Guide to the Human Genome
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Search of human proteins with 25777638

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
         (375 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi...   747   0.0  
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi...   747   0.0  
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi...   747   0.0  
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ...   445   e-125
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [...   346   2e-95
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [...   346   2e-95
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H...   346   2e-95
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ...   346   2e-95
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [...   346   2e-95
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ...   285   4e-77
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis...   281   9e-76
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]    274   1e-73
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ...   272   3e-73
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ...   272   3e-73
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ...   272   3e-73
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]    266   2e-71
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]   266   2e-71
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]   258   8e-69
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]   256   3e-68
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi...   256   3e-68
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]    253   2e-67
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]    252   3e-67
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi...   242   3e-64
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [...   238   5e-63
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap...   237   1e-62
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]    227   2e-59
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]   216   2e-56
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi...   216   2e-56
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi...   216   2e-56
gi|71061468 centromere protein E [Homo sapiens]                        32   1.2  

>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
           sapiens]
          Length = 375

 Score =  747 bits (1929), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 1   MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60
           MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID
Sbjct: 1   MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60

Query: 61  MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120
           MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF
Sbjct: 61  MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120

Query: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180
           SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF
Sbjct: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180

Query: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240
           SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD
Sbjct: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240

Query: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300
           SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY
Sbjct: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300

Query: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360
           IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ
Sbjct: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360

Query: 361 RERELRTLLLQQSNV 375
           RERELRTLLLQQSNV
Sbjct: 361 RERELRTLLLQQSNV 375


>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
           sapiens]
          Length = 375

 Score =  747 bits (1929), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 1   MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60
           MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID
Sbjct: 1   MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60

Query: 61  MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120
           MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF
Sbjct: 61  MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120

Query: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180
           SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF
Sbjct: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180

Query: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240
           SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD
Sbjct: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240

Query: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300
           SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY
Sbjct: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300

Query: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360
           IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ
Sbjct: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360

Query: 361 RERELRTLLLQQSNV 375
           RERELRTLLLQQSNV
Sbjct: 361 RERELRTLLLQQSNV 375


>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
           sapiens]
          Length = 375

 Score =  747 bits (1929), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 1   MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60
           MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID
Sbjct: 1   MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60

Query: 61  MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120
           MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF
Sbjct: 61  MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120

Query: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180
           SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF
Sbjct: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180

Query: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240
           SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD
Sbjct: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240

Query: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300
           SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY
Sbjct: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300

Query: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360
           IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ
Sbjct: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360

Query: 361 RERELRTLLLQQSNV 375
           RERELRTLLLQQSNV
Sbjct: 361 RERELRTLLLQQSNV 375


>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
           member 10 [Homo sapiens]
          Length = 379

 Score =  445 bits (1144), Expect = e-125
 Identities = 231/363 (63%), Positives = 283/363 (77%), Gaps = 11/363 (3%)

Query: 19  GAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTW 78
           G G++  R RV++K G SNVR++ +     LYL+DLWTT IDM+WRYKL LF+ATF  TW
Sbjct: 22  GPGIR--RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTW 79

Query: 79  FLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEE 138
           FLFGV++Y +A  HGDL   +P +NHTPC+++V +LTGAFLFSLESQTTIGYG R I+EE
Sbjct: 80  FLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEE 139

Query: 139 CPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQ 198
           CP AI LL+AQLV+TT++EIFITGTFLAKIARPKKRAETI+FS  AV+   NGK CL+I+
Sbjct: 140 CPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIR 199

Query: 199 VANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVL 258
           VANMRKSLLI CQ++GKLLQTH TKEGE I LNQ  V F VD++S+SPFLILP+TFYHV+
Sbjct: 200 VANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVV 259

Query: 259 DETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLS 318
           DETSPL+DL P    E +FELV++L+ TVESTSA CQ RTSY+PEEI WG+EF P +SLS
Sbjct: 260 DETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLS 318

Query: 319 KNGKYVADFSQFEQIRK--SP----DCTFYCADSEKQQLEEKYRQEDQRERELRTLLLQQ 372
            +GKY+ADFS F+Q+ K  SP    D T    D EK +LEE  R  +Q E+E   L ++ 
Sbjct: 319 ASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEESLR--EQAEKEGSALSVRI 376

