Guide to the Human Genome
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Search of human proteins with 253314451

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|253314451 RAD52 motif 1 isoform 6 [Homo sapiens]
         (143 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|253314451 RAD52 motif 1 isoform 6 [Homo sapiens]                   297   2e-81
gi|253314443 RAD52 motif 1 isoform 3 [Homo sapiens]                   278   1e-75
gi|253314472 RAD52 motif 1 isoform 8 [Homo sapiens]                   227   2e-60
gi|253314447 RAD52 motif 1 isoform 5 [Homo sapiens]                   227   2e-60
gi|253314453 RAD52 motif 1 isoform 7 [Homo sapiens]                   227   3e-60
gi|77873934 RAD52 motif 1 isoform 2 [Homo sapiens]                    207   2e-54
gi|21717826 RAD52 motif 1 isoform 1 [Homo sapiens]                    207   2e-54
gi|253314445 RAD52 motif 1 isoform 4 [Homo sapiens]                   207   2e-54
gi|239745785 PREDICTED: similar to hCG2007264 [Homo sapiens]           98   2e-21
gi|54607124 RNA binding motif protein 15B [Homo sapiens]               32   0.14 
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ...    27   5.8  
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ...    27   5.8  
gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo sa...    27   5.8  
gi|211059433 coiled-coil domain containing 79 [Homo sapiens]           27   7.6  
gi|34740339 dead end homolog 1 [Homo sapiens]                          27   7.6  
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]                   26   9.9  

>gi|253314451 RAD52 motif 1 isoform 6 [Homo sapiens]
          Length = 143

 Score =  297 bits (761), Expect = 2e-81
 Identities = 143/143 (100%), Positives = 143/143 (100%)

Query: 1   MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK 60
           MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK
Sbjct: 1   MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK 60

Query: 61  QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKVPCSPWKQYG 120
           QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKVPCSPWKQYG
Sbjct: 61  QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKVPCSPWKQYG 120

Query: 121 QEEEGYLSDFSLEEEEFRLPELD 143
           QEEEGYLSDFSLEEEEFRLPELD
Sbjct: 121 QEEEGYLSDFSLEEEEFRLPELD 143


>gi|253314443 RAD52 motif 1 isoform 3 [Homo sapiens]
          Length = 166

 Score =  278 bits (710), Expect = 1e-75
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 10  HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK 69
           HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK
Sbjct: 33  HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK 92

Query: 70  VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKVPCSPWKQYGQEEEGYLSD 129
           VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKVPCSPWKQYGQEEEGYLSD
Sbjct: 93  VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKVPCSPWKQYGQEEEGYLSD 152

Query: 130 FSLEEEEFRLPELD 143
           FSLEEEEFRLPELD
Sbjct: 153 FSLEEEEFRLPELD 166


>gi|253314472 RAD52 motif 1 isoform 8 [Homo sapiens]
          Length = 261

 Score =  227 bits (579), Expect = 2e-60
 Identities = 110/111 (99%), Positives = 111/111 (100%)

Query: 1   MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK 60
           MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK
Sbjct: 1   MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK 60

Query: 61  QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKV 111
           QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIK+
Sbjct: 61  QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKL 111



 Score = 77.8 bits (190), Expect = 3e-15
 Identities = 34/36 (94%), Positives = 36/36 (100%)

Query: 108 IIKVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 143
           +I+VPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD
Sbjct: 226 LIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 261


>gi|253314447 RAD52 motif 1 isoform 5 [Homo sapiens]
          Length = 228

 Score =  227 bits (579), Expect = 2e-60
 Identities = 110/111 (99%), Positives = 111/111 (100%)

Query: 1   MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK 60
           MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK
Sbjct: 1   MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK 60

Query: 61  QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKV 111
           QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIK+
Sbjct: 61  QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKL 111



 Score = 77.8 bits (190), Expect = 3e-15
 Identities = 34/36 (94%), Positives = 36/36 (100%)

Query: 108 IIKVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 143
           +I+VPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD
Sbjct: 193 LIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 228


>gi|253314453 RAD52 motif 1 isoform 7 [Homo sapiens]
          Length = 116

 Score =  227 bits (578), Expect = 3e-60
 Identities = 110/110 (100%), Positives = 110/110 (100%)

Query: 1   MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK 60
           MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK
Sbjct: 1   MHLLVPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRK 60

Query: 61  QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIK 110
           QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIK
Sbjct: 61  QLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIK 110


>gi|77873934 RAD52 motif 1 isoform 2 [Homo sapiens]
          Length = 236

 Score =  207 bits (528), Expect = 2e-54
 Identities = 101/102 (99%), Positives = 102/102 (100%)

Query: 10  HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK 69
           HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK
Sbjct: 33  HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK 92

Query: 70  VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKV 111
           VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIK+
Sbjct: 93  VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKL 134


>gi|21717826 RAD52 motif 1 isoform 1 [Homo sapiens]
          Length = 284

 Score =  207 bits (528), Expect = 2e-54
 Identities = 101/102 (99%), Positives = 102/102 (100%)

Query: 10  HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK 69
           HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK
Sbjct: 33  HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK 92

Query: 70  VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKV 111
           VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIK+
Sbjct: 93  VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKL 134



 Score = 77.8 bits (190), Expect = 3e-15
 Identities = 34/36 (94%), Positives = 36/36 (100%)

