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Search of human proteins with 24497438
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24497438 interleukin 12B precursor [Homo sapiens]
(328 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24497438 interleukin 12B precursor [Homo sapiens] 681 0.0
gi|22212918 ciliary neurotrophic factor receptor preproprotein [... 67 2e-11
gi|4502931 ciliary neurotrophic factor receptor preproprotein [H... 67 2e-11
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi... 65 8e-11
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap... 65 8e-11
gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens] 51 1e-06
gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor ... 50 3e-06
gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor [... 50 3e-06
gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [H... 50 3e-06
gi|9624969 butyrophilin-like 2 [Homo sapiens] 39 0.008
gi|24430212 interleukin 23 receptor precursor [Homo sapiens] 36 0.041
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 35 0.070
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 35 0.070
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 35 0.070
gi|50511928 Fc fragment of IgG, low affinity IIb, receptor isofo... 35 0.091
gi|50511932 Fc fragment of IgG, low affinity IIb, receptor isofo... 35 0.091
gi|50726979 Fc fragment of IgG, low affinity IIIa, receptor (CD1... 35 0.12
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 34 0.16
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 34 0.16
gi|189083840 Fc fragment of IgG, low affinity IIIa, receptor (CD... 34 0.20
gi|189083838 Fc fragment of IgG, low affinity IIIa, receptor (CD... 34 0.20
gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo... 34 0.20
gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo... 34 0.20
gi|224591419 zinc finger and BTB domain containing 8B [Homo sapi... 33 0.27
gi|126116592 Fc fragment of IgG, low affinity IIc, receptor [Hom... 33 0.27
gi|132814489 low affinity immunoglobulin gamma Fc region recepto... 33 0.27
gi|50511926 Fc fragment of IgG, low affinity IIb, receptor isofo... 33 0.27
gi|50511930 Fc fragment of IgG, low affinity IIb, receptor isofo... 33 0.27
gi|118572606 hemicentin 1 [Homo sapiens] 33 0.27
gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens] 33 0.45
>gi|24497438 interleukin 12B precursor [Homo sapiens]
Length = 328
Score = 681 bits (1758), Expect = 0.0
Identities = 328/328 (100%), Positives = 328/328 (100%)
Query: 1 MCHQQLVISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITW 60
MCHQQLVISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITW
Sbjct: 1 MCHQQLVISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITW 60
Query: 61 TLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQ 120
TLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQ
Sbjct: 61 TLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQ 120
Query: 121 KEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERV 180
KEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERV
Sbjct: 121 KEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERV 180
Query: 181 RGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKN 240
RGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKN
Sbjct: 181 RGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKN 240
Query: 241 LQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVIC 300
LQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVIC
Sbjct: 241 LQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVIC 300
Query: 301 RKNASISVRAQDRYYSSSWSEWASVPCS 328
RKNASISVRAQDRYYSSSWSEWASVPCS
Sbjct: 301 RKNASISVRAQDRYYSSSWSEWASVPCS 328
>gi|22212918 ciliary neurotrophic factor receptor preproprotein
[Homo sapiens]
Length = 372
Score = 67.0 bits (162), Expect = 2e-11
Identities = 74/300 (24%), Positives = 120/300 (40%), Gaps = 63/300 (21%)
Query: 43 GEMVVLTCDTPEEDG-ITWTL---DQSSEVLGSGKTLTIQVKEFGDAGQYTC-HKGGEVL 97
G V L C T D +TW + D + ++L +G L + E G +G Y C H+ L
Sbjct: 39 GSDVTLPCGTANWDAAVTWRVNGTDLAPDLL-NGSQLVLHGLELGHSGLYACFHRDSWHL 97
Query: 98 SHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL--TFS 155
H +LL G+ P + L C + Y F C W T + TF+
Sbjct: 98 RHQVLL----HVGL-----------PPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFN 142
Query: 156 VKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAA--------EESLP 207
V GS + C++D A ++
