BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapiens] (418 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 853 0.0 gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 853 0.0 gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 853 0.0 gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 322 5e-88 gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 322 5e-88 gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 321 9e-88 gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 315 6e-86 gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 312 3e-85 gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 304 1e-82 gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 304 1e-82 gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 303 1e-82 gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 303 1e-82 gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 303 1e-82 gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 286 2e-77 gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 284 1e-76 gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 278 5e-75 gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 268 5e-72 gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 266 2e-71 gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 257 1e-68 gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 250 2e-66 gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 250 2e-66 gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 250 2e-66 gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 250 2e-66 gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 250 2e-66 gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 226 3e-59 gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 216 2e-56 gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 216 2e-56 gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 216 2e-56 gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 156 3e-38 gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec... 29 6.9 >gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] Length = 418 Score = 853 bits (2204), Expect = 0.0 Identities = 418/418 (100%), Positives = 418/418 (100%) Query: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD Sbjct: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60 Query: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG Sbjct: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120 Query: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ Sbjct: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180 Query: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL Sbjct: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240 Query: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV Sbjct: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300 Query: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR Sbjct: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360 Query: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM Sbjct: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418 >gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapiens] Length = 418 Score = 853 bits (2204), Expect = 0.0 Identities = 418/418 (100%), Positives = 418/418 (100%) Query: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD Sbjct: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60 Query: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG Sbjct: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120 Query: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ Sbjct: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180 Query: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL Sbjct: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240 Query: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV Sbjct: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300 Query: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR Sbjct: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360 Query: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM Sbjct: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418 >gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapiens] Length = 418 Score = 853 bits (2204), Expect = 0.0 Identities = 418/418 (100%), Positives = 418/418 (100%) Query: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD Sbjct: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60 Query: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG Sbjct: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120 Query: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ Sbjct: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180 Query: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL Sbjct: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240 Query: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV Sbjct: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300 Query: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR Sbjct: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360 Query: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM Sbjct: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418 >gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] Length = 445 Score = 322 bits (824), Expect = 5e-88 Identities = 162/354 (45%), Positives = 239/354 (67%), Gaps = 26/354 (7%) Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88 +R+ R R + K+G CNVYF ++ + Y+ DIFTT VDT+WR+M +IFS ++++SWL F Sbjct: 14 RRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFF 73 Query: 89 GSVFWLIAFHHGDLLNDPDIT------------------PCVDNVHSFTGAFLFSLETQT 130 G +FW IAF HGDL P + PC+ +V+ F GAFLFS+ETQT Sbjct: 74 GLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQT 133 Query: 131 TIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALI 190 TIGYG+RCVTEEC +AV+ V++QSI+ C+I++F+IG +AKMA +KRAQT+ FS+ A+I Sbjct: 134 TIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVI 193 Query: 191 GMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLK----LVNDQI 245 +RDGKLCLMWR+G+ R +H+VE VRAQL++ EG + + +DL + D+I Sbjct: 194 SVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRI 253 Query: 246 ILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREIL 305 LV+P+ IVHEID +SPLY + ++ + ++FEI+V ++T + Q+RSSY+ EIL Sbjct: 254 FLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313 Query: 306 WGHRFNDVLEVKRKYYKVNCLQFEGSVEVY-APFCSAKQLDWKDQQLHIEKAPP 358 WGHRF V+ ++ +YKV+ +F + EV P CSA++L ++ ++ + APP Sbjct: 314 WGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSAREL--QESKITVLPAPP 365 >gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] Length = 445 Score = 322 bits (824), Expect = 5e-88 Identities = 162/354 (45%), Positives = 239/354 (67%), Gaps = 26/354 (7%) Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88 +R+ R R + K+G CNVYF ++ + Y+ DIFTT VDT+WR+M +IFS ++++SWL F Sbjct: 14 RRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFF 73 Query: 89 GSVFWLIAFHHGDLLNDPDIT------------------PCVDNVHSFTGAFLFSLETQT 130 G +FW IAF HGDL P + PC+ +V+ F GAFLFS+ETQT Sbjct: 74 GLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQT 133 Query: 131 TIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALI 190 TIGYG+RCVTEEC +AV+ V++QSI+ C+I++F+IG +AKMA +KRAQT+ FS+ A+I Sbjct: 134 TIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVI 193 Query: 191 GMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLK----LVNDQI 245 +RDGKLCLMWR+G+ R +H+VE VRAQL++ EG + + +DL + D+I Sbjct: 194 SVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRI 253 Query: 246 ILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREIL 305 LV+P+ IVHEID +SPLY + ++ + ++FEI+V ++T + Q+RSSY+ EIL Sbjct: 254 FLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313 Query: 306 WGHRFNDVLEVKRKYYKVNCLQFEGSVEVY-APFCSAKQLDWKDQQLHIEKAPP 358 WGHRF V+ ++ +YKV+ +F + EV P CSA++L ++ ++ + APP Sbjct: 314 WGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSAREL--QESKITVLPAPP 365 >gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] Length = 427 Score = 321 bits (822), Expect = 9e-88 Identities = 166/322 (51%), Positives = 222/322 (68%), Gaps = 6/322 (1%) Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88 +++ R R + KDG CNV F ++ + Y+ DIFTT VD +WR M VIF L+++LSWL F Sbjct: 40 RQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFF 99 Query: 89 GSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVL 148 G VFWLIA HGDL + CV V+SFT AFLFS+ETQTTIGYG+RCVT+EC +AV Sbjct: 100 GCVFWLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVF 159 Query: 149 MVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRP 208 MV+ QSI+ CII+ FIIGA +AKMA +KR +T+ FS+ A+I MRDGKLCLMWR+G+ R Sbjct: 160 MVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRK 219 Query: 209 NHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEIDHESPL 263 +H+VE VRAQLL+ SEG + + D+ + D+I LV+P+TIVHEID +SPL Sbjct: 220 SHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPL 279 Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKV 323 Y L ++ + +FEI+V ++T + Q RSSY+ EILWGHR+ VL ++ YYKV Sbjct: 280 YDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKV 339 Query: 324 NCLQFEGSVEV-YAPFCSAKQL 344 + +F + EV P CSA+ L Sbjct: 340 DYSRFHKTYEVPNTPLCSARDL 361 >gi|23110982 potassium inwardly-rectifying channel, subfamily J, member 12 [Homo sapiens] Length = 433 Score = 315 bits (806), Expect = 6e-86 Identities = 163/325 (50%), Positives = 224/325 (68%), Gaps = 10/325 (3%) Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88 +RR R R + K+G CN+ F ++ + Y+ D+FTT VD +WR+M +IFSL+++ SWL+F Sbjct: 39 RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98 Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 G +FW+IA HGDL TPCV VH F AFLFS+ETQTTIGYG RCVTEEC VA Sbjct: 99 GIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVA 158 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 V MV+ QSI+ CII++F+IGA +AKMA +KRAQT+ FS+ A++ +RDGKLCLMWR+G+ Sbjct: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNL 218 Query: 207 RPNHVVEGTVRAQLL--RYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHE 260 R +H+VE VRAQL+ R TE+ E + + D+ + D+I LV+P+TI+HEID Sbjct: 219 RKSHIVEAHVRAQLIKPRVTEEGE-YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277 Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY 320 SPL+ + R+ + D+FEI+V ++T + Q+RSSY+ EILWGHRF VL ++ Sbjct: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337 Query: 321 YKVNCLQFEGSVEV-YAPFCSAKQL 344 YK++ F + EV P CSAK L Sbjct: 338 YKIDYSHFHKTYEVPSTPRCSAKDL 362 >gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis susceptibility ion channel [Homo sapiens] Length = 433 Score = 312 bits (800), Expect = 3e-85 Identities = 162/325 (49%), Positives = 223/325 (68%), Gaps = 10/325 (3%) Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88 +RR R R + K+G CN+ F ++ + Y+ D+FTT VD +WR+M +IFSL+++ SWL+F Sbjct: 39 RRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98 Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 G +FW+IA HGDL TPCV VH F AFLFS+ETQTTIGYG RCVTEEC VA Sbjct: 99 GVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVA 158 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 V MV+ QSI+ CII++F+IGA +AKMA +KRA T+ FS+ A++ +RDGKLCLMWR+G+ Sbjct: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNL 218 Query: 207 RPNHVVEGTVRAQLL--RYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHE 260 R +H+VE VRAQL+ R TE+ E + + D+ + D+I LV+P+TI+HEID Sbjct: 219 RKSHIVEAHVRAQLIKPRVTEEGE-YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277 Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY 320 SPL+ + R+ + D+FEI+V ++T + Q+RSSY+ EILWGHRF VL ++ Sbjct: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337 Query: 321 YKVNCLQFEGSVEV-YAPFCSAKQL 344 YK++ F + EV P CSAK L Sbjct: 338 YKIDYSHFHKTYEVPSTPRCSAKDL 362 >gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] Length = 436 Score = 304 bits (778), Expect = 1e-82 Identities = 158/338 (46%), Positives = 220/338 (65%), Gaps = 6/338 (1%) Query: 19 GYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFS 78 G+ P + + R R R + KDG CNV F ++ G+ Y+ D+FTT VD +WR M ++FS Sbjct: 35 GWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFS 94 Query: 79 LSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138 S++ SWL+FG FWLIA HGDL P PC +V SF AFLF+LETQT+IGYG R Sbjct: 95 CSFLASWLLFGLAFWLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRS 154 Query: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198 VTEEC AV V+LQ I C+++ F++GA +AKMA +KR +T+ FS A++ +RD +LC Sbjct: 155 VTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLC 214 Query: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253 LMWR+G+ R +H+VE VRAQLL+ EG + + +D+ + D+I LV+P+TI Sbjct: 215 LMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITI 274 Query: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313 VHEID SPLY L R +A+ +FE++V ++T + Q RSSY+P E+LWGHRF V Sbjct: 275 VHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPV 334 Query: 314 LEVKRKYYKVNCLQFEGSVEV-YAPFCSAKQLDWKDQQ 350 L + Y+V+ F + EV P CSAK+LD + +Q Sbjct: 335 LFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQ 372 >gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapiens] Length = 436 Score = 304 bits (778), Expect = 1e-82 Identities = 158/338 (46%), Positives = 220/338 (65%), Gaps = 6/338 (1%) Query: 19 GYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFS 78 G+ P + + R R R + KDG CNV F ++ G+ Y+ D+FTT VD +WR M ++FS Sbjct: 35 GWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFS 94 Query: 79 LSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138 S++ SWL+FG FWLIA HGDL P PC +V SF AFLF+LETQT+IGYG R Sbjct: 95 CSFLASWLLFGLAFWLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRS 154 Query: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198 VTEEC AV V+LQ I C+++ F++GA +AKMA +KR +T+ FS A++ +RD +LC Sbjct: 155 VTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLC 214 Query: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253 LMWR+G+ R +H+VE VRAQLL+ EG + + +D+ + D+I LV+P+TI Sbjct: 215 LMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITI 274 Query: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313 VHEID SPLY L R +A+ +FE++V ++T + Q RSSY+P E+LWGHRF V Sbjct: 275 VHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPV 334 Query: 314 LEVKRKYYKVNCLQFEGSVEV-YAPFCSAKQLDWKDQQ 350 L + Y+V+ F + EV P CSAK+LD + +Q Sbjct: 335 LFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQ 372 >gi|239757993 PREDICTED: similar to inward rectifying K+ channel negative regulator Kir2.2v isoform 1 [Homo sapiens] Length = 432 Score = 303 bits (777), Expect = 1e-82 Identities = 156/324 (48%), Positives = 217/324 (66%), Gaps = 9/324 (2%) Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88 +RR R + K+G CN+ F ++ + Y+ DIFTT VD +WR+M +IFSL+++ SWL+F Sbjct: 39 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 98 Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 G +FW+IA HGDL TPCV VH F AFLFS++TQ TI YG RCVTEEC VA Sbjct: 99 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 158 