 347 GLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNG 384
           GL E L +G   LG+PE+ +   P       ++Q G+G
Sbjct: 84  GLQEPLCTGGNSLGIPEESQASSPTLTASSPNAQDGSG 121


>gi|239746471 PREDICTED: hypothetical protein XP_002343764 [Homo
           sapiens]
          Length = 362

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 13/38 (34%), Positives = 20/38 (52%)

Query: 347 GLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNG 384
           GL E L +G   LG+PE+ +   P       ++Q G+G
Sbjct: 84  GLQEPLCTGGNSLGIPEESQASSPTLTASSPNAQDGSG 121


>gi|116089333 kelch domain containing 7A [Homo sapiens]
          Length = 777

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 2/90 (2%)

Query: 296 DVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSG 355
           D+ + GK       +L+  +  R  Y+ +     R   +   EA++EA G G      + 
Sbjct: 14  DMQLTGKVVLSAAALLLVTVAYR-LYKSRPAPAQRWGGNGQAEAKEEAEGSGQPAVQEAS 72

Query: 356 PG-LLGMPEQQELQEPPEAKRGSSSQKGNG 384
           PG LL  P ++   +  EA +G S +   G
Sbjct: 73  PGVLLRGPRRRRSSKRAEAPQGCSCENPRG 102


>gi|170763517 transforming, acidic coiled-coil containing protein 1
           isoform 1 [Homo sapiens]
          Length = 805

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 8/116 (6%)

Query: 140 EIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSN------NVMDVKDRSFLK 193
           E+   C  +T S+P E  + +    +  +KN    P+ +FS         ++ KD + + 
Sbjct: 104 EVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDIS 163

Query: 194 SCHFGPKNHYCPIFRLGSVIRWAGSD-FQDIALEGGVIGINIEWNCDLD-KAASEC 247
           +       H C     G  +  +  D  QD A+  G +G+ +E + + D KA + C
Sbjct: 164 AVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSC 219


>gi|4758416 golgi-specific brefeldin A resistant guanine nucleotide
           exchange factor 1 [Homo sapiens]
          Length = 1859

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 10/69 (14%)

Query: 331 GLEDSSQEAEDE-------ASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGN 383
           GLE SSQ    E           G S     G   LG+PEQ +LQE    ++   SQ  +
Sbjct: 293 GLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEK---SQSAS 349

Query: 384 GSVCPQLLE 392
               P++LE
Sbjct: 350 VESIPEVLE 358


>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
          Length = 517

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 333 EDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRG-SSSQKGNGSVCPQLL 391
           E+  +E EDE+S  G  E+ +S   L+G        E      G +SS  G+G     L 
Sbjct: 100 EEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLE 159

Query: 392 EP 393
           EP
Sbjct: 160 EP 161


>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
          Length = 503

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 333 EDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRG-SSSQKGNGSVCPQLL 391
           E+  +E EDE+S  G  E+ +S   L+G        E      G +SS  G+G     L 
Sbjct: 100 EEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLE 159

Query: 392 EP 393
           EP
Sbjct: 160 EP 161


>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
          Length = 1989

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 5/55 (9%)

Query: 332 LEDSSQEAEDEASGL-GLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGS 385
           LED     +D  S +   S   +SG GLL  P ++    PP + RG  S  G GS
Sbjct: 22  LEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRR----PPHSARGGGSGGGGGS 72


>gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]
          Length = 498

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 13/45 (28%), Positives = 23/45 (51%)

Query: 59  DTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQNEGIPDG 103
           D  + S  I+K   +A  N +  G  +WD+ D V+  + +G+  G
Sbjct: 363 DHPIMSFTISKNGRLALLNVATQGVHLWDLQDRVLVRKYQGVTQG 407


>gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]
          Length = 514

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 13/45 (28%), Positives = 23/45 (51%)

Query: 59  DTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQNEGIPDG 103
           D  + S  I+K   +A  N +  G  +WD+ D V+  + +G+  G
Sbjct: 379 DHPIMSFTISKNGRLALLNVATQGVHLWDLQDRVLVRKYQGVTQG 423


>gi|33859793 hypothetical protein LOC139212 [Homo sapiens]
          Length = 214

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 16/58 (27%), Positives = 25/58 (43%)

Query: 332 LEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQ 389
           L    ++  D     GLS     GPG +G P+ +EL+  PE    ++    N    P+
Sbjct: 39  LNPEEEDDSDYGQTNGLSTIGAMGPGNIGPPQIEELKVIPETSEENNEDIWNSEEIPE 96


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,302,710
Number of Sequences: 37866
Number of extensions: 692298
Number of successful extensions: 2276
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2181
Number of HSP's gapped (non-prelim): 31
length of query: 397
length of database: 18,247,518
effective HSP length: 104
effective length of query: 293
effective length of database: 14,309,454
effective search space: 4192670022
effective search space used: 4192670022
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.