Sbjct: 143 VTVLHGSK--------------------------IMVCEKDPALKNRCHIRYMHLFSTIK 176
Query: 208 IEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWSTPH 266
+V + + L + +F I+KPDPP+N+ +P+ N R++EV+W+ P TW P
Sbjct: 177 YKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPE 236
Query: 267 SYFSLTFCVQVQGKSKREKKDRVFTDKTSATV---ICRKNASISVRAQDRYYSSSWSEWA 323
S F L F ++ + + + +D T+ T+ K I V A+D +WS+W+
Sbjct: 237 S-FPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEI-GTWSDWS 294
>gi|4502931 ciliary neurotrophic factor receptor preproprotein [Homo
sapiens]
Length = 372
Score = 67.0 bits (162), Expect = 2e-11
Identities = 74/300 (24%), Positives = 120/300 (40%), Gaps = 63/300 (21%)
Query: 43 GEMVVLTCDTPEEDG-ITWTL---DQSSEVLGSGKTLTIQVKEFGDAGQYTC-HKGGEVL 97
G V L C T D +TW + D + ++L +G L + E G +G Y C H+ L
Sbjct: 39 GSDVTLPCGTANWDAAVTWRVNGTDLAPDLL-NGSQLVLHGLELGHSGLYACFHRDSWHL 97
Query: 98 SHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL--TFS 155
H +LL G+ P + L C + Y F C W T + TF+
Sbjct: 98 RHQVLL----HVGL-----------PPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFN 142
Query: 156 VKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAA--------EESLP 207
V GS + C++D A ++
Sbjct: 143 VTVLHGSK--------------------------IMVCEKDPALKNRCHIRYMHLFSTIK 176
Query: 208 IEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWSTPH 266
+V + + L + +F I+KPDPP+N+ +P+ N R++EV+W+ P TW P
Sbjct: 177 YKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPE 236
Query: 267 SYFSLTFCVQVQGKSKREKKDRVFTDKTSATV---ICRKNASISVRAQDRYYSSSWSEWA 323
S F L F ++ + + + +D T+ T+ K I V A+D +WS+W+
Sbjct: 237 S-FPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEI-GTWSDWS 294
>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
sapiens]
Length = 468
Score = 65.1 bits (157), Expect = 8e-11
Identities = 77/329 (23%), Positives = 128/329 (38%), Gaps = 55/329 (16%)
Query: 16 LASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPE-EDGIT--WTL------DQSS 66
LA+P A+ + V PG+ V LTC E ED T W L S
Sbjct: 13 LAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPS 72
Query: 67 EVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNK 126
G G+ L ++ + D+G Y+C++ G LL+ D+ P +
Sbjct: 73 RWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLV----------DV------PPEE 116
Query: 127 TFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKE 186
L C K+ C W G +T A L + ++
Sbjct: 117 PQLSCFRKSPLSNVVCEW----------------GPRSTPSLTTKAVLLVRKFQNSPAED 160
Query: 187 Y----EYSVECQEDS---ACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPK 239
+ +YS E Q+ S A P + S I M A + T +F I++PDPP
Sbjct: 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPA 220
Query: 240 NLQLKPL-KNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATV 298
N+ + + +N R + V+W+ P +W++ S++ L F ++ + + + + D V
Sbjct: 221 NITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRFELRYRAERSKTFTTWMVKDLQHHCV 278
Query: 299 I----CRKNASISVRAQDRYYSSSWSEWA 323
I + +RAQ+ + WSEW+
Sbjct: 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWS 307
>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
sapiens]
Length = 365
Score = 65.1 bits (157), Expect = 8e-11
Identities = 77/329 (23%), Positives = 128/329 (38%), Gaps = 55/329 (16%)
Query: 16 LASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPE-EDGIT--WTL------DQSS 66
LA+P A+ + V PG+ V LTC E ED T W L S
Sbjct: 13 LAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPS 72
Query: 67 EVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNK 126
G G+ L ++ + D+G Y+C++ G LL+ D+ P +
Sbjct: 73 RWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLV----------DV------PPEE 116
Query: 127 TFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKE 186
L C K+ C W G +T A L + ++
Sbjct: 117 PQLSCFRKSPLSNVVCEW----------------GPRSTPSLTTKAVLLVRKFQNSPAED 160
Query: 187 Y----EYSVECQEDS---ACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPK 239
+ +YS E Q+ S A P + S I M A + T +F I++PDPP
Sbjct: 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPA 220
Query: 240 NLQLKPL-KNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATV 298
N+ + + +N R + V+W+ P +W++ S++ L F ++ + + + + D V
Sbjct: 221 NITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRFELRYRAERSKTFTTWMVKDLQHHCV 278
Query: 299 I----CRKNASISVRAQDRYYSSSWSEWA 323
I + +RAQ+ + WSEW+
Sbjct: 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWS 307
>gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens]
Length = 229