Query: 373 SNV 375
           SNV
Sbjct: 377 SNV 379


>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  346 bits (887), Expect = 2e-95
 Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%)

Query: 21  GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79
           G    R R++SK G  N+    V+     ++  D+WTTV+D+KWRYK+T+F   F+ +WF
Sbjct: 15  GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74

Query: 80  LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139
            FG+++YA+A+IH DL    P +NHTPC+  ++ LT AFLFSLE+Q TIGYG R +TE+C
Sbjct: 75  FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134

Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199
             AIFLL+ Q ++  +I  F+ G  LAKI+RPKKRA+TI FS  AVI+K+ GKLCL+I+V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194

Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259
           AN+RKSLLI   + GKLL+T VT EGE I+L+Q  + F VD+ +E+ F I P+T YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254

Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319
             SP   +  + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314

Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348
            GKY  DF  F +    ++P C   C  +EK
Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344


>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  346 bits (887), Expect = 2e-95
 Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%)

Query: 21  GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79
           G    R R++SK G  N+    V+     ++  D+WTTV+D+KWRYK+T+F   F+ +WF
Sbjct: 15  GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74

Query: 80  LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139
            FG+++YA+A+IH DL    P +NHTPC+  ++ LT AFLFSLE+Q TIGYG R +TE+C
Sbjct: 75  FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134

Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199
             AIFLL+ Q ++  +I  F+ G  LAKI+RPKKRA+TI FS  AVI+K+ GKLCL+I+V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194

Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259
           AN+RKSLLI   + GKLL+T VT EGE I+L+Q  + F VD+ +E+ F I P+T YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254

Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319
             SP   +  + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314

Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348
            GKY  DF  F +    ++P C   C  +EK
Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344


>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
           sapiens]
          Length = 391

 Score =  346 bits (887), Expect = 2e-95
 Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%)

Query: 21  GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79
           G    R R++SK G  N+    V+     ++  D+WTTV+D+KWRYK+T+F   F+ +WF
Sbjct: 34  GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 93

Query: 80  LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139
            FG+++YA+A+IH DL    P +NHTPC+  ++ LT AFLFSLE+Q TIGYG R +TE+C
Sbjct: 94  FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 153

Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199
             AIFLL+ Q ++  +I  F+ G  LAKI+RPKKRA+TI FS  AVI+K+ GKLCL+I+V
Sbjct: 154 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 213

Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259
           AN+RKSLLI   + GKLL+T VT EGE I+L+Q  + F VD+ +E+ F I P+T YHV+D
Sbjct: 214 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 273

Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319
             SP   +  + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K
Sbjct: 274 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 333

Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348
            GKY  DF  F +    ++P C   C  +EK
Sbjct: 334 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 363


>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  346 bits (887), Expect = 2e-95
 Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%)

Query: 21  GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79
           G    R R++SK G  N+    V+     ++  D+WTTV+D+KWRYK+T+F   F+ +WF
Sbjct: 15  GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74

Query: 80  LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139
            FG+++YA+A+IH DL    P +NHTPC+  ++ LT AFLFSLE+Q TIGYG R +TE+C
Sbjct: 75  FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134

Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199
             AIFLL+ Q ++  +I  F+ G  LAKI+RPKKRA+TI FS  AVI+K+ GKLCL+I+V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194

Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259
           AN+RKSLLI   + GKLL+T VT EGE I+L+Q  + F VD+ +E+ F I P+T YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254

Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319
             SP   +  + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314

Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348
            GKY  DF  F +    ++P C   C  +EK
Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344


>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  346 bits (887), Expect = 2e-95
 Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%)

Query: 21  GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79
           G    R R++SK G  N+    V+     ++  D+WTTV+D+KWRYK+T+F   F+ +WF
Sbjct: 15  GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74

Query: 80  LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139
            FG+++YA+A+IH DL    P +NHTPC+  ++ LT AFLFSLE+Q TIGYG R +TE+C
Sbjct: 75  FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134

Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199
             AIFLL+ Q ++  +I  F+ G  LAKI+RPKKRA+TI FS  AVI+K+ GKLCL+I+V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194

Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259
           AN+RKSLLI   + GKLL+T VT EGE I+L+Q  + F VD+ +E+ F I P+T YHV+D
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254

Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319
             SP   +  + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K
Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314

Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348
            GKY  DF  F +    ++P C   C  +EK
Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344


