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Search of human proteins with 25777628
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
(418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 853 0.0
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 853 0.0
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 853 0.0
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 322 5e-88
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 322 5e-88
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 321 9e-88
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 315 6e-86
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 312 3e-85
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 304 1e-82
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 304 1e-82
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 303 1e-82
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 303 1e-82
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 303 1e-82
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 286 2e-77
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 284 1e-76
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 278 5e-75
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 268 5e-72
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 266 2e-71
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 257 1e-68
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 250 2e-66
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 250 2e-66
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 250 2e-66
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 250 2e-66
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 250 2e-66
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 226 3e-59
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 216 2e-56
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 216 2e-56
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 216 2e-56
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 156 3e-38
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec... 29 6.9
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 853 bits (2204), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60
MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD
Sbjct: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60
Query: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120
IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG
Sbjct: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120
Query: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180
AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ
Sbjct: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180
Query: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240
TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL
Sbjct: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240
Query: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300
VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV
Sbjct: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300
Query: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360
PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR
Sbjct: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360
Query: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418
ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM
Sbjct: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 853 bits (2204), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60
MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD
Sbjct: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60
Query: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120
IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG
Sbjct: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120
Query: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180
AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ
Sbjct: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180
Query: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240
TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL
Sbjct: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240
Query: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300
VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV
Sbjct: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300
Query: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360
PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR
Sbjct: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360
Query: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418
ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM
Sbjct: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 853 bits (2204), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60
MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD
Sbjct: 1 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD 60
Query: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120
IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG
Sbjct: 61 IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG 120
Query: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180
AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ
Sbjct: 121 AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ 180
Query: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240
TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL
Sbjct: 181 TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL 240
Query: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300
VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV
Sbjct: 241 VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV 300
Query: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360
PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR
Sbjct: 301 PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR 360
Query: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418
ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM
Sbjct: 361 ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM 418
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 322 bits (824), Expect = 5e-88
Identities = 162/354 (45%), Positives = 239/354 (67%), Gaps = 26/354 (7%)
Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
+R+ R R + K+G CNVYF ++ + Y+ DIFTT VDT+WR+M +IFS ++++SWL F
Sbjct: 14 RRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFF 73
Query: 89 GSVFWLIAFHHGDLLNDPDIT------------------PCVDNVHSFTGAFLFSLETQT 130
G +FW IAF HGDL P + PC+ +V+ F GAFLFS+ETQT
Sbjct: 74 GLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQT 133
Query: 131 TIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALI 190
TIGYG+RCVTEEC +AV+ V++QSI+ C+I++F+IG +AKMA +KRAQT+ FS+ A+I
Sbjct: 134 TIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVI 193
Query: 191 GMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLK----LVNDQI 245
+RDGKLCLMWR+G+ R +H+VE VRAQL++ EG + + +DL + D+I
Sbjct: 194 SVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRI 253
Query: 246 ILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREIL 305
LV+P+ IVHEID +SPLY + ++ + ++FEI+V ++T + Q+RSSY+ EIL
Sbjct: 254 FLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
Query: 306 WGHRFNDVLEVKRKYYKVNCLQFEGSVEVY-APFCSAKQLDWKDQQLHIEKAPP 358
WGHRF V+ ++ +YKV+ +F + EV P CSA++L ++ ++ + APP
Sbjct: 314 WGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSAREL--QESKITVLPAPP 365
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 322 bits (824), Expect = 5e-88
Identities = 162/354 (45%), Positives = 239/354 (67%), Gaps = 26/354 (7%)
Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
+R+ R R + K+G CNVYF ++ + Y+ DIFTT VDT+WR+M +IFS ++++SWL F
Sbjct: 14 RRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFF 73
Query: 89 GSVFWLIAFHHGDLLNDPDIT------------------PCVDNVHSFTGAFLFSLETQT 130
G +FW IAF HGDL P + PC+ +V+ F GAFLFS+ETQT
Sbjct: 74 GLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQT 133
Query: 131 TIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALI 190
TIGYG+RCVTEEC +AV+ V++QSI+ C+I++F+IG +AKMA +KRAQT+ FS+ A+I
Sbjct: 134 TIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVI 193
Query: 191 GMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLK----LVNDQI 245
+RDGKLCLMWR+G+ R +H+VE VRAQL++ EG + + +DL + D+I
Sbjct: 194 SVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRI 253
Query: 246 ILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREIL 305
LV+P+ IVHEID +SPLY + ++ + ++FEI+V ++T + Q+RSSY+ EIL
Sbjct: 254 FLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
Query: 306 WGHRFNDVLEVKRKYYKVNCLQFEGSVEVY-APFCSAKQLDWKDQQLHIEKAPP 358
WGHRF V+ ++ +YKV+ +F + EV P CSA++L ++ ++ + APP
Sbjct: 314 WGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSAREL--QESKITVLPAPP 365
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 321 bits (822), Expect = 9e-88
Identities = 166/322 (51%), Positives = 222/322 (68%), Gaps = 6/322 (1%)
Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
+++ R R + KDG CNV F ++ + Y+ DIFTT VD +WR M VIF L+++LSWL F
Sbjct: 40 RQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFF 99
Query: 89 GSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVL 148
G VFWLIA HGDL + CV V+SFT AFLFS+ETQTTIGYG+RCVT+EC +AV
Sbjct: 100 GCVFWLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVF 159
Query: 149 MVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRP 208
MV+ QSI+ CII+ FIIGA +AKMA +KR +T+ FS+ A+I MRDGKLCLMWR+G+ R
Sbjct: 160 MVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRK 219
Query: 209 NHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEIDHESPL 263
+H+VE VRAQLL+ SEG + + D+ + D+I LV+P+TIVHEID +SPL
