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Search of human proteins with 25777640
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
(375 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 747 0.0
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 747 0.0
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 747 0.0
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 445 e-125
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 346 2e-95
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 346 2e-95
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 346 2e-95
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 346 2e-95
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 346 2e-95
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 285 4e-77
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 281 9e-76
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 274 1e-73
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 272 3e-73
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 272 3e-73
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 272 3e-73
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 266 2e-71
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 266 2e-71
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 258 8e-69
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 256 3e-68
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 256 3e-68
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 253 2e-67
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 252 3e-67
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 242 3e-64
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 238 5e-63
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 237 1e-62
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 227 2e-59
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 216 2e-56
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 216 2e-56
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 216 2e-56
gi|71061468 centromere protein E [Homo sapiens] 32 1.2
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 747 bits (1929), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60
MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID
Sbjct: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60
Query: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120
MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF
Sbjct: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120
Query: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180
SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF
Sbjct: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180
Query: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240
SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD
Sbjct: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240
Query: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300
SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY
Sbjct: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300
Query: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360
IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ
Sbjct: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360
Query: 361 RERELRTLLLQQSNV 375
RERELRTLLLQQSNV
Sbjct: 361 RERELRTLLLQQSNV 375
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 747 bits (1929), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60
MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID
Sbjct: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60
Query: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120
MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF
Sbjct: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120
Query: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180
SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF
Sbjct: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180
Query: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240
SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD
Sbjct: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240
Query: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300
SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY
Sbjct: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300
Query: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360
IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ
Sbjct: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360
Query: 361 RERELRTLLLQQSNV 375
RERELRTLLLQQSNV
Sbjct: 361 RERELRTLLLQQSNV 375
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 747 bits (1929), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60
MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID
Sbjct: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60
Query: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120
MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF
Sbjct: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120
Query: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180
SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF
Sbjct: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180
Query: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240
SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD
Sbjct: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240
Query: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300
SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY
Sbjct: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300
Query: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360
IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ
Sbjct: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360
Query: 361 RERELRTLLLQQSNV 375
RERELRTLLLQQSNV
Sbjct: 361 RERELRTLLLQQSNV 375
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 445 bits (1144), Expect = e-125
Identities = 231/363 (63%), Positives = 283/363 (77%), Gaps = 11/363 (3%)
Query: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTW 78
G G++ R RV++K G SNVR++ + LYL+DLWTT IDM+WRYKL LF+ATF TW
Sbjct: 22 GPGIR--RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTW 79
Query: 79 FLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEE 138
FLFGV++Y +A HGDL +P +NHTPC+++V +LTGAFLFSLESQTTIGYG R I+EE
Sbjct: 80 FLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEE 139
Query: 139 CPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQ 198
CP AI LL+AQLV+TT++EIFITGTFLAKIARPKKRAETI+FS AV+ NGK CL+I+
Sbjct: 140 CPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIR 199
Query: 199 VANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVL 258
VANMRKSLLI CQ++GKLLQTH TKEGE I LNQ V F VD++S+SPFLILP+TFYHV+
Sbjct: 200 VANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVV 259
Query: 259 DETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLS 318
DETSPL+DL P E +FELV++L+ TVESTSA CQ RTSY+PEEI WG+EF P +SLS
Sbjct: 260 DETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLS 318
Query: 319 KNGKYVADFSQFEQIRK--SP----DCTFYCADSEKQQLEEKYRQEDQRERELRTLLLQQ 372
+GKY+ADFS F+Q+ K SP D T D EK +LEE R +Q E+E L ++
Sbjct: 319 ASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEESLR--EQAEKEGSALSVRI 376
Query: 373 SNV 375
SNV
Sbjct: 377 SNV 379
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 346 bits (887), Expect = 2e-95
Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%)
Query: 21 GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79
G R R++SK G N+ V+ ++ D+WTTV+D+KWRYK+T+F F+ +WF
Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74
Query: 80 LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139
FG+++YA+A+IH DL P +NHTPC+ ++ LT AFLFSLE+Q TIGYG R +TE+C
Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199
AIFLL+ Q ++ +I F+ G LAKI+RPKKRA+TI FS AVI+K+ GKLCL+I+V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259
AN+RKSLLI + GKLL+T VT EGE I+L+Q + F VD+ +E+ F I P+T YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254
Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319
SP + + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314
Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348
GKY DF F + ++P C C +EK
Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 346 bits (887), Expect = 2e-95
Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%)
Query: 21 GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79
G R R++SK G N+ V+ ++ D+WTTV+D+KWRYK+T+F F+ +WF
Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74
Query: 80 LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139
FG+++YA+A+IH DL P +NHTPC+ ++ LT AFLFSLE+Q TIGYG R +TE+C
Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199
AIFLL+ Q ++ +I F+ G LAKI+RPKKRA+TI FS AVI+K+ GKLCL+I+V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259
AN+RKSLLI + GKLL+T VT EGE I+L+Q + F VD+ +E+ F I P+T YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254
Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319
SP + + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314
Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348
GKY DF F + ++P C C +EK
Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 346 bits (887), Expect = 2e-95
Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%)
Query: 21 GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79
G R R++SK G N+ V+ ++ D+WTTV+D+KWRYK+T+F F+ +WF
Sbjct: 34 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 93
Query: 80 LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139
FG+++YA+A+IH DL P +NHTPC+ ++ LT AFLFSLE+Q TIGYG R +TE+C
Sbjct: 94 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 153
Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199
AIFLL+ Q ++ +I F+ G LAKI+RPKKRA+TI FS AVI+K+ GKLCL+I+V
Sbjct: 154 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 213
Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259
AN+RKSLLI + GKLL+T VT EGE I+L+Q + F VD+ +E+ F I P+T YHV+D
Sbjct: 214 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 273
Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319
SP + + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K
Sbjct: 274 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 333
Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348
GKY DF F + ++P C C +EK
Sbjct: 334 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 363
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 346 bits (887), Expect = 2e-95
Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%)
Query: 21 GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79
G R R++SK G N+ V+ ++ D+WTTV+D+KWRYK+T+F F+ +WF
Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74
Query: 80 LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139
FG+++YA+A+IH DL P +NHTPC+ ++ LT AFLFSLE+Q TIGYG R +TE+C
Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199
AIFLL+ Q ++ +I F+ G LAKI+RPKKRA+TI FS AVI+K+ GKLCL+I+V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259
AN+RKSLLI + GKLL+T VT EGE I+L+Q + F VD+ +E+ F I P+T YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254
Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319
SP + + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314
Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348
GKY DF F + ++P C C +EK
Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 346 bits (887), Expect = 2e-95
Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%)
Query: 21 GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79
G R R++SK G N+ V+ ++ D+WTTV+D+KWRYK+T+F F+ +WF
Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74
Query: 80 LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139
FG+++YA+A+IH DL P +NHTPC+ ++ LT AFLFSLE+Q TIGYG R +TE+C
Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199
AIFLL+ Q ++ +I F+ G LAKI+RPKKRA+TI FS AVI+K+ GKLCL+I+V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259
AN+RKSLLI + GKLL+T VT EGE I+L+Q + F VD+ +E+ F I P+T YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254
Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319
SP + + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314
Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348
GKY DF F + ++P C C +EK
Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 285 bits (730), Expect = 4e-77
Identities = 142/333 (42%), Positives = 216/333 (64%), Gaps = 11/333 (3%)
Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
R R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFG+I+
Sbjct: 43 RNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIF 102
Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
+ IA HGDLEP E TPC+M+V AFLFS+E+QTTIGYG+R +TEECP A+F+
Sbjct: 103 WVIAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFM 161
Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
+VAQ ++ +I+ F+ G +AK+ARPKKRA+T+ FSH AV+ ++GKLCL+ +V N+RKS
Sbjct: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
+++ + +L++ VT+EGE I L+Q + D + FL+ P+T H +DE SPL
Sbjct: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281
Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
++ Q+L+ +FE+VV+L VE+T+ Q+R+SY+ EI WG F PV+ KN +Y
Sbjct: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340
Query: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
D+S F ++ +P C S K +E K+
Sbjct: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 281 bits (718), Expect = 9e-76
Identities = 142/333 (42%), Positives = 214/333 (64%), Gaps = 11/333 (3%)
Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
R R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI+
Sbjct: 43 RNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 102
Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
+ IA HGDLEP E TPC+M+V AFLFS+E+QTTIGYG+R +TEEC A+F+
Sbjct: 103 WVIAVAHGDLEPAEG-HGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFM 161
Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
+VAQ ++ +I+ F+ G +AK+ARPKKRA T+ FSH AV+ ++GKLCL+ +V N+RKS
Sbjct: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
+++ + +L++ VT+EGE I L+Q + D + FL+ P+T H +DE SPL
Sbjct: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281
Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
++ Q+L+ +FE+VV+L VE+T+ Q+R+SY+ EI WG F PV+ KN +Y
Sbjct: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340
Query: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
D+S F ++ +P C S K +E K+
Sbjct: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 274 bits (700), Expect = 1e-73
Identities = 139/330 (42%), Positives = 212/330 (64%), Gaps = 7/330 (2%)
Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
R R + K GH NV+ V YL D++TT +D++WR+ L +F FV++W FG ++
Sbjct: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
+ IA +HGDL+ + C+ +V+S T AFLFS+E+QTTIGYG R +T+ECP A+F+
Sbjct: 104 WLIALLHGDLDASK---EGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM 160
Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
+V Q ++ +I+ FI G +AK+A+PKKR ET+ FSH AVI ++GKLCL+ +V N+RKS
Sbjct: 161 VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKS 220
Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
L++ + +LL++ +T EGE I L+Q + DS + FL+ P+T H +DE SPL
Sbjct: 221 HLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLY 280
Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
