Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 24308169
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
(4116 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 8247 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 4036 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 3033 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 2551 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 2425 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 2012 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1938 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 1923 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1894 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1893 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 1869 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 1868 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 1868 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 1821 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1256 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1187 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 924 0.0
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 484 e-136
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 258 1e-67
gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens] 85 1e-15
gi|29294627 PTPRF interacting protein binding protein 1 isoform ... 45 0.001
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 42 0.010
gi|71061468 centromere protein E [Homo sapiens] 42 0.016
gi|24415404 MDN1, midasin homolog [Homo sapiens] 41 0.028
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 40 0.037
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 40 0.037
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 40 0.037
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 40 0.037
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 40 0.037
gi|55770834 centromere protein F [Homo sapiens] 40 0.048
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 8247 bits (21400), Expect = 0.0
Identities = 4116/4116 (100%), Positives = 4116/4116 (100%)
Query: 1 MGATGRLELTLAAPPHPGPAFQRSKARETQGEEEGSEMQIAKSDSIHHMSHSQGQPELPP 60
MGATGRLELTLAAPPHPGPAFQRSKARETQGEEEGSEMQIAKSDSIHHMSHSQGQPELPP
Sbjct: 1 MGATGRLELTLAAPPHPGPAFQRSKARETQGEEEGSEMQIAKSDSIHHMSHSQGQPELPP 60
Query: 61 LPASANEEPSGLYQTVMSHSFYPPLMQRTSWTLAAPFKEQHHHRGPSDSIANNYSLMAQD 120
LPASANEEPSGLYQTVMSHSFYPPLMQRTSWTLAAPFKEQHHHRGPSDSIANNYSLMAQD
Sbjct: 61 LPASANEEPSGLYQTVMSHSFYPPLMQRTSWTLAAPFKEQHHHRGPSDSIANNYSLMAQD 120
Query: 121 LKLKDLLKVYQPATISVPRDRTGQGLPSSGNRSSSEPMRKKTKFSSRNKEDSTRIKLAFK 180
LKLKDLLKVYQPATISVPRDRTGQGLPSSGNRSSSEPMRKKTKFSSRNKEDSTRIKLAFK
Sbjct: 121 LKLKDLLKVYQPATISVPRDRTGQGLPSSGNRSSSEPMRKKTKFSSRNKEDSTRIKLAFK 180
Query: 181 TSIFSPMKKEVKTSLTFPGSRPMSPEQQLDVMLQQEMEMESKEKKPSESDLERYYYYLTN 240
TSIFSPMKKEVKTSLTFPGSRPMSPEQQLDVMLQQEMEMESKEKKPSESDLERYYYYLTN
Sbjct: 181 TSIFSPMKKEVKTSLTFPGSRPMSPEQQLDVMLQQEMEMESKEKKPSESDLERYYYYLTN 240
Query: 241 GIRKDMIAPEEGEVMVRISKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKSIVDYIL 300
GIRKDMIAPEEGEVMVRISKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKSIVDYIL
Sbjct: 241 GIRKDMIAPEEGEVMVRISKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKSIVDYIL 300
Query: 301 MDPMERKRLFIESIPRLFPQRVIRAPVPWHSVYRSAKKWNEEHLHTVNPMMLRLKELWFA 360
MDPMERKRLFIESIPRLFPQRVIRAPVPWHSVYRSAKKWNEEHLHTVNPMMLRLKELWFA
Sbjct: 301 MDPMERKRLFIESIPRLFPQRVIRAPVPWHSVYRSAKKWNEEHLHTVNPMMLRLKELWFA 360
Query: 361 EFRDLRFVRTAEILAGKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLFTSRKEHWI 420
EFRDLRFVRTAEILAGKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLFTSRKEHWI
Sbjct: 361 EFRDLRFVRTAEILAGKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLFTSRKEHWI 420
Query: 421 HFAPKSNYDSSRNIEEYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGNDFKEPYQEM 480
HFAPKSNYDSSRNIEEYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGNDFKEPYQEM
Sbjct: 421 HFAPKSNYDSSRNIEEYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGNDFKEPYQEM 480
Query: 481 KFFIPQLIMIKLEVSEPIIVFNPSFDGCWELIRDSFLEIIKNSNGIPKLKYIPLKFSFTA 540
KFFIPQLIMIKLEVSEPIIVFNPSFDGCWELIRDSFLEIIKNSNGIPKLKYIPLKFSFTA
Sbjct: 481 KFFIPQLIMIKLEVSEPIIVFNPSFDGCWELIRDSFLEIIKNSNGIPKLKYIPLKFSFTA 540
Query: 541 AAADRQCVKAAEPGEPSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQTFKVFQKNQ 600
AAADRQCVKAAEPGEPSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQTFKVFQKNQ
Sbjct: 541 AAADRQCVKAAEPGEPSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQTFKVFQKNQ 600
Query: 601 VGPCKYLNVYKKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNITVP 660
VGPCKYLNVYKKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNITVP
Sbjct: 601 VGPCKYLNVYKKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNITVP 660
Query: 661 LAMFCLDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTK 720
LAMFCLDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTK
Sbjct: 661 LAMFCLDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTK 720
Query: 721 ELVSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDYADLPYQIEDIFDNSRNLLLHKRD 780
ELVSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDYADLPYQIEDIFDNSRNLLLHKRD
Sbjct: 721 ELVSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDYADLPYQIEDIFDNSRNLLLHKRD 780
Query: 781 QAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAEFE 840
QAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAEFE
Sbjct: 781 QAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAEFE 840
Query: 841 LINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIA 900
LINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIA
Sbjct: 841 LINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIA 900
Query: 901 EEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQI 960
EEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQI
Sbjct: 901 EEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQI 960
Query: 961 SEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTF 1020
SEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTF
Sbjct: 961 SEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTF 1020
Query: 1021 SFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNL 1080
SFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNL
Sbjct: 1021 SFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNL 1080
Query: 1081 DAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQP 1140
DAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQP
Sbjct: 1081 DAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQP 1140
Query: 1141 RMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLK 1200
RMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLK
Sbjct: 1141 RMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLK 1200
Query: 1201 KCFEGIAKLEFTDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMRE 1260
KCFEGIAKLEFTDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMRE
Sbjct: 1201 KCFEGIAKLEFTDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMRE 1260
Query: 1261 VIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALAENTLLDFLKKSNDQIAQ 1320
VIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALAENTLLDFLKKSNDQIAQ
Sbjct: 1261 VIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALAENTLLDFLKKSNDQIAQ 1320
Query: 1321 IVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDV 1380
IVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDV
Sbjct: 1321 IVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDV 1380
Query: 1381 QVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTK 1440
QVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTK
Sbjct: 1381 QVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTK 1440
Query: 1441 DLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILS 1500
DLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILS
Sbjct: 1441 DLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILS 1500
Query: 1501 IQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYA 1560
IQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYA
Sbjct: 1501 IQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYA 1560
Query: 1561 LIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKY 1620
LIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKY
Sbjct: 1561 LIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKY 1620
Query: 1621 PEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKK 1680
PEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKK
Sbjct: 1621 PEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKK 1680
Query: 1681 MKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFA 1740
MKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFA
Sbjct: 1681 MKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFA 1740
Query: 1741 VEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIW 1800
VEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIW
Sbjct: 1741 VEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIW 1800
Query: 1801 IENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGW 1860
IENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGW
Sbjct: 1801 IENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGW 1860
Query: 1861 KPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRL 1920
KPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRL
Sbjct: 1861 KPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRL 1920
Query: 1921 YSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFR 1980
YSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFR
Sbjct: 1921 YSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFR 1980
Query: 1981 NLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAG 2040
NLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAG
Sbjct: 1981 NLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAG 2040
Query: 2041 AKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNC 2100
AKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNC
Sbjct: 2041 AKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNC 2100
Query: 2101 INFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELL 2160
INFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELL
Sbjct: 2101 INFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELL 2160
Query: 2161 RQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDIL 2220
RQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDIL
Sbjct: 2161 RQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDIL 2220
Query: 2221 TKIFSSIVDWHFGKGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSR 2280
TKIFSSIVDWHFGKGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSR
Sbjct: 2221 TKIFSSIVDWHFGKGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSR 2280
Query: 2281 VIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTI 2340
VIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTI
Sbjct: 2281 VIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTI 2340
Query: 2341 EKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVMEHYLEEFNNIS 2400
EKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVMEHYLEEFNNIS
Sbjct: 2341 EKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVMEHYLEEFNNIS 2400
Query: 2401 KAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEI 2460
KAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEI
Sbjct: 2401 KAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEI 2460
Query: 2461 TKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPA 2520
TKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPA
Sbjct: 2461 TKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPA 2520
Query: 2521 DEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMF 2580
DEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMF
Sbjct: 2521 DEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMF 2580
Query: 2581 PSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEVVSMCKYFQESVKKLSLDYY 2640
PSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEVVSMCKYFQESVKKLSLDYY
Sbjct: 2581 PSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEVVSMCKYFQESVKKLSLDYY 2640
Query: 2641 NKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQREL 2700
NKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQREL
Sbjct: 2641 NKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQREL 2700
Query: 2701 TALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDL 2760
TALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDL
Sbjct: 2701 TALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDL 2760
Query: 2761 AEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSG 2820
AEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSG
Sbjct: 2761 AEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSG 2820
Query: 2821 KMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSA 2880
KMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSA
Sbjct: 2821 KMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSA 2880
Query: 2881 CEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALN 2940
CEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALN
Sbjct: 2881 CEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALN 2940
Query: 2941 DDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVL 3000
DDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVL
Sbjct: 2941 DDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVL 3000
Query: 3001 LSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLP 3060
LSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLP
Sbjct: 3001 LSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLP 3060
Query: 3061 VDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQ 3120
VDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQ
Sbjct: 3061 VDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQ 3120
Query: 3121 LGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPH 3180
LGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPH
Sbjct: 3121 LGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPH 3180
Query: 3181 YLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIED 3240
YLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIED
Sbjct: 3181 YLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIED 3240
Query: 3241 KILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVH 3300
KILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVH
Sbjct: 3241 KILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVH 3300
Query: 3301 SATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNN 3360
SATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNN
Sbjct: 3301 SATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNN 3360
Query: 3361 VCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPYPNPAPQWLSEKAW 3420
VCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPYPNPAPQWLSEKAW
Sbjct: 3361 VCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPYPNPAPQWLSEKAW 3420
Query: 3421 AEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLR 3480
AEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLR
Sbjct: 3421 AEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLR 3480
Query: 3481 PDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFAD 3540
PDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFAD
Sbjct: 3481 PDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFAD 3540
Query: 3541 DLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIV 3600
DLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIV
Sbjct: 3541 DLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIV 3600
Query: 3601 PESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQS 3660
PESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQS
Sbjct: 3601 PESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQS 3660
Query: 3661 CAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEV 3720
CAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEV
Sbjct: 3661 CAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEV 3720
Query: 3721 PFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSY 3780
PFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSY
Sbjct: 3721 PFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSY 3780
Query: 3781 QSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVV 3840
QSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVV
Sbjct: 3781 QSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVV 3840
Query: 3841 EELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRA 3900
EELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRA
Sbjct: 3841 EELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRA 3900
Query: 3901 IKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGP 3960
IKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGP
Sbjct: 3901 IKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGP 3960
Query: 3961 PVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQETVMENNPEDGAYIKGL 4020
PVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQETVMENNPEDGAYIKGL
Sbjct: 3961 PVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQETVMENNPEDGAYIKGL 4020
Query: 4021 FLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLS 4080
FLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLS
Sbjct: 4021 FLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLS 4080
Query: 4081 TTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLDN 4116
TTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLDN
Sbjct: 4081 TTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLDN 4116
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 4036 bits (10466), Expect = 0.0
Identities = 2071/3957 (52%), Positives = 2724/3957 (68%), Gaps = 110/3957 (2%)
Query: 209 LDVMLQQEMEMESKEK------KPS----ESDLERYYYYLTNGIRKDMIAPEEGEVMVRI 258
++V++QQ+ +++S KP+ E D+ RYYYY+ +GI D +AP E + +
Sbjct: 129 VNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPMEDSWLEHV 188
Query: 259 SKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKSIVDYILMDPMER---KRLFIESIP 315
L+ L +V L E DY S+ KSIVD++L DP E+ K+ + +P
Sbjct: 189 LDLVPQHLKV---FTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKT--DELP 243
Query: 316 RLFPQRVIRAPVPWHSVYRSAKKWNEEHLHTVNPMMLRLKELWFAEFRDLRFVRTAEILA 375
+ I P PW + +A + +HL+ +NP ML + +LW F+ LR V E
Sbjct: 244 AHRAEMEI-LPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEFHN 302
Query: 376 GKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLFTSRKEHWIHFAPKSNYDSSRNIE 435
+ L+ F ++I +H A +TLL W P ++ + DSS +E
Sbjct: 303 CQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKK----KQLPTGDSSAKLE 358
Query: 436 EYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGNDFKEPYQEMKFFIPQLIMIKLEVS 495
+F A+ M+LQL++L + S++D L +P ++ F +++L +
Sbjct: 359 SFFNCAAALMTLQLQDLTLVSMQDFTDL---------IAQPPDSVRAFEHPGFIMRLILD 409
Query: 496 EPIIVFNPSFDGCWELIRDSFLEIIKNSNGIPKLKYIPLKFSFTAAAADRQCVKAAEPGE 555
I F P ++ + + +IK + +P+++ + K +
Sbjct: 410 NDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVE-------------TKLYSKWESKSK 456
Query: 556 PSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQTFKVFQKNQVGPCKYLNVYKKYVD 615
P T + + +L V+A ++ + + V K V P ++L +Y KY
Sbjct: 457 P------TTLKPI----ILNEIVDAHKEKIKE-------VIMKESVAPTEHLRLYDKYDF 499
Query: 616 LLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNI-TVPLAMFCLDATALNHD 674
L+ AE+++ FL ENH + + +I +K EI +I T+ L MF + L
Sbjct: 500 LITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRA 559
Query: 675 LCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSLIEFLKKSSA 734
L +RA + L+ +++ NT +C+++ IA+K P NT EL+ + +++K
Sbjct: 560 LVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEV 619
Query: 735 VTVFKLRRQLRDASERLEFLMDY-----ADLPY---------QIEDIFDNSRNLLLHKRD 780
+ +L ++L D+ L FL++Y AD+ ++ +IF+ R ++ K +
Sbjct: 620 TDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIE 679
Query: 781 QAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAEFE 840
Q + L RC F LE Y ++ E F ++++ ++K L+ L+ A + E
Sbjct: 680 QYQEGLKLRCERFVEELESYAKQSEEF--YSFGDLQDVQRYLKKAQILNGKLDLAADKIE 737
Query: 841 LINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIA 900
N EEE S YP + + PY +L+ TA EFS W GP +N +Q+
Sbjct: 738 QFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVE 797
Query: 901 EEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQI 960
+IGN WR YKL KT D P + + V+ K++ FKQ+IP++ + CNPG++ RHW+ +
Sbjct: 798 ADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAM 857
Query: 961 SEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTF 1020
S IVGY ++P++ + +S+ L+ ++++ E I AASKEYSLEK +++M +W V F
Sbjct: 858 SAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEF 917
Query: 1021 SFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNL 1080
YR+T T IL ++D+IQMLLDDH+IKTQTM GSPFIKP E + R+WE KL+ +Q+ L
Sbjct: 918 VIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEIL 977
Query: 1081 DAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQP 1140
D WLK QATWLYLEPIFSS DI++QMPEEGR+F VD W+ +M ++D +L
Sbjct: 978 DEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTID 1037
Query: 1141 RMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLK 1200
RM E+L+++N LLE I KGLN+YLEKKRLFFPRFFFLSNDELLEILSETKDP RVQPHLK
Sbjct: 1038 RMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLK 1097
Query: 1201 KCFEGIAKLEFTDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMRE 1260
KCFEGIAK+EFT+ L+I M SSE E V I+ I A A+G VEKWL ++E++M+ S+ +
Sbjct: 1098 KCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHK 1157
Query: 1261 VIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQA--LAENTLLDFLKKSNDQI 1318
V G AY K R +WV WPGQ V+CVS IFWT+EV A + L +LK N QI
Sbjct: 1158 VTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQI 1217
Query: 1319 AQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAK 1378
IV LVRGKLS R+TLGAL V+DVHARDV++ L + +SD +DF+W+SQLRYYW
Sbjct: 1218 DDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQEN 1277
Query: 1379 DVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTET 1438
++ ++I YGYEYLGNSPRLVITPLTDRCYRTL GAL L+LGGAPEGPAGTGKTET
Sbjct: 1278 HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTET 1337
Query: 1439 TKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQI 1498
TKDLAKA+AKQCVVFNCSDGLDY A+GKFFKGL GAWACFDEFNRI++EVLSVVAQQI
Sbjct: 1338 TKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQI 1397
Query: 1499 LSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPD 1558
L+IQ+ I +FEGTEL L+PTCAVFITMNPGYAGR+ELPDNLKALFRTVAMMVPD
Sbjct: 1398 LTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPD 1457
Query: 1559 YALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL 1618
YA+I EI LYS GF+ +R L+ KIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL
Sbjct: 1458 YAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL 1517
Query: 1619 KYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNI 1678
KYP ENE +LLLR+++DVNL KFL+ D+PLF+GI SDLFPGV LPKPDY L + DN
Sbjct: 1518 KYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNC 1577
Query: 1679 KKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEE 1738
M LQ +F KI+Q+YEMM+VRHG+MIVG+P GGKTSAY+VLA AL D+ MEE
Sbjct: 1578 ASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEE 1637
Query: 1739 FAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDA 1798
V+ ++NPK++TMGQLYG FD VSHEW DGVLA +FR ASS++ DRKW+IFDGPVDA
Sbjct: 1638 NKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDA 1697
Query: 1799 IWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQL 1858
+WIENMNTVLDDNKKLCLMSGEIIQM+ +M+LIFEP DLE ASPATVSRCGMIYMEPH L
Sbjct: 1698 VWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHML 1757
Query: 1859 GWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMM 1918
GW+PL S+++ LP+S++ KE + +F +V +EF R H K + TS +L S+M
Sbjct: 1758 GWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLM 1817
Query: 1919 RLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVF 1978
L +D+ +E++L E + ++ + L+G+FLFSL+W+V + D R KF+
Sbjct: 1818 NLIDCFMDDF----ADEVKLKE-RNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKI 1872
Query: 1979 FRNLIMGMDDNHPRPKSVKLTKNN----------IFPERGSIYDFYFIKQASGHWETWTQ 2028
R L+ + R + KL FPE+G+IYD+ F+ + G WE W +
Sbjct: 1873 LRELMESPISDRTR-NTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIK 1931
Query: 2029 YITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFL 2088
+ KE +P +E+I+PT++T R S ++ H+ P +FVGPTGTGKS NFL
Sbjct: 1932 KL-KEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFL 1990
Query: 2089 LH-LPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPA 2147
L+ L K Y P INFSA+T+A QTQ+I+MSKLD+RRKG+FGPP+GK+ VVFVDD+NMPA
Sbjct: 1991 LNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPA 2050
Query: 2148 KEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHL 2207
+EVYGAQPPIELLRQW+DH W+D KD + + +VD+ ++ AMGPPGGGRN +T R+ RH
Sbjct: 2051 REVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHF 2110
Query: 2208 NIISINAFEDDILTKIFSSIVDWHFG--KGFDVMFLRYGKMLVQATKTIYRDAVENFLPT 2265
NII+IN F D + IFS I+ WH F FL +V T T+Y++A++N LPT
Sbjct: 2111 NIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPT 2170
Query: 2266 PSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFF 2325
P+KSHY+FNLRDFSRVIQGV L + E RLW+HEV RV+YDRL+D DR
Sbjct: 2171 PAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLI 2230
Query: 2326 NMVKETTSNCFKQTIEKVL--IHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLK 2383
N ++E N + ++ + G + D++RSL F D+ P+ + Y EI D+
Sbjct: 2231 NYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIADVD 2290
Query: 2384 QLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSA 2443
L +++E +LEE+NNISK PM+LV+FRFAIEHISRI R+LKQ + H LLVG+GGSGRQS
Sbjct: 2291 NLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSV 2350
Query: 2444 AKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVE 2503
+L+ M Y ++Q+EI+K Y +W EDLK I+ + VFLF D QIK+ESF+E
Sbjct: 2351 TRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLE 2410
Query: 2504 DINMLLNTGDVPNIFPADEKADIVEKMQ--TAARTQGEKVEVTPLSMYNFFIERVINKIS 2561
D++ LLN G++PN+F DEK +I +KM+ R + ++ + +P++++N FI+ +++
Sbjct: 2411 DVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLH 2470
Query: 2562 FSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEV 2621
LAMSPIGDAFRNRLR FP+L+NCCTIDWFQSWP DAL+ VA++FLE++E+ + IR
Sbjct: 2471 VVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGC 2530
Query: 2622 VSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLT 2681
+ MCK F S LS ++ +L+R+NYVTPTSYLELI TFK LL KR EV M+ RY
Sbjct: 2531 IDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEV 2590
Query: 2682 GLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKE 2741
GL+KLD A+SQVA MQ EL AL PQL + S+E +MM+ IE E+ E + +V+ADE
Sbjct: 2591 GLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETI 2650
Query: 2742 ANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMES 2801
AN A ++ IK+EC+ DLA A+P LE+ALAALDTL DI++VKSM++PP VKLVME+
Sbjct: 2651 ANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEA 2710
Query: 2802 ICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRE 2861
ICI+KG+K ++ PDP+GSGK IED+WG +K++LGD++FL+SL YDKDNIPP M IR+
Sbjct: 2711 ICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRK 2770
Query: 2862 RFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQK 2921
+I +P+F P I+N S+A EGLCKWV AM+ YD+VAK+VAPK+ +L AEG+L M
Sbjct: 2771 NYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDG 2830
Query: 2922 LNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRW 2981
L +K+A LK V D+L L D E KK DLE +++CS+KL RAE+LI GLGGEK RW
Sbjct: 2831 LRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRW 2890
Query: 2982 TEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSL 3041
+ A +LG Y NLTGD+L+SSG VAYLGAFT YR +W CK + IP D SL
Sbjct: 2891 SHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSDDCSL 2950
Query: 3042 SHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKL 3101
TLG+ + IR W IAGLP DSFSIDNGII+ N+RRW LMIDP QANKWIKNMEKAN L
Sbjct: 2951 MGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSL 3010
Query: 3102 AVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENI 3161
VIK S+ +Y+R LEN +Q GTPVL+EN+GEELD +EP+LLK TFKQ G +RLG++
Sbjct: 3011 YVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDST 3070
Query: 3162 IEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKK 3221
IEY+ DF+ YITT+LRNPHYLPE +VKV LLNFMITP G+QDQLLGIV A+E+P+LEE+K
Sbjct: 3071 IEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEK 3130
Query: 3222 NQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVAS 3281
LI++ A+NK+ LKEIEDKILEVLS S+GNILEDETAIK+LSSSK L+ EIS+KQ+VA
Sbjct: 3131 QALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAE 3190
Query: 3282 MTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEE 3341
TE +ID TRMGY+P+A+HS+ +FF ++DLANIEPMYQYSLTWFINL++ S+ +S KSE
Sbjct: 3191 ETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEI 3250
Query: 3342 LNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGI 3401
L R++ + DHFT S+Y NVCRSLFEKDKLLFS LTI ++ ++ I + W FLLTGGI
Sbjct: 3251 LAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGI 3310
Query: 3402 ALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLP 3461
LDNPY N WL +K+W EI R LP + + WK +YDS PH E P
Sbjct: 3311 GLDNPYANLC-TWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVFP 3369
Query: 3462 GSWK-FSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAP 3520
W+ + ++M+I+RCLRPDK++P ++EFI +G+ +IE P FDL ++ DS+CCAP
Sbjct: 3370 EEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAP 3429
Query: 3521 LIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQN 3580
LIFVLSP ADPMA LLKFADD G GG++ ++SLGQGQGPIA KM+ A+K+GTWVVLQN
Sbjct: 3430 LIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQN 3489
Query: 3581 CHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLR 3640
CHLA SWMPTLEK+CEE + PEST+ FR+WLTSYPS FPVS+LQNG+KMTNE PKGLR
Sbjct: 3490 CHLATSWMPTLEKVCEE-LSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLR 3548
Query: 3641 ANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNE 3700
AN++RSYL DPISDP FF SC K ++K+L+GLCFFHA+VQERR FGPLGWNIPYEFNE
Sbjct: 3549 ANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNE 3608
Query: 3701 SDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKE-I 3759
+DLRIS+ Q+ MFLN Y+E+P++AL Y+TGECNYGGRVTDD DRR L S+L+ F+ E +
Sbjct: 3609 TDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELV 3668
Query: 3760 EEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFE 3819
E Y Y++PP G ++SYI+Y + LP+T PE+FG++ NADITKD ET LF+
Sbjct: 3669 ENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFD 3728
Query: 3820 GVLLTLPRQSGGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQE 3879
+LLT R +G KS EVV E+A DIL KLP +FD+E M+ YP Y +SMNTVL QE
Sbjct: 3729 NILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQE 3788
Query: 3880 LIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLG 3939
+ RFN+L K +R S +N+ +AIKG +MS++LEEV +S+L K+P MW KSYPSLKPLG
Sbjct: 3789 MGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLG 3848
Query: 3940 GYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFE 3999
YV D LARL F Q+W + GPP VFW+SGF+FTQ+FLTG QNYARKYTIPID +GF++E
Sbjct: 3849 SYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYE 3908
Query: 4000 VTPQETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMF 4059
V ++ ++ PEDG +I GLFL+GA W+RK ++ ES PKILYD +P++WLKP + A
