Guide to the Human Genome
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Search of human proteins with 27545326

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27545326 SWI/SNF related, matrix associated, actin dependent
regulator of chromatin, subfamily b, member 1 isoform a [Homo sapiens]
         (385 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27545326 SWI/SNF related, matrix associated, actin dependent ...   783   0.0  
gi|55956801 SWI/SNF related, matrix associated, actin dependent ...   756   0.0  
gi|12083581 phosphoinositide-specific phospholipase C beta 1 iso...    34   0.25 
gi|33356544 phosphoinositide-specific phospholipase C beta 1 iso...    34   0.25 
gi|90669307 cyclin B3 isoform 3 [Homo sapiens]                         31   1.6  
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    31   2.1  
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    31   2.1  
gi|48255937 CD44 antigen isoform 2 precursor [Homo sapiens]            30   4.8  
gi|48255935 CD44 antigen isoform 1 precursor [Homo sapiens]            30   4.8  
gi|24432077 melanoma associated antigen (mutated) 1-like 1 [Homo...    30   4.8  
gi|56788368 phosphatidylinositol-binding clathrin assembly prote...    29   6.3  
gi|56788366 phosphatidylinositol-binding clathrin assembly prote...    29   6.3  
gi|194328734 PHD finger protein 10 isoform a [Homo sapiens]            29   6.3  
gi|110815815 centlein isoform 1 [Homo sapiens]                         29   6.3  
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...    29   8.2  
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...    29   8.2  
gi|23510323 nephroretinin [Homo sapiens]                               29   8.2  

>gi|27545326 SWI/SNF related, matrix associated, actin dependent
           regulator of chromatin, subfamily b, member 1 isoform a
           [Homo sapiens]
          Length = 385

 Score =  783 bits (2021), Expect = 0.0
 Identities = 385/385 (100%), Positives = 385/385 (100%)

Query: 1   MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEER 60
           MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEER
Sbjct: 1   MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEER 60

Query: 61  KKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYL 120
           KKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYL
Sbjct: 61  KKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYL 120

Query: 121 REQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENA 180
           REQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENA
Sbjct: 121 REQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENA 180

Query: 181 SQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASA 240
           SQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASA
Sbjct: 181 SQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASA 240

Query: 241 IRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSE 300
           IRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSE
Sbjct: 241 IRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSE 300

Query: 301 LGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAE 360
           LGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAE
Sbjct: 301 LGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAE 360

Query: 361 MEKKIRDQDRNTRRMRRLANTAPAW 385
           MEKKIRDQDRNTRRMRRLANTAPAW
Sbjct: 361 MEKKIRDQDRNTRRMRRLANTAPAW 385


>gi|55956801 SWI/SNF related, matrix associated, actin dependent
           regulator of chromatin, subfamily b, member 1 isoform b
           [Homo sapiens]
          Length = 376

 Score =  756 bits (1952), Expect = 0.0
 Identities = 376/385 (97%), Positives = 376/385 (97%), Gaps = 9/385 (2%)

Query: 1   MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEER 60
           MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEER
Sbjct: 1   MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEER 60

Query: 61  KKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYL 120
           KKIVASSH         DHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYL
Sbjct: 61  KKIVASSH---------DHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYL 111

Query: 121 REQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENA 180
           REQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENA
Sbjct: 112 REQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENA 171

Query: 181 SQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASA 240
           SQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASA
Sbjct: 172 SQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASA 231

Query: 241 IRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSE 300
           IRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSE
Sbjct: 232 IRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSE 291

Query: 301 LGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAE 360
           LGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAE
Sbjct: 292 LGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAE 351

Query: 361 MEKKIRDQDRNTRRMRRLANTAPAW 385
           MEKKIRDQDRNTRRMRRLANTAPAW
Sbjct: 352 MEKKIRDQDRNTRRMRRLANTAPAW 376


>gi|12083581 phosphoinositide-specific phospholipase C beta 1 isoform
            a [Homo sapiens]
          Length = 1216

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 4/76 (5%)

Query: 52   RRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVS 111
            RR A +E+  K       KK++P++ DHG +T+   +  L A   ++++D  D++ + + 
Sbjct: 961  RRRAALEKSAK---KDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQL- 1016

