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Search of human proteins with 24308029
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
(2069 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens] 4143 0.0
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens] 4064 0.0
gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens] 2480 0.0
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens] 2437 0.0
gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens] 2401 0.0
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] 2187 0.0
gi|157426887 dedicator of cytokinesis 6 [Homo sapiens] 791 0.0
gi|54112429 dedicator of cytokinesis 7 [Homo sapiens] 565 e-160
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens] 515 e-145
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens] 85 6e-16
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens] 69 5e-11
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens] 69 6e-11
gi|31377468 dedicator of cytokinesis 2 [Homo sapiens] 65 5e-10
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens] 65 7e-10
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap... 46 4e-04
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi... 46 4e-04
gi|55741447 pleckstrin homology domain containing, family H (wit... 45 0.001
gi|217416392 pleckstrin homology domain containing, family H (wi... 44 0.001
gi|187608516 centaurin, beta 2 [Homo sapiens] 42 0.005
gi|24432056 hypothetical protein LOC144717 [Homo sapiens] 42 0.006
gi|5031805 insulin receptor substrate 1 [Homo sapiens] 41 0.014
gi|238908495 similar to pleckstrin homology domain protein (5V32... 40 0.018
gi|219689123 pleckstrin homology domain containing, family A mem... 40 0.018
gi|19923493 pleckstrin homology domain containing, family A memb... 40 0.018
gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [H... 40 0.031
gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [H... 40 0.031
gi|7661880 centaurin beta1 [Homo sapiens] 39 0.040
gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa... 39 0.053
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 39 0.069
gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens] 37 0.15
>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
Length = 2069
Score = 4143 bits (10745), Expect = 0.0
Identities = 2069/2069 (100%), Positives = 2069/2069 (100%)
Query: 1 MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60
MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ
Sbjct: 1 MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60
Query: 61 KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120
KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD
Sbjct: 61 KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120
Query: 121 WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180
WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW
Sbjct: 121 WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180
Query: 181 LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240
LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ
Sbjct: 181 LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240
Query: 241 NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300
NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD
Sbjct: 241 NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300
Query: 301 EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360
EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF
Sbjct: 301 EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360
Query: 361 EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420
EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL
Sbjct: 361 EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420
Query: 421 NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480
NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE
Sbjct: 421 NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480
Query: 481 KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540
KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL
Sbjct: 481 KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540
Query: 541 DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600
DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV
Sbjct: 541 DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600
Query: 601 NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660
NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK
Sbjct: 601 NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660
Query: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720
ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT
Sbjct: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720
Query: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780
QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN
Sbjct: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780
Query: 781 LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840
LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES
Sbjct: 781 LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840
Query: 841 GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900
GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA
Sbjct: 841 GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900
Query: 901 QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960
QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS
Sbjct: 901 QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960
Query: 961 WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020
WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK
Sbjct: 961 WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020
Query: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080
NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP
Sbjct: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080
Query: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140
LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL
Sbjct: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140
Query: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200
KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES
Sbjct: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200
Query: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLISTD 1260
LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLISTD
Sbjct: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLISTD 1260
Query: 1261 SGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALF 1320
SGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALF
Sbjct: 1261 SGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALF 1320
Query: 1321 TYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFNHSYG 1380
TYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFNHSYG
Sbjct: 1321 TYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFNHSYG 1380
Query: 1381 HSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFL 1440
HSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFL
Sbjct: 1381 HSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFL 1440
Query: 1441 QKHQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQL 1500
QKHQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQL
Sbjct: 1441 QKHQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQL 1500
Query: 1501 LYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLI 1560
LYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLI
Sbjct: 1501 LYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLI 1560
Query: 1561 KHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDS 1620
KHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDS
Sbjct: 1561 KHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDS 1620
Query: 1621 MARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQ 1680
MARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQ
Sbjct: 1621 MARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQ 1680
Query: 1681 GCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKL 1740
GCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKL
Sbjct: 1681 GCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKL 1740
Query: 1741 IIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSE 1800
IIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSE
Sbjct: 1741 IIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSE 1800
Query: 1801 TDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLD 1860
TDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLD
Sbjct: 1801 TDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLD 1860
Query: 1861 SKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRT 1920
SKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRT
Sbjct: 1861 SKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRT 1920
Query: 1921 ILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKL 1980
ILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKL
Sbjct: 1921 ILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKL 1980
Query: 1981 QGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKE 2040
QGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKE
Sbjct: 1981 QGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKE 2040
Query: 2041 DQLEYQEEMKANYREMAKELSEIMHEQLG 2069
DQLEYQEEMKANYREMAKELSEIMHEQLG
Sbjct: 2041 DQLEYQEEMKANYREMAKELSEIMHEQLG 2069
>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
Length = 2068
Score = 4064 bits (10540), Expect = 0.0
Identities = 2026/2026 (100%), Positives = 2026/2026 (100%)
Query: 44 AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 103
AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE
Sbjct: 43 AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 102
Query: 104 EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 163
EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE
Sbjct: 103 EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162
Query: 164 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 223
DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS
Sbjct: 163 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 222
Query: 224 KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283
KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN
Sbjct: 223 KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 282
Query: 284 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 343
FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP
Sbjct: 283 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 342
Query: 344 DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 403
DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL
Sbjct: 343 DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 402
Query: 404 FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 463
FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI
Sbjct: 403 FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 462
Query: 464 FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 523
FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM
Sbjct: 463 FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 522
Query: 524 PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 583
PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG
Sbjct: 523 PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 582
Query: 584 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643
NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL
Sbjct: 583 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 642
Query: 644 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703
YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH
Sbjct: 643 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702
Query: 704 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763
HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL
Sbjct: 703 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 762
Query: 764 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823
KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT
Sbjct: 763 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 822
Query: 824 QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 883
QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT
Sbjct: 823 QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 882
Query: 884 QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 943
QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI
Sbjct: 883 QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 942
Query: 944 LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1003
LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM
Sbjct: 943 LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1002
Query: 1004 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1063
LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE
Sbjct: 1003 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1062
Query: 1064 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1123
YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG
Sbjct: 1063 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1122
Query: 1124 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1183
TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR
Sbjct: 1123 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1182
Query: 1184 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPN 1243
DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPN
Sbjct: 1183 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPN 1242
Query: 1244 INSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSL 1303
INSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSL
Sbjct: 1243 INSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSL 1302
Query: 1304 LMCFLYILKSMSDDALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARL 1363
LMCFLYILKSMSDDALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARL
Sbjct: 1303 LMCFLYILKSMSDDALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARL 1362
Query: 1364 QQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADH 1423
QQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADH
Sbjct: 1363 QQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADH 1422
Query: 1424 GHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEIL 1483
GHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEIL
Sbjct: 1423 GHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEIL 1482
Query: 1484 KCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRF 1543
KCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRF
Sbjct: 1483 KCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRF 1542
Query: 1544 QQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSL 1603
QQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSL
Sbjct: 1543 QQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSL 1602
Query: 1604 AKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLP 1663
AKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLP
Sbjct: 1603 AKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLP 1662
Query: 1664 HSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCAD 1723
HSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCAD
Sbjct: 1663 HSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCAD 1722
Query: 1724 GLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYF 1783
GLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYF
Sbjct: 1723 GLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYF 1782
Query: 1784 RVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSE 1843
RVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSE
Sbjct: 1783 RVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSE 1842
Query: 1844 NVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFT 1903
NVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFT
Sbjct: 1843 NVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFT 1902
Query: 1904 QTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELR 1963
QTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELR
Sbjct: 1903 QTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELR 1962
Query: 1964 QLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQF 2023
QLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQF
Sbjct: 1963 QLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQF 2022
Query: 2024 VEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQLG 2069
VEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQLG
Sbjct: 2023 VEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQLG 2068
>gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]
Length = 1254
Score = 2480 bits (6427), Expect = 0.0
Identities = 1233/1235 (99%), Positives = 1234/1235 (99%)
Query: 1 MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60
MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ
Sbjct: 1 MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60
Query: 61 KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120
KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD
Sbjct: 61 KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120
Query: 121 WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180
WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW
Sbjct: 121 WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180
Query: 181 LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240
LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ
Sbjct: 181 LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240
Query: 241 NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300
NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD
Sbjct: 241 NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300
Query: 301 EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360
EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF
Sbjct: 301 EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360
Query: 361 EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420
EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL
Sbjct: 361 EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420
Query: 421 NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480
NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE
Sbjct: 421 NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480
Query: 481 KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540
KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL
Sbjct: 481 KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540
Query: 541 DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600
DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV
Sbjct: 541 DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600
Query: 601 NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660
NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK
Sbjct: 601 NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660
Query: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720
ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT
Sbjct: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720
Query: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780
QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN
Sbjct: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780
Query: 781 LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840
LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES
Sbjct: 781 LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840
Query: 841 GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900
GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA
Sbjct: 841 GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900
Query: 901 QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960
QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS
Sbjct: 901 QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960
Query: 961 WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020
WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK
Sbjct: 961 WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020
Query: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080
NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP
Sbjct: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080
Query: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140
LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL
Sbjct: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140
Query: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200
KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES
Sbjct: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200
Query: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIAS 1235
LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGI +
Sbjct: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGN 1235
>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
Length = 2073
Score = 2437 bits (6317), Expect = 0.0
Identities = 1237/2099 (58%), Positives = 1569/2099 (74%), Gaps = 106/2099 (5%)
Query: 11 AETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQKKTQILNDCL 70
AE RKFT+ LSKPGTAAELRQSVSE VRGSV+L K K++EPLDYENVI Q+KTQI +D L
Sbjct: 2 AEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPL 61
Query: 71 REMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWHLVNYKYED 130
R++L+FP +D +++ RQ R + STVP AE+ AQSLFV ECIKTY++DWH+VNYKYED
Sbjct: 62 RDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYED 121
Query: 131 YSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAI 190
+SG+FR LP K ++ +K+P HV+E+DE+ +KDED++SL SQKGG+ K GWL+K N+NS I
Sbjct: 122 FSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTI 181
Query: 191 SVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFE 250
+VTM+ FKRR+F+L QL DGSY LN YKDEK SKE KG I+LD+C+ VVQ K+RR AFE
Sbjct: 182 TVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFE 241
Query: 251 LKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNG-DSHEDDE---QSKLE 306
LKM DK S+ LAA++E EMEEW+ L KI+Q+N ++ +QEK+ ++ +DDE Q K E
Sbjct: 242 LKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAE 301
Query: 307 GSGSGLD-SYLPELAKSAREAEIKLK---SESRVKLFYLDPDAQKLDFSSAEPEVKSFEE 362
+ L+ S PEL K RE E K + R LF D + Q+LDFS EP++K FEE
Sbjct: 302 NIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEE 361
Query: 363 KFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNH 422
K KR LV C+DL+FN+ + +N +GP TNVEPFF+ L+LFD+K N KISADFHVDLN
Sbjct: 362 KCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNP 421
Query: 423 FSVRQMLATTSPALMNGSGQSPSVLKGILH---EAAMQYPKQGIFSVTCPHPDIFLVARI 479
SVR+ML +S L + S + +H E+ ++Y +QGIFSVT PHP+IFLVARI
Sbjct: 422 PSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARI 481
Query: 480 EKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGN 539
EKVLQG+ITHCAEPY+K+SD K AQKV + AKQ C RLGQYRMPFAWAAR +FKD G+
Sbjct: 482 EKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGS 541
Query: 540 LDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNY 599
LD + RFS +Y+QDS+KLS++D+LKLL++++KPEK KL +I G L+IT++ V D N
Sbjct: 542 LDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEK-TKLQIIPGQLNITVECVPVDLSNC 600
Query: 600 VNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFA 659
+ SSY+P K FE + IT EVEEFVP + K+ P+TIY NHLYVYP LKYDSQK+FA
Sbjct: 601 ITSSYVPLKPFEKNCQN-ITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFA 659
Query: 660 KARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELP 719
KARNIA+C+EF+DSDE D+ LKCIYG+P G VFT +A+A V HH+QNPEFYDEIKIELP
Sbjct: 660 KARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELP 719
Query: 720 TQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSA 779
LH+KHHLL TF+HVSC+ ++KG+TKK+D VET VG++W+PLLKDGR++T EQ +PVSA
Sbjct: 720 IHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSA 779
Query: 780 NLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTE 839
NLP GYL + R +IKWVDG KPLLKI +HL ST+YTQD H+H FF +CQ +
Sbjct: 780 NLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQ 839
Query: 840 SGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEE-VAVNVTRVIIHV 898
SG++ + EL+KYLK LHAME VMI FLP IL QLFRVLT T E+ V +N T V++H+
Sbjct: 840 SGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHI 899
Query: 899 VAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLK 958
V++CHEEGL+S+LRS++KY+++ E A + + +HE L +M ILK SADFL+ NKLLK
Sbjct: 900 VSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLK 959
Query: 959 YSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEA 1018
YSWFFF+++ KSMA +L+E +K+KL R QRFP +YHH + +++ ++PH+T ++ + P+
Sbjct: 960 YSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDE 1019
Query: 1019 SKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHY 1078
S+N N+SLA F+KRC T MDRGF+F IN+YIS F+P DPK L EYKFEFL+ +CNHEHY
Sbjct: 1020 SRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHY 1079
Query: 1079 IPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAIS 1138
IPLNLPM F K ++QR QD L+YSL+DE+C++HFLVGLLLRE ALQ+ E+R AIS
Sbjct: 1080 IPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAIS 1139
Query: 1139 VLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDV----SPFPVNAGM 1194
V+KNLLIKH+FD RY ++ QA+IA LYLP GLL+EN+QR+ RD + P +A
Sbjct: 1140 VIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASR 1199
Query: 1195 TVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRG 1254
PA G++S S N + ++ DSRG
Sbjct: 1200 DEFPCGFTSPANR--------------------GSLSTDKDTAYGSFQNGHGIKREDSRG 1239
Query: 1255 SLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSM 1314
SLI + P++ + N+ +QSST +SV + ++LDQ EI+SLLMC+LYI+K +
Sbjct: 1240 SLI-PEGATGFPDQGNTGENT----RQSST-RSSVSQYNRLDQYEIRSLLMCYLYIVKMI 1293
Query: 1315 SDDALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIA-------------------- 1354
S+D L TYWNK S EL++ + EVCL F+YMGKR IA
Sbjct: 1294 SEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTM 1353
Query: 1355 -----RTGMMHARLQQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLS 1409
R+G+M ARLQ L SL++S T NHS ++AD+ HQ+LLE N ATEV LT LDT+S
Sbjct: 1354 PALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFHQALLEGNTATEVSLTVLDTIS 1413
Query: 1410 LFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYE 1469
FT FK QLL + GHNPLMKKVFD++L FL+ QSE +LK+VF +LR+ I KFPS F++
Sbjct: 1414 FFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFK 1473
Query: 1470 GRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVS 1529
GR +MCAA CYE+LKCC SK+SS R EAS LLY LMRNNF+YT +K+F+RTHLQ+II+VS
Sbjct: 1474 GRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVS 1533
Query: 1530 QLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEH 1589
QLIADV GG+RFQ+SL IINN ANSDR +K T+F ++VKDLTKRIRTVLMATAQMKEH
Sbjct: 1534 QLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMKEH 1593
Query: 1590 ENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYL 1649
E DPEML+DLQYSLAKSYASTPELRKTWLDSMA+IHVKNGD SEAAMCYVHV ALVAE+L
Sbjct: 1594 EKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFL 1653
Query: 1650 TRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHF 1709
RK+ +F GC+AF+ ITPNIDEE +M ED GM DVH+
Sbjct: 1654 HRKK-----------------------LFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHY 1690
Query: 1710 NEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVT 1769
+E+VL+ELLEQC DGLWKAERYE+I++I KLI+PIYEKRR+FE+L +Y TLH AY+K+
Sbjct: 1691 SEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKIL 1750
Query: 1770 EVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEIS 1829
EVMH+ +RLLGT+FRVAF+GQ+ FFE+EDGKEYIYKEPKLT LSEIS
Sbjct: 1751 EVMHTKKRLLGTFFRVAFYGQS--------------FFEEEDGKEYIYKEPKLTGLSEIS 1796
Query: 1830 QRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFER 1889
RL+KLY +KFG+ENVK+IQDS KVN K+LD KYA+IQVT+V P+FD+KEL ERKTEFER
Sbjct: 1797 LRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFER 1856
Query: 1890 SHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIE 1949
+HNI RF+FE P+T +GK+QG +EEQCKRRTILT + FPYVKKRIP+ + +L PI+
Sbjct: 1857 NHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPID 1916
Query: 1950 VAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYP 2009
VA DE+ K AEL++LCSS +VDMI+LQLKLQG VSVQVNAGPLAYARAFL+D+ +YP
Sbjct: 1917 VATDEIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYP 1976
Query: 2010 DNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQL 2068
KV LK++FR+F++AC AL +NERLIKEDQ+EY E +K+N+R+M KELS+I+HEQ+
Sbjct: 1977 PKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQI 2035
>gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]
Length = 1253
Score = 2401 bits (6222), Expect = 0.0
Identities = 1190/1192 (99%), Positives = 1191/1192 (99%)
Query: 44 AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 103
AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE
Sbjct: 43 AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 102
Query: 104 EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 163
EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE
Sbjct: 103 EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162
Query: 164 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 223
DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS
Sbjct: 163 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 222
Query: 224 KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283
KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN
Sbjct: 223 KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 282
Query: 284 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 343
FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP
Sbjct: 283 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 342
Query: 344 DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 403
DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL
Sbjct: 343 DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 402
Query: 404 FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 463
FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI
Sbjct: 403 FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 462
Query: 464 FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 523
FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM
Sbjct: 463 FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 522
Query: 524 PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 583
PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG
Sbjct: 523 PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 582
Query: 584 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643
NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL
Sbjct: 583 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 642
Query: 644 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703
YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH
Sbjct: 643 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702
Query: 704 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763
HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL
Sbjct: 703 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 762
Query: 764 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823
KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT
Sbjct: 763 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 822
Query: 824 QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 883
QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT
Sbjct: 823 QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 882
Query: 884 QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 943
QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI
Sbjct: 883 QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 942
Query: 944 LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1003
LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM
Sbjct: 943 LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1002
Query: 1004 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1063
LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE
Sbjct: 1003 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1062
Query: 1064 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1123
YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG
Sbjct: 1063 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1122
Query: 1124 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1183
TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR
Sbjct: 1123 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1182
Query: 1184 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIAS 1235
DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGI +
Sbjct: 1183 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGN 1234
>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
Length = 2186
Score = 2187 bits (5668), Expect = 0.0
Identities = 1147/2177 (52%), Positives = 1532/2177 (70%), Gaps = 146/2177 (6%)
Query: 9 ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLA------KPKLIEPLDYENVIVQKK 62
A TR+FTR+L +PG AAELR S + +V KP+L+EPLDYE VI + +
Sbjct: 2 AGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEELE 61
Query: 63 TQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWH 122
ND L+++L FP DDF A + R + STVP AE +A++L V E K Y+S WH
Sbjct: 62 KTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQWH 121
Query: 123 LVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVD-EEVDKDEDAASLGSQKGG------- 174
+VNYKYE YSG+ RQLP K +KLP H +E+D E+ DKDED S S KGG
Sbjct: 122 VVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGTG 181
Query: 175 ITKHGWLYKGNMNSAIS--VTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFL 232
+ K GWLYKGN NS ++ VT+RSFK+R+F L QL D SY +NFYKDEKISKEPKG IFL
Sbjct: 182 VFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFL 241
Query: 233 DSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKR 292
DSC GVVQNN++R++AFELKM D + ++LAA++E +M+EWI LN+ILQ++ E +Q +R
Sbjct: 242 DSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRR 301
Query: 293 NG-------DSHEDDEQSKL--EGSGSGLDSYLPELAKSAREAEIKLKSE---SRVKLFY 340
+ DS ++ + E + S ++ + AK E E +K+ R+ LF
Sbjct: 302 STELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLFS 361
Query: 341 LDPDA-----QKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVE 395
LDPD QK D E +K FEEK KRI++ C L+ NLQ CV ENE P TN+E
Sbjct: 362 LDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIE 421
Query: 396 PFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGS--------GQSPSVL 447
PFFV+++L+D++ +RKISADFHVDLNH +VRQML S AL NG+ + P +
Sbjct: 422 PFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHI- 480
Query: 448 KGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKV 507
KG L E +++PKQ +FSV+ PH +I LVA+IEKVL G+I AEPY+K+ DS+K AQK+
Sbjct: 481 KG-LPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKI 539
Query: 508 LKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLA 567
LK+ +Q C +LG+YRMPFAWA R++FKD GN+D+++RFS ++RQ+S+K+S +D++KL++
Sbjct: 540 LKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVS 599
Query: 568 DFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVP 627
D+R+ ++++K+ I G+LDI +DNV + PN V SS+IP K F ++T T EVEEFV
Sbjct: 600 DYRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVY 659
Query: 628 CIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGR 687
K+ +PY +Y N +Y+YPK+LKYDSQK F KARNI +CIEFK+SDEE ++PLKCIYG+
Sbjct: 660 DSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGK 719
Query: 688 PGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKK 747
PGGP+FT +A+ AVLHH QNP+F DE+KIELPTQLHEKHH+L +F+HV+CD ++K + KK
Sbjct: 720 PGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKK 779
Query: 748 RDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGG 807
++ +ET VGY+WLPL+K ++ + E +IP++ +LP YL +Q+ G+H G +IKWVDGG
Sbjct: 780 KEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGG 839
Query: 808 KPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG-AQALGNELVKYLKSLHAMEG-HVMI 865
KPL K+ST +VSTV TQD H++ FFQ CQK E +Q+ + ++ K+L +E H ++
Sbjct: 840 KPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIM 899
Query: 866 AFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYV 925
+FLP ILNQLF+VL + ++E+ VTRV+ +VA+CHEE L+ ++SY+K+ +K
Sbjct: 900 SFLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTR--- 956
Query: 926 ASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLR 985
A + +TVHEEL K++T +LK S D T +LK+SWFFF +++KSMAQHLI+ +K++L R
Sbjct: 957 ACKERTVHEELAKNVTGLLK-SNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPR 1015
Query: 986 NQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQ 1045
QRFP SY + ++ +V +L H+ K++D E ++ ANHS+A F+KRCFTFMDRG+VFK
Sbjct: 1016 PQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKM 1075
Query: 1046 INNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLP-----MPFGKGRIQRYQDLQL 1100
+NNYIS F+ GD KTL +YKF+FL+ VC HEH+IPL LP +P + Q+L
Sbjct: 1076 VNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHA 1135
Query: 1101 ----DYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLKNLLIKHSFDDRYASR 1156
+YS+T+EFCR HFL+G+LLREVG ALQE ++VR +A++VLKNL+ KHSFDDRY
Sbjct: 1136 SDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREP 1195
Query: 1157 SHQARIATLYLPLFGLLIENVQRINVRDVSPFPVN-AGMTVKDESLALPAVNPLVTPQKG 1215
QA+IA+LY+PL+G+L++N+ RI ++D+ PF VN + +D+ +
Sbjct: 1196 RKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHA 1255
Query: 1216 STLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLISTDSGNSLPERNSEKSNS 1275
+++D S KD+L +I+ S+ I++V +ADSR SL S DS S E++SEK+++
Sbjct: 1256 NSVDTSFSKDVLNSIAAF------SSIAISTVNHADSRASLASLDSNPSTNEKSSEKTDN 1309
Query: 1276 LDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALFTYWNKASTSELMDFF 1335
+K + +L S +R DKLDQ+E +SLLMCFL+I+K++S + L YW +A + E+ DFF
Sbjct: 1310 CEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFF 1369
Query: 1336 TISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFN----------------HSY 1379
+I +VCL F+Y+GKR I R + A + + S N+ T HS
Sbjct: 1370 SILDVCLQNFRYLGKRNIIR--KIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHST 1427
Query: 1380 GHSDADVLHQS----------------LLE----------------------ANIATEVC 1401
+ H+S LL+ ANIATEVC
Sbjct: 1428 SSHEGHKQHRSQTLPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEVC 1487
Query: 1402 LTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIY 1461
LT LD LSLFT + QL N LMK+VFD Y+ F Q +QS TALK+VF +LR +
Sbjct: 1488 LTILDLLSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVC 1547
Query: 1462 KFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTH 1521
KFPS F++G AD+C + CYE+LKCCN + S +TEAS LLYF MR NF++ +KS VR+H
Sbjct: 1548 KFPSAFFQGPADLCGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSH 1607
Query: 1522 LQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLM 1581
LQ+I +VSQLIAD GIGG+RFQ SL+I NN AN D+ +K+++F ++VKDLTKRIRTVLM
Sbjct: 1608 LQLIKAVSQLIAD-AGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLM 1666
Query: 1582 ATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHV 1641
ATAQMKEHE DPEMLVDLQYSLA SYASTPELR+TWL+SMA+IH +NGDLSEAAMCY+H+
Sbjct: 1667 ATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHI 1726
Query: 1642 TALVAEYLTRKEAVQWE----PPLLPH------SHSACLRRSRGGVFRQGCTAFRVITPN 1691
AL+AEYL RK + E LL S+S S G +F G AF ITPN
Sbjct: 1727 AALIAEYLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPN 1786
Query: 1692 IDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDF 1751
I EE +M ED GMQD +NE++L+E L C + LWK+ERYELIAD+ K II ++EK+RDF
Sbjct: 1787 IKEEGAMKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDF 1846
Query: 1752 ERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDED 1811
++L+ LY +HR+Y KV EV++S +RL G Y+RVAF+GQ GFFE+E+
Sbjct: 1847 KKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQ--------------GFFEEEE 1892
Query: 1812 GKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHV 1871
GKEYIYKEPKLT LSEISQRLLKLY+DKFG++NVK+IQDS KVNPKDLD KYAYIQVT+V
Sbjct: 1893 GKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYV 1952
Query: 1872 IPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYV 1931
PFF+EKE+++RKT+FE HNI RF+FE PFT +GK+ GGV EQCKRRTILT H FPYV
Sbjct: 1953 TPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTILTTSHLFPYV 2012
Query: 1932 KKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAG 1991
KKRI V+ Q T+LNPIEVAIDEMSKKV+EL QLC+ EVDMI+LQLKLQGSVSV+VNAG
Sbjct: 2013 KKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVNAG 2072
Query: 1992 PLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKA 2051
P+AYARAFL++TN K+YPDN+VKLLKE+FRQF +ACGQAL VNERLIKEDQLEYQEE+++
Sbjct: 2073 PMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRS 2132
Query: 2052 NYREMAKELSEIMHEQL 2068
+Y++M ELS +M+EQ+
Sbjct: 2133 HYKDMLSELSTVMNEQI 2149
>gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]
Length = 2047
Score = 791 bits (2043), Expect = 0.0
Identities = 599/1997 (29%), Positives = 927/1997 (46%), Gaps = 354/1997 (17%)
Query: 285 EAAMQEKRNGDSHEDDEQSKLEGSGSGL-----DSYLPELAKSAREAEIKLKSES----- 334
E + +R S ED +S S L DS LP L + A ++ ++E+
Sbjct: 167 EDSNDSRRGSGSPEDTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQH 226
Query: 335 ---RVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPT 391
+ Y PD + + PE E FG+RILVKC L F ++
Sbjct: 227 RPPALLTLYPAPDEDEAVERCSRPEPP--REHFGQRILVKCLSLKFEIE----------- 273
Query: 392 TNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGIL 451
+EP F L+L+D++ +KIS +F+ DLN S++ +L
Sbjct: 274 --IEPIFGILALYDVREKKKISENFYFDLNSDSMKGLLRAHGT----------------- 314
Query: 452 HEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPYM--KSSDSSKVAQKVL 508
H A + IFSVT P PDIFLV ++EKVLQ G I+ C EPYM K D++K +K+
Sbjct: 315 HPAISTLARSAIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMVLKEVDTAKNKEKLE 374
Query: 509 K---NAKQACQRLGQYRMPFAWAARTLFK--DASGNLDKNA------------------- 544
K A+Q C RLG+YRMPFAW A L ++G LD+++
Sbjct: 375 KLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSAGQLDRDSDSEGERRPAWTDRRRRGPQ 434
Query: 545 ----------RFSAI----------YRQDSNKLSNDDMLKLLADFRKPEKMAK-LPVILG 583
FS ++Q++ +LS++D+ K LAD R+P + + L +
Sbjct: 435 DRASSGDDACSFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTA 494
Query: 584 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643
L I I + ++ + K + P T E+ EF P + P+T Y N L
Sbjct: 495 QLKIDISPAPENPHFCLSPELLHIKPYPDPRGRP-TKEILEF-PAREVYA-PHTSYRNLL 551
Query: 644 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703
YVYP L + S++ RN+A+ +++ + E+ SQ L I+G+ FTR AF V++
Sbjct: 552 YVYPHSLNFSSRQG--SVRNLAVRVQYM-TGEDPSQALPVIFGKSSCSEFTREAFTPVVY 608
Query: 704 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763
H+++PEFY+E K+ LP + E HHLL TF+HVSC + +ET VG++W+PLL
Sbjct: 609 HNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSC------QPRPGTALETPVGFTWIPLL 662
Query: 764 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823
+ GR+ T +PVS + P + P ++WVDG K + + VS+V+
Sbjct: 663 QHGRLRTGPFCLPVSVDQPPPSYSVLTPDVAL---PGMRWVDGHKGVFSVELTAVSSVHP 719
Query: 824 QDQHLHNFFQYCQKTESGA---------QALGN---ELVKYLKSLHAMEGHVMIAFLPTI 871
QD +L FF E GA + GN EL L +L ++AF +
Sbjct: 720 QDPYLDKFFTLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHV 779
Query: 872 LNQLFRVLTR-ATQEEVAVNVTR----VIIHVVAQCHE--------EGLESHLRSYVKYA 918
L++L R++ R VN+ R + HVV+ H G L +YV YA
Sbjct: 780 LDKLVRLVIRPPIISGQIVNLGRGAFEAMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYA 839
Query: 919 YK----------AEPYVASEYKTVHEELTKSMTTILKPSADFLTSN-------------- 954
++ P V + T+ + + L S +SN
Sbjct: 840 FRLPGTEPSLPDGAPPVTVQAATLARGSGRPASLYLARSKSISSSNPDLAVAPGSVDDEV 899
Query: 955 --------------------------KLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQR 988
+L+++WFFF +++KSMA HL+ ++ R R
Sbjct: 900 SRILASKLLHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLR 959
Query: 989 FPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINN 1048
FP + + +V + + + + E +++ N SLA F+ + +DRGFVF +
Sbjct: 960 FPGRFLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRA 1019
Query: 1049 YISCFA-----PGDPKTLFEYKFEFLRVVCNHEHYIPLNLP-------------MPFGKG 1090
+ A +P L + EF R++C+HEHY+ LNLP +
Sbjct: 1020 HYKQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTS 1079
Query: 1091 RIQRYQDLQLD------YSLTDEFCRNHFLVGLLLREVGTALQEFREVRLI----AISVL 1140
+ + D + L+ F + HFL GLLL E+ AL+ E + AIS +
Sbjct: 1080 QSSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAV 1139
Query: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200
+LL H D RYA + +AR+A LYLPL + + + R++ F G + S
Sbjct: 1140 HSLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLH-----DFAEGPGQRSRLAS 1194
Query: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLISTD 1260
+ D D+ G I+ + P R + S+G ++
Sbjct: 1195 ML--------------DSDTEGEGDIAGTINPSVAMAIAGGPLAPGSRASISQGPPTASR 1240
Query: 1261 SGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALF 1320
+G +L +S ++LL C L++LK+ L
Sbjct: 1241 AGCALSAESS------------------------------RTLLACVLWVLKNTEPALLQ 1270
Query: 1321 TYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGM--------MHARLQQ--LGSL- 1369
+ + +L + +CL F+Y GK+ R M ARL++ LG++
Sbjct: 1271 RWATDLTLPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIG 1330
Query: 1370 -----------------DNSLTFNHSYGH----------SDADVLHQSLLEANIATEVCL 1402
++ + S H + ++ H++L+E N+ATE L
Sbjct: 1331 ARQEMVRRSRERSPFGNPENVRWRKSVTHWKQTSDRVDKTKDEMEHEALVEGNLATEASL 1390
Query: 1403 TALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYK 1462
LDTL + ++ ++ V V L L QS L++ R+L+ K
Sbjct: 1391 VVLDTLEIIV----QTVMLSEARESVLGAVLKVVLYSLGSAQSALFLQHGLATQRALVSK 1446
Query: 1463 FPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHL 1522
FP +E ++CA LC +L+ C S++S+IRT AS LY LMR NF+ +F R +
Sbjct: 1447 FPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEI--GHNFARVKM 1504
Query: 1523 QVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMA 1582
QV +S+S L+ ++SL I A D ++ ++F+ V+DL + +L
Sbjct: 1505 QVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDMGLRDSTFAEQVQDLMFNLHMILTD 1564
Query: 1583 TAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVT 1642
T +MKEH+ DPEML+DL Y +A+ Y +P+LR TWL +MA H + G+ +EAA C VH
Sbjct: 1565 TVKMKEHQEDPEMLIDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCMVHAA 1624
Query: 1643 ALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDV 1702
ALVAEYL E H H GC +F+ I+ N+ EE+++ +D+
Sbjct: 1625 ALVAEYLALLE---------DHRH-----------LPVGCVSFQNISSNVLEESAISDDI 1664
Query: 1703 GMQD-------VHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLA 1755
D HF E L+ LLEQ A YE + ++YK +IPI E RD+++LA
Sbjct: 1665 LSPDEEGFCSGKHFTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLA 1724
Query: 1756 HLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEY 1815
++ L A++K+ R+ GTYFRV F+G F D D +E+
Sbjct: 1725 AVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYG---------------AHFGDLDEQEF 1769
Query: 1816 IYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFF 1875
+YKEP +T L+EIS RL + Y+++FG + V++I+DS V+ LDS+ AYIQ+T+V P+F
Sbjct: 1770 VYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDSQKAYIQITYVEPYF 1829
Query: 1876 DEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRI 1935
D EL++R T F+R++ +R F+F PFT G+ G + EQ KR+T+L+ H FPY+K RI
Sbjct: 1830 DTYELKDRVTYFDRNYGLRTFLFCTPFTPDGRAHGELPEQHKRKTLLSTDHAFPYIKTRI 1889
Query: 1936 PVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAY 1995
V ++ T L P+EVAI++M KK EL D LQ+ LQGSV VN GPL
Sbjct: 1890 RVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEV 1949
Query: 1996 ARAFL----DDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKA 2051
A+ FL +D R+ NK++L F+ F + C AL N+ LI DQ EY E++
Sbjct: 1950 AQVFLAEIPEDPKLFRH-HNKLRL---CFKDFCKKCEDALRKNKALIGPDQKEYHRELER 2005
Query: 2052 NYREMAKELSEIMHEQL 2068
NY + + L ++ ++L
Sbjct: 2006 NYCRLREALQPLLTQRL 2022
Score = 55.8 bits (133), Expect = 4e-07
Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 16/165 (9%)
Query: 9 ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAK----------PKLIEPLDYENVI 58
A++E R F +++ AAE+R+ VS GS ++ +++EPLD+E+V+
Sbjct: 2 AASERRAFAHKINRT-VAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDFEDVL 60
Query: 59 VQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYN 118
+ + LR+++ FP DD + + R+ R +T P ++E V ++ Y
Sbjct: 61 LSRPPDAEPGPLRDLVEFPADDLELLLQPRECR---TTEPGIPKDEKLDAQVRAAVEMYI 117
Query: 119 SDWHLVNYKYEDYSGEFRQLPNKVVKLDK--LPVHVYEVDEEVDK 161
DW +V+ +Y+ S + + + + LP V+E D D+
Sbjct: 118 EDWVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDE 162
>gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]
Length = 2109
Score = 565 bits (1457), Expect = e-160
Identities = 372/1203 (30%), Positives = 584/1203 (48%), Gaps = 185/1203 (15%)
Query: 957 LKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNP 1016
L+ +WFFF++++KSM HL N K++ R RFP + + +V+ + I +F+ +
Sbjct: 974 LQQAWFFFELMVKSMVHHLYFNDKLEAPRKSRFPERFMDDIAALVSTIASDIVSRFQKDT 1033
Query: 1017 EASKNANHSLAVFIKRCFTFMDRGFVF-------KQINNYISCFAPGDPKTLFEYKFEFL 1069
E + N SLA F+ + MDRGFVF KQ+++ + ++ +P L + +FL
Sbjct: 1034 EMVERLNTSLAFFLNDLLSVMDRGFVFSLIKSCYKQVSSKL--YSLPNPSVLVSLRLDFL 1091
Query: 1070 RVVCNHEHYIPLNLPMPF-----------------GKGRIQRYQDLQLD--YSLTDEFCR 1110
R++C+HEHY+ LNLP G QD ++ + L+ F +
Sbjct: 1092 RIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQ 1151
Query: 1111 NHFLVGLLLREVGTALQEFRE----VRLIAISVLKNLLIKHSFDDRYASRSHQARIATLY 1166
H+L GL+L E+ L E + I+++ NLL H D RY+ +AR+A LY
Sbjct: 1152 QHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQIKARVAMLY 1211
Query: 1167 LPLFGLLIENVQRINVRDVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDL 1226
LPL G+++E V ++ T P + T S + + + +
Sbjct: 1212 LPLIGIIMETVPQLY-----------DFTETHNQRGRPIC--IATDDYESESGSMISQTV 1258
Query: 1227 LGAISGIASPYTTSTPNINSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLG 1286
AI+G + P T + L+++ SG ++E S
Sbjct: 1259 AMAIAGTSVPQLTRPGSF-----------LLTSTSGRQHTTFSAESS------------- 1294
Query: 1287 NSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALFTYWNKASTSELMDFFTISEVCLHQFQ 1346
+SLL+C L++LK+ + L ++ S +L + +C+ F+
Sbjct: 1295 --------------RSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFE 1340
Query: 1347 YMGKRYIARTGM--------MHARLQQ--LGSL--------------------------- 1369
Y GK+ R M A+L++ LGS+
Sbjct: 1341 YKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLGTYTIASPPERSP 1400
Query: 1370 -------DNSLTFNHSYGH----------SDADVLHQSLLEANIATEVCLTALDTLSLFT 1412
+L + H S A++ H++L++ N+ATE L LDTL +
Sbjct: 1401 SGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIVV 1460
Query: 1413 LAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRA 1472
+ ++ V V L + +QS L++ F R+L+ KFP +E
Sbjct: 1461 ----QTVSVTESKESILGGVLKVLLHSMACNQSAVYLQHCFATQRALVSKFPELLFEEET 1516
Query: 1473 DMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLI 1532
+ CA LC +L+ C+S + +IR+ AS LY LMR NF+ +F R +QV +S+S L+
Sbjct: 1517 EQCADLCLRLLRHCSSSIGTIRSHASASLYLLMRQNFEIGN--NFARVKMQVTMSLSSLV 1574
Query: 1533 ADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHEND 1592
++SL I A D ++ T+F V+DL + +L T +MKEH+ D
Sbjct: 1575 GTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQED 1634
Query: 1593 PEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRK 1652
PEML+DL Y +AK Y ++P+LR TWL +MA H + + +EAA C VH ALVAEYL+
Sbjct: 1635 PEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSML 1694
Query: 1653 EAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDV----- 1707
E ++ P GC F+ I+ N+ EE+++ +DV D
Sbjct: 1695 EDRKYLPV--------------------GCVTFQNISSNVLEESAVSDDVVSPDEEGICS 1734
Query: 1708 --HFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAY 1765
+F E L+ LLEQ A A YE + ++YK++IPI+E RD ++L+ ++ L A+
Sbjct: 1735 GKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAF 1794
Query: 1766 SKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPL 1825
SK+ R+ GTYFRV F+G F D D +E++YKEP +T L
Sbjct: 1795 SKIVHQSTGWERMFGTYFRVGFYGTK---------------FGDLDEQEFVYKEPAITKL 1839
Query: 1826 SEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKT 1885
+EIS RL Y ++FG + V++I+DS V+ LD AYIQ+T+V P+FD E+++R T
Sbjct: 1840 AEISHRLEGFYGERFGEDVVEVIKDSNPVDKCKLDPNKAYIQITYVEPYFDTYEMKDRIT 1899
Query: 1886 EFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDL 1945
F++++N+RRFM+ PFT G+ G + EQ KR+TILT H FPY+K R+ V ++ L
Sbjct: 1900 YFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIIL 1959
Query: 1946 NPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNT 2005
PIEVAI++M KK EL D LQ+ LQGSV VN GPL A+ FL + +
Sbjct: 1960 TPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPS 2019
Query: 2006 KRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMH 2065
L+ F+ F + C AL N+ LI DQ EYQ E++ NY + + L +++
Sbjct: 2020 DPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLIN 2079
Query: 2066 EQL 2068
++
Sbjct: 2080 RKI 2082
Score = 263 bits (671), Expect = 2e-69
Identities = 206/698 (29%), Positives = 338/698 (48%), Gaps = 137/698 (19%)
Query: 313 DSYLPELAKSAREAEI------KLKSESRVKLFYL--DPDAQKLDFSSAEPEVKSFEEKF 364
D+ LP L EI + KS +LF L PD ++ + P++ +E F
Sbjct: 204 DALLPNLLDRTPNEEIDRQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDIP--KEHF 261
Query: 365 GKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFS 424
G+R+LVKC L F ++ +EP F +L+L+D+K +KIS +F+ DLN
Sbjct: 262 GQRLLVKCLSLKFEIE-------------IEPIFASLALYDVKEKKKISENFYFDLNSEQ 308
Query: 425 VRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ 484
++ +L P P+ + + A IFS+T P D+FLV ++EKVLQ
Sbjct: 309 MKGLLRPHVP---------PAAITTLARSA--------IFSITYPSQDVFLVIKLEKVLQ 351
Query: 485 -GSITHCAEPYM--KSSDSSKVAQKVLK---NAKQACQRLGQYRMPFAWAARTLFK--DA 536
G I CAEPYM K +D++K +K+ K A Q CQRLG+YRMPFAW A L +
Sbjct: 352 QGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSS 411
Query: 537 SGNLDKNA-----------------RFSAI------------------------------ 549
+G+L++++ R S+I
Sbjct: 412 AGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTN 471
Query: 550 -YRQDSNKLSNDDMLKLLADFRKPEK-MAKLPVILGNLDITIDNVSSDFPNYVNSSYIPT 607
++Q+ ++LS++D+ K LAD R+P + +L I L I I + P+Y + +
Sbjct: 472 FFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPEN-PHYCLTPELLQ 530
Query: 608 KQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAIC 667
+ S+ T E+ EF P + P T Y N LY+YP+ L + +++ ARNI +
Sbjct: 531 VKLYPDSRVRPTREILEF-PARDVYV-PNTTYRNLLYIYPQSLNFANRQG--SARNITVK 586
Query: 668 IEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHH 727
++F E+ S + I+G+ F++ A+ AV++H+++P+F++EIK++LP L + HH
Sbjct: 587 VQFMYG-EDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHH 645
Query: 728 LLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLG 787
LL TF+HVSC K+ +ET VGY+W+P+L++GR+ T + +PVS P
Sbjct: 646 LLFTFYHVSCQQ------KQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPP--QA 697
Query: 788 YQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG------ 841
Y L P +KWVD K + + VS+++TQD +L FF +
Sbjct: 698 YSVLSPEVPL-PGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHLFPVRI 756
Query: 842 ------AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTR-------------A 882
L NEL + +L++ + ++ FL +L++L ++ R A
Sbjct: 757 GDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVIRPPVIAGQIVNLGQA 816
Query: 883 TQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 920
+ E +A + R+ ++ + G S L SY+ Y ++
Sbjct: 817 SFEAMASIINRLHKNLEGNHDQHGRNSLLASYIHYVFR 854
Score = 64.7 bits (156), Expect = 9e-10
Identities = 50/170 (29%), Positives = 77/170 (45%), Gaps = 26/170 (15%)
Query: 11 AETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAK----------------PKLIEPLDY 54
AE R F + +S+ AAE+R+ +S GS L K + ++P+D
Sbjct: 2 AERRAFAQKISRT-VAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDL 60
Query: 55 ENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECI 114
E+ ++ + + LR+++ FP DD + R R + S VP EE V +CI
Sbjct: 61 EDYLITHPLAVDSGPLRDLIEFPPDDIEVVYSPRDCRTLVSAVP---EESEMDPHVRDCI 117
Query: 115 KTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDK----LPVHVYEVDEEVD 160
++Y DW +V KY F PN + K + LP V+E DE D
Sbjct: 118 RSYTEDWAIVIRKYHKLGTGFN--PNTLDKQKERQKGLPKQVFESDEAPD 165
>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
Length = 2099
Score = 515 bits (1327), Expect = e-145
Identities = 384/1230 (31%), Positives = 583/1230 (47%), Gaps = 196/1230 (15%)
Query: 921 AEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSK 980
A P AS+ K HEEL M + + + KY+WFFF++L+KSMAQH+ K
Sbjct: 950 AAPRPASK-KHFHEELALQMVV-----STGMVRETVFKYAWFFFELLVKSMAQHVHNMDK 1003
Query: 981 VKLLRNQRFPASYHHAVETVVNMLMPHITQKF----RDNPEASKNANHSLAVFIKRCFTF 1036
R RF + + T+VN++ I ++N +A K N SLA F+ +
Sbjct: 1004 RDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEK-MNISLAFFLYDLLSL 1062
Query: 1037 MDRGFVFKQINNYISCFAP--GDPKTLFEYKFEFLRVVCNHEHYIPLNL----------- 1083
MDRGFVF I +Y S + + TL + EFLR++C+HEHY+ LNL
Sbjct: 1063 MDRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTS 1122
Query: 1084 PMPF----GKGRIQRYQDLQLD--YSLTDEFCRNHFLVGLLLREVGTAL----QEFREVR 1133
P P +QD ++ + LT E+ + HFL GLL E+ AL + +V+
Sbjct: 1123 PCPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQ 1182
Query: 1134 LIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAG 1193
A+S + +L ++ D+ P V
Sbjct: 1183 RKAVSAIHSL------------------------------------LSSHDLDPRCVKPE 1206
Query: 1194 MTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSR 1253
+ VK +L LP V ++ D L + T S +
Sbjct: 1207 VKVKIAALYLPLVGIIL--------------DALPQLCDFTVADTRRYRTSGSDEEQEGA 1252
Query: 1254 GSLISTDS----GNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLY 1309
G++ + GN+ + S S ++Q + L R +L++CFL+
Sbjct: 1253 GAINQNVALAIAGNNFNLKTSGIVLSSLPYKQYNMLNADTTR----------NLMICFLW 1302
Query: 1310 ILKSMSDDALFTYW-NKASTSELMDFFTISEVCLHQFQYMGKRYI--------------- 1353
I+K+ +D +L W +++L + +C+ F+Y GK+
Sbjct: 1303 IMKN-ADQSLIRKWIADLPSTQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVK 1361
Query: 1354 ------------ARTGMMHARL---QQLGSLDNSLTFNHSYGH----------SDADVLH 1388
AR MM R + L+ +L + H + A++
Sbjct: 1362 ARLEEALLRGEGARGEMMRRRAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQ 1421
Query: 1389 QSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETA 1448
++L+ N+ATE L LD A D L+ V V + L QS T
Sbjct: 1422 EALISGNLATEAHLIILDMQENIIQASSALDCKDS----LLGGVLRVLVNSLNCDQSTTY 1477
Query: 1449 LKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNN 1508
L + F LR+LI KF +E + C LC+++L C+S + R++A LY LMR +
Sbjct: 1478 LTHCFATLRALIAKFGDLLFEEEVEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFS 1537
Query: 1509 FDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSD 1568
F T +F R +QV +S++ L+ ++SL I + D ++ T F +
Sbjct: 1538 FGATS--NFARVKMQVTMSLASLVGRAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQ 1595
Query: 1569 VKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKN 1628
V++L + ++L T +M+E + DPEML+DL Y +AKSY ++P+LR TWL +MA H K
Sbjct: 1596 VEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKK 1655
Query: 1629 GDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVI 1688
+EAAMC VH ALVAEYL+ E + P G +F+ I
Sbjct: 1656 KCYTEAAMCLVHAAALVAEYLSMLEDHSYLPV--------------------GSVSFQNI 1695
Query: 1689 TPNIDEEASMMEDVGMQDV-------HFNEDVLMELLEQCADGLWKAERYELIADIYKLI 1741
+ N+ EE+ + ED D +F E L+ LLEQ A+ YE + ++YKL+
Sbjct: 1696 SSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLV 1755
Query: 1742 IPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSET 1801
IPI E R+F +L + L RA+ + H +R+ GTYFRV FFG
Sbjct: 1756 IPILEAHREFRKLTLTHSKLQRAFDSIVNKDH--KRMFGTYFRVGFFGSK---------- 1803
Query: 1802 DVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDS 1861
F D D +E++YKEP +T L EIS RL Y FG+E V++I+DS V+ LD
Sbjct: 1804 -----FGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDP 1858
Query: 1862 KYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTI 1921
AYIQ+T V P+FDE E+++R T FE++ N+RRFM+ PFT G+ +G + EQ +R T+
Sbjct: 1859 NKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTV 1918
Query: 1922 LTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQ 1981
LT +H FPY+K RI V+ + L PIEVAI++M KK +L + D LQ+ LQ
Sbjct: 1919 LTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQ 1978
Query: 1982 GSVSVQVNAGPLAYARAFLDD--TNTKRY-PDNKVKLLKEVFRQFVEACGQALAVNERLI 2038
GSV VN GPL A+ FL + + K Y NK++L F++F+ CG+A+ N+RLI
Sbjct: 1979 GSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRL---CFKEFIMRCGEAVEKNKRLI 2035
Query: 2039 KEDQLEYQEEMKANYREMAKELSEIMHEQL 2068
DQ EYQ+E+K NY ++ + L ++ ++
Sbjct: 2036 TADQREYQQELKKNYNKLKENLRPMIERKI 2065
Score = 273 bits (698), Expect = 1e-72
Identities = 197/622 (31%), Positives = 302/622 (48%), Gaps = 110/622 (17%)
Query: 324 REAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCV 383
++ E ++ + +LF L P + D P + +E G RILVK L F ++
Sbjct: 224 KQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIE--- 280
Query: 384 AENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQS 443
+EP F +++L+D+K +KIS +FH DLN + L +P++
Sbjct: 281 ----------IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSV------- 323
Query: 444 PSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPY--MKSSDS 500
AA + +FSVT P DI+LV +IEKVLQ G I CAEPY +K SD
Sbjct: 324 ----------AASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDG 373
Query: 501 SKVAQKVLKNAKQA---CQRLGQYRMPFAWAA---------------------------- 529
K +K+ K QA CQRLG+YRMPFAWA
Sbjct: 374 GKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVGRSSV 433
Query: 530 ---RTL-----FKDASGNLDKNA----------RFSAIYRQDSNKLSNDDMLKLLADFRK 571
RTL + + +L++N S+ ++Q+ ++LS++D+ K LAD+++
Sbjct: 434 GERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLADYKR 493
Query: 572 PEKMAK-LPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIP 630
+ + + I G L + I + +P K F ++T E+ EF P
Sbjct: 494 SSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPE-NRTRPHKEILEF-PTRE 551
Query: 631 KHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGG 690
+ P+T+Y N LYVYP+ L + ++ A ARNI I I+F E+ S + I+G+ G
Sbjct: 552 VYV-PHTVYRNLLYVYPQRLNFVNK--LASARNITIKIQFM-CGEDASNAMPVIFGKSSG 607
Query: 691 PVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDV 750
P F + + AV +H+++P+FY+E+KI+LP +L HHLL TF+H+SC S
Sbjct: 608 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGAS------ 661
Query: 751 VETQVGYSWLPLLKDGRVVTSEQHIPVS-ANLPSGYLGYQELGMGRHYGPEIKWVDGGKP 809
VET +GYSWLP+L + R+ T +PV+ LP Y + + P IKW +G K
Sbjct: 662 VETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQ-NPPIKWAEGHKG 720
Query: 810 LLKISTHLVSTVYTQDQHLHNFFQYCQKTES-------------GAQALGNELVKYLKSL 856
+ I VS+V+TQD HL FF C ES AL +EL + L
Sbjct: 721 VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL 780
Query: 857 HAMEGHVMIAFLPTILNQLFRV 878
++ ++ FL +L++LF++
Sbjct: 781 NSSRLEPLVLFLHLVLDKLFQL 802
Score = 39.7 bits (91), Expect = 0.031
Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 18/169 (10%)
Query: 9 ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKL---IEPLDYENVIVQKKTQI 65
+SAE RK + P RQS+S G L P+ +EP+D+E +++ +
Sbjct: 20 SSAEIRK--QFTLPPNLGQYHRQSIS--TSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSL 75
Query: 66 LNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSL--FVTECIKTYNSDWHL 123
+E+ F DD ++ C T+ EE L V +C++TY +W +
Sbjct: 76 DVQLAQELGDFTDDDLDVVFTPKE----CRTLQPSLPEEGVELDPHVRDCVQTYIREWLI 131
Query: 124 VNYKYE---DYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLG 169
VN K + + G F++ ++ LP +E E ++ E AA G
Sbjct: 132 VNRKNQGSPEICG-FKKTGSRKDFHKTLPKQTFE-SETLECSEPAAQAG 178
>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
Length = 2030
Score = 85.1 bits (209), Expect = 6e-16
Identities = 72/324 (22%), Positives = 131/324 (40%), Gaps = 26/324 (8%)
Query: 1745 YEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVE 1804
YE D++ L+ + Y + E +RL +FRV F+G+ + +
Sbjct: 1321 YESLYDYQSLSWIRKMEASYYDNIMEQ----QRLEPEFFRVGFYGRKFPFFLRN------ 1370
Query: 1805 GFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYA 1864
KEY+ + L QR+L + ++ D+ YA
Sbjct: 1371 --------KEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYA 1422
Query: 1865 YIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGK-RQGGVEEQCKRRTILT 1923
+ + + +R F R +N+R+F ++ PF + K ++ + RT LT
Sbjct: 1423 VTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERTTLT 1482
Query: 1924 AIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIK-----LQL 1978
H P + + V + +++P+E AI + K ELR L S + + L +
Sbjct: 1483 LTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRSLISQYQHKQVHGNINLLSM 1542
Query: 1979 KLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDN--KVKLLKEVFRQFVEACGQALAVNER 2036
L G + VN G Y AF D ++P + K+ LKE+ ++ V G LAV+E+
Sbjct: 1543 CLNGVIDAAVNGGIARYQEAFFDKDYINKHPGDAEKITQLKELMQEQVHVLGVGLAVHEK 1602
Query: 2037 LIKEDQLEYQEEMKANYREMAKEL 2060
+ + +++ ++ M L
Sbjct: 1603 FVHPEMRPLHKKLIDQFQMMRASL 1626
Score = 39.7 bits (91), Expect = 0.031
Identities = 57/224 (25%), Positives = 93/224 (41%), Gaps = 34/224 (15%)
Query: 677 DSQPLK-CIYGRPGGPVFTRSAFAA-VLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFH 734
D + LK CI G P RS++ + VL+H +P + + IK+ +P HL F H
Sbjct: 454 DGEILKDCISLGSGEP--NRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRH 511
Query: 735 VSCDNSSKGSTKKRDVVETQVGYSWLPLLK-DGRVVTSEQH--------IPVSANLPSGY 785
C KG K G+++ L++ DG ++ + H + N + Y
Sbjct: 512 --CSTKDKGEKK-------LFGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNNHALY 562
Query: 786 LGYQELGMGRHYGPEIK----WVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG 841
LG + P I + K IST L ST TQ+ L ++
Sbjct: 563 LGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKW------- 615
Query: 842 AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQE 885
+A + ++ L L + G ++ FL IL+ LF +L T++
Sbjct: 616 -KAFPDRIMDVLGRLRHVSGEEIVKFLQDILDTLFVILDDNTEK 658
>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
Length = 1870
Score = 68.9 bits (167), Expect = 5e-11
Identities = 72/364 (19%), Positives = 152/364 (41%), Gaps = 26/364 (7%)
Query: 1707 VHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRR-DFERLAHLYDTLHRAY 1765
V+ +++ +L ++ K + +E + K + YE + D+E L +L Y
Sbjct: 1290 VYTQQELKEKLYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFY 1349
Query: