Search of human proteins with 27370565

Search of human proteins with 27370565

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27370565 aquaporin 11 [Homo sapiens]
         (271 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27370565 aquaporin 11 [Homo sapiens]                               547   e-156
gi|156447037 aquaporin 12B [Homo sapiens]                             113   2e-25
gi|40538880 aquaporin 12A [Homo sapiens]                              103   2e-22
gi|45446752 aquaporin 8 [Homo sapiens]                                 36   0.031
gi|24119274 voltage gated channel like 1 [Homo sapiens]                32   0.77 
gi|22538420 aquaporin 10 [Homo sapiens]                                30   1.7  
gi|13236585 fibronectin type III and SPRY domain containing 1 [H...    29   3.8  
gi|25914749 ATP-binding cassette, sub-family C, member 10 [Homo ...    29   5.0  

>gi|27370565 aquaporin 11 [Homo sapiens]
          Length = 271

 Score =  547 bits (1410), Expect = e-156
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 1   MSPLLGLRSELQDTCTSLGLMLSVVLLMGLARVVARQQLHRPVAHAFVLEFLATFQLCCC 60
           MSPLLGLRSELQDTCTSLGLMLSVVLLMGLARVVARQQLHRPVAHAFVLEFLATFQLCCC
Sbjct: 1   MSPLLGLRSELQDTCTSLGLMLSVVLLMGLARVVARQQLHRPVAHAFVLEFLATFQLCCC 60

Query: 61  THELQLLSEQHPAHPTWTLTLVYFFSLVHGLTLVGTSSNPCGVMMQMMLGGMSPETGAVR 120
           THELQLLSEQHPAHPTWTLTLVYFFSLVHGLTLVGTSSNPCGVMMQMMLGGMSPETGAVR
Sbjct: 61  THELQLLSEQHPAHPTWTLTLVYFFSLVHGLTLVGTSSNPCGVMMQMMLGGMSPETGAVR 120

Query: 121 LLAQLVSALCSRYCTSALWSLGLTQYHVSERSFACKNPIRVDLLKAVITEAVCSFLFHSA 180
           LLAQLVSALCSRYCTSALWSLGLTQYHVSERSFACKNPIRVDLLKAVITEAVCSFLFHSA
Sbjct: 121 LLAQLVSALCSRYCTSALWSLGLTQYHVSERSFACKNPIRVDLLKAVITEAVCSFLFHSA 180

Query: 181 LLHFQEVRTKLRIHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYW 240
           LLHFQEVRTKLRIHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYW
Sbjct: 181 LLHFQEVRTKLRIHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYW 240

Query: 241 LAPSLGILLMILMFSFFLPWLHNNHTINKKE 271
           LAPSLGILLMILMFSFFLPWLHNNHTINKKE
Sbjct: 241 LAPSLGILLMILMFSFFLPWLHNNHTINKKE 271


>gi|156447037 aquaporin 12B [Homo sapiens]
          Length = 307

 Score =  113 bits (283), Expect = 2e-25
 Identities = 75/251 (29%), Positives = 112/251 (44%), Gaps = 6/251 (2%)

Query: 17  SLGLMLSVVLLMGLARVVARQQLHRPVAHAFVLEFLATFQLCCCTHELQLLSEQHP---- 72
           SL    +   L   AR  ++  L       F  E +   QL  C  E++ L E  P    
Sbjct: 7   SLSFFFATFTLCEAARRASKALLPVGAYEVFAREAVGAVQLGACFLEMRTLVELGPWAGD 66

Query: 73  AHPTWTLTLVYFFSLVHGLTLVGTSSNPCGVMMQMMLGGMSPETGAVRLLAQLVSALCSR 132
             P   LTL++   L HG+TL G S+NP   + + ++   S     ++L AQ +    + 
Sbjct: 67  FGPDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEESLPGTLLKLAAQGLGMQAAC 126

Query: 133 YCTSALWSLGLTQYHVSERSFA--CKNPIRVDLLKAVITEAVCSFLFHSALLHFQEVRTK 190
             T   W+  L+  H+ +   A  C + +R  +    + EA C+F FH  LLH +     
Sbjct: 127 TLTRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPA 186

Query: 191 LRIHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYWLAPSLGILLM 250
                +A L+T   Y  G  T A FNPALA S+ F C      ++  VYWL P  G++L 
Sbjct: 187 YSGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLA 246

Query: 251 ILMFSFFLPWL 261
           +L+    LP L
Sbjct: 247 VLLHQGRLPHL 257


>gi|40538880 aquaporin 12A [Homo sapiens]
          Length = 295

 Score =  103 bits (256), Expect = 2e-22
 Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 2/189 (1%)

Query: 75  PTWTLTLVYFFSLVHGLTLVGTSSNPCGVMMQMMLGGMSPETGAVRLLAQLVSALCSRYC 134
           P   LTL++   L HG+TL G S+NP   + + ++   S     ++L AQ +    +   
Sbjct: 57  PDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTL 116

Query: 135 TSALWSLGLTQYHVSERSFA--CKNPIRVDLLKAVITEAVCSFLFHSALLHFQEVRTKLR 192
               W+  L+  H+ +   A  C + +R  +    + EA C+F FH  LLH +       
Sbjct: 117 MRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYS 176

Query: 193 IHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYWLAPSLGILLMIL 252
              +A L+T   Y  G  T A FNPALA S+ F C      ++  VYWL P  G++L +L
Sbjct: 177 GPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVL 236

Query: 253 MFSFFLPWL 261
           +    LP L
Sbjct: 237 LHQGRLPHL 245


>gi|45446752 aquaporin 8 [Homo sapiens]
          Length = 261

 Score = 36.2 bits (82), Expect = 0.031
 Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 34/194 (17%)

Query: 86  SLVHGLTL----------VGTSSNPCGVMMQMMLGGMSPETGAVRLLAQLVSALCSRYCT 135
           +L HGL L           G   NP   +  M++GG++     V LL   VS L      
Sbjct: 69  ALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLN----LVMLLPYWVSQLLGGMLG 124

Query: 136 SAL----------WSL-GLTQYHVSERSFACKNPIRVDLLKAVITEAVCSFLFHSALLHF 184
           +AL          W+  G     V E+       +   +L  ++  AVC    +      
Sbjct: 125 AALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAIN------ 178

Query: 185 QEVRTKLRIHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYWLAPS 244
           ++ +  L    +   +T  + AGG ++G   NPA A     +        F  +YWL P 
Sbjct: 179 EKTKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHW---NFHWIYWLGPL 235

Query: 245 LGILLMILMFSFFL 258
           L  LL+ L+   F+
Sbjct: 236 LAGLLVGLLIRCFI 249


>gi|24119274 voltage gated channel like 1 [Homo sapiens]
          Length = 1738

 Score = 31.6 bits (70), Expect = 0.77
 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 17/108 (15%)

Query: 138 LWSLGLTQYHVSERSFACKNPIRVDLLKAVITEA-VCSFLFHSALLHFQEVRTKLRIHLL 196
           +W LG T Y  S          + +LL  + T   V   L+HS   +FQ +R    I + 
Sbjct: 437 IWCLGFTGYISSSLH-------KFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKIS 489

Query: 197 AALITFL--VYAGGSLTGA--VFNPAL-----ALSLHFMCFDEAFPQF 235
            AL  F+  ++  G   G+  VF  +L     A+SL   CF E   +F
Sbjct: 490 PALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRF 537


>gi|22538420 aquaporin 10 [Homo sapiens]
          Length = 301

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 9/53 (16%)

Query: 200 ITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYWLAPSLGILLMIL 252
           +T  +Y GG+++GA  NPA +L+   MC     P      W+   + IL+ +L
Sbjct: 66  VTIAIYVGGNVSGAHLNPAFSLA---MCIVGRLP------WVKLPIYILVQLL 109


>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
           sapiens]
          Length = 496

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 7/70 (10%)

Query: 135 TSALWSLGLTQYHVSERSFACKNPIRVDLLKAVITEAV---CSFLFHSALLHFQEVRTKL 191
           T+A W L +  +   + SF  K+  +V +L A + + +   C F  H  LL F   RTK 
Sbjct: 387 TAASWCLHVNNW--LQVSFTAKHANKVKVLDAPVPDCLGVHCDF--HQGLLSFYNARTKQ 442

Query: 192 RIHLLAALIT 201
            +H      T
Sbjct: 443 VLHTFKTRFT 452


>gi|25914749 ATP-binding cassette, sub-family C, member 10 [Homo
            sapiens]
          Length = 1464

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 14/99 (14%)

Query: 163  LLKAVITEAVCSFLFHSALLHFQEVRTKLRIHLLAALITFLVYAGGSLTGAVFNPALALS 222
            LL+AV+  A    L  +A LH      +L   +L A +TF      + TG + N     S
Sbjct: 955  LLRAVLFAA--GTLQAAATLH-----RRLLHRVLMAPVTFF---NATPTGRILN---RFS 1001

Query: 223  LHFMCFDEAFPQFFIVYWLAPSLGILLMILMFSFFLPWL 261
                C D++ P F +   LA + G+L ++ +    LPWL
Sbjct: 1002 SDVACADDSLP-FILNILLANAAGLLGLLAVLGSGLPWL 1039


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.331    0.139    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,283,927
Number of Sequences: 37866
Number of extensions: 358017
Number of successful extensions: 1022
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1012
Number of HSP's gapped (non-prelim): 9
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.