Query: 112  ISTEPPTYLREQKAKR 127
            ++     Y  E+  KR
Sbjct: 1017 LNLRQEQYYSEKYQKR 1032


>gi|33356544 phosphoinositide-specific phospholipase C beta 1 isoform
            b [Homo sapiens]
          Length = 1173

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 4/76 (5%)

Query: 52   RRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVS 111
            RR A +E+  K       KK++P++ DHG +T+   +  L A   ++++D  D++ + + 
Sbjct: 961  RRRAALEKSAK---KDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQL- 1016

Query: 112  ISTEPPTYLREQKAKR 127
            ++     Y  E+  KR
Sbjct: 1017 LNLRQEQYYSEKYQKR 1032


>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
          Length = 1395

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 11/100 (11%)

Query: 42  SLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEV----- 96
           +L+KR+ +LW + +T  E++ I   S   + KP+ K     TL      LK S +     
Sbjct: 872 ALFKRHSALWEKPST--EKETIFKESLDLQEKPSIKKE---TLLKKPLALKMSTINEAVL 926

Query: 97  -EEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQWVPTL 135
            E+++  N++      +S + P  L+E    +   ++ TL
Sbjct: 927 FEDMIALNEKPTTGKELSFKEPLALQESPTYKEDTFLKTL 966


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 30/133 (22%), Positives = 51/133 (38%), Gaps = 8/133 (6%)

Query: 52   RRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVS 111
            RRLA   +R+K       KK +   K             L+A++ +E L   DE      
Sbjct: 1473 RRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEDEP----E 1528

Query: 112  ISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDH 171
            + TEPP+         ++ W     +     + +  +++  +NR  +       + FDD 
Sbjct: 1529 VLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKRKNRKNKITPENVQIIFDDP 1588

Query: 172  DPAVIHENASQPE 184
             P     + SQPE
Sbjct: 1589 LPI----SYSQPE 1597


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 30/133 (22%), Positives = 51/133 (38%), Gaps = 8/133 (6%)

Query: 52   RRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVS 111
            RRLA   +R+K       KK +   K             L+A++ +E L   DE      
Sbjct: 1222 RRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEDEP----E 1277

Query: 112  ISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDH 171
            + TEPP+         ++ W     +     + +  +++  +NR  +       + FDD 
Sbjct: 1278 VLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKRKNRKNKITPENVQIIFDDP 1337

Query: 172  DPAVIHENASQPE 184
             P     + SQPE
Sbjct: 1338 LPI----SYSQPE 1346


>gi|48255937 CD44 antigen isoform 2 precursor [Homo sapiens]
          Length = 699

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 3/82 (3%)

Query: 103 NDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKR 162
           +DE + + +IST P  +   ++ +  +QW P+  N    L      T ++RN     +  
Sbjct: 256 DDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGN 315

Query: 163 TFPLCFDDHDPAVIHENASQPE 184
             P   + H P + HE+  + E
Sbjct: 316 WNP---EAHPPLIHHEHHEEEE 334


>gi|48255935 CD44 antigen isoform 1 precursor [Homo sapiens]
          Length = 742

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 3/82 (3%)

Query: 103 NDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKR 162
           +DE + + +IST P  +   ++ +  +QW P+  N    L      T ++RN     +  
Sbjct: 299 DDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGN 358

Query: 163 TFPLCFDDHDPAVIHENASQPE 184
             P   + H P + HE+  + E
Sbjct: 359 WNP---EAHPPLIHHEHHEEEE 377


>gi|24432077 melanoma associated antigen (mutated) 1-like 1 [Homo
           sapiens]
          Length = 637

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 87  SVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVP 146
           S  LL +SE ++ L   D+K +A ++    P+ + E K+ +NS W  T P+ S   D   
Sbjct: 151 SACLLASSESDDSL--YDDKSQAPTMVDTIPSEV-ETKSLQNSSWCETFPSLSEDNDEKE 207

Query: 147 CSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENASQPEVLVPIRLDMEIDGQKLRDAFTW 206
                N+N++      +      +    V  E  + P  L P+  DM I  + L++    
Sbjct: 208 -----NKNKIDISAVMSVHSAVKEESACVKDEKFAPP--LSPLSSDMLIMPKALKEESED 260

Query: 207 NMNEKLMTP---EMFSEILCD 224
              E L  P     FSE + D
Sbjct: 261 TCLETLAVPSECSAFSENIED 281


>gi|56788368 phosphatidylinositol-binding clathrin assembly protein
           isoform 2 [Homo sapiens]
          Length = 610

