Search of human proteins with 244790013

Search of human proteins with 244790013

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
         (934 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]           1858   0.0  
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]           1854   0.0  
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]            1754   0.0  
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]             900   0.0  
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]             889   0.0  
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]             760   0.0  
gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]             760   0.0  
gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]             738   0.0  
gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]            667   0.0  
gi|14249614 synaptotagmin-like 1 [Homo sapiens]                       330   3e-90
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      298   2e-80
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      298   2e-80
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]            271   3e-72
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]             271   3e-72
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]            270   6e-72
gi|110227631 synaptotagmin-like 3 [Homo sapiens]                      195   1e-49
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            114   3e-25
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             114   3e-25
gi|45504376 synaptotagmin VI [Homo sapiens]                           112   2e-24
gi|238550198 synaptotagmin III [Homo sapiens]                         112   2e-24
gi|238550196 synaptotagmin III [Homo sapiens]                         112   2e-24
gi|14150054 synaptotagmin III [Homo sapiens]                          112   2e-24
gi|211059429 synaptotagmin II [Homo sapiens]                          110   6e-24
gi|31543670 synaptotagmin II [Homo sapiens]                           110   6e-24
gi|39752671 synaptotagmin X [Homo sapiens]                            107   7e-23
gi|6005997 double C2-like domains, beta [Homo sapiens]                107   7e-23
gi|28376627 synaptotagmin IX [Homo sapiens]                           102   1e-21
gi|209447073 synaptotagmin I [Homo sapiens]                           102   2e-21
gi|5032139 synaptotagmin I [Homo sapiens]                             102   2e-21
gi|209447070 synaptotagmin I [Homo sapiens]                           102   2e-21

>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
          Length = 934

 Score = 1858 bits (4814), Expect = 0.0
 Identities = 934/934 (100%), Positives = 934/934 (100%)

Query: 1   MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60
           MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
Sbjct: 1   MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60

Query: 61  RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP 120
           RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
Sbjct: 61  RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP 120

Query: 121 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ 180
           EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
Sbjct: 121 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ 180

Query: 181 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM 240
           SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
Sbjct: 181 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM 240

Query: 241 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV 300
           IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
Sbjct: 241 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV 300

Query: 301 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE 360
           SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
Sbjct: 301 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE 360

Query: 361 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL 420
           SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
Sbjct: 361 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL 420

Query: 421 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS 480
           HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
Sbjct: 421 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS 480

Query: 481 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVS 540
           SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVS
Sbjct: 481 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVS 540

Query: 541 TVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLS 600
           TVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLS
Sbjct: 541 TVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLS 600

Query: 601 SSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADV 660
           SSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADV
Sbjct: 601 SSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADV 660

Query: 661 KKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWH 720
           KKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWH
Sbjct: 661 KKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWH 720

Query: 721 RDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP 780
           RDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP
Sbjct: 721 RDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP 780

Query: 781 EPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTN 840
           EPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTN
Sbjct: 781 EPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTN 840

Query: 841 PIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDST 900
           PIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDST
Sbjct: 841 PIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDST 900

Query: 901 SEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 934
           SEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
Sbjct: 901 SEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 934


>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
          Length = 935

 Score = 1854 bits (4802), Expect = 0.0
 Identities = 934/935 (99%), Positives = 934/935 (99%), Gaps = 1/935 (0%)

Query: 1   MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60
           MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
Sbjct: 1   MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60

Query: 61  RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP 120
           RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
Sbjct: 61  RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP 120

Query: 121 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEK-RKNPFNSSKLPEGHSSQQTKNE 179
           EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEK RKNPFNSSKLPEGHSSQQTKNE
Sbjct: 121 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKQRKNPFNSSKLPEGHSSQQTKNE 180

Query: 180 QSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARK 239
           QSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARK
Sbjct: 181 QSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARK 240

Query: 240 MIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKI 299
           MIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKI
Sbjct: 241 MIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKI 300

Query: 300 VSPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVL 359
           VSPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVL
Sbjct: 301 VSPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVL 360

Query: 360 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPING 419
           ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPING
Sbjct: 361 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPING 420

Query: 420 LHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGG 479
           LHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGG
Sbjct: 421 LHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGG 480

Query: 480 SSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDV 539
           SSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDV
Sbjct: 481 SSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDV 540

Query: 540 STVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNL 599
           STVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNL
Sbjct: 541 STVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNL 600

Query: 600 SSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAAD 659
           SSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAAD
Sbjct: 601 SSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAAD 660

Query: 660 VKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIW 719
           VKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIW
Sbjct: 661 VKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIW 720

Query: 720 HRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYV 779
           HRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYV
Sbjct: 721 HRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYV 780

Query: 780 PEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTT 839
           PEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTT
Sbjct: 781 PEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTT 840

Query: 840 NPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDS 899
           NPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDS
Sbjct: 841 NPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDS 900

Query: 900 TSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 934
           TSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
Sbjct: 901 TSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 935


>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score = 1754 bits (4543), Expect = 0.0
 Identities = 893/950 (94%), Positives = 894/950 (94%), Gaps = 56/950 (5%)

Query: 1   MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60
           MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
Sbjct: 1   MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60

Query: 61  RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP 120
           RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
Sbjct: 61  RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP 120

Query: 121 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ 180
           EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
Sbjct: 121 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ 180

Query: 181 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM 240
           SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
Sbjct: 181 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM 240

Query: 241 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV 300
           IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
Sbjct: 241 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV 300

Query: 301 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE 360
           SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
Sbjct: 301 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE 360

Query: 361 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL 420
           SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
Sbjct: 361 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL 420

Query: 421 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS 480
           HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
Sbjct: 421 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS 480

Query: 481 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAED-- 538
           SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAED  
Sbjct: 481 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDE 540

Query: 539 --------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSY 584
                         +STVPTQPDNPFSHPDKLKRMSKSVPAFLQDE              
Sbjct: 541 KPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE-------------- 586

Query: 585 QLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKE 644
                                     VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKE
Sbjct: 587 --------------------------VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKE 620

Query: 645 LHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKI 704
           LHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKI
Sbjct: 621 LHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKI 680

Query: 705 EKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVAL 764
           EKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVAL
Sbjct: 681 EKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVAL 740

Query: 765 EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDT 824
           EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDT
Sbjct: 741 EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDT 800

Query: 825 SRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGF 884
           SRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGF
Sbjct: 801 SRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGF 860

Query: 885 GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 934
           GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
Sbjct: 861 GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 910


>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
          Length = 1256

 Score =  900 bits (2326), Expect = 0.0
 Identities = 483/649 (74%), Positives = 514/649 (79%), Gaps = 24/649 (3%)

Query: 302  PGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLES 361
            P +++ E   EKE S  + +      P  +   S   +   +S GL       E  V + 
Sbjct: 616  PQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNGL-------ESQVNQC 668