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 V MV+ QSI+ CIIN+F+IGA +AKM +KRAQT+ FS+ A++ +RDGKLC MWR+G+ Sbjct: 159 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 218 Query: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKLVNDQ----IILVTPVTIVHEIDHES 261 R +H+VE VRAQL++ EG + + D+ + D+ LV+P+TI+HEID S Sbjct: 219 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 278 Query: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321 PL+ + R+ + D+FEI++ ++T + Q+RSSY+ EILWGHRF VL ++ Y Sbjct: 279 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 337 Query: 322 KVNCLQFEGSVEV-YAPFCSAKQL 344 K++ L F + EV P CSAK L Sbjct: 338 KIDYLHFHKTYEVPSTPRCSAKDL 361 >gi|239757991 PREDICTED: similar to inward rectifying K+ channel negative regulator Kir2.2v isoform 2 [Homo sapiens] Length = 534 Score = 303 bits (777), Expect = 1e-82 Identities = 156/324 (48%), Positives = 217/324 (66%), Gaps = 9/324 (2%) Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88 +RR R + K+G CN+ F ++ + Y+ DIFTT VD +WR+M +IFSL+++ SWL+F Sbjct: 141 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 200 Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 G +FW+IA HGDL TPCV VH F AFLFS++TQ TI YG RCVTEEC VA Sbjct: 201 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 260 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 V MV+ QSI+ CIIN+F+IGA +AKM +KRAQT+ FS+ A++ +RDGKLC MWR+G+ Sbjct: 261 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 320 Query: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKLVNDQ----IILVTPVTIVHEIDHES 261 R +H+VE VRAQL++ EG + + D+ + D+ LV+P+TI+HEID S Sbjct: 321 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 380 Query: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321 PL+ + R+ + D+FEI++ ++T + Q+RSSY+ EILWGHRF VL ++ Y Sbjct: 381 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 439 Query: 322 KVNCLQFEGSVEV-YAPFCSAKQL 344 K++ L F + EV P CSAK L Sbjct: 440 KIDYLHFHKTYEVPSTPRCSAKDL 463 >gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo sapiens] Length = 432 Score = 303 bits (777), Expect = 1e-82 Identities = 156/324 (48%), Positives = 217/324 (66%), Gaps = 9/324 (2%) Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88 +RR R + K+G CN+ F ++ + Y+ DIFTT VD +WR+M +IFSL+++ SWL+F Sbjct: 39 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 98 Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 G +FW+IA HGDL TPCV VH F AFLFS++TQ TI YG RCVTEEC VA Sbjct: 99 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 158 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 V MV+ QSI+ CIIN+F+IGA +AKM +KRAQT+ FS+ A++ +RDGKLC MWR+G+ Sbjct: 159 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 218 Query: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKLVNDQ----IILVTPVTIVHEIDHES 261 R +H+VE VRAQL++ EG + + D+ + D+ LV+P+TI+HEID S Sbjct: 219 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 278 Query: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321 PL+ + R+ + D+FEI++ ++T + Q+RSSY+ EILWGHRF VL ++ Y Sbjct: 279 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 337 Query: 322 KVNCLQFEGSVEV-YAPFCSAKQL 344 K++ L F + EV P CSAK L Sbjct: 338 KIDYLHFHKTYEVPSTPRCSAKDL 361 >gi|25121970 potassium inwardly-rectifying channel subfamily J9 [Homo sapiens] Length = 393 Score = 286 bits (733), Expect = 2e-77 Identities = 141/323 (43%), Positives = 219/323 (67%), Gaps = 8/323 (2%) Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88 +RR R+R + KDG CNV ++ E Y+ D+FTTLVD +WR + F L+Y L+WL F Sbjct: 17 RRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75 Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 G+++WLIA+ GDL L D TPCV+N++ F AFLFS+ET+TTIGYG+R +T++C Sbjct: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 +++++LQ+IL ++N F++G K++ KRA T+ FS A++ +RDG+LCLM+R+GD Sbjct: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195 Query: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEIDHES 261 R +H+VE ++RA+L+R + EG + + DL + +D++ LV+P+ I HEID S Sbjct: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255 Query: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321 P + R+A+ +D+FEI+V ++TG + Q+RSSY+ E+LWGHRF VL ++ +Y Sbjct: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315 Query: 322 KVNCLQFEGSVEVYAPFCSAKQL 344 +V+ F + EV P CSA++L Sbjct: 316 EVDYASFHETFEVPTPSCSAREL 338 >gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] Length = 423 Score = 284 bits (726), Expect = 1e-76 Identities = 140/331 (42%), Positives = 221/331 (66%), Gaps = 9/331 (2%) Query: 22 PEHIIAEK-RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLS 80 P HI ++ +R +R + KDG CNV+ ++ E Y+ DIFTTLVD KWR +IF + Sbjct: 41 PRHISRDRTKRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMV 99 Query: 81 YILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138 Y ++WL FG ++WLIA+ GD+ + DP TPCV N++ F AFLFS+ET+TTIGYGYR Sbjct: 100 YTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRV 159 Query: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198 +T++C ++++++QS+L I+N F++G K++ +KRA+T+ FS A+I