Sbjct: 220 SHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPL 279
Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKV 323
Y L ++ + +FEI+V ++T + Q RSSY+ EILWGHR+ VL ++ YYKV
Sbjct: 280 YDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKV 339
Query: 324 NCLQFEGSVEV-YAPFCSAKQL 344
+ +F + EV P CSA+ L
Sbjct: 340 DYSRFHKTYEVPNTPLCSARDL 361
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 315 bits (806), Expect = 6e-86
Identities = 163/325 (50%), Positives = 224/325 (68%), Gaps = 10/325 (3%)
Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
+RR R R + K+G CN+ F ++ + Y+ D+FTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 39 RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
G +FW+IA HGDL TPCV VH F AFLFS+ETQTTIGYG RCVTEEC VA
Sbjct: 99 GIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVA 158
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
V MV+ QSI+ CII++F+IGA +AKMA +KRAQT+ FS+ A++ +RDGKLCLMWR+G+
Sbjct: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNL 218
Query: 207 RPNHVVEGTVRAQLL--RYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHE 260
R +H+VE VRAQL+ R TE+ E + + D+ + D+I LV+P+TI+HEID
Sbjct: 219 RKSHIVEAHVRAQLIKPRVTEEGE-YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY 320
SPL+ + R+ + D+FEI+V ++T + Q+RSSY+ EILWGHRF VL ++
Sbjct: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
Query: 321 YKVNCLQFEGSVEV-YAPFCSAKQL 344
YK++ F + EV P CSAK L
Sbjct: 338 YKIDYSHFHKTYEVPSTPRCSAKDL 362
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 312 bits (800), Expect = 3e-85
Identities = 162/325 (49%), Positives = 223/325 (68%), Gaps = 10/325 (3%)
Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
+RR R R + K+G CN+ F ++ + Y+ D+FTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 39 RRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLF 98
Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
G +FW+IA HGDL TPCV VH F AFLFS+ETQTTIGYG RCVTEEC VA
Sbjct: 99 GVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVA 158
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
V MV+ QSI+ CII++F+IGA +AKMA +KRA T+ FS+ A++ +RDGKLCLMWR+G+
Sbjct: 159 VFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNL 218
Query: 207 RPNHVVEGTVRAQLL--RYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHE 260
R +H+VE VRAQL+ R TE+ E + + D+ + D+I LV+P+TI+HEID
Sbjct: 219 RKSHIVEAHVRAQLIKPRVTEEGE-YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY 320
SPL+ + R+ + D+FEI+V ++T + Q+RSSY+ EILWGHRF VL ++
Sbjct: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
Query: 321 YKVNCLQFEGSVEV-YAPFCSAKQL 344
YK++ F + EV P CSAK L
Sbjct: 338 YKIDYSHFHKTYEVPSTPRCSAKDL 362
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 304 bits (778), Expect = 1e-82
Identities = 158/338 (46%), Positives = 220/338 (65%), Gaps = 6/338 (1%)
Query: 19 GYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFS 78
G+ P + + R R R + KDG CNV F ++ G+ Y+ D+FTT VD +WR M ++FS
Sbjct: 35 GWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFS 94
Query: 79 LSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138
S++ SWL+FG FWLIA HGDL P PC +V SF AFLF+LETQT+IGYG R
Sbjct: 95 CSFLASWLLFGLAFWLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRS 154
Query: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198
VTEEC AV V+LQ I C+++ F++GA +AKMA +KR +T+ FS A++ +RD +LC
Sbjct: 155 VTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLC 214
Query: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253
LMWR+G+ R +H+VE VRAQLL+ EG + + +D+ + D+I LV+P+TI
Sbjct: 215 LMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITI 274
Query: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313
VHEID SPLY L R +A+ +FE++V ++T + Q RSSY+P E+LWGHRF V
Sbjct: 275 VHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPV 334
Query: 314 LEVKRKYYKVNCLQFEGSVEV-YAPFCSAKQLDWKDQQ 350
L + Y+V+ F + EV P CSAK+LD + +Q
Sbjct: 335 LFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQ 372
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 304 bits (778), Expect = 1e-82
Identities = 158/338 (46%), Positives = 220/338 (65%), Gaps = 6/338 (1%)
Query: 19 GYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFS 78
G+ P + + R R R + KDG CNV F ++ G+ Y+ D+FTT VD +WR M ++FS
Sbjct: 35 GWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFS 94
Query: 79 LSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138
S++ SWL+FG FWLIA HGDL P PC +V SF AFLF+LETQT+IGYG R
Sbjct: 95 CSFLASWLLFGLAFWLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRS 154
Query: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198
VTEEC AV V+LQ I C+++ F++GA +AKMA +KR +T+ FS A++ +RD +LC
Sbjct: 155 VTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLC 214
Query: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253
LMWR+G+ R +H+VE VRAQLL+ EG + + +D+ + D+I LV+P+TI