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 8/89 (8%)

Query: 64  VASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTY--LR 121
           +AS  GKK K +T     TTL+ +V+ L ++ +   L   DE+ K  ++  E      L+
Sbjct: 282 LASLEGKKIKDSTAASRATTLSNAVSSLASTGLS--LTKVDEREKQAALEEEQARLKALK 339

Query: 122 EQKAKRNSQWVPTLPNSSHHLDAVPCSTT 150
           EQ+ K     +   P++S    A P ST+
Sbjct: 340 EQRLKE----LAKKPHTSLTTAASPVSTS 364


>gi|56788366 phosphatidylinositol-binding clathrin assembly protein
           isoform 1 [Homo sapiens]
          Length = 652

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 8/89 (8%)

Query: 64  VASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTY--LR 121
           +AS  GKK K +T     TTL+ +V+ L ++ +   L   DE+ K  ++  E      L+
Sbjct: 282 LASLEGKKIKDSTAASRATTLSNAVSSLASTGLS--LTKVDEREKQAALEEEQARLKALK 339

Query: 122 EQKAKRNSQWVPTLPNSSHHLDAVPCSTT 150
           EQ+ K     +   P++S    A P ST+
Sbjct: 340 EQRLKE----LAKKPHTSLTTAASPVSTS 364


>gi|194328734 PHD finger protein 10 isoform a [Homo sapiens]
          Length = 498

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 15/45 (33%), Positives = 27/45 (60%), Gaps = 2/45 (4%)

Query: 16  KFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEER 60
           K+  ++ GE+YM+  +V  YL +   S  ++YP L RR  + +E+
Sbjct: 78  KWPPDETGEYYMLQEQVSEYLGV--TSFKRKYPDLERRDLSHKEK 120


>gi|110815815 centlein isoform 1 [Homo sapiens]
          Length = 1406

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 5/41 (12%)

Query: 70   KKTKPN-----TKDHGYTTLATSVTLLKASEVEEILDGNDE 105
            KK K N     T  H   TLA S+  +  S++EEILD  D+
Sbjct: 1306 KKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQ 1346


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
           sapiens]
          Length = 1170

 Score = 28.9 bits (63), Expect = 8.2
 Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 10/84 (11%)

Query: 137 NSSHHLDAVPCSTTINRNRMGRDKKRTFPL----CFDDHDPAVIHENASQPEVLVPIRLD 192
           N   HLDA  C T  N   +  DK  T  +        +   + +     P+V +P  LD
Sbjct: 445 NLVRHLDA--CETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLD 502

Query: 193 MEIDGQKLRDAFTWNMNEKLMTPE 216
           + ++G  +  A+T     K++ PE
Sbjct: 503 LIVNGISINSAYT----SKILPPE 522


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
           sapiens]
          Length = 1205

 Score = 28.9 bits (63), Expect = 8.2
 Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 10/84 (11%)

Query: 137 NSSHHLDAVPCSTTINRNRMGRDKKRTFPL----CFDDHDPAVIHENASQPEVLVPIRLD 192
           N   HLDA  C T  N   +  DK  T  +        +   + +     P+V +P  LD
Sbjct: 445 NLVRHLDA--CETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLD 502

Query: 193 MEIDGQKLRDAFTWNMNEKLMTPE 216
           + ++G  +  A+T     K++ PE
Sbjct: 503 LIVNGISINSAYT----SKILPPE 522


>gi|23510323 nephroretinin [Homo sapiens]
          Length = 1426

 Score = 28.9 bits (63), Expect = 8.2
 Identities = 16/33 (48%), Positives = 23/33 (69%), Gaps = 1/33 (3%)

Query: 87  SVTLLKASEVEEILDGNDEKYKAVSISTEPPTY 119
           S+ LL++S   EILD N +  +AVS +TEP T+
Sbjct: 597 SMVLLQSSGFPEILDANKQPAEAVS-ATEPVTF 628


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,537,088
Number of Sequences: 37866
Number of extensions: 638939
Number of successful extensions: 1588
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1579
Number of HSP's gapped (non-prelim): 17
length of query: 385
length of database: 18,247,518
effective HSP length: 104
effective length of query: 281
effective length of database: 14,309,454
effective search space: 4020956574
effective search space used: 4020956574
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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