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Search of human proteins with 24308440
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308440 family with sequence similarity 125, member A [Homo
sapiens]
(273 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308440 family with sequence similarity 125, member A [Homo ... 545 e-155
gi|58761488 hypothetical protein LOC89853 isoform 1 [Homo sapiens] 153 2e-37
gi|58761490 hypothetical protein LOC89853 isoform 2 [Homo sapiens] 94 1e-19
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 31 1.0
gi|21361861 Fanconi anemia complementation group D2 isoform a [H... 30 1.7
gi|50428935 BPY2 interacting protein 1 [Homo sapiens] 30 1.7
gi|42476320 sushi domain containing 1 [Homo sapiens] 30 2.3
gi|239751047 PREDICTED: hypothetical protein isoform 3 [Homo sap... 30 3.0
gi|239751045 PREDICTED: hypothetical protein isoform 2 [Homo sap... 30 3.0
gi|239751043 PREDICTED: hypothetical protein isoform 1 [Homo sap... 30 3.0
gi|239745488 PREDICTED: hypothetical protein XP_002343476 isofor... 30 3.0
gi|239745486 PREDICTED: hypothetical protein XP_002343475 isofor... 30 3.0
gi|239745484 PREDICTED: hypothetical protein XP_002343474 isofor... 30 3.0
gi|24111244 MAM domain containing glycosylphosphatidylinositol a... 29 3.9
gi|7661990 mastermind-like 1 [Homo sapiens] 29 5.0
gi|46409512 hypothetical protein LOC400359 [Homo sapiens] 28 6.6
gi|239750588 PREDICTED: hypothetical protein XP_002347440 [Homo ... 28 6.6
gi|239744885 PREDICTED: hypothetical protein XP_002344275 [Homo ... 28 6.6
gi|226874831 guanylate kinase 1 isoform a [Homo sapiens] 28 6.6
gi|114145479 neuroepithelial cell transforming gene 1 isoform 1 ... 28 8.6
>gi|24308440 family with sequence similarity 125, member A [Homo
sapiens]
Length = 273
Score = 545 bits (1404), Expect = e-155
Identities = 273/273 (100%), Positives = 273/273 (100%)
Query: 1 MDPVPGTDSAPLAGLAWSSASAPPPRGFSAISCTVEGAPASFGKSFAQKSGYFLCLSSLG 60
MDPVPGTDSAPLAGLAWSSASAPPPRGFSAISCTVEGAPASFGKSFAQKSGYFLCLSSLG
Sbjct: 1 MDPVPGTDSAPLAGLAWSSASAPPPRGFSAISCTVEGAPASFGKSFAQKSGYFLCLSSLG 60
Query: 61 SLENPQENVVADIQIVVDKSPLPLGFSPVCDPMDSKASVSKKKRMCVKLLPLGATDTAVF 120
SLENPQENVVADIQIVVDKSPLPLGFSPVCDPMDSKASVSKKKRMCVKLLPLGATDTAVF
Sbjct: 61 SLENPQENVVADIQIVVDKSPLPLGFSPVCDPMDSKASVSKKKRMCVKLLPLGATDTAVF 120
Query: 121 DVRLSGKTKTVPGYLRIGDMGGFAIWCKKAKAPRPVPKPRGLSRDMQGLSLDAASQPSKG 180
DVRLSGKTKTVPGYLRIGDMGGFAIWCKKAKAPRPVPKPRGLSRDMQGLSLDAASQPSKG
Sbjct: 121 DVRLSGKTKTVPGYLRIGDMGGFAIWCKKAKAPRPVPKPRGLSRDMQGLSLDAASQPSKG 180
Query: 181 GLLERTASRLGSRASTLRRNDSIYEASSLYGISAMDGVPFTLHPRFEGKSCSPLAFSAFG 240
GLLERTASRLGSRASTLRRNDSIYEASSLYGISAMDGVPFTLHPRFEGKSCSPLAFSAFG
Sbjct: 181 GLLERTASRLGSRASTLRRNDSIYEASSLYGISAMDGVPFTLHPRFEGKSCSPLAFSAFG 240
Query: 241 DLTIKSLADIEEEYNYGFVVEKTAAARLPPSVS 273
DLTIKSLADIEEEYNYGFVVEKTAAARLPPSVS
Sbjct: 241 DLTIKSLADIEEEYNYGFVVEKTAAARLPPSVS 273
>gi|58761488 hypothetical protein LOC89853 isoform 1 [Homo sapiens]
Length = 319
Score = 153 bits (386), Expect = 2e-37
Identities = 97/278 (34%), Positives = 149/278 (53%), Gaps = 16/278 (5%)
Query: 2 DPVPGTDSAPLAGLAWSSASAPPPRGFSAISCTVEGAPASFGKS--FAQKSGYFLCLSSL 59
+ +P T P+ G+ ++ P G+ ++ T +G A K F K +LC +
Sbjct: 40 EALPETSMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRS 99
Query: 60 GSLENPQ-ENVVADIQIVVDKSPLPLGFSPVCDPMDSKASVSKKKRMCVKLLPLGATDTA 118
S EN NV+ D++++ K LP+GF P+ + +D++ +KKR+C+K +P +T+ A
Sbjct: 100 FSKENSHLGNVLVDMKLIDIKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAA 159
Query: 119 VFDVRLSGKTKTV-PGYLRIGDMGGFAIWCKKAKAPRPVPKPRGLSRDMQGLSLDAASQP 177
+ D+R+ G+TK P Y IG++ IW + + VP+ S+ AAS P
Sbjct: 160 ICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGR----VPRNHDSSQPTTPSQSSAASTP 215
Query: 178 SKGGLLERTASRLGS--RASTLRRNDSIYEASSLYGISAMDGVPFTLHPRFEGKSCSPLA 235
+ L + L + R R D Y+ S+LY ISAMDGVPF + +F SC P +
Sbjct: 216 AP-NLPRHISLTLPATFRGRNSTRTDYEYQHSNLYAISAMDGVPFMISEKF---SCVPES 271
Query: 236 FSAFG--DLTIKSLADIEEEYNYGFVVEKTAAARLPPS 271
F +TIKSLA+IE+EY Y F E++AAARLPPS
Sbjct: 272 MQPFDLLGITIKSLAEIEKEYEYSFRTEQSAAARLPPS 309
>gi|58761490 hypothetical protein LOC89853 isoform 2 [Homo sapiens]
Length = 221
Score = 94.0 bits (232), Expect = 1e-19
Identities = 48/157 (30%), Positives = 85/157 (54%), Gaps = 4/157 (2%)
Query: 2 DPVPGTDSAPLAGLAWSSASAPPPRGFSAISCTVEGAPASFGKS--FAQKSGYFLCLSSL 59
+ +P T P+ G+ ++ P G+ ++ T +G A K F K +LC +
Sbjct: 40 EALPETSMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRS 99
Query: 60 GSLENPQ-ENVVADIQIVVDKSPLPLGFSPVCDPMDSKASVSKKKRMCVKLLPLGATDTA 118
S EN NV+ D++++ K LP+GF P+ + +D++ +KKR+C+K +P +T+ A
Sbjct: 100 FSKENSHLGNVLVDMKLIDIKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAA 159
Query: 119 VFDVRLSGKTKTV-PGYLRIGDMGGFAIWCKKAKAPR 154
+ D+R+ G+TK P Y IG++ IW + + PR
Sbjct: 160 ICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPR 196
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 31.2 bits (69), Expect = 1.0
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 9/70 (12%)
Query: 150 AKAPRPVPKPRGLSRDMQGLSLDAASQPSKGGLLERTASRLGSRASTL---RRNDSIYEA 206
A AP PK GLS+DM L + P+ G + + S++ S S + R D +++
Sbjct: 416 ACAPISSPKTNGLSKDMSSLHI----SPNSGNVTSASGSQMASGISLVSFNSRPDGMHQR 471
Query: 207 SSLYGISAMD 216
S Y +S+ D
Sbjct: 472 S--YSVSSAD 479
>gi|21361861 Fanconi anemia complementation group D2 isoform a [Homo
sapiens]
Length = 1471
Score = 30.4 bits (67), Expect = 1.7
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 10/67 (14%)
Query: 91 DPMDSKASVSKKKRMCVKLLPLGATDTAVFDVRLSGKTKTVPGYLRIGDMGGFAIWCKKA 150
D M S+AS SK + ++ P TD + + LS ++T+P Y ++C+
Sbjct: 1414 DDMSSQASKSKATEVSLQNPPESGTDGCILLIVLSWWSRTLPTY----------VYCQML 1463
Query: 151 KAPRPVP 157
P P P
Sbjct: 1464 LCPFPFP 1470
>gi|50428935 BPY2 interacting protein 1 [Homo sapiens]
Length = 1059
Score = 30.4 bits (67), Expect = 1.7
Identities = 53/200 (26%), Positives = 76/200 (38%), Gaps = 38/200 (19%)
Query: 38 APASFGKSFAQKSGYFLCLSSLGSLENPQENVVADIQIVVDKSPLPL------------G 85
APAS G S + LG+ E P +V + + D P+PL G
Sbjct: 756 APASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEG 815
Query: 86 F-----SPVCDPMDSKASVSKKKRMCVKLLPLGATDTAVFDVRLSGKTKTVPGYLRIGDM 140
F P+ DP+ + +C+ D + + + +T+ V +
Sbjct: 816 FGVPRHDPLPDPLKVPPPLPDPSSICM-------VDPEMLPPKTARQTENVSRTRK---- 864
Query: 141 GGFAIWCKKAKAPRPVP----KPRGLS-RDMQGLSLDAASQPS-KGGLLERTASRLGSRA 194
A +A AP+ P K +GL+ D L A S+PS KGG SR S
Sbjct: 865 -PLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGG--RAPLSRKSSTP 921
Query: 195 STLRRNDSIYEASSLYGISA 214
T R S ASS G+SA
Sbjct: 922 KTATRGPS-GSASSRPGVSA 940
>gi|42476320 sushi domain containing 1 [Homo sapiens]
Length = 747
Score = 30.0 bits (66), Expect = 2.3
Identities = 48/196 (24%), Positives = 71/196 (36%), Gaps = 28/196 (14%)
Query: 12 LAGLAWSSASAPPPRGFSAISCTVEGAPASFGKSFAQKSGYFLCLSSLGSLENPQENVVA 71
L GLA +A AP P G + E A Q+ G +C+ + G + N +
Sbjct: 20 LLGLARGAAGAPGPDGLDVCATCHEHATCQ------QREGKKICICNYGFVGNGRTQ--- 70
Query: 72 DIQIVVDKSPLPLGFSPVCDPMDSKASVSKKKRMCVKLLPLGATDTAVFDVRLSGKTKT- 130
VDK+ G + VC S + C+ L AT+ + G T
Sbjct: 71 ----CVDKNECQFGATLVCGNHTS-CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTD 125
Query: 131 -----VPGYLRIGDM-----GGFAIWCKKAKAPRPVPKPRGLSRDMQGLS-LDAASQPS- 178
V G R G G F +C PR P+P + D + +D + P
Sbjct: 126 IDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCGTPPEV 185
Query: 179 -KGGLLERTASRLGSR 193
G ++ S LGS+
Sbjct: 186 PDGYIIGNYTSSLGSQ 201
>gi|239751047 PREDICTED: hypothetical protein isoform 3 [Homo
sapiens]
Length = 196
Score = 29.6 bits (65), Expect = 3.0
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Query: 12 LAGLAWSSASAPPPRGFSAISCTVEGAPAS 41
L L W +S PP G SCT+ G PAS
Sbjct: 78 LMALGWPPSSPSPPSG-DCCSCTIGGTPAS 106
>gi|239751045 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 196
Score = 29.6 bits (65), Expect = 3.0
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Query: 12 LAGLAWSSASAPPPRGFSAISCTVEGAPAS 41
L L W +S PP G SCT+ G PAS
Sbjct: 78 LMALGWPPSSPSPPSG-DCCSCTIGGTPAS 106
>gi|239751043 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 196
Score = 29.6 bits (65), Expect = 3.0
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Query: 12 LAGLAWSSASAPPPRGFSAISCTVEGAPAS 41
L L W +S PP G SCT+ G PAS
Sbjct: 78 LMALGWPPSSPSPPSG-DCCSCTIGGTPAS 106
>gi|239745488 PREDICTED: hypothetical protein XP_002343476 isoform 3
[Homo sapiens]
Length = 196
Score = 29.6 bits (65), Expect = 3.0
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Query: 12 LAGLAWSSASAPPPRGFSAISCTVEGAPAS 41
L L W +S PP G SCT+ G PAS
Sbjct: 78 LMALGWPPSSPSPPSG-DCCSCTIGGTPAS 106
>gi|239745486 PREDICTED: hypothetical protein XP_002343475 isoform 2
[Homo sapiens]
Length = 196
Score = 29.6 bits (65), Expect = 3.0
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Query: 12 LAGLAWSSASAPPPRGFSAISCTVEGAPAS 41
L L W +S PP G SCT+ G PAS
Sbjct: 78 LMALGWPPSSPSPPSG-DCCSCTIGGTPAS 106
>gi|239745484 PREDICTED: hypothetical protein XP_002343474 isoform 1
[Homo sapiens]
Length = 196
Score = 29.6 bits (65), Expect = 3.0
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Query: 12 LAGLAWSSASAPPPRGFSAISCTVEGAPAS 41
L L W +S PP G SCT+ G PAS
Sbjct: 78 LMALGWPPSSPSPPSG-DCCSCTIGGTPAS 106
>gi|24111244 MAM domain containing glycosylphosphatidylinositol
anchor 1 [Homo sapiens]
Length = 955
Score = 29.3 bits (64), Expect = 3.9
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 6/64 (9%)
Query: 7 TDSAPLAGLAWSSASAPPPRGFSAISCTVEGAPASFGKSFAQKSGYFLCLSSLGSLENPQ 66
T PL L WS P P G A +G S A+ SGY+ C ++ ++ NP
Sbjct: 265 TGGDPLPQLQWSHGPGPLPLGALA-----QGGTLSIPSVQARDSGYYNC-TATNNVGNPA 318
Query: 67 ENVV 70
+ V
Sbjct: 319 KKTV 322
>gi|7661990 mastermind-like 1 [Homo sapiens]
Length = 1016
Score = 28.9 bits (63), Expect = 5.0
Identities = 15/47 (31%), Positives = 23/47 (48%), Gaps = 3/47 (6%)
Query: 148 KKAKAPRPVPKPRGLSRDMQGLSLDAASQPSKGGLLERTASRLGSRA 194
++ AP P P P + + GLS + P G + AS++G RA
Sbjct: 910 QRTSAPAPAPPPTAPQQGLPGLS---PAGPELGAFSQSPASQMGGRA 953
>gi|46409512 hypothetical protein LOC400359 [Homo sapiens]
Length = 179
Score = 28.5 bits (62), Expect = 6.6
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Query: 38 APAS-FGKSFAQKSGYFLCLSSLGSLENPQENVVADIQIVVDKSPLPLGFSPV--CDPMD 94
APA F + + Q + + C++ S +P+ V +SPLP+ P C
Sbjct: 90 APAHVFRQCWVQGNAWISCITKFDSKRSPEVASSPSYLTVPRRSPLPVFLRPSDRCVCGG 149
Query: 95 SKASVSKKKRMCVKLL--PLGAT 115
S ++R C LL PLG T
Sbjct: 150 CYLGKSTRRRACQSLLSDPLGVT 172
>gi|239750588 PREDICTED: hypothetical protein XP_002347440 [Homo
sapiens]
Length = 510
Score = 28.5 bits (62), Expect = 6.6
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 3/46 (6%)
Query: 1 MDPVPGTDSAPLA---GLAWSSASAPPPRGFSAISCTVEGAPASFG 43
+ P PGT + LA G W + PP G + ++ +G PA G
Sbjct: 345 VSPPPGTGLSSLARPSGSGWLWPNVPPTCGNAGLAVVSQGVPAGAG 390
>gi|239744885 PREDICTED: hypothetical protein XP_002344275 [Homo
sapiens]
Length = 510
Score = 28.5 bits (62), Expect = 6.6
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 3/46 (6%)
Query: 1 MDPVPGTDSAPLA---GLAWSSASAPPPRGFSAISCTVEGAPASFG 43
+ P PGT + LA G W + PP G + ++ +G PA G
Sbjct: 345 VSPPPGTGLSSLARPSGSGWLWPNVPPTCGNAGLAVVSQGVPAGAG 390
>gi|226874831 guanylate kinase 1 isoform a [Homo sapiens]
Length = 218
Score = 28.5 bits (62), Expect = 6.6
Identities = 15/35 (42%), Positives = 18/35 (51%)
Query: 11 PLAGLAWSSASAPPPRGFSAISCTVEGAPASFGKS 45
PLAGLA ++ PP G S V P+ GKS
Sbjct: 5 PLAGLAAAALGRAPPDGMSGPRPVVLSGPSGAGKS 39
>gi|114145479 neuroepithelial cell transforming gene 1 isoform 1
[Homo sapiens]
Length = 596
Score = 28.1 bits (61), Expect = 8.6
Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 5/51 (9%)
Query: 152 APRPVPKPRGLSRDMQGLSLDAASQPSKGGLLERTASRLGSRASTLRRNDS 202
A + P+PR SR GLS + A+ PS + + S L R S LRR S
Sbjct: 6 AAQKQPRPRRRSRRASGLSTEGATGPS----ADTSGSELDGRCS-LRRGSS 51
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,623,669
Number of Sequences: 37866
Number of extensions: 555373
Number of successful extensions: 1690
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1681
Number of HSP's gapped (non-prelim): 21
length of query: 273
length of database: 18,247,518
effective HSP length: 101
effective length of query: 172
effective length of database: 14,423,052
effective search space: 2480764944
effective search space used: 2480764944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.