Search of human proteins with 244790016

Search of human proteins with 244790016

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
         (336 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]             686   0.0  
gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]            686   0.0  
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]             667   0.0  
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]            667   0.0  
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]            667   0.0  
gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]             667   0.0  
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]             667   0.0  
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]             667   0.0  
gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]             664   0.0  
gi|14249614 synaptotagmin-like 1 [Homo sapiens]                       322   2e-88
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      284   9e-77
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      284   9e-77
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]            251   5e-67
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]            251   6e-67
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]             251   6e-67
gi|110227631 synaptotagmin-like 3 [Homo sapiens]                      194   1e-49
gi|238550198 synaptotagmin III [Homo sapiens]                         112   6e-25
gi|238550196 synaptotagmin III [Homo sapiens]                         112   6e-25
gi|14150054 synaptotagmin III [Homo sapiens]                          112   6e-25
gi|45504376 synaptotagmin VI [Homo sapiens]                           111   8e-25
gi|211059429 synaptotagmin II [Homo sapiens]                          110   2e-24
gi|31543670 synaptotagmin II [Homo sapiens]                           110   2e-24
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            107   1e-23
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             107   1e-23
gi|39752671 synaptotagmin X [Homo sapiens]                            107   2e-23
gi|6005997 double C2-like domains, beta [Homo sapiens]                107   2e-23
gi|209447073 synaptotagmin I [Homo sapiens]                           102   6e-22
gi|5032139 synaptotagmin I [Homo sapiens]                             102   6e-22
gi|209447070 synaptotagmin I [Homo sapiens]                           102   6e-22
gi|28376627 synaptotagmin IX [Homo sapiens]                           100   1e-21

>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score =  686 bits (1771), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 60
           MSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA
Sbjct: 575 MSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 634

Query: 61  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 120
           DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI
Sbjct: 635 DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 694

Query: 121 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQY 180
           WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQY
Sbjct: 695 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQY 754

Query: 181 VPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKT 240
           VPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKT
Sbjct: 755 VPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKT 814

Query: 241 TNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMD 300
           TNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMD
Sbjct: 815 TNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMD 874

Query: 301 STSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 336
           STSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
Sbjct: 875 STSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 910


>gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
          Length = 336

 Score =  686 bits (1771), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 60
           MSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA
Sbjct: 1   MSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 60

Query: 61  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 120
           DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI
Sbjct: 61  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 120

Query: 121 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQY 180
           WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQY
Sbjct: 121 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQY 180

Query: 181 VPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKT 240
           VPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKT
Sbjct: 181 VPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKT 240

Query: 241 TNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMD 300
           TNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMD
Sbjct: 241 TNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMD 300

Query: 301 STSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 336
           STSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
Sbjct: 301 STSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 336


>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
          Length = 376

 Score =  667 bits (1720), Expect = 0.0
 Identities = 336/376 (89%), Positives = 336/376 (89%), Gaps = 40/376 (10%)

Query: 1   MSKSVPAFLQDE----------------------------------------VSGSVMSV 20
           MSKSVPAFLQDE                                        VSGSVMSV
Sbjct: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60

Query: 21  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 80
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120

Query: 81  KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 140
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180

Query: 141 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 200
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240

Query: 201 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 260
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300

Query: 261 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 320
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360

Query: 321 EATLPLRMLLIAKISK 336
           EATLPLRMLLIAKISK
Sbjct: 361 EATLPLRMLLIAKISK 376


>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
          Length = 935

 Score =  667 bits (1720), Expect = 0.0
 Identities = 336/376 (89%), Positives = 336/376 (89%), Gaps = 40/376 (10%)

Query: 1   MSKSVPAFLQDE----------------------------------------VSGSVMSV 20
           MSKSVPAFLQDE                                        VSGSVMSV
Sbjct: 560 MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 619

Query: 21  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 80
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 620 YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 679

Query: 81  KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 140
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 680 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 739

Query: 141 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 200
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 740 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 799

Query: 201 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 260
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 800 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 859

Query: 261 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 320
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 860 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 919

Query: 321 EATLPLRMLLIAKISK 336
           EATLPLRMLLIAKISK
Sbjct: 920 EATLPLRMLLIAKISK 935


>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
          Length = 934

 Score =  667 bits (1720), Expect = 0.0
 Identities = 336/376 (89%), Positives = 336/376 (89%), Gaps = 40/376 (10%)

Query: 1   MSKSVPAFLQDE----------------------------------------VSGSVMSV 20
           MSKSVPAFLQDE                                        VSGSVMSV
Sbjct: 559 MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 618

Query: 21  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 80
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 619 YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 678

Query: 81  KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 140
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 679 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 738

Query: 141 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 200
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 739 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 798

Query: 201 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 260
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 799 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 858

Query: 261 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 320
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 859 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 918

Query: 321 EATLPLRMLLIAKISK 336
           EATLPLRMLLIAKISK
Sbjct: 919 EATLPLRMLLIAKISK 934


>gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
          Length = 376

 Score =  667 bits (1720), Expect = 0.0
 Identities = 336/376 (89%), Positives = 336/376 (89%), Gaps = 40/376 (10%)

Query: 1   MSKSVPAFLQDE----------------------------------------VSGSVMSV 20
           MSKSVPAFLQDE                                        VSGSVMSV
Sbjct: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60

Query: 21  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 80
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120

Query: 81  KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 140
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180

Query: 141 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 200
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240

Query: 201 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 260
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300

Query: 261 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 320
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360

Query: 321 EATLPLRMLLIAKISK 336
           EATLPLRMLLIAKISK
Sbjct: 361 EATLPLRMLLIAKISK 376


>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
          Length = 1256

 Score =  667 bits (1720), Expect = 0.0
 Identities = 336/376 (89%), Positives = 336/376 (89%), Gaps = 40/376 (10%)

Query: 1    MSKSVPAFLQDE----------------------------------------VSGSVMSV 20
            MSKSVPAFLQDE                                        VSGSVMSV
Sbjct: 881  MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 940

Query: 21   YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 80
            YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 941  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 1000

Query: 81   KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 140
            KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 1001 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 1060

Query: 141  TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 200
            TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 1061 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 1120

Query: 201  KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 260
            KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 1121 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 1180

Query: 261  EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 320
            EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 1181 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 1240

Query: 321  EATLPLRMLLIAKISK 336
            EATLPLRMLLIAKISK
Sbjct: 1241 EATLPLRMLLIAKISK 1256


>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
          Length = 1272

 Score =  667 bits (1720), Expect = 0.0
 Identities = 336/376 (89%), Positives = 336/376 (89%), Gaps = 40/376 (10%)

Query: 1    MSKSVPAFLQDE----------------------------------------VSGSVMSV 20
            MSKSVPAFLQDE                                        VSGSVMSV
Sbjct: 897  MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 956

Query: 21   YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 80
            YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 957  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 1016

Query: 81   KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 140
            KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 1017 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 1076

Query: 141  TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 200
            TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 1077 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 1136

Query: 201  KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 260
            KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 1137 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 1196

Query: 261  EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 320
            EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 1197 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 1256

Query: 321  EATLPLRMLLIAKISK 336
            EATLPLRMLLIAKISK
Sbjct: 1257 EATLPLRMLLIAKISK 1272


>gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
          Length = 365

 Score =  664 bits (1712), Expect = 0.0
 Identities = 324/324 (100%), Positives = 324/324 (100%)

Query: 13  VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 72
           VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK
Sbjct: 42  VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 101

Query: 73  AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 132
           AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL
Sbjct: 102 AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 161

Query: 133 GEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPT 192
           GEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPT
Sbjct: 162 GEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPT 221

Query: 193 TGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYD 252
           TGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYD
Sbjct: 222 TGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYD 281

Query: 253 GFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKM 312
           GFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKM
Sbjct: 282 GFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKM 341

Query: 313 VNSPNTWIEATLPLRMLLIAKISK 336
           VNSPNTWIEATLPLRMLLIAKISK
Sbjct: 342 VNSPNTWIEATLPLRMLLIAKISK 365


>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
          Length = 550

 Score =  322 bits (826), Expect = 2e-88
 Identities = 160/326 (49%), Positives = 220/326 (67%), Gaps = 9/326 (2%)

Query: 2   SKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAAD 61
           S SV +     +SGS MS+ SGD   ++V+G++ FA+ Y     EL V V QC+ LAAA 
Sbjct: 227 SSSVSSLNSSTLSGSQMSL-SGDAEAVQVRGSVHFALHYEPGAAELRVHVIQCQGLAAA- 284

Query: 62  VKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIW 121
            +++RSDPYVK+YLLPDK    K+KT V K+ LNPV+NE LRY + +  L+ + L+LS+W
Sbjct: 285 -RRRRSDPYVKSYLLPDK--QSKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVW 341

Query: 122 HRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYV 181
           HR++  RN FLGEVE+ L+TWDW ++      W PL+ +  P   +  +RG + L+L+YV
Sbjct: 342 HRESLGRNIFLGEVEVPLDTWDWGSEPT----WLPLQPRVPPSPDDLPSRGLLALSLKYV 397

Query: 182 PEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTT 241
           P    G  LP +GE+H WVKE  DL  LR   L+++V+C +LPD S+ SRQ+TR V ++ 
Sbjct: 398 PAGSEGAGLPPSGELHFWVKEARDLLPLRAGSLDTYVQCFVLPDDSQASRQRTRVVRRSL 457

Query: 242 NPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDS 301
           +P+FNHTMVYDGF P DL +AC EL++WDH  L N+ LGG R+  GTG SYG +V WMDS
Sbjct: 458 SPVFNHTMVYDGFGPADLRQACAELSLWDHGALANRQLGGTRLSLGTGSSYGLQVPWMDS 517

Query: 302 TSEEVALWEKMVNSPNTWIEATLPLR 327
           T EE  LW+ ++  P  W++  LPLR
Sbjct: 518 TPEEKQLWQALLEQPCEWVDGLLPLR 543


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  284 bits (726), Expect = 9e-77
 Identities = 148/324 (45%), Positives = 210/324 (64%), Gaps = 12/324 (3%)

Query: 15  GSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 72
           GS+MS+YS  GDFGN+ V G I F+++Y +  + L V V +C  LA AD  K+RS+PYVK
Sbjct: 339 GSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVK 398

Query: 73  AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 132
            YLLPDK + GK+KT + + T+NP+Y+E LRY+I + +L  + L  S+WH   F RN+FL
Sbjct: 399 TYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFL 458

Query: 133 GEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKK 189
           GE E+ +++W  D K +  L  +      +P  L + ++GE+ ++L+Y+P    PV G +
Sbjct: 459 GEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDR 517

Query: 190 LPTT----GEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPI 244
             +     GE+ +W+KE  +L   + G   +SFVK  +LP  ++ S++KT  + KT NP 
Sbjct: 518 KKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPH 577

Query: 245 FNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTS 303
           +NHT VY+G R EDL   C+ELTVWD   L +N FLGG+R+G GTG S G  VDWMDST 
Sbjct: 578 YNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTG 637

Query: 304 EEVALWEKMVNSPNTWIEATLPLR 327
           EEV+LW+KM   P +W E TL LR
Sbjct: 638 EEVSLWQKMRQYPGSWAEGTLQLR 661


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  284 bits (726), Expect = 9e-77
 Identities = 148/324 (45%), Positives = 210/324 (64%), Gaps = 12/324 (3%)