>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
           member 12 [Homo sapiens]
          Length = 433

 Score =  285 bits (730), Expect = 4e-77
 Identities = 142/333 (42%), Positives = 216/333 (64%), Gaps = 11/333 (3%)

Query: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
           R R + K+G  N+    +D     YL D++TT +D++WRY L +F+  F+ +W LFG+I+
Sbjct: 43  RNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIF 102

Query: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
           + IA  HGDLEP E     TPC+M+V     AFLFS+E+QTTIGYG+R +TEECP A+F+
Sbjct: 103 WVIAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFM 161

Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
           +VAQ ++  +I+ F+ G  +AK+ARPKKRA+T+ FSH AV+  ++GKLCL+ +V N+RKS
Sbjct: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221

Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
            +++  +  +L++  VT+EGE I L+Q  +    D   +  FL+ P+T  H +DE SPL 
Sbjct: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281

Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
            ++ Q+L+  +FE+VV+L   VE+T+   Q+R+SY+  EI WG  F PV+   KN +Y  
Sbjct: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340

Query: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
           D+S F    ++  +P C      S K  +E K+
Sbjct: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367


>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
           susceptibility ion channel [Homo sapiens]
          Length = 433

 Score =  281 bits (718), Expect = 9e-76
 Identities = 142/333 (42%), Positives = 214/333 (64%), Gaps = 11/333 (3%)

Query: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
           R R + K+G  N+    +D     YL D++TT +D++WRY L +F+  F+ +W LFGVI+
Sbjct: 43  RNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 102

Query: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
           + IA  HGDLEP E     TPC+M+V     AFLFS+E+QTTIGYG+R +TEEC  A+F+
Sbjct: 103 WVIAVAHGDLEPAEG-HGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFM 161

Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
           +VAQ ++  +I+ F+ G  +AK+ARPKKRA T+ FSH AV+  ++GKLCL+ +V N+RKS
Sbjct: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221

Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
            +++  +  +L++  VT+EGE I L+Q  +    D   +  FL+ P+T  H +DE SPL 
Sbjct: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281

Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
            ++ Q+L+  +FE+VV+L   VE+T+   Q+R+SY+  EI WG  F PV+   KN +Y  
Sbjct: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340

Query: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
           D+S F    ++  +P C      S K  +E K+
Sbjct: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367


>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
          Length = 427

 Score =  274 bits (700), Expect = 1e-73
 Identities = 139/330 (42%), Positives = 212/330 (64%), Gaps = 7/330 (2%)

Query: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
           R R + K GH NV+   V      YL D++TT +D++WR+ L +F   FV++W  FG ++
Sbjct: 44  RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103

Query: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
           + IA +HGDL+  +       C+ +V+S T AFLFS+E+QTTIGYG R +T+ECP A+F+
Sbjct: 104 WLIALLHGDLDASK---EGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM 160

Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
           +V Q ++  +I+ FI G  +AK+A+PKKR ET+ FSH AVI  ++GKLCL+ +V N+RKS
Sbjct: 161 VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKS 220

Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
            L++  +  +LL++ +T EGE I L+Q  +    DS  +  FL+ P+T  H +DE SPL 
Sbjct: 221 HLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLY 280

Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
           DL+ Q++   +FE+VV+L   VE+T+   Q R+SY+  EI WG  + PV+   K+  Y  
Sbjct: 281 DLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKH-YYKV 339

Query: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEKY 355
           D+S+F +  + P+ T  C  S +   E+KY
Sbjct: 340 DYSRFHKTYEVPN-TPLC--SARDLAEKKY 366


>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
           negative regulator Kir2.2v isoform 1 [Homo sapiens]
          Length = 432

 Score =  272 bits (696), Expect = 3e-73
 Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%)

Query: 28  RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
           R + K+G  N+    +D     YL D++TT +D++WRY L +F+  F+ +W LFGVI++ 
Sbjct: 45  RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104

Query: 88  IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147
           IA  HGDLEP E     TPC+M+V     AFLFS+++Q TI YG+R +TEECP A+F++V
Sbjct: 105 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 163

Query: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207
           AQ ++  +I  F+ G  +AK+ RPKKRA+T+ FSH AV+  ++GKLC + +V N+RKS +
Sbjct: 164 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 223

Query: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267
           ++  +  +L++  VTKEGE I L+Q  +    D   +  FL+ P+T  H +DE SPL  +
Sbjct: 224 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 283

Query: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327
           + Q+L+  +FE+V++L   VE+T+   Q+R+SY+  EI WG  F PV  L +  +Y  D+
Sbjct: 284 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 341

Query: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
             F    ++  +P C      S K  +E K+
Sbjct: 342 LHFHKTYEVPSTPRC------SAKDLVENKF 366


>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
           negative regulator Kir2.2v isoform 2 [Homo sapiens]
          Length = 534

 Score =  272 bits (696), Expect = 3e-73
 Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%)

Query: 28  RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
           R + K+G  N+    +D     YL D++TT +D++WRY L +F+  F+ +W LFGVI++ 
Sbjct: 147 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 206

Query: 88  IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147
           IA  HGDLEP E     TPC+M+V     AFLFS+++Q TI YG+R +TEECP A+F++V
Sbjct: 207 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 265

Query: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207
           AQ ++  +I  F+ G  +AK+ RPKKRA+T+ FSH AV+  ++GKLC + +V N+RKS +
Sbjct: 266 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 325

Query: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267
           ++  +  +L++  VTKEGE I L+Q  +    D   +  FL+ P+T  H +DE SPL  +
Sbjct: 326 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 385

Query: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327
           + Q+L+  +FE+V++L   VE+T+   Q+R+SY+  EI WG  F PV  L +  +Y  D+
Sbjct: 386 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 443

Query: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
             F    ++  +P C      S K  +E K+
Sbjct: 444 LHFHKTYEVPSTPRC------SAKDLVENKF 468


>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
           sapiens]
          Length = 432

 Score =  272 bits (696), Expect = 3e-73
 Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%)

Query: 28  RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
           R + K+G  N+    +D     YL D++TT +D++WRY L +F+  F+ +W LFGVI++ 
Sbjct: 45  RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104

Query: 88  IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147
           IA  HGDLEP E     TPC+M+V     AFLFS+++Q TI YG+R +TEECP A+F++V
Sbjct: 105 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 163

Query: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207
           AQ ++  +I  F+ G  +AK+ RPKKRA+T+ FSH AV+  ++GKLC + +V N+RKS +
Sbjct: 164 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 223

Query: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267
           ++  +  +L++  VTKEGE I L+Q  +    D   +  FL+ P+T  H +DE SPL  +
Sbjct: 224 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 283

Query: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327
           + Q+L+  +FE+V++L   VE+T+   Q+R+SY+  EI WG  F PV  L +  +Y  D+
Sbjct: 284 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 341

Query: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355
             F    ++  +P C      S K  +E K+
Sbjct: 342 LHFHKTYEVPSTPRC------SAKDLVENKF 366


>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
          Length = 445

 Score =  266 bits (681), Expect = 2e-71
 Identities = 134/336 (39%), Positives = 210/336 (62%), Gaps = 19/336 (5%)

Query: 23  KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
           +  R R + K+G  NV    +      Y+ D++TT +D +WRY L +F+A F+++W  FG
Sbjct: 15  RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74

Query: 83  VIYYAIAFIHGDLE--PGEPISNHT-------------PCIMKVDSLTGAFLFSLESQTT 127
           ++++ IAF HGDLE  PG P +                PCIM V+   GAFLFS+E+QTT
Sbjct: 75  LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134

Query: 128 IGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVIT 187
           IGYG R +TEECP A+  +V Q ++  +I+ F+ GT +AK+ARPKKRA+T+ FSH AVI+
Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194

Query: 188 KQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPF 247
            ++GKLCL+ +V N+RKS +++  +  +L++ ++T+EGE + L+Q  +    D   +  F
Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254

Query: 248 LILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYW 307
           L+ P+   H +DE SPL  +  + L+ ++FE+VV+L   VE+T+   Q+R+SY+  EI W
Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314

Query: 308 GFEFVPVVSLSKNGKYVADFSQFE---QIRKSPDCT 340
           G  F PVV   +   Y  D+S+F    ++  +P C+
Sbjct: 315 GHRFEPVV-FEEKSHYKVDYSRFHKTYEVAGTPCCS 349


>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
          Length = 445

 Score =  266 bits (681), Expect = 2e-71
 Identities = 134/336 (39%), Positives = 210/336 (62%), Gaps = 19/336 (5%)

Query: 23  KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
           +  R R + K+G  NV    +      Y+ D++TT +D +WRY L +F+A F+++W  FG
Sbjct: 15  RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74

Query: 83  VIYYAIAFIHGDLE--PGEPISNHT-------------PCIMKVDSLTGAFLFSLESQTT 127
           ++++ IAF HGDLE  PG P +                PCIM V+   GAFLFS+E+QTT
Sbjct: 75  LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134

Query: 128 IGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVIT 187
           IGYG R +TEECP A+  +V Q ++  +I+ F+ GT +AK+ARPKKRA+T+ FSH AVI+
Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194

Query: 188 KQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPF 247
            ++GKLCL+ +V N+RKS +++  +  +L++ ++T+EGE + L+Q  +    D   +  F
Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254

Query: 248 LILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYW 307
           L+ P+   H +DE SPL  +  + L+ ++FE+VV+L   VE+T+   Q+R+SY+  EI W
Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314

Query: 308 GFEFVPVVSLSKNGKYVADFSQFE---QIRKSPDCT 340
           G  F PVV   +   Y  D+S+F    ++  +P C+
Sbjct: 315 GHRFEPVV-FEEKSHYKVDYSRFHKTYEVAGTPCCS 349


>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
          Length = 419

 Score =  258 bits (658), Expect = 8e-69
 Identities = 129/320 (40%), Positives = 198/320 (61%), Gaps = 7/320 (2%)

Query: 23  KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
           K  R R M KSG  NV    V   Y  YL DL+TT++D+KWR+ L +F   + +TW  FG
Sbjct: 47  KKPRQRYMEKSGKCNVHHGNVQETYR-YLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105

Query: 83  VIYYAIAFIHGDLEP-GEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPH 141
            I++ IA+I GDL+  G+      PC+  +     AFLFS+E++TTIGYG R ITE+CP 
Sbjct: 106 FIWWLIAYIRGDLDHVGD--QEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPE 163

Query: 142 AIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVAN 201
            I LL+ Q ++ +++  F+ G    KI++PKKRAET+ FS+ AVI+ ++ KLCL+ +V +
Sbjct: 164 GIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGD 223

Query: 202 MRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDET 261
           +R S +++  +  KL+++  TKEGE I LNQ  +    D+  +  FL+ P+   H +++ 
Sbjct: 224 LRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQK 283

Query: 262 SPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321
           SP  +++   L ++EFE+VV+L   VE+T   CQ+R+SY+  E+ WG  F PV++L K G
Sbjct: 284 SPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-G 342

Query: 322 KYVADFSQFEQI--RKSPDC 339
            Y  D++ F       +P C
Sbjct: 343 FYEVDYNTFHDTYETNTPSC 362


>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
          Length = 436

 Score =  256 bits (653), Expect = 3e-68
 Identities = 133/329 (40%), Positives = 199/329 (60%), Gaps = 5/329 (1%)

Query: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
           R R + K GH NVR   + G    YL DL+TT +D++WR+   LF+ +F+ +W LFG+ +
Sbjct: 49  RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108

Query: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
           + IA +HGDL    P +   PC   V S   AFLF+LE+QT+IGYGVRS+TEECP A+  
Sbjct: 109 WLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAA 165

Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
           +V Q +   +++ F+ G  +AK+A+PKKR ET+ FS  AV+  ++ +LCL+ +V N+R+S
Sbjct: 166 VVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRS 225

Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
            L++  +  +LLQ  VT EGE I L+   V    D  ++  FL+ P+T  H +D  SPL 
Sbjct: 226 HLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLY 285

Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
           +L    L   +FELVV+L   VE+T+   Q R+SY+P E+ WG  F PV+   +  +Y  
Sbjct: 286 ELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL-FQRGSQYEV 344

Query: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEK 354
           D+  F +  + P  T  C+  E  +  E+
Sbjct: 345 DYRHFHRTYEVPG-TPVCSAKELDERAEQ 372


>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
           sapiens]
          Length = 436

 Score =  256 bits (653), Expect = 3e-68
 Identities = 133/329 (40%), Positives = 199/329 (60%), Gaps = 5/329 (1%)

Query: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
           R R + K GH NVR   + G    YL DL+TT +D++WR+   LF+ +F+ +W LFG+ +
Sbjct: 49  RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108

Query: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
           + IA +HGDL    P +   PC   V S   AFLF+LE+QT+IGYGVRS+TEECP A+  
Sbjct: 109 WLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAA 165

Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
           +V Q +   +++ F+ G  +AK+A+PKKR ET+ FS  AV+  ++ +LCL+ +V N+R+S
Sbjct: 166 VVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRS 225

Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
            L++  +  +LLQ  VT EGE I L+   V    D  ++  FL+ P+T  H +D  SPL 
Sbjct: 226 HLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLY 285

Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
           +L    L   +FELVV+L   VE+T+   Q R+SY+P E+ WG  F PV+   +  +Y  
Sbjct: 286 ELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL-FQRGSQYEV 344

Query: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEK 354
           D+  F +  + P  T  C+  E  +  E+
Sbjct: 345 DYRHFHRTYEVPG-TPVCSAKELDERAEQ 372


>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
          Length = 501

 Score =  253 bits (646), Expect = 2e-67
 Identities = 123/329 (37%), Positives = 201/329 (61%), Gaps = 2/329 (0%)

Query: 23  KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
           K  R R + K+G  NV+   +      YL DL+TT++D+KWR+ L +F  T+ + W    
Sbjct: 40  KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99

Query: 83  VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
            +++ IA+  GDL     + N+TPC+  V +   AFLF +E++ TIGYG R IT++CP  
Sbjct: 100 SMWWVIAYTRGDLNKAH-VGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEG 158

Query: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
           I L + Q ++ ++++ F+ G    K+++PKKRAET+ FS  AVI+ ++GKL L+ +V N+
Sbjct: 159 IILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNL 218

Query: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
           R S ++  Q+  KLL++  T EGE + L+Q  +     + ++  FL+ P+T  HV+D  S
Sbjct: 219 RNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKS 278

Query: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322
           P  DL+ ++++ ++FE+VV+L   VE+T   CQ+RTSY  +E+ WG  F PV+SL + G 
Sbjct: 279 PFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEGF 337

Query: 323 YVADFSQFEQIRKSPDCTFYCADSEKQQL 351
           +  D+SQF    + P   +   + E+  L
Sbjct: 338 FKVDYSQFHATFEVPTPPYSVKEQEEMLL 366


>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
          Length = 423

 Score =  252 bits (644), Expect = 3e-67
 Identities = 125/320 (39%), Positives = 200/320 (62%), Gaps = 3/320 (0%)

Query: 13  LVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAA 72
           L +H +    K    R + K G  NV    V   Y  YL D++TT++D+KWR+ L +F  
Sbjct: 40  LPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYR-YLTDIFTTLVDLKWRFNLLIFVM 98

Query: 73  TFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGV 132
            + +TW  FG+I++ IA+I GD++  E  S  TPC+  ++    AFLFS+E++TTIGYG 
Sbjct: 99  VYTVTWLFFGMIWWLIAYIRGDMDHIEDPS-WTPCVTNLNGFVSAFLFSIETETTIGYGY 157

Query: 133 RSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGK 192
           R IT++CP  I LL+ Q V+ +++  F+ G    KI++PKKRAET+ FS  AVI+ ++GK
Sbjct: 158 RVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGK 217

Query: 193 LCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPM 252
           LCL+ +V ++R S +++  +  KL+++  T EGE I LNQ  +     +  +  FL+ P+
Sbjct: 218 LCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPL 277

Query: 253 TFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFV 312
              H +++ SP  +++   L ++E E+VV+L   VE+T   CQ+R+SYI  EI WG+ F 
Sbjct: 278 IISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFT 337

Query: 313 PVVSLSKNGKYVADFSQFEQ 332
           PV++L ++G Y  D++ F +
Sbjct: 338 PVLTL-EDGFYEVDYNSFHE 356


>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
           sapiens]
          Length = 390

 Score =  242 bits (618), Expect = 3e-64
 Identities = 126/333 (37%), Positives = 201/333 (60%), Gaps = 7/333 (2%)

Query: 23  KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
           +  R R +SK G+ NV    +      +LQD++TT++D+KW + L +F  +F+ +W LF 
Sbjct: 29  RQRRARFVSKKGNCNVAHKNIRE-QGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87

Query: 83  VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
           + ++ IAF HGDL P E  +   PC+  + S + AFLFS+E Q TIG+G R +TEECP A
Sbjct: 88  MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145

Query: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
           I +L+ Q ++  +I   + G    K A+  +RAET+ FS  AVI  ++G+LC +++V ++
Sbjct: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205

Query: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
           RKS++I   +  ++++   + EGE + L+Q  +         S FL+ P+  YHV+D  S
Sbjct: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265

Query: 263 PLRDLTPQNL-KEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321
           PL DL P +L   ++ E++V+L   VE+T    Q+RTSY+ +EI WG  FVP+V+  ++G
Sbjct: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVA-EEDG 324

Query: 322 KYVADFSQFEQIRK--SPDCTFYCADSEKQQLE 352
           +Y  D+S+F    K  +P CT    D +   LE
Sbjct: 325 RYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLE 357


>gi|25121970 potassium inwardly-rectifying channel subfamily J9
           [Homo sapiens]
          Length = 393

 Score =  238 bits (608), Expect = 5e-63
 Identities = 117/315 (37%), Positives = 193/315 (61%), Gaps = 3/315 (0%)

Query: 23  KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82
           +  R R + K G  NV+   V   Y  YL DL+TT++D++WR  L  F   + +TW  FG
Sbjct: 18  RRGRQRYVEKDGRCNVQQGNVRETYR-YLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76

Query: 83  VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142
            I++ IA+  GDLE  E  +  TPC+  ++    AFLFS+E++TTIGYG R IT++CP  
Sbjct: 77  AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135

Query: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202
           I LL+ Q ++ +++  F+ G    KI++P KRA T+ FS  AV++ ++G+LCL+ +V ++
Sbjct: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195

Query: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262
           R S +++  +  KL+++  T EGE I L+Q  +    D+  +  FL+ P+   H +D  S
Sbjct: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255

Query: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322
           P  + + + L+  +FE+VV+L   VE+T   CQ+R+SY+ +E+ WG  F  V++L ++G 
Sbjct: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTL-EDGF 314

Query: 323 YVADFSQFEQIRKSP 337
           Y  D++ F +  + P
Sbjct: 315 YEVDYASFHETFEVP 329


>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
           sapiens]
          Length = 360

 Score =  237 bits (604), Expect = 1e-62
 Identities = 135/326 (41%), Positives = 194/326 (59%), Gaps = 20/326 (6%)

Query: 28  RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
           R+++K GHS +++D      L YL+D W  ++DM+WR+ + +F+A+FV+ W +F V++Y 
Sbjct: 19  RMVTKDGHSTLQMDGAQR-GLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77

Query: 88  IAFIHGDLEPGE--PISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
           +A ++GDLE     P  NHT C+  + S T AF FSLE+Q TIGYG    + +CP AI L
Sbjct: 78  LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137

Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
           L  Q+++  ++E FITG F+AKIARPK RA +I+F+  AV+   +GK  L+ QVAN R S
Sbjct: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197

Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD--SSSESPFLILPMTFYHVLDETSP 263
            L   ++S  L Q     E E   L Q +V FH+D  SS E PF I P+T+YH +  +SP
Sbjct: 198 PLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252

Query: 264 LRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKY 323
           L  L  Q+     FELVV L+A  E T  +CQ RTSY+P EI     F  +++    G+Y
Sbjct: 253 LATLL-QHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311

Query: 324 VADFSQFEQ---------IRKSPDCT 340
                 F++         + KSP+ T
Sbjct: 312 QIKMENFDKTVPEFPTPLVSKSPNRT 337


>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
          Length = 424

 Score =  227 bits (578), Expect = 2e-59
 Identities = 123/329 (37%), Positives = 196/329 (59%), Gaps = 21/329 (6%)

Query: 26  RPRVMSKSG-----HSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFL 80
           + R ++KSG     H N+R          +LQD++TT++D+KWR+ L +F  +F+ +W L
Sbjct: 33  KARFIAKSGACNLAHKNIREQG------RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLL 86

Query: 81  FGVIYYAIAFIHGDL-----EPGEPISN--HTPCIMKVDSLTGAFLFSLESQTTIGYGVR 133
           F ++++ +AF HGD+     + G   S    T C+  V S T AFLFS+E Q TIG+G R
Sbjct: 87  FAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGR 146