Sbjct: 215 LMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITI 274
Query: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313
VHEID SPLY L R +A+ +FE++V ++T + Q RSSY+P E+LWGHRF V
Sbjct: 275 VHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPV 334
Query: 314 LEVKRKYYKVNCLQFEGSVEV-YAPFCSAKQLDWKDQQ 350
L + Y+V+ F + EV P CSAK+LD + +Q
Sbjct: 335 LFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQ 372
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 303 bits (777), Expect = 1e-82
Identities = 156/324 (48%), Positives = 217/324 (66%), Gaps = 9/324 (2%)
Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
+RR R + K+G CN+ F ++ + Y+ DIFTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 39 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 98
Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
G +FW+IA HGDL TPCV VH F AFLFS++TQ TI YG RCVTEEC VA
Sbjct: 99 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 158
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
V MV+ QSI+ CIIN+F+IGA +AKM +KRAQT+ FS+ A++ +RDGKLC MWR+G+
Sbjct: 159 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 218
Query: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKLVNDQ----IILVTPVTIVHEIDHES 261
R +H+VE VRAQL++ EG + + D+ + D+ LV+P+TI+HEID S
Sbjct: 219 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 278
Query: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321
PL+ + R+ + D+FEI++ ++T + Q+RSSY+ EILWGHRF VL ++ Y
Sbjct: 279 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 337
Query: 322 KVNCLQFEGSVEV-YAPFCSAKQL 344
K++ L F + EV P CSAK L
Sbjct: 338 KIDYLHFHKTYEVPSTPRCSAKDL 361
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 303 bits (777), Expect = 1e-82
Identities = 156/324 (48%), Positives = 217/324 (66%), Gaps = 9/324 (2%)
Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
+RR R + K+G CN+ F ++ + Y+ DIFTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 141 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 200
Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
G +FW+IA HGDL TPCV VH F AFLFS++TQ TI YG RCVTEEC VA
Sbjct: 201 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 260
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
V MV+ QSI+ CIIN+F+IGA +AKM +KRAQT+ FS+ A++ +RDGKLC MWR+G+
Sbjct: 261 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 320
Query: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKLVNDQ----IILVTPVTIVHEIDHES 261
R +H+VE VRAQL++ EG + + D+ + D+ LV+P+TI+HEID S
Sbjct: 321 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 380
Query: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321
PL+ + R+ + D+FEI++ ++T + Q+RSSY+ EILWGHRF VL ++ Y
Sbjct: 381 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 439
Query: 322 KVNCLQFEGSVEV-YAPFCSAKQL 344
K++ L F + EV P CSAK L
Sbjct: 440 KIDYLHFHKTYEVPSTPRCSAKDL 463
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 303 bits (777), Expect = 1e-82
Identities = 156/324 (48%), Positives = 217/324 (66%), Gaps = 9/324 (2%)
Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
+RR R + K+G CN+ F ++ + Y+ DIFTT VD +WR+M +IFSL+++ SWL+F
Sbjct: 39 RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLF 98
Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
G +FW+IA HGDL TPCV VH F AFLFS++TQ TI YG RCVTEEC VA
Sbjct: 99 GVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVA 158
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
V MV+ QSI+ CIIN+F+IGA +AKM +KRAQT+ FS+ A++ +RDGKLC MWR+G+
Sbjct: 159 VFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNL 218
Query: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKLVNDQ----IILVTPVTIVHEIDHES 261
R +H+VE VRAQL++ EG + + D+ + D+ LV+P+TI+HEID S
Sbjct: 219 RKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEAS 278
Query: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321
PL+ + R+ + D+FEI++ ++T + Q+RSSY+ EILWGHRF VL ++ Y
Sbjct: 279 PLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQY 337
Query: 322 KVNCLQFEGSVEV-YAPFCSAKQL 344
K++ L F + EV P CSAK L
Sbjct: 338 KIDYLHFHKTYEVPSTPRCSAKDL 361
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 286 bits (733), Expect = 2e-77
Identities = 141/323 (43%), Positives = 219/323 (67%), Gaps = 8/323 (2%)
Query: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
+RR R+R + KDG CNV ++ E Y+ D+FTTLVD +WR + F L+Y L+WL F
Sbjct: 17 RRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
Query: 89 GSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
G+++WLIA+ GDL L D TPCV+N++ F AFLFS+ET+TTIGYG+R +T++C
Sbjct: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
+++++LQ+IL ++N F++G K++ KRA T+ FS A++ +RDG+LCLM+R+GD
Sbjct: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
Query: 207 RPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEIDHES 261
R +H+VE ++RA+L+R + EG + + DL + +D++ LV+P+ I HEID S