Query: 362  DRLKNG--------MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSK-SETHQPMTS 412
            D++  G        ++  G     +    P  Y    +    T +P   + SE+      
Sbjct: 669  DKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDSESGVAGGQ 728

Query: 413  GSFPINGLHSHSEVLTARPQSMENSPTI----NEPKDKSSELTRLESVLPRSPADELSHC 468
            G+    G    SE ++   ++ +  P +    N  K    ELT     + +   +E    
Sbjct: 729  GTLQEPGFGEASEAISVS-RNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEGF 787

Query: 469  VEPEPSQVPGGSSRD---RQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV 525
             E + S     S+ +       SEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV
Sbjct: 788  SESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV 847

Query: 526  DNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQ 585
            DNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQ
Sbjct: 848  DNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQ 907

Query: 586  LSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKEL 645
            LSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKEL
Sbjct: 908  LSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKEL 967

Query: 646  HVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIE 705
            HVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIE
Sbjct: 968  HVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIE 1027

Query: 706  KQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALE 765
            KQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALE
Sbjct: 1028 KQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALE 1087

Query: 766  AENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTS 825
            AENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTS
Sbjct: 1088 AENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTS 1147

Query: 826  RKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFG 885
            RKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFG
Sbjct: 1148 RKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFG 1207

Query: 886  TGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 934
            TGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
Sbjct: 1208 TGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 1256


>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
          Length = 1272

 Score =  889 bits (2298), Expect = 0.0
 Identities = 482/665 (72%), Positives = 514/665 (77%), Gaps = 40/665 (6%)

Query: 302  PGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLES 361
            P +++ E   EKE S  + +      P  +   S   +   +S GL       E  V + 
Sbjct: 616  PQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNGL-------ESQVNQC 668

Query: 362  DRLKNG--------MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSK-SETHQPMTS 412
            D++  G        ++  G     +    P  Y    +    T +P   + SE+      
Sbjct: 669  DKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDSESGVAGGQ 728

Query: 413  GSFPINGLHSHSEVLTARPQSMENSPTI----NEPKDKSSELTRLESVLPRSPADELSHC 468
            G+    G    SE ++   ++ +  P +    N  K    ELT     + +   +E    
Sbjct: 729  GTLQEPGFGEASEAISVS-RNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEGF 787

Query: 469  VEPEPSQVPGGSSRD---RQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV 525
             E + S     S+ +       SEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV
Sbjct: 788  SESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV 847

Query: 526  DNQPEELVRSAED----------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQD 569
            DNQPEELVRSAED                +STVPTQPDNPFSHPDKLKRMSKSVPAFLQD
Sbjct: 848  DNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQD 907

Query: 570  ESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK 629
            ESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK
Sbjct: 908  ESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK 967

Query: 630  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 689
            GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK
Sbjct: 968  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027

Query: 690  KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 749
            KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ
Sbjct: 1028 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 1087

Query: 750  LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 809
            LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG
Sbjct: 1088 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 1147

Query: 810  SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH 869
            SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH
Sbjct: 1148 SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH 1207

Query: 870  YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI 929
            YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI
Sbjct: 1208 YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI 1267

Query: 930  AKISK 934
            AKISK
Sbjct: 1268 AKISK 1272


>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
          Length = 376

 Score =  760 bits (1963), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 559 MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 618
           MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV
Sbjct: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60

Query: 619 YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 678
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120

Query: 679 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 738
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180

Query: 739 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 798
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240

Query: 799 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 858
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300

Query: 859 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 918
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360

Query: 919 EATLPLRMLLIAKISK 934
           EATLPLRMLLIAKISK
Sbjct: 361 EATLPLRMLLIAKISK 376


>gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
          Length = 376

 Score =  760 bits (1963), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 559 MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 618
           MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV
Sbjct: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60

Query: 619 YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 678
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120

Query: 679 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 738
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180

Query: 739 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 798
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240

Query: 799 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 858
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300

Query: 859 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 918
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360

Query: 919 EATLPLRMLLIAKISK 934
           EATLPLRMLLIAKISK
Sbjct: 361 EATLPLRMLLIAKISK 376


>gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
          Length = 365

 Score =  738 bits (1904), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 571 SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 630
           SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG
Sbjct: 2   SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 61

Query: 631 NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 690
           NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK
Sbjct: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121

Query: 691 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 750
           TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL
Sbjct: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181

Query: 751 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 810
           RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS
Sbjct: 182 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 241

Query: 811 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 870
           HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY
Sbjct: 242 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 301

Query: 871 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 930
           KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA
Sbjct: 302 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 361

Query: 931 KISK 934
           KISK
Sbjct: 362 KISK 365


>gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
          Length = 336

 Score =  667 bits (1720), Expect = 0.0
 Identities = 336/376 (89%), Positives = 336/376 (89%), Gaps = 40/376 (10%)

Query: 559 MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 618
           MSKSVPAFLQDE                                        VSGSVMSV
Sbjct: 1   MSKSVPAFLQDE----------------------------------------VSGSVMSV 20

Query: 619 YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 678
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 21  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 80

Query: 679 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 738
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 81  KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 140

Query: 739 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 798
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 141 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 200

Query: 799 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 858
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 201 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 260

Query: 859 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 918
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 261 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 320

Query: 919 EATLPLRMLLIAKISK 934
           EATLPLRMLLIAKISK
Sbjct: 321 EATLPLRMLLIAKISK 336


>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
          Length = 550

 Score =  330 bits (847), Expect = 3e-90
 Identities = 184/446 (41%), Positives = 265/446 (59%), Gaps = 20/446 (4%)

Query: 483 DRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVSTV 542
           D+  G + E    +K  E       P  ++++   +   + +  + PEE  ++ ED    
Sbjct: 115 DQAPGHDREAEAAVKEKEEGPE---PRLTIDEAPQERLRETEASD-PEEASQAQED---- 166

Query: 543 PTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTN-LSS 601
           P Q D      +    +  +     +      +T  AS+             SL   LSS
Sbjct: 167 PGQGDQQVCAEEADPELEPASGGEQEPRPQQAQTKAASQILENGEEAPGPDPSLDRMLSS 226

Query: 602 SSGMTSLSS--VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAAD 659
           SS ++SL+S  +SGS MS+ SGD   ++V+G++ FA+ Y     EL V V QC+ LAAA 
Sbjct: 227 SSSVSSLNSSTLSGSQMSL-SGDAEAVQVRGSVHFALHYEPGAAELRVHVIQCQGLAAA- 284

Query: 660 VKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIW 719
            +++RSDPYVK+YLLPDK    K+KT V K+ LNPV+NE LRY + +  L+ + L+LS+W
Sbjct: 285 -RRRRSDPYVKSYLLPDK--QSKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVW 341