Query: 15  GSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 72
           GS+MS+YS  GDFGN+ V G I F+++Y +  + L V V +C  LA AD  K+RS+PYVK
Sbjct: 339 GSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVK 398

Query: 73  AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 132
            YLLPDK + GK+KT + + T+NP+Y+E LRY+I + +L  + L  S+WH   F RN+FL
Sbjct: 399 TYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFL 458

Query: 133 GEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKK 189
           GE E+ +++W  D K +  L  +      +P  L + ++GE+ ++L+Y+P    PV G +
Sbjct: 459 GEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDR 517

Query: 190 LPTT----GEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPI 244
             +     GE+ +W+KE  +L   + G   +SFVK  +LP  ++ S++KT  + KT NP 
Sbjct: 518 KKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPH 577

Query: 245 FNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTS 303
           +NHT VY+G R EDL   C+ELTVWD   L +N FLGG+R+G GTG S G  VDWMDST 
Sbjct: 578 YNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTG 637

Query: 304 EEVALWEKMVNSPNTWIEATLPLR 327
           EEV+LW+KM   P +W E TL LR
Sbjct: 638 EEVSLWQKMRQYPGSWAEGTLQLR 661


>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score =  251 bits (642), Expect = 5e-67
 Identities = 143/351 (40%), Positives = 210/351 (59%), Gaps = 32/351 (9%)

Query: 4   SVPAFLQDEVS-GSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 60
           +VP    D  S  S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  
Sbjct: 399 NVPDADSDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIG 458

Query: 61  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 120
           D KKQR+D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+
Sbjct: 459 DEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSV 517

Query: 121 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLAL 178
           WH D F RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L
Sbjct: 518 WHYDRFGRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVL 573

Query: 179 QYV---------PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSF 217
           +Y+         PE + G K           + + G + +++KE  +L  ++ G   +SF
Sbjct: 574 RYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSF 633

Query: 218 VKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TN 276
           VK  +LPD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N
Sbjct: 634 VKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN 693

Query: 277 QFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 327
            FLGG+R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 694 IFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744


>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  251 bits (641), Expect = 6e-67
 Identities = 139/338 (41%), Positives = 205/338 (60%), Gaps = 31/338 (9%)

Query: 16  SVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKA 73
           S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+
Sbjct: 390 SMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKS 449

Query: 74  YLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLG 133
           YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLG
Sbjct: 450 YLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLG 508

Query: 134 EVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------P 182
           EVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         P
Sbjct: 509 EVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPP 564

Query: 183 EPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKS 230
           E + G K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ +
Sbjct: 565 EQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKAT 624

Query: 231 RQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTG 289
           + KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G
Sbjct: 625 KHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSG 684

Query: 290 KSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 327
            S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 685 VSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722


>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  251 bits (641), Expect = 6e-67
 Identities = 139/338 (41%), Positives = 205/338 (60%), Gaps = 31/338 (9%)

Query: 16  SVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKA 73
           S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+
Sbjct: 390 SMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKS 449

Query: 74  YLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLG 133
           YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLG
Sbjct: 450 YLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLG 508

Query: 134 EVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------P 182
           EVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         P
Sbjct: 509 EVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPP 564

Query: 183 EPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKS 230
           E + G K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ +
Sbjct: 565 EQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKAT 624

Query: 231 RQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTG 289
           + KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G
Sbjct: 625 KHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSG 684

Query: 290 KSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 327
            S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 685 VSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722


>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
          Length = 542

 Score =  194 bits (492), Expect = 1e-49
 Identities = 119/330 (36%), Positives = 180/330 (54%), Gaps = 24/330 (7%)

Query: 15  GSVMSVYS-----GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDP 69
           GS++S+ S     G+F N  V G I+FAI Y      L + +  CK+LA  + KK++ +P
Sbjct: 218 GSLISIDSTCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNP 277