Sbjct: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
Query: 262 PLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYY 321
P + R+A+ +D+FEI+V ++TG + Q+RSSY+ E+LWGHRF VL ++ +Y
Sbjct: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
Query: 322 KVNCLQFEGSVEVYAPFCSAKQL 344
+V+ F + EV P CSA++L
Sbjct: 316 EVDYASFHETFEVPTPSCSAREL 338
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 284 bits (726), Expect = 1e-76
Identities = 140/331 (42%), Positives = 221/331 (66%), Gaps = 9/331 (2%)
Query: 22 PEHIIAEK-RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLS 80
P HI ++ +R +R + KDG CNV+ ++ E Y+ DIFTTLVD KWR +IF +
Sbjct: 41 PRHISRDRTKRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMV 99
Query: 81 YILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138
Y ++WL FG ++WLIA+ GD+ + DP TPCV N++ F AFLFS+ET+TTIGYGYR
Sbjct: 100 YTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRV 159
Query: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198
+T++C ++++++QS+L I+N F++G K++ +KRA+T+ FS A+I MRDGKLC
Sbjct: 160 ITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLC 219
Query: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253
LM+R+GD R +H+VE ++RA+L++ + SEG + + D+ + +D++ LV+P+ I
Sbjct: 220 LMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLII 279
Query: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313
HEI+ +SP + + + + K+ EI+V ++TG + Q+RSSY+ EILWG+RF V
Sbjct: 280 SHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPV 339
Query: 314 LEVKRKYYKVNCLQFEGSVEVYAPFCSAKQL 344
L ++ +Y+V+ F + E P SAK+L
Sbjct: 340 LTLEDGFYEVDYNSFHETYETSTPSLSAKEL 370
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 278 bits (712), Expect = 5e-75
Identities = 136/349 (38%), Positives = 228/349 (65%), Gaps = 11/349 (3%)
Query: 25 IIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILS 84
++AE ++ R+R + K G CNV+ ++ E Y+ D+FTTLVD KWR ++F++ Y ++
Sbjct: 42 LLAEGKKPRQRYMEKSGKCNVHHGNV-QETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVT 100
Query: 85 WLIFGSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEE 142
WL FG ++WLIA+ GDL + D + PCV+N+ F AFLFS+ET+TTIGYG+R +TE+
Sbjct: 101 WLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEK 160
Query: 143 CSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWR 202
C ++++++Q+IL I+N F++G K++ +KRA+T+ FS A+I MRD KLCLM+R
Sbjct: 161 CPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFR 220
Query: 203 IGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEI 257
+GD R +H+VE ++RA+L++ + EG + + D+ + +D++ LV+P+ I HEI
Sbjct: 221 VGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEI 280
Query: 258 DHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVK 317
+ +SP + + + + ++ FE++V ++TG + Q+RSSY+ E+LWGHRF VL ++
Sbjct: 281 NQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLE 340
Query: 318 RKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQ---LHIEKAPPVRESC 363
+ +Y+V+ F + E P C AK+L ++ L +PP+ C
Sbjct: 341 KGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGC 389
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 268 bits (686), Expect = 5e-72
Identities = 144/385 (37%), Positives = 230/385 (59%), Gaps = 22/385 (5%)
Query: 4 YGSSYHIINADA-------KYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGS 56
+G Y ++ + + PG P+ + K++ R+R + K+G CNV ++ E
Sbjct: 8 FGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSR 66
Query: 57 YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDN 114
Y+ D+FTTLVD KWR IF L+Y ++WL S++W+IA+ GDL + + TPCV N
Sbjct: 67 YLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVAN 126
Query: 115 VHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMAT 174
V++F AFLF +ET+ TIGYGYR +T++C +++ + QSIL I++ F+IG KM+
Sbjct: 127 VYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQ 186
Query: 175 ARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMA 234
+KRA+T+ FS A+I MRDGKL LM+R+G+ R +H+V +R +LL+ + EG +
Sbjct: 187 PKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEF-LP 245
Query: 235 FKDLKL------VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDS 288
L+L DQ+ LV+P+TI H ID +SP Y L ++++ + FEI+V ++
Sbjct: 246 LDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVET 305
Query: 289 TGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKD 348
TG + Q+R+SY E+LWGHRF V+ ++ ++KV+ QF + EV P S K+
Sbjct: 306 TGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSV-----KE 360
Query: 349 QQLHIEKAPPVRESCTSDTKARRRS 373
Q+ + + P+ +++K R S
Sbjct: 361 QEEMLLMSSPLIAPAITNSKERHNS 385
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 266 bits (681), Expect = 2e-71
Identities = 138/333 (41%), Positives = 208/333 (62%), Gaps = 16/333 (4%)
Query: 30 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
R + R + K G+CN+ K+I E G ++ DIFTTLVD KWRH VIF++S++ SWL+F