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/120 (31%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 207 PIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPH 266
P + V AVH + F IIKPDPP+ ++L PL RQ++V WE P +W P
Sbjct: 101 PYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLA-ERQLQVQWEPPGSWPFP- 158
Query: 267 SYFSLTFCVQV--QGKSKREKKDRV-FTDKTSATVICRKNASISVRAQDRYYSSSWSEWA 323
FSL + ++ QG ++ + + T V R + V AQD S+W+
Sbjct: 159 EIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWS 218
>gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor
[Homo sapiens]
Length = 422
Score = 50.1 bits (118), Expect = 3e-06
Identities = 64/306 (20%), Positives = 107/306 (34%), Gaps = 61/306 (19%)
Query: 42 PGEMVVLTCD-TPEEDGITWTLDQSSEVL-----GSGKTLTIQVKEFGDAGQYTCHKGGE 95
PG V L C D ++W D ++L G G L + + D G Y C
Sbjct: 40 PGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGPDSGLGHELVLAQADSTDEGTYIC----- 94
Query: 96 VLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWW----------- 144
+ DG + P + + C+A +Y F+C W
Sbjct: 95 ----------QTLDGALGGTVTLQLGYPPARPVVSCQAADYEN-FSCTWSPSQISGLPTR 143
Query: 145 -LTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAER--VRGDNKEYEYSVECQEDSACPA 201
LT+ S R S C L A R V G +Y + E + A
Sbjct: 144 YLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGA 203
Query: 202 AEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKN-SRQVEVSWEYPD 260
+ L + ++ I++PDPP+ L+++ + R++ SW YP
Sbjct: 204 STRLLDVS-------------------LQSILRPDPPQGLRVESVPGYPRRLRASWTYPA 244
Query: 261 TW-STPHSYFSLTFCVQVQGKSKR--EKKDRVFTDKTSATVICRKNASISVRAQDRYYSS 317
+W PH F L F +Q + + ++ + ++ V A+D +
Sbjct: 245 SWPCQPH--FLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAG 302
Query: 318 SWSEWA 323
+WS W+
Sbjct: 303 TWSTWS 308
>gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor
[Homo sapiens]
Length = 390
Score = 50.1 bits (118), Expect = 3e-06
Identities = 64/306 (20%), Positives = 107/306 (34%), Gaps = 61/306 (19%)
Query: 42 PGEMVVLTCD-TPEEDGITWTLDQSSEVL-----GSGKTLTIQVKEFGDAGQYTCHKGGE 95
PG V L C D ++W D ++L G G L + + D G Y C
Sbjct: 40 PGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGPDSGLGHELVLAQADSTDEGTYIC----- 94
Query: 96 VLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWW----------- 144
+ DG + P + + C+A +Y F+C W
Sbjct: 95 ----------QTLDGALGGTVTLQLGYPPARPVVSCQAADYEN-FSCTWSPSQISGLPTR 143
Query: 145 -LTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAER--VRGDNKEYEYSVECQEDSACPA 201
LT+ S R S C L A R V G +Y + E + A
Sbjct: 144 YLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGA 203
Query: 202 AEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKN-SRQVEVSWEYPD 260
+ L + ++ I++PDPP+ L+++ + R++ SW YP
Sbjct: 204 STRLLDVS-------------------LQSILRPDPPQGLRVESVPGYPRRLRASWTYPA 244
Query: 261 TW-STPHSYFSLTFCVQVQGKSKR--EKKDRVFTDKTSATVICRKNASISVRAQDRYYSS 317
+W PH F L F +Q + + ++ + ++ V A+D +
Sbjct: 245 SWPCQPH--FLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAG 302
Query: 318 SWSEWA 323
+WS W+
Sbjct: 303 TWSTWS 308
>gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 422
Score = 50.1 bits (118), Expect = 3e-06
Identities = 64/306 (20%), Positives = 107/306 (34%), Gaps = 61/306 (19%)
Query: 42 PGEMVVLTCD-TPEEDGITWTLDQSSEVL-----GSGKTLTIQVKEFGDAGQYTCHKGGE 95
PG V L C D ++W D ++L G G L + + D G Y C
Sbjct: 40 PGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGPDSGLGHELVLAQADSTDEGTYIC----- 94
Query: 96 VLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWW----------- 144
+ DG + P + + C+A +Y F+C W
Sbjct: 95 ----------QTLDGALGGTVTLQLGYPPARPVVSCQAADYEN-FSCTWSPSQISGLPTR 143
Query: 145 -LTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAER--VRGDNKEYEYSVECQEDSACPA 201
LT+ S R S C L A R V G +Y + E + A
Sbjct: 144 YLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGA 203
Query: 202 AEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKN-SRQVEVSWEYPD 260
+ L + ++ I++PDPP+ L+++ + R++ SW YP
Sbjct: 204 STRLLDVS-------------------LQSILRPDPPQGLRVESVPGYPRRLRASWTYPA 244
Query: 261 TW-STPHSYFSLTFCVQVQGKSKR--EKKDRVFTDKTSATVICRKNASISVRAQDRYYSS 317
+W PH F L F +Q + + ++ + ++ V A+D +
Sbjct: 245 SWPCQPH--FLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAG 302
Query: 318 SWSEWA 323
+WS W+
Sbjct: 303 TWSTWS 308
>gi|9624969 butyrophilin-like 2 [Homo sapiens]
Length = 455
Score = 38.5 bits (88), Expect = 0.008
Identities = 57/253 (22%), Positives = 91/253 (35%), Gaps = 24/253 (9%)