Query: 720 HRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYV 779
           HR++  RN FLGEVE+ L+TWDW ++      W PL+ +  P   +  +RG + L+L+YV
Sbjct: 342 HRESLGRNIFLGEVEVPLDTWDWGSEPT----WLPLQPRVPPSPDDLPSRGLLALSLKYV 397

Query: 780 PEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTT 839
           P    G  LP +GE+H WVKE  DL  LR   L+++V+C +LPD S+ SRQ+TR V ++ 
Sbjct: 398 PAGSEGAGLPPSGELHFWVKEARDLLPLRAGSLDTYVQCFVLPDDSQASRQRTRVVRRSL 457

Query: 840 NPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDS 899
           +P+FNHTMVYDGF P DL +AC EL++WDH  L N+ LGG R+  GTG SYG +V WMDS
Sbjct: 458 SPVFNHTMVYDGFGPADLRQACAELSLWDHGALANRQLGGTRLSLGTGSSYGLQVPWMDS 517

Query: 900 TSEEVALWEKMVNSPNTWIEATLPLR 925
           T EE  LW+ ++  P  W++  LPLR
Sbjct: 518 TPEEKQLWQALLEQPCEWVDGLLPLR 543



 Score = 94.0 bits (232), Expect = 6e-19
 Identities = 68/236 (28%), Positives = 116/236 (49%), Gaps = 10/236 (4%)

Query: 1   MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60
           ++DLSFLTEEEQEAI  VLQRDA L++ EE RV  L   + D  QLK ++G WF EA+++
Sbjct: 31  LLDLSFLTEEEQEAIAGVLQRDARLRQLEEGRVSKLRASVADPGQLKILTGDWFQEARSQ 90

Query: 61  RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP 120
           RH +   G+D++RASMR+K+     +Q+   +  A+ +      K+    PE    ++E 
Sbjct: 91  RHHNAHFGSDLVRASMRRKK-STRGDQAPGHDREAEAA-----VKEKEEGPEPRLTIDEA 144

Query: 121 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTK--N 178
            ++    + +S     + +  D  Q + +      +    P +  +        QTK  +
Sbjct: 145 PQERLRETEASDPEEASQAQEDPGQGDQQVCAEEADPELEPASGGEQEPRPQQAQTKAAS 204

Query: 179 EQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPI 234
           +  +NG          D +  S   S+V+  +   L  S+ +L G +   Q++  +
Sbjct: 205 QILENGEEAPGPDPSLDRMLSS--SSSVSSLNSSTLSGSQMSLSGDAEAVQVRGSV 258


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  298 bits (762), Expect = 2e-80
 Identities = 169/409 (41%), Positives = 246/409 (60%), Gaps = 25/409 (6%)

Query: 528 QPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLS 587
           +P E  +S  D+     +P++       L   SKSVP    D  ++ E +   +   +L 
Sbjct: 267 RPSEYTKSVIDL-----RPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEEDI-DHLVKLH 320

Query: 588 RHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKEL 645
           R K + SS+ + SS S +       GS+MS+YS  GDFGN+ V G I F+++Y +  + L
Sbjct: 321 RQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSL 373

Query: 646 HVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIE 705
            V V +C  LA AD  K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y+E LRY+I 
Sbjct: 374 VVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIP 433

Query: 706 KQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALE 765
           + +L  + L  S+WH   F RN+FLGE E+ +++W  D K +  L  +      +P  L 
Sbjct: 434 ESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLP 493

Query: 766 AENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR-GSHLNSFVK 817
           + ++GE+ ++L+Y+P    PV G +  +     GE+ +W+KE  +L   + G   +SFVK
Sbjct: 494 S-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552

Query: 818 CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQF 876
             +LP  ++ S++KT  + KT NP +NHT VY+G R EDL   C+ELTVWD   L +N F
Sbjct: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612

Query: 877 LGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 925
           LGG+R+G GTG S G  VDWMDST EEV+LW+KM   P +W E TL LR
Sbjct: 613 LGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 54/244 (22%), Positives = 100/244 (40%), Gaps = 18/244 (7%)

Query: 1   MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60
           ++DLSFL+EEE++ I+ VLQRD  +++A+E+R+R L  ++ + ++     G   Y  +  
Sbjct: 4   LLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTC 63

Query: 61  RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENG--------AKESWVNNVNKDAFLPPE 112
               +  G    + +  +    +     + +E+         AKE  +     D F   +
Sbjct: 64  ARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYDQK 123

Query: 113 LAGVVEEPEEDAAPAS-PSSSVVNPASSVIDMSQENTRKPNVSP------EKRKNP---F 162
           +         +    S      V+   +V       T+  ++ P      E++K P   F
Sbjct: 124 VNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLF 183

Query: 163 NSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLP 222
              KL  G S+ + ++E   +       TS+ D L +S         S  K +  K+T P
Sbjct: 184 EVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQP 243

Query: 223 GLSN 226
           G  N
Sbjct: 244 GGQN 247


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  298 bits (762), Expect = 2e-80
 Identities = 169/409 (41%), Positives = 246/409 (60%), Gaps = 25/409 (6%)

Query: 528 QPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLS 587
           +P E  +S  D+     +P++       L   SKSVP    D  ++ E +   +   +L 
Sbjct: 267 RPSEYTKSVIDL-----RPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEEDI-DHLVKLH 320

Query: 588 RHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKEL 645
           R K + SS+ + SS S +       GS+MS+YS  GDFGN+ V G I F+++Y +  + L
Sbjct: 321 RQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSL 373

Query: 646 HVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIE 705
            V V +C  LA AD  K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y+E LRY+I 
Sbjct: 374 VVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIP 433

Query: 706 KQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALE 765
           + +L  + L  S+WH   F RN+FLGE E+ +++W  D K +  L  +      +P  L 
Sbjct: 434 ESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLP 493

Query: 766 AENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR-GSHLNSFVK 817
           + ++GE+ ++L+Y+P    PV G +  +     GE+ +W+KE  +L   + G   +SFVK
Sbjct: 494 S-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552

Query: 818 CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQF 876
             +LP  ++ S++KT  + KT NP +NHT VY+G R EDL   C+ELTVWD   L +N F
Sbjct: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612

Query: 877 LGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 925
           LGG+R+G GTG S G  VDWMDST EEV+LW+KM   P +W E TL LR
Sbjct: 613 LGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 54/244 (22%), Positives = 100/244 (40%), Gaps = 18/244 (7%)

Query: 1   MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60
           ++DLSFL+EEE++ I+ VLQRD  +++A+E+R+R L  ++ + ++     G   Y  +  
Sbjct: 4   LLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTC 63