MRDGKLC Sbjct: 160 ITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLC 219 Query: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253 LM+R+GD R +H+VE ++RA+L++ + SEG + + D+ + +D++ LV+P+ I Sbjct: 220 LMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLII 279 Query: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313 HEI+ +SP + + + + K+ EI+V ++TG + Q+RSSY+ EILWG+RF V Sbjct: 280 SHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPV 339 Query: 314 LEVKRKYYKVNCLQFEGSVEVYAPFCSAKQL 344 L ++ +Y+V+ F + E P SAK+L Sbjct: 340 LTLEDGFYEVDYNSFHETYETSTPSLSAKEL 370 >gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] Length = 419 Score = 278 bits (712), Expect = 5e-75 Identities = 136/349 (38%), Positives = 228/349 (65%), Gaps = 11/349 (3%) Query: 25 IIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILS 84 ++AE ++ R+R + K G CNV+ ++ E Y+ D+FTTLVD KWR ++F++ Y ++ Sbjct: 42 LLAEGKKPRQRYMEKSGKCNVHHGNV-QETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVT 100 Query: 85 WLIFGSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEE 142 WL FG ++WLIA+ GDL + D + PCV+N+ F AFLFS+ET+TTIGYG+R +TE+ Sbjct: 101 WLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEK 160 Query: 143 CSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWR 202 C ++++++Q+IL I+N F++G K++ +KRA+T+ FS A+I MRD KLCLM+R Sbjct: 161 CPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFR 220 Query: 203 IGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEI 257 +GD R +H+VE ++RA+L++ + EG + + D+ + +D++ LV+P+ I HEI Sbjct: 221 VGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEI 280 Query: 258 DHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVK 317 + +SP + + + + ++ FE++V ++TG + Q+RSSY+ E+LWGHRF VL ++ Sbjct: 281 NQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLE 340 Query: 318 RKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQ---LHIEKAPPVRESC 363 + +Y+V+ F + E P C AK+L ++ L +PP+ C Sbjct: 341 KGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGC 389 >gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] Length = 501 Score = 268 bits (686), Expect = 5e-72 Identities = 144/385 (37%), Positives = 230/385 (59%), Gaps = 22/385 (5%) Query: 4 YGSSYHIINADA-------KYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGS 56 +G Y ++ + + PG P+ + K++ R+R + K+G CNV ++ E Sbjct: 8 FGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSR 66 Query: 57 YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDN 114 Y+ D+FTTLVD KWR IF L+Y ++WL S++W+IA+ GDL + + TPCV N Sbjct: 67 YLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVAN 126 Query: 115 VHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMAT 174 V++F AFLF +ET+ TIGYGYR +T++C +++ + QSIL I++ F+IG KM+ Sbjct: 127 VYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQ 186 Query: 175 ARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMA 234 +KRA+T+ FS A+I MRDGKL LM+R+G+ R +H+V +R +LL+ + EG + Sbjct: 187 PKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEF-LP 245 Query: 235 FKDLKL------VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDS 288 L+L DQ+ LV+P+TI H ID +SP Y L ++++ + FEI+V ++ Sbjct: 246 LDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVET 305 Query: 289 TGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKD 348 TG + Q+R+SY E+LWGHRF V+ ++ ++KV+ QF + EV P S K+ Sbjct: 306 TGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSV-----KE 360 Query: 349 QQLHIEKAPPVRESCTSDTKARRRS 373 Q+ + + P+ +++K R S Sbjct: 361 QEEMLLMSSPLIAPAITNSKERHNS 385 >gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] Length = 424 Score = 266 bits (681), Expect = 2e-71 Identities = 138/333 (41%), Positives = 208/333 (62%), Gaps = 16/333 (4%) Query: 30 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89 R + R + K G+CN+ K+I E G ++ DIFTTLVD KWRH VIF++S++ SWL+F Sbjct: 30 RLPKARFIAKSGACNLAHKNI-REQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFA 88 Query: 90 SVFWLIAFHHGDLL----------NDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCV 139 ++WL+AF HGD+ + + T CV NV SFT AFLFS+E Q TIG+G R + Sbjct: 89 IMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMM 148 Query: 140 TEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCL 199 TEEC +A+ ++ILQ+I+ IIN ++G K A A +RA+T+ FS A+I +R+GKLC Sbjct: 149 TEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCF 208 Query: 200 MWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFK-----DLKLVNDQIILVTPVTIV 254 M+R+GD R + ++ +VR Q+++ T EG + + D + ++ I LV P+ I Sbjct: 209 MFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIIC 268 Query: 255 HEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL 314 H ID SPLY + +A + E++V ++TG + Q+R+SY+ EI WGHRF ++ Sbjct: 269 HVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIV 328 Query: 315 EVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWK 347 + Y V+ +F +V+V AP CSA++LD K Sbjct: 329 TEEEGVYSVDYSKFGNTVKVAAPRCSARELDEK 361 >gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapiens] Length = 390 Score = 257 bits (657), Expect = 1e-68 Identities = 136/323 (42%), Positives = 204/323 (63%), Gaps = 8/323 (2%) Query: 30 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89 R+ R R + K G+CNV K+I E G ++ D+FTTLVD KW H +IF++S++ SWL+F Sbjct: 29 RQRRARFVSKKGNCNVAHKNI-REQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87 Query: 90 SVFWLIAFHHGDLL-NDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVL 148 +WLIAF HGDL ++ PCV ++HSF+ AFLFS+E Q TIG+G R VTEEC +A+L Sbjct: 88 MAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAIL 147 Query: 149 MVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRP 208 ++I+Q+I+ +IN ++G K A A +RA+T+ FS A+I +R G+LC M R+GD R Sbjct: 148 ILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRK 207 Query: 209 NHVVEGTVRAQLLRYTEDSEGRMTMAFK-DLKLVN----DQIILVTPVTIVHEIDHESPL 263 + ++ T+ Q++R T EG + + D+ + N + I LV P+ I H ID SPL Sbjct: 208 SMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPL 267 Query: 264 YALDRKAV-AKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYK 322 Y L + + EI+V ++TG + Q+R+SY+ EILWG RF ++ + Y Sbjct: 268 YDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYS 327 Query: 323 VNCLQFEGSVEVYAPFCSAKQLD 345 V+ +F +V+V P C+A+QLD Sbjct: 328 VDYSKFGNTVKVPTPLCTARQLD 350 >gi|24497471 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 250 bits (638), Expect = 2e-66 Identities = 132/336 (39%), Positives = 209/336 (62%), Gaps = 12/336 (3%) Query: 31 RARRRLLHKDGSCNVYFKHIFGEWGS-YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89 R R RL+ KDG CN+ F ++ + + VDI+TT++D KWR+ IF +++ SW FG Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77 Query: 90 SVFWLIAFHHGDLLN---DPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 +++ +A+ H DL + TPCV+N++ T AFLFSLETQ TIGYG+RCVTE+C+ A Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 + ++I QSIL IIN+F+ GA LAK++ +KRA+TI FS A+I R GKLCL+ R+ + Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197 Query: 207 RPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL------VNDQIILVTPVTIVHEIDHE 260 R + ++ + +LL+ T EG T+ + + N+ + ++P+TI H IDH Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGE-TIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256 Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL-EVKRK 319 SP + + + + + +FE++V T +ST + Q R+SYVP E+LWG+RF ++ + K Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316 Query: 320 YYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEK 355 Y+V+ F +VEV P C+ + KD + +++ Sbjct: 317 KYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKR 352 >gi|24497467 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 250 bits (638), Expect = 2e-66 Identities = 132/336 (39%), Positives = 209/336 (62%), Gaps = 12/336 (3%) Query: 31 RARRRLLHKDGSCNVYFKHIFGEWGS-YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89 R R RL+ KDG CN+ F ++ + + VDI+TT++D KWR+ IF +++ SW FG Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77 Query: 90 SVFWLIAFHHGDLLN---DPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 +++ +A+ H DL + TPCV+N++ T AFLFSLETQ TIGYG+RCVTE+C+ A Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 + ++I QSIL IIN+F+ GA LAK++ +KRA+TI FS A+I R GKLCL+ R+ + Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197 Query: 207 RPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL------VNDQIILVTPVTIVHEIDHE 260 R + ++ + +LL+ T EG T+ + + N+ + ++P+TI H IDH Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGE-TIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256 Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL-EVKRK 319 SP + + + + + +FE++V T +ST + Q R+SYVP E+LWG+RF ++ + K Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316 Query: 320 YYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEK 355 Y+V+ F +VEV P C+ + KD + +++ Sbjct: 317 KYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKR 352 >gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo sapiens] Length = 391 Score = 250 bits (638), Expect = 2e-66 Identities = 132/336 (39%), Positives = 209/336 (62%), Gaps = 12/336 (3%) Query: 31 RARRRLLHKDGSCNVYFKHIFGEWGS-YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89 R R RL+ KDG CN+ F ++ + + VDI+TT++D KWR+ IF +++ SW FG Sbjct: 37 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 96 Query: 90 SVFWLIAFHHGDLLN---DPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 +++ +A+ H DL + TPCV+N++ T AFLFSLETQ TIGYG+RCVTE+C+ A Sbjct: 97 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 156 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 + ++I QSIL IIN+F+ GA LAK++ +KRA+TI FS A+I R GKLCL+ R+ + Sbjct: 157 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 216 Query: 207 RPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL------VNDQIILVTPVTIVHEIDHE 260 R + ++ + +LL+ T EG T+ + + N+ + ++P+TI H IDH Sbjct: 217 RKSLLIGSHIYGKLLKTTVTPEGE-TIILDQININFVVDAGNENLFFISPLTIYHVIDHN 275 Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL-EVKRK 319 SP + + + + + +FE++V T +ST + Q R+SYVP E+LWG+RF ++ + K Sbjct: 276 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 