Query: 27 KKDVYVVELDWYPDAPGEMVVLTCDTPE------EDGITWTLDQSSEVLGSGKTLTIQVK 80
K+ VE+ WY P V + D E E+ W + + L I
Sbjct: 55 KRTTMHVEVRWYRSEPSTPVFVHRDGVEVTEMQMEEYRGWVEWIENGIAKGNVALKIHNI 114
Query: 81 EFGDAGQYTCH-KGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGR 139
+ D GQY CH + G + LLL K G+ S + + ++ L C A+ +
Sbjct: 115 QPSDNGQYWCHFQDGNYCGETSLLL--KVAGLGSAPSIHMEGPGESGVQLVCTARGWFPE 172
Query: 140 FTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSAC 199
+W I + +V R D G+ ATL + SV C +
Sbjct: 173 PQVYW-EDIRGEKLLAVSEHR-IQDKDGLFYAEATLVVRNASAE------SVSCLVHNPV 224
Query: 200 PAAEE----SLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVS 255
E+ SLP ++ + LK + +R + D L P N++ +EV
Sbjct: 225 LTEEKGSVISLPEKLQTELA-SLKVNGPSQPILVR--VGEDIQLTCYLSPKANAQSMEVR 281
Query: 256 WEYPDTWSTPHSY 268
W+ + H Y
Sbjct: 282 WDRSHRYPAVHVY 294
>gi|24430212 interleukin 23 receptor precursor [Homo sapiens]
Length = 629
Score = 36.2 bits (82), Expect = 0.041
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 8/89 (8%)
Query: 131 CEAKNYSGRFTCWW----LTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKE 186
C YSG TC W LT I T VKS + Q +T +S + ++G K
Sbjct: 133 CVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYINISTDSLQGGKK- 191
Query: 187 YEYSVECQEDSACPAAEESLPIEVMVDAV 215
Y V Q +A EES +++ +D +
Sbjct: 192 --YLVWVQAANAL-GMEESKQLQIHLDDI 217
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 35.4 bits (80), Expect = 0.070
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Query: 42 PGEMVVLTCDTPE---------EDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
PGE+V + C +DG+ L Q + + GSG TL I + DAG +TC
Sbjct: 2136 PGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTC 2193
Score = 32.7 bits (73), Expect = 0.45
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 9/57 (15%)
Query: 43 GEMVVLTCDTPE--EDGITWTLD-------QSSEVLGSGKTLTIQVKEFGDAGQYTC 90
G+ VL+C+T E +TW D Q ++ L G+ L IQ + D G Y+C
Sbjct: 1856 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSC 1912
Score = 30.4 bits (67), Expect = 2.3
Identities = 14/36 (38%), Positives = 20/36 (55%)
Query: 55 EDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
+DG T +VLG G+ L IQ + D+G+Y C
Sbjct: 1484 KDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLC 1519
Score = 29.6 bits (65), Expect = 3.8
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
Query: 34 ELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
EL P AP E++ TP+ + ITW D + + +V DAG YTC
Sbjct: 2313 ELSLTPGAPMELLCDAQGTPQPN-ITWHKDGQALTRLENNSRATRVLRVRDAGLYTC 2368
Score = 28.9 bits (63), Expect = 6.6
Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 16/97 (16%)
Query: 11 FSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDG--ITWTLDQS--- 65
F+L P++ E + DV VV G +V L C+ ++W D
Sbjct: 2206 FTLQVQVPPVLEPVEFQNDVVVVR--------GSLVELPCEARGVPLPLVSWMKDGEPLL 2257
Query: 66 SEVLGSGKTLTIQVKEFGDAGQYTC---HKGGEVLSH 99
S+ L G +L ++ GD+G Y+C + GE H
Sbjct: 2258 SQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 2294
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 35.4 bits (80), Expect = 0.070
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Query: 42 PGEMVVLTCDTPE---------EDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
PGE+V + C +DG+ L Q + + GSG TL I + DAG +TC
Sbjct: 3327 PGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTC 3384
Score = 32.7 bits (73), Expect = 0.45
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 9/57 (15%)
Query: 43 GEMVVLTCDTPE--EDGITWTLD-------QSSEVLGSGKTLTIQVKEFGDAGQYTC 90
G+ VL+C+T E +TW D Q ++ L G+ L IQ + D G Y+C
Sbjct: 3047 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSC 3103
Score = 30.4 bits (67), Expect = 2.3
Identities = 14/36 (38%), Positives = 20/36 (55%)
Query: 55 EDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
+DG T +VLG G+ L IQ + D+G+Y C
Sbjct: 2675 KDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLC 2710
Score = 29.6 bits (65), Expect = 3.8
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
Query: 34 ELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
EL P AP E++ TP+ + ITW D + + +V DAG YTC
Sbjct: 3504 ELSLTPGAPMELLCDAQGTPQPN-ITWHKDGQALTRLENNSRATRVLRVRDAGLYTC 3559
Score = 28.9 bits (63), Expect = 6.6
Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 16/97 (16%)
Query: 11 FSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDG--ITWTLDQS--- 65
F+L P++ E + DV VV G +V L C+ ++W D