Sbjct: 3909 VM-EDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADI 3967
Query: 4060 LHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLDN 4116
+ YV P+YKTS RRG LSTTGHSTN+V+++ LP+D P++HWI RGVA LCQL++
Sbjct: 3968 PKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQLNS 4024
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 3033 bits (7863), Expect = 0.0
Identities = 1620/3612 (44%), Positives = 2286/3612 (63%), Gaps = 132/3612 (3%)
Query: 574 LLGTVNAEEKLVSDFLIQTFKVFQKNQVGPCKYLNVYKKYVDLLDNTAEQNIAAFLKENH 633
LL +V E LV + K + Y Y+KY++L +N +IA+FLK
Sbjct: 715 LLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNN----DIASFLKTYQ 770
Query: 634 D---IDDFVTKINAIKKRRNEI--ASMNITVPLAMFCLDATALNHDLCERAQNLKDHLIQ 688
+ V ++ R EI +S+ ++ + F ++ + L ++ + L ++
Sbjct: 771 TQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLD 830
Query: 689 FQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSLIEFLKKSSAVTVFKLRRQLRDAS 748
SIC ++ I+ K+ E P + +EL L E++K + +L
Sbjct: 831 ILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKG--------IPERLVGLE 882
Query: 749 ERLEFLMDYADLPYQIEDIF-DNSRNLLLHKRDQAEMDLIKRCSEFELRLEGYHRELESF 807
ER+ +MD YQ+ D F N + + + A K + EL + + + E F
Sbjct: 883 ERIVKVMD----DYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKF 938
Query: 808 RKREVMTTEEMKHNVEKL----------------NELSKNLNRAFAEFE-------LINK 844
RK ++M + +E L +E++ + R + + L N
Sbjct: 939 RKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNN 998
Query: 845 EEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEEIG 904
E + + Y L M+K PY LW+TA ++ SE WMN PL ++AEQ+ + +
Sbjct: 999 RERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVV 1058
Query: 905 NMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISEIV 964
++T +K +K D+PA + +A +++ +I++FK YIP++ NPGM+ RHW+ +S +
Sbjct: 1059 EAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQI 1118
Query: 965 GYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVK 1024
++P + LE +E + + A KEY++E+ LD+M+ +W + F+ +
Sbjct: 1119 NINVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLP 1178
Query: 1025 YRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWL 1084
Y+ TDT IL + D+ LLDDH++ TQ M SP+ KP E WE KL Q+ L+ WL
Sbjct: 1179 YKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWL 1238
Query: 1085 KCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPRMAE 1144
CQ +WLYLEPIFSSEDI Q+P E +++ ++ WK +M A ++ ++ RM +
Sbjct: 1239 NCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLD 1298
Query: 1145 KLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKKCFE 1204
L++ N +L+ +QKGL++YLE KR FPRF+FLS+DELLEILS+TKDP VQPHL+KCFE
Sbjct: 1299 SLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFE 1358
Query: 1205 GIAKLEFTDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGL 1264
IA+L F ++LEI M S+E E V IYP++ VE WL++VE+ M AS+ ++I
Sbjct: 1359 NIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSN---VEDWLREVERSMKASVHDIIEK 1415
Query: 1265 GIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQAL-AENTLLDFLKKSNDQIAQIVQ 1323
I AY +PR WVL WPGQV I +WT EV++AL A N + Q++ +V
Sbjct: 1416 AIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVA 1475
Query: 1324 LVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDVQVQ 1383
LVRGKLS R L AL VI+VHA+DVV+KL ++ V +NDFQWISQLRYYW D+ ++
Sbjct: 1476 LVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIR 1535
Query: 1384 IITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLA 1443
+ E +YGYEYLGNS RLVITPLTDRCY TL GAL L GGAP GPAGTGKTETTKDL
Sbjct: 1536 AVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLG 1595
Query: 1444 KALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQ 1503
KALA Q VVFNCSD LD+ AMGKFFKGLA AGAWACFDEFNRI++EVLSVVAQQI +IQ+
Sbjct: 1596 KALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQK 1655
Query: 1504 AIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIG 1563
A ++++ F+FEG E+ L P+CAVFITMNPGYAGR ELPDNLKALFR VAMMVPDYA+I
Sbjct: 1656 AQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMIT 1715
Query: 1564 EISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEE 1623
EISLYS GF ++ LA+KI T++L SEQLSSQ HYD+GMRAVK+V++AAGNLK + P
Sbjct: 1716 EISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSM 1775
Query: 1624 NESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKL 1683
NE ++ LRA+ DVN+ KFL +D+ LF GI+SDLFP + DY + + + + + L
Sbjct: 1776 NEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNL 1835
Query: 1684 QPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHA----ANQMEEF 1739
+ V F+ K IQ+YE +VRHG M+VG GK++ Y+VLAAA+ L + M E
Sbjct: 1836 KDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYE- 1894
Query: 1740 AVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAI 1799
AV Y ++NPK+ITMGQLYG FD ++HEW DG+ ++ R A + ++KW +FDGPVDAI
Sbjct: 1895 AVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAI 1954
Query: 1800 WIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLG 1859
WIENMNTVLDDNKKLCL SGEII++ M+++FE DL ASPATVSRCGM+Y+EP LG
Sbjct: 1955 WIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILG 2014
Query: 1860 WKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMR 1919
P + ++ LP L K ++E +F+ ++ + F R K V+ ++ +L S+++
Sbjct: 2015 LMPFIECWLRKLPP-LLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLK 2073
Query: 1920 LYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFF 1979
L E + E LS +I ++ F+FSL+W+V T ++ R F +
Sbjct: 2074 LLDCFFKPFLPREGLKKIPSEKLS--RIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWL 2131
Query: 1980 RNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPA 2039
R + ++ +LT +FPE G ++D+ + +G T +EE K A
Sbjct: 2132 RL----------KMENEQLTL--LFPEEGLVFDYRL--EDAGISGTNDSEDEEEEYKQVA 2177
Query: 2040 GAKVSE---------------LIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAIT 2084
K + +I+PTM+T + S L L ++ P+L +GPTGTGK+
Sbjct: 2178 WVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTI 2237
Query: 2085 NNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLN 2144
++ LL Y+ + + FSARTSANQTQD I SKLD+RRKG+FGPP+G+ + F+DDLN
Sbjct: 2238 SDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLN 2297
Query: 2145 MPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRL-DIVDMLLVTAMGPPGGGRNDITGRF 2203
MPA E YGAQPPIELLRQW+DHG W+D+K ++VD+ V AMGPPGGGRN +T R
Sbjct: 2298 MPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRL 2357
Query: 2204 TRHLNIISINAFEDDILTKIFSSIV-DWHFGKGFDVMF----------LRYGKMLVQATK 2252
RH N +S ++ +IFS+I+ +W G + + + + LV+AT
Sbjct: 2358 MRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATI 2417
Query: 2253 TIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFY 2312
+Y LPTP+KSHY FNLRD S+V QG+L+ ++D + +RLW HE RVF
Sbjct: 2418 MVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFR 2477
Query: 2313 DRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESD 2372
DRL+++EDR F ++K ++ T KV + + +GD+ P SD
Sbjct: 2478 DRLVNEEDRSWFDQLLKRCMEQ-WEVTFNKVC------------PFQPILYGDFMSPGSD 2524
Query: 2373 QKIYDEITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLL 2432
K Y+ IT ++ V+E Y+E++N I+ A + LV+F A+ HI RI R L+Q G+ LL
Sbjct: 2525 VKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALL 2584
Query: 2433 VGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFA 2492
+G+GGSGR S +L++ M YE +QIE++KNY ++WR+D+KK++L+ G+ FLF+
Sbjct: 2585 LGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFS 2644
Query: 2493 DNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFF 2552
D QIK+ESF+EDIN +LN+GD+PN++ ADE+ IV M+ + QG ++ T ++ +
Sbjct: 2645 DTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQG--LQPTKANLMAAY 2702
Query: 2553 IERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVE 2612
RV + I L MSPIG+ FR RLR FPSL+NCCTIDWF WP +AL+ VA FL ++
Sbjct: 2703 TGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIP 2762
Query: 2613 LDDNIRVEV---VSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKR 2669
++ + E+ + +C Y +SV K ++Y +L RHNYVTP SYLEL+ F L+ K+
Sbjct: 2763 ELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKK 2822
Query: 2670 QEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREAD 2729
E+ +NR +GL KL + VA MQ +L ++ P L +++T M +I+ +T A+
Sbjct: 2823 LELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAE 2882
Query: 2730 GKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQ 2789
+ VQ +E +AN A AQ I ++ + DL EA+PAL+AALA+L LN D++ V++MQ
Sbjct: 2883 ETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQ 2942
Query: 2790 NPPGPVKLVMESICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDL-KFLESLKTYDK 2848
PP VKLV+E++CIMKG+KP++ P G ++DYW K +L D FLESL +DK
Sbjct: 2943 RPPPGVKLVIEAVCIMKGIKPKKVPGEK-PGTKVDDYWEPGKGLLQDPGHFLESLFKFDK 3001
Query: 2849 DNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERL 2908
DNI + +K I+ +I++ EFQPA I VS AC +C+WVRAM Y VAK V PKR+ L
Sbjct: 3002 DNIGDVVIKAIQP-YIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQAL 3060
Query: 2909 REAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAE 2968
EA+ L + L++ + L+ V D + + + E TKK++LE E C Q+L RA
Sbjct: 3061 LEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAG 3120
Query: 2969 KLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAEC 3028
KLI+GL EK RW E L N++GDVL+++G VAYLG FT YR + W+ +
Sbjct: 3121 KLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL 3180
Query: 3029 KDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQA 3088
+ +P S+ +L TLG+P+KIR+WQIAGLP D+ S++NG+I S+RW IDP QA
Sbjct: 3181 RSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQA 3240
Query: 3089 NKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFK 3148
NKWIKNMEK N L V K SD +++R +ENA++ G P L+EN+GEELD ++EP+LLK T+K
Sbjct: 3241 NKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYK 3300
Query: 3149 QQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGI 3208
QQG ++LG+ +I Y DF++YITT+L NPHY PE++ K+ L+NF ++P GL+DQLLG
Sbjct: 3301 QQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQ 3360
Query: 3209 VAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKV 3268
V A+E+P+LEE KNQLI+ +AK ++ LK+IED+IL LS S+GN ++D IKVL +SK+
Sbjct: 3361 VVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKM 3420
Query: 3269 LSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINL 3328
+ EI K ++A TE ID TRM Y PVA+ + +FFC+SDLAN++PMYQYSL WF+N+
Sbjct: 3421 KAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNI 3480
Query: 3329 YMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEI 3388
++ + +S +++ L RI I + T S+Y+NVCRSLFEK KL+F+ LL + IM + +I
Sbjct: 3481 FLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKI 3540
Query: 3389 TEEVWYFLLTGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKL 3448
+ W +LL+GG ++ NPAP WLS++AW +I+ S LP ++L E+++
Sbjct: 3541 NQSEWRYLLSGG-SISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRV 3599
Query: 3449 IYDSAWPHEEQLPGSW-KFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFD 3507
I+DS PH E LPG W ++ +K+++LRCLR DK+ A+++F+A ++ +IE T +
Sbjct: 3600 IFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTAN 3659
Query: 3508 LQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMIN 3567
L + DS+ PLIFVLSP DP A L KFA+++ + ISLGQGQGP A M+
Sbjct: 3660 LSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAISLGQGQGPRAEAMMR 3718
Query: 3568 NAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQN 3627
++I+ G WV QNCHLA SWMP LE++ E I P+ + FRLWLTS PS KFPVSILQN
Sbjct: 3719 SSIERGKWVFFQNCHLAPSWMPALERLIEH-INPDKVHRDFRLWLTSLPSNKFPVSILQN 3777
Query: 3628 GIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNF 3687
G KMT EPP+G+RANLL+SY + F SC K + ++ +L LC FH ERR F
Sbjct: 3778 GSKMTIEPPRGVRANLLKSYSS---LGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKF 3834
Query: 3688 GPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLL 3747
GPLG+NIPYEF + DLRI + Q++MFL++Y ++P+ L Y GE NYGGRVTDD DRR +
Sbjct: 3835 GPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCI 3894
Query: 3748 LSLLSMFYCKEIEEDYYSLAPGDTYY-IPPHGSYQSYIDYLRNLPITAHPEVFGLHENAD 3806
+++L FY ++ +S + Y+ IPP Y+ Y+++LP+ PE+FGLH+NA+
Sbjct: 3895 MNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNAN 3954
Query: 3807 ITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPV 3866
IT ET L ++ P+ S + +E+VE++ Q+IL K+P +L+ VM YPV
Sbjct: 3955 ITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPV 4014
Query: 3867 VYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAM 3926
+YEESMNTVL QE+IR+NRL +V+ ++L +L +A+KG V+MSS+LE + S+ VP +
Sbjct: 4015 LYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPEL 4074
Query: 3927 WAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARK 3986
W+AK+YPSLKPL +V DLL RL F Q WI G P VFWISGF+F Q+FLTG QN+ARK
Sbjct: 4075 WSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARK 4134
Query: 3987 YTIPIDHIGFEFEV---TPQETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILY 4043
+ I ID I F+F+V P E + P+ G YI GLFLEGARWD + Q+ ES PK LY
Sbjct: 4135 FVISIDTISFDFKVMFEAPSE--LTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELY 4192
Query: 4044 DPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHW 4103
+ +IWL P + QD Y+CP+YKT R GTLSTTGHSTNYV+++E+PT PQ+HW
Sbjct: 4193 TEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHW 4252
Query: 4104 INRGVASLCQLD 4115
I RGVA +C LD
Sbjct: 4253 IKRGVALICALD 4264
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 2551 bits (6613), Expect = 0.0
Identities = 1430/3621 (39%), Positives = 2127/3621 (58%), Gaps = 190/3621 (5%)
Query: 606 YLNVYKKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNITVPLAMFC 665
Y ++K+ ++ A + DI+ F ++ K+ + ++ T + +
Sbjct: 614 YAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLL 673
Query: 666 LDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSL 725
+D L L + L ++ +I + K+ VP T E V
Sbjct: 674 IDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHS 733
Query: 726 IEFLKK------------SSAVTVFKLRRQLRDASERLEFLMDYADLPYQIEDIFDNSRN 773
+ FL + + ++KL Q + + +F + +A + I + RN
Sbjct: 734 LLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAV-FATMKPSIVAV----RN 788
Query: 774 LLLHKRDQAEMDLIKRCSEFELRLEGYHRELESFR-KREVMTTEEMKHNVEKLNELSKNL 832
+ E + + C LE + E+ + + + ++ + +K+ + NL
Sbjct: 789 AIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNNL 848
Query: 833 NRAFAEFELINKEEELLEK----EKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMN 888
A+ + + + +K E S + L+ + + LW + E+ +EW+
Sbjct: 849 QSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLK 908
Query: 889 GPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISC 948
L+ E + ++ + +L K L P + +K K++K K+ +P++
Sbjct: 909 SKFDCLDPEVLNGQVSKYAKFVTQLEKGLP----PNSVVPQLKYKVEKMKEKLPVIIDLR 964
Query: 949 NPGMKDRHWQQISEIVGYEIKPTETTC----LSNMLEFGFGKFVEKLEPIGAAASKEYSL 1004
NP +K RHW I + V + E LS + F FG ++++ I AS E +L
Sbjct: 965 NPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFG---QEIQDISGQASGEAAL 1021
Query: 1005 EKNLDRMKLDWVNVTFSFVKYRDT-DTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIE 1063
E L +++ W F + +RD+ D IL DDIQ+LLDD I T+ S ++ P++
Sbjct: 1022 EAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLK 1081
Query: 1064 AECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSL 1123
+W+++L L+ WL CQ WLYLE IF++ DI Q+P E + F VD WK +
Sbjct: 1082 TRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEI 1141
Query: 1124 MSQAVKDNRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELL 1183
M + + L AA QP + E Q N LL+ IQK L YLE KR+ FPRF+FLSNDELL
Sbjct: 1142 MRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELL 1201
Query: 1184 EILSETKDPLRVQPHLKKCFEGIAKLEFT-------------------DNLEIVGMISSE 1224
EIL++T++P VQPHL+KCF+ I+KLEF +I+ M+S E
Sbjct: 1202 EILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPE 1261
Query: 1225 KETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRNHWVLQW-PG 1283
E V + + A+G VE+WL +VE+ M S+R + I Y R WV+ P
Sbjct: 1262 GERVSLGKGL---KARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPS 1318
Query: 1284 QVVICVSSIFWTQEVSQALAEN------TLLDFLKKSNDQIAQIVQLVRGKLSSGARLTL 1337
QV++ VS I W +++++ L L +F K + +++ + +V+G L R L
Sbjct: 1319 QVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNIL 1378
Query: 1338 GALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAK--DVQVQIITTEALYGYEY 1395
AL IDVHARD+V +L + +V + F W QLRYYW + ++ ++ YGYEY
Sbjct: 1379 TALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEY 1438
Query: 1396 LGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNC 1455
LG PRLVITPLTDRCY LMGAL+L+LGGAP GPAGTGKTETTKDLAKALA QCVVFNC
Sbjct: 1439 LGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNC 1498
Query: 1456 SDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFE 1515
SDGLDYK MG+FF GLAQ+GAW CFDEFNRI++EVLSV+AQQ+++I+ A KL F+FE
Sbjct: 1499 SDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFE 1558
Query: 1516 GTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDS 1575
G E+ L TCA FITMNPGYAGR ELPDNLKALFR AMMVP+YALI E+ LYS GF S
Sbjct: 1559 GREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESS 1618
Query: 1576 RSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLD 1635
+ LA+K+ Y+LCSEQLS Q HYD+GMRAVKSVL AG+LK + P+ NE V+L+RAL D
Sbjct: 1619 KILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQD 1678
Query: 1636 VNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQ 1695
NL KFL D LF GIISDLFPGV +P+ DY + + D + + LQP + K+IQ
Sbjct: 1679 SNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQ 1738
Query: 1696 IYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEF--AVEYKIINPKAITM 1753
YE MLVRHG M+VG GGKT+ Y++LA LG+L F AV+ ++NPK+ITM
Sbjct: 1739 FYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITM 1798
Query: 1754 GQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKK 1813
G+LYG + ++ EW DG++A + R + S+D KWII DGPVDA+WIENMNTVLDDNK
Sbjct: 1799 GELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKM 1858
Query: 1814 LCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPS 1873
LCL + E I++ ++ ++FE DL ASPATVSRCGM++++P +L W P ++M +
Sbjct: 1859 LCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISK 1918
Query: 1874 SLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEE 1933
LT+E +E + ++F V L F C + I ++ L SL+ + +
Sbjct: 1919 KLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLI-----LGK 1973
Query: 1934 EEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRP 1993
+ + L + ++ L F+F +W++ G + + FD F R D++P
Sbjct: 1974 DGVNLA--MEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQF----DDNPDA 2027
Query: 1994 KSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYIT--KEEEKVPAGAKVSELIIPTM 2051
+ P G ++ + + W + I K VP E+++PT
Sbjct: 2028 R---------LPNSGDLWSIHMDFDTK-RLDPWERIIPTFKYNRDVP----FFEMLVPTT 2073
Query: 2052 ETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNT-YLPNCINFSARTSAN 2110
+T R + ++ L + +LF G TG GKS I L + ++ Y+P +NFSA+TS+
Sbjct: 2074 DTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSA 2133
Query: 2111 QTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWF 2170
+TQ+II SKL+R+RK + G P K+ V+FVDDLNMP + YG+QPPIELLRQ+ D G ++
Sbjct: 2134 RTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFY 2193
Query: 2171 DKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDW 2230
D+ +I D+ +++A PPGGGRN +T RF RH +++ + + L +IF +I++
Sbjct: 2194 DRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNG 2253
Query: 2231 HFGKGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPH 2290
F F + +V+A+ IY + LPTP+KSHYVFNLRD S+ +QG+L C
Sbjct: 2254 -FLSDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDP 2312
Query: 2291 THLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPT 2350
+++ + RL+ HE RVF+DRLI+ ED+ F ++ E + F I+ P
Sbjct: 2313 GTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDLEYFLNKP- 2371
Query: 2351 GKIVDDNIRSLFFGDYFKPESDQ--KIYDEITDLKQLTVVMEHYLEEFNNISKAPMSLVM 2408
+ FGD+ K +D+ +IYD++ D+++ V++ YL+++N + + LV
Sbjct: 2372 ----------IIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVF 2421
Query: 2409 FRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGND 2468
F+ AIEH+SRI R+++Q++G+ LLVG+GG+G+QS +L+ + Y+ QIE+++ Y +
Sbjct: 2422 FQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDS 2481
Query: 2469 WREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVE 2528
+ EDL+K+ GV K+ VFLF D QI E F+EDIN +LN+G+VPN+F DE +E
Sbjct: 2482 FHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDE----LE 2537
Query: 2529 KMQTAARTQGEKVEVTPLS---MYNFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLIN 2585
++ A R + ++V ++ + ++ +FI +V K+ L MSP+G+AFR+R RMFPSL+N
Sbjct: 2538 QVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVN 2597
Query: 2586 CCTIDWFQSWPTDALELVANKFLEDVEL-DDNIRVEVVSMCKYFQESVKKLSLDYYNKLR 2644
CCTIDWF WP +AL V+ F V+ ++ ++ ++ MC SV ++ YYN+LR
Sbjct: 2598 CCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYNELR 2657
Query: 2645 RHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQ 2704
R Y TPTSYLELI + ++L+ KR+++ R+R GL KL V M+ +L+AL+
Sbjct: 2658 RRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALE 2717
Query: 2705 PQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAM 2764
P L+ SE+ +M K+ + AD + VQ DE A V A Q I ++ + DL EA+
Sbjct: 2718 PVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEAL 2777
Query: 2765 PALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSGKMIE 2824
PAL+AA ALD+L+ ADIS ++ PP V VME+I I+ KP+
Sbjct: 2778 PALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPD------------- 2824
Query: 2825 DYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGL 2884
W +K++LGD FL+ L YDK+NI P + ++ +++IN+P+F P ++ VS AC+ +
Sbjct: 2825 --WPSAKQLLGDSNFLKRLLEYDKENIKPQILAKL-QKYINNPDFVPEKVEKVSKACKSM 2881
Query: 2885 CKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFE 2944
C WVRAM++Y RV KVV PKR++LR A+ +L M L +K+A L+ V D++QAL D+++
Sbjct: 2882 CMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYD 2941
Query: 2945 EMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSG 3004
+ +K+ L + + + +LVRA KL + L E+ RW E+ ++ +N+TG+V +++
Sbjct: 2942 KGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAA 3001
Query: 3005 TVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSF 3064
VAY GAFT YR W+ +C+ IP FSL + LGDP +IR W GLP D
Sbjct: 3002 CVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLI 3061
Query: 3065 SIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTP 3124
S +NGI+V+ RRW LMIDP QAN+WI+N E + L +IK +DSN++R+LEN+++LG P
Sbjct: 3062 STENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLP 3121
Query: 3125 VLIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPE 3184
VL+E + E LD ++EPILLK F G +RLG++ I+Y ++F+ Y+TT++ NPHYLPE
Sbjct: 3122 VLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPE 3181
Query: 3185 VAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILE 3244
V +KV ++NF +T GL+DQLL V EKP LEE++ +LIV +K LK IE+KIL
Sbjct: 3182 VCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILR 3241
Query: 3245 VLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVHSATI 3304
+L S+GNIL++E I L SK+ S I + + A TE I+ R Y+PVA + +
Sbjct: 3242 MLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVM 3301
Query: 3305 FFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRS 3364
+F I+ L+ I+PMYQYSL +F L+ ++ S K+E L R+ +++ L+ Y NV R
Sbjct: 3302 YFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRG 3361
Query: 3365 LFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPY-PNPAPQWLSEKAW-AE 3422
LFE+ KL++S +L + +M+Q+ +++ W F L G L+ P P WL W A
Sbjct: 3362 LFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFAC 3421
Query: 3423 IVRASALPKLHGLMEHLEQN-----LGEWKLIYD-------SAWPHEEQLPGSWK----- 3465
+ P HGL +++ + LG ++ + S HE++ K
Sbjct: 3422 CDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQ 3481
Query: 3466 --FSQGL---EKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAP 3520
+S GL K+++++C + +K+V A+ +F+ E++GK +IE P DL Y D SC P
Sbjct: 3482 DPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTP 3541
Query: 3521 LIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQN 3580
L+F+LS +DPM +FA + G R Q+ISLGQGQGPIA KM+ +A+K G WV LQN
Sbjct: 3542 LVFILSTGSDPMGAFQRFARESGY-SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQN 3600
Query: 3581 CHLAASWMPTLEKICEEVIVPEST-NARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGL 3639
CHLA SWM +E++ + P+S FRL+L+S PS FPV++LQN +K+TNEPPKGL
Sbjct: 3601 CHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGL 3660
Query: 3640 RANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFN 3699
RAN+ R++ P FF+ W++++FG+CFFHA++QER+ FGPLGWNI YEFN
Sbjct: 3661 RANIRRAFTE---MTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFN 3717
Query: 3700 ESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEI 3759
+SD ++ ++++ + K +P+DAL Y+TGE YGGRVTD D+R L ++L F+ E
Sbjct: 3718 DSDRECALLNLKLYCKEGK-IPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPET 3776
Query: 3760 EEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFE 3819
E+ Y + Y+ P S Q + DY+ NLP+ PE+FG+HENA++ +ET+ L
Sbjct: 3777 LEEDYKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLIN 3836
Query: 3820 GVLLTLPRQS-GGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEE----SMNT 3874
+L PR S GG GKS E+V+EL + +++P ++E + V + S+ T
Sbjct: 3837 TILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTT 3896
Query: 3875 VLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPS 3934
VL QE+ RFN L K++ SL L +AI G V+MS E+E+V+NS L +VPA+W+ +YPS
Sbjct: 3897 VLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPS 3956
Query: 3935 LKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHI 3994
LKPLG +V DL+ R +F W+ +G P +WISGF+F Q FLTG QN+ARKY +PID +
Sbjct: 3957 LKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDEL 4016
Query: 3995 GFEFEVTP----QETVME-----------------NNPEDGAYIKGLFLEGARWDRKTMQ 4033
F++ V P Q V+E +PEDG + G+F++ +RWD K M
Sbjct: 4017 SFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMV 4076
Query: 4034 IGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIE 4093
I ++LP + LP++ +P ++ +Y CP+YKT AR GTLSTTGHSTN+V+++
Sbjct: 4077 IEDALPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVL 4135
Query: 4094 LPTDMPQKHWINRGVASLCQL 4114
LP+ + +WI +G A LCQL
Sbjct: 4136 LPSKRSKDYWIAKGSALLCQL 4156
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 2425 bits (6285), Expect = 0.0
Identities = 1361/3569 (38%), Positives = 2063/3569 (57%), Gaps = 154/3569 (4%)
Query: 606 YLNVYKKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNITVPLAMFC 665
YL + Y ++ + + I + + N + FV I + N + +
Sbjct: 955 YLKTWDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVL 1014
Query: 666 LDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKEL--- 722
LD + L L + ++ ++ + A+K+S P +EL
Sbjct: 1015 LDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVS 1074
Query: 723 VSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDYADLPYQ--IEDIFDN---------- 770
+ L++ LK A + Q+ E+ L Y ++P + + ++ D+
Sbjct: 1075 LQLVDALKHDLA----NVETQIPPIHEQFAILEKY-EVPVEDSVLEMLDSLNGEWVVFQQ 1129
Query: 771 ----SRNLLLHKRDQAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLN 826
S+ +L +++ + LI +F+ + H LE F + T+ NV ++
Sbjct: 1130 TLLDSKQMLKKHKEKFKTGLIHSADDFKKKA---HTLLEDFEFKGHFTS-----NVGYMS 1181
Query: 827 ELSKNLNRAFAEFELINKEEELLEKEKSTYPL-------LQAMLKNKVPYEQLWSTAYEF 879
L + + + A + +EE L + + LQ + K +Q+W A ++
Sbjct: 1182 ALDQ-ITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDW 1240
Query: 880 SIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQ 939
EW G +L E + ++R KL K D + E + KI++FK+
Sbjct: 1241 EENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKD--RNWEIIETTRSKIEQFKR 1298
Query: 940 YIPILSISCNPGMKDRHWQQISEIVGYEI-KPTETTCLSNMLEFGFGKFVEKLEPIGAAA 998
+P++S NP +++RHW Q+ + + E + +E+ L ++E G + VEK+ I A+A
Sbjct: 1299 TMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASA 1358
Query: 999 SKEYSLEKNLDRMKLDWVNVTFSFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPF 1058
+KE ++E L + W V Y+D + L +++ L+D+ + TM S F
Sbjct: 1359 TKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRF 1418
Query: 1059 IKPIEAECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDS 1118
+K E + WE L I + ++ L Q W+YLE IF EDI Q+P E F V+S
Sbjct: 1419 VKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNS 1478
Query: 1119 YWKSLMSQAVKDNRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLS 1178
WK++M + KDN L + P + + L E N +LEDIQK L+ YLE KR FPRF+FLS
Sbjct: 1479 NWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLS 1538
Query: 1179 NDELLEILSETKDPLRVQPHLKKCFEGIAKLEF------TDNLEIVGMISSEKETVPFIQ 1232
ND+LLEIL ++++P VQPHLKKCF+ I L + E VGM S + E + F+
Sbjct: 1539 NDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLH 1598
Query: 1233 KIYPANAKGMVEKWLQQVEQMMLASMREVIG---LGIEAYVKVPRNHWVLQWPGQVVICV 1289
++ +G VE WL VEQ M ++R+++ L + ++ R+ WV +W GQVVI
Sbjct: 1599 SVF---LEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLN-KRDKWVKEWAGQVVITA 1654
Query: 1290 SSIFWTQEVSQAL------AENTLLDFLKKSNDQIA-QIVQLVRGKLSSGARLTLGALTV 1342
S I WT +V++ L A+ +L +KK+ I + + +RG L+ RL + AL
Sbjct: 1655 SQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVT 1714
Query: 1343 IDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAK--DVQVQIITTEALYGYEYLGNSP 1400
I++HARDV+ KL + + D+N F W+SQLR+YW D ++ T+ Y YEYLGNS
Sbjct: 1715 IEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSG 1774
Query: 1401 RLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLD 1460
RLVITPLTDRCY TL AL L+ GG+P+GPAGTGKTET KDL KAL +V NCS+GLD
Sbjct: 1775 RLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLD 1834
Query: 1461 YKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELS 1520
YK+MG+ + GLAQ GAW CFDEFNRI +EVLSVVA QIL I A+ L F F+G E++
Sbjct: 1835 YKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEIN 1894
Query: 1521 LNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQ 1580
L +C +FITMNPGYAGR ELP+NLK++FR +AM+VPD LI EI L+ GF + + LA+
Sbjct: 1895 LVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAK 1954
Query: 1581 KIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAK 1640
K+ Y L +QLS Q HYD+G+RA+ S+L AG + P+ + +LL ++ D+N+AK
Sbjct: 1955 KVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAK 2014
Query: 1641 FLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMM 1700
+ D PLF I+ DLFP + LP DY + + I+ M LQ P+ + K+ Q+YE
Sbjct: 2015 LTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETK 2074
Query: 1701 LVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCF 1760
RH MIVG GKT+++++L A+L L A V +NPKA+++G+LYG +
Sbjct: 2075 NSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEY 2134
Query: 1761 DQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGE 1820
D ++EW DG+L++ R + D KWI+FDGPVD +WIENMN+V+DDNK L L++GE
Sbjct: 2135 DLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGE 2194
Query: 1821 IIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHK 1880
I M ++SL+FE DL ASPATVSRCGM+Y + LGWKP S+++ P K
Sbjct: 2195 RIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRP----KAEV 2250
Query: 1881 ELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGE 1940
E + MF L+ L F + +CK +V S+ +LYS+L A E + +
Sbjct: 2251 EPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSAL-----ATPENGVNPAD 2305
Query: 1941 GLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTK 2000
G + ++ F+FS++W+V +++ + RK+ D + R +
Sbjct: 2306 G---ENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREI------------------ 2344
Query: 2001 NNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFL 2060
FP + ++Y+ YF+ W ++ + K + P A ++++PT++T R ++ +
Sbjct: 2345 EGSFPNKDTVYE-YFVDPKIRSWTSFEDKLPK-SWRYPPNAPFYKIMVPTVDTVRYNYLV 2402
Query: 2061 KTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKL 2120
+ + ++ P+L VGP GTGK++I + L LP + + +N SA+T++N Q II S++
Sbjct: 2403 SSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRV 2462
Query: 2121 DRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDI 2180
++R KG++ P GK + F+DDLNMPAK+++G+QPP+EL+R WID+G+W+D+ T I
Sbjct: 2463 EKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYI 2522
Query: 2181 VDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHFGKGFDVMF 2240
+M L+ AMGPPGGGR I+ R NII++ + +IF ++++ + F+
Sbjct: 2523 REMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKL-QDFEEEV 2581
Query: 2241 LRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCI 2300
G ++ +AT +Y V+ FLPTP+K HY+FNLRD S+V QG+L
Sbjct: 2582 KPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSIT 2641
Query: 2301 RLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRS 2360
RLWIHE +RVF DRL+D D + F ++ + + F T HL P+ R
Sbjct: 2642 RLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFH----HLCPSK-------RP 2690
Query: 2361 LFFGDYFKPESDQKIYDEITDLKQLTVVMEHYLEEFN-NISKAPMSLVMFRFAIEHISRI 2419
FGD+ K + K+Y+++TDL L VME L E+N + S PM LV+FR AIEHI+RI
Sbjct: 2691 PIFGDFLK---EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRI 2747
Query: 2420 CRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQ 2479
RV+ Q +G++LLVGIGGSGRQS A+L++ + Y +QIE+TK+Y ++R+D+K++ Q
Sbjct: 2748 VRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQ 2807
Query: 2480 VGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGE 2539
GV K+T F+F D QI DESF+EDIN +L++G+VPN++ DE +I + AR E
Sbjct: 2808 AGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARV--E 2865
Query: 2540 KVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDA 2599
+V + S++ + IERV N + L +SP+GD FRN +R +P+L+NC TI+WF WP +A
Sbjct: 2866 QVPESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEA 2925
Query: 2600 LELVANKFLEDVEL--DDNIRVEVVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLEL 2657
L VA K L V+L +NI +V + SV + S +LRRHNYVTPT YLEL
Sbjct: 2926 LLEVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLEL 2985
Query: 2658 ILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKM 2717
+ +K LL KRQE+ N+ TGL K+D +V VM EL + ++ ++ +
Sbjct: 2986 LSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEY 3045
Query: 2718 MVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTL 2777
+V I + READ ++ V A+ ++ V Q + + + DL EA+PALE A+ AL++L
Sbjct: 3046 LVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESL 3105
Query: 2778 NPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDL 2837
N DI +KS PP V++VM+++ I++G +P W +K+ LG+
Sbjct: 3106 NKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPT---------------WAEAKRQLGEQ 3150
Query: 2838 KFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRV 2897
F++SL +DKDNI +K+I + P+FQP +I VS A + LC WVRAME+Y R+
Sbjct: 3151 NFIKSLINFDKDNISDKVLKKI-GAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRL 3209
Query: 2898 AKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENI 2957
+VV PKR R+ A +L + L + + +L+ V ++L+ L ++E +K++L +
Sbjct: 3210 YRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKS 3269
Query: 2958 EICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYR 3017
E KL RA L+SGL GEK RW E + L L GD LL++ ++Y+G F +YR
Sbjct: 3270 EEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYR 3329
Query: 3018 VQCQNQ-WLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSR 3076
+ NQ W+ + + +P F++ + L +P K+R W I GLP D+FS +NGIIV+
Sbjct: 3330 DEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGN 3389
Query: 3077 RWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDA 3136
RWALMIDP QA KWIKNME L +I S+Y+R+LE+A+ G PVL++N+ E LD
Sbjct: 3390 RWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDP 3449
Query: 3137 SIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMI 3196
++ P+L K+ + G MR+G+ +EY+ +F+ YITT+L NPHY PE + K ++NF +
Sbjct: 3450 TLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAV 3509
Query: 3197 TPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILED 3256
GL+ QLLGIV KE+PELEE+K+ L++ A K+ LKE+ED+IL +L+ + G++L+D
Sbjct: 3510 KEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDD 3569
Query: 3257 ETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEP 3316
+ L +SK+ + E++E+ + + TE D R Y+P A ++ +FF ++D+ I+P
Sbjct: 3570 VQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDP 3629
Query: 3317 MYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLL 3376
MYQ+SL +I+L++ S+ S +S +L RI Y+ D+ T ++Y CR+LFE+ KLLFS
Sbjct: 3630 MYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFH 3689
Query: 3377 LTIGIMKQKKEITEEVWYFLLTGGIALD--NPYPNPAPQWLSEKAWAEIVRASALPKLHG 3434
+ I++ ++ + + F L GG+ LD NP WL++ W I L HG
Sbjct: 3690 MCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHG 3749
Query: 3435 LMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFS-QGLEKMVILRCLRPDKMVPAVREFIA 3493
LM EQ +W L Y +A P + LPG W+ + +++M+I+R LR D++ V FI
Sbjct: 3750 LMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFII 3809
Query: 3494 EHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTIS 3553
++G +IE P +++ DS+ +PL+F+LSP DP + LL+ A+ +GM R +S
Sbjct: 3810 TNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGM-AQRFHALS 3868
Query: 3554 LGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLT 3613
LGQGQ PIAA+++ + G WV L NCHL+ SWMP L+K+ E++ V E + FRLWL+
Sbjct: 3869 LGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQV-EDPHPSFRLWLS 3927
Query: 3614 SYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFG 3673
S P FP+SILQ IKMT EPPKGL+AN+ R Y +S+P F C+K ++K+LF
Sbjct: 3928 SIPHPDFPISILQVSIKMTTEPPKGLKANMTRLY--QLMSEPQ-FSRCSKPAKYKKLLFS 3984
Query: 3674 LCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECN 3733
LCFFH+V+ ER+ F LGWNI Y FN+SD +S + ++L++Y+E P+DAL YL N
Sbjct: 3985 LCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGIN 4044
Query: 3734 YGGRVTDDKDRRLLLSLLSMFYC-KEIEEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPI 3792
YGG VTDD DRRLL + ++ ++C + + ++ L+ +TY+IP GS SY +Y+ LP
Sbjct: 4045 YGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPG 4104
Query: 3793 TAHPEVFGLHENADITKDNQETNQLFEGVLLTLPR--QSGGSGKSPQEVVEELAQDILSK 3850
PE FG H NAD+ E LF+ +L P+ + G++ +E V ELA D+ K
Sbjct: 4105 MDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLELAADVKQK 4164
Query: 3851 LPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSE 3910
+P D E KL + +N VL QE+ R+N L + + SL +L + I+G ++MS+
Sbjct: 4165 IPEMIDYEGTQKLL-ALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTS 4223
Query: 3911 LEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKG-PPVVFWISGF 3969
LEE+FN + VP +W K+YPS KPL + DL R+ F+ W + PPV+FW+SGF
Sbjct: 4224 LEEIFNCIFDAHVPPLW-GKAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGF 4282
Query: 3970 YFTQSFLTGVSQNYARKYTIPIDHIGFEFEV-TPQETVMENNPEDGAYIKGLFLEGARWD 4028
F FLT V Q+ AR+ + +D + +EF V T ++ + P+DG +++GL+LEGA WD
Sbjct: 4283 TFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWD 4342
Query: 4029 RKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNY 4088
RK + E+ P L +P I +P ES + +Y CP Y R G + ++
Sbjct: 4343 RKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAG----SSDRASF 4398
Query: 4089 VLSIELPTD-MPQKHWINRGVASLCQLDN 4116
V+ I+L + M HWI RG A L LD+
Sbjct: 4399 VIGIDLRSGAMTPDHWIKRGTALLMSLDS 4427
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 2012 bits (5212), Expect = 0.0
Identities = 1223/3491 (35%), Positives = 1902/3491 (54%), Gaps = 148/3491 (4%)
Query: 680 QNLKDHLIQFQVDVNRDTNTSICN---QYSHIADKVSEVPANTKELVSLIEFLKK-SSAV 735
+N K +I +N + N + H+A + ++P ++L ++ + + S
Sbjct: 1060 ENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKS 1119
Query: 736 TVFKLRRQLRDASERLEFLMDY--------ADLPYQIEDIFDNSRNLLLHKRDQAEMDLI 787
V +LR RD ER + Y +L +IE I+ N N ++ + A D+
Sbjct: 1120 LVMELR--YRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDSVNV-EHALGDIK 1176
Query: 788 KRCSEFEL-RLEGYHRELESFRKREVM-----TTEEMKHNVEKLNELSKNLNRAFAEFEL 841
+ +E + Y ++E F KR +++ VE L + L R +
Sbjct: 1177 RTFTELTRGEIMNYRVQIEEFAKRFYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQE 1236
Query: 842 INKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAE 901
+ E+L + + YP L + K ++ + EEW LN + + E
Sbjct: 1237 LANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQE 1296
Query: 902 EIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQIS 961
I R KL + + + L + K+ FK IP+L N ++DRHW+++
Sbjct: 1297 GIEGFLRALRKLPRPVRGLSVTYYL----EAKMKAFKDSIPLLLDLKNEALRDRHWKELM 1352
Query: 962 EIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFS 1021
E + TET L NM K + L I AA KE ++EK + + W N+ F+
Sbjct: 1353 EKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFT 1412
Query: 1022 FVKY-RDTDTN--ILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQD 1078
VKY + T IL ++D+I LDD+ Q++ GS F+ P KWE+ L I +
Sbjct: 1413 VVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGE 1472
Query: 1079 NLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAAD 1138
++ W+ Q W+YLE IF DI +Q+PEE +KF +D +K +M + +KD I +
Sbjct: 1473 VIEIWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCE 1532
Query: 1139 QPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPH 1198
P LQ + LE QK LNDYL+ KR FPRFFF+S+DELL IL + DPL VQ H
Sbjct: 1533 APNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEH 1591
Query: 1199 LKKCFEGIAKLEFTDNLE----IVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMM 1254
+ K ++ IA L F D + MIS+E E + F +KI A+G VE W+ V M
Sbjct: 1592 MIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEF-RKIL--RAEGRVEDWMTAVLNEM 1648
Query: 1255 LASMREVIGLGIEAYVKV-PRNHWVLQWPGQVVICVSSIFWTQEV------SQALAENTL 1307
+ R + I Y + R W+L + G VV+ S ++WT EV +Q + +
Sbjct: 1649 RRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAM 1708
Query: 1308 LDFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQW 1367
++ +K + QI ++V + LS R + +IDVHARD+V + + +F W
Sbjct: 1709 KNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDW 1768
Query: 1368 ISQLRYYWVAK--DVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGG 1425
SQLR+YW + ++ ++ T YGYEY+G + RLVITPLTDR Y TL AL + LGG
Sbjct: 1769 ESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGG 1828
Query: 1426 APEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNR 1485
AP GPAGTGKTETTKDLAKAL CVV NC +G+DY+A+GK F GLAQ GAW CFDEFNR
Sbjct: 1829 APAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNR 1888
Query: 1486 IEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNL 1545
I+ VLSV++ QI +I+ A+I +L TF FEG E+SL+ +FITMNPGYAGR ELP+++
Sbjct: 1889 IDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESV 1948
Query: 1546 KALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRA 1605
KALFR V ++VPD I EI L+S GFL++++LA+K+ Y+L EQLS Q+HYD+G+RA
Sbjct: 1949 KALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRA 2008
Query: 1606 VKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKP 1665
+KSVL AG LK + E V+L+RAL D+NL KF+ +DVPLF G+ISDLFPG+ P+
Sbjct: 2009 LKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRV 2068
Query: 1666 DYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAA 1725
Y F + +++ +P + K++Q++E ML RH M+VG GGK+ L
Sbjct: 2069 RYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQ 2128
Query: 1726 ALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFRE-QASSLS 1784
A L ++ I+NPKA+++ +LYG D + +W DGVL+N FRE +
Sbjct: 2129 AQTKLGLTTKL-------YILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDK 2181
Query: 1785 DDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPAT 1844
+RK+I+FDG VDA+W+ENMN+V+DDN+ L L +GE I++ + +L+FE DL+ ASPAT
Sbjct: 2182 KERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPAT 2241
Query: 1845 VSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKF 1904
VSRCGM+Y++P L ++P +++ +P+ + + + + + ++ + + G + +
Sbjct: 2242 VSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQ 2301
Query: 1905 VVQTSPI--HLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWT 1962
+ I +M+ + +LD + E E+++L L+ FL +L +
Sbjct: 2302 AEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLDL------------LECYFLEALYCS 2349
Query: 1963 VAGTINADSRKKFDVFFRNL--IMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQAS 2020
+ ++ D R KFD + + L + +D + V + + ++YDF+F + +
Sbjct: 2350 LGASLLEDGRMKFDEYIKRLASLSTVD-----TEGVWANPGELPGQLPTLYDFHFDNKRN 2404
Query: 2021 GHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGK 2080
W W++ + E P K +++ T++T R ++ L+ + + P++FVG +GT K
Sbjct: 2405 -QWVPWSK-LVPEYIHAPE-RKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSK 2461
Query: 2081 SAITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFV 2140
+A T NFL +L + T + +NFS+RT++ Q + + +++R K +GPP+GK+ +VF+
Sbjct: 2462 TATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFM 2521
Query: 2141 DDLNMPAKEVYGAQPPIELLRQWIDHGYWFDK-KDTTRLDIVDMLLVTAMGPPGGGRNDI 2199
DD+NMP + YG Q PI LL+ ++ GY +D+ K+ I D+ + AMG GGGRN++
Sbjct: 2522 DDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEV 2581
Query: 2200 TGRFTRHLNIISINAFEDDILTKIFSSIVDWHFGKGFDVMFLRYGKMLVQATKTIYRDAV 2259
RF ++ ++ ++ L I+SSI+ H + + GK L T +Y++ V
Sbjct: 2582 DPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGK-LTFCTLALYKNIV 2640
Query: 2260 ENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKE 2319
++ PTPSK HY+FNLRD SRV G++L Q V + +R+W +E RVF+DRLI +
Sbjct: 2641 QDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISET 2700
Query: 2320 DRQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKP--ESDQKIYD 2377
D+Q+ + FK +E V+ + FGD+ E + +IY+
Sbjct: 2701 DKQLVQQHIGSLVVEHFKDDVEVVMRD-------------PILFGDFQMALHEGEPRIYE 2747
Query: 2378 EITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGG 2437
+I D + + + LEE+N S M+LV+F A+EH++R+ R+++ D+GH LLVG+GG
Sbjct: 2748 DIQDYEAAKALFQEILEEYNE-SNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGG 2806
Query: 2438 SGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIK 2497
SG+QS ++L+ F + E+++I +++ Y+ N +REDLK + L++G+ K+ +FLF D +
Sbjct: 2807 SGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVA 2866
Query: 2498 DESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVI 2557
+E F+E IN +L +G VP +F +EK I+ ++ A QG + S++ +F+ +
Sbjct: 2867 EEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQG--MGPAKESVWQYFVNKSA 2924
Query: 2558 NKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNI 2617
N + L MSP+GD R R FP ++N IDWF WP AL VA FL +
Sbjct: 2925 NNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAE 2984
Query: 2618 RVE-VVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMR 2676
+E VV +SV S + KLRR NYVTP +YL+ I T+ LL+ K Q
Sbjct: 2985 NIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQC 3044
Query: 2677 NRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQ 2736
R GL KL A Q+ + ++L + L S ++ +I T A+ KK L +
Sbjct: 3045 KRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAE 3104
Query: 2737 ADEKEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVK 2796
E + K E E LAE MP LEAA L L+ +D++ ++S PP V+
Sbjct: 3105 EKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQ 3164
Query: 2797 LVMESICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTM 2856
V E I IMKG K E W +K ++ D FL SL D D+I +
Sbjct: 3165 TVCECILIMKGYK--------------ELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQV 3210
Query: 2857 KRIRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLA 2916
K I+ + ++ VS A G+ K+V A+ Y V + + PKRE++ E
Sbjct: 3211 KNIK-GLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFY 3269
Query: 2917 AQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGG 2976
++L + + EL + L+ L +E +K+ L+E EI ++L+ A+KLISGLG
Sbjct: 3270 LTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGS 3329
Query: 2977 EKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQ-WLAECKDKVIPG 3035
E RW +L R L GD LL + ++Y GAFT ++R + N+ W + ++ IP
Sbjct: 3330 ENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPL 3389
Query: 3036 FSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNM 3095
F L L D ++I W GLP D S+ NGI+ + + R+ L IDP QA WIK
Sbjct: 3390 SQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRK 3449
Query: 3096 EKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYM 3155
E+ N L V F+D ++++ LE +++ GTP L ++ E +D I+ +L K QG +++
Sbjct: 3450 EEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFI 3509
Query: 3156 RLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKP 3215
LG+ ++Y +F+LY+ T+L NP Y P V K ++N+ +T GL+DQLL ++ A E+
Sbjct: 3510 ILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERR 3569
Query: 3216 ELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISE 3275
ELEE++ LI E+++NK LK++ED +L L+ S GN+L++ + L +K + E+SE
Sbjct: 3570 ELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSE 3629
Query: 3276 KQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTH 3335
K K+A T ID R GY+P A A +FF +S++A + MYQYSL F+ ++ SL
Sbjct: 3630 KLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKK 3689
Query: 3336 STKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYF 3395
S L R++ I+D T SIYN+ C LFE+ KLLFS +TI I + + + +E F
Sbjct: 3690 SLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDF 3749
Query: 3396 LLTGGIALDNPYPNPAPQWLSEKAWAEIVRASAL--PKLHGLMEHLEQNLGEWKLIYDSA 3453
L G I+L+ WLS++ W +I+ S + L + +E N W+ YD
Sbjct: 3750 FLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYD-- 3807
Query: 3454 WPHEEQLPGSWKFSQGL---EKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQG 3510
EQ P + + +K++ILRC R D++ AV +++ MG+ Y++ P +
Sbjct: 3808 LDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEA 3867
Query: 3511 SYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAI 3570
+ S+ +P++F+LSP +DP L+K A+ G GG R + +++GQGQ +A +++ A+
Sbjct: 3868 IFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAV 3927
Query: 3571 KDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIK 3630
G W++LQNCHL W+ LEK E + P + FRLWLT+ P++ FP+ ILQ +K
Sbjct: 3928 ARGQWLMLQNCHLLVKWLKDLEKSLERITKP---HPDFRLWLTTDPTKGFPIGILQKSLK 3984
Query: 3631 MTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPL 3690
+ EPP GL+ N+ +Y IS + Q A ++ +++ L FFHAVVQERR FG +
Sbjct: 3985 VVTEPPNGLKLNMRATYFK--ISHEMLDQCPHPA--FKPLVYVLAFFHAVVQERRKFGKI 4040
Query: 3691 GWNIPYEFNESDLRISMWQIQMFLNDY-----KEVPFDALTYLTGECNYGGRVTDDKDRR 3745
GWN+ Y+FNESD ++ M + +L +P+ +L YL GE YGGR D DRR
Sbjct: 4041 GWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRR 4100
Query: 3746 LLL----SLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGL 3801
+L L F + ++ Y IP + +++ + LP+ PEVFGL
Sbjct: 4101 ILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGL 4160
Query: 3802 HENADITKDNQETNQLFEGVLLTLPRQSG--GSGKSPQEVVEELAQDILSKLPRDFDLEE 3859
H NA+I Q ++ LL L Q+G SG S + + ++A++I +K+P+ FDL++
Sbjct: 4161 HPNAEIGYYTQAARDMW-AHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQ 4219
Query: 3860 VMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSML 3919
V K + + VL QEL RFN+L + +SL L RA+ G+V MS+EL++V S+
Sbjct: 4220 VRKRLGTGLSPT-SVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLF 4278
Query: 3920 VGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGV 3979
+G +P +W + +LK LG ++ L R + + W+ + P V W+SG + +S+LT +
Sbjct: 4279 IGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTAL 4338
Query: 3980 SQNYARKYTIPIDHIGFEFEVTPQETVMENNPE--DGAYIKGLFLEGARWDRKTMQIGES 4037
Q RK P+D +VT + E N G ++ GL+LEGA WD + + +S
Sbjct: 4339 VQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKS 4398
Query: 4038 LPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTD 4097
PK+L LPI+ + P E+ Q+ + PVY TS RR + V +L T
Sbjct: 4399 KPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM-----GVGLVFEADLFTT 4453
Query: 4098 MPQKHWINRGV 4108
HW+ +GV
Sbjct: 4454 RHISHWVLQGV 4464
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 1938 bits (5020), Expect = 0.0
Identities = 1174/3373 (34%), Positives = 1811/3373 (53%), Gaps = 155/3373 (4%)
Query: 786 LIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAEFELINKE 845
L ++C +FEL+ H E FR RE + + + LN+ K+++ E ++K
Sbjct: 1209 LRRKCQQFELK---QHEFRERFR-REAPFSFSDPNPYKSLNKQQKSISAMEGIMEALSKS 1264
Query: 846 EELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEEIGN 905
L E Y L+A + ++LW + E+W +N EQ+ +
Sbjct: 1265 GGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKK 1324
Query: 906 MWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISEIVG 965
+ L K + A L VK I + +S NP +++RHWQQ+ +
Sbjct: 1325 FAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPAIRERHWQQLMQATQ 1380
Query: 966 YEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVKY 1025
+ K +E T L+++L+ + +++ I A KE +EK L + W + F +
Sbjct: 1381 VKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPH 1440
Query: 1026 RDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLK 1085
T T +L + + + L+D+ ++ Q + S ++ E W++KL + W +
Sbjct: 1441 PRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFE 1500
Query: 1086 CQATWLYLEPIF-SSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPRMAE 1144
Q TW +LE IF SEDI Q+P + ++F ++ +K+LM AVK ++ A +P +
Sbjct: 1501 VQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYN 1560
Query: 1145 KLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKKCFE 1204
KL+ L +K L +YLE KRL FPRF+F+S+ +LL+ILS DP+ V HL K F+
Sbjct: 1561 KLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFD 1620
Query: 1205 GIAKLEFTDN-----LEI-VGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASM 1258
+ KL+F + L++ +GM S E E + F Q+ + G VE WL +V M +++
Sbjct: 1621 SLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQE---CDLSGQVEVWLNRVLDRMCSTL 1677
Query: 1259 REVIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALA------ENTLLDFLK 1312
R I + Y + PR W+L +P QV + + I+WT EV A A EN + D+ K
Sbjct: 1678 RHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNK 1737
Query: 1313 KSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLR 1372
K Q+ ++ L+ G L++G R+ + + IDVHARDVVAK+ +V F W +QLR
Sbjct: 1738 KQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLR 1797
Query: 1373 YYW--VAKDVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGP 1430
+ W + I + Y YEYLGN+PRLVITPLTDRCY TL +L L +GGAP GP
Sbjct: 1798 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP 1857
Query: 1431 AGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEV 1490
AGTGKTETTKDL +AL VFNCS+ +DYK+ G +KGLAQ GAW CFDEFNRI VEV
Sbjct: 1858 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV 1917
Query: 1491 LSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFR 1550
LSV+A Q+ +Q AI K K F F G + L PT +FITMNPGYAGRAELP+NLKALFR
Sbjct: 1918 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR 1977
Query: 1551 TVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVL 1610
AM+VPD+ LI EI L + GFL++R LA+K + Y LC E LS Q HYD+G+RA+KSVL
Sbjct: 1978 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 2037
Query: 1611 TAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVF 1670
AG+LK P E +L+RAL D N+ K + D+P+F G+I DLFP + +P+ F
Sbjct: 2038 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF 2097
Query: 1671 LKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDL 1730
K++ +I ++KLQ F+ K++Q+ E++ VRH IVG+ GK+ K L +L
Sbjct: 2098 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL 2157
Query: 1731 HAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWI 1790
+ + AV+ ++PKA+T +L+G + V+ EW DG+ + R+ A+ D KWI
Sbjct: 2158 ----KRKPVAVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWI 2210
Query: 1791 IFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGM 1850
I DG +D +WIE++NTV+DDNK L L S E I +N M L+FE + L A+PATVSR G+
Sbjct: 2211 ILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGI 2270
Query: 1851 IYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSP 1910
+Y+ P LGW P+ S+++ K + ++ D ++ CL+ R K +
Sbjct: 2271 LYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYL---PTCLDKLRFGFKKITPVPE 2327
Query: 1911 IHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINAD 1970
I + +++ L LL E + EL E F+F+ W G + D
Sbjct: 2328 ITVIQTILYLLECLLTEKTVPPDSPRELYE------------LYFVFTCFWAFGGAMFQD 2375
Query: 1971 SRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYI 2030
+ V F + K++K FP +G+I+D Y+I + + WT +
Sbjct: 2376 QLVDYRVEFSKWWIN------EFKTIK------FPSQGTIFD-YYIDPDTKKFLPWTDKV 2422
Query: 2031 TKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLH 2090
E + + ++ T ET R +F+ ++ P++ VG GTGKS + + L
Sbjct: 2423 PSFE--LDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLES 2480
Query: 2091 LPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEV 2150
L + YL + F+ T++ Q ++ L+++ +GPP KK V F+DD+NMP +
Sbjct: 2481 LNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDK 2540
Query: 2151 YGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNII 2210
YG P L+RQ +DH +W+D+ T DI + V M P G I R RH +
Sbjct: 2541 YGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHFCVF 2599
Query: 2211 SINAFEDDILTKIFSSIVDWHFG-KGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKS 2269
+++ + LT I+++I+ H + + R LV A +++ FLPT K
Sbjct: 2600 AVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKF 2659
Query: 2270 HYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVK 2329
HYVFNLRD S + QG+L L+ +RLW+HE RV+ D+++D++D++ +
Sbjct: 2660 HYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTM 2719
Query: 2330 ETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVM 2389
+T F +++L + F + + D K Y +TD+ L ++
Sbjct: 2720 ASTKKFFDDLGDELLF------------AKPNIFCHFAQGIGDPK-YVPVTDMAPLNKLL 2766
Query: 2390 EHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTF 2449
L+ +N ++ A M+LV+F A+ HI RI R+L+ +G+ LLVG+GGSG+QS ++L+ +
Sbjct: 2767 VDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAY 2825
Query: 2450 MNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLL 2509
++ +++QI + K Y D + DL ++ V +VFL D+Q+ +E F+ IN LL
Sbjct: 2826 ISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLL 2885
Query: 2510 NTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPI 2569
+G++P +F DE +I+ M+ ++ G + T + + FFIE+V ++ L SP+
Sbjct: 2886 ASGEIPGLFMEDEVENIISSMRPQVKSLG--MNDTRETCWKFFIEKVRRQLKVILCFSPV 2943
Query: 2570 GDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEVVSMCKYFQ 2629
G R R R FP+++NC IDWF WP DAL V+ +FLE+ E I+ + Y
Sbjct: 2944 GSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPVIKASISFFMSYVH 3003
Query: 2630 ESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFA 2689
+V ++S Y RR+NY TP ++LE I ++ LL KR E+ R GL KL
Sbjct: 3004 TTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQST 3063
Query: 2690 ASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIA 2749
ASQV ++ +L + +L +E +++ + E + +K + +E + V
Sbjct: 3064 ASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNV 3123
Query: 2750 QGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMK 2809
+ CE DLA+A PAL AA ALDTLN +++ +KS +PP V V ++ I+
Sbjct: 3124 TEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL---- 3179
Query: 2810 PERKPDPSGSGKMIED-YWGVSKKILGDL-KFLESLKTYDKDNIPPLTMKRIRERFINHP 2867
+ GK+ +D W +K ++G + FL+SLK +DK++IP +K + + +P
Sbjct: 3180 ------TAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQGNP 3232
Query: 2868 EFQPAVIKNVSSACEGLCKW----VRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLN 2923
F P I++ S+A GLC W VR EVY VAPKR+ L EA +LA +KL+
Sbjct: 3233 TFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD----VAPKRQALEEANAELAEAQEKLS 3288
Query: 2924 QKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTE 2983
+ + ++ + L L FE+ +K ++ + ++ ++ A +L+ GL E RW E
Sbjct: 3289 RIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAE 3348
Query: 2984 AARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQ-WLAECKDKVIP-----GFS 3037
+ + L GDVLL S V+Y+G FT YR + + W+ + +P G
Sbjct: 3349 SVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLD 3408
Query: 3038 DFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEK 3097
SL L D + W GLP D S +N I+ N+ RW L++D Q KWIKN +
Sbjct: 3409 PLSL---LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYR 3465
Query: 3098 ANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRL 3157
++L I+ +Y+ ++E A+ G +LIENIGE +D ++P+L + T K+ +Y+++
Sbjct: 3466 -SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--KYIKI 3522
Query: 3158 GENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPEL 3217
G+ +EY F+L + T+ NPHY PE+ + L+NF++T GL+DQLL V AKE+P+L
Sbjct: 3523 GDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDL 3582
Query: 3218 EEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQ 3277
E+ K L + K LKE+ED +L LS + GN L D ++ L ++K + EI EK
Sbjct: 3583 EQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKV 3642
Query: 3278 KVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHST 3337
A +TE +I+E R Y+P A ++ ++F ++DL I P+YQ+SL F ++ ++ +T
Sbjct: 3643 VEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTT 3702
Query: 3338 KSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLL 3397
+ E+ R+ + D T S+Y R LFE+DKL+F +T ++ KKE+ FLL
Sbjct: 3703 PANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLL 3762
Query: 3398 TGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHE 3457
P +L + W I S + + L +E + WK + +S P +
Sbjct: 3763 RFPFKAGVVSP---VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEK 3819
Query: 3458 EQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSC 3517
E P WK L+K+ ++RCLRPD+M A++ F+ E MG ++E + + SY +SS
Sbjct: 3820 EIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSP 3879
Query: 3518 CAPLIFVLSPSADPMAGLLKFADDLG--MGGTRTQTISLGQGQGPIAAKMINNAIKDGTW 3575
+ F+LSP DP+ + LG + + +SLGQGQ +A ++ A + G W
Sbjct: 3880 STSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHW 3939
Query: 3576 VVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEK-----FPVSILQNGIK 3630
V+LQN HL A W+ TL+K E ++ +R+++++ P+ P IL+N IK
Sbjct: 3940 VILQNIHLVARWLGTLDKKLER--YSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIK 3997
Query: 3631 MTNEPPKGLRANL---LRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNF 3687
+TNEPP G+ ANL L + D + + C K + ++ MLF LC+FHAVV ERR F
Sbjct: 3998 ITNEPPTGMHANLHKALDLFTQDTL------EMCTKEMEFKCMLFALCYFHAVVAERRKF 4051
Query: 3688 GPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLL 3747
G GWN Y FN DL IS+ + +L +VP+D L YL GE YGG +TDD DRRL
Sbjct: 4052 GAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLC 4111
Query: 3748 LSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYL-RNLPITAHPEVFGLHENAD 3806
+ L+ + E+ E LAPG + IPP+ Y+ Y +Y+ NLP P ++GLH NA+
Sbjct: 4112 RTYLAEYIRTEMLEGDVLLAPG--FQIPPNLDYKGYHEYIDENLP-PESPYLYGLHPNAE 4168
Query: 3807 ITKDNQETNQLFEGVLLTLPRQS---GGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKL 3863
I + +LF VL P+++ G+G S +E V+ + DIL K+P F++ E+M
Sbjct: 4169 IGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMA- 4227
Query: 3864 YPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKV 3923
+ V QE R N LT +RRSL L +KG++ +++++E++ ++ V
Sbjct: 4228 -KAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTV 4286
Query: 3924 PAMWAAKSYPSLKPLGGYVADLLARLTFFQEW-IDKGPPVVFWISGFYFTQSFLTGVSQN 3982
P W A++YPS+ L + ADLL R+ + W D P W++GF+ QSFLT + Q+
Sbjct: 4287 PDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQS 4346