DL+ Q++ +FE+VV+L VE+T+ Q R+SY+ EI WG + PV+ K+ Y
Sbjct: 281 DLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKH-YYKV 339
Query: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEKY 355
D+S+F + + P+ T C S + E+KY
Sbjct: 340 DYSRFHKTYEVPN-TPLC--SARDLAEKKY 366
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 272 bits (696), Expect = 3e-73
Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%)
Query: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI++
Sbjct: 45 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104
Query: 88 IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147
IA HGDLEP E TPC+M+V AFLFS+++Q TI YG+R +TEECP A+F++V
Sbjct: 105 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 163
Query: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207
AQ ++ +I F+ G +AK+ RPKKRA+T+ FSH AV+ ++GKLC + +V N+RKS +
Sbjct: 164 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 223
Query: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267
++ + +L++ VTKEGE I L+Q + D + FL+ P+T H +DE SPL +
Sbjct: 224 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 283
Query: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327
+ Q+L+ +FE+V++L VE+T+ Q+R+SY+ EI WG F PV L + +Y D+
Sbjct: 284 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 341
Query: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
F ++ +P C S K +E K+
Sbjct: 342 LHFHKTYEVPSTPRC------SAKDLVENKF 366
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 272 bits (696), Expect = 3e-73
Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%)
Query: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI++
Sbjct: 147 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 206
Query: 88 IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147
IA HGDLEP E TPC+M+V AFLFS+++Q TI YG+R +TEECP A+F++V
Sbjct: 207 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 265
Query: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207
AQ ++ +I F+ G +AK+ RPKKRA+T+ FSH AV+ ++GKLC + +V N+RKS +
Sbjct: 266 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 325
Query: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267
++ + +L++ VTKEGE I L+Q + D + FL+ P+T H +DE SPL +
Sbjct: 326 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 385
Query: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327
+ Q+L+ +FE+V++L VE+T+ Q+R+SY+ EI WG F PV L + +Y D+
Sbjct: 386 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 443
Query: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
F ++ +P C S K +E K+
Sbjct: 444 LHFHKTYEVPSTPRC------SAKDLVENKF 468
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 272 bits (696), Expect = 3e-73
Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%)
Query: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI++
Sbjct: 45 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104
Query: 88 IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147
IA HGDLEP E TPC+M+V AFLFS+++Q TI YG+R +TEECP A+F++V
Sbjct: 105 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 163
Query: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207
AQ ++ +I F+ G +AK+ RPKKRA+T+ FSH AV+ ++GKLC + +V N+RKS +
Sbjct: 164 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 223
Query: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267
++ + +L++ VTKEGE I L+Q + D + FL+ P+T H +DE SPL +
Sbjct: 224 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 283
Query: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327
+ Q+L+ +FE+V++L VE+T+ Q+R+SY+ EI WG F PV L + +Y D+
Sbjct: 284 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 341
Query: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
F ++ +P C S K +E K+
Sbjct: 342 LHFHKTYEVPSTPRC------SAKDLVENKF 366
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 266 bits (681), Expect = 2e-71
Identities = 134/336 (39%), Positives = 210/336 (62%), Gaps = 19/336 (5%)
Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
+ R R + K+G NV + Y+ D++TT +D +WRY L +F+A F+++W FG
Sbjct: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
Query: 83 VIYYAIAFIHGDLE--PGEPISNHT-------------PCIMKVDSLTGAFLFSLESQTT 127
++++ IAF HGDLE PG P + PCIM V+ GAFLFS+E+QTT
Sbjct: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
Query: 128 IGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVIT 187
IGYG R +TEECP A+ +V Q ++ +I+ F+ GT +AK+ARPKKRA+T+ FSH AVI+
Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
Query: 188 KQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPF 247
++GKLCL+ +V N+RKS +++ + +L++ ++T+EGE + L+Q + D + F
Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
Query: 248 LILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYW 307
L+ P+ H +DE SPL + + L+ ++FE+VV+L VE+T+ Q+R+SY+ EI W
Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
Query: 308 GFEFVPVVSLSKNGKYVADFSQFE---QIRKSPDCT 340
G F PVV + Y D+S+F ++ +P C+
Sbjct: 315 GHRFEPVV-FEEKSHYKVDYSRFHKTYEVAGTPCCS 349
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 266 bits (681), Expect = 2e-71
Identities = 134/336 (39%), Positives = 210/336 (62%), Gaps = 19/336 (5%)
Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