Sbjct: 3397 FTLQVQVPPVLEPVEFQNDVVVVR--------GSLVELPCEARGVPLPLVSWMKDGEPLL 3448
Query: 66 SEVLGSGKTLTIQVKEFGDAGQYTC---HKGGEVLSH 99
S+ L G +L ++ GD+G Y+C + GE H
Sbjct: 3449 SQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 3485
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 35.4 bits (80), Expect = 0.070
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Query: 42 PGEMVVLTCDTPE---------EDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
PGE+V + C +DG+ L Q + + GSG TL I + DAG +TC
Sbjct: 2045 PGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTC 2102
Score = 32.7 bits (73), Expect = 0.45
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 9/57 (15%)
Query: 43 GEMVVLTCDTPE--EDGITWTLD-------QSSEVLGSGKTLTIQVKEFGDAGQYTC 90
G+ VL+C+T E +TW D Q ++ L G+ L IQ + D G Y+C
Sbjct: 1765 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSC 1821
Score = 30.4 bits (67), Expect = 2.3
Identities = 14/36 (38%), Positives = 20/36 (55%)
Query: 55 EDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
+DG T +VLG G+ L IQ + D+G+Y C
Sbjct: 1393 KDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLC 1428
Score = 29.6 bits (65), Expect = 3.8
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
Query: 34 ELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
EL P AP E++ TP+ + ITW D + + +V DAG YTC
Sbjct: 2222 ELSLTPGAPMELLCDAQGTPQPN-ITWHKDGQALTRLENNSRATRVLRVRDAGLYTC 2277
Score = 28.9 bits (63), Expect = 6.6
Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 16/97 (16%)
Query: 11 FSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDG--ITWTLDQS--- 65
F+L P++ E + DV VV G +V L C+ ++W D
Sbjct: 2115 FTLQVQVPPVLEPVEFQNDVVVVR--------GSLVELPCEARGVPLPLVSWMKDGEPLL 2166
Query: 66 SEVLGSGKTLTIQVKEFGDAGQYTC---HKGGEVLSH 99
S+ L G +L ++ GD+G Y+C + GE H
Sbjct: 2167 SQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 2203
>gi|50511928 Fc fragment of IgG, low affinity IIb, receptor isoform
4 [Homo sapiens]
Length = 309
Score = 35.0 bits (79), Expect = 0.091
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 7/130 (5%)
Query: 7 VISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTC---DTPEEDGITWTLD 63
++ W +++FLA P+ K V +E W + V LTC +PE D I W +
Sbjct: 28 MLLWTAVLFLA-PVAGTPAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 86
Query: 64 QSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEP 123
+ + + + D+G+YTC G LS + L E + T L+ Q+
Sbjct: 87 GNLIPTHTQPSYRFKANN-NDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQE-- 143
Query: 124 KNKTFLRCEA 133
LRC +
Sbjct: 144 GETIVLRCHS 153
>gi|50511932 Fc fragment of IgG, low affinity IIb, receptor isoform
2 [Homo sapiens]
Length = 290
Score = 35.0 bits (79), Expect = 0.091
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 7/130 (5%)
Query: 7 VISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTC---DTPEEDGITWTLD 63
++ W +++FLA P+ K V +E W + V LTC +PE D I W +
Sbjct: 28 MLLWTAVLFLA-PVAGTPAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 86
Query: 64 QSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEP 123
+ + + + D+G+YTC G LS + L E + T L+ Q+
Sbjct: 87 GNLIPTHTQPSYRFKANN-NDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQE-- 143
Query: 124 KNKTFLRCEA 133
LRC +
Sbjct: 144 GETIVLRCHS 153
>gi|50726979 Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
isoform a precursor [Homo sapiens]
Length = 290
Score = 34.7 bits (78), Expect = 0.12
Identities = 28/110 (25%), Positives = 42/110 (38%), Gaps = 9/110 (8%)
Query: 2 CHQQLVISW-----FSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCD---TP 53
C Q I W +L+ L S + +L K V +E WY + V L C +P
Sbjct: 30 CPLQCGIMWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSP 89
Query: 54 EEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLL 103
E++ W S + + I D+G+Y C LS + L
Sbjct: 90 EDNSTQW-FHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQL 138
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 34.3 bits (77), Expect = 0.16
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 10/75 (13%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G +L+C+ + + +TW D EV G + L +Q DAG+Y+C
Sbjct: 1181 GTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240
Query: 93 GGEVLSHSLLLLHKK 107
GG+ +S L + K
Sbjct: 1241 GGQRVSFQLHITEPK 1255
Score = 34.3 bits (77), Expect = 0.16
Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 10/69 (14%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G L+C+ + + +TW D E G + L +Q DAG+YTC
Sbjct: 1273 GASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Query: 93 GGEVLSHSL 101
GG+ LS L
Sbjct: 1333 GGQRLSFHL 1341
Score = 34.3 bits (77), Expect = 0.16
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 10/69 (14%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G + L+C+ + + +TW D E +G + L +Q D G+Y+C
Sbjct: 1365 GAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 1424
Query: 93 GGEVLSHSL 101
GG+ LS SL
Sbjct: 1425 GGQRLSFSL 1433
Score = 33.9 bits (76), Expect = 0.20
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 10/69 (14%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G L+C+ + + +TW D E +G + L +Q DAG+Y+C
Sbjct: 1641 GASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA 1700
Query: 93 GGEVLSHSL 101
GG+ LS L
Sbjct: 1701 GGQRLSFRL 1709
Score = 33.1 bits (74), Expect = 0.35
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 10/69 (14%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G L+C+ + + +TW D E G + L +Q DAG+Y+C
Sbjct: 905 GASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Query: 93 GGEVLSHSL 101
GG+ LS L
Sbjct: 965 GGQRLSFHL 973
Score = 31.6 bits (70), Expect = 1.0
Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 10/75 (13%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G +L+C+ + + +TW D EV G + L + DAG+Y+C
Sbjct: 1089 GASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148
Query: 93 GGEVLSHSLLLLHKK 107
GG+ +S L + K
Sbjct: 1149 GGQRVSFHLHITEPK 1163
Score = 31.2 bits (69), Expect = 1.3
Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 10/75 (13%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G L+C+ + + +TW D E +G + L +Q DAG+Y+C
Sbjct: 1549 GTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA 1608
Query: 93 GGEVLSHSLLLLHKK 107
G + LS L + K
Sbjct: 1609 GDQRLSFHLHVAEPK 1623
Score = 30.0 bits (66), Expect = 2.9
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 14/112 (12%)
Query: 41 APGEMVVLTCDTPEEDG-ITWTLD-------QSSEVL--GSGKTLTIQVKEFGDAGQYTC 90
APGE V L C+ + W D Q +V+ G+ L I+ DAG+YTC
Sbjct: 2839 APGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTC 2898
Query: 91 HKGGEVLSHSLLLLHKKEDGIWSTDILKD-QKEPKNKTFLRCEAKNYSGRFT 141
S S LH +E T+ L + Q E K C+ ++ + T
Sbjct: 2899 EVEA---SKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVT 2947
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 34.3 bits (77), Expect = 0.16
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 10/75 (13%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G +L+C+ + + +TW D EV G + L +Q DAG+Y+C
Sbjct: 1181 GTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240
Query: 93 GGEVLSHSLLLLHKK 107
GG+ +S L + K
Sbjct: 1241 GGQRVSFQLHITEPK 1255
Score = 34.3 bits (77), Expect = 0.16
Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 10/69 (14%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G L+C+ + + +TW D E G + L +Q DAG+YTC
Sbjct: 1273 GASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Query: 93 GGEVLSHSL 101
GG+ LS L
Sbjct: 1333 GGQRLSFHL 1341
Score = 34.3 bits (77), Expect = 0.16
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 10/69 (14%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G + L+C+ + + +TW D E +G + L +Q D G+Y+C
Sbjct: 1365 GAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 1424
Query: 93 GGEVLSHSL 101
GG+ LS SL
Sbjct: 1425 GGQRLSFSL 1433
Score = 33.9 bits (76), Expect = 0.20
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 10/69 (14%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G L+C+ + + +TW D E +G + L +Q DAG+Y+C
Sbjct: 1641 GASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA 1700
Query: 93 GGEVLSHSL 101
GG+ LS L
Sbjct: 1701 GGQRLSFRL 1709
Score = 33.1 bits (74), Expect = 0.35
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 10/69 (14%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G L+C+ + + +TW D E G + L +Q DAG+Y+C
Sbjct: 905 GASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Query: 93 GGEVLSHSL 101
GG+ LS L
Sbjct: 965 GGQRLSFHL 973
Score = 31.6 bits (70), Expect = 1.0
Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 10/75 (13%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G +L+C+ + + +TW D EV G + L + DAG+Y+C
Sbjct: 1089 GASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148
Query: 93 GGEVLSHSLLLLHKK 107
GG+ +S L + K
Sbjct: 1149 GGQRVSFHLHITEPK 1163
Score = 31.2 bits (69), Expect = 1.3
Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 10/75 (13%)