Query: 3983 YARKYTIPIDHIGFEFEVTPQETV-MENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKI 4041
ARK P+D + EVT + M P +G+Y+ GLF+EGARWD +T I E+ K
Sbjct: 4347 MARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKE 4406
Query: 4042 LYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQK 4101
L +P+I++K ++IY CPVYKT R T YV + L T
Sbjct: 4407 LTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAA 4457
Query: 4102 HWINRGVASLCQL 4114
WI VA L Q+
Sbjct: 4458 KWILAAVALLLQV 4470
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 1923 bits (4982), Expect = 0.0
Identities = 1158/3432 (33%), Positives = 1838/3432 (53%), Gaps = 152/3432 (4%)
Query: 720 KELVSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDYA-DLPYQIEDIFDNSRNLLLHK 778
K+ + L++ ++ TVFK QL + E+ + A + Q+ + N LL
Sbjct: 1170 KQTIELLKTYEQELPETVFK---QLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLR-- 1224
Query: 779 RDQAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAE 838
+RC+ F+ + + E F K + + H + L+ + + +
Sbjct: 1225 ---------QRCTAFDAEQQQFW---EQFHKEAPFRFDSI-HPHQMLDARHIEIQQMEST 1271
Query: 839 FELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQ 898
I++ L E Y L+ K ++LW T + W P +N E
Sbjct: 1272 MASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEA 1331
Query: 899 IAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQ 958
+ E R L K + A L V + + + NP +++RHW+
Sbjct: 1332 MELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQ----NPAIRERHWR 1387
Query: 959 QISEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNV 1018
Q+ + G + T L+++L+ + +++ I A+KE +EK L ++ W +
Sbjct: 1388 QLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGM 1447
Query: 1019 TFSFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQD 1078
F + + T+ +LC+ +D+ +L+D+ ++ Q + S ++ E W++KL +
Sbjct: 1448 EFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDA 1507
Query: 1079 NLDAWLKCQATWLYLEPIFS-SEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAA 1137
+ W + Q TW +LE IF+ SEDI AQ+P++ ++F +D +K L A K ++
Sbjct: 1508 VISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTT 1567
Query: 1138 DQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQP 1197
++P + EKL++ L +K L +YL+ KRL FPRF+FLS+ +LL+ILS P +VQ
Sbjct: 1568 NKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQR 1627
Query: 1198 HLKKCFEGIAKLEFTDNLE------IVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVE 1251
HL K F+ +AK+ F + +GM S E+E V F + P + G VE WL V
Sbjct: 1628 HLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSE---PCDCSGQVEIWLNHVL 1684
Query: 1252 QMMLASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALA------EN 1305
M A++R + G+ AY + PR W+ P QV + + I+WT EV A A E+
Sbjct: 1685 GHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYES 1744
Query: 1306 TLLDFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDF 1365
+ D+ KK Q+ ++ ++ G+LS G R + + IDVHARDVVAK+ +V + F
Sbjct: 1745 AMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAF 1804
Query: 1366 QWISQLRYYW--VAKDVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNL 1423
W+SQLR+ W K I + LY YEYLGN+PRLVITPLTDRCY TL +L L +
Sbjct: 1805 LWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTM 1864
Query: 1424 GGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEF 1483
GAP GPAGTGKTETTKDL +AL VFNCS+ +DYK+ G +KGLAQ GAW CFDEF
Sbjct: 1865 SGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEF 1924
Query: 1484 NRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPD 1543
NRI VEVLSVVA Q+ SIQ AI K + F F G E+SLNP+ +FITMNPGYAGR ELP+
Sbjct: 1925 NRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPE 1984
Query: 1544 NLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGM 1603
NLK+LFR AM+VPD+ LI EI L + GF++++SLA+K + Y+LC E LS Q HYD+G+
Sbjct: 1985 NLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGL 2044
Query: 1604 RAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLP 1663
RA+KSVL AG+LK P+ E +L+R+L D N+ K + D+P+F G+I DLFP + +P
Sbjct: 2045 RAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVP 2104
Query: 1664 KPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVL 1723
+ F ++ I +KLQ F+ K++Q+ E++ VRH +VG GK+
Sbjct: 2105 RRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQ----- 2159
Query: 1724 AAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSL 1783
L LH Q+ + + +NPKA+T +L+G + + EW DG+ ++ RE A+
Sbjct: 2160 --VLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANIT 2217
Query: 1784 SDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPA 1843
D KWI+ DG +D +WIE++NTV+DDNK L L S E I +N M L+FE + L A+PA
Sbjct: 2218 HDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPA 2277
Query: 1844 TVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCK 1903
TVSR G++Y+ P LGW P S+++ + + ++ D ++ CL+ R K
Sbjct: 2278 TVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYL---PTCLDTLRTRFK 2334
Query: 1904 FVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTV 1963
++ PI SM+++ LL+ + E+ + + + + F+F+ +W
Sbjct: 2335 KII---PIP-EQSMVQMVCHLLECLLTTEDIPADCPKEI--------YEHYFVFAAIWAF 2382
Query: 1964 AGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHW 2023
G + D + F + K+VK FP +G+I+D Y+I + +
Sbjct: 2383 GGAMVQDQLVDYRAEFSKWWL------TEFKTVK------FPSQGTIFD-YYIDPETKKF 2429
Query: 2024 ETWTQYITKEE--EKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKS 2081
E W++ + + E ++P A ++ T ET R +F++ + + P++ VG GTGKS
Sbjct: 2430 EPWSKLVPQFEFDPEMPLQA----CLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKS 2485
Query: 2082 AITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVD 2141
+ L L YL + F+ T++ Q ++ L+++ +GPP KK + F+D
Sbjct: 2486 VLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFID 2545
Query: 2142 DLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITG 2201
D+NMP + YG P ++RQ +D+G+W+D+ + +I ++ V+ M P G I
Sbjct: 2546 DMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTAGSFT-INP 2604
Query: 2202 RFTRHLNIISINAFEDDILTKIFSSIVDWHFGKG-FDVMFLRYGKMLVQATKTIYRDAVE 2260
R RH ++ ++ D L+ I+S I+ H G F + L+ ++
Sbjct: 2605 RLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIAT 2664
Query: 2261 NFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKED 2320
FLPT K HY+FNLRDF+ + QG+L ++ IRL++HE RV+ D++++++D
Sbjct: 2665 TFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKD 2724
Query: 2321 RQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEIT 2380
F++ + + K+T + + P + N+ F +P+ Y +
Sbjct: 2725 ----FDLFDKIQTEVLKKTFDDI---EDPVEQTQSPNLYCHFANGIGEPK-----YMPVQ 2772
Query: 2381 DLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGR 2440
+ LT + LE N ++ M LV+F A+ H+ I R+L+ +G+ LLVG+GGSG+
Sbjct: 2773 SWELLTQTLVEALENHNEVNTV-MDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGK 2831
Query: 2441 QSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDES 2500
QS +L+ F+++ +++QI + K Y D++ DL + L+ GV +TVFL D Q+ DE
Sbjct: 2832 QSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADER 2891
Query: 2501 FVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKI 2560
F+ IN LL +G++P+++ DE +I+ ++ ++QG + + + FFI+R+ ++
Sbjct: 2892 FLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQG--LVDNRENCWKFFIDRIRRQL 2949
Query: 2561 SFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVE-LDDNIRV 2619
+L SP+G+ R R R FP+++NC I WF WP ALE V+ +FL++ E ++ ++
Sbjct: 2950 KVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQ 3009
Query: 2620 EVVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRY 2679
+ + SV + S Y + +R+NY TP S+LE I +++LL+ R+E+ R
Sbjct: 3010 SISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERL 3069
Query: 2680 LTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADE 2739
GL KL ++QV ++ +L A + +L +E+ K++ + ET + +K + +E
Sbjct: 3070 ENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEE 3129
Query: 2740 KEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVM 2799
++ V + + +CE DLA+A PAL AA AAL+TLN +++ +KS +PP V V
Sbjct: 3130 QKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVS 3189
Query: 2800 ESICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDLK-FLESLKTYDKDNIPPLTMKR 2858
++ ++ + D S W +K + + FL+SL ++K+NI +K
Sbjct: 3190 AAVMVLMAPRGRVPKDRS---------WKAAKVTMAKVDGFLDSLINFNKENIHENCLKA 3240
Query: 2859 IRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQ 2918
IR ++ PEF P + S A GLC WV + + V V PKR+ L +A L A
Sbjct: 3241 IRP-YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAA 3299
Query: 2919 MQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEK 2978
+KL +A++ + + L L FE+ K ++ E+ + + A +L+ GL E
Sbjct: 3300 QEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASEN 3359
Query: 2979 DRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQ----WLAECKDKVIP 3034
RW +A + + L GD+LL + ++YLG FT YR ++ +L++ K IP
Sbjct: 3360 VRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTP-IP 3418
Query: 3035 GFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKN 3094
L D + AWQ GLP D S++N I+ N RW LM+DP Q KWIKN
Sbjct: 3419 VTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKN 3478
Query: 3095 MEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEY 3154
+ L V + Y++++E AL+ G VLIEN+ E +D + P+L + K+ +
Sbjct: 3479 -KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG--RF 3535
Query: 3155 MRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEK 3214
+++G+ EY+ F+L + T+L NPHY PE+ + L+NF +T GL+DQLL V + E+
Sbjct: 3536 IKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMER 3595
Query: 3215 PELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEIS 3274
P+LE+ K+ L + K LK +ED +L LS + GN L + ++ L +K + E+
Sbjct: 3596 PDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVE 3655
Query: 3275 EKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLT 3334
+K + A +TE +I+E R Y+P A ++ ++F ++DL+ I PMYQ+SL F ++ ++
Sbjct: 3656 KKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVE 3715
Query: 3335 HSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWY 3394
+ E L R+ +ID T S+Y R LFE DKL + LT I+ +E+
Sbjct: 3716 RAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELD 3775
Query: 3395 FLLTGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAW 3454
FLL + P ++LS +AW + S++ + L +E + WK +S
Sbjct: 3776 FLLRSPVQTGTASP---VEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESEC 3832
Query: 3455 PHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYND 3514
P +E+LP WK L+++ +LR +RPD+M A+R+F+ E +G Y+ D S+ +
Sbjct: 3833 PEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEE 3892
Query: 3515 SSCCAPLIFVLSPSADPMAGLLKFADDLG--MGGTRTQTISLGQGQGPIAAKMINNAIKD 3572
S P+ F+LSP DP+ + LG +SLGQGQ +A ++ A K
Sbjct: 3893 SGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKK 3952
Query: 3573 GTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEK-----FPVSILQN 3627
G WV+LQN HL A W+ TLEK EE E+++ FR+++++ P+ P IL+N
Sbjct: 3953 GHWVILQNIHLVAKWLSTLEKKLEE--HSENSHPEFRVFMSAEPAPSPEGHIIPQGILEN 4010
Query: 3628 GIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNF 3687
IK+TNEPP G+ ANL ++ L++ D + + C++ ++ +LF LC+FHAVV ERR F
Sbjct: 4011 SIKITNEPPTGMHANLHKA-LDNFTQDTL--EMCSRETEFKSILFALCYFHAVVAERRKF 4067
Query: 3688 GPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLL 3747
GP GWN Y FN DL IS+ + FL +VP+D L YL GE YGG +TDD DRRL
Sbjct: 4068 GPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLC 4127
Query: 3748 LSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADI 3807
+ L F E+ E SLAPG + +P + Y Y Y+ P ++GLH NA+I
Sbjct: 4128 RTYLGEFIRPEMLEGELSLAPG--FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEI 4185
Query: 3808 TKDNQETNQLFEGVLLTLPRQS---GGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLY 3864
Q + +LF VL PR S G+G + +E V+ L ++IL ++ +F++ E+M
Sbjct: 4186 GFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMA-- 4243
Query: 3865 PVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVP 3924
V V QE R N LT+ ++RSL L +KG++ M+S +E + N++ VP
Sbjct: 4244 KVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVP 4303
Query: 3925 AMWAAKSYPSLKPLGGYVADLLARLTFFQEWI-DKGPPVVFWISGFYFTQSFLTGVSQNY 3983
WA ++YPS L + DLL R+ + W D P W++GF+ QSFLT + Q+
Sbjct: 4304 ESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQST 4363
Query: 3984 ARKYTIPIDHIGFEFEVTPQ-ETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKIL 4042
ARK P+D + + ++T + + P +GAYI GLF+EGA WD + I E+ K L
Sbjct: 4364 ARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDL 4423
Query: 4043 YDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKH 4102
P+P++++K + + +Y CPVYKTS R T YV + L T
Sbjct: 4424 TPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPT---------YVWTFNLKTKENPSK 4474
Query: 4103 WINRGVASLCQL 4114
W+ GVA L Q+
Sbjct: 4475 WVLAGVALLLQI 4486
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1894 bits (4906), Expect = 0.0
Identities = 1171/3414 (34%), Positives = 1805/3414 (52%), Gaps = 213/3414 (6%)
Query: 786 LIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAF---AEFELI 842
L ++C +FEL+ H E FR+ + + K+LN+ F E +
Sbjct: 1200 LRRKCQQFELK---QHEFRERFRREAPFSFSDPNPY--------KSLNKVFLLKGIMEAL 1248
Query: 843 NKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEE 902
+K L E Y L+A + ++LW + E+W +N EQ+ +
Sbjct: 1249 SKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDID 1308
Query: 903 IGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISE 962
+ L K + A L VK I + +S NP +++RHWQQ+ +
Sbjct: 1309 CKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPAIRERHWQQLMQ 1364
Query: 963 IVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSF 1022
+ K +E T L+++L+ + +++ I A KE +EK L + W + F
Sbjct: 1365 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1424
Query: 1023 VKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDA 1082
+ T T +L + + + L+D+ ++ Q + S ++ E W++KL +
Sbjct: 1425 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1484
Query: 1083 WLKCQATWLYLEPIF-SSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPR 1141
W + Q TW +LE IF SEDI Q+P + ++F ++ +K+LM AVK ++ A +P
Sbjct: 1485 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1544
Query: 1142 MAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKK 1201
+ KL+ L +K L +YLE KRL FPRF+F+S+ +LL+ILS DP+ V HL K
Sbjct: 1545 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1604
Query: 1202 CFEGIAKLEFTDN-----LEI-VGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMML 1255
F+ + KL+F + L++ +GM S E E + F Q+ + G VE WL +V M
Sbjct: 1605 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQE---CDLSGQVEVWLNRVLDRMC 1661
Query: 1256 ASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALA------ENTLLD 1309
+++R I + Y + PR W+L +P Q I+WT EV A A EN + D
Sbjct: 1662 STLRHEIPEAVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIRD 1714
Query: 1310 FLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWIS 1369
+ KK Q+ ++ L+ G L++G R+ + + IDVHARDVVAK+ V F W +
Sbjct: 1715 YNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQA 1771
Query: 1370 QLRYYW--VAKDVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAP 1427
QLR+ W + I + Y YEYLGN+PRLVITPLTDRCY TL +L L +GGAP
Sbjct: 1772 QLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAP 1831
Query: 1428 EGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIE 1487
GPAGTGKTETTKDL +AL VFNCS+ +DYK+ G +KGLAQ GAW CFDEFNRI
Sbjct: 1832 AGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRIS 1891
Query: 1488 VEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKA 1547
VEVLSV+A Q+ +Q AI K K F F G + L PT +FITMNPGYAGRAELP+NLKA
Sbjct: 1892 VEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKA 1951
Query: 1548 LFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVK 1607
LFR AM+VPD+ LI EI L + GFL++R LA+K + Y LC E LS Q HYD+G+RA+K
Sbjct: 1952 LFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIK 2011
Query: 1608 SVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDY 1667
SVL AG+LK P E +L+RAL D N+ K + D+P+F G+I DLFP + +P+
Sbjct: 2012 SVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRD 2071
Query: 1668 EVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAAL 1727
F K++ +I ++KLQ F+ K++Q+ E++ VRH IVG+ GK+ K L
Sbjct: 2072 LNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTY 2131
Query: 1728 GDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDR 1787
+L + + AV+ ++PKA+T +L+G + V+ EW DG+ + R+ A+ D
Sbjct: 2132 QNL----KRKPVAVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGP 2184
Query: 1788 KWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSR 1847
KWII DG +D +WIE++NTV+DDNK L L S E I +N M L+FE + L A+PATVSR
Sbjct: 2185 KWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSR 2244
Query: 1848 CGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQ 1907
G++Y+ P LGW P+ S+++ K + ++ D ++ CL+ R K +
Sbjct: 2245 AGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYL---PTCLDKLRFGFKKITP 2301
Query: 1908 TSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTI 1967
I + +++ L LL E + EL E F+F+ W G +
Sbjct: 2302 VPEITVIQTILYLLECLLTEKTVPPDSPRELYE------------LYFVFTCFWAFGGAM 2349
Query: 1968 NADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWT 2027
D + V F + K++K FP +G+I+D Y+I + + WT
Sbjct: 2350 FQDQLVDYRVEFSKWWIN------EFKTIK------FPSQGTIFD-YYIDPDTKKFLPWT 2396
Query: 2028 QYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNF 2087
+ E + + ++ T ET R +F+ ++ P++ VG GTGKS + +
Sbjct: 2397 DKVPSFE--LDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDK 2454
Query: 2088 LLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPA 2147
L L + YL + F+ T++ Q ++ L+++ +GPP KK V F+DD+NMP
Sbjct: 2455 LESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPE 2514
Query: 2148 KEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHL 2207
+ YG P L+RQ +DH +W+D+ T DI + V M P G I R RH
Sbjct: 2515 VDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHF 2573
Query: 2208 NIISINAFEDDILTKIFSSIVDWHFG-KGFDVMFLRYGKMLVQATKTIYRDAVENFLPTP 2266
+ +++ + LT I+++I+ H + + R LV A +++ FLPT
Sbjct: 2574 CVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTA 2633
Query: 2267 SKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFN 2326
K HYVFNLRD S + QG+L L+ +RLW+HE RV+ D+++D++D++
Sbjct: 2634 IKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHR 2693
Query: 2327 MVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLT 2386
+ +T F +++L + F + + D K Y +TD+ L
Sbjct: 2694 VTMASTKKFFDDLGDELLF------------AKPNIFCHFAQGIGDPK-YVPVTDMAPLN 2740
Query: 2387 VVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKL 2446
++ L+ +N ++ A M+LV+F A+ HI RI R+L+ +G+ LLVG+GGSG+QS ++L
Sbjct: 2741 KLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRL 2799
Query: 2447 STFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDIN 2506
+ +++ +++QI + K Y D + DL ++ V +VFL D+Q+ +E F+ IN
Sbjct: 2800 AAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIN 2859
Query: 2507 MLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAM 2566
LL +G++P +F DE +I+ M+ ++ G + T + + FFIE+V ++ L
Sbjct: 2860 DLLASGEIPGLFMEDEVENIISSMRPQVKSLG--MNDTRETCWKFFIEKVRRQLKVILCF 2917
Query: 2567 SPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVE-LDDNIRVEVVSMC 2625
SP+G R R R FP+++NC IDWF WP DAL V+ +FLE+ E + ++ +
Sbjct: 2918 SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFM 2977
Query: 2626 KYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQK 2685
Y +V ++S Y RR+NY TP ++LE I ++ LL KR E+ R GL K
Sbjct: 2978 SYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMK 3037
Query: 2686 LDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVA 2745
L ASQV ++ +L + +L +E +++ + E + +K + +E + V
Sbjct: 3038 LQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVI 3097
Query: 2746 AAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIM 2805
+ CE DLA+A PAL AA ALDTLN +++ +KS +PP V V ++ I+
Sbjct: 3098 NKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL 3157
Query: 2806 KGMKPERKPDPSGSGKMIED-YWGVSKKILGDL-KFLESLKTYDKDNIPPLTMKRIRERF 2863
+ GK+ +D W +K ++G + FL+SLK +DK++IP +K + +
Sbjct: 3158 ----------TAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-Y 3206
Query: 2864 INHPEFQPAVIKNVSSACEGLCKW----VRAMEVYDRVAKVVAPKRERLREAEGKLAAQM 2919
+P F P I++ S+A GLC W VR EVY VAPKR+ L EA +LA
Sbjct: 3207 QGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD----VAPKRQALEEANAELAEAQ 3262
Query: 2920 QKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKD 2979
+KL++ + ++ + L L FE+ +K ++ + ++ ++ A +L+ GL E
Sbjct: 3263 EKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENI 3322
Query: 2980 RWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQ-WLAECKDKVIP---- 3034
RW E+ + L GDVLL S V+Y+G FT YR + + W+ + +P
Sbjct: 3323 RWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPIT 3382
Query: 3035 -GFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIK 3093
G SL L D + W GLP D S +N I+ N+ RW L++D Q KWIK
Sbjct: 3383 NGLDPLSL---LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIK 3439
Query: 3094 NMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVE 3153
N + ++L I+ +Y+ ++E A+ G +LIENIGE +D ++P+L + T K+ +
Sbjct: 3440 NKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--K 3496
Query: 3154 YMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKE 3213
Y+++G+ +EY F+L + T+ NPHY PE+ + L+NF++T GL+DQLL V AKE
Sbjct: 3497 YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKE 3556
Query: 3214 KPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEI 3273
+P+LE+ K L + K LKE+ED +L LS + GN L D ++ L ++K + EI
Sbjct: 3557 RPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEI 3616
Query: 3274 SEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSL 3333
EK A +TE +I+E R Y+P A ++ ++F ++DL I P+YQ+SL F ++ ++
Sbjct: 3617 EEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAI 3676
Query: 3334 THSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVW 3393
+T + E+ R+ + D T S+Y R LFE+DKL+F +T ++ KKE+
Sbjct: 3677 QRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVEL 3736
Query: 3394 YFLLTGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSA 3453
FLL P +L + W I S + + L +E + WK + +S
Sbjct: 3737 DFLLRFPFKAGVVSP---VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESE 3793
Query: 3454 WPHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYN 3513
P +E P WK L+K+ ++RCLRPD+M A++ F+ E MG ++E + + SY
Sbjct: 3794 APEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYE 3853
Query: 3514 DSSCCAPLIFVLSPSADPMAGLLKFADDLG--MGGTRTQTISLGQGQGPIAAKMINNAIK 3571
+SS + F+LSP DP+ + LG + + +SLGQGQ +A ++ A +
Sbjct: 3854 ESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAE 3913
Query: 3572 DGTWVVLQ--------NCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEK---- 3619
G WV+LQ N HL A W+ TL+K E ++ +R+++++ P+
Sbjct: 3914 KGHWVILQVRGGQHCRNIHLVARWLGTLDKKLEH--YSTGSHEDYRVFISAEPAPSPETH 3971
Query: 3620 -FPVSILQNGIKMTNEPPKGLRANL---LRSYLNDPISDPVFFQSCAKAVMWQKMLFGLC 3675
P IL+N IK+TNEPP G+ ANL L + D + + C K + ++ MLF LC
Sbjct: 3972 IIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTL------EMCTKEMEFKCMLFALC 4025
Query: 3676 FFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYG 3735
+FHAVV ERR FG GWN Y FN DL IS+ + +L +VP+D L YL GE YG
Sbjct: 4026 YFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYG 4085
Query: 3736 GRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYL-RNLPITA 3794
G +TDD DRRL + L+ + E+ E LAPG + IPP+ Y+ Y +Y+ NLP
Sbjct: 4086 GHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG--FQIPPNLDYKGYHEYIDENLP-PE 4142
Query: 3795 HPEVFGLHENADITKDNQETNQLFEGVLLTLPRQS---GGSGKSPQE------------- 3838
P ++GLH NA+I + +LF VL P+++ G+G S +E
Sbjct: 4143 SPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERK 4202
Query: 3839 ----------------VVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIR 3882
V+ + DIL K+P F++ E+M + V QE R
Sbjct: 4203 GEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMA--KAAEKTPYVVVAFQECER 4260
Query: 3883 FNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYV 3942
N LT +RRSL L +KG++ +++++E++ ++ VP W A++YPS+ L +
Sbjct: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320
Query: 3943 ADLLARLTFFQEW-IDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVT 4001
ADLL R+ + W D P W++GF+ QSFLT + Q+ ARK P+D + EVT
Sbjct: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380
Query: 4002 PQETV-MENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFL 4060
+ M P +G+Y+ GLF+EGARWD +T I E+ K L +P+I++K
Sbjct: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440
Query: 4061 HQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQL 4114
++IY CPVYKT R T YV + L T WI VA L Q+
Sbjct: 4441 TKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1893 bits (4904), Expect = 0.0
Identities = 1171/3414 (34%), Positives = 1805/3414 (52%), Gaps = 213/3414 (6%)
Query: 786 LIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAF---AEFELI 842
L ++C +FEL+ H E FR+ + + K+LN+ F E +
Sbjct: 1200 LRRKCQQFELK---QHEFRERFRREAPFSFSDPNPY--------KSLNKVFLLKGIMEAL 1248
Query: 843 NKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEE 902
+K L E Y L+A + ++LW + E+W +N EQ+ +
Sbjct: 1249 SKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDID 1308
Query: 903 IGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISE 962
+ L K + A L VK I + +S NP +++RHWQQ+ +
Sbjct: 1309 CKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPAIRERHWQQLMQ 1364
Query: 963 IVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSF 1022
+ K +E T L+++L+ + +++ I A KE +EK L + W + F
Sbjct: 1365 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1424
Query: 1023 VKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDA 1082
+ T T +L + + + L+D+ ++ Q + S ++ E W++KL +
Sbjct: 1425 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1484
Query: 1083 WLKCQATWLYLEPIF-SSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPR 1141
W + Q TW +LE IF SEDI Q+P + ++F ++ +K+LM AVK ++ A +P
Sbjct: 1485 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1544
Query: 1142 MAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKK 1201
+ KL+ L +K L +YLE KRL FPRF+F+S+ +LL+ILS DP+ V HL K
Sbjct: 1545 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1604
Query: 1202 CFEGIAKLEFTDN-----LEI-VGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMML 1255
F+ + KL+F + L++ +GM S E E + F Q+ + G VE WL +V M
Sbjct: 1605 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQE---CDLSGQVEVWLNRVLDRMC 1661
Query: 1256 ASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALA------ENTLLD 1309
+++R I + Y + PR W+L +P Q I+WT EV A A EN + D
Sbjct: 1662 STLRHEIPEAVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKD 1714
Query: 1310 FLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWIS 1369
+ KK Q+ ++ L+ G L++G R+ + + IDVHARDVVAK+ V F W +
Sbjct: 1715 YNKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQA 1771
Query: 1370 QLRYYW--VAKDVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAP 1427
QLR+ W + I + Y YEYLGN+PRLVITPLTDRCY TL +L L +GGAP
Sbjct: 1772 QLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAP 1831
Query: 1428 EGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIE 1487
GPAGTGKTETTKDL +AL VFNCS+ +DYK+ G +KGLAQ GAW CFDEFNRI
Sbjct: 1832 AGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRIS 1891
Query: 1488 VEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKA 1547
VEVLSV+A Q+ +Q AI K K F F G + L PT +FITMNPGYAGRAELP+NLKA
Sbjct: 1892 VEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKA 1951
Query: 1548 LFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVK 1607
LFR AM+VPD+ LI EI L + GFL++R LA+K + Y LC E LS Q HYD+G+RA+K
Sbjct: 1952 LFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIK 2011
Query: 1608 SVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDY 1667
SVL AG+LK P E +L+RAL D N+ K + D+P+F G+I DLFP + +P+
Sbjct: 2012 SVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRD 2071
Query: 1668 EVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAAL 1727
F K++ +I ++KLQ F+ K++Q+ E++ VRH IVG+ GK+ K L
Sbjct: 2072 LNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTY 2131
Query: 1728 GDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDR 1787
+L + + AV+ ++PKA+T +L+G + V+ EW DG+ + R+ A+ D
Sbjct: 2132 QNL----KRKPVAVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGP 2184
Query: 1788 KWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSR 1847
KWII DG +D +WIE++NTV+DDNK L L S E I +N M L+FE + L A+PATVSR
Sbjct: 2185 KWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSR 2244
Query: 1848 CGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQ 1907
G++Y+ P LGW P+ S+++ K + ++ D ++ CL+ R K +
Sbjct: 2245 AGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYL---PTCLDKLRFGFKKITP 2301
Query: 1908 TSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTI 1967
I + +++ L LL E + EL E F+F+ W G +
Sbjct: 2302 VPEITVIQTILYLLECLLTEKTVPPDSPRELYE------------LYFVFTCFWAFGGAM 2349
Query: 1968 NADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWT 2027
D + V F + K++K FP +G+I+D Y+I + + WT
Sbjct: 2350 FQDQLVDYRVEFSKWWIN------EFKTIK------FPSQGTIFD-YYIDPDTKKFLPWT 2396
Query: 2028 QYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNF 2087
+ E + + ++ T ET R +F+ ++ P++ VG GTGKS + +
Sbjct: 2397 DKVPSFE--LDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDK 2454
Query: 2088 LLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPA 2147
L L + YL + F+ T++ Q ++ L+++ +GPP KK V F+DD+NMP
Sbjct: 2455 LESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPE 2514
Query: 2148 KEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHL 2207
+ YG P L+RQ +DH +W+D+ T DI + V M P G I R RH
Sbjct: 2515 VDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHF 2573
Query: 2208 NIISINAFEDDILTKIFSSIVDWHFG-KGFDVMFLRYGKMLVQATKTIYRDAVENFLPTP 2266
+ +++ + LT I+++I+ H + + R LV A +++ FLPT
Sbjct: 2574 CVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTA 2633
Query: 2267 SKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFN 2326
K HYVFNLRD S + QG+L L+ +RLW+HE RV+ D+++D++D++
Sbjct: 2634 IKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHR 2693
Query: 2327 MVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLT 2386
+ +T F +++L + F + + D K Y +TD+ L
Sbjct: 2694 VTMASTKKFFDDLGDELLF------------AKPNIFCHFAQGIGDPK-YVPVTDMAPLN 2740
Query: 2387 VVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKL 2446
++ L+ +N ++ A M+LV+F A+ HI RI R+L+ +G+ LLVG+GGSG+QS ++L
Sbjct: 2741 KLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRL 2799
Query: 2447 STFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDIN 2506
+ +++ +++QI + K Y D + DL ++ V +VFL D+Q+ +E F+ IN
Sbjct: 2800 AAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIN 2859
Query: 2507 MLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAM 2566
LL +G++P +F DE +I+ M+ ++ G + T + + FFIE+V ++ L
Sbjct: 2860 DLLASGEIPGLFMEDEVENIISSMRPQVKSLG--MNDTRETCWKFFIEKVRRQLKVILCF 2917
Query: 2567 SPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVE-LDDNIRVEVVSMC 2625
SP+G R R R FP+++NC IDWF WP DAL V+ +FLE+ E + ++ +
Sbjct: 2918 SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFM 2977
Query: 2626 KYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQK 2685
Y +V ++S Y RR+NY TP ++LE I ++ LL KR E+ R GL K
Sbjct: 2978 SYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMK 3037
Query: 2686 LDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVA 2745
L ASQV ++ +L + +L +E +++ + E + +K + +E + V
Sbjct: 3038 LQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVI 3097