+ R R + K+G NV + Y+ D++TT +D +WRY L +F+A F+++W FG
Sbjct: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
Query: 83 VIYYAIAFIHGDLE--PGEPISNHT-------------PCIMKVDSLTGAFLFSLESQTT 127
++++ IAF HGDLE PG P + PCIM V+ GAFLFS+E+QTT
Sbjct: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
Query: 128 IGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVIT 187
IGYG R +TEECP A+ +V Q ++ +I+ F+ GT +AK+ARPKKRA+T+ FSH AVI+
Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
Query: 188 KQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPF 247
++GKLCL+ +V N+RKS +++ + +L++ ++T+EGE + L+Q + D + F
Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
Query: 248 LILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYW 307
L+ P+ H +DE SPL + + L+ ++FE+VV+L VE+T+ Q+R+SY+ EI W
Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
Query: 308 GFEFVPVVSLSKNGKYVADFSQFE---QIRKSPDCT 340
G F PVV + Y D+S+F ++ +P C+
Sbjct: 315 GHRFEPVV-FEEKSHYKVDYSRFHKTYEVAGTPCCS 349
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 258 bits (658), Expect = 8e-69
Identities = 129/320 (40%), Positives = 198/320 (61%), Gaps = 7/320 (2%)
Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
K R R M KSG NV V Y YL DL+TT++D+KWR+ L +F + +TW FG
Sbjct: 47 KKPRQRYMEKSGKCNVHHGNVQETYR-YLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105
Query: 83 VIYYAIAFIHGDLEP-GEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPH 141
I++ IA+I GDL+ G+ PC+ + AFLFS+E++TTIGYG R ITE+CP
Sbjct: 106 FIWWLIAYIRGDLDHVGD--QEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPE 163
Query: 142 AIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVAN 201
I LL+ Q ++ +++ F+ G KI++PKKRAET+ FS+ AVI+ ++ KLCL+ +V +
Sbjct: 164 GIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGD 223
Query: 202 MRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDET 261
+R S +++ + KL+++ TKEGE I LNQ + D+ + FL+ P+ H +++
Sbjct: 224 LRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQK 283
Query: 262 SPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321
SP +++ L ++EFE+VV+L VE+T CQ+R+SY+ E+ WG F PV++L K G
Sbjct: 284 SPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-G 342
Query: 322 KYVADFSQFEQI--RKSPDC 339
Y D++ F +P C
Sbjct: 343 FYEVDYNTFHDTYETNTPSC 362
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 256 bits (653), Expect = 3e-68
Identities = 133/329 (40%), Positives = 199/329 (60%), Gaps = 5/329 (1%)
Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
R R + K GH NVR + G YL DL+TT +D++WR+ LF+ +F+ +W LFG+ +
Sbjct: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
+ IA +HGDL P + PC V S AFLF+LE+QT+IGYGVRS+TEECP A+
Sbjct: 109 WLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAA 165
Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
+V Q + +++ F+ G +AK+A+PKKR ET+ FS AV+ ++ +LCL+ +V N+R+S
Sbjct: 166 VVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRS 225
Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
L++ + +LLQ VT EGE I L+ V D ++ FL+ P+T H +D SPL
Sbjct: 226 HLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLY 285
Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
+L L +FELVV+L VE+T+ Q R+SY+P E+ WG F PV+ + +Y
Sbjct: 286 ELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL-FQRGSQYEV 344
Query: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEK 354
D+ F + + P T C+ E + E+
Sbjct: 345 DYRHFHRTYEVPG-TPVCSAKELDERAEQ 372
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 256 bits (653), Expect = 3e-68
Identities = 133/329 (40%), Positives = 199/329 (60%), Gaps = 5/329 (1%)
Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
R R + K GH NVR + G YL DL+TT +D++WR+ LF+ +F+ +W LFG+ +
Sbjct: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
+ IA +HGDL P + PC V S AFLF+LE+QT+IGYGVRS+TEECP A+
Sbjct: 109 WLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAA 165
Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
+V Q + +++ F+ G +AK+A+PKKR ET+ FS AV+ ++ +LCL+ +V N+R+S
Sbjct: 166 VVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRS 225
Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
L++ + +LLQ VT EGE I L+ V D ++ FL+ P+T H +D SPL
Sbjct: 226 HLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLY 285
Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
+L L +FELVV+L VE+T+ Q R+SY+P E+ WG F PV+ + +Y
Sbjct: 286 ELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL-FQRGSQYEV 344
Query: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEK 354
D+ F + + P T C+ E + E+
Sbjct: 345 DYRHFHRTYEVPG-TPVCSAKELDERAEQ 372
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 253 bits (646), Expect = 2e-67
Identities = 123/329 (37%), Positives = 201/329 (61%), Gaps = 2/329 (0%)
Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
K R R + K+G NV+ + YL DL+TT++D+KWR+ L +F T+ + W
Sbjct: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
Query: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
+++ IA+ GDL + N+TPC+ V + AFLF +E++ TIGYG R IT++CP
Sbjct: 100 SMWWVIAYTRGDLNKAH-VGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEG 158