Query: 61  RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENG--------AKESWVNNVNKDAFLPPE 112
               +  G    + +  +    +     + +E+         AKE  +     D F   +
Sbjct: 64  ARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYDQK 123

Query: 113 LAGVVEEPEEDAAPAS-PSSSVVNPASSVIDMSQENTRKPNVSP------EKRKNP---F 162
           +         +    S      V+   +V       T+  ++ P      E++K P   F
Sbjct: 124 VNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLF 183

Query: 163 NSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLP 222
              KL  G S+ + ++E   +       TS+ D L +S         S  K +  K+T P
Sbjct: 184 EVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQP 243

Query: 223 GLSN 226
           G  N
Sbjct: 244 GGQN 247


>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  271 bits (692), Expect = 3e-72
 Identities = 202/622 (32%), Positives = 314/622 (50%), Gaps = 80/622 (12%)

Query: 355 EFSVLESDRLKNG-MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSG 413
           + +VL +D ++   +  +   EE QS  +  Q  +     +S +SP   K  +H      
Sbjct: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAE-----KSDTSPVAGKKASHDGPKRK 184

Query: 414 SFPINGLHS--HSEVLTARP---------------QSMENSPTINEPKDKSSELTRLESV 456
            F ++   S    E++T +                +S+++ P  +     SS+L   E  
Sbjct: 185 GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPG 244

Query: 457 LPRSPADELSHCVEPEPSQVPGGSSR------DRQQGSEEEPSPVLKTLERSAARKMPSK 510
            PR+P    S+ V P     P  S+R       R+ G E   S  L  +E   ++++   
Sbjct: 245 -PRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFEN--SMDLAAIE-GTSQELTKS 300

Query: 511 SLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE 570
              + S   S      +   +  RS  D+S   T+        D +   SKSVP  L  +
Sbjct: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSE-----DTVSIRSKSVPGALDKD 355

Query: 571 S-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLE 627
           S ++ E    +  S QLS      ++   L+S    TSL+S+    MSVYS  GD+GN++
Sbjct: 356 SLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM----MSVYSETGDYGNVK 405

Query: 628 VKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLV 687
           V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +  K+KT +
Sbjct: 406 VSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKI 465

Query: 688 VKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQN 747
              T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++W+++N  +
Sbjct: 466 RTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTD 524

Query: 748 KQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK--------- 787
           +   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K         
Sbjct: 525 E---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKE 580

Query: 788 --LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFN 844
             + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + K+ NP +N
Sbjct: 581 SPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWN 640

Query: 845 HTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEE 903
           HT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VDWMDS  EE
Sbjct: 641 HTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEE 700

Query: 904 VALWEKMVNSPNTWIEATLPLR 925
             LW+KM N+P T  E  L LR
Sbjct: 701 QRLWQKMANNPGTPFEGVLMLR 722



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 31/262 (11%)

Query: 45  QLKNMSGQWFYEAKAKRHRD-KIHGADIIRASMRKKRPQIAAEQSKDR-ENGAKESWVNN 102
           QL+ ++G+WF+E KAKR +   + G D++R S+ ++ P     QS+++    A++S  + 
Sbjct: 111 QLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSP 170

Query: 103 V--NKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSV-----IDMSQENTRKPNVSP 155
           V   K +   P+  G +      A        ++ P +       +D+  ++ R     P
Sbjct: 171 VAGKKASHDGPKRKGFLLSKFRSAT----RGEIITPKTDTGRSYSLDLDGQHFRSLKSPP 226

Query: 156 EKRKNPFNSSKLPEGHSSQQTKNEQSKNG-------------RTGLFQTSKEDELSESKE 202
              +    SS L +     +T      NG             RT     S+E     S +
Sbjct: 227 GSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMD 286

Query: 203 KSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDS 262
            + +  TS Q+L KS +     ++G+   A    +       ++L+  ++ +   + T S
Sbjct: 287 LAAIEGTS-QELTKSHRR---NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVS 342

Query: 263 LKARGAPRGILKRNSSSSSTDS 284
           ++++  P G L ++S   + +S
Sbjct: 343 IRSKSVP-GALDKDSLEETEES 363



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 3/56 (5%)

Query: 2  IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEA 57
          I+LSFL + E+E I+ VL+RD  LK+ E++R+R L  ++    + K  SG+   EA
Sbjct: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNEL---LEAKRRSGKTQQEA 60


>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  271 bits (692), Expect = 3e-72
 Identities = 202/622 (32%), Positives = 314/622 (50%), Gaps = 80/622 (12%)

Query: 355 EFSVLESDRLKNG-MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSG 413
           + +VL +D ++   +  +   EE QS  +  Q  +     +S +SP   K  +H      
Sbjct: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAE-----KSDTSPVAGKKASHDGPKRK 184

Query: 414 SFPINGLHS--HSEVLTARP---------------QSMENSPTINEPKDKSSELTRLESV 456
            F ++   S    E++T +                +S+++ P  +     SS+L   E  
Sbjct: 185 GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPG 244

Query: 457 LPRSPADELSHCVEPEPSQVPGGSSR------DRQQGSEEEPSPVLKTLERSAARKMPSK 510
            PR+P    S+ V P     P  S+R       R+ G E   S  L  +E   ++++   
Sbjct: 245 -PRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFEN--SMDLAAIE-GTSQELTKS 300

Query: 511 SLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE 570
              + S   S      +   +  RS  D+S   T+        D +   SKSVP  L  +
Sbjct: 301 HRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSE-----DTVSIRSKSVPGALDKD 355

Query: 571 S-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLE 627
           S ++ E    +  S QLS      ++   L+S    TSL+S+    MSVYS  GD+GN++
Sbjct: 356 SLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM----MSVYSETGDYGNVK 405

Query: 628 VKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLV 687
           V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +  K+KT +
Sbjct: 406 VSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKI 465

Query: 688 VKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQN 747
              T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++W+++N  +
Sbjct: 466 RTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTD 524

Query: 748 KQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK--------- 787
           +   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K         
Sbjct: 525 E---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKE 580

Query: 788 --LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFN 844
             + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + K+ NP +N
Sbjct: 581 SPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWN 640

Query: 845 HTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEE 903
           HT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VDWMDS  EE
Sbjct: 641 HTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEE 700

Query: 904 VALWEKMVNSPNTWIEATLPLR 925
             LW+KM N+P T  E  L LR
Sbjct: 701 QRLWQKMANNPGTPFEGVLMLR 722



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 31/262 (11%)

Query: 45  QLKNMSGQWFYEAKAKRHRD-KIHGADIIRASMRKKRPQIAAEQSKDR-ENGAKESWVNN 102
           QL+ ++G+WF+E KAKR +   + G D++R S+ ++ P     QS+++    A++S  + 
Sbjct: 111 QLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSP 170