Query: 108 IIKVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 143
           +I+VPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD
Sbjct: 249 LIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 284


>gi|253314445 RAD52 motif 1 isoform 4 [Homo sapiens]
          Length = 251

 Score =  207 bits (528), Expect = 2e-54
 Identities = 101/102 (99%), Positives = 102/102 (100%)

Query: 10  HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK 69
           HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK
Sbjct: 33  HSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVK 92

Query: 70  VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKV 111
           VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIK+
Sbjct: 93  VRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKL 134



 Score = 77.8 bits (190), Expect = 3e-15
 Identities = 34/36 (94%), Positives = 36/36 (100%)

Query: 108 IIKVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 143
           +I+VPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD
Sbjct: 216 LIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD 251


>gi|239745785 PREDICTED: similar to hCG2007264 [Homo sapiens]
          Length = 175

 Score = 98.2 bits (243), Expect = 2e-21
 Identities = 50/60 (83%), Positives = 50/60 (83%)

Query: 11  SLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVKV 70
           SL  AFSQF LLYSVRVFPNAAVAH GFY VIKFYSA A H AQKAC RKQLFQ SPVKV
Sbjct: 105 SLGQAFSQFDLLYSVRVFPNAAVAHSGFYGVIKFYSAMAVHGAQKACHRKQLFQTSPVKV 164


>gi|54607124 RNA binding motif protein 15B [Homo sapiens]
          Length = 890

 Score = 32.3 bits (72), Expect = 0.14
 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 2/59 (3%)

Query: 15  AFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLG 73
           AF ++G++  V V    A    G YA +KF +   AHRA+ A   + +  ++P+K+  G
Sbjct: 356 AFEKYGIIEEV-VIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGR-VIGRNPIKIGYG 412


>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
           sapiens]
          Length = 426

 Score = 26.9 bits (58), Expect = 5.8
 Identities = 18/80 (22%), Positives = 32/80 (40%), Gaps = 3/80 (3%)

Query: 47  ARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSK 106
           AR    + +A  ++Q  +  P   R+G R        L L  S   E  +Y FG+    +
Sbjct: 119 ARVLSCSPEAMSKRQTVEDCP---RMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRR 175

Query: 107 RIIKVPCSPWKQYGQEEEGY 126
            ++ + CS  + Y      +
Sbjct: 176 GLVHLCCSKVQNYSMPTSSF 195


>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
           sapiens]
          Length = 426

 Score = 26.9 bits (58), Expect = 5.8
 Identities = 18/80 (22%), Positives = 32/80 (40%), Gaps = 3/80 (3%)

Query: 47  ARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSK 106
           AR    + +A  ++Q  +  P   R+G R        L L  S   E  +Y FG+    +
Sbjct: 119 ARVLSCSPEAMSKRQTVEDCP---RMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRR 175

Query: 107 RIIKVPCSPWKQYGQEEEGY 126
            ++ + CS  + Y      +
Sbjct: 176 GLVHLCCSKVQNYSMPTSSF 195


>gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo
           sapiens]
          Length = 1174

 Score = 26.9 bits (58), Expect = 5.8
 Identities = 17/72 (23%), Positives = 32/72 (44%), Gaps = 1/72 (1%)

Query: 5   VPPPQHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQ 64
           +P   +S+    S  G      V  N +    GF+  + FY +     ++K  D++++F+
Sbjct: 772 LPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSV-FYRSYKEQESKKGFDQEEVFE 830

Query: 65  KSPVKVRLGTRH 76
           K   +   G RH
Sbjct: 831 KPTRETCQGMRH 842


>gi|211059433 coiled-coil domain containing 79 [Homo sapiens]
          Length = 727

 Score = 26.6 bits (57), Expect = 7.6
 Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 47  ARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSK 106
           ++  H     CDR ++  ++  + +   R   + ++ + L   + Q L+N      G  K
Sbjct: 608 SKLLHSCPYQCDRHKVIVEAEDRYKSELRKSLICNKKILLTPRRRQRLSNESTTPGGIKK 667

Query: 107 RIIKVPCSPWKQYGQEEEGYL 127
           R I+      K + +EE  YL
Sbjct: 668 RRIR------KNFTEEEVNYL 682


>gi|34740339 dead end homolog 1 [Homo sapiens]
          Length = 353

 Score = 26.6 bits (57), Expect = 7.6
 Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 1/35 (2%)

Query: 22  LYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKA 56
           L   R+ P+   A PG  A++KF S RAA  A+KA
Sbjct: 165 LQEARLLPSPGPA-PGQIALLKFSSHRAAAMAKKA 198


>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
          Length = 723

 Score = 26.2 bits (56), Expect = 9.9
 Identities = 13/37 (35%), Positives = 20/37 (54%)

Query: 69  KVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCS 105
           K +   +H   Q+  L ++S K  +L +YY G NG S
Sbjct: 293 KTKAIMKHLHSQNVKLLISSVKQPDLVSYYAGVNGIS 329


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,929,272
Number of Sequences: 37866
Number of extensions: 222725
Number of successful extensions: 463
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 448
Number of HSP's gapped (non-prelim): 21
length of query: 143
length of database: 18,247,518
effective HSP length: 92
effective length of query: 51
effective length of database: 14,763,846
effective search space: 752956146
effective search space used: 752956146
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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