Search of human proteins with 25141325

Search of human proteins with 25141325

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25141325 nicotinamide mononucleotide adenylyltransferase 2
isoform 2 [Homo sapiens]
         (302 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25141325 nicotinamide mononucleotide adenylyltransferase 2 is...   617   e-177
gi|24307989 nicotinamide mononucleotide adenylyltransferase 2 is...   572   e-163
gi|20070321 nicotinamide mononucleotide adenylyltransferase 1 [H...   143   2e-34
gi|30039706 nicotinamide mononucleotide adenylyltransferase 3 [H...    89   4e-18
gi|189083681 paired box gene 6 isoform a [Homo sapiens]                33   0.31 
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                  33   0.31 
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                  33   0.31 
gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]            31   1.5  
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    30   2.6  
gi|89886350 Rho GTPase activating protein 11B [Homo sapiens]           30   3.4  
gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isof...    28   7.6  
gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isof...    28   7.6  
gi|4557781 alpha-N-acetylgalactosaminidase precursor [Homo sapiens]    28   7.6  
gi|28372551 bactericidal/permeability-increasing protein-like 2 ...    28   10.0 

>gi|25141325 nicotinamide mononucleotide adenylyltransferase 2
           isoform 2 [Homo sapiens]
          Length = 302

 Score =  617 bits (1590), Expect = e-177
 Identities = 302/302 (100%), Positives = 302/302 (100%)

Query: 1   MEIQELEEIQACQGLWEVFVTLSERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRH 60
           MEIQELEEIQACQGLWEVFVTLSERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRH
Sbjct: 1   MEIQELEEIQACQGLWEVFVTLSERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRH 60

Query: 61  RLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPV 120
           RLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPV
Sbjct: 61  RLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPV 120

Query: 121 IGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTV 180
           IGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTV
Sbjct: 121 IGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTV 180

Query: 181 MRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSS 240
           MRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSS
Sbjct: 181 MRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSS 240

Query: 241 ILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINA 300
           ILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINA
Sbjct: 241 ILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINA 300

Query: 301 SG 302
           SG
Sbjct: 301 SG 302


>gi|24307989 nicotinamide mononucleotide adenylyltransferase 2
           isoform 1 [Homo sapiens]
          Length = 307

 Score =  572 bits (1474), Expect = e-163
 Identities = 279/283 (98%), Positives = 281/283 (99%)

Query: 20  VTLSERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDP 79
           + + ERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDP
Sbjct: 25  IQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDP 84

Query: 80  WECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVA 139
           WECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVA
Sbjct: 85  WECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVA 144

Query: 140 TKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLL 199
           TKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLL
Sbjct: 145 TKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLL 204

Query: 200 ESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHP 259
           ESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHP
Sbjct: 205 ESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHP 264

Query: 260 MSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG 302
           MSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG
Sbjct: 265 MSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG 307


>gi|20070321 nicotinamide mononucleotide adenylyltransferase 1 [Homo
           sapiens]
          Length = 279

 Score =  143 bits (360), Expect = 2e-34
 Identities = 87/281 (30%), Positives = 144/281 (51%), Gaps = 50/281 (17%)

Query: 22  LSERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWE 81
           L E A+DY++ TGR+ V+ GI+SPV D+Y K+GL+ + HR+IM +LA +NS W+ VD WE
Sbjct: 27  LFELAKDYMNGTGRYTVVKGIISPVGDAYKKKGLIPAYHRVIMAELATKNSKWVEVDTWE 86

Query: 82  CYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATK 141
             Q  W+ T  VL HH++ ++       S+ +    +P + +P  +              
Sbjct: 87  SLQKEWKETLKVLRHHQEKLE------ASDCDHQQNSPTLERPGRK-------------- 126

Query: 142 PTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLLES 201
                                    ++T   +++   ++    +   ++ LLCG+DLLES
Sbjct: 127 ------------------------RKWTETQDSSQKKSLEPKTKAVPKVKLLCGADLLES 162

Query: 202 FCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMS 261
           F +P LW   D+  IV ++G++ V R   D  + +  S +L K+++NI VV + I +   
Sbjct: 163 FAVPNLWKSEDITQIVANYGLICVTRAGNDAQKFIYESDVLWKHRSNIHVVNEWIAND-- 220

Query: 262 VVSSTKSRLALQHGDGHVVDYLSQPVI-DYILKSQLYINAS 301
            +SSTK R AL+ G    + YL   ++ +YI K  LY + S
Sbjct: 221 -ISSTKIRRALRRGQS--IRYLVPDLVQEYIEKHNLYSSES 258


>gi|30039706 nicotinamide mononucleotide adenylyltransferase 3 [Homo
           sapiens]
          Length = 215

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 81/265 (30%), Positives = 110/265 (41%), Gaps = 69/265 (26%)

Query: 38  VIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHH 97
           VI GI+SPV+D+YGK+ L +S HR+ M +LA+Q SDWIRVDPWE  Q  W  T  VL HH
Sbjct: 4   VIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHH 63

Query: 98  RDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSR 157
              + R                    PQ E P        + + P A   L        +
Sbjct: 64  HSKLLR------------------SPPQMEGPD---HGKALFSTPAAVPEL--------K 94

Query: 158 ICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIV 217
           + C    ++ F    +  NL      +EI            +E F               
Sbjct: 95  LLCGADVLKTF----QTPNLWKDAHIQEI------------VEKF--------------- 123

Query: 218 GDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDG 277
              G+V V R   D    +  S ILR +++NI + K+ + +    +S+T  R AL  G G
Sbjct: 124 ---GLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNE---ISATYIRRAL--GQG 175

Query: 278 HVVDYL-SQPVIDYILKSQLYINAS 301
             V YL    VI YI    LY   S
Sbjct: 176 QSVKYLIPDAVITYIKDHGLYTKGS 200


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 33.1 bits (74), Expect = 0.31
 Identities = 17/60 (28%), Positives = 27/60 (45%)

Query: 113 NTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVD 172
           NTPS  P+         QPI Q +   +  T+  +LG+   +L+      PP+  FT  +
Sbjct: 280 NTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMAN 339


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score = 33.1 bits (74), Expect = 0.31
 Identities = 17/60 (28%), Positives = 27/60 (45%)

Query: 113 NTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVD 172
           NTPS  P+         QPI Q +   +  T+  +LG+   +L+      PP+  FT  +
Sbjct: 294 NTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMAN 353


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 33.1 bits (74), Expect = 0.31
 Identities = 17/60 (28%), Positives = 27/60 (45%)

Query: 113 NTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVD 172
           NTPS  P+         QPI Q +   +  T+  +LG+   +L+      PP+  FT  +
Sbjct: 280 NTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMAN 339


>gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]
          Length = 511

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 11/85 (12%)

Query: 87  WQTTC-SVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATK--PT 143
           WQ TC   ++    +M      ++  + TP+ TPV G PQ     P+ + SNV  K   T
Sbjct: 225 WQETCVDAIKVPEKIMN-----MIEEIKTPASTPVSGTPQ---ASPMIERSNVVRKDYDT 276

Query: 144 AAKILGKVGESLSRICCVRPPVERF 168
            +K   K+  + S      P ++ F
Sbjct: 277 LSKCSPKMPPAPSGRAYTSPLIDMF 301


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 99   DLMKRVTG--CILSNVNTPSMTPVIGQPQNETPQPIYQNS 136
            D+M  V+G    +SN  T S+   I QPQ  TP PI   S
Sbjct: 1025 DIMAAVSGRASAMSNTPTHSIAASISQPQTPTPSPIISPS 1064


>gi|89886350 Rho GTPase activating protein 11B [Homo sapiens]
          Length = 267

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 13/33 (39%), Positives = 18/33 (54%)

Query: 80  WECYQDTWQTTCSVLEHHRDLMKRVTGCILSNV 112
           W+ YQ  W    SVL HH   +K+V   +L N+
Sbjct: 228 WKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNI 260


>gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isoform
           b [Homo sapiens]
          Length = 867

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 5/66 (7%)

Query: 41  GIVSPVH--DSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWE---CYQDTWQTTCSVLE 95
           G+V  +H  D +GK  LV+   R     L   N  ++RVD  +     +D    T  + E
Sbjct: 266 GVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKE 325

Query: 96  HHRDLM 101
           H +D++
Sbjct: 326 HDQDVL 331


>gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isoform
           a [Homo sapiens]
          Length = 1011

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 5/66 (7%)

Query: 41  GIVSPVH--DSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWE---CYQDTWQTTCSVLE 95
           G+V  +H  D +GK  LV+   R     L   N  ++RVD  +     +D    T  + E
Sbjct: 410 GVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKE 469

Query: 96  HHRDLM 101
           H +D++
Sbjct: 470 HDQDVL 475


>gi|4557781 alpha-N-acetylgalactosaminidase precursor [Homo sapiens]
          Length = 411

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 11/26 (42%), Positives = 19/26 (73%), Gaps = 1/26 (3%)

Query: 197 DLLESFCIPGLWNEADMEVIVGDFGI 222
           D+L+    PG WN+ DM +++G+FG+
Sbjct: 237 DILQPVAGPGHWNDPDM-LLIGNFGL 261


>gi|28372551 bactericidal/permeability-increasing protein-like 2
           [Homo sapiens]
          Length = 507

 Score = 28.1 bits (61), Expect = 10.0
 Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 14/116 (12%)

Query: 112 VNTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFV 171
           ++ P+   ++ QP+N T + I     VA+      ILG+       +C +     R    
Sbjct: 358 LDIPASIMMLTQPKNSTVETIVSMDFVASTSVGLVILGQ-----RLVCSLSLNRFRLALP 412

Query: 172 DENANLGTVMRYEEI-----ELRILLLCGSDLLESFCIPG----LWNEADMEVIVG 218
           + N +   V+R+E I        +L L  + L + F +      L+  +D+EV+ G
Sbjct: 413 ESNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLSNPHKFLFVNSDIEVLEG 468


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,391,127
Number of Sequences: 37866
Number of extensions: 488295
Number of successful extensions: 1032
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1021
Number of HSP's gapped (non-prelim): 16
length of query: 302
length of database: 18,247,518
effective HSP length: 102
effective length of query: 200
effective length of database: 14,385,186
effective search space: 2877037200
effective search space used: 2877037200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.