Query: 70  YVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRN 129
           YVK YLLPD+   GK+KT V + T++P + E L+Y++    L T++L +S+WH  T  R 
Sbjct: 278 YVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARR 337

Query: 130 SFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA-ENRGEM----KLALQYVP-- 182
            FLGEV + L TWD+++   +  RW+PL+ K         ++ GE+    KL L   P  
Sbjct: 338 VFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRK 397

Query: 183 --EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFVK-CTILPDTSRKSRQKTRAVG 238
             E   G   P+  G++ + V    +LP+     LNSFVK C  LPD  +K R K+  + 
Sbjct: 398 LQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGCLTLPD-QQKLRLKSPVLR 456

Query: 239 KTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLTNQFLGGLRIGFGTGKSYGTEV 296
           K   P + H+ V+ G  P  L ++ +ELTVWD   + + ++ LGG R+G     S G   
Sbjct: 457 KQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLG-----SKGDTA 511

Query: 297 DWMDSTSEEVALWEKMVNSPNTWIEATLPL 326
              D+ S     W+K+++SPN W + TL L
Sbjct: 512 VGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 6e-25
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 22  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 81
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 82  MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 139
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 140 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 199
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 200 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 258
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 259 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 313
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 6e-25
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 22  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 81
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 82  MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 139
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 140 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 199
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 200 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 258
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 259 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 313
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 6e-25
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 22  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 81
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 82  MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 139
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 140 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 199
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 200 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 258
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 259 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 313
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  111 bits (278), Expect = 8e-25
 Identities = 84/295 (28%), Positives = 152/295 (51%), Gaps = 25/295 (8%)

Query: 32  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 91
           G I F++ Y    + L V + +  DL A D     SDPYVK YLLPD+    K +T V +
Sbjct: 146 GKINFSLRYDYETETLIVRILKAFDLPAKDFCGS-SDPYVKIYLLPDR--KCKLQTRVHR 202

Query: 92  KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 151
           KTLNP ++E   + +  + L  +KL+LS++  D F R+  +GEV LD   ++  +   + 
Sbjct: 203 KTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRET 261

Query: 152 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 210
             W  ++  T+    E+ + GE+  +L Y         LPT G + + V +C +L  +  
Sbjct: 262 SIWKDIQYATS----ESVDLGEIMFSLCY---------LPTAGRLTLTVIKCRNLKAMDI 308

Query: 211 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 270
             + + +VK ++L D  R  ++KT     T NP++N  +++D   PE++ +  + ++V D
Sbjct: 309 TGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFD-IPPENMDQVSLLISVMD 367

Query: 271 HYKL-TNQFLGGLRIGF---GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIE 321
           + ++  N+ +G  R+G    G G+ +  E+  +    + +A W  +V    ++ E
Sbjct: 368 YDRVGHNEIIGVCRVGITAEGLGRDHWNEM--LAYPRKPIAHWHSLVEVKKSFKE 420


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  110 bits (275), Expect = 2e-24
 Identities = 89/299 (29%), Positives = 150/299 (50%), Gaps = 30/299 (10%)

Query: 32  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 91
           G +QF+++Y     +L V V Q  +L A D+    SDPYVK +LLPDK K  K +T V +
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197

Query: 92  KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 151
           KTLNP +NE   +K+  Q L  + L ++I+  D F ++  +GEV++ + T D      + 
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256

Query: 152 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 210
             W  L+        E E  G++  +L+YV         PT G++ + + E  +L  +  
Sbjct: 257 --WRDLQGGEKE---EPEKLGDICTSLRYV---------PTAGKLTVCILEAKNLKKMDV 302

Query: 211 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 270
           G   + +VK  ++ +  R  ++KT    KT NP FN +  ++    E + +  V +TV D
Sbjct: 303 GGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLD 361

Query: 271 HYKL-TNQFLGGLRIGFGTGKSYGTEV----DWMDSTSEEVALWEKMVNSPNTWIEATL 324
           + KL  N+ +G + +G     + GTE+    D + +    +A W  +   P   ++A L
Sbjct: 362 YDKLGKNEAIGKIFVG---SNATGTELRHWSDMLANPRRPIAQWHSL--KPEEEVDALL 415



 Score = 65.1 bits (157), Expect = 9e-11
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 29  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 88
           E  G+I  ++ YV +  +L V + + K+L   DV    SDPYVK +L+ +  ++ KKKT 
Sbjct: 269 EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL-SDPYVKIHLMQNGKRLKKKKTT 327

Query: 89  VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVEL-------DLET 141
           V KKTLNP +NE   ++I  + ++  ++ +++   D   +N  +G++ +       +L  
Sbjct: 328 VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRH 387

Query: 142 WD--WDNKQNKQLRWYPLKRKTAPVALEAENR 171
           W     N +    +W+ LK +    AL  +N+
Sbjct: 388 WSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  110 bits (275), Expect = 2e-24
 Identities = 89/299 (29%), Positives = 150/299 (50%), Gaps = 30/299 (10%)

Query: 32  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 91
           G +QF+++Y     +L V V Q  +L A D+    SDPYVK +LLPDK K  K +T V +
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197

Query: 92  KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 151
           KTLNP +NE   +K+  Q L  + L ++I+  D F ++  +GEV++ + T D      + 
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256

Query: 152 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 210
             W  L+        E E  G++  +L+YV         PT G++ + + E  +L  +  
Sbjct: 257 --WRDLQGGEKE---EPEKLGDICTSLRYV---------PTAGKLTVCILEAKNLKKMDV 302

Query: 211 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 270
           G   + +VK  ++ +  R  ++KT    KT NP FN +  ++    E + +  V +TV D
Sbjct: 303 GGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLD 361

Query: 271 HYKL-TNQFLGGLRIGFGTGKSYGTEV----DWMDSTSEEVALWEKMVNSPNTWIEATL 324
           + KL  N+ +G + +G     + GTE+    D + +    +A W  +   P   ++A L
Sbjct: 362 YDKLGKNEAIGKIFVG---SNATGTELRHWSDMLANPRRPIAQWHSL--KPEEEVDALL 415



 Score = 65.1 bits (157), Expect = 9e-11
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 29  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 88
           E  G+I  ++ YV +  +L V + + K+L   DV    SDPYVK +L+ +  ++ KKKT 
Sbjct: 269 EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL-SDPYVKIHLMQNGKRLKKKKTT 327

Query: 89  VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVEL-------DLET 141
           V KKTLNP +NE   ++I  + ++  ++ +++   D   +N  +G++ +       +L  
Sbjct: 328 VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRH 387

Query: 142 WD--WDNKQNKQLRWYPLKRKTAPVALEAENR 171
           W     N +    +W+ LK +    AL  +N+
Sbjct: 388 WSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  107 bits (268), Expect = 1e-23
 Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 33/305 (10%)

Query: 32  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 91
           G ++F++ Y +    L   + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 394 GALEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLR 452

Query: 92  KTLNPVYNEILRYK-IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 150
            T NP++NE L Y  I  + ++ + L +S+   D F  N F+GE    L+    + ++N 
Sbjct: 453 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 512

Query: 151 QL---RWYPLKR-----KTAPVAL----------EAENRGEMKLALQYVPEPVPGKKLPT 192
            +   R  P+KR         +AL          + E RG++ ++L Y  +         
Sbjct: 513 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQ--------- 563

Query: 193 TGEVHIWVKECLDLPLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 251
            G + + +  C+ L  +    + + FVK  + PD  +K++ KT+   KT NP FN    Y
Sbjct: 564 QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFY 623

Query: 252 DGFRPEDLMEACVELTVWDH-YKLTNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALW 309
           D  +  DL +  ++++VWD+    +N ++GG ++G    G+      + + +  +++  W
Sbjct: 624 D-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 682

Query: 310 EKMVN 314
            ++ N
Sbjct: 683 HQLQN 687



 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)

Query: 26  GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 85
           G++E +G I  ++ Y      L V + +C  LAA D     SDP+VK +L PD GK  K 
Sbjct: 546 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 604

Query: 86  KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 138
           KT + KKTLNP +NE   Y I+   L  + L++S+W  D  K N ++G  +L        
Sbjct: 605 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 664

Query: 139 LETW--DWDNKQNKQLRWYPLKRK 160
           L+ W     NK  K  RW+ L+ +
Sbjct: 665 LKHWYECLKNKDKKIERWHQLQNE 688


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  107 bits (268), Expect = 1e-23
 Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 33/305 (10%)

Query: 32  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 91
           G ++F++ Y +    L   + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 390 GALEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLR 448

Query: 92  KTLNPVYNEILRYK-IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 150
            T NP++NE L Y  I  + ++ + L +S+   D F  N F+GE    L+    + ++N 
Sbjct: 449 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 508

Query: 151 QL---RWYPLKR-----KTAPVAL----------EAENRGEMKLALQYVPEPVPGKKLPT 192
            +   R  P+KR         +AL          + E RG++ ++L Y  +         
Sbjct: 509 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQ--------- 559

Query: 193 TGEVHIWVKECLDLPLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 251
            G + + +  C+ L  +    + + FVK  + PD  +K++ KT+   KT NP FN    Y
Sbjct: 560 QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFY 619

Query: 252 DGFRPEDLMEACVELTVWDH-YKLTNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALW 309
           D  +  DL +  ++++VWD+    +N ++GG ++G    G+      + + +  +++  W
Sbjct: 620 D-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 678

Query: 310 EKMVN 314
            ++ N
Sbjct: 679 HQLQN 683



 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)

Query: 26  GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 85
           G++E +G I  ++ Y      L V + +C  LAA D     SDP+VK +L PD GK  K 
Sbjct: 542 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 600

Query: 86  KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 138
           KT + KKTLNP +NE   Y I+   L  + L++S+W  D  K N ++G  +L        
Sbjct: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660

Query: 139 LETW--DWDNKQNKQLRWYPLKRK 160
           L+ W     NK  K  RW+ L+ +
Sbjct: 661 LKHWYECLKNKDKKIERWHQLQNE 684


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  107 bits (266), Expect = 2e-23
 Identities = 79/276 (28%), Positives = 144/276 (52%), Gaps = 25/276 (9%)

Query: 27  NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK 86
           ++++ G + F ++Y    + L V + +  DL A D     SDPYVK YLLPD+ K  K +
Sbjct: 228 DVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGT-SDPYVKMYLLPDRKK--KFQ 284

Query: 87  TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDN 146
           T V +KTLNP+++E  ++ +    L  +KL+ S++  D F R+  +GEV LD   ++  +
Sbjct: 285 TRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILD-NLFEVSD 343

Query: 147 KQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL 206
              +   W  +   T     E+ + GE+  +L Y         LPT G + + V +C +L
Sbjct: 344 LSREATVWKDIHCATT----ESIDLGEIMFSLCY---------LPTAGRMTLTVIKCRNL 390

Query: 207 PL--LRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 264
               + GS  + +VK +++ +  R  ++KT     T NP++N  +++D   PE++ +  +
Sbjct: 391 KAMDITGSS-DPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFD-IPPENVDQVSL 448

Query: 265 ELTVWDHYKL-TNQFLGGLRIGF---GTGKSYGTEV 296
            + V D+ ++  N+ +G  R G    G G+ +  E+
Sbjct: 449 SIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEM 484


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  107 bits (266), Expect = 2e-23
 Identities = 79/291 (27%), Positives = 133/291 (45%), Gaps = 23/291 (7%)

Query: 32  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 91
           G + F++ Y +    LH  + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 128 GTLDFSLLYDQENNALHCTITKAKGLKPMD-HNGLADPYVKLHLLPGASKANKLRTKTLR 186

Query: 92  KTLNPVYNEILR-YKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 150
            TLNP +NE L  Y I  + +  + L +S+   D F+ N F+GE  + L+      K N 
Sbjct: 187 NTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKL----KPNH 242

Query: 151 QLRWYPLKRKTAPV----ALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL 206
              +     K  PV        E RG + ++L+Y  +            + + +  C  L
Sbjct: 243 TKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQ---------KQGLLVGIVRCAHL 293

Query: 207 PLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVE 265
             +    + + +VK  + PD  +KS+ KT    KT NP FN    Y+  +  DL +  +E
Sbjct: 294 AAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYE-IKHGDLAKKSLE 352

Query: 266 LTVWDH-YKLTNQFLGGLRIGF-GTGKSYGTEVDWMDSTSEEVALWEKMVN 314
           +TVWD+    +N F+GG+ +G    G+      D + +  + +  W  + +
Sbjct: 353 VTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTS 403



 Score = 85.1 bits (209), Expect = 8e-17
 Identities = 54/140 (38%), Positives = 73/140 (52%), Gaps = 10/140 (7%)

Query: 27  NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK 86
           +LE +G I  +++Y    + L V + +C  LAA D     SDPYVK YL PD  K  K K
Sbjct: 263 SLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGY-SDPYVKTYLRPDVDKKSKHK 321

Query: 87  TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD-------L 139
           T V KKTLNP +NE   Y+I+   L  + L +++W  D  K N F+G V L        L
Sbjct: 322 TAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERL 381

Query: 140 ETW--DWDNKQNKQLRWYPL 157
           + W     NK  +  RW+ L
Sbjct: 382 KHWFDCLKNKDKRIERWHTL 401


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 6e-22
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 29  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 88
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 89  VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 148
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 149 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 208
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 209 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 267
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 268 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 316
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 6e-22
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 29  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 88
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 89  VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 148
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 149 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 208
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 209 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 267
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 268 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 316
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 6e-22
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 29  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 88
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 89  VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 148
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 149 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 208
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 209 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 267
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 268 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 316
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  100 bits (250), Expect = 1e-21
 Identities = 79/296 (26%), Positives = 151/296 (51%), Gaps = 25/296 (8%)

Query: 23  GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKM 82
           G   N +  G + F ++Y   L++L V + +  +L A D     SDPYVK YLLPD+   
Sbjct: 213 GRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGT-SDPYVKIYLLPDRKT- 270

Query: 83  GKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETW 142
            K +T V +KTLNPV++E+  + +    L+ +KL+ S++  D F R+  +G+V +D    
Sbjct: 271 -KHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD-HFL 328

Query: 143 DWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKE 202
           D  +   + + W  ++     V  +  + GE+  +L Y         LPT G + I + +
Sbjct: 329 DLADFPRECILWKDIEY----VTNDNVDLGELMFSLCY---------LPTAGRLTITIIK 375

Query: 203 CLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLME 261
             +L  +  +  +  +VK +++ D  R  ++KT     T NP++N  +V+D   PE++ +
Sbjct: 376 ARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFD-VPPENIDQ 434

Query: 262 ACVELTVWDHYKL-TNQFLGGLRIGFGT---GKSYGTEVDWMDSTSEEVALWEKMV 313
             + + V D+ ++  N+ +G  ++G      G+ + +E+  +    + +A W  +V
Sbjct: 435 IHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEM--LSYPRKPIAHWHSLV 488


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,690,951
Number of Sequences: 37866
Number of extensions: 572861
Number of successful extensions: 1716
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 1285
Number of HSP's gapped (non-prelim): 305
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.