Query: 2746 AAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIM 2805
+ CE DLA+A PAL AA ALDTLN +++ +KS +PP V V ++ I+
Sbjct: 3098 NKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL 3157
Query: 2806 KGMKPERKPDPSGSGKMIED-YWGVSKKILGDL-KFLESLKTYDKDNIPPLTMKRIRERF 2863
+ GK+ +D W +K ++G + FL+SLK +DK++IP +K + +
Sbjct: 3158 ----------TAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-Y 3206
Query: 2864 INHPEFQPAVIKNVSSACEGLCKW----VRAMEVYDRVAKVVAPKRERLREAEGKLAAQM 2919
+P F P I++ S+A GLC W VR EVY VAPKR+ L EA +LA
Sbjct: 3207 QGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD----VAPKRQALEEANAELAEAQ 3262
Query: 2920 QKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKD 2979
+KL++ + ++ + L L FE+ +K ++ + ++ ++ A +L+ GL E
Sbjct: 3263 EKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENI 3322
Query: 2980 RWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQ-WLAECKDKVIP---- 3034
RW E+ + L GDVLL S V+Y+G FT YR + + W+ + +P
Sbjct: 3323 RWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPIT 3382
Query: 3035 -GFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIK 3093
G SL L D + W GLP D S +N I+ N+ RW L++D Q KWIK
Sbjct: 3383 NGLDPLSL---LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIK 3439
Query: 3094 NMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVE 3153
N + ++L I+ +Y+ ++E A+ G +LIENIGE +D ++P+L + T K+ +
Sbjct: 3440 NKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--K 3496
Query: 3154 YMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKE 3213
Y+++G+ +EY F+L + T+ NPHY PE+ + L+NF++T GL+DQLL V AKE
Sbjct: 3497 YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKE 3556
Query: 3214 KPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEI 3273
+P+LE+ K L + K LKE+ED +L LS + GN L D ++ L ++K + EI
Sbjct: 3557 RPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEI 3616
Query: 3274 SEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSL 3333
EK A +TE +I+E R Y+P A ++ ++F ++DL I P+YQ+SL F ++ ++
Sbjct: 3617 EEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAI 3676
Query: 3334 THSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVW 3393
+T + E+ R+ + D T S+Y R LFE+DKL+F +T ++ KKE+
Sbjct: 3677 QRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVEL 3736
Query: 3394 YFLLTGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSA 3453
FLL P +L + W I S + + L +E + WK + +S
Sbjct: 3737 DFLLRFPFKAGVVSP---VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESE 3793
Query: 3454 WPHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYN 3513
P +E P WK L+K+ ++RCLRPD+M A++ F+ E MG ++E + + SY
Sbjct: 3794 APEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYE 3853
Query: 3514 DSSCCAPLIFVLSPSADPMAGLLKFADDLG--MGGTRTQTISLGQGQGPIAAKMINNAIK 3571
+SS + F+LSP DP+ + LG + + +SLGQGQ +A ++ A +
Sbjct: 3854 ESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAE 3913
Query: 3572 DGTWVVLQ--------NCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEK---- 3619
G WV+LQ N HL A W+ TL+K E ++ +R+++++ P+
Sbjct: 3914 KGHWVILQVRGGQHCRNIHLVARWLGTLDKKLER--YSTGSHEDYRVFISAEPAPSPETH 3971
Query: 3620 -FPVSILQNGIKMTNEPPKGLRANL---LRSYLNDPISDPVFFQSCAKAVMWQKMLFGLC 3675
P IL+N IK+TNEPP G+ ANL L + D + + C K + ++ MLF LC
Sbjct: 3972 IIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTL------EMCTKEMEFKCMLFALC 4025
Query: 3676 FFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYG 3735
+FHAVV ERR FG GWN Y FN DL IS+ + +L +VP+D L YL GE YG
Sbjct: 4026 YFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYG 4085
Query: 3736 GRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYL-RNLPITA 3794
G +TDD DRRL + L+ + E+ E LAPG + IPP+ Y+ Y +Y+ NLP
Sbjct: 4086 GHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG--FQIPPNLDYKGYHEYIDENLP-PE 4142
Query: 3795 HPEVFGLHENADITKDNQETNQLFEGVLLTLPRQS---GGSGKSPQE------------- 3838
P ++GLH NA+I + +LF VL P+++ G+G S +E
Sbjct: 4143 SPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERK 4202
Query: 3839 ----------------VVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIR 3882
V+ + DIL K+P F++ E+M + V QE R
Sbjct: 4203 GEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMA--KAAEKTPYVVVAFQECER 4260
Query: 3883 FNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYV 3942
N LT +RRSL L +KG++ +++++E++ ++ VP W A++YPS+ L +
Sbjct: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320
Query: 3943 ADLLARLTFFQEW-IDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVT 4001
ADLL R+ + W D P W++GF+ QSFLT + Q+ ARK P+D + EVT
Sbjct: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380
Query: 4002 PQETV-MENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFL 4060
+ M P +G+Y+ GLF+EGARWD +T I E+ K L +P+I++K
Sbjct: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440
Query: 4061 HQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQL 4114
++IY CPVYKT R T YV + L T WI VA L Q+
Sbjct: 4441 TKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 1869 bits (4842), Expect = 0.0
Identities = 1152/3338 (34%), Positives = 1765/3338 (52%), Gaps = 153/3338 (4%)
Query: 832 LNRAFAEFELINKEEELLEKEKST---------YPLLQAMLKNKVPYEQLWSTAYEFSIK 882
L++A E E + EEE+L+ ++ST Y ++ K + LW
Sbjct: 1282 LDKANEELEAL--EEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRS 1339
Query: 883 SEEWMNGPLFLLNAEQIAEEIGNMWRTT-----YKLIKTLSDVPAPRRLAENVKIKIDKF 937
+ W ++ EQ+ E+ + + + L K + A L VK
Sbjct: 1340 IDNWTKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASL 1399
Query: 938 KQYIPILSISCNPGMKDRHWQQISEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAA 997
+ + S P ++DRHW Q+ + +G + E T L+++L + + + I
Sbjct: 1400 RAITELQS----PALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDK 1455
Query: 998 ASKEYSLEKNLDRMKLDWVNVTFSFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSP 1057
A KE EK + + W + FS+ + T +L + + + L+ + ++ QT+ S
Sbjct: 1456 AVKELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSK 1515
Query: 1058 FIKPIEAECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIF-SSEDIIAQMPEEGRKFGIV 1116
+++ + W+ KL + W++ Q TW +LE IF SEDI Q+ ++ R+F V
Sbjct: 1516 YVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGV 1575
Query: 1117 DSYWKSLMSQAVKDNRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFF 1176
D+ +K LM + K +L A +P + EKL++ L +K L +YLE KR+ FPRF+F
Sbjct: 1576 DAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYF 1635
Query: 1177 LSNDELLEILSETKDPLRVQPHLKKCFEGIAKLEFTDNLEI-----VGMISSEKETVPFI 1231
+S+ +LL+ILS+ P +V HL K F+ IA L+F DN ++ VGM S EKE VPF
Sbjct: 1636 VSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQ 1695
Query: 1232 QKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSS 1291
+ G VE WL Q+EQ M ++R I I AY + PR W+ +P QV + S
Sbjct: 1696 AE---CECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQ 1752
Query: 1292 IFWTQEVSQALA------ENTLLDFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDV 1345
I+WT +V A + E L DF KK Q+ ++ L+ G+L G R + + IDV
Sbjct: 1753 IWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDV 1812
Query: 1346 HARDVVAKLSEDR--VSDLNDFQWISQLRYYW--VAKDVQVQIITTEALYGYEYLGNSPR 1401
HARDVVAKL + V F W+SQLR+ W K V I + Y YEYLGNSPR
Sbjct: 1813 HARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPR 1872
Query: 1402 LVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDY 1461
LVITPLTDRCY TL +L L + GAP GPAGTGKTETTKDL +AL VFNCS+ +DY
Sbjct: 1873 LVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDY 1932
Query: 1462 KAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSL 1521
K++G +KGL Q GAW CFDEFNRI VEVLSVVA Q+ I AI + K F+F G ++L
Sbjct: 1933 KSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITL 1992
Query: 1522 NPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQK 1581
P+ +FITMNPGYAGR ELP+NLKALFR AM+ PD LI EI L + GF+D+R+LA+K
Sbjct: 1993 KPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARK 2052
Query: 1582 IVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKF 1641
+ Y LC E LS Q HYD+G+RA+KSVL AG+LK E +L+RAL D N+ K
Sbjct: 2053 FITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKI 2112
Query: 1642 LAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMML 1701
+ D+P+F G++ DLFP + +P+ F +++ + +++LQP FI K++Q+ E++
Sbjct: 2113 VTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLA 2172
Query: 1702 VRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFD 1761
VRH +VG+ GK+ + L + M++ V + +NPKA+T +L+G
Sbjct: 2173 VRHSVFVVGNAGTGKSKILRTLNRTYVN------MKQKPV-WNDLNPKAVTTDELFGFIH 2225
Query: 1762 QVSHEWMD---------GVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNK 1812
+ EW D G+ ++ REQA+ D KWI+ DG +D +WIE++NTV+DDNK
Sbjct: 2226 HATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNK 2285
Query: 1813 KLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLP 1872
L L S E I + M L+FE L A+PATVSR G++Y+ P LGW P S++D
Sbjct: 2286 VLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRR 2345
Query: 1873 SSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVE 1932
K + ++ D + V CL+ R K + L ++ L LL
Sbjct: 2346 HQSEKANLTILFDKY---VPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENVPS 2402
Query: 1933 EEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPR 1992
+ E+ E F+F+ +W GT+ D + F
Sbjct: 2403 DSPKEVYE------------VYFVFACIWAFGGTLLQDQISDYQADFSRWWQ-------- 2442
Query: 1993 PKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTME 2052
K +K K FP +G+I+D Y++ + W I + + + +++ T E
Sbjct: 2443 -KEMKAVK---FPSQGTIFD-YYVDHKTKKLLPWADKIA--QFTMDPDVPLQTVLVHTTE 2495
Query: 2053 TARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNCINFSARTSANQT 2112
TAR +F++ L+ P++ VG G GK+ + L L ++ Y+ + + F+ T++
Sbjct: 2496 TARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-YIVSRVPFNYYTTSTAL 2554
Query: 2113 QDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDK 2172
Q I+ L+++ +GP KK + F+DD+NMP ++YG P L+RQ ID+G+W+D+
Sbjct: 2555 QKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDR 2614
Query: 2173 KDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHF 2232
+ +I + V M P G I R RH + + N D L I+ I +HF
Sbjct: 2615 QKVMLKEIHNCQYVACMNPMVGSFT-INPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHF 2673
Query: 2233 -GKGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHT 2291
+ F LR G L+QAT ++ + NFLPT K HY+FNLRD S V QG+L
Sbjct: 2674 QQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPE 2733
Query: 2292 HLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPTG 2351
L+ I LW+HE RV+ D+LIDK+D +F + ET F+ +L+
Sbjct: 2734 CLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQ----- 2788
Query: 2352 KIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRF 2411
+ L + +F Y + D + L ++ L+ +N ++ A M LV+F
Sbjct: 2789 -------QPLIY-CHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELN-AAMHLVLFED 2839
Query: 2412 AIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWRE 2471
A++H+ RI R+L+ +G LLVG+GGSG+QS ++L+ ++ E++QI +T+ Y + R
Sbjct: 2840 AMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRV 2899
Query: 2472 DLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQ 2531
DL + ++ G TVFL D Q+ DESF+ IN LL +G++P++F ++ I+ +
Sbjct: 2900 DLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIH 2959
Query: 2532 TAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDW 2591
G + + + + FF+ RV ++ L SP+G R R R FP+++NC IDW
Sbjct: 2960 NEVHALG--MVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDW 3017
Query: 2592 FQSWPTDALELVANKFLEDVELDDNIRVEVVSM-CKYFQESVKKLSLDYYNKLRRHNYVT 2650
F +WP +AL V+ +F+E+ + + + + +S+ + +V ++S YY RRHNY T
Sbjct: 3018 FHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTT 3077
Query: 2651 PTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILT 2710
P S+LE I FK LL K+ EV+ + R + G+QKL ASQV ++ L + + +L L
Sbjct: 3078 PKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLR 3137
Query: 2711 SEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAA 2770
+ + ++ KI +T + +K + A+E++ + ECE DL +A PAL AA
Sbjct: 3138 NHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAA 3197
Query: 2771 LAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSGKMIEDYWGVS 2830
AAL+TLN ++S +K+ NPP V V ++ ++ + D S W +
Sbjct: 3198 TAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRS---------WKAA 3248
Query: 2831 KKILGDL-KFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGLCKWVR 2889
K +G + FL++L YDK++IP +K + E ++ PEF P +I+ S A GLC WV
Sbjct: 3249 KVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVI 3308
Query: 2890 AMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTK 2949
+ + V V PKR+ L +A +LAA +KL R +L + L L FE+ +
Sbjct: 3309 NIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAE 3368
Query: 2950 KKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYL 3009
K +E + ++ + A +L+ L +K RW ++ + + L GDVLL++ V+Y+
Sbjct: 3369 KVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYV 3428
Query: 3010 GAFTVDYR---VQCQNQWLAECKDKV-IPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFS 3065
G FT YR V C +W+ + KV IP L L D I AW GLP D S
Sbjct: 3429 GPFTRQYRQELVHC--KWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMS 3486
Query: 3066 IDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTPV 3125
+N I+++ RW L+IDP Q KWIKN + L V ++ +E AL G +
Sbjct: 3487 TENAAILTHCERWPLVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNAIETALAFGDVI 3545
Query: 3126 LIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPEV 3185
LIEN+ E +D ++P+L + T K+ +Y+R+G+ E++++F+L + T+L NPHY PE+
Sbjct: 3546 LIENLEETIDPVLDPLLGRNTIKKG--KYIRIGDKECEFNKNFRLILHTKLANPHYKPEL 3603
Query: 3186 AVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILEV 3245
+ LLNF +T GL+ QLL V + E+P+LE+ K L K LK +ED +L
Sbjct: 3604 QAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLR 3663
Query: 3246 LSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIF 3305
LS ++G+ L+D ++ L ++K EI K A E +I+E R Y+PVA ++ ++
Sbjct: 3664 LSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLY 3723
Query: 3306 FCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSL 3365
F I+DL I P+YQ+SL F L+ ++ + K E++ RI +++ T +++ ++L
Sbjct: 3724 FVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQAL 3783
Query: 3366 FEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPYPNPAPQWLSEKAWAEIVR 3425
FEKDKL F + I+ +KKEI FLL +++ + +P +L+ ++W+ I
Sbjct: 3784 FEKDKLTFLSQMAFQILLRKKEIDPLELDFLLR--FTVEHTHLSPV-DFLTSQSWSAIKA 3840
Query: 3426 ASALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLRPDKMV 3485
+ + + G+ +E + +W+ +S P +E+LP WK ++K+++LR +RPD+M
Sbjct: 3841 IAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMT 3900
Query: 3486 PAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLG-- 3543
A+R F+ E +G Y+E DL ++ +SS P+ F+LSP D + L LG
Sbjct: 3901 YALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFT 3960
Query: 3544 MGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPES 3603
+ + +SLGQGQ +A + A K G WV+LQN HL A W+ TLEK+ E
Sbjct: 3961 IDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSH 4020
Query: 3604 TNARFRLWLTSYPSEK---FPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQS 3660
+ R + S P+ P +L+N IK+TNEPP G+ ANL + N D +
Sbjct: 4021 RDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYN---FDQDTLEI 4077
Query: 3661 CAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEV 3720
C+K ++ +LF LC+FHA V R FGP GW+ Y FN DL I + +L +V
Sbjct: 4078 CSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKV 4137
Query: 3721 PFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSY 3780
P++ L YL GE YGG +TDD DR+L L F + ED LAPG + PP+ Y
Sbjct: 4138 PWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPG--FAAPPYLDY 4195
Query: 3781 QSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQ--SGGS-GKSPQ 3837
Y Y+ + P ++GLH NA+I +N LF +L PR SG G+S +
Sbjct: 4196 AGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTE 4255
Query: 3838 EVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINL 3897
E V+ + DIL KLP +F++ E+M+ V QE R N L + +R SL L
Sbjct: 4256 EKVKNVLDDILEKLPEEFNMAEIMQKNS--NRSPYVLVCFQECERMNILIREIRISLEQL 4313
Query: 3898 GRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWI- 3956
++KG++ +S +E ++ VP W+ +YPS L + DLL R W
Sbjct: 4314 DLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQ 4373
Query: 3957 DKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQ-ETVMENNPEDGA 4015
D P V W+SGF+ QSFLT + Q ARK P+D +VT + + + P +GA
Sbjct: 4374 DLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGA 4433
Query: 4016 YIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSAR 4075
Y+ GLF+EGARWD + I E+ K L P+P+I+ K + Y CPVY+T R
Sbjct: 4434 YLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLR 4493
Query: 4076 RGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQ 4113
+Y+ + L ++ W+ GVA L +
Sbjct: 4494 ---------GPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 1868 bits (4838), Expect = 0.0
Identities = 1131/3317 (34%), Positives = 1794/3317 (54%), Gaps = 130/3317 (3%)
Query: 846 EELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFL-LNAEQIAEEIG 904
EEL + YP L + K ++++ T Y I++ L+ +N E+I E+
Sbjct: 1389 EELFGLPATQYPQLLEIKKQLNLLQKIY-TLYNSVIETVNSYYDILWSEVNIEKINNELL 1447
Query: 905 NMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISEIV 964
KL + L D A ++K ID F + P+L + M +RHW++I+ +
Sbjct: 1448 EFQNRCRKLPRALKDWQA----FLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTLT 1503
Query: 965 GYEIKP-TETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFV 1023
G+ + E+ L N++E K+ E++E I +A KE +E+ L ++ +W N TF+F
Sbjct: 1504 GHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFG 1563
Query: 1024 KYR---------DTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLI 1074
++ D+ + I+ ++D MLL ++ + + P +A+ +KW + L
Sbjct: 1564 SFKTRGELLLRGDSTSEIIANMEDSLMLLG-------SLLSNRYNMPFKAQIQKWVQYLS 1616
Query: 1075 RIQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRIL 1134
D +++W+ Q W+YLE +F DI Q+P+E ++F +D W +M++A + ++
Sbjct: 1617 NSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVV 1676
Query: 1135 -VAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPL 1193
+ + L LE QK L YLEKKRL FPRFFF+S+ LLEIL + D
Sbjct: 1677 QCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSH 1736
Query: 1194 RVQPHLKKCFEGIAKLEFTDNL--EIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVE 1251
+Q HL F+ I ++F + + I+ + S E ET+ + P A+G VE WL +
Sbjct: 1737 TIQAHLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDK---PVMAEGNVEVWLNSLL 1793
Query: 1252 QMMLASMREVIGLGIEAYVKVPRNHWVL-----QWPGQVVICVSSIFWTQEVSQALAENT 1306
+ +S+ VI +A + + L +P QV + + WT++ +AL N
Sbjct: 1794 EESQSSLHLVIR---QAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEAL-RNA 1849
Query: 1307 LLD--FLKKSNDQIAQI----VQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVS 1360
D ++K+N ++ + + LSS R+ L I VH RD+ L +
Sbjct: 1850 KFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIK 1909
Query: 1361 DLNDFQWISQLRYYWVAKDVQVQIITTEALYGY--EYLGNSPRLVITPLTDRCYRTLMGA 1418
DF+W+ Q R+Y+ ++ I T+ + Y E+LG + RLVITPLTDRCY TL A
Sbjct: 1910 SPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQA 1969
Query: 1419 LKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWA 1478
L +++GGAP GPAGTGKTETTKD+ + L K VVFNCSD +D++ +G+ FKGLAQ+G+W
Sbjct: 1970 LGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWG 2029
Query: 1479 CFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIF-EGTELSLNPTCAVFITMNPGYAG 1537
CFDEFNRI++ VLSV AQQI I K+FIF +G +++NP +F+TMNPGYAG
Sbjct: 2030 CFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAG 2089
Query: 1538 RAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQH 1597
R ELP+NLK FR+VAMMVPD +I + L S GF+D+ LA+K Y+LC EQLS Q
Sbjct: 2090 RQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQV 2149
Query: 1598 HYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLF 1657
HYD+G+R + SVL G K P + ES +++R L D+NL+K + +D PLF +I DLF
Sbjct: 2150 HYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLF 2209
Query: 1658 PGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKT 1717
P ++L K Y ++ +++ L P + K+IQ++E VRHG M +G GKT
Sbjct: 2210 PNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKT 2269
Query: 1718 SAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFR 1777
+ L A+ D ++ +NPKAIT Q++G D +++W DG+ + +R
Sbjct: 2270 TCIHTLMRAMTDCGKPHREMR-------MNPKAITAPQMFGRLDVATNDWTDGIFSTLWR 2322
Query: 1778 EQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADL 1837
+ + + WII DGPVDAIWIEN+N+VLDDNK L L +G+ I M +IFEP ++
Sbjct: 2323 KTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNI 2382
Query: 1838 EQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEF 1897
+ ASPATVSR GM++M L W P+ + ++ + ++L + F L + C++
Sbjct: 2383 DNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQ- 2441
Query: 1898 GRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLF 1957
L K V L ++ ++L + ++E+ E+ + L LF+F
Sbjct: 2442 -NLEYKMEV------LEAFVITQSINMLQGLIPLKEQGGEVSQA--------HLGRLFVF 2486
Query: 1958 SLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIK 2017
+L+W+ + D R++ +++ R+ G + P + +D+Y
Sbjct: 2487 ALLWSAGAALELDGRRRLELWLRSRPTGTLELPPPAGP-----------GDTAFDYYVAP 2535
Query: 2018 QASG-HWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPT 2076
+ HW T TQ + P + +++P ++ R F ++T +L +G
Sbjct: 2536 DGTWTHWNTRTQEYLYPSDTTP---EYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQ 2592
Query: 2077 GTGKSAITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKA 2136
GT K+ I F+ ++ +NFS+ T+ Q I S +D+R +GPP GKK
Sbjct: 2593 GTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKM 2652
Query: 2137 VVFVDDLNMPAKEVYGAQPPIELLRQWID-HGYWFDKKDTTRLDIVDMLLVTAMGPPGGG 2195
VF+DD+NMP +G Q E++RQ ++ +G++ +K IVD+ + AM PGGG
Sbjct: 2653 TVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGG 2712
Query: 2196 RNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHF--GKGFDVMFLRYGKMLVQATKT 2253
RNDI R R +I + + + KIF I H+ +GF LV T+
Sbjct: 2713 RNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRR 2772
Query: 2254 IYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYD 2313
+++ LPTP+K HYVFNLRD SRV QG+L +++ ++LW HE RV D
Sbjct: 2773 LWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIAD 2832
Query: 2314 RLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQ 2373
R D F + F + +K+L+ VD + E+D
Sbjct: 2833 RFTVSSDVTWFDKALVSLVEEEFGEE-KKLLVDCGIDTYFVDFLRDAPEAAGETSEEADA 2891
Query: 2374 ---KIYDEITDLKQLTVVMEHYLEEFN-NISKAPMSLVMFRFAIEHISRICRVLKQDKGH 2429
KIY+ I L + +L+ +N +I A M +V F A+ H+ +I RV++ +G+
Sbjct: 2892 ETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGN 2951
Query: 2430 LLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVF 2489
LLVG+GGSG+QS +L++F+ Y +QI +T++Y ++ EDLK + G K F
Sbjct: 2952 ALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITF 3011
Query: 2490 LFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMY 2549
+F DN+IKDESF+E +N +L++G+V N+F DE +I + + + + + T +++
Sbjct: 3012 IFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLH 3071
Query: 2550 NFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLE 2609
++F+ RV + L SP+G+ FRNR FP+LI+ CTIDWF WP DAL V+ FL
Sbjct: 3072 DYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLT 3131
Query: 2610 DVELDDNIRV--EVVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNS 2667
++D ++ + EVV FQ+ V + +DY+ + RR +VTP SYL I +K +
Sbjct: 3132 SYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGE 3191
Query: 2668 KRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETRE 2727
K EV + NR TGL+KL A+ VA + +EL A + +L + +++ ++ ++ + +
Sbjct: 3192 KHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQA 3251
Query: 2728 ADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKS 2787
A+ K VQ + A K E L A PALE A AAL T+ P+DI+ V++
Sbjct: 3252 AEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRT 3311
Query: 2788 MQNPPGPVKLVMESICIMKGMKPER-KPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTY 2846
+ PP + +M+ + ++ K K D S M W S K++ FL++L+ +
Sbjct: 3312 LGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPS--WQESLKLMTAGNFLQNLQQF 3369
Query: 2847 DKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRE 2906
KD I ++ + F P++ K V GLC W +AM + + K V P +
Sbjct: 3370 PKDTINEEVIEFLSPYF-EMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKA 3428
Query: 2907 RLREAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVR 2966
L E + MQ L + +AEL L + ++E+ T+K+ L E+ E C K+
Sbjct: 3429 NLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQT 3488
Query: 2967 AEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLA 3026
A LISGL GEK+RWTE +++ + L GDVLL++ ++Y G F ++R N W
Sbjct: 3489 ASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRK 3548
Query: 3027 ECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHG 3086
E K + IP + +LS L D I W + GLP D SI NGIIV+ + R+ L+IDP
Sbjct: 3549 EMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQT 3608
Query: 3087 QANKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKAT 3146
Q WIKN E N+L + + + LE++L LG P+LIE++GEELD +++ +L +
Sbjct: 3609 QGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNF 3668
Query: 3147 FKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLL 3206
K +++G+ ++ F+LYITT+L NP Y PE++ + +++F +T GL+DQLL
Sbjct: 3669 IKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLL 3728
Query: 3207 GIVAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSS 3266
G V EK ELE+++ L+ + NK+ +KE+ED +L L+ ++G+++EDE+ I VLS++
Sbjct: 3729 GRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNT 3788
Query: 3267 KVLSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFI 3326
K +EE+++K ++++ TE QI+ R Y+PVA + ++F I+++ + MYQ SL F+
Sbjct: 3789 KRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFL 3848
Query: 3327 NLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKK 3386
L+ SL S KS + RI II+H T +Y R L+E+ K LF+LLLT+ I Q+
Sbjct: 3849 GLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRN 3908
Query: 3387 EITEEVWYFLLTGGIALDNPYPNPAP-QWLSEKAWAEIVRASALPKLHGLMEHLEQNLGE 3445
+ E + L+ GG +LD P P +W+ + W +V S L + +++ + +N
Sbjct: 3909 RVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKM 3968
Query: 3446 WKLIYDSAWPHEEQLPGSW-KFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAP 3504
WK+ +D P EE LP ++ K +++++R PD+ + R++I + MG+ Y E
Sbjct: 3969 WKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGV 4028
Query: 3505 TFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAK 3564
DL+ ++ +S PLI +LS +DP ++ L + T+ +S+GQGQ A K
Sbjct: 4029 ILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKI---ETRYVSMGQGQEVHARK 4085
Query: 3565 MINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSI 3624
++ + +G W +LQNCHL +M +++ + +I E + FRLW+T+ ++FP+++
Sbjct: 4086 LLQQTMANGGWALLQNCHLGLDFM---DELMDIIIETELVHDAFRLWMTTEAHKQFPITL 4142
Query: 3625 LQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQER 3684
LQ IK N+PP+GLRA L R+Y +S + + W+ ML+ + F H+ VQER
Sbjct: 4143 LQMSIKFANDPPQGLRAGLKRTY--SGVSQDLL--DVSSGSQWKPMLYAVAFLHSTVQER 4198
Query: 3685 RNFGPLGWNIPYEFNESDLRISMWQIQMFLNDY---KEVPFDALTYLTGECNYGGRVTDD 3741
R FG LGWNIPYEFN++D ++ IQ L+D K V + + Y+ GE YGGRVTDD
Sbjct: 4199 RKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDD 4258
Query: 3742 KDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGL 3801
D+RLL + +++ + + +S G Y IP + +Y+ Y+++LP PEVFGL
Sbjct: 4259 YDKRLLNTFAKVWFSENMFGPDFSFYQG--YNIPKCSTVDNYLQYIQSLPAYDSPEVFGL 4316
Query: 3802 HENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQE-VVEELAQDILSKLPRDFDLEEV 3860
H NADIT ++ + + +L P+ + G G +E VV LA D+L KLP D+ EV
Sbjct: 4317 HPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEV 4376
Query: 3861 M-KLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSML 3919
+L + + MN LRQE+ R R+ +VR +L L AI G ++MS L + + M
Sbjct: 4377 KERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMF 4436
Query: 3920 VGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGV 3979
++PA W S+ S LG + +L+ R + F W+ G P FW++GF+ Q FLT +
Sbjct: 4437 DARIPAWWKKASWIS-STLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAM 4495
Query: 3980 SQNYAR-KYTIPIDHIGFEFEVTP-QETVMENNPEDGAYIKGLFLEGARWDRKTMQIGES 4037
Q R +D++ EVT + + P +G Y+ GL+LEGA WD++ M++ ES
Sbjct: 4496 RQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIES 4555
Query: 4038 LPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTD 4097
PK+L++ +P+I + E+ Y CP+YK R NY+ +++L T
Sbjct: 4556 KPKVLFELMPVIRIY-AENNTLRDPRFYSCPIYKKPVRT--------DLNYIAAVDLRTA 4606
Query: 4098 MPQKHWINRGVASLCQL 4114
+HW+ RGVA LC +
Sbjct: 4607 QTPEHWVLRGVALLCDV 4623
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 1868 bits (4838), Expect = 0.0
Identities = 1025/2281 (44%), Positives = 1405/2281 (61%), Gaps = 114/2281 (4%)
Query: 235 YYYLTNGIRKDMIAPEEGEVMVRISKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKS 294
Y Y+ + + P + E + + +LI +L E L+ L+ E +D+ S+ +
Sbjct: 96 YIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRY 155
Query: 295 IVDYILMDPMERKRLFIESIPRLFPQRVIRAPV--PWHSVYRSAKKWNEEHLHTVNPMML 352
+V +L+ P + +E P+ + PWHS Y A+ +LH ++P M
Sbjct: 156 LVQSVLVKPPVKS---LEDEGGPLPESPVGLDYSNPWHSSYVQARNQIFSNLHIIHPTMK 212
Query: 353 RLKELWFAEFRDLRFVRTAEILAGKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLF 412
L +L + F D + I A K P+ + + A + ++N W P LF
Sbjct: 213 MLLDLGYTTFADTVLLDFTGIRA-KGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLF 271
Query: 413 TSRKEHWIHFAPKSNYDSSRNIEEYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGND 472
T +KE P+ ++ +++ V++ MS QL++L+ +++E V LF
Sbjct: 272 T-KKEALEGVKPEK-------LDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF-------- 315
Query: 473 FKEPYQEMKFFIPQLIMIKLEVSEPIIVFNPSFDGCWELIRDSFLEIIKN-SNGIPKLKY 531
+P + + + I+L + + F P+F + D+ L +++ + + ++
Sbjct: 316 --DPKDQQRL---PIFKIELTFDDDKMEFYPTFQD----LEDNVLSLVERIAEALQNVQT 366
Query: 532 IPLKFSFTAAAADRQCVKAAEPGEPSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQ 591
IP S T+ + E H A+ LK
Sbjct: 367 IPSWLSGTSTPVNLDT-------ELPEHVLHWAVDTLKA--------------------- 398
Query: 592 TFKVFQKNQVGPCKYLNVY-KKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRN 650
+N G K+ Y +KY LLD TA +NI F E+H D++ I +
Sbjct: 399 ---AVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLAS 455
Query: 651 EIASMNITVPLAMFCLDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIAD 710
EI + + M LD L L +A+ + L+ R N IC+++ I +
Sbjct: 456 EIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFANILLNDIASKYRKENECICSEFEAIKE 515
Query: 711 KVSEVPANTKELVSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDY-----ADL----- 760
+VP T+E++ LI +++K+ V + +L +++++ ++ + +D DL
Sbjct: 516 HALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMSYFLDVFLFPQEDLALNAT 575
Query: 761 ----PYQIEDIFDNSRNLLLHKRDQAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTE 816
P +I IFD + L+ + + + E +L+ + + L +E R +E F E E
Sbjct: 576 VLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFT--EFAELE 633
Query: 817 EMKHNVEKLNELSKNLNRAFAEFELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTA 876
M+ V + +L K + + + INKEEEL + E + YP L + N PY++ ++
Sbjct: 634 RMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFV 693
Query: 877 YEFSIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLS-----DVPAPRRLAENVK 931
++ + WM+G LN E + ++ R +K +K ++ R+ A
Sbjct: 694 LKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRS 753
Query: 932 IKIDKFKQYIPILSISCNPGMKDRHWQQISEIVGYEIKPTETTCLSNMLEFGFGKFVEKL 991