Query: 43 GEMVVLTCDTPE-EDGITWTLDQSS---------EVLGSGKTLTIQVKEFGDAGQYTCHK 92
G L+C+ + + +TW D E +G + L +Q DAG+Y+C
Sbjct: 1549 GTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA 1608
Query: 93 GGEVLSHSLLLLHKK 107
G + LS L + K
Sbjct: 1609 GDQRLSFHLHVAEPK 1623
Score = 30.0 bits (66), Expect = 2.9
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 14/112 (12%)
Query: 41 APGEMVVLTCDTPEEDG-ITWTLD-------QSSEVL--GSGKTLTIQVKEFGDAGQYTC 90
APGE V L C+ + W D Q +V+ G+ L I+ DAG+YTC
Sbjct: 2839 APGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTC 2898
Query: 91 HKGGEVLSHSLLLLHKKEDGIWSTDILKD-QKEPKNKTFLRCEAKNYSGRFT 141
S S LH +E T+ L + Q E K C+ ++ + T
Sbjct: 2899 EVEA---SKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVT 2947
>gi|189083840 Fc fragment of IgG, low affinity IIIa, receptor
(CD16a) isoform c precursor [Homo sapiens]
Length = 254
Score = 33.9 bits (76), Expect = 0.20
Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 4/95 (4%)
Query: 12 SLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCD---TPEEDGITWTLDQSSEV 68
+L+ L S + +L K V +E WY + V L C +PE++ W S +
Sbjct: 9 ALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQW-FHNESLI 67
Query: 69 LGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLL 103
+ I D+G+Y C LS + L
Sbjct: 68 SSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQL 102
>gi|189083838 Fc fragment of IgG, low affinity IIIa, receptor
(CD16a) isoform c precursor [Homo sapiens]
Length = 254
Score = 33.9 bits (76), Expect = 0.20
Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 4/95 (4%)
Query: 12 SLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCD---TPEEDGITWTLDQSSEV 68
+L+ L S + +L K V +E WY + V L C +PE++ W S +
Sbjct: 9 ALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQW-FHNESLI 67
Query: 69 LGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLL 103
+ I D+G+Y C LS + L
Sbjct: 68 SSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQL 102
>gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo
sapiens]
Length = 1214
Score = 33.9 bits (76), Expect = 0.20
Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 12/100 (12%)
Query: 37 WY----PDAPGEMVVLTCDTP--------EEDGITWTLDQSSEVLGSGKTLTIQVKEFGD 84
WY DA G++++ T EE+G+ L V G +LT+Q E D
Sbjct: 737 WYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSD 796
Query: 85 AGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPK 124
+G Y CH +LS + E+ T++ Q + +
Sbjct: 797 SGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSR 836
>gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo
sapiens]
Length = 1194
Score = 33.9 bits (76), Expect = 0.20
Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 12/100 (12%)
Query: 37 WY----PDAPGEMVVLTCDTP--------EEDGITWTLDQSSEVLGSGKTLTIQVKEFGD 84
WY DA G++++ T EE+G+ L V G +LT+Q E D
Sbjct: 717 WYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSD 776
Query: 85 AGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPK 124
+G Y CH +LS + E+ T++ Q + +
Sbjct: 777 SGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSR 816
>gi|224591419 zinc finger and BTB domain containing 8B [Homo
sapiens]
Length = 495
Score = 33.5 bits (75), Expect = 0.27
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 16/100 (16%)
Query: 156 VKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVMV-DA 214
V S SS +G +CG +L + G E SVEC +S C + P+E++V D+
Sbjct: 156 VDSESPSSGREGTSCGTKSLVSSPAEG-----EKSVECLRESPCGDCGDCHPLELVVRDS 210
Query: 215 VHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEV 254
+ ++ S+ PPK ++ K ++ +VEV
Sbjct: 211 LGGGSADSNLST----------PPKRIEPKVEFDADEVEV 240
>gi|126116592 Fc fragment of IgG, low affinity IIc, receptor [Homo
sapiens]
Length = 323
Score = 33.5 bits (75), Expect = 0.27
Identities = 33/130 (25%), Positives = 53/130 (40%), Gaps = 6/130 (4%)
Query: 7 VISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTC---DTPEEDGITWTLD 63
++ W +++FLA K V +E W + V LTC +PE D I W +
Sbjct: 28 MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIPWFHN 87
Query: 64 QSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEP 123
+ + + + D+G+YTC G LS + L E + T L+ Q+
Sbjct: 88 GNLIPTHTQPSYRFKANN-NDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQE-- 144
Query: 124 KNKTFLRCEA 133
LRC +
Sbjct: 145 GETIVLRCHS 154
>gi|132814489 low affinity immunoglobulin gamma Fc region receptor
III-B precursor [Homo sapiens]
Length = 233
Score = 33.5 bits (75), Expect = 0.27
Identities = 23/95 (24%), Positives = 38/95 (40%), Gaps = 4/95 (4%)
Query: 12 SLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCD---TPEEDGITWTLDQSSEV 68
+L+ L S + +L K V +E WY + V L C +PE++ W + +
Sbjct: 9 ALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQGAYSPEDNSTQW-FHNENLI 67
Query: 69 LGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLL 103
+ I D+G+Y C LS + L
Sbjct: 68 SSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQL 102
>gi|50511926 Fc fragment of IgG, low affinity IIb, receptor isoform
3 [Homo sapiens]
Length = 291
Score = 33.5 bits (75), Expect = 0.27
Identities = 33/130 (25%), Positives = 53/130 (40%), Gaps = 6/130 (4%)
Query: 7 VISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTC---DTPEEDGITWTLD 63
++ W +++FLA K V +E W + V LTC +PE D I W +
Sbjct: 28 MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 87
Query: 64 QSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEP 123
+ + + + D+G+YTC G LS + L E + T L+ Q+
Sbjct: 88 GNLIPTHTQPSYRFKANN-NDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQE-- 144
Query: 124 KNKTFLRCEA 133
LRC +
Sbjct: 145 GETIVLRCHS 154
>gi|50511930 Fc fragment of IgG, low affinity IIb, receptor isoform
1 [Homo sapiens]
Length = 310
Score = 33.5 bits (75), Expect = 0.27
Identities = 33/130 (25%), Positives = 53/130 (40%), Gaps = 6/130 (4%)
Query: 7 VISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTC---DTPEEDGITWTLD 63
++ W +++FLA K V +E W + V LTC +PE D I W +
Sbjct: 28 MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 87
Query: 64 QSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEP 123
+ + + + D+G+YTC G LS + L E + T L+ Q+
Sbjct: 88 GNLIPTHTQPSYRFKANN-NDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQE-- 144
Query: 124 KNKTFLRCEA 133
LRC +
Sbjct: 145 GETIVLRCHS 154
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 33.5 bits (75), Expect = 0.27
Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 15/112 (13%)
Query: 58 ITWTLDQSS--------EVLGSGKTLTIQVKEFGDAGQYTC---HKGGEVLSHSLLLLHK 106
ITW D ++ SG+ L I DAG+YTC + GE H L +H+
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE 1917
Query: 107 KEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWW----LTTISTDLTF 154
+ +L + N L C+A W+ L + ST +TF
Sbjct: 1918 PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTF 1969
Score = 32.0 bits (71), Expect = 0.77
Identities = 33/158 (20%), Positives = 69/158 (43%), Gaps = 25/158 (15%)
Query: 55 EDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC---HKGGEVLSHSLLLLH----KK 107
+DG +++ +L G+TL I + +AG+Y+C ++ GE++ H + ++
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIN 2670
Query: 108 EDGIWSTDIL-KDQKEPKNKTF-LRCEAKNYSGRFTCWW-----------LTTISTDLTF 154
+ +W + K+ K N T L CEA W+ + + T
Sbjct: 2671 KGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTL 2730
Query: 155 SVKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVE 192
+K ++ SD TC A+ ++ E D +++ +++
Sbjct: 2731 QIKEAQ-ISDTGRYTCVASNIAGE----DELDFDVNIQ 2763
Score = 30.8 bits (68), Expect = 1.7
Identities = 14/36 (38%), Positives = 19/36 (52%)
Query: 55 EDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
+DG +L S +L G+ L + DAGQYTC
Sbjct: 2422 KDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTC 2457
Score = 28.9 bits (63), Expect = 6.6
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 9/67 (13%)
Query: 45 MVVLTCDTPE------EDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC---HKGGE 95
M +T TP DG LD V G L + E D+G+YTC ++ GE
Sbjct: 3455 MACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514
Query: 96 VLSHSLL 102
V H +L
Sbjct: 3515 VSKHFIL 3521
>gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]
Length = 708
Score = 32.7 bits (73), Expect = 0.45
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 58 ITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTC 90
+TWT ++VLGSG TL + DAG Y C
Sbjct: 343 VTWTRRGGAQVLGSGATLRLPSVGPEDAGDYVC 375
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,680,721
Number of Sequences: 37866
Number of extensions: 598382
Number of successful extensions: 1873
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 1680
Number of HSP's gapped (non-prelim): 254
length of query: 328
length of database: 18,247,518
effective HSP length: 103
effective length of query: 225
effective length of database: 14,347,320
effective search space: 3228147000
effective search space used: 3228147000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.