Guide to the Human Genome
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Search of human proteins with 251831118

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|251831118 NADH dehydrogenase subunit 6 [Homo sapiens]
         (174 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|251831118 NADH dehydrogenase subunit 6 [Homo sapiens]              350   4e-97
gi|196123590 NADH dehydrogenase subunit 6 [Homo sapiens neandert...   350   5e-97
gi|44680143 solute carrier family 23 (nucleobase transporters), ...    35   0.025
gi|44680145 solute carrier family 23 (nucleobase transporters), ...    35   0.025
gi|44680148 solute carrier family 23 (nucleobase transporters), ...    34   0.073
gi|40316845 solute carrier family 23 (nucleobase transporters), ...    34   0.073
gi|21536378 ATP-binding cassette, sub-family B (MDR/TAP), member...    31   0.62 
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa...    28   4.0  
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap...    28   4.0  
gi|239743230 PREDICTED: hypothetical protein [Homo sapiens]            28   4.0  
gi|239508907 PREDICTED: hypothetical protein [Homo sapiens]            28   4.0  
gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]           28   4.0  
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi...    28   4.0  
gi|46409657 WD repeat domain 56 [Homo sapiens]                         27   6.8  

>gi|251831118 NADH dehydrogenase subunit 6 [Homo sapiens]
          Length = 174

 Score =  350 bits (898), Expect = 4e-97
 Identities = 174/174 (100%), Positives = 174/174 (100%)

Query: 1   MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYL 60
           MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYL
Sbjct: 1   MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYL 60

Query: 61  GGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLVLWVKEYDGVVVVVNFNS 120
           GGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLVLWVKEYDGVVVVVNFNS
Sbjct: 61  GGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLVLWVKEYDGVVVVVNFNS 120

Query: 121 VGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYIVIEIARGN 174
           VGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYIVIEIARGN
Sbjct: 121 VGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYIVIEIARGN 174


>gi|196123590 NADH dehydrogenase subunit 6 [Homo sapiens
           neanderthalensis]
          Length = 174

 Score =  350 bits (897), Expect = 5e-97
 Identities = 173/174 (99%), Positives = 174/174 (100%)

Query: 1   MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYL 60
           MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYL
Sbjct: 1   MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYL 60

Query: 61  GGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLVLWVKEYDGVVVVVNFNS 120
           GGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLVLWVKEYDGVVVVVNFNS
Sbjct: 61  GGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLVLWVKEYDGVVVVVNFNS 120

Query: 121 VGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYIVIEIARGN 174
           VGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVY+VIEIARGN
Sbjct: 121 VGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYVVIEIARGN 174


>gi|44680143 solute carrier family 23 (nucleobase transporters),
           member 1 isoform b [Homo sapiens]
          Length = 602

 Score = 35.4 bits (80), Expect = 0.025
 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 9/101 (8%)

Query: 9   SVGLVMGFVG-----FSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGGM 63
           ++ LV+G +G     F+S P PI GG+   + G++  V + N     M     L  LG  
Sbjct: 409 AIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFS 468

Query: 64  MVVFGYTTAMAIEEYPEAWGSG---VEVLVSVLVGLAMEVG 101
           M  FG T    +E  P A  +G   V+ ++ VL+   M VG
Sbjct: 469 M-FFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVG 508


>gi|44680145 solute carrier family 23 (nucleobase transporters),
           member 1 isoform a [Homo sapiens]
          Length = 598

 Score = 35.4 bits (80), Expect = 0.025
 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 9/101 (8%)

Query: 9   SVGLVMGFVG-----FSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGGM 63
           ++ LV+G +G     F+S P PI GG+   + G++  V + N     M     L  LG  
Sbjct: 405 AIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFS 464

Query: 64  MVVFGYTTAMAIEEYPEAWGSG---VEVLVSVLVGLAMEVG 101
           M  FG T    +E  P A  +G   V+ ++ VL+   M VG
Sbjct: 465 M-FFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVG 504


>gi|44680148 solute carrier family 23 (nucleobase transporters),
           member 2 [Homo sapiens]
          Length = 650

 Score = 33.9 bits (76), Expect = 0.073
 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 3/100 (3%)

Query: 4   ALFLLSVGLVMGFVG-FSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGG 62
           A  +L++G++  F   F+S P P+ G L   + G++  V + N     +     L  L G
Sbjct: 463 AALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVL-G 521

Query: 63  MMVVFGYTTAMAIEEYPEAWG-SGVEVLVSVLVGLAMEVG 101
             + FG      + + P   G +G++ +++VL+  AM VG
Sbjct: 522 FSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVG 561


>gi|40316845 solute carrier family 23 (nucleobase transporters),
           member 2 [Homo sapiens]
          Length = 650

 Score = 33.9 bits (76), Expect = 0.073
 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 3/100 (3%)

Query: 4   ALFLLSVGLVMGFVG-FSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGG 62
           A  +L++G++  F   F+S P P+ G L   + G++  V + N     +     L  L G
Sbjct: 463 AALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVL-G 521

Query: 63  MMVVFGYTTAMAIEEYPEAWG-SGVEVLVSVLVGLAMEVG 101
             + FG      + + P   G +G++ +++VL+  AM VG
Sbjct: 522 FSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVG 561


>gi|21536378 ATP-binding cassette, sub-family B (MDR/TAP), member 11
           [Homo sapiens]
          Length = 1321

 Score = 30.8 bits (68), Expect = 0.62
 Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 5/60 (8%)

Query: 42  IILNFGGGYMGLMVFLIYLGGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVG 101
           I++ F  G++  ++FL Y     + F Y + + ++E     G+ V++ +SV+VG A+ +G
Sbjct: 320 IVMGFFTGFVWCLIFLCYA----LAFWYGSTLVLDEGEYTPGTLVQIFLSVIVG-ALNLG 374


>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
           sapiens]
          Length = 506

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 15/103 (14%)

Query: 8   LSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCV--IILNFGGGYMGLMVF-----LIYL 60
           L+ G + G +G           L L+ + +V  V  +++ F   YM +++F     L+  
Sbjct: 155 LNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSK 214

Query: 61  GGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLV 103
           G  M   GYT         E  GSG    V+++  +A  VGLV
Sbjct: 215 GNWMA--GYTLIT------EFVGSGSRRTVAIMYQMAFTVGLV 249


>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
           sapiens]
          Length = 554

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 15/103 (14%)

Query: 8   LSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCV--IILNFGGGYMGLMVF-----LIYL 60
           L+ G + G +G           L L+ + +V  V  +++ F   YM +++F     L+  
Sbjct: 155 LNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSK 214

Query: 61  GGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLV 103
           G  M   GYT         E  GSG    V+++  +A  VGLV
Sbjct: 215 GNWMA--GYTLIT------EFVGSGSRRTVAIMYQMAFTVGLV 249


>gi|239743230 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 331

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 22/113 (19%)

Query: 80  EAWGS----GVEVLVSVLVGLAMEVGLVLWV---------KEYDGVVVVVNFNS------ 120
           EAWG+    G E  V+VLV +   + L L++         +  DG+  V+   +      
Sbjct: 157 EAWGAPKRKGCEAAVAVLVVVLTLLLLTLFMPKPNAGFEAESVDGLAEVMGATAEVALAR 216

Query: 121 -VGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYIVIEIAR 172
            V S  +  G  +G++     GAG   D G  +++ TGW   VG  +++ + R
Sbjct: 217 PVKSGAVVVGAVAGVVVCLKKGAGKGTDAGGPMLLKTGWK--VGAVVLVVVGR 267


>gi|239508907 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 331

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 22/113 (19%)

Query: 80  EAWGS----GVEVLVSVLVGLAMEVGLVLWV---------KEYDGVVVVVNFNS------ 120
           EAWG+    G E  V+VLV +   + L L++         +  DG+  V+   +      
Sbjct: 157 EAWGAPKRKGCEAAVAVLVVVLTLLLLTLFMPKPNAGFEAESVDGLAEVMGATAEVALAR 216

Query: 121 -VGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYIVIEIAR 172
            V S  +  G  +G++     GAG   D G  +++ TGW   VG  +++ + R
Sbjct: 217 PVKSGAVVVGAVAGVVVCLKKGAGKGTDAGGPMLLKTGWK--VGAVVLVVVGR 267


>gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]
          Length = 839

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 16/76 (21%), Positives = 34/76 (44%)

Query: 41  VIILNFGGGYMGLMVFLIYLGGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEV 100
           + I++    Y   ++F   L  ++ V G++ A   +E P  +     + +S+       V
Sbjct: 715 ITIVSCNPNYRNSLLFNTSLDLLLSVVGFSFAYMGKELPTNYNEAKFITLSMTFYFTSSV 774

Query: 101 GLVLWVKEYDGVVVVV 116
            L  ++  Y GV+V +
Sbjct: 775 SLCTFMSAYSGVLVTI 790


>gi|16306555 potassium channel, subfamily K, member 13 [Homo
           sapiens]
          Length = 408

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 15/50 (30%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 10  VGLVMGFVGFS-SKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLI 58
           VG V+  +GF  + P+ + G + LI  G+VGC   + F   ++  ++ +I
Sbjct: 104 VGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFLERLITII 153


>gi|46409657 WD repeat domain 56 [Homo sapiens]
          Length = 777

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 5/58 (8%)

Query: 78  YPEAWGSGVEVLV-----SVLVGLAMEVGLVLWVKEYDGVVVVVNFNSVGSWMIYEGE 130
           Y  AWG   E ++      +++        VL  K +DG+++ V++NSV   ++  GE
Sbjct: 151 YSVAWGPDSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGE 208


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.147    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,073,668
Number of Sequences: 37866
Number of extensions: 255494
Number of successful extensions: 654
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 645
Number of HSP's gapped (non-prelim): 16
length of query: 174
length of database: 18,247,518
effective HSP length: 95
effective length of query: 79
effective length of database: 14,650,248
effective search space: 1157369592
effective search space used: 1157369592
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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