335 Query: 320 YYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEK 355 Y+V+ F +VEV P C+ + KD + +++ Sbjct: 336 KYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKR 371 >gi|148539892 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 250 bits (638), Expect = 2e-66 Identities = 132/336 (39%), Positives = 209/336 (62%), Gaps = 12/336 (3%) Query: 31 RARRRLLHKDGSCNVYFKHIFGEWGS-YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89 R R RL+ KDG CN+ F ++ + + VDI+TT++D KWR+ IF +++ SW FG Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77 Query: 90 SVFWLIAFHHGDLLN---DPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 +++ +A+ H DL + TPCV+N++ T AFLFSLETQ TIGYG+RCVTE+C+ A Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 + ++I QSIL IIN+F+ GA LAK++ +KRA+TI FS A+I R GKLCL+ R+ + Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197 Query: 207 RPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL------VNDQIILVTPVTIVHEIDHE 260 R + ++ + +LL+ T EG T+ + + N+ + ++P+TI H IDH Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGE-TIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256 Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL-EVKRK 319 SP + + + + + +FE++V T +ST + Q R+SYVP E+LWG+RF ++ + K Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316 Query: 320 YYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEK 355 Y+V+ F +VEV P C+ + KD + +++ Sbjct: 317 KYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKR 352 >gi|24497473 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 250 bits (638), Expect = 2e-66 Identities = 132/336 (39%), Positives = 209/336 (62%), Gaps = 12/336 (3%) Query: 31 RARRRLLHKDGSCNVYFKHIFGEWGS-YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89 R R RL+ KDG CN+ F ++ + + VDI+TT++D KWR+ IF +++ SW FG Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77 Query: 90 SVFWLIAFHHGDLLN---DPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146 +++ +A+ H DL + TPCV+N++ T AFLFSLETQ TIGYG+RCVTE+C+ A Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137 Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206 + ++I QSIL IIN+F+ GA LAK++ +KRA+TI FS A+I R GKLCL+ R+ + Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197 Query: 207 RPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL------VNDQIILVTPVTIVHEIDHE 260 R + ++ + +LL+ T EG T+ + + N+ + ++P+TI H IDH Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGE-TIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256 Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL-EVKRK 319 SP + + + + + +FE++V T +ST + Q R+SYVP E+LWG+RF ++ + K Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316 Query: 320 YYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEK 355 Y+V+ F +VEV P C+ + KD + +++ Sbjct: 317 KYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKR 352 >gi|25121966 potassium inwardly-rectifying channel, subfamily J, member 10 [Homo sapiens] Length = 379 Score = 226 bits (576), Expect = 3e-59 Identities = 124/315 (39%), Positives = 196/315 (62%), Gaps = 12/315 (3%) Query: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92 RRR+L KDG NV +HI + Y+ D++TT +D +WR+ ++FS ++ +W +FG V+ Sbjct: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86 Query: 93 WLIAFHHGDLLN-DPDI--TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149 +L+A HGDLL DP TPCV VH+ TGAFLFSLE+QTTIGYG+R ++EEC +A+++ Sbjct: 87 YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146 Query: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209 +I Q +L+ I+ FI G LAK+A +KRA+TIRFS A++ +GK CLM R+ + R + Sbjct: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206 Query: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263 ++ V +LL+ + EG ++ + F+ + +D L+ P+T H +D SPL Sbjct: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQ-VDTASDSPFLILPLTFYHVVDETSPL 265 Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRK-YYK 322 L ++ + +FE+++ T +ST + Q R+SY+P EILWG+ F + + Y Sbjct: 266 KDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYI 324 Query: 323 VNCLQFEGSVEVYAP 337 + F+ V+V +P Sbjct: 325 ADFSLFDQVVKVASP 339 >gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapiens] Length = 375 Score = 216 bits (551), Expect = 2e-56 Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%) Query: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92 R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++ Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 Query: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149 + IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ + Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 Query: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209 ++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R + Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 Query: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263 +++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264 Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322 L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y