Query: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
I L + Q ++ ++++ F+ G K+++PKKRAET+ FS AVI+ ++GKL L+ +V N+
Sbjct: 159 IILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNL 218
Query: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
R S ++ Q+ KLL++ T EGE + L+Q + + ++ FL+ P+T HV+D S
Sbjct: 219 RNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKS 278
Query: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322
P DL+ ++++ ++FE+VV+L VE+T CQ+RTSY +E+ WG F PV+SL + G
Sbjct: 279 PFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEGF 337
Query: 323 YVADFSQFEQIRKSPDCTFYCADSEKQQL 351
+ D+SQF + P + + E+ L
Sbjct: 338 FKVDYSQFHATFEVPTPPYSVKEQEEMLL 366
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 252 bits (644), Expect = 3e-67
Identities = 125/320 (39%), Positives = 200/320 (62%), Gaps = 3/320 (0%)
Query: 13 LVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAA 72
L +H + K R + K G NV V Y YL D++TT++D+KWR+ L +F
Sbjct: 40 LPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYR-YLTDIFTTLVDLKWRFNLLIFVM 98
Query: 73 TFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGV 132
+ +TW FG+I++ IA+I GD++ E S TPC+ ++ AFLFS+E++TTIGYG
Sbjct: 99 VYTVTWLFFGMIWWLIAYIRGDMDHIEDPS-WTPCVTNLNGFVSAFLFSIETETTIGYGY 157
Query: 133 RSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGK 192
R IT++CP I LL+ Q V+ +++ F+ G KI++PKKRAET+ FS AVI+ ++GK
Sbjct: 158 RVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGK 217
Query: 193 LCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPM 252
LCL+ +V ++R S +++ + KL+++ T EGE I LNQ + + + FL+ P+
Sbjct: 218 LCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPL 277
Query: 253 TFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFV 312
H +++ SP +++ L ++E E+VV+L VE+T CQ+R+SYI EI WG+ F
Sbjct: 278 IISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFT 337
Query: 313 PVVSLSKNGKYVADFSQFEQ 332
PV++L ++G Y D++ F +
Sbjct: 338 PVLTL-EDGFYEVDYNSFHE 356
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 242 bits (618), Expect = 3e-64
Identities = 126/333 (37%), Positives = 201/333 (60%), Gaps = 7/333 (2%)
Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
+ R R +SK G+ NV + +LQD++TT++D+KW + L +F +F+ +W LF
Sbjct: 29 RQRRARFVSKKGNCNVAHKNIRE-QGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
Query: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
+ ++ IAF HGDL P E + PC+ + S + AFLFS+E Q TIG+G R +TEECP A
Sbjct: 88 MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145
Query: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
I +L+ Q ++ +I + G K A+ +RAET+ FS AVI ++G+LC +++V ++
Sbjct: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205
Query: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
RKS++I + ++++ + EGE + L+Q + S FL+ P+ YHV+D S
Sbjct: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265
Query: 263 PLRDLTPQNL-KEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321
PL DL P +L ++ E++V+L VE+T Q+RTSY+ +EI WG FVP+V+ ++G
Sbjct: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVA-EEDG 324
Query: 322 KYVADFSQFEQIRK--SPDCTFYCADSEKQQLE 352
+Y D+S+F K +P CT D + LE
Sbjct: 325 RYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLE 357
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 238 bits (608), Expect = 5e-63
Identities = 117/315 (37%), Positives = 193/315 (61%), Gaps = 3/315 (0%)
Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
+ R R + K G NV+ V Y YL DL+TT++D++WR L F + +TW FG
Sbjct: 18 RRGRQRYVEKDGRCNVQQGNVRETYR-YLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76
Query: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
I++ IA+ GDLE E + TPC+ ++ AFLFS+E++TTIGYG R IT++CP
Sbjct: 77 AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
Query: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
I LL+ Q ++ +++ F+ G KI++P KRA T+ FS AV++ ++G+LCL+ +V ++
Sbjct: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
Query: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
R S +++ + KL+++ T EGE I L+Q + D+ + FL+ P+ H +D S
Sbjct: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
Query: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322
P + + + L+ +FE+VV+L VE+T CQ+R+SY+ +E+ WG F V++L ++G
Sbjct: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTL-EDGF 314
Query: 323 YVADFSQFEQIRKSP 337
Y D++ F + + P
Sbjct: 315 YEVDYASFHETFEVP 329
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 237 bits (604), Expect = 1e-62
Identities = 135/326 (41%), Positives = 194/326 (59%), Gaps = 20/326 (6%)
Query: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
R+++K GHS +++D L YL+D W ++DM+WR+ + +F+A+FV+ W +F V++Y
Sbjct: 19 RMVTKDGHSTLQMDGAQR-GLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
Query: 88 IAFIHGDLEPGE--PISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
+A ++GDLE P NHT C+ + S T AF FSLE+Q TIGYG + +CP AI L
Sbjct: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
L Q+++ ++E FITG F+AKIARPK RA +I+F+ AV+ +GK L+ QVAN R S
Sbjct: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD--SSSESPFLILPMTFYHVLDETSP 263
L ++S L Q E E L Q +V FH+D SS E PF I P+T+YH + +SP