++ +K ++ + M+ RHW+QISEIVGY++ P T L +L+ ++E+
Sbjct: 754 LEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQF 813
Query: 992 EPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVKYRDTDTNILCAIDDIQMLLDDHVIKTQ 1051
E I A ASKE+SLEK ++ M W ++ F YRDT IL ++D+IQ +LDD +IKTQ
Sbjct: 814 EVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQ 873
Query: 1052 TMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGR 1111
TM GSPFIKP E E + WE++LIRIQ+ +D WLK QA WLYLEPIF SEDI+ QMPEEGR
Sbjct: 874 TMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGR 933
Query: 1112 KFGIVDSYWKSLMSQAVKDNRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFF 1171
+F VD +W+ +M KD ++L A + EKLQ N LLE I KGLN YLEKKRLFF
Sbjct: 934 QFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFF 993
Query: 1172 PRFFFLSNDELLEILSETKDPLRVQPHLKKCFEGIAKLEFTDNLEIVGMISSEKETVPFI 1231
PRFFFLSNDE+LEILSETKDPLRVQPHLKKCFEGIAKLEF NL+I M SSE E V I
Sbjct: 994 PRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNLDIKAMYSSEGERVELI 1053
Query: 1232 QKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSS 1291
I + A+G VEKWL QVE +ML S+ +VI AY + R WV +WPGQVV+C+S
Sbjct: 1054 ALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCISQ 1113
Query: 1292 IFWTQEVSQALAENT--LLDFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARD 1349
+FWT E + ++ T L + K+ +Q+ +IV+LVRGKLS R TLGAL IDVHARD
Sbjct: 1114 MFWTSETQEVISGGTEGLKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARD 1173
Query: 1350 VVAKLSEDRVSDLNDFQWISQLRYYWVAKDVQVQIITTEALYGYEYLGNSPRLVITPLTD 1409
VV + + VS DF W++QLRYYW ++ +V+II Y YEYLGNSPRLVITPLTD
Sbjct: 1174 VVMDMIKMGVSHDTDFLWLAQLRYYWENENARVRIINCNVKYAYEYLGNSPRLVITPLTD 1233
Query: 1410 RCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFK 1469
RCYRTL+GA LNLGGAPEGPAGTGKTETTKDLAKALA QCVVFNCSDGLDY AMGKFFK
Sbjct: 1234 RCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFK 1293
Query: 1470 GLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFI 1529
GLA +GAWACFDEFNRIE+EVLSVVAQQIL IQ+AI +KL F+FEGTEL LNP C V I
Sbjct: 1294 GLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAI 1353
Query: 1530 TMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLC 1589
TMNPGYAGR+ELPDNLK LFRTVAMMVP+YALI EISLYS GFL++R L+ KIV TYRLC
Sbjct: 1354 TMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLC 1413
Query: 1590 SEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLF 1649
SEQLSSQ HYDYGMRAVK+VL AAGNLKLKYP ENE +LLLR++ DVN KFL+ D+PLF
Sbjct: 1414 SEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLF 1473
Query: 1650 QGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIV 1709
GI SDLFPG+ LP+ DY FL+ ++ LQPV +F+ KIIQ YEMM+VRHG+M+V
Sbjct: 1474 NGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLV 1533
Query: 1710 GDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMD 1769
G+P KT VLA L ++ EE V Y+ +NPK+ITMGQL+G FD VSHEW D
Sbjct: 1534 GEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTD 1593
Query: 1770 GVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMS 1829
G++AN FRE A S + DRKW++FDGP+D +WIE+MNTVLDDNKKLCLMSGEIIQM+ +MS
Sbjct: 1594 GIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMS 1653
Query: 1830 LIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTK-EHKELVNDMFM 1888
LIFE DL QASPATVSRCGMIY+EP QLGW+PL S++++L L + E++ L+ +F
Sbjct: 1654 LIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQALLRGLFA 1713
Query: 1889 WLVQPCL-------EFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEG 1941
WL+ P L + L+ V + I + F + + + + L
Sbjct: 1714 WLIPPSLNQRVELFQLNYLYTTIVSKILKILITFRISNYF------------KYVPLKTQ 1761
Query: 1942 LSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKN 2001
+ + FL Q F+FSL+W++ G+ + D R+ FD F R +I+G DD +P P SV +
Sbjct: 1762 CTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWEC 1821
Query: 2002 NIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLK 2061
F E+G +YD+ + + G W W + I K K+ ++I+PTM+T R +F +
Sbjct: 1822 P-FDEKGLVYDYMYELKNKGRWVHWNELI-KNTNLGDKQIKIQDIIVPTMDTIRYTFLMD 1879
Query: 2062 TYLDHEIPMLFVGPTGTGKSAITNNFLL-HLPKNTYLPNCINFSARTSANQTQDIIMSKL 2120
+ + P+LFVGPTGTGKS + L+ HL K+ Y P IN SARTSANQ Q+IIM++L
Sbjct: 1880 LSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARL 1939
Query: 2121 DRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDI 2180
D+RRKG+FGPP+GKK ++F+DD+NMPA E YGAQPPIELLRQ+ D G+W+D KDT+++ +
Sbjct: 1940 DKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSKITL 1999
Query: 2181 VDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHF-GKGFDVM 2239
VD+ L+ AMGPPGGGRN +T R RH NI SIN+F D+ + +IFSSIV ++ F
Sbjct: 2000 VDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPE 2059
Query: 2240 FLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKC 2299
+ G +V T IY+ +VEN LPTP+KSHY FNLRDFSRVI+G LL + +
Sbjct: 2060 YFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVANKHTM 2119
Query: 2300 IRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHL-SPTGKIVDDNI 2358
IRL++HEV RVFYDRLI+ +DR+ F + K + FK++ + HL + ++++
Sbjct: 2120 IRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVTEEDL 2179
Query: 2359 RSLFFGDYFKP--ESDQKIYDEITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHI 2416
R+L FGDY P E D ++Y EI ++ + V++ L+E+N K M+LV+FR+ +EH+
Sbjct: 2180 RNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVIFRYVLEHL 2239
Query: 2417 SRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKI 2476
SRICRVLKQ G+ LLVG+GGSGRQS +L+T M ++Q EI+K+Y N+WRED+K
Sbjct: 2240 SRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKSF 2299
Query: 2477 I 2477
I
Sbjct: 2300 I 2300
Score = 972 bits (2512), Expect = 0.0
Identities = 463/784 (59%), Positives = 593/784 (75%), Gaps = 8/784 (1%)
Query: 3338 KSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLL 3397
KS+ L R++Y+ DHFT ++Y N+CRSLFEKDKLLFS LL ++ +KEI + FLL
Sbjct: 2312 KSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLL 2371
Query: 3398 TGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHE 3457
TGG++L + NP P WL +K+W EI RAS P GL +H +++ EW+ IYDS PH
Sbjct: 2372 TGGVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHN 2431
Query: 3458 EQLPGSW-KFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSS 3516
+ P K L+K++ILRCLRPDK+ PA+ ++ + +GK ++E P FDL SY DS+
Sbjct: 2432 AKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSN 2491
Query: 3517 CCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWV 3576
C PLIFVLSP ADPMA LLKFA+D M G + Q ISLGQGQGPIAAKMI AI++GTWV
Sbjct: 2492 CTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWV 2551
Query: 3577 VLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPP 3636
LQNCHLA SWMP LEKICE+ E+ N+ FRLWLTSYPS KFPV+ILQNG+KMTNEPP
Sbjct: 2552 CLQNCHLAVSWMPMLEKICED-FTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPP 2610
Query: 3637 KGLRANLLRSYLNDPISDPVFFQSC-AKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIP 3695
GLR NLL+SYL DP+SDP FF+ C K + W+K+LFG+CFFHA+VQER+ FGPLGWNIP
Sbjct: 2611 TGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIP 2670
Query: 3696 YEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFY 3755
Y FNESDLRIS+ Q+Q+F+N+Y +PF+A++YLTGECNYGGRVTDD DRRLLL++L+ FY
Sbjct: 2671 YGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFY 2730
Query: 3756 CKEIEED-YYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQET 3814
I E+ +Y +P Y+ PP G+Y+ YI++++ LP T HPE+FGLHEN DI+KD Q+T
Sbjct: 2731 NLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQT 2790
Query: 3815 NQLFEGVLLTL--PRQSGGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESM 3872
LFE +LLT +Q+G SG + Q ++ E+ +DIL+KLP DFD+E ++ YPV YEESM
Sbjct: 2791 KTLFESLLLTQGGSKQTGASGSTDQ-ILLEITKDILNKLPSDFDIEMALRKYPVRYEESM 2849
Query: 3873 NTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSY 3932
NTVL QE+ RFN L +R +L +L +AIKG V+M S LE + S+LVGKVP +WA +SY
Sbjct: 2850 NTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSY 2909
Query: 3933 PSLKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPID 3992
PSLKPLG Y+ D LARL F Q+W + G P VFW+SGF+FTQ+FLTG QNYARKYT PID
Sbjct: 2910 PSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPID 2969
Query: 3993 HIGFEFEVTPQETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLK 4052
+G+EFEV P +T + +PEDG YI GL+L+GARWDR++ + E PK+L+D +PIIW+K
Sbjct: 2970 LLGYEFEVIPSDT-SDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIK 3028
Query: 4053 PGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLC 4112
P + + + D YVCP+YKTS R+GTLSTTGHSTN+V+++ L TD P +HWI RGVA LC
Sbjct: 3029 PTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLC 3088
Query: 4113 QLDN 4116
QLD+
Sbjct: 3089 QLDD 3092
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 1821 bits (4718), Expect = 0.0
Identities = 1133/3335 (33%), Positives = 1776/3335 (53%), Gaps = 182/3335 (5%)
Query: 844 KEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEEI 903
KE LL+K Y + + + YE LW ++ E+I E+
Sbjct: 1273 KELNLLQKLYGLYDTVMSSISGY--YEILWGD------------------VDIEKINAEL 1312
Query: 904 GNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISEI 963
KL K L D A ++K +ID F + P+L + N MK RHW +ISE+
Sbjct: 1313 LEFQNRCRKLPKGLKDWQA----FLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISEL 1368
Query: 964 VG--YEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFS 1021
G ++++ +++ CL N++E K + +E I +A KE +E L ++ +W N S
Sbjct: 1369 TGTPFDVE-SDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLS 1427
Query: 1022 FVKYRDTDTNILCAID--DIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDN 1079
F ++ +L + +I L++D ++ ++ + + P + + W KL D
Sbjct: 1428 FAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDI 1487
Query: 1080 LDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKD-NRILVAAD 1138
++ WL Q W+YLE +F DI Q+P+E ++F +D W +M +A ++ N I
Sbjct: 1488 IEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVG 1547
Query: 1139 QPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPH 1198
M + L + LE QK L YLEKKRL FPRFFF+S+ LLEIL + D +QPH
Sbjct: 1548 DETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPH 1607
Query: 1199 LKKCFEGIAKLEF--TDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLA 1256
L + I ++ F D I+ +IS E E + + AKG VE WL + +M ++
Sbjct: 1608 LPAVSDNINEVTFHAKDYDRIMAVISREGEKIVLDNSVM---AKGPVEIWLLDLLKMQMS 1664
Query: 1257 SMREVIGLGIEAYVKVPRNHWVL-----QWPGQVVICVSSIFWTQEVSQALA-------- 1303
S+ +I A+ ++ + + L +P QV + + WT + +AL
Sbjct: 1665 SLHNIIR---SAFYQISDSGFQLLPFLSHFPAQVGLLGIQMLWTHDSEEALRNAKDDRKI 1721
Query: 1304 -ENTLLDFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDL 1362
+ T FL N I+Q LS R+ L I VH RD+ L + +
Sbjct: 1722 MQVTNQKFLDILNTLISQTTH----DLSKFDRVKFETLITIHVHQRDIFDDLVKMHIKSP 1777
Query: 1363 NDFQWISQLRYYWVAKDVQ--VQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALK 1420
DF+W+ Q R+Y+ Q V I + +Y E+LG + RLVITPLTDRCY TL AL
Sbjct: 1778 TDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALG 1837
Query: 1421 LNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACF 1480
+N+GGAP GPAGTGKTETTKD+ + L K VVFNCSD +D++ +G+ FKGLAQ+G+W CF
Sbjct: 1838 MNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCF 1897
Query: 1481 DEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIF-EGTELSLNPTCAVFITMNPGYAGRA 1539
DEFNRIE+ VLSV AQQI + A + K FIF +G + LNP +F+TMNPGYAGR
Sbjct: 1898 DEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQ 1957
Query: 1540 ELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHY 1599
ELP+NLK FRTVAMMVPD +I + L S GFL++ LAQK Y+LC EQL+ Q HY
Sbjct: 1958 ELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHY 2017
Query: 1600 DYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPG 1659
D+G+R + SVL G+ K PE++E +++R L D+NL+K + +D PLF +I+DLFPG
Sbjct: 2018 DFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPG 2077
Query: 1660 VVLPKPDYEVFLKVLNDNIK-KMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTS 1718
+ L Y + ++ + + PW + K++Q+YE LVRHG M +G GKT+
Sbjct: 2078 LQLDSNTYAELQNAVAHQVQIEGLINHPPWNL-KLVQLYETSLVRHGLMTLGPSGSGKTT 2136
Query: 1719 AYKVLAAA---LGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANA 1775
+L A G H +M NPKAIT Q++G D +++W DG+ +
Sbjct: 2137 VITILMKAQTECGRPHREMRM----------NPKAITAPQMFGRLDTATNDWTDGIFSTL 2186
Query: 1776 FREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPA 1835
+R+ + + ++I DGPVDAIWIEN+N+VLDDNK L L +G+ I M L+FE
Sbjct: 2187 WRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVH 2246
Query: 1836 DLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSS----LTKEHKELVNDMFMWL- 1890
++E ASPATVSR GM+Y+ L W+P+ +++ + ++++ D + ++
Sbjct: 2247 NIENASPATVSRMGMVYISSSALSWRPILQAWLKKRTAQEAAVFLTLYEKVFEDTYTYMK 2306
Query: 1891 --VQPCLEFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIF 1948
+ P ++ L C ++VQ+ +LL+ + +EE G+S +
Sbjct: 2307 LNLNPKMQL--LECNYIVQSL-------------NLLEGLIPSKEEG-----GVSCVE-- 2344
Query: 1949 LWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERG 2008
L LF+F L+W++ + +SR+K + F R +D P+ K +
Sbjct: 2345 -HLHKLFVFGLMWSLGALLELESREKLEAFLRQHESKLD----LPEIPKGSNQ------- 2392
Query: 2009 SIYDFYFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEI 2068
++Y+FY G WE W + + + + S +++P ++ R +F + T
Sbjct: 2393 TMYEFYVTDY--GDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQHK 2450
Query: 2069 PMLFVGPTGTGKSAITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLF 2128
+L G GT K+ + +L L +NFS+ T Q I S +D+R +
Sbjct: 2451 AVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGSTY 2510
Query: 2129 GPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWID-HGYWFDKKDTTRLDIVDMLLVT 2187
GPP G+K VF+DD+NMP +G Q E++RQ ++ G + K IVD+ L+
Sbjct: 2511 GPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIA 2570
Query: 2188 AMGPPGGGRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHFG--KGFDVMFLRYGK 2245
AM PGGGRNDI R R + + + + KIF I +F + F
Sbjct: 2571 AMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKPQICEMIV 2630
Query: 2246 MLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIH 2305
LV + +++ LPTPSK HY+FNLRD SR+ QG+L + + L+ H
Sbjct: 2631 NLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKH 2690
Query: 2306 EVYRVFYDRLIDKEDRQVF-FNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFG 2364
E RV DR I ED Q F ++ + N +L P VD F
Sbjct: 2691 ECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCIL----PEPYFVD------FLR 2740
Query: 2365 DYFKPESDQ---------KIYDEITDLKQLTVVMEHYLEEFNNISKAP-MSLVMFRFAIE 2414
+ +P D+ KIY+ + L ++ Y +FN I + + LV F+ A+
Sbjct: 2741 EMPEPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMT 2800
Query: 2415 HISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLK 2474
H+ +I R+++ G+ LLVG+GGSG+QS ++L++F+ Y+++QI +T++Y + +DLK
Sbjct: 2801 HLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLK 2860
Query: 2475 KIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAA 2534
+ G K F+F D++IKDE+F+E +N LL++G++ N+F DE +I + + +
Sbjct: 2861 ALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVM 2920
Query: 2535 RTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQS 2594
+ + + T ++Y +FI R + L SP+G+ FR R FP LI+ CT+DWF
Sbjct: 2921 KRELPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSR 2980
Query: 2595 WPTDALELVANKFLEDVEL--DDNIRVEVVSMCKYFQESVKKLSLDYYNKLRRHNYVTPT 2652
WP +AL VA+ FL D + I+ +VV F + V + Y+ + RR +VTP
Sbjct: 2981 WPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPK 3040
Query: 2653 SYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSE 2712
SYL I +K + K + + R GL KL A+ VA + ++L + +L + S
Sbjct: 3041 SYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASI 3100
Query: 2713 ETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAALA 2772
+ +++ ++ + + K VQ + +A K + E L A PALE A A
Sbjct: 3101 KADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEA 3160
Query: 2773 ALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKP-DPSGSGKMIEDYWGVSK 2831
AL+T+ P DI+ V+ + PP + +M+ + ++ K + DP S + WG S
Sbjct: 3161 ALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKS--CCKPSWGESL 3218
Query: 2832 KILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGLCKWVRAM 2891
K++ FL SL+ + KD I T++ ++ F N ++ K V GL W AM
Sbjct: 3219 KLMSATGFLWSLQQFPKDTINEETVELLQPYF-NMDDYTFESAKKVCGNVAGLLSWTLAM 3277
Query: 2892 EVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKK 2951
++ + + V P + L + EG+LA +L + +A L L + F+ +K
Sbjct: 3278 AIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKM 3337
Query: 2952 DLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGA 3011
DL + + C +K+ A LI GL GEK RWT+ +++ + L GD+LL +G ++YLG
Sbjct: 3338 DLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGP 3397
Query: 3012 FTVDYR-VQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGI 3070
F +R ++QW E + + IP + +L L DP I W + GLP D SI NGI
Sbjct: 3398 FNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGI 3457
Query: 3071 IVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENI 3130
IV+ + R+ L+IDP Q WIK+ EK N L V + + LE++L LG P+LIE+I
Sbjct: 3458 IVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDI 3517
Query: 3131 GEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVC 3190
EELD +++ +L K K +++G+ + FKLYITT+L NP + PE+ K
Sbjct: 3518 HEELDPALDNVLEKNFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTS 3577
Query: 3191 LLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSK 3250
+++F +T GL++QLL V EK ELE ++ +L+ + NK+ +KE+ED +L LS +K
Sbjct: 3578 VIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATK 3637
Query: 3251 GNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISD 3310
G++++DE+ I VL ++K + E+SEK VA+ TE +I+ + ++P A + ++F I++
Sbjct: 3638 GSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITE 3697
Query: 3311 LANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDK 3370
++ + MYQ SL F+ L+ S+ S KS RI II++ T ++ R L+E K
Sbjct: 3698 MSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHK 3757
Query: 3371 LLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPYPNPAP-QWLSEKAWAEIVRASAL 3429
LF LL+T+ I Q+ + + L+ GG ALD P P +W+ + W +V S L
Sbjct: 3758 FLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKL 3817
Query: 3430 PKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFS-QGLEKMVILRCLRPDKMVPAV 3488
P+ +M + +N WK +D P EE +P + S K++++R PD+ V
Sbjct: 3818 PQFAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQA 3877
Query: 3489 REFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTR 3548
R++IA+ + + Y E +L+ ++ +S PLI LS +DP + A L +
Sbjct: 3878 RKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKL---E 3934
Query: 3549 TQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARF 3608
+TIS+GQGQ A K+I +++ G WV+LQNCHL +M E++ E +I E+++ F
Sbjct: 3935 CRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM---EELLETLITTEASDDSF 3991
Query: 3609 RLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSY--LNDPISDPVFFQSCAKAVM 3666
R+W+T+ P ++FP+++LQ +K TNEPP+G+RA L R++ +N + D + M
Sbjct: 3992 RVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD------ISNLPM 4045
Query: 3667 WQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLND---YKEVPFD 3723
W+ ML+ + F H+ VQERR FGPLGWNIPYEFN +D S+ IQ L++ K V ++
Sbjct: 4046 WKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWN 4105
Query: 3724 ALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSY 3783
+ Y+ GE YGGRVTDD D+RLL +++ +++ E + G Y IP + Y
Sbjct: 4106 TVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEPSFCFYTG--YKIPLCKTLDQY 4163
Query: 3784 IDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQSGGS-GKSPQEVVEE 3842
+Y+++LP +PEVFGLH NADIT + + + E + P++SGG G++ + +V
Sbjct: 4164 FEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYR 4223
Query: 3843 LAQDILSKLPRDFDLEEV-MKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAI 3901
L++D+LSKLP D+ EV +L + + SMN LRQE+ R R+ ++R SL +L AI
Sbjct: 4224 LSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAI 4283
Query: 3902 KGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPP 3961
+G ++MS L + ++M ++P +W S+ S LG + +LL R F WI +G P
Sbjct: 4284 EGTIIMSENLRDALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRP 4342
Query: 3962 VVFWISGFYFTQSFLTGVSQNYARKYT-IPIDHIGFEFEVTPQ-ETVMENNPEDGAYIKG 4019
VFW++GF+ Q FLT + Q R + +D + EV Q + + + P +G YI G
Sbjct: 4343 NVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYG 4402
Query: 4020 LFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTL 4079
L+++GA WDR+ ++ ES PK+L+ LP++ + S +YVCP+YK R
Sbjct: 4403 LYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRT--- 4459
Query: 4080 STTGHSTNYVLSIELPTDMPQKHWINRGVASLCQL 4114
++ + L T + HWI RGVA LC +
Sbjct: 4460 -----DLTFITVVYLRTVLSPDHWILRGVALLCDI 4489
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 1256 bits (3249), Expect = 0.0
Identities = 922/3412 (27%), Positives = 1633/3412 (47%), Gaps = 345/3412 (10%)
Query: 913 LIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISC---NPGMKDRHWQQISEIVGYEIK 969
L+ L PA R + + K Y+ I + + +KDRHW+Q+ + +
Sbjct: 1366 LLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWV 1425
Query: 970 PTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVKYRDTD 1029
+E T L + + K ++ + A E +LE+ L +++ W V Y++
Sbjct: 1426 VSELT-LGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNK- 1483
Query: 1030 TNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLKCQAT 1089
++ DD+ + +H+ M SP+ K E + WE+KL RI D W+ Q
Sbjct: 1484 CRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRR 1543
Query: 1090 WLYLEPIFS-SEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPRMAEKLQE 1148
W+YLE IF+ S DI +P E ++F + + + +LM + K ++ + + L+
Sbjct: 1544 WVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLER 1603
Query: 1149 ANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKKCFEGIAK 1208
LL IQK L +YLE++R FPRF+F+ +++LLEI+ +K+ ++Q H KK F G++
Sbjct: 1604 LADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSS 1663
Query: 1209 LEFT-DNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGI- 1266
+ DN ++G+ S E E V F + + +WL VE+ M ++ +++ +
Sbjct: 1664 IILNEDNSVVLGISSREGEEVMFKTPV-SITEHPKINEWLTLVEKEMRVTLAKLLAESVT 1722
Query: 1267 --EAYVKV----PRNH--WVLQWPGQVVICVSSIFWTQEVSQALAE----------NTLL 1308
E + K P + W+ ++ Q+V+ + I W++ V AL+ +++L
Sbjct: 1723 EVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVL 1782
Query: 1309 DFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWI 1368
++ + + +A V + + L R L L VH RDV L + ++ + F+W+
Sbjct: 1783 SNVEVTLNVLADSVLMEQPPLR---RRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWL 1839
Query: 1369 SQLRYYW------VAKDVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLN 1422
SQ+R+Y+ V + + +Q+ + YG+EYLG +LV TPLTDRCY T+ AL+
Sbjct: 1840 SQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEAR 1899
Query: 1423 LGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDE 1482
LGG+P GPAGTGKTE+ K L L + +VFNC + D++AMG+ F GL Q GAW CFDE
Sbjct: 1900 LGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDE 1959
Query: 1483 FNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGT-----------ELSLNPTCAVFITM 1531
FNR+E +LS V+QQ+ IQ+A+ R+ ++ T ++ ++P A+FITM
Sbjct: 1960 FNRLEERMLSAVSQQVQCIQEAL-REHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITM 2018
Query: 1532 NPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSE 1591
NPGYAGR+ LPDNLK LFR++AM PD LI ++ LYS GF + LA KIV ++LC E
Sbjct: 2019 NPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDE 2078
Query: 1592 QLSSQHHYDYGMRAVKSVLTAAGNLK------LKYPEEN---------------ESVLLL 1630
QLSSQ HYD+G+RA+KSVL +AGN+K +K +E E +L+
Sbjct: 2079 QLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILI 2138
Query: 1631 RALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKL------Q 1684
+++ + + K +A+D+PL ++SD+FPGV + + + L ++M L +
Sbjct: 2139 QSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEE 2198
Query: 1685 PVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYK 1744
++ K++Q+Y++ + HG M+VG GK+ A++VL AL L +
Sbjct: 2199 VGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAH------ 2252
Query: 1745 IINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDD---RKWIIFDGPVDAIWI 1801
II+PKAI+ LYG D + EW DG+ + R+ S+ + R+WI+FDG VD W+
Sbjct: 2253 IIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWV 2312
Query: 1802 ENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWK 1861
EN+N+VLDDNK L L +GE + + + ++FE DL+ A+ ATVSRCGM++ L
Sbjct: 2313 ENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTD 2372
Query: 1862 PLKDSYMDTLPS---------------SLTKEHKELVNDMFM------WLVQPCLEFGRL 1900
+ ++++ L S E +E + M ++QP L
Sbjct: 2373 MIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGL 2432
Query: 1901 HCKFVVQTSPIHLAFSMMRL------YSSLLDEIRAVEEEEMELGE-GLSSQQIFLWLQG 1953
K + + + RL +S L R V + + + +Q+ ++Q
Sbjct: 2433 VTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQR 2492
Query: 1954 LFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDF 2013
+++++W+++G R + + R + P P T NI I D+
Sbjct: 2493 YLVYAILWSLSGDSRLKMRAELGEYIRRIT-----TVPLP-----TAPNI-----PIIDY 2537
Query: 2014 YFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFV 2073
SG W W + + E + A ++++PT++T R L T+L P++
Sbjct: 2538 EV--SISGEWSPWQAKVPQIEVETHKVA-APDVVVPTLDTVRHEALLYTWLAEHKPLVLC 2594
Query: 2074 GPTGTGKSAITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLD------RRRKGL 2127
GP G+GK+ + L LP + +NFS+ T T ++++ D R G+
Sbjct: 2595 GPPGSGKTMTLFSALRALPDMEVVG--LNFSSAT----TPELLLKTFDHYCEYRRTPNGV 2648
Query: 2128 FGPPI--GKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLL 2185
P+ GK V+F D++N+P + YG Q I +RQ ++HG ++ D T + + +
Sbjct: 2649 VLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQF 2708
Query: 2186 VTAMGPPGG-GRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHFGKGFDVMFLR-- 2242
V A PP GR ++ RF RH+ ++ ++ LT+I+ + F+ LR
Sbjct: 2709 VGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGT---------FNRAMLRLI 2759
Query: 2243 -----YGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVL--LCPHTHLQD 2295
Y + L A Y + E F ++ HY+++ R+ +R ++G+ L P L
Sbjct: 2760 PSLRTYAEPLTAAMVEFYTMSQERFTQD-TQPHYIYSPREMTRWVRGIFEALRPLETLP- 2817
Query: 2296 VEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVD 2355
VE IR+W HE R+F DRL++ E+R+ + I+ V + P
Sbjct: 2818 VEGLIRIWAHEALRLFQDRLVEDEERR------------WTDENIDTVALKHFPNIDREK 2865
Query: 2356 DNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEH 2415
R + + ++ + +E+ D + + + Y EE + + LV+F ++H
Sbjct: 2866 AMSRPILYSNWLSKDYIPVDQEELRDYVKARLKV-FYEEELD------VPLVLFNEVLDH 2918
Query: 2416 ISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKK 2475
+ RI R+ +Q +GHLLL+G+ G+G+ + ++ +MN +YQI++ + Y G D+ EDL+
Sbjct: 2919 VLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRT 2978
Query: 2476 IILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAAR 2535
++ + G + F+ ++ + D F+E +N LL G+VP +F DE A ++ + + A+
Sbjct: 2979 VLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQ 3038
Query: 2536 TQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSW 2595
+G ++ + +Y +F +VI + M+P + ++R P+L N C ++WF W
Sbjct: 3039 KEGLMLD-SHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDW 3097
Query: 2596 PTDALELVANKFLEDVELDD--------------------NIRVEVVSMCKYFQESVKKL 2635
T+AL V +F ++L+ + R +V+ C + +++ +
Sbjct: 3098 STEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQA 3157
Query: 2636 SLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAV 2695
+ + R +TP YL+ I + L + KR E+ + GL+K+ QV
Sbjct: 3158 NARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEE 3217
Query: 2696 MQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNE 2755
++R+L +L + + + K+ + +EA+ KK++ Q +++ + + +
Sbjct: 3218 LRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMS 3277
Query: 2756 CEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPD 2815
+ DL + PA+ A A+ ++ + V+SM NPP VKL +ESIC++ G E D
Sbjct: 3278 VKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLG---ESTTD 3334
Query: 2816 PSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIK 2875
W + I+ F+ ++ + + I +++++ ++++P + ++
Sbjct: 3335 -----------WKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVN 3383
Query: 2876 NVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDR 2935
S AC + KW A Y + K V P R L++ E QK N+ ++ +
Sbjct: 3384 RASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEAS 3443
Query: 2936 LQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNL 2995
+ +++ + ++ + ++ ++ K+ R+ L+ L E++RW + + + + +
Sbjct: 3444 IARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTI 3503
Query: 2996 TGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQ 3055
GD LLS+ +AY G F R W + I +D + + L + + WQ
Sbjct: 3504 AGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQ 3563
Query: 3056 IAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRML 3115
+ LP D +N I++ R+ L+IDP GQA ++I N K K+ F D + + L
Sbjct: 3564 ASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNL 3623
Query: 3116 ENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTR 3175
E+AL+ G P+L++++ E D + P+L + + G + LG+ I+ S F ++++TR
Sbjct: 3624 ESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTR 3682
Query: 3176 LRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHL 3235
+ P++ +V +NF +T LQ Q L V E+P+++EK++ L+ + + L
Sbjct: 3683 DPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRL 3742
Query: 3236 KEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYK 3295
+++E +L+ L+ KG IL+D+T I L + K + E++ K + + +++ Y
Sbjct: 3743 RQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYL 3802
Query: 3296 PVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHF-T 3354
P++ ++I+F + L I +YQYSL +F+++Y H+ E NL K + DH
Sbjct: 3803 PLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIY-----HNVLYENPNL--KGVTDHTQR 3855
Query: 3355 LSI---------YNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITE-----EVWYFLLTGG 3400
LSI +N V R + +D + F++LL +K K + E E +FL
Sbjct: 3856 LSIITKDLFQVAFNRVARGMLHQDHITFAMLL--ARIKLKGTVGEPTYDAEFQHFLRGNE 3913
Query: 3401 IALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHL--EQNLGEWKLIYDSAWPHEE 3458
I L + P Q L+ + +VR S LP L+ + ++ G W DS+ P E+
Sbjct: 3914 IVL-SAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIW---LDSSSP-EQ 3968
Query: 3459 QLPGSWK-------FSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGS 3511
+P W Q + ++++++ RPD+++ F++ ++G+ ++ L +
Sbjct: 3969 TVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLT 4028
Query: 3512 YNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQG-PIAAKMINNAI 3570
+ + P VL S D T+ +I++G +G A K IN A+
Sbjct: 4029 HIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAV 4088
Query: 3571 KDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIK 3630
K G WV+L+N HLA W+ LEK + +A FRL+LT + K PV++L+ G
Sbjct: 4089 KSGRWVMLKNVHLAPGWLMQLEKKLHSL----QPHACFRLFLTMEINPKVPVNLLRAGRI 4144
Query: 3631 MTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPL 3690
EPP G++AN+LR++ + P+S + C ++ F L +FHA++QER + PL
Sbjct: 4145 FVFEPPPGVKANMLRTFSSIPVS-----RICKSPNERARLYFLLAWFHAIIQERLRYAPL 4199
Query: 3691 GWNIPYEFNESDLRISMWQIQMFLNDY---------KEVPFDALTYLTGECNYGGRVTDD 3741
GW+ YEF ESDLR + + +L+D ++P+ AL L + YGGRV ++
Sbjct: 4200 GWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNE 4259
Query: 3742 KDRRLLLSLLSMFYCKEIEEDYYSLA---PGDTYYIPPHG-SYQSYIDYLRNLPITAHPE 3797
D+RLL + L + + + LA G P G + ++ ++ LP T P
Sbjct: 4260 FDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPS 4319
Query: 3798 VFGLHENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVVE---ELAQDILSKLPRD 3854
GL NA E VLLT S +++E +LA K R