Sbjct: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324 Query: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351 + QFE + +P C+ D + QQL Sbjct: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351 >gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapiens] Length = 375 Score = 216 bits (551), Expect = 2e-56 Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%) Query: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92 R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++ Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 Query: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149 + IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ + Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 Query: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209 ++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R + Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 Query: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263 +++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264 Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322 L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y Sbjct: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324 Query: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351 + QFE + +P C+ D + QQL Sbjct: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351 >gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapiens] Length = 375 Score = 216 bits (551), Expect = 2e-56 Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%) Query: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92 R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++ Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 Query: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149 + IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ + Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 Query: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209 ++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R + Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 Query: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263 +++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264 Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322 L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y Sbjct: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324 Query: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351 + QFE + +P C+ D + QQL Sbjct: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351 >gi|156119627 potassium inwardly-rectifying channel J13 [Homo sapiens] Length = 360 Score = 156 bits (395), Expect = 3e-38 Identities = 105/331 (31%), Positives = 175/331 (52%), Gaps = 16/331 (4%) Query: 34 RRLLHKDGSCNVYFKHIFGEWG-SYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92 RR++ KDG + + G +Y+ D + L+D +WR M ++FS S+++ WL+F ++ Sbjct: 18 RRMVTKDGHSTLQMDG--AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLW 75 Query: 93 WLIAFHHGDLLNDPDITP-----CVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAV 147 +++A +GDL D D P CV + SFT AF FSLETQ TIGYG + +C A+ Sbjct: 76 YVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135 Query: 148 LMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFR 207 ++ +Q +L ++ FI GA +AK+A + RA +IRF+ A++ DGK L++++ + R Sbjct: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195 Query: 208 PNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHESPL 263 P+ + +VR + Y E G++ D L ++ + P+T H I SPL Sbjct: 196 PSPLT--SVRVSAVLYQERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSPL 253 Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRK-YYK 322 L + +FE++V + TG Q R+SY+P EI+ H F +L K Y+ Sbjct: 254 ATL-LQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEYQ 312 Query: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQLHI 353 + F+ +V + +K + D +HI Sbjct: 313 IKMENFDKTVPEFPTPLVSKSPNRTDLDIHI 343 >gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 precursor [Homo sapiens] Length = 490 Score = 29.3 bits (64), Expect = 6.9 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 8/78 (10%) Query: 19 GYPPEHIIAEKRRARRRLLH--KDGSCNVYFKH--IFGEWGSYVVDIFTTLVDTKWRHMF 74 GYP HI+ E+ R + ++H G N K + G+ G + T +D ++ Sbjct: 416 GYPRSHILTEEERQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQ-NTHAID---KYSR 471 Query: 75 VIFSLSYILSWLIFGSVF 92 +IF SYI LI+ SVF Sbjct: 472 LIFPASYIFFNLIYWSVF 489 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.137 0.421 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,312,926 Number of Sequences: 37866 Number of extensions: 621366 Number of successful extensions: 1822 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 1724 Number of HSP's gapped (non-prelim): 35 length of query: 418 length of database: 18,247,518 effective HSP length: 105 effective length of query: 313 effective length of database: 14,271,588 effective search space: 4467007044 effective search space used: 4467007044 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.