Query: 103 V--NKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSV-----IDMSQENTRKPNVSP 155
           V   K +   P+  G +      A        ++ P +       +D+  ++ R     P
Sbjct: 171 VAGKKASHDGPKRKGFLLSKFRSAT----RGEIITPKTDTGRSYSLDLDGQHFRSLKSPP 226

Query: 156 EKRKNPFNSSKLPEGHSSQQTKNEQSKNG-------------RTGLFQTSKEDELSESKE 202
              +    SS L +     +T      NG             RT     S+E     S +
Sbjct: 227 GSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMD 286

Query: 203 KSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDS 262
            + +  TS Q+L KS +     ++G+   A    +       ++L+  ++ +   + T S
Sbjct: 287 LAAIEGTS-QELTKSHRR---NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVS 342

Query: 263 LKARGAPRGILKRNSSSSSTDS 284
           ++++  P G L ++S   + +S
Sbjct: 343 IRSKSVP-GALDKDSLEETEES 363



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 3/56 (5%)

Query: 2  IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEA 57
          I+LSFL + E+E I+ VL+RD  LK+ E++R+R L  ++    + K  SG+   EA
Sbjct: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNEL---LEAKRRSGKTQQEA 60


>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score =  270 bits (689), Expect = 6e-72
 Identities = 197/630 (31%), Positives = 307/630 (48%), Gaps = 74/630 (11%)

Query: 355 EFSVLESDRLKNG-MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSG 413
           + +VL +D ++   +  +   EE QS  +  Q  +     +S +SP   K  +H      
Sbjct: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAE-----KSDTSPVAGKKASHDGPKRK 184

Query: 414 SFPINGLHS--HSEVLTARP---------------QSMENSPTINEPKDKSSELTRLESV 456
            F ++   S    E++T +                +S+++ P  +     SS+L   E  
Sbjct: 185 GFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPG 244

Query: 457 LPRSPADELSHCVEPEPSQVPGGSSR------DRQQGSE--------EEPSPVLKTLERS 502
            PR+P    S+ V P     P  S+R       R+ G E        E  S  L    R 
Sbjct: 245 -PRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRR 303

Query: 503 AARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKS 562
                PS ++   S  S       +  E     +ED  ++ ++        D L+   +S
Sbjct: 304 NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETEES 363

Query: 563 VPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNL-SSSSGMTSLSSVSGSVMSVYS- 620
           + A +  +        AS  S           +  N+  + S  TSL+S+    MSVYS 
Sbjct: 364 IDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSM----MSVYSE 419

Query: 621 -GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 679
            GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +
Sbjct: 420 TGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSR 479

Query: 680 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLET 739
             K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++
Sbjct: 480 NNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDS 538

Query: 740 WDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK- 787
           W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K 
Sbjct: 539 WNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKT 594

Query: 788 ----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVG 836
                     + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + 
Sbjct: 595 FKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIK 654

Query: 837 KTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVD 895
           K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VD
Sbjct: 655 KSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVD 714

Query: 896 WMDSTSEEVALWEKMVNSPNTWIEATLPLR 925
           WMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 715 WMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 55/262 (20%), Positives = 111/262 (42%), Gaps = 31/262 (11%)

Query: 45  QLKNMSGQWFYEAKAKRHRD-KIHGADIIRASMRKKRPQIAAEQSKDR-ENGAKESWVNN 102
           QL+ ++G+WF+E KAKR +   + G D++R S+ ++ P     QS+++    A++S  + 
Sbjct: 111 QLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSP 170

Query: 103 V--NKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSV-----IDMSQENTRKPNVSP 155
           V   K +   P+  G +      A        ++ P +       +D+  ++ R     P
Sbjct: 171 VAGKKASHDGPKRKGFLLSKFRSAT----RGEIITPKTDTGRSYSLDLDGQHFRSLKSPP 226

Query: 156 EKRKNPFNSSKLPEGHSSQQTKNEQSKNG-------------RTGLFQTSKEDELSESKE 202
              +    SS L +     +T      NG             RT     S+E     S +
Sbjct: 227 GSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMD 286

Query: 203 KSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDS 262
            + +  TS Q+L KS +     ++G+   A    +       ++L+  ++ +   + T S
Sbjct: 287 LAAIEGTS-QELTKSHRR---NTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVS 342

Query: 263 LKARGAPRGILKRNSSSSSTDS 284
           ++++  P G L ++S   + +S
Sbjct: 343 IRSKSVP-GALDKDSLEETEES 363



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 3/56 (5%)

Query: 2  IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEA 57
          I+LSFL + E+E I+ VL+RD  LK+ E++R+R L  ++    + K  SG+   EA
Sbjct: 8  INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNEL---LEAKRRSGKTQQEA 60


>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
          Length = 542

 Score =  195 bits (496), Expect = 1e-49
 Identities = 132/411 (32%), Positives = 208/411 (50%), Gaps = 26/411 (6%)

Query: 531 ELVRSAEDVSTV----PTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQL 586
           +L++S + +S +    PT P    S   +      S P  L+  + + +   ++    + 
Sbjct: 140 QLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDILKPLNQE-DPKCSTNPILKQ 198

Query: 587 SRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELH 646
                SP+  T  S      SL S+  +   +  G+F N  V G I+FAI Y      L 
Sbjct: 199 QNLPSSPAPSTIFSGGFRHGSLISIDSTCTEM--GNFDNANVTGEIEFAIHYCFKTHSLE 256

Query: 647 VFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEK 706
           + +  CK+LA  + KK++ +PYVK YLLPD+   GK+KT V + T++P + E L+Y++  
Sbjct: 257 ICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAP 316

Query: 707 QILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA 766
             L T++L +S+WH  T  R  FLGEV + L TWD+++   +  RW+PL+ K        
Sbjct: 317 AQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSV 376

Query: 767 -ENRGEM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFV 816
            ++ GE+    KL L   P    E   G   P+  G++ + V    +LP+     LNSFV
Sbjct: 377 PQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFV 436

Query: 817 K-CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLT 873
           K C  LPD  +K R K+  + K   P + H+ V+ G  P  L ++ +ELTVWD   + + 
Sbjct: 437 KGCLTLPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMN 495

Query: 874 NQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 924
           ++ LGG R+G     S G      D+ S     W+K+++SPN W + TL L
Sbjct: 496 DRLLGGTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 23/57 (40%), Positives = 34/57 (59%)

Query: 2  IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAK 58
          IDLS L E E+EAI++VL RD A++  EEER R L   ++  +     +  W ++ K
Sbjct: 5  IDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEK 61


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  114 bits (286), Expect = 3e-25
 Identities = 120/521 (23%), Positives = 213/521 (40%), Gaps = 78/521 (14%)

Query: 454 ESVLPRSPADELSHCVEPEPSQVPG-GSSRDRQ-QGSEEEPSPVLKT--------LERSA 503
           E   P  PA E  H     P++ P  G S DR+  G +  P P            + R++
Sbjct: 183 EPAAPEQPAPEPKH-----PARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRAS 237

Query: 504 ARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDV-----------STVPTQPDNPFS- 551
             +M S S +  S D S  A   ++    +R A  V           S  P QP  P + 
Sbjct: 238 EARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTP 297

Query: 552 ------------HPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKS-PSSLTN 598
                        PD+   ++ S P       ++R        +      + S PS   +
Sbjct: 298 GGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYS 357

Query: 599 LSSSSGMTSLSS-----VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCK 653
            +S++     ++              S D       G ++F++ Y +    L   + + K
Sbjct: 358 QASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAK 417

Query: 654 DLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYK-IEKQILKTQ 712
            L   D     +DPYVK +LLP   K  K +T  ++ T NP++NE L Y  I  + ++ +
Sbjct: 418 GLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRK 476

Query: 713 KLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL---RWYPLKR-----KTAPVAL 764
            L +S+   D F  N F+GE    L+    + ++N  +   R  P+KR         +AL
Sbjct: 477 TLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMAL 536

Query: 765 ----------EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLL-RGSHLN 813
                     + E RG++ ++L Y  +          G + + +  C+ L  +    + +
Sbjct: 537 YEEEQVERVGDIEERGKILVSLMYSTQ---------QGGLIVGIIRCVHLAAMDANGYSD 587

Query: 814 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH-YKL 872
            FVK  + PD  +K++ KT+   KT NP FN    YD  +  DL +  ++++VWD+    
Sbjct: 588 PFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGK 646

Query: 873 TNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALWEKMVN 912
           +N ++GG ++G    G+      + + +  +++  W ++ N
Sbjct: 647 SNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQN 687



 Score = 83.6 bits (205), Expect = 8e-16
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)

Query: 624 GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 683
           G++E +G I  ++ Y      L V + +C  LAA D     SDP+VK +L PD GK  K 
Sbjct: 546 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 604

Query: 684 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 736
           KT + KKTLNP +NE   Y I+   L  + L++S+W  D  K N ++G  +L        
Sbjct: 605 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 664

Query: 737 LETW--DWDNKQNKQLRWYPLKRK 758
           L+ W     NK  K  RW+ L+ +
Sbjct: 665 LKHWYECLKNKDKKIERWHQLQNE 688



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 57/266 (21%), Positives = 100/266 (37%), Gaps = 40/266 (15%)

Query: 7   LTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKI 66
           LT+EE+E I +V+ R   ++  E+ER+  L +++  +   KN++G           +  +
Sbjct: 50  LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRL--ENMRKNVAGDGVNRCILCGEQLGM 107

Query: 67  HGADIIRASMRKKRP------------------QIAAEQSKD-RENGAKESWVNNVNKDA 107
            G+  +     KK                    +I  EQ +  + +GA   W        
Sbjct: 108 LGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGA---WFFKGFPKQ 164

Query: 108 FLPPELAGVVEEPE----EDAAPASPSSSVVNPASSVIDMSQENTRKP--NVSPEKRKNP 161
            LP  +     +P+    E AAP  P+    +PA +      E+ R P     P+    P
Sbjct: 165 VLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAP 224

Query: 162 FNSSKLP------EGHSSQQTKNEQSKNGRTGLFQTSKED---ELSESKEKSTVADTSIQ 212
              +  P      E   S  +++ +S +   G   +S+       + S + S  A  S+Q
Sbjct: 225 GRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQ 284

Query: 213 KLEKSKQTLPGLSNGSQIKAPIPKAR 238
                +   PG   GS+   P P  R
Sbjct: 285 SPAPPQPGQPGTPGGSR-PGPGPAGR 309


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  114 bits (286), Expect = 3e-25
 Identities = 120/521 (23%), Positives = 213/521 (40%), Gaps = 78/521 (14%)

Query: 454 ESVLPRSPADELSHCVEPEPSQVPG-GSSRDRQ-QGSEEEPSPVLKT--------LERSA 503
           E   P  PA E  H     P++ P  G S DR+  G +  P P            + R++
Sbjct: 179 EPAAPEQPAPEPKH-----PARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRAS 233

Query: 504 ARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDV-----------STVPTQPDNPFS- 551
             +M S S +  S D S  A   ++    +R A  V           S  P QP  P + 
Sbjct: 234 EARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTP 293

Query: 552 ------------HPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKS-PSSLTN 598
                        PD+   ++ S P       ++R        +      + S PS   +
Sbjct: 294 GGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYS 353

Query: 599 LSSSSGMTSLSS-----VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCK 653
            +S++     ++              S D       G ++F++ Y +    L   + + K
Sbjct: 354 QASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAK 413

Query: 654 DLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYK-IEKQILKTQ 712
            L   D     +DPYVK +LLP   K  K +T  ++ T NP++NE L Y  I  + ++ +
Sbjct: 414 GLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRK 472

Query: 713 KLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL---RWYPLKR-----KTAPVAL 764
            L +S+   D F  N F+GE    L+    + ++N  +   R  P+KR         +AL
Sbjct: 473 TLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMAL 532

Query: 765 ----------EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLL-RGSHLN 813
                     + E RG++ ++L Y  +          G + + +  C+ L  +    + +
Sbjct: 533 YEEEQVERVGDIEERGKILVSLMYSTQ---------QGGLIVGIIRCVHLAAMDANGYSD 583

Query: 814 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH-YKL 872
            FVK  + PD  +K++ KT+   KT NP FN    YD  +  DL +  ++++VWD+    
Sbjct: 584 PFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGK 642

Query: 873 TNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALWEKMVN 912
           +N ++GG ++G    G+      + + +  +++  W ++ N
Sbjct: 643 SNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQN 683



 Score = 83.6 bits (205), Expect = 8e-16
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)

Query: 624 GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 683
           G++E +G I  ++ Y      L V + +C  LAA D     SDP+VK +L PD GK  K 
Sbjct: 542 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 600

Query: 684 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 736
           KT + KKTLNP +NE   Y I+   L  + L++S+W  D  K N ++G  +L        
Sbjct: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660

Query: 737 LETW--DWDNKQNKQLRWYPLKRK 758
           L+ W     NK  K  RW+ L+ +
Sbjct: 661 LKHWYECLKNKDKKIERWHQLQNE 684



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 57/266 (21%), Positives = 100/266 (37%), Gaps = 40/266 (15%)

Query: 7   LTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKI 66
           LT+EE+E I +V+ R   ++  E+ER+  L +++  +   KN++G           +  +
Sbjct: 46  LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRL--ENMRKNVAGDGVNRCILCGEQLGM 103

Query: 67  HGADIIRASMRKKRP------------------QIAAEQSKD-RENGAKESWVNNVNKDA 107
            G+  +     KK                    +I  EQ +  + +GA   W        
Sbjct: 104 LGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGA---WFFKGFPKQ 160

Query: 108 FLPPELAGVVEEPE----EDAAPASPSSSVVNPASSVIDMSQENTRKP--NVSPEKRKNP 161
            LP  +     +P+    E AAP  P+    +PA +      E+ R P     P+    P
Sbjct: 161 VLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAP 220

Query: 162 FNSSKLP------EGHSSQQTKNEQSKNGRTGLFQTSKED---ELSESKEKSTVADTSIQ 212
              +  P      E   S  +++ +S +   G   +S+       + S + S  A  S+Q
Sbjct: 221 GRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQ 280

Query: 213 KLEKSKQTLPGLSNGSQIKAPIPKAR 238
                +   PG   GS+   P P  R
Sbjct: 281 SPAPPQPGQPGTPGGSR-PGPGPAGR 305


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  112 bits (280), Expect = 2e-24
 Identities = 114/454 (25%), Positives = 206/454 (45%), Gaps = 53/454 (11%)

Query: 482 RDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVD------NQPEELVRS 535
           R+++  S    +P L+ L+  + R   +  L+D S+    +A V       + P E+  S
Sbjct: 4   RNKEASSPSSANPPLEALQSPSFRGNMADKLKDPSTLGFLEAAVKISHTSPDIPAEVQMS 63

Query: 536 AEDVSTVPTQPDNPFSHPDKLKR---MSKSVPAFLQDESDD--RETDTASESSYQLSRHK 590
            ++     T+     + P    R     + +P  +   S D   E   A+E    + R K
Sbjct: 64  VKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRIK 123

Query: 591 KSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVA 650
                L    S  G  + S  + S               G I F++ Y    + L V + 
Sbjct: 124 PE---LYKQKSVDGEDAKSEATKSC--------------GKINFSLRYDYETETLIVRIL 166

Query: 651 QCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILK 710
           +  DL A D     SDPYVK YLLPD+    K +T V +KTLNP ++E   + +  + L 
Sbjct: 167 KAFDLPAKDFCGS-SDPYVKIYLLPDR--KCKLQTRVHRKTLNPTFDENFHFPVPYEELA 223

Query: 711 TQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRG 770
            +KL+LS++  D F R+  +GEV LD   ++  +   +   W  ++  T+    E+ + G
Sbjct: 224 DRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRETSIWKDIQYATS----ESVDLG 278

Query: 771 EMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSR 829
           E+  +L Y         LPT G + + V +C +L  +    + + +VK ++L D  R  +
Sbjct: 279 EIMFSLCY---------LPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKK 329

Query: 830 QKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGF---G 885
           +KT     T NP++N  +++D   PE++ +  + ++V D+ ++  N+ +G  R+G    G
Sbjct: 330 KKTTIKKNTLNPVYNEAIIFD-IPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEG 388

Query: 886 TGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIE 919
            G+ +  E+  +    + +A W  +V    ++ E
Sbjct: 389 LGRDHWNEM--LAYPRKPIAHWHSLVEVKKSFKE 420


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 2e-24
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 620 SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 679
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 680 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 737
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 738 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 797
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 798 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 856
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 857 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 911
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 2e-24
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 620 SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 679
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 680 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 737
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 738 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 797
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 798 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 856
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 857 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 911
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 2e-24
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 620 SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 679
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 680 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 737
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 738 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 797
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 798 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 856
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 857 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 911
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  110 bits (275), Expect = 6e-24
 Identities = 89/299 (29%), Positives = 150/299 (50%), Gaps = 30/299 (10%)

Query: 630 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 689
           G +QF+++Y     +L V V Q  +L A D+    SDPYVK +LLPDK K  K +T V +
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197

Query: 690 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 749
           KTLNP +NE   +K+  Q L  + L ++I+  D F ++  +GEV++ + T D      + 
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256

Query: 750 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 808
             W  L+        E E  G++  +L+YV         PT G++ + + E  +L  +  
Sbjct: 257 --WRDLQGGEKE---EPEKLGDICTSLRYV---------PTAGKLTVCILEAKNLKKMDV 302

Query: 809 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 868
           G   + +VK  ++ +  R  ++KT    KT NP FN +  ++    E + +  V +TV D
Sbjct: 303 GGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLD 361

Query: 869 HYKL-TNQFLGGLRIGFGTGKSYGTEV----DWMDSTSEEVALWEKMVNSPNTWIEATL 922
           + KL  N+ +G + +G     + GTE+    D + +    +A W  +   P   ++A L
Sbjct: 362 YDKLGKNEAIGKIFVG---SNATGTELRHWSDMLANPRRPIAQWHSL--KPEEEVDALL 415



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 627 EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 686
           E  G+I  ++ YV +  +L V + + K+L   DV    SDPYVK +L+ +  ++ KKKT 
Sbjct: 269 EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL-SDPYVKIHLMQNGKRLKKKKTT 327

Query: 687 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVEL-------DLET 739
           V KKTLNP +NE   ++I  + ++  ++ +++   D   +N  +G++ +       +L  
Sbjct: 328 VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRH 387

Query: 740 WD--WDNKQNKQLRWYPLKRKTAPVALEAENR 769
           W     N +    +W+ LK +    AL  +N+
Sbjct: 388 WSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  110 bits (275), Expect = 6e-24
 Identities = 89/299 (29%), Positives = 150/299 (50%), Gaps = 30/299 (10%)

Query: 630 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 689
           G +QF+++Y     +L V V Q  +L A D+    SDPYVK +LLPDK K  K +T V +
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197

Query: 690 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 749
           KTLNP +NE   +K+  Q L  + L ++I+  D F ++  +GEV++ + T D      + 
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256

Query: 750 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 808
             W  L+        E E  G++  +L+YV         PT G++ + + E  +L  +  
Sbjct: 257 --WRDLQGGEKE---EPEKLGDICTSLRYV---------PTAGKLTVCILEAKNLKKMDV 302

Query: 809 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 868
           G   + +VK  ++ +  R  ++KT    KT NP FN +  ++    E + +  V +TV D
Sbjct: 303 GGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLD 361

Query: 869 HYKL-TNQFLGGLRIGFGTGKSYGTEV----DWMDSTSEEVALWEKMVNSPNTWIEATL 922
           + KL  N+ +G + +G     + GTE+    D + +    +A W  +   P   ++A L
Sbjct: 362 YDKLGKNEAIGKIFVG---SNATGTELRHWSDMLANPRRPIAQWHSL--KPEEEVDALL 415