Sbjct: 198 PLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252
Query: 264 LRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKY 323
L L Q+ FELVV L+A E T +CQ RTSY+P EI F +++ G+Y
Sbjct: 253 LATLL-QHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311
Query: 324 VADFSQFEQ---------IRKSPDCT 340
F++ + KSP+ T
Sbjct: 312 QIKMENFDKTVPEFPTPLVSKSPNRT 337
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 227 bits (578), Expect = 2e-59
Identities = 123/329 (37%), Positives = 196/329 (59%), Gaps = 21/329 (6%)
Query: 26 RPRVMSKSG-----HSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFL 80
+ R ++KSG H N+R +LQD++TT++D+KWR+ L +F +F+ +W L
Sbjct: 33 KARFIAKSGACNLAHKNIREQG------RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLL 86
Query: 81 FGVIYYAIAFIHGDL-----EPGEPISN--HTPCIMKVDSLTGAFLFSLESQTTIGYGVR 133
F ++++ +AF HGD+ + G S T C+ V S T AFLFS+E Q TIG+G R
Sbjct: 87 FAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGR 146
Query: 134 SITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKL 193
+TEECP AI +L+ Q ++ +I + G K A+ +RAET+ FS AVI +NGKL
Sbjct: 147 MMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKL 206
Query: 194 CLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMT 253
C + +V ++RKS++I + ++++ T EGE + ++Q + S + FL+ P+
Sbjct: 207 CFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLI 266
Query: 254 FYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVP 313
HV+D+ SPL D++ +L ++ E++V+L VE+T Q+RTSYI EEI WG FV
Sbjct: 267 ICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVS 326
Query: 314 VVSLSKNGKYVADFSQFEQIRK--SPDCT 340
+V+ + G Y D+S+F K +P C+
Sbjct: 327 IVT-EEEGVYSVDYSKFGNTVKVAAPRCS 354
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 216 bits (551), Expect = 2e-56
Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%)
Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++
Sbjct: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
+ IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ +
Sbjct: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149
Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R +
Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209
Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264
+++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL
Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263
Query: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324
L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322
Query: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351
+ QFE + +P C+ D + QQL
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 216 bits (551), Expect = 2e-56
Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%)
Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++
Sbjct: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
+ IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ +
Sbjct: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149
Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R +
Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209
Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264
+++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL
Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263
Query: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324
L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322
Query: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351
+ QFE + +P C+ D + QQL
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 216 bits (551), Expect = 2e-56
Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%)
Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++
Sbjct: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
+ IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ +
Sbjct: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149
Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R +
Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209
Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264
+++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL
Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263
Query: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324
L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322
Query: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351
+ QFE + +P C+ D + QQL
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 31.6 bits (70), Expect = 1.2
Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 271 NLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADFSQF 330
NL EKE E+ +T++ + +EIY E + +S+ + V + QF
Sbjct: 1499 NLSEKETEI-----STIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQF 1553
Query: 331 EQIRKSPDCTFYCADSEKQQLEEKYRQEDQREREL 365
++ RK+ D +S+ +L + QE Q E ++
Sbjct: 1554 KEHRKAKDSALQSIESKMLELTNRL-QESQEEIQI 1587
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,676,353
Number of Sequences: 37866
Number of extensions: 508375
Number of successful extensions: 1902
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1838
Number of HSP's gapped (non-prelim): 56
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.