Query: 134 SITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKL 193
            +TEECP AI +L+ Q ++  +I   + G    K A+  +RAET+ FS  AVI  +NGKL
Sbjct: 147 MMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKL 206

Query: 194 CLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMT 253
           C + +V ++RKS++I   +  ++++   T EGE + ++Q  +       S + FL+ P+ 
Sbjct: 207 CFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLI 266

Query: 254 FYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVP 313
             HV+D+ SPL D++  +L  ++ E++V+L   VE+T    Q+RTSYI EEI WG  FV 
Sbjct: 267 ICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVS 326

Query: 314 VVSLSKNGKYVADFSQFEQIRK--SPDCT 340
           +V+  + G Y  D+S+F    K  +P C+
Sbjct: 327 IVT-EEEGVYSVDYSKFGNTVKVAAPRCS 354


>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
          Length = 418

 Score =  216 bits (551), Expect = 2e-56
 Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%)

Query: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
           R R++ K G  NV    + G +  Y+ D++TT++D KWR+   +F+ +++++W +FG ++
Sbjct: 33  RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92

Query: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
           + IAF HGDL     I   TPC+  V S TGAFLFSLE+QTTIGYG R +TEEC  A+ +
Sbjct: 93  WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149

Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
           ++ Q +++ +I  FI G  LAK+A  +KRA+TI+FS+ A+I  ++GKLCL+ ++ + R +
Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209

Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264
            +++  +  +LL+     EG      + T+ F  +   ++   L+ P+T  H +D  SPL
Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263

Query: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324
             L  + + +  FE++V    T +ST    QSR+SY+P EI WG  F  V+ + K   Y 
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322

Query: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351
            +  QFE   +  +P C+    D + QQL
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351


>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
           sapiens]
          Length = 418

 Score =  216 bits (551), Expect = 2e-56
 Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%)

Query: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
           R R++ K G  NV    + G +  Y+ D++TT++D KWR+   +F+ +++++W +FG ++
Sbjct: 33  RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92

Query: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
           + IAF HGDL     I   TPC+  V S TGAFLFSLE+QTTIGYG R +TEEC  A+ +
Sbjct: 93  WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149

Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
           ++ Q +++ +I  FI G  LAK+A  +KRA+TI+FS+ A+I  ++GKLCL+ ++ + R +
Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209

Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264
            +++  +  +LL+     EG      + T+ F  +   ++   L+ P+T  H +D  SPL
Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263

Query: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324
             L  + + +  FE++V    T +ST    QSR+SY+P EI WG  F  V+ + K   Y 
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322

Query: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351
            +  QFE   +  +P C+    D + QQL
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351


>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
           sapiens]
          Length = 418

 Score =  216 bits (551), Expect = 2e-56
 Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%)

Query: 26  RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
           R R++ K G  NV    + G +  Y+ D++TT++D KWR+   +F+ +++++W +FG ++
Sbjct: 33  RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92

Query: 86  YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
           + IAF HGDL     I   TPC+  V S TGAFLFSLE+QTTIGYG R +TEEC  A+ +
Sbjct: 93  WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149

Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
           ++ Q +++ +I  FI G  LAK+A  +KRA+TI+FS+ A+I  ++GKLCL+ ++ + R +
Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209

Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264
            +++  +  +LL+     EG      + T+ F  +   ++   L+ P+T  H +D  SPL
Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263

Query: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324
             L  + + +  FE++V    T +ST    QSR+SY+P EI WG  F  V+ + K   Y 
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322

Query: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351
            +  QFE   +  +P C+    D + QQL
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 6/95 (6%)

Query: 271  NLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADFSQF 330
            NL EKE E+     +T++        +     +EIY   E   +  +S+  + V +  QF
Sbjct: 1499 NLSEKETEI-----STIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQF 1553

Query: 331  EQIRKSPDCTFYCADSEKQQLEEKYRQEDQREREL 365
            ++ RK+ D      +S+  +L  +  QE Q E ++
Sbjct: 1554 KEHRKAKDSALQSIESKMLELTNRL-QESQEEIQI 1587


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,676,353
Number of Sequences: 37866
Number of extensions: 508375
Number of successful extensions: 1902
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1838
Number of HSP's gapped (non-prelim): 56
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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