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 627 EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 686
           E  G+I  ++ YV +  +L V + + K+L   DV    SDPYVK +L+ +  ++ KKKT 
Sbjct: 269 EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL-SDPYVKIHLMQNGKRLKKKKTT 327

Query: 687 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVEL-------DLET 739
           V KKTLNP +NE   ++I  + ++  ++ +++   D   +N  +G++ +       +L  
Sbjct: 328 VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRH 387

Query: 740 WD--WDNKQNKQLRWYPLKRKTAPVALEAENR 769
           W     N +    +W+ LK +    AL  +N+
Sbjct: 388 WSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  107 bits (266), Expect = 7e-23
 Identities = 79/276 (28%), Positives = 144/276 (52%), Gaps = 25/276 (9%)

Query: 625 NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK 684
           ++++ G + F ++Y    + L V + +  DL A D     SDPYVK YLLPD+ K  K +
Sbjct: 228 DVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGT-SDPYVKMYLLPDRKK--KFQ 284

Query: 685 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDN 744
           T V +KTLNP+++E  ++ +    L  +KL+ S++  D F R+  +GEV LD   ++  +
Sbjct: 285 TRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILD-NLFEVSD 343

Query: 745 KQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL 804
              +   W  +   T     E+ + GE+  +L Y         LPT G + + V +C +L
Sbjct: 344 LSREATVWKDIHCATT----ESIDLGEIMFSLCY---------LPTAGRMTLTVIKCRNL 390

Query: 805 PL--LRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 862
               + GS  + +VK +++ +  R  ++KT     T NP++N  +++D   PE++ +  +
Sbjct: 391 KAMDITGSS-DPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFD-IPPENVDQVSL 448

Query: 863 ELTVWDHYKL-TNQFLGGLRIGF---GTGKSYGTEV 894
            + V D+ ++  N+ +G  R G    G G+ +  E+
Sbjct: 449 SIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEM 484


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  107 bits (266), Expect = 7e-23
 Identities = 79/291 (27%), Positives = 133/291 (45%), Gaps = 23/291 (7%)

Query: 630 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 689
           G + F++ Y +    LH  + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 128 GTLDFSLLYDQENNALHCTITKAKGLKPMD-HNGLADPYVKLHLLPGASKANKLRTKTLR 186

Query: 690 KTLNPVYNEILR-YKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 748
            TLNP +NE L  Y I  + +  + L +S+   D F+ N F+GE  + L+      K N 
Sbjct: 187 NTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKL----KPNH 242

Query: 749 QLRWYPLKRKTAPV----ALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL 804
              +     K  PV        E RG + ++L+Y  +            + + +  C  L
Sbjct: 243 TKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQ---------KQGLLVGIVRCAHL 293

Query: 805 PLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVE 863
             +    + + +VK  + PD  +KS+ KT    KT NP FN    Y+  +  DL +  +E
Sbjct: 294 AAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYE-IKHGDLAKKSLE 352

Query: 864 LTVWDH-YKLTNQFLGGLRIGF-GTGKSYGTEVDWMDSTSEEVALWEKMVN 912
           +TVWD+    +N F+GG+ +G    G+      D + +  + +  W  + +
Sbjct: 353 VTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTS 403



 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 54/140 (38%), Positives = 73/140 (52%), Gaps = 10/140 (7%)

Query: 625 NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK 684
           +LE +G I  +++Y    + L V + +C  LAA D     SDPYVK YL PD  K  K K
Sbjct: 263 SLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGY-SDPYVKTYLRPDVDKKSKHK 321

Query: 685 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD-------L 737
           T V KKTLNP +NE   Y+I+   L  + L +++W  D  K N F+G V L        L
Sbjct: 322 TAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERL 381

Query: 738 ETW--DWDNKQNKQLRWYPL 755
           + W     NK  +  RW+ L
Sbjct: 382 KHWFDCLKNKDKRIERWHTL 401


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  102 bits (255), Expect = 1e-21
 Identities = 103/432 (23%), Positives = 198/432 (45%), Gaps = 53/432 (12%)

Query: 505 RKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQ-PDNPFSHPDKLKRMSKSV 563
           R +PS S +D + +  N    +   +E   ++ED    PT  PD+      K+   S  +
Sbjct: 85  RGLPSGS-KDNNQEPLNYMDTETNEQE---NSEDFLDPPTPCPDSSM----KISHTSPDI 136

Query: 564 PAFLQDESDDR-------------ETDTASESSYQLSRHKKSPS-SLTNLSSSSGMTSLS 609
           P   Q    +               T +A  +S +   +  +P  ++  L     +T + 
Sbjct: 137 PLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIG 196

Query: 610 SVSGSVMSVYS-----GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQR 664
            +   +    S     G   N +  G + F ++Y   L++L V + +  +L A D     
Sbjct: 197 RIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGT- 255

Query: 665 SDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTF 724
           SDPYVK YLLPD+    K +T V +KTLNPV++E+  + +    L+ +KL+ S++  D F
Sbjct: 256 SDPYVKIYLLPDRKT--KHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRF 313

Query: 725 KRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVP 784
            R+  +G+V +D    D  +   + + W  ++     V  +  + GE+  +L Y      
Sbjct: 314 SRHDLIGQVVVD-HFLDLADFPRECILWKDIEY----VTNDNVDLGELMFSLCY------ 362

Query: 785 GKKLPTTGEVHIWVKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIF 843
              LPT G + I + +  +L  +  +  +  +VK +++ D  R  ++KT     T NP++
Sbjct: 363 ---LPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVY 419

Query: 844 NHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGT---GKSYGTEVDWMDS 899
           N  +V+D   PE++ +  + + V D+ ++  N+ +G  ++G      G+ + +E+  +  
Sbjct: 420 NEAIVFD-VPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEM--LSY 476

Query: 900 TSEEVALWEKMV 911
             + +A W  +V
Sbjct: 477 PRKPIAHWHSLV 488


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 2e-21
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 627 EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 686
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 687 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 746
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 747 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 806
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 807 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 865
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 866 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 914
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 2e-21
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 627 EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 686
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 687 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 746
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 747 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 806
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 807 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 865
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 866 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 914
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 2e-21
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 627 EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 686
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 687 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 746
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 747 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 806
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 807 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 865
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 866 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 914
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.126    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,344,584
Number of Sequences: 37866
Number of extensions: 1879278
Number of successful extensions: 8933
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 562
Number of HSP's that attempted gapping in prelim test: 7524
Number of HSP's gapped (non-prelim): 1844
length of query: 934
length of database: 18,247,518
effective HSP length: 112
effective length of query: 822
effective length of database: 14,006,526
effective search space: 11513364372
effective search space used: 11513364372
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.