Sbjct: 30 RLPKARFIAKSGACNLAHKNI-REQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFA 88
Query: 90 SVFWLIAFHHGDLL----------NDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCV 139
++WL+AF HGD+ + + T CV NV SFT AFLFS+E Q TIG+G R +
Sbjct: 89 IMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMM 148
Query: 140 TEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCL 199
TEEC +A+ ++ILQ+I+ IIN ++G K A A +RA+T+ FS A+I +R+GKLC
Sbjct: 149 TEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCF 208
Query: 200 MWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFK-----DLKLVNDQIILVTPVTIV 254
M+R+GD R + ++ +VR Q+++ T EG + + D + ++ I LV P+ I
Sbjct: 209 MFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIIC 268
Query: 255 HEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL 314
H ID SPLY + +A + E++V ++TG + Q+R+SY+ EI WGHRF ++
Sbjct: 269 HVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIV 328
Query: 315 EVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWK 347
+ Y V+ +F +V+V AP CSA++LD K
Sbjct: 329 TEEEGVYSVDYSKFGNTVKVAAPRCSARELDEK 361
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 257 bits (657), Expect = 1e-68
Identities = 136/323 (42%), Positives = 204/323 (63%), Gaps = 8/323 (2%)
Query: 30 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
R+ R R + K G+CNV K+I E G ++ D+FTTLVD KW H +IF++S++ SWL+F
Sbjct: 29 RQRRARFVSKKGNCNVAHKNI-REQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87
Query: 90 SVFWLIAFHHGDLL-NDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVL 148
+WLIAF HGDL ++ PCV ++HSF+ AFLFS+E Q TIG+G R VTEEC +A+L
Sbjct: 88 MAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAIL 147
Query: 149 MVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRP 208
++I+Q+I+ +IN ++G K A A +RA+T+ FS A+I +R G+LC M R+GD R
Sbjct: 148 ILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRK 207
Query: 209 NHVVEGTVRAQLLRYTEDSEGRMTMAFK-DLKLVN----DQIILVTPVTIVHEIDHESPL 263
+ ++ T+ Q++R T EG + + D+ + N + I LV P+ I H ID SPL
Sbjct: 208 SMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPL 267
Query: 264 YALDRKAV-AKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYK 322
Y L + + EI+V ++TG + Q+R+SY+ EILWG RF ++ + Y
Sbjct: 268 YDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYS 327
Query: 323 VNCLQFEGSVEVYAPFCSAKQLD 345
V+ +F +V+V P C+A+QLD
Sbjct: 328 VDYSKFGNTVKVPTPLCTARQLD 350
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 250 bits (638), Expect = 2e-66
Identities = 132/336 (39%), Positives = 209/336 (62%), Gaps = 12/336 (3%)
Query: 31 RARRRLLHKDGSCNVYFKHIFGEWGS-YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
R R RL+ KDG CN+ F ++ + + VDI+TT++D KWR+ IF +++ SW FG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 90 SVFWLIAFHHGDLLN---DPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
+++ +A+ H DL + TPCV+N++ T AFLFSLETQ TIGYG+RCVTE+C+ A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
+ ++I QSIL IIN+F+ GA LAK++ +KRA+TI FS A+I R GKLCL+ R+ +
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 207 RPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL------VNDQIILVTPVTIVHEIDHE 260
R + ++ + +LL+ T EG T+ + + N+ + ++P+TI H IDH
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGE-TIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256
Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL-EVKRK 319
SP + + + + + +FE++V T +ST + Q R+SYVP E+LWG+RF ++ + K
Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316
Query: 320 YYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEK 355
Y+V+ F +VEV P C+ + KD + +++
Sbjct: 317 KYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKR 352
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 250 bits (638), Expect = 2e-66
Identities = 132/336 (39%), Positives = 209/336 (62%), Gaps = 12/336 (3%)
Query: 31 RARRRLLHKDGSCNVYFKHIFGEWGS-YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
R R RL+ KDG CN+ F ++ + + VDI+TT++D KWR+ IF +++ SW FG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 90 SVFWLIAFHHGDLLN---DPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
+++ +A+ H DL + TPCV+N++ T AFLFSLETQ TIGYG+RCVTE+C+ A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
+ ++I QSIL IIN+F+ GA LAK++ +KRA+TI FS A+I R GKLCL+ R+ +
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 207 RPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL------VNDQIILVTPVTIVHEIDHE 260
R + ++ + +LL+ T EG T+ + + N+ + ++P+TI H IDH
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGE-TIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256
Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL-EVKRK 319
SP + + + + + +FE++V T +ST + Q R+SYVP E+LWG+RF ++ + K
Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316
Query: 320 YYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEK 355
Y+V+ F +VEV P C+ + KD + +++
Sbjct: 317 KYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKR 352
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 250 bits (638), Expect = 2e-66
Identities = 132/336 (39%), Positives = 209/336 (62%), Gaps = 12/336 (3%)
Query: 31 RARRRLLHKDGSCNVYFKHIFGEWGS-YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
R R RL+ KDG CN+ F ++ + + VDI+TT++D KWR+ IF +++ SW FG
Sbjct: 37 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 96
Query: 90 SVFWLIAFHHGDLLN---DPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
+++ +A+ H DL + TPCV+N++ T AFLFSLETQ TIGYG+RCVTE+C+ A
Sbjct: 97 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 156
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
+ ++I QSIL IIN+F+ GA LAK++ +KRA+TI FS A+I R GKLCL+ R+ +
Sbjct: 157 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 216
Query: 207 RPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL------VNDQIILVTPVTIVHEIDHE 260
R + ++ + +LL+ T EG T+ + + N+ + ++P+TI H IDH
Sbjct: 217 RKSLLIGSHIYGKLLKTTVTPEGE-TIILDQININFVVDAGNENLFFISPLTIYHVIDHN 275
Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL-EVKRK 319
SP + + + + + +FE++V T +ST + Q R+SYVP E+LWG+RF ++ + K
Sbjct: 276 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 335
Query: 320 YYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEK 355
Y+V+ F +VEV P C+ + KD + +++
Sbjct: 336 KYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKR 371
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 250 bits (638), Expect = 2e-66
Identities = 132/336 (39%), Positives = 209/336 (62%), Gaps = 12/336 (3%)
Query: 31 RARRRLLHKDGSCNVYFKHIFGEWGS-YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
R R RL+ KDG CN+ F ++ + + VDI+TT++D KWR+ IF +++ SW FG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 90 SVFWLIAFHHGDLLN---DPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
+++ +A+ H DL + TPCV+N++ T AFLFSLETQ TIGYG+RCVTE+C+ A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
+ ++I QSIL IIN+F+ GA LAK++ +KRA+TI FS A+I R GKLCL+ R+ +
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 207 RPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL------VNDQIILVTPVTIVHEIDHE 260
R + ++ + +LL+ T EG T+ + + N+ + ++P+TI H IDH
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGE-TIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256
Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL-EVKRK 319
SP + + + + + +FE++V T +ST + Q R+SYVP E+LWG+RF ++ + K
Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316
Query: 320 YYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEK 355
Y+V+ F +VEV P C+ + KD + +++
Sbjct: 317 KYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKR 352
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 250 bits (638), Expect = 2e-66
Identities = 132/336 (39%), Positives = 209/336 (62%), Gaps = 12/336 (3%)
Query: 31 RARRRLLHKDGSCNVYFKHIFGEWGS-YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
R R RL+ KDG CN+ F ++ + + VDI+TT++D KWR+ IF +++ SW FG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 90 SVFWLIAFHHGDLLN---DPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVA 146
+++ +A+ H DL + TPCV+N++ T AFLFSLETQ TIGYG+RCVTE+C+ A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 147 VLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDF 206
+ ++I QSIL IIN+F+ GA LAK++ +KRA+TI FS A+I R GKLCL+ R+ +
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 207 RPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL------VNDQIILVTPVTIVHEIDHE 260
R + ++ + +LL+ T EG T+ + + N+ + ++P+TI H IDH
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGE-TIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256
Query: 261 SPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL-EVKRK 319
SP + + + + + +FE++V T +ST + Q R+SYVP E+LWG+RF ++ + K
Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316
Query: 320 YYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEK 355
Y+V+ F +VEV P C+ + KD + +++
Sbjct: 317 KYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKR 352
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 226 bits (576), Expect = 3e-59
Identities = 124/315 (39%), Positives = 196/315 (62%), Gaps = 12/315 (3%)
Query: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
RRR+L KDG NV +HI + Y+ D++TT +D +WR+ ++FS ++ +W +FG V+
Sbjct: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
Query: 93 WLIAFHHGDLLN-DPDI--TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149
+L+A HGDLL DP TPCV VH+ TGAFLFSLE+QTTIGYG+R ++EEC +A+++
Sbjct: 87 YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146
Query: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209
+I Q +L+ I+ FI G LAK+A +KRA+TIRFS A++ +GK CLM R+ + R +
Sbjct: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206
Query: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263
++ V +LL+ + EG ++ + F+ + +D L+ P+T H +D SPL
Sbjct: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQ-VDTASDSPFLILPLTFYHVVDETSPL 265
Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRK-YYK 322
L ++ + +FE+++ T +ST + Q R+SY+P EILWG+ F + + Y
Sbjct: 266 KDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYI 324
Query: 323 VNCLQFEGSVEVYAP 337
+ F+ V+V +P
Sbjct: 325 ADFSLFDQVVKVASP 339
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 216 bits (551), Expect = 2e-56
Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%)
Query: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149
+ IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ +
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209
++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R +
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263
+++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264
Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322
L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y
Sbjct: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324
Query: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351
+ QFE + +P C+ D + QQL
Sbjct: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 216 bits (551), Expect = 2e-56
Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%)
Query: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149
+ IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ +
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209
++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R +
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263
+++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264
Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322
L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y
Sbjct: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324
Query: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351
+ QFE + +P C+ D + QQL
Sbjct: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 216 bits (551), Expect = 2e-56
Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%)
Query: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149
+ IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ +
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209
++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R +
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263
+++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264
Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322
L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y
Sbjct: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324
Query: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351
+ QFE + +P C+ D + QQL
Sbjct: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 156 bits (395), Expect = 3e-38
Identities = 105/331 (31%), Positives = 175/331 (52%), Gaps = 16/331 (4%)
Query: 34 RRLLHKDGSCNVYFKHIFGEWG-SYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
RR++ KDG + + G +Y+ D + L+D +WR M ++FS S+++ WL+F ++
Sbjct: 18 RRMVTKDGHSTLQMDG--AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLW 75
Query: 93 WLIAFHHGDLLNDPDITP-----CVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAV 147
+++A +GDL D D P CV + SFT AF FSLETQ TIGYG + +C A+
Sbjct: 76 YVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135
Query: 148 LMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFR 207
++ +Q +L ++ FI GA +AK+A + RA +IRF+ A++ DGK L++++ + R
Sbjct: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195
Query: 208 PNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHESPL 263
P+ + +VR + Y E G++ D L ++ + P+T H I SPL
Sbjct: 196 PSPLT--SVRVSAVLYQERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSPL 253
Query: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRK-YYK 322
L + +FE++V + TG Q R+SY+P EI+ H F +L K Y+
Sbjct: 254 ATL-LQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEYQ 312
Query: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQLHI 353
+ F+ +V + +K + D +HI
Sbjct: 313 IKMENFDKTVPEFPTPLVSKSPNRTDLDIHI 343
>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
precursor [Homo sapiens]
Length = 490
Score = 29.3 bits (64), Expect = 6.9
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 8/78 (10%)
Query: 19 GYPPEHIIAEKRRARRRLLH--KDGSCNVYFKH--IFGEWGSYVVDIFTTLVDTKWRHMF 74
GYP HI+ E+ R + ++H G N K + G+ G + T +D ++
Sbjct: 416 GYPRSHILTEEERQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQ-NTHAID---KYSR 471
Query: 75 VIFSLSYILSWLIFGSVF 92
+IF SYI LI+ SVF
Sbjct: 472 LIFPASYIFFNLIYWSVF 489
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,312,926
Number of Sequences: 37866
Number of extensions: 621366
Number of successful extensions: 1822
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1724
Number of HSP's gapped (non-prelim): 35
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.