Sbjct: 4320 WLGLPNNA-------------ERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRT 4366
Query: 3855 FDLEE---------------VMKLYPVVYEESMNTV--LRQELIRF--------NRLTKV 3889
+ + L P TV ++ L RF +L +
Sbjct: 4367 DSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQD 4426
Query: 3890 VRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARL 3949
VR+ L ++ + +G+ ++ L + N ++ G +P W+ + P+ + +V+D R+
Sbjct: 4427 VRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERI 4486
Query: 3950 TFFQE--------WIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVT 4001
Q + + + G + ++++T Q A+ + ++ + E VT
Sbjct: 4487 KQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVT 4546
Query: 4002 PQETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPL-PIIWLKPGESAMFL 4060
+ + G + GL L+GA + + + ++ L PL + W+K +
Sbjct: 4547 TSQGATLDACSFG--VTGLKLQGATCNNNKLSLSNAISTAL--PLTQLRWVKQTNTEK-- 4600
Query: 4061 HQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLC 4112
+ PVY L+ T + + E+ T + + RGVA LC
Sbjct: 4601 KASVVTLPVY--------LNFTRADLIFTVDFEIATKEDPRSFYERGVAVLC 4644
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 1187 bits (3072), Expect = 0.0
Identities = 943/3447 (27%), Positives = 1595/3447 (46%), Gaps = 314/3447 (9%)
Query: 796 RLEGYHRELESFRKR--------EVMTTEEMKHN-VEKLNELSKNLNRAFAEFELINKEE 846
RL+ Y++ELE F+ R +V+ T + HN ++K +L K F + E+ K+
Sbjct: 1043 RLQIYYQELEKFKARWDQLKPGDDVIETGQ--HNTLDKSAKLIKEKKIEFDDLEVTRKKL 1100
Query: 847 ----ELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQ-IAE 901
E+ + L ++ K+ Q+W+ EF +E N + + E
Sbjct: 1101 VDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFE 1160
Query: 902 EIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQIS 961
E W + ++ S + ++ ++DK+K IPIL + HW +
Sbjct: 1161 EFLMNWHDRLRKVEEHSVMTV------KLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLF 1214
Query: 962 EIVGYEIKPTETTCLSNMLEFGFGKFVEK---LEPIGAAASKEYSLEKNLDRMKLDWVNV 1018
++G + L L V K L+ + + A E ++ + L + L V
Sbjct: 1215 RLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGA 1274
Query: 1019 TFSFVKYRDTDTNILCAIDDIQMLLD---DHVIKTQTMCGSPFIKPIEAECRKWEEKLIR 1075
F+ + Y D+ + + I D + +++ D+ Q++ SP+ K E + WE KL
Sbjct: 1275 VFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAE 1334
Query: 1076 IQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILV 1135
+ + L Q W+YLEPIF +P+E +F VD ++S+M+ KDNR+
Sbjct: 1335 LDEYLQNLNHIQRKWVYLEPIFGR----GALPKEQTRFNRVDEDFRSIMTDIKKDNRVTT 1390
Query: 1136 AADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRV 1195
+ L L+ QK LN++LE+KR FPRF+F+ +D+LLEIL ++ +P +
Sbjct: 1391 LTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVI 1450
Query: 1196 QPHLKKCFEGIAKLEFTDNLE-IVGMISSEKETVPFIQKIYPANAKGMVEKWLQ----QV 1250
Q HLKK F GI + F + + I M S E E VPF K+ +N VE WL ++
Sbjct: 1451 QSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNN---VETWLNDLALEM 1507
Query: 1251 EQMMLASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALAENTLLDF 1310
++ + ++E + G + V + +P Q++ I +T++V A+ +++L
Sbjct: 1508 KKTLEQLLKECVTTGRSSQGAVDPS----LFPSQILCLAEQIKFTEDVENAIKDHSLHQI 1563
Query: 1311 LKKSNDQIAQIVQLVR-----GKLSSGA-RLTLGALTVIDVHARDVVAKLSEDRVSDLND 1364
+ +++ Q + G SG L L AL + +H DVV +L++ +V D
Sbjct: 1564 ETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTED 1623
Query: 1365 FQWISQLRYYWVAKDVQ-VQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNL 1423
+ W QLR+Y + VQ++ +E Y YEY GN+ +LV TPLTD+CY TL A+K+ L
Sbjct: 1624 WAWKKQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGL 1683
Query: 1424 GGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEF 1483
GG P GPAGTGKTE+ K L L +Q +VFNC +G+D K+MG+ F GL + GAW CFDEF
Sbjct: 1684 GGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEF 1743
Query: 1484 NRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNP---GYAGRAE 1540
NR+E VLS V+ QI +IQ A+ G E+ +N +FITMNP GY GR +
Sbjct: 1744 NRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQK 1803
Query: 1541 LPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYD 1600
LPDNLK LFR VAM PD LI E+ LYS GF D++ L++K+VA + L E L+ Q HYD
Sbjct: 1804 LPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYD 1863
Query: 1601 YGMRAVKSVLTAAGNLKLKYPEE------NESVLLLRALLDVNLAKFLAQDVPLFQGIIS 1654
+G+RA+K+VL +GNL + + NES ++++AL ++KF D F +I
Sbjct: 1864 WGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIK 1923
Query: 1655 DLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMG 1714
D+FPG+ L + +Y+ L ++ + +P I K +++YE + R G +IVG
Sbjct: 1924 DVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGA 1983
Query: 1715 GKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLAN 1774
GK++ +++L AAL V+ +NPKA+ QL G D + EW DGVL N
Sbjct: 1984 GKSTLWRMLRAALCKTGKV-------VKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTN 2036
Query: 1775 AFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEP 1834
+ R+ D WII DG +D WIE++N+VLDDN+ L + SGE IQ ++ +FE
Sbjct: 2037 SARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFET 2096
Query: 1835 ADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPC 1894
DL ASPAT+SR GMI++ + L S++ P+ + + D F +
Sbjct: 2097 HDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYF----EKA 2152
Query: 1895 LEFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGL 1954
L++ +VV+TS
Sbjct: 2153 LQWVLKQNDYVVETS--------------------------------------------- 2167
Query: 1955 FLFSLVWTVA-GTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDF 2013
LV TV G + + D F NLI G+ N ++ TK R S DF
Sbjct: 2168 ----LVGTVMNGLSHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDF 2223
Query: 2014 Y-----FIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETA---RQSFFLKTYL- 2064
+ + G T Y+ K+ E + A + L +P ++T R + K +L
Sbjct: 2224 HKPMDTYYDSTRGRLAT---YVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLS 2280
Query: 2065 -DHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNCINFSARTSA-------NQTQDII 2116
D + P + VGP G GK + L ++T + ++ SA+T++ +QT +I
Sbjct: 2281 SDTKQPFILVGPEGCGKGMLLRYAFSQL-RSTQIAT-VHCSAQTTSRHLLQKLSQTCMVI 2338
Query: 2117 MSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTT 2176
+ R ++ P ++ V+++ D+N+P + +G + L+Q + + ++D+ +
Sbjct: 2339 STNTGR----VYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDE-NLE 2393
Query: 2177 RLDIVDMLLVTAMGPPGG-GRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHFGKG 2235
+ + ++ +V +M G GR+ +T RFT + + SI+ E + L I+ + ++ K
Sbjct: 2394 WVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKN 2453
Query: 2236 F---------DVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVL 2286
++L G M+ + + V+++ SHY F ++ + G+
Sbjct: 2454 LKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDY------SHYFFTPCILTQWVLGLF 2507
Query: 2287 ---LCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKV 2343
L + ++ + + +E R+F D+++ ++ +F I
Sbjct: 2508 RYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLF--------------DIILT 2553
Query: 2344 LIHLSPTGKIVDDNIRSLFF---------------GDYFKPESDQKIYDEITDLKQLTVV 2388
+ G + DN+ F+ G P TDLK +
Sbjct: 2554 SVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKK 2613
Query: 2389 -MEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLS 2447
+ HY + N+ +++F +E++SRI RVL G LLL G G GR++ L
Sbjct: 2614 GLIHYGRDNQNLD-----ILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLV 2668
Query: 2448 TFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINM 2507
+ M+ L+ +I++ Y ++ DLK ++ G+ + V L D Q +F+E IN
Sbjct: 2669 SHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINS 2728
Query: 2508 LLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMS 2567
LL++G+VP ++ +E ++ ++ A G V +N+F R+ + L M
Sbjct: 2729 LLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFGPV-----FNYFTYRIQQNLHIVLIMD 2783
Query: 2568 PIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDV----ELDDNIRVEVVS 2623
F P+L C + W + W +++ + + + +D R E
Sbjct: 2784 SANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKK 2843
Query: 2624 MCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGL 2683
+ +K L + + + TP+ Y+ + + + +SK++E+ ++ G+
Sbjct: 2844 KNSVDPDFLKSFLL-IHESCKAYG-ATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGV 2901
Query: 2684 QKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEAN 2743
KL+ A + V + R+ L +E + I ++A +K ++ +
Sbjct: 2902 SKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIA 2961
Query: 2744 VAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESIC 2803
+ KN+ + +L E P + A A+ + P +S ++S++ PP ++ ++E +
Sbjct: 2962 EEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVL 3021
Query: 2804 IMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRER- 2862
+ G+ + W K L E + T+D NI + + E
Sbjct: 3022 RLMGI--------------FDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELL 3067
Query: 2863 FINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKL 2922
F N F P K S+A L WV+A Y V + + P E L +
Sbjct: 3068 FKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRK 3127
Query: 2923 NQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWT 2982
+ L V ++ L + F+ ++ LE + + + AE LI+ L E RW
Sbjct: 3128 RKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWN 3187
Query: 2983 EAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLS 3042
++ L L++ + YL A R C +W G F L
Sbjct: 3188 AQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSA------GLEKFDLR 3241
Query: 3043 HTLGDPIKIRAWQIAGLPVDSFSIDNGIIV-------SNSRRWALMIDPHGQANKWIKNM 3095
L + W+ GLP D SI+N +++ S SR +IDP QA +W+K
Sbjct: 3242 RFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTH 3301
Query: 3096 EKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPIL---LKATFKQQGV 3152
K ++L VI DSN++ LE A++ G ++I+ E+D +EP+L L+ QG
Sbjct: 3302 LKDSRLEVINQQDSNFITALELAVRFGKTLIIQ----EMDG-VEPVLYPLLRRDLVAQGP 3356
Query: 3153 EYM-RLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAA 3211
Y+ ++G+ II+Y+ +F+L+++TR NP P+ A V +NF T GL+ QLL +
Sbjct: 3357 RYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQ 3416
Query: 3212 KEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSE 3271
EKP+LEE+K +L+ + K L ++E+ +LE L+ S+GNILE++ I+ L+ +K S
Sbjct: 3417 HEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSA 3476
Query: 3272 EISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMH 3331
I E K + + +D+ R Y P+A ++ ++F ISDL+ I MY++SL F+ L+
Sbjct: 3477 LIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQR 3536
Query: 3332 SLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEE 3391
+L + SE RI+ +I +Y +CR LF+ D+L+F+L G+ E+ +E
Sbjct: 3537 ALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGM---HPELFQE 3593
Query: 3392 VWYFLLTGGIALD--------NPYPNPAPQWL-SEKAWAEIVRASALPKLHGLMEHLEQN 3442
+ TG + D + P W+ E++WA ALP L+ + ++
Sbjct: 3594 NEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTL--CFED 3651
Query: 3443 LGEWKLIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIE 3502
W+ Y+++ +E K +++++++ LRPD++ A+ F + +G +
Sbjct: 3652 AALWRTYYNNSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVS 3711
Query: 3503 APTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIA 3562
+L+ Y ++ P++ ++SP ADP L + A+ G Q +++GQGQ +A
Sbjct: 3712 PLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQ-VAMGQGQADLA 3770
Query: 3563 AKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPV 3622
+M+ ++G W+ L+N HL SW+P LEK + P+ T FRLWLT+ F
Sbjct: 3771 IQMLKECARNGDWLCLKNLHLVVSWLPVLEKEL-NTLQPKDT---FRLWLTAEVHPNFTP 3826
Query: 3623 SILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQ 3682
+LQ+ +K+T E P GL+ NL+R+Y + + +A LF L +FHA Q
Sbjct: 3827 ILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRA----HALFSLAWFHAACQ 3882
Query: 3683 ERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDK 3742
ERRN+ P GW YEF+ SDLR I + K+V ++ + L YGGR+ +
Sbjct: 3883 ERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYF 3942
Query: 3743 DRRLLLSLLSMFYCKEI-----EEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPE 3797
D R+L S L F+ + + + S+ P + +P S Y + +P P
Sbjct: 3943 DLRVLQSYLKQFFNSSVIDVFNQRNKKSIFP-YSVSLPQSCSILDYRAVIEKIPEDDKPS 4001
Query: 3798 VFGLHENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVVEELAQDILS---KLPRD 3854
FGL N + ++Q+ L L R K +E+ +L+ KL ++
Sbjct: 4002 FFGLPANIARSSQRMISSQVI-SQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQN 4060
Query: 3855 FDLEEVMKLYPVVYEESMNTVLRQELI-RFN--RLTKVVRRSLINLGRAIKGQVLMSSEL 3911
+L + + P + + +L ++ +FN RL + V +SL L + I+G L+SSE+
Sbjct: 4061 SNL--IHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEV 4118
Query: 3912 EEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPVVFW-----I 3966
+++ +++L K P W +K PL Y+ L+AR Q W+DK +
Sbjct: 4119 QKLASALLNQKCPLAWQSKWEGPEDPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDL 4177
Query: 3967 SGFYFTQSFLTGVSQNYARKYTIPIDHIGF--EFEVTPQETVMENNPEDGAYIKGLFLEG 4024
S + +FL + Q AR +D + F ++ QE ++ I GL LEG
Sbjct: 4178 SELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQ------IKISGLLLEG 4231
Query: 4025 ARWDRKTMQIGESLPKILYDPLPII--WLKPGESAMFLHQDIYVCPVYKTSARRGTLSTT 4082
+D + + + LP W+ + + PVY TSA R +
Sbjct: 4232 CSFDGNQLSENQLDSPSVSSVLPCFMGWIPQDACGPYSPDECISLPVY-TSAERDRV--- 4287
Query: 4083 GHSTNYVLSIELPTDMPQKHWINRGVA 4109
V +I++P Q WI G A
Sbjct: 4288 ------VTNIDVPCGGNQDQWIQCGAA 4308
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 924 bits (2389), Expect = 0.0
Identities = 578/1888 (30%), Positives = 952/1888 (50%), Gaps = 224/1888 (11%)
Query: 2421 RVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQV 2480
R+L ++ + +GI G G+++ A L+ ++ +LY++ I+ A +++E KK+ +
Sbjct: 2653 RLLSRELENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHA 2712
Query: 2481 GVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGEK 2540
G+ K TV + + I+ +SF+ED+N ++++G +P++F E I K++ G
Sbjct: 2713 GLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHM 2772
Query: 2541 VEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDAL 2600
S+ +FF +R+ + + MSP G +FR R++PS+I+ CTIDW++ WP +AL
Sbjct: 2773 DNRQ--SLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEAL 2830
Query: 2601 ELVANKFLED---VELDDNIRVEVVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLEL 2657
+VAN FL++ E +N++ ++ C +S+K L+ Y+ + R Y TP SYL+
Sbjct: 2831 LIVANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYLQF 2890
Query: 2658 ILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKM 2717
+ TF +L ++ +E+ R+R+ GL + A + V MQ EL L PQ+ ++ET +
Sbjct: 2891 METFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETETL 2950
Query: 2718 MVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTL 2777
M K+ +++ + ++LV+ DE+ I + + +L +PA + A+ AL+ L
Sbjct: 2951 MEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALNAL 3010
Query: 2778 NPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDL 2837
+ AD++ ++ PP V VM ++CI+ KP W +K +L +
Sbjct: 3011 DKADVAELRVYTRPPFLVLTVMNAVCILLQKKPN---------------WATAKLLLSET 3055
Query: 2838 KFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRV 2897
FL+ L DKD+IP +++ + + P+F P I VS AC LC+WV A+ Y V
Sbjct: 3056 GFLKKLINLDKDSIPDKVFVKLK-KIVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEV 3114
Query: 2898 AKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENI 2957
KVV PK+ ++ EA+ L Q+L +K+ L+LV + L L +++ +K+ L
Sbjct: 3115 QKVVGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRK 3174
Query: 2958 EICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYR 3017
+ S++ A L++ L EK RW E Q+ + + GD+LLS+ + Y G T ++R
Sbjct: 3175 TMASRRFQCASVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEFR 3234
Query: 3018 VQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRR 3077
N+W C + I S FSL + +I W GLP +S++N I++ N ++
Sbjct: 3235 QLIVNKWETFCIENGISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNGQQ 3294
Query: 3078 WALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDAS 3137
W L+IDPH QA+KWI+ ME ++L + DSNY + +ENA++ G VL++N+ E L
Sbjct: 3295 WPLLIDPHRQAHKWIRQME-GSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLAPG 3353
Query: 3138 IEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMIT 3197
++ IL K ++++G ++R+G+ EY+ +F+LY++T + NPH+LP V V ++NF +T
Sbjct: 3354 LKAILKKDIYQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFTVT 3413
Query: 3198 PLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDE 3257
GLQDQLL V E P LE+++++L+ + + L+E+E+K L +L + G+IL+D+
Sbjct: 3414 FQGLQDQLLSTVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDD 3473
Query: 3258 TAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPM 3317
+ L SK+ S EIS++ + E++I R Y P+A A ++F ++DL I M
Sbjct: 3474 KIVDTLRKSKMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYM 3533
Query: 3318 YQYSLTWFINLYMHSLTHSTKSEE-------------------------------LNLRI 3346
YQ+SL WF +++ S+ +K +E L+ I
Sbjct: 3534 YQFSLDWFHQVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHI 3593
Query: 3347 KYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKE----------ITEEVWYFL 3396
K ID T SI+ V +LF +DKL FS L IM+ + EE W
Sbjct: 3594 KSAIDMLTKSIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIF 3653
Query: 3397 LTGGIALD--------------NPYPNPAPQWLSEKAWAEIVRASA-LPKLHGLMEHLEQ 3441
L GI ++ + QWLS+ W + S L L + L
Sbjct: 3654 LYSGILINIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSLLS 3713
Query: 3442 NLGEW------KLIY----------------DSAWPHEEQLPGS-----------WKFSQ 3468
N+ +W K +Y ++ P E +L W+
Sbjct: 3714 NVSQWDTFKNSKAVYSLISTPFSSENASLEENTKPPEETELLNENKETCNPINFPWEKLT 3773
Query: 3469 GLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPS 3528
+++++++ LRP+ + +VR+FI E MG Y++ +L+ +Y S+ PLI + +
Sbjct: 3774 SFQRLILVKVLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQTHG 3833
Query: 3529 ADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAI-KDGTWVVLQNCHLAASW 3587
D LL+FA +L ISLG+ Q A +I A+ K WV LQNCHLA S+
Sbjct: 3834 IDLTNILLRFAQELKGTTHHVTIISLGRDQAAKAEDLILKALTKTQQWVFLQNCHLATSF 3893
Query: 3588 MPTLEKICEEVIVPEST-NARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRS 3646
MP L I E P T + FRLWL+S FP+ +L+ G+K+ E P+GL++NLL++
Sbjct: 3894 MPRLCTIVESFNSPNVTIDPEFRLWLSSKSYSSFPIPVLKKGLKIAVESPQGLKSNLLQT 3953
Query: 3647 Y---LNDPISDPVFFQ-SCAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESD 3702
+ + +++ +F C + W+K+LF LCFF+AV+ ER+N+G LGWNI Y+FN SD
Sbjct: 3954 FGCTGSGEVTEEIFENPDCGQ--WWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSSD 4011
Query: 3703 LRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEED 3762
L +++ ++ L + + AL YL GE YGGRV D+ D+R L +LL F E+ +D
Sbjct: 4012 LGVAIKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPEVLKD 4071
Query: 3763 YYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVL 3822
+S + S + YI +++LP PEV G+H A + + + E ++
Sbjct: 4072 DFSFSRS--------ASIKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIENLI 4123
Query: 3823 LTLPRQSGGS-----GKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMN---- 3873
P+ + + +S E+V E+ D+L +LP + EE+ P + M+
Sbjct: 4124 AMQPKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIAVGTPSTLKSMMSSSIW 4183
Query: 3874 -------------------TVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEV 3914
T L+QE+ RF++L V+ +SL +L AIKG+++++ ELEE+
Sbjct: 4184 ESLSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAIKGEIILTQELEEI 4243
Query: 3915 FNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWID----------------- 3957
FNS L +VP +W +Y S KPL ++ DL+ RL FF W
Sbjct: 4244 FNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVAYTAIQRRYMRFVTVW 4303
Query: 3958 ----------------------KGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIG 3995
+G P +W+ F+F Q+FL V Q+Y R I +D +
Sbjct: 4304 KQSIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSRGIAVDALT 4363
Query: 3996 FEFEVTPQETVMEN---------------------NPEDGAYIKGLFLEGARWDRKTMQI 4034
F V T + + G YI GLF+EGARW+R+ +
Sbjct: 4364 FTHHVISNTTDKDEKFSVFMPKKLNIVRRAFKGSASSHTGVYIFGLFIEGARWNREQKIL 4423
Query: 4035 GESLPKILYDPLPIIWLKPGE-------SAMFLHQDIYV--CPVYKTSARRGTLSTTGHS 4085
+SLP + P I+ P + ++ ++Y CPVY+T R L+TTG
Sbjct: 4424 EDSLPLEMCCDFPDIYFLPTKISTKTPNASNQTDSELYAFECPVYQTPERSRILATTGLP 4483
Query: 4086 TNYVLSIELPTDMPQKHWINRGVASLCQ 4113
TN++ S+ L T P HWI VA LC+
Sbjct: 4484 TNFLTSVYLSTKKPPSHWITMRVALLCE 4511
Score = 685 bits (1767), Expect = 0.0
Identities = 456/1376 (33%), Positives = 684/1376 (49%), Gaps = 182/1376 (13%)
Query: 870 EQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAEN 929
++LW E+ S EW N L ++ E + + + +I L + +
Sbjct: 1000 KKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMH----IISVLEKGLPKSDMVTH 1055
Query: 930 VKIKIDKFKQYIPILSISCNPGMKDRHWQQISEIVGYEIKPTETTCLSNMLEFGFGKFVE 989
+K + +FKQ +PI+ NP +K RHW+ + EI+G + + + N+L ++
Sbjct: 1056 LKQVVTEFKQELPIIIALGNPCLKPRHWEALQEIIGKSVPLDKNCKVENLLALKMFQYEN 1115
Query: 990 KLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVKYRDTDTN---ILCAIDDIQMLLDDH 1046
++ + +A+ E +LEK L ++ +D+ N T + T+ I+ +IDDI L++
Sbjct: 1116 EINDMSTSATNEAALEKMLFKI-IDFWNTTPLPLILHHTEIYSIFIIPSIDDISAQLEES 1174
Query: 1047 VIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIFSSEDIIAQM 1106
+ T+ GSP I PI+ +W++ L L+ W+ CQ WLYLEP+F S +I Q+
Sbjct: 1175 QVILATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEEWMNCQRNWLYLEPVFHSSEIRRQL 1234
Query: 1107 PEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEK 1166
P E F V S WK +MS+ L + E LQ N LE I+K L DYLE
Sbjct: 1235 PAETELFSQVISMWKKIMSKIQNKQNALQITTSAGVLEILQNCNIHLEHIKKSLEDYLEV 1294
Query: 1167 KRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKKCFEGIAKL----EFTDNLEIVGMIS 1222
KRL FPRF+FLSN ELL+IL+++++P VQPHL KCFE I +L + + +IS
Sbjct: 1295 KRLIFPRFYFLSNAELLDILADSRNPESVQPHLVKCFENIKQLLIWKQDIGPPAVKMLIS 1354
Query: 1223 SEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRNHWVLQWP 1282
+E E + +KI + VE+WL VE+ M +++ E Y+ + +L +
Sbjct: 1355 AEGEGLVLPKKI---RVRSAVEQWLVNVEKSMFDVLKK------ERYIY----NIILLFQ 1401
Query: 1283 GQVVI---CVSSIF--WTQEVSQALAENTLLDFLKKSNDQIAQIVQLVRGKLSSGARLTL 1337
Q++ CV S +++E + + + +++A +V L +S + L
Sbjct: 1402 SQIMFYNDCVKSFVSSYSREKLEKVHAGLMCHL-----EEVADLVVLDTS--NSRTKAIL 1454
Query: 1338 GALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDVQVQIITTEA--LYGYEY 1395
GAL ++ VH RD+V L + + DF+W L+Y W K + A YGYEY
Sbjct: 1455 GALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQGNASFTYGYEY 1514
Query: 1396 LGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNC 1455
LG + RLVITPLTDRC+ TLM AL LNLGG P GPAGTGKTET KDLAK+L K CVVFNC
Sbjct: 1515 LGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKSLGKHCVVFNC 1574
Query: 1456 SDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFE 1515
+ LDYK + KFF GL Q+GAW+CFDEFN I++EVLSV+A QIL+I+ A F+ E
Sbjct: 1575 FEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILTIKAAKDNYSARFVLE 1634
Query: 1516 GTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDS 1575
G E+ +N +CAVFITMNP Y G ELPDNLK+LFR VAMMVP Y +I EI L+S GF +
Sbjct: 1635 GKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILFSFGFKSA 1694
Query: 1576 RSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKY---PEENESVLLLRA 1632
SL+ K+ Y L +QLS Q HY++G+R++K VL AG K ++ E +E+++++ A
Sbjct: 1695 NSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFKCLSEADETLIVIEA 1754
Query: 1633 LLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGK 1692
+ + +L K +DVPLF+ II D+FP V + K + KV+ +++ LQ K
Sbjct: 1755 IREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLGLQNWSSQKEK 1814
Query: 1693 IIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAAL-----------GDLHAANQMEE--F 1739
IIQ Y + V G M+VG GGKT+ ++L AL + +A+++ E
Sbjct: 1815 IIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAERKSASKISERKG 1874
Query: 1740 AVEYKIINPKAITMGQLYGCFDQVSHEWMDGV---------------------------- 1771
V+ ++NPK +T+ +LYG D + EW DG+
Sbjct: 1875 KVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTKKDIDLRLKSR 1934
Query: 1772 ---LANAFREQASSLSD---------------------DRKWIIFDGPVDAIWIENMNTV 1807
L+N F+ +S ++ D +WII DGPVD W+EN+N+V
Sbjct: 1935 ISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPVDTFWVENLNSV 1994
Query: 1808 LDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSY 1867
LDD + LCL + E I + +K+ +IFE +L QASPATVSRC M+YM+P LGW+P S+
Sbjct: 1995 LDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVDLGWEPYVKSW 2054
Query: 1868 MDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKF-VVQTSPIHLAFSMMRLYSSLLD 1926
+ +++ + + M V L+F R KF I + ++ R+ + D
Sbjct: 2055 LLKTSKIISQSGVDCLEFMIKNSVTDGLQFIRNRQKFQPYPMEDITVVITLCRILDAFFD 2114
Query: 1927 EI------------------RAVEEEEMELGEGLSSQQIFLW------------LQGLFL 1956
+ A + E + + + W +Q LF+
Sbjct: 2115 FMGKNGGFEQSDDLNDTSSKEANSQRESVTFKDIEKRDENTWYPEKNPDKLTKIIQKLFV 2174
Query: 1957 FSLVWTVAGTIN----------------ADSRKKFDVFFRNLIMGMDDN-------HPRP 1993
F+ W G +N DS K F L+ + N H
Sbjct: 2175 FAFTWAFGGALNREDEHRENIPFCPSLEPDSLAKVTYDFDKLVHELFGNSSQVGWKHWGQ 2234
Query: 1994 KSVKLTKNNI--FPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAGA---------- 2041
+ K N P YF+ + W+ + ++ + G
Sbjct: 2235 SQGRRRKGNCINLPTGECSIFGYFVDIEQCEFIPWSDLVPNDQTLIQRGTSLLTNLQRSG 2294
Query: 2042 ----KVSEL-----IIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFL 2088
K++E T +T SF + L + P+L G +G GK+A N L
Sbjct: 2295 GNFLKITECGECINYTATRDTTCLSFLMSLLLKNSCPVLLTGESGVGKTAAINQML 2350
Score = 168 bits (425), Expect = 1e-40
Identities = 104/346 (30%), Positives = 175/346 (50%), Gaps = 19/346 (5%)
Query: 2101 INFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELL 2160
INFS +A +T+++I+ KL RR K G P + ++F+DD+NMP ++YGAQPP+EL+
Sbjct: 2430 INFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPPLELI 2489
Query: 2161 RQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDIL 2220
RQ +D G +D + T +I D+ +V A P NDI+ R +H +++ + DIL
Sbjct: 2490 RQLLDLGGVYDTEKNTWKNIQDLSIVAACVPV---VNDISPRLLKHFSMLVLPHPSQDIL 2546
Query: 2221 TKIFSSIVDWHFG-KGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFS 2279
IF + + +F F + ++ + IY +N LPTP+K HY+FNLRD
Sbjct: 2547 CTIFQAHLGIYFSINNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPTKCHYMFNLRDMF 2606
Query: 2280 RVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCF--- 2336
+++ G+L T + E L++HE RVF+DRLID D+ +F+ ++ NCF
Sbjct: 2607 KLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYRLLSRELENCFQIG 2666
Query: 2337 -----KQTIEKVLIHLSPTGKI---VDDNIRSLFFGDYFKP---ESDQKIYDEITDLKQL 2385
K+T + +L+ + + F + FK + K + + L
Sbjct: 2667 IDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHAGLKGKPTVLMVPNL 2726
Query: 2386 TVVMEHYLEEFNN-ISKAPMSLVMFRFAIEHISRICRVLKQDKGHL 2430
+ + +LE+ N IS + + ++ I+ R L + GH+
Sbjct: 2727 NIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHM 2772
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 484 bits (1246), Expect = e-136
Identities = 292/819 (35%), Positives = 439/819 (53%), Gaps = 33/819 (4%)
Query: 3308 ISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFE 3367
++DL+ I PMYQ+SL F ++ ++ + E L R+ +ID T S+Y R LFE
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3368 KDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPYPNPAPQWLSEKAWAEIVRAS 3427
DKL + LT I+ +E+ FLL + P ++LS +AW + S
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASP---VEFLSHQAWGAVKVLS 117
Query: 3428 ALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPA 3487
++ + L +E + WK +S P +E+LP WK L+++ +LR +RPD+M A
Sbjct: 118 SMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYA 177
Query: 3488 VREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLG--MG 3545
+R+F+ E +G Y+ D S+ +S P+ F+LSP DP+ + LG
Sbjct: 178 LRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFN 237
Query: 3546 GTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTN 3605
+SLGQGQ +A ++ A K G WV+LQN HL A W+ TLEK EE E+++
Sbjct: 238 NQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEH--SENSH 295
Query: 3606 ARFRLWLTSYPSEK-----FPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQS 3660
FR+++++ P+ P IL+N IK+TNEPP G+ ANL ++ L++ D + +
Sbjct: 296 PEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKA-LDNFTQDTL--EM 352
Query: 3661 CAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEV 3720
C++ ++ +LF LC+FHAVV ERR FGP GWN Y FN DL IS+ + FL +V
Sbjct: 353 CSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKV 412
Query: 3721 PFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSY 3780
P+D L YL GE YGG +TDD DRRL + L F E+ E SLAPG + +P + Y
Sbjct: 413 PYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPG--FPLPGNMDY 470
Query: 3781 QSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQS---GGSGKSPQ 3837
Y Y+ P ++GLH NA+I Q + +LF VL PR S G+G + +
Sbjct: 471 NGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATRE 530
Query: 3838 EVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINL 3897
E V+ L ++IL ++ +F++ E+M V V QE R N LT+ ++RSL L
Sbjct: 531 EKVKALLEEILERVTDEFNIPELMA--KVEERTPYIVVAFQECGRMNILTREIQRSLREL 588
Query: 3898 GRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWI- 3956
+KG++ M+S +E + N++ VP WA ++YPS L + DLL R+ + W
Sbjct: 589 ELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTG 648
Query: 3957 DKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQ-ETVMENNPEDGA 4015
D P W++GF+ QSFLT + Q+ ARK P+D + + ++T + + P +GA
Sbjct: 649 DFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGA 708
Query: 4016 YIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSAR 4075
YI GLF+EGA WD + I E+ K L P+P++++K + + +Y CPVYKTS R
Sbjct: 709 YIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR 768
Query: 4076 RGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQL 4114
T YV + L T W+ GVA L Q+
Sbjct: 769 GPT---------YVWTFNLKTKENPSKWVLAGVALLLQI 798
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 258 bits (658), Expect = 1e-67
Identities = 360/1749 (20%), Positives = 675/1749 (38%), Gaps = 289/1749 (16%)
Query: 815 TEEMKHNVEKLNELSKNLNRAFAEFELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWS 874
T++ + +L L + ++ ++ + ++++ PL + V +++W
Sbjct: 964 TQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQQRIWH 1023
Query: 875 TAYEFSIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKI 934
S EW F + +A+E W T + T ++ +P + ++ +
Sbjct: 1024 LYRVISENISEW-KCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSP--VLQHCMRIL 1080
Query: 935 DKFKQYIPILSISCNPGMKDRHWQQISEIVGY-EIKPTETTCLSNMLEFGFGKFVEKLEP 993
+F+ Y+P+L+ + + + Q + +G ++ E L +L + +F +++
Sbjct: 1081 GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQ 1140
Query: 994 IGAAASKEYSLEKNLDRMKLDWVNVTFSFVKY---------------------------- 1025
+ ++ ++ + R++ W + +
Sbjct: 1141 VWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVD 1200
Query: 1026 RDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLK 1085
+D+ T IL ++Q + + + + + +W + + L+ WL
Sbjct: 1201 KDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLT 1260
Query: 1086 CQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILV-----AADQP 1140
Q W++L + I + +F ++D +++LM +V D +L A P
Sbjct: 1261 FQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSP 1320
Query: 1141 -----RMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRV 1195
++ + LQ + LE I L L FPR FFLS+ EL+ +L+ +
Sbjct: 1321 YFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEA 1380
Query: 1196 QPHLKKCFEGIAKLEF---------TDNLEIVGMISSEKETVPF-------IQKIYPANA 1239
Q +++CF + + F TD+ E ++ E + ++ P
Sbjct: 1381 QLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPL 1440
Query: 1240 KGMVEKWLQQVEQMMLASMREVI------------GLGIEAYVKVPR----------NHW 1277
+ KWL +E+ + ++ ++ LG EA ++P+ HW
Sbjct: 1441 HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLG-EALKQLPKQNKLYLQLYVQHW 1499
Query: 1278 ---VLQWPGQVVICVSSIFWTQEVSQALAENTLLDFLKKSNDQIAQIVQLVRGKLSS--- 1331
V +P Q V+ + W E+ +AL E L + ++ +V +R + +S
Sbjct: 1500 IDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMHMRKLEVLVNFMRAQRASQGG 1559
Query: 1332 ----GARLT--LGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDV----- 1380
R T L AL V+ V RD+ L + +VSDL DF W+ QL+Y+ + +
Sbjct: 1560 QSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSP 1619
Query: 1381 -------------------QVQIITTEALYGYEYLGNSPRLVITP--LTDRCYRTLMGAL 1419
+ ++ LY YEYLG PRL P L +R L+ AL
Sbjct: 1620 LQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLAL 1677
Query: 1420 KLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWAC 1479
+ G GP G GK LA+AL +Q V+ CS ++ + + + G Q GAW
Sbjct: 1678 EEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLL 1737
Query: 1480 FDEFNRIEVEVLSVVAQQI-------LSIQQAIIRKLKTF-----------IFEGTELSL 1521
++ +++ +LS + Q++ + Q R T FE +S+
Sbjct: 1738 LEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSV 1797
Query: 1522 NPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQK 1581
+ + A + +P NL L R VA+ +PD + E++L G D+ +A +
Sbjct: 1798 RLGYGCLLVLR---ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATR 1854
Query: 1582 IVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKF 1641
+ + L E +S + +K +L L +E R+L + A
Sbjct: 1855 LSKFFSLERELVSGP--LPCRLPLLKQILEDTIR-TLNVTKEEPKCQKPRSLAAIEEAAL 1911
Query: 1642 LAQDVPLF-----------QGIISDLFPGV--VLPKP-DYEVFLKVLNDNIKKMKLQPVP 1687
L PLF +G++ LFP VL +P Y++ ++ + ++++ L P P
Sbjct: 1912 LRS--PLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSP 1969
Query: 1688 WFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFA------V 1741
+G + Q+ + + G +++G GKT+ + L L A ME+ + V
Sbjct: 1970 DILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAA---MEDTSTQGCQPV 2026
Query: 1742 EYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFRE--QASSLSDDRK---------WI 1790
E + P ++ + G + W G+ R Q +++ R+ WI
Sbjct: 2027 EITHLYPSGLSPQEFLGWLE--GSCWHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWI 2084
Query: 1791 IFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGM 1850
I DG + W++++ +L + +L L SG+ I L+ E AD SP V C +
Sbjct: 2085 ICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCAL 2144
Query: 1851 IYMEPHQLGWKPLKDSYMDTLPSSLTKEHKEL--VNDMFMWLVQPCLEFGRLHCKFVVQT 1908
++ Q W+ + + M +LP +H+ + +N M LV L F L C+ V
Sbjct: 2145 VWCGGEQT-WQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRF--LTCQGVSSL 2201
Query: 1909 SPIH----------LAFSMMRLYSSLLDEIRAVEEEEMELGEGL-----------SSQQI 1947
+H SM R+ SLLD ++EE+ E L SS+
Sbjct: 2202 LQVHGQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSS 2261
Query: 1948 F------------------LWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDN 1989
F L FLF+L+W + + FD F R+ I + +
Sbjct: 2262 FLNRSQVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNY 2321
Query: 1990 HPRPKSVKLTKNNIFPERGSIYDF---YFIKQASGHWETWTQYITKEEEKVPAGAKVSEL 2046
P S + ++ PE G++ F Y G T+
Sbjct: 2322 PEPPPSALVFDLHVSPEDGTLVPFTGQYLSSHIKGTLGTFH------------------- 2362
Query: 2047 IIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNCINFSAR 2106
P+++T R + + L P+L G TGKSA +L P + Y+ + I+
Sbjct: 2363 --PSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVE--VLVEPHHPYIYSPIH--PA 2416
Query: 2107 TSANQTQDIIMSKLDRRRKGLFGP---PIGKKAVVF-VDDLNMPAKE-VYGAQPPIELLR 2161
S++ + ++ + + + P K +++F ++DL++ + QP +E LR
Sbjct: 2417 FSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLETLR 2476
Query: 2162 QWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILT 2221
Q +D + + + + + PG + R R ++++ + L
Sbjct: 2477 QAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESMTQATLL 2536
Query: 2222 KIFSSIVDWHFGKGFDVMFLR-YGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSR 2280
+ I+ + V R + LV+A+ + F+P+P HY F+L S
Sbjct: 2537 ERHVPIIQAWLERFPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSH 2596
Query: 2281 VIQGVLLCPH--------------THLQDV--------------EKCIRLWIHEVYRVFY 2312
++ + L P+ HL+ V +RLW+HE R F
Sbjct: 2597 LLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFC 2656
Query: 2313 DRLIDKEDR 2321
DRL +R
Sbjct: 2657 DRLDSPRER 2665
Score = 127 bits (320), Expect = 2e-28
Identities = 245/1134 (21%), Positives = 422/1134 (37%), Gaps = 178/1134 (15%)
Query: 3101 LAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGEN 3160
L+V+ +D L+ A G PVL+ N+ EL E + +Q ++ G
Sbjct: 3664 LSVLSGADPELGSQLQEAAACGLPVLLTNV--ELGLGCEELQWLLQREQLSPPQVQPG-- 3719
Query: 3161 IIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGL-----QDQLLGIVAAKEKP 3215
F LY++T L + + +V L + LGL ++Q+L + +E P
Sbjct: 3720 -------FCLYLSTTL-SLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYP 3771
Query: 3216 ELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIK-------VLSSSKV 3268
ELE + L + + K ++ E+++L +L + ++ L +
Sbjct: 3772 ELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRA 3831
Query: 3269 LSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINL 3328
EE+ E QK+ M Y+PV H + +S L N+ P++ S ++ +
Sbjct: 3832 HCEEL-EGQKLQEMV------LWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAV 3884
Query: 3329 YMHSLTHSTKSEELN------LRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIM 3382
+L S K E+N + + H T + + +L L L + ++
Sbjct: 3885 TKQALD-SMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALL 3943
Query: 3383 KQKKEITE----EVWYFLLTGGIALDN-PYPNPA-PQWLSEKAWAEIVRASALPKLHGLM 3436
+ + +E +W L + + P + A P WL KAW E LP GL
Sbjct: 3944 QATGKASELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLC 4003
Query: 3437 EHLEQNLGEWK--LIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAE 3494
L + W+ L S PG S L+K+++ R LRP+ + A+ +F
Sbjct: 4004 ASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSL-LQKLILWRVLRPECLAGALADFTTS 4062
Query: 3495 HMGKLYIE---APTFDLQGSYNDSSCCAPLIFVLSPSADPMAGL------LKFADDLGMG 3545
+G+ E APT + S P++ +L P P A L K A G
Sbjct: 4063 LLGRPLDENTYAPTMP----FKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQG 4118
Query: 3546 GTRTQTISLG-QGQGPIAAKM--INNAIKDGTWVVLQNCHLAASWMPTLEKICEEVI--- 3599
+ Q I+LG + P++ + ++ A+ +G W+VL NCHL W L ++ E++
Sbjct: 4119 QKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRA 4178
Query: 3600 -------------VPESTNAR-----FRLWL--TSYPSEKFPVSILQNGIKMTNEPPKGL 3639
PES N FRLWL + S P + Q+ + + L
Sbjct: 4179 KVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLEL 4238
Query: 3640 RANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFN 3699
L+ S ++ V + + +L GL + R W+ +
Sbjct: 4239 GHVLIDSV---ELAQQVLYMQPPTQALPLLLLHGLLLHRQLYGTRLQAHRGRWS---QVT 4292
Query: 3700 ESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEI 3759
+ + + Q+ L++ P A+ L YGG + D +DR L+SL
Sbjct: 4293 LTQVLQTQDQLWASLSN----PRAAMQELAASVFYGGPLGDTEDREALISLTQA------ 4342
Query: 3760 EEDYYSLAPGDTYYIPPHGSYQSYIDYL-------------------RNLPITAHPEVFG 3800
L+P ++ PH + QS + L LP P + G
Sbjct: 4343 -----CLSPSSGSWVQPH-TPQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCG 4396
Query: 3801 LHENADITKDNQETNQLFEGVL----LTLPRQSGGSGKSPQEVVEELA---------QDI 3847
L E +++ L + + +P G+ + + + + L QD+
Sbjct: 4397 LSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQVNRRLESLQDL 4456
Query: 3848 LSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKG-QVL 3906
L+ + R + + + + VL E + ++L ++R L L + +KG
Sbjct: 4457 LTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPC 4516
Query: 3907 MSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKG------- 3959
S V +++ G++P W + +P ++ L R ++ G
Sbjct: 4517 PSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDV 4576
Query: 3960 PPVVFWISGFYFTQSFLTGVSQNYARKYTIP--------------IDHIGFEFEVTPQET 4005
P VF +S F + L + A +P + + E P
Sbjct: 4577 PERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLHF 4636
Query: 4006 VMENNPEDGAYIKGLFLEG-----ARWDRKTMQIGESLPKILYDPLPIIWLK---PGESA 4057
+EN P +GL L G A WD + +S P PLP + + PG S
Sbjct: 4637 RVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDS-PSSQPSPLPPVSISTQAPGTSD 4695
Query: 4058 MFLHQD--IYVCPVYKTSARRGTLSTTG-HSTNYVLSIELPTDMPQKHWINRGV 4108
+ D +Y CPVY G L T S N V+ + LPT + + R V
Sbjct: 4696 LPAPADLTVYSCPVY----MGGPLGTAKLQSRNIVMHLPLPTKLTPNTCVQRRV 4745
Score = 83.6 bits (205), Expect = 4e-15
Identities = 145/732 (19%), Positives = 275/732 (37%), Gaps = 88/732 (12%)
Query: 2414 EHISRICRVLKQDKGH-LLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWRED 2472
+H++R+ RVL + + H LLL G G+GR +A L++ + + + A +
Sbjct: 2870 QHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEA---ILQC 2926
Query: 2473 LKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQT 2532
L+ G+ ++ L D + + + L +G P + + I E +
Sbjct: 2927 LRDASWHAGMLSQPVALLVPSGV--DLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPR 2984
Query: 2533 AARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRL---RMFPSLINCCT- 2588
G K + + F ++V + + IGD ++ +F L+ T
Sbjct: 2985 --ENLGVKQNIKKEMVLQRFHQQVCSHLHLFFL---IGDKQAHKQLPSTLFLRLLQLATA 3039
Query: 2589 -IDWFQSWPTDALELVANKFLE---DVELDD------NIRVEVVSMCKYFQESVKKLSLD 2638
ID ++ W AL VA LE V LDD +++ + S+ K ++ LS
Sbjct: 3040 SIDRYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAM--ALIHLSAT 3097
Query: 2639 YYNK--LRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVM 2696
+Y++ VTP ++L+ + TF L ++ R L+ L +
Sbjct: 3098 HYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTH 3157
Query: 2697 QRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNEC 2756
+ L+ QL +++ K + + + ++ KLL + +E + + + +
Sbjct: 3158 ANLIFDLEQQL----KDSGKSLSMFQQQLEQS---KLLYKQQLEECRHQENLIENLARQR 3210
Query: 2757 EGDLAEAMPALE----AALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPER 2812
+ A+ LE A L L L AD ++S + PP V V +++C +
Sbjct: 3211 DALQAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHH---- 3266
Query: 2813 KPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPA 2872
E W +K++L F + L + K+ I + ++ + P A
Sbjct: 3267 -----------ETGWASAKQLLCTEDFYQELVFFPKEKITDSELIKLH-LILKAPGMDDA 3314
Query: 2873 VIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLV 2932
++ VS L W+ A+ Y P L++ E L + +L + + +
Sbjct: 3315 ALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQET 3374
Query: 2933 VDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRY 2992
++ AL E+ + + + + + L WT ++L R
Sbjct: 3375 LEHNLALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPMRAWTTQLQKLKGRC 3434
Query: 2993 TNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAEC------------------------ 3028
+ GD LL S + YLG F R + ++WLA C
Sbjct: 3435 MTVFGDTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVS 3494
Query: 3029 ---KDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVS-----NSRRWAL 3080
K+ ++ S FS+ L + W P + G+++ +S RW L
Sbjct: 3495 IPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPL 3554
Query: 3081 MIDPHGQANKWI 3092
++DP +A W+
Sbjct: 3555 LLDPSNEALIWL 3566
>gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens]
Length = 457
Score = 85.1 bits (209), Expect = 1e-15
Identities = 90/413 (21%), Positives = 169/413 (40%), Gaps = 64/413 (15%)
Query: 235 YYYLTNGIRKDMIAPEEGEVMVRISKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKS 294
Y Y+ + + P + E + + +LI +L E L+ L+ E +D+ S+ +
Sbjct: 96 YIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRY 155
Query: 295 IVDYILMDPMERKRLFIESIPRLFPQRVIRAPV--PWHSVYRSAKKWNEEHLHTVNPMML 352
+V +L+ P + +E P+ + PWHS Y A+ +LH ++P M
Sbjct: 156 LVQSVLVKPPVKS---LEDEGGPLPESPVGLDYSNPWHSSYVQARNQIFSNLHIIHPTMK 212
Query: 353 RLKELWFAEFRDLRFVRTAEILAGKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLF 412
L +L + F D + I A K P+ + + A + ++N W P LF
Sbjct: 213 MLLDLGYTTFADTVLLDFTGIRA-KGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLF 271
Query: 413 TSRKEHWIHFAPKSNYDSSRNIEEYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGND 472
T +KE P+ ++ +++ V++ MS QL++L+ +++E V LF
Sbjct: 272 T-KKEALEGVKPE-------KLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF-------- 315
Query: 473 FKEPYQEMKFFIPQLIMIKLEVSEPIIVFNPSFDGCWELIRDSFLEIIKN-SNGIPKLKY 531
+P + + + I+L + + F P+F + D+ L +++ + + ++
Sbjct: 316 --DPKDQQRL---PIFKIELTFDDDKMEFYPTFQD----LEDNVLSLVERIAEALQNVQT 366
Query: 532 IPLKFSFTAAAADRQCVKAAEPGEPSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQ 591
IP S T+ + E H A+ LK
Sbjct: 367 IPSWLSGTSTPVNLDT-------ELPEHVLHWAVDTLKA--------------------- 398
Query: 592 TFKVFQKNQVGPCKYLNVY-KKYVDLLDNTAEQNIAAFLKENHDIDDFVTKIN 643
+N G K+ Y +KY LLD TA +NI F E+H D++ +++
Sbjct: 399 ---AVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFDEYTEELD 448
>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
[Homo sapiens]
Length = 1005
Score = 45.4 bits (106), Expect = 0.001
Identities = 31/105 (29%), Positives = 57/105 (54%), Gaps = 8/105 (7%)
Query: 2906 ERLREAEGKLAAQMQKLNQKRAELKLVVDRL------QALNDDFEEMNTKKKDLEENIEI 2959
++L+ + +LA+ ++L +K +E+K + ++L + + + N KKK E+NIE+
Sbjct: 226 KKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEV 285
Query: 2960 CSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSG 3004
QK+ +A + + EKDR E RQ RY + V+L+ G
Sbjct: 286 --QKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQG 328
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 42.4 bits (98), Expect = 0.010
Identities = 56/269 (20%), Positives = 120/269 (44%), Gaps = 42/269 (15%)
Query: 676 CERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSLIEFLKKSSA- 734
CER H ++ + +NR++ ++ + H+A+++ + ++ S +E K A
Sbjct: 1060 CEREL----HKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQ 1115
Query: 735 --VTVFKLRRQLRDASERLE--------FLMDYADLPYQIEDIFDNSRNLLLHKRDQAEM 784
TV +L+ Q++D E+LE + ADL + D+ N R + A++
Sbjct: 1116 LQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADL--NERLEEVGGSSLAQL 1173
Query: 785 DLIKRCSEFELRLEGYHRELE-----------SFRKREVMTTEEMKHNVEKLNELSKNLN 833
++ K+ E + + HR++E S +KR + E++ VE L ++ + L
Sbjct: 1174 EITKK---QETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLE 1230
Query: 834 RAFAEFELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFL 893
+ ++ +L + ++LL + ++ M + K E+L T YE + +
Sbjct: 1231 KDKSDLQL--EVDDLLTR-------VEQMTRAKANAEKL-CTLYEERLHEATAKLDKVTQ 1280
Query: 894 LNAEQIAEEIGNMWRTTYKLIKTLSDVPA 922
L A +A + +W + + ++ L + A
Sbjct: 1281 L-ANDLAAQKTKLWSESGEFLRRLEEKEA 1308
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 41.6 bits (96), Expect = 0.016
Identities = 79/420 (18%), Positives = 165/420 (39%), Gaps = 57/420 (13%)
Query: 2604 ANKFLEDVELDDNIRVEVVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYL-------- 2655
A + +D+E + + +VE++ + ++ +KKL +Y + + N SY
Sbjct: 566 AEVYNQDLENELSSKVELL---REKEDQIKKLQ-EYIDSQKLENIKMDLSYSLESIEDPK 621
Query: 2656 ---ELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSE 2712
+ + +T+ ++E A +R+ L +K+ A+ M+ ++ Q QL E
Sbjct: 622 QMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQL----E 677
Query: 2713 ETAKMMVKIEAETREADGK--KLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAA 2770
KM V +E E + A + KL D K E EG + + L
Sbjct: 678 AKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLC-----NLELEGKITDLQKELNKE 732
Query: 2771 LAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSGKMIEDYWGVS 2830
+ + L ++ L+ +++ P V+ + + I + E S K+ +
Sbjct: 733 VEENEALRE-EVILLSELKSLPSEVERLRKEI---QDKSEELHIITSEKDKLFSEVVHKE 788
Query: 2831 KKILGDLKFLESLKTYDKDNIPPLTMKRIRERFIN----HPEFQPAVIKNVSSACEGLCK 2886
++ G L+ E KT D K + F N H +F+ K
Sbjct: 789 SRVQGLLE--EIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQ--------------K 832
Query: 2887 WVRAMEVYDRVAKVVAPKRERLREAEGKLAA-------QMQKLNQKRAELKLVVDRLQAL 2939
+ +E +R+ + + + ++ + L A + Q+L +K E++ ++ ++ L
Sbjct: 833 YKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQL 892
Query: 2940 NDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDV 2999
+ E ++ + +E + ++KL + + + L EKD + L I L D+
Sbjct: 893 KEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDI 952
Score = 38.1 bits (87), Expect = 0.18
Identities = 64/329 (19%), Positives = 136/329 (41%), Gaps = 50/329 (15%)
Query: 567 ELKGYNLLLGTVNAEEKLVSDFLIQTFKVFQKNQVGPCKYLNVYKKYVDLLDNTAEQNIA 626
+L+ + L TV E+ L+++ L QT + K L K + L + +
Sbjct: 895 QLENRDSTLQTVEREKTLITEKLQQTLE--------EVKTLTQEKDDLKQLQESLQIERD 946
Query: 627 AFLKENHD-----IDDFVTKINAIKKRRNEIASMNITVPLAMFCLDATALNHDLCERAQN 681
+ HD ID NA++ + ++N L + + N + E
Sbjct: 947 QLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINT---LKSKISEEVSRNLHMEENTGE 1003
Query: 682 LKDHLIQFQVDVNRDTNTSICNQYSHIAD-KVSEVPANTKELVSLIEFLKKSSAV--TVF 738
KD Q V +++ + N + AD K +E+ +++ SLI+ + + +V
Sbjct: 1004 TKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVI 1063
Query: 739 KLRRQLR-DASERLEFLMDYADLPYQIEDIFDNSRNLLLHKRDQA---EMDLIKRC---S 791
+ QL+ D E +E ++ + + D + ++ +++ A E +L + C +
Sbjct: 1064 AEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLA 1123
Query: 792 EFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNE------------------------ 827
E E +L+ ++L+ +++ + EEM +K+NE
Sbjct: 1124 EVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLE 1183
Query: 828 LSKNLNRAFAEFELINKEEELLEKEKSTY 856
L++ LN + E + I KE ++L++ + ++
Sbjct: 1184 LAQKLNENYEEVKSITKERKVLKELQKSF 1212
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 40.8 bits (94), Expect = 0.028
Identities = 90/395 (22%), Positives = 159/395 (40%), Gaps = 61/395 (15%)
Query: 1471 LAQA---GAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAV 1527
LAQA G W DE N E+L ++ + +++ + + L +P +
Sbjct: 823 LAQAVKKGEWILLDEINLAAPEILECLSGLLEGSSGSLVLLDRG---DTEPLVRHPDFRL 879
Query: 1528 FITMNPGY-AGRAELPDNLKALFRT--VAMMVPDYALIGEISLYSMGFLDSRSLAQKIVA 1584
F MNP G+ LP ++ F V + L I Y G +++ Q I+
Sbjct: 880 FACMNPATDVGKRNLPPGIRNRFTELYVEELESKEDLQVLIVDYLKGLSVNKNTVQGIIN 939
Query: 1585 TYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQ 1644
Y ++ ++ G R S+ T L++ N + R+L + FL Q
Sbjct: 940 FYTALRKESGTKLVDGTGHRPHYSLRTLCR--ALRFAASNPCGNIQRSLYEGFCLGFLTQ 997
Query: 1645 ----DVPLFQGIISD-LFPGVV-------LPKPDYEVFLKVLNDNIKKMKLQPV---PWF 1689
P+ Q +I + PG V +P+P ++V I +P +
Sbjct: 998 LDRASHPIVQKLICQHIVPGNVKSLLKQPIPEPKGGRLIQVEGYWIAVGDKEPTIDETYI 1057
Query: 1690 IGKIIQIYEMMLVR------HGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEY 1743
+ +++ +VR + +I G+ GKTS + LAAA G+ H
Sbjct: 1058 LTSSVKLNLRDIVRVVSAGTYPVLIQGETSVGKTSLIQWLAAATGN-HCV---------- 1106
Query: 1744 KIINPKAITMGQLYGCFDQVSH---EWMDGVLANAFREQASSLSDDRKWIIFD----GPV 1796
+I N + + + GC+ S + +GVL +A R+ WII D P
Sbjct: 1107 RINNHEHTDIQEYIGCYTSDSSGKLVFKEGVLIDAMRK--------GYWIILDELNLAPT 1158
Query: 1797 DAIWIENMNTVLDDNKKLCLM-SGEIIQMNSKMSL 1830
D +E +N +LDDN++L + + E+++ + + L
Sbjct: 1159 DV--LEALNRLLDDNRELLVTETQEVVKAHPRFML 1191
Score = 37.4 bits (85), Expect = 0.31
Identities = 103/474 (21%), Positives = 172/474 (36%), Gaps = 93/474 (19%)
Query: 1406 PLTDRCYRTLMGALKLNL---------GGAP---EGPAGTGKTETTKDLAKALAKQCVVF 1453
P D Y L ++KLNL G P +G GKT + LA A CV
Sbjct: 1050 PTIDETY-ILTSSVKLNLRDIVRVVSAGTYPVLIQGETSVGKTSLIQWLAAATGNHCVRI 1108
Query: 1454 NCSDGLDYK---------AMGK--FFKGL----AQAGAWACFDEFNRIEVEVLSVVAQQI 1498
N + D + + GK F +G+ + G W DE N +VL + + +
Sbjct: 1109 NNHEHTDIQEYIGCYTSDSSGKLVFKEGVLIDAMRKGYWIILDELNLAPTDVLEALNRLL 1168
Query: 1499 LSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPG--YAGRAELPDNLKALFRTVAM-M 1555
++ ++ + + + +P +F T NP Y GR L + F +
Sbjct: 1169 DDNRELLVTETQEVV------KAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFDE 1222
Query: 1556 VPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCS-EQLSSQHHYDYGMRAVKSVLTAAG 1614
+P L E L+ L ++ + L S + SS G ++ + A
Sbjct: 1223 LPSSEL--ETILHKRCSLPPSYCSKLVKVMLDLQSYRRSSSVFAGKQGFITLRDLFRWAE 1280
Query: 1615 NLKLKYPEE----------NESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPK 1664
+L P E N+ +LL + + Q+V L + L P + K
Sbjct: 1281 RYRLAEPTEKEYDWLQHLANDGYMLLAGRVRKQEEIDVIQEV-LEKHFKKKLCPQSLFSK 1339
Query: 1665 PDYEVFLKVLNDNIKKMK-----------LQPVPWFIGKIIQIYEMMLVRHGYMIVGDPM 1713
+ L L+ I ++ ++ + +G+ ++ E +L +VGD
Sbjct: 1340 ENVLKLLGKLSTQISTLECNFGHIVWTEGMRRLAMLVGRALEFGEPVL------LVGDTG 1393
Query: 1714 GGKTSAYKVLAAALG------DLHAANQMEEF-----AVEYKIINPKAITMGQLYGCFDQ 1762
GKT+ +V AA H + +F V K + + I +L+
Sbjct: 1394 CGKTTICQVFAALANQKLYSVSCHLHMETSDFLGGLRPVRQKPNDKEEIDTSRLF----- 1448
Query: 1763 VSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCL 1816
EW DG L A +E L D+ D +E +N+VL+ K L L
Sbjct: 1449 ---EWHDGPLVQAMKEDGFFLLDEISL------ADDSVLERLNSVLEVEKSLVL 1493
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 40.4 bits (93), Expect = 0.037
Identities = 38/136 (27%), Positives = 56/136 (41%), Gaps = 15/136 (11%)
Query: 712 VSEVPANTKELVSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDYADLPYQIEDIFDNS 771
V E+ A EL E K S K +Q RD SE LE L ++ED D +
Sbjct: 1113 VRELQAQIAELQEDFESEKASRN----KAEKQKRDLSEELEALKT------ELEDTLDTT 1162
Query: 772 --RNLLLHKRDQAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELS 829
+ L KR+Q +L K E + + +++ R+R EE+ +E+
Sbjct: 1163 AAQQELRTKREQEVAELKKALEE---ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFK 1219
Query: 830 KNLNRAFAEFELINKE 845
NL + E NKE
Sbjct: 1220 ANLEKNKQGLETDNKE 1235
Score = 32.3 bits (72), Expect = 10.0
Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 22/114 (19%)
Query: 741 RRQLRDASERLEFLMDYADLPYQIEDIFDNSRNLLLHKRDQAEMDLIKRCSEFELRLEGY 800
+R L AS++ + +D DL QIE ++A ++IK+ + + +++ Y
Sbjct: 1611 QRALAVASKK-KMEIDLKDLEAQIE------------AANKARDEVIKQLRKLQAQMKDY 1657
Query: 801 HRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAEFELINKEEELLEKEKS 854
RELE R + K + +KL L E E++ +EEL E++
Sbjct: 1658 QRELEEARASRDEIFAQSKESEKKLKSL---------EAEILQLQEELASSERA 1702
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 40.4 bits (93), Expect = 0.037
Identities = 63/326 (19%), Positives = 127/326 (38%), Gaps = 42/326 (12%)
Query: 677 ERAQNLKDHLIQFQVDVNRDTNT--SICNQYSHIADKVSEVPANTKELVSLIEFLKKSSA 734
E + +L L FQ ++ ++ N Q DK+ + + LV +E KS A
Sbjct: 265 ELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRA 324
Query: 735 VTVFKLRRQLRDASERLE------------FLMDYADLPYQIEDI---FDNSRNLLLHKR 779
+ L +L+ LE Y + +ED+ F++ + L +
Sbjct: 325 EELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEI 384
Query: 780 DQAEM-----------------DLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHN- 821
+ ++ D+ + E + Y R L + + + E+K
Sbjct: 385 EDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEIT 444
Query: 822 ---VEKLNELSKNLNRAFAEF--ELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTA 876
++K+ +L L + +F +L ++E EKE +T L + + K ++ YE+L++
Sbjct: 445 VSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKT 504
Query: 877 YEFSIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDK 936
F ++ + + LLN A+E N R +Y K L +++ VK+K +
Sbjct: 505 KPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSY--AKLLGHQNLKQKIKHVVKLKDEN 562
Query: 937 FKQYIPILSISCNPGMKDRHWQQISE 962
+ + + C K + ++ E
Sbjct: 563 SQLKSEVSKLRCQLAKKKQSETKLQE 588
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 40.4 bits (93), Expect = 0.037
Identities = 63/326 (19%), Positives = 127/326 (38%), Gaps = 42/326 (12%)
Query: 677 ERAQNLKDHLIQFQVDVNRDTNT--SICNQYSHIADKVSEVPANTKELVSLIEFLKKSSA 734
E + +L L FQ ++ ++ N Q DK+ + + LV +E KS A
Sbjct: 352 ELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRA 411
Query: 735 VTVFKLRRQLRDASERLE------------FLMDYADLPYQIEDI---FDNSRNLLLHKR 779
+ L +L+ LE Y + +ED+ F++ + L +
Sbjct: 412 EELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEI 471
Query: 780 DQAEM-----------------DLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHN- 821
+ ++ D+ + E + Y R L + + + E+K
Sbjct: 472 EDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEIT 531
Query: 822 ---VEKLNELSKNLNRAFAEF--ELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTA 876
++K+ +L L + +F +L ++E EKE +T L + + K ++ YE+L++
Sbjct: 532 VSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKT 591
Query: 877 YEFSIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDK 936
F ++ + + LLN A+E N R +Y K L +++ VK+K +
Sbjct: 592 KPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSY--AKLLGHQNLKQKIKHVVKLKDEN 649
Query: 937 FKQYIPILSISCNPGMKDRHWQQISE 962
+ + + C K + ++ E
Sbjct: 650 SQLKSEVSKLRCQLAKKKQSETKLQE 675
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 40.4 bits (93), Expect = 0.037
Identities = 63/326 (19%), Positives = 127/326 (38%), Gaps = 42/326 (12%)
Query: 677 ERAQNLKDHLIQFQVDVNRDTNT--SICNQYSHIADKVSEVPANTKELVSLIEFLKKSSA 734
E + +L L FQ ++ ++ N Q DK+ + + LV +E KS A
Sbjct: 336 ELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRA 395
Query: 735 VTVFKLRRQLRDASERLE------------FLMDYADLPYQIEDI---FDNSRNLLLHKR 779
+ L +L+ LE Y + +ED+ F++ + L +
Sbjct: 396 EELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEI 455
Query: 780 DQAEM-----------------DLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHN- 821
+ ++ D+ + E + Y R L + + + E+K
Sbjct: 456 EDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEIT 515
Query: 822 ---VEKLNELSKNLNRAFAEF--ELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTA 876
++K+ +L L + +F +L ++E EKE +T L + + K ++ YE+L++
Sbjct: 516 VSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKT 575
Query: 877 YEFSIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDK 936
F ++ + + LLN A+E N R +Y K L +++ VK+K +
Sbjct: 576 KPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSY--AKLLGHQNLKQKIKHVVKLKDEN 633
Query: 937 FKQYIPILSISCNPGMKDRHWQQISE 962
+ + + C K + ++ E
Sbjct: 634 SQLKSEVSKLRCQLAKKKQSETKLQE 659
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 40.4 bits (93), Expect = 0.037
Identities = 63/326 (19%), Positives = 127/326 (38%), Gaps = 42/326 (12%)
Query: 677 ERAQNLKDHLIQFQVDVNRDTNT--SICNQYSHIADKVSEVPANTKELVSLIEFLKKSSA 734
E + +L L FQ ++ ++ N Q DK+ + + LV +E KS A
Sbjct: 351 ELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRA 410
Query: 735 VTVFKLRRQLRDASERLE------------FLMDYADLPYQIEDI---FDNSRNLLLHKR 779
+ L +L+ LE Y + +ED+ F++ + L +
Sbjct: 411 EELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEI 470
Query: 780 DQAEM-----------------DLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHN- 821
+ ++ D+ + E + Y R L + + + E+K
Sbjct: 471 EDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEIT 530
Query: 822 ---VEKLNELSKNLNRAFAEF--ELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTA 876
++K+ +L L + +F +L ++E EKE +T L + + K ++ YE+L++
Sbjct: 531 VSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKT 590
Query: 877 YEFSIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDK 936
F ++ + + LLN A+E N R +Y K L +++ VK+K +
Sbjct: 591 KPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSY--AKLLGHQNLKQKIKHVVKLKDEN 648
Query: 937 FKQYIPILSISCNPGMKDRHWQQISE 962
+ + + C K + ++ E
Sbjct: 649 SQLKSEVSKLRCQLAKKKQSETKLQE 674
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 40.0 bits (92), Expect = 0.048
Identities = 60/288 (20%), Positives = 111/288 (38%), Gaps = 39/288 (13%)
Query: 622 EQNIAAFLKENHDIDDFVTKI-NAIKKRRNEIA-----SMNITVPLAMFCLDATALNHDL 675
EQ I +N + D + + ++ K NE+ M+ + T L ++
Sbjct: 2566 EQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREM 2625
Query: 676 CERAQNLKDHLIQFQVDVNRDTNTS--ICNQYSHIADKVSEVPANTKELVSLIEFLKKSS 733
E AQ + + + NR + + D++ E+ EL ++ + K
Sbjct: 2626 HEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQ 2685
Query: 734 AVTVFKLRRQ-------LRDASERLEFLMDYADLPYQIEDIFDNSRNLLLHKRD-----Q 781
K+R + L +A ++ + L+ + Y++E R L K + +
Sbjct: 2686 VEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVE--IQTYREKLTSKEECLSSQK 2743
Query: 782 AEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKH----NVEKLNELSKNLNRAFA 837
E+DL+K E EL + K EE+K N++ +N+L K RA
Sbjct: 2744 LEIDLLKSSKE----------ELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQG 2793
Query: 838 EFELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEE 885
+ +L+ K + LE+EK +LQ L ++ T K +E
Sbjct: 2794 KMKLLIKSCKQLEEEKE---ILQKELSQLQAAQEKQKTGTVMDTKVDE 2838
Score = 36.6 bits (83), Expect = 0.53
Identities = 33/111 (29%), Positives = 48/111 (43%), Gaps = 25/111 (22%)
Query: 768 FDNSRNL-LLHKRDQAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLN 826
FDNS + LL + +L + +E ELRL+G+ + EMK V K
Sbjct: 271 FDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEK--------------EMKGQVNKFQ 316
Query: 827 ELSKNLNRAFAEFELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAY 877
EL L +A + EL+EKEK +++ Y+Q ST Y
Sbjct: 317 ELQLQLEKA---------KVELIEKEKVLNKCRDELVRTTAQYDQA-STKY 357
Score = 34.3 bits (77), Expect = 2.6
Identities = 33/115 (28%), Positives = 48/115 (41%), Gaps = 13/115 (11%)
Query: 2914 KLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISG 2973
+L AQ Q+L K EL+L RLQ + + K ++L+ +E +L+ EK+++
Sbjct: 282 QLKAQNQELRNKINELEL---RLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNK 338
Query: 2974 LGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAEC 3028
E R T Q +YT L L T D Q QN A C
Sbjct: 339 CRDELVRTTAQYDQASTKYTALE----------QKLKKLTEDLSCQRQNAESARC 383
Score = 33.1 bits (74), Expect = 5.8
Identities = 70/331 (21%), Positives = 131/331 (39%), Gaps = 32/331 (9%)
Query: 618 DNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNITVPLAMFCLDATALNHDLCE 677
DN +Q + L+E +++ + RN++ T+ LD L+ + E
Sbjct: 1938 DNENKQKVIVCLEE---------ELSVVTSERNQLRGELDTMSKKTTALDQ--LSEKMKE 1986
Query: 678 RAQNLKDHLIQFQ--VDVNRDTNTSICNQYSHIADKVSEVPANTKELVSLIEFLKKSS-- 733
+ Q L+ H + + V ++ VSE+ + L ++ L+K S
Sbjct: 1987 KTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQA 2046
Query: 734 -AVTVFKLRRQLRDASERLEFLMDYADLPYQIEDIFDNSRNLLLHKRDQAEMDLIKRCSE 792
++T +L Q+ ++ E L+ ++ ++ S L+ E L+++ E
Sbjct: 2047 LSLTKCELENQIAQLNKEKELLVKESE---SLQARLSESDYEKLNVSKALEAALVEK-GE 2102
Query: 793 FELRLEGYHRELESFRK-----REVMTTEEMK--HNVEKLNELSKNLNRAFAEFELINKE 845
F LRL E+ R+ R + +E K H EKL E + + + E N E
Sbjct: 2103 FALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVE--NLE 2160
Query: 846 EELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQ--IAEEI 903
EL E++ ++ +K E L T E +S + L L +E+ + ++I
Sbjct: 2161 RELQMSEENQELVILDAENSKAEVETL-KTQIEEMARSLKVFELDLVTLRSEKENLTKQI 2219
Query: 904 GNMWRTTYKLIKTLSDVPAPRRLAENVKIKI 934
+L K LS + E +I+I
Sbjct: 2220 QEKQGQLSELDKLLSSFKSLLEEKEQAEIQI 2250
Score = 32.3 bits (72), Expect = 10.0
Identities = 31/150 (20%), Positives = 68/150 (45%), Gaps = 18/150 (12%)
Query: 2620 EVVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRY 2679
E+ S+C+ +++S++KL K+ + EL + LL+S+RQE+ +R +Y
Sbjct: 1551 ELESLCEVYRQSLEKLE----EKMESQGIMKNKEIQEL----EQLLSSERQELDCLRKQY 1602
Query: 2680 LTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKL----LV 2735
L+ ++ + V + ++ +L ++T ++ +++E + G L L+
Sbjct: 1603 LSENEQWQQKLTSVTL------EMESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLL 1656
Query: 2736 QADEKEANVAAAIAQGIKNECEGDLAEAMP 2765
D ++A + I E + E P
Sbjct: 1657 GIDTEDAIQGRNESCDISKEHTSETTERTP 1686
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 151,193,579
Number of Sequences: 37866
Number of extensions: 6804246
Number of successful extensions: 21813
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 154
Number of HSP's that attempted gapping in prelim test: 20145
Number of HSP's gapped (non-prelim): 1518
length of query: 4116
length of database: 18,247,518
effective HSP length: 123
effective length of query: 3993
effective length of database: 13,590,000
effective search space: 54264870000
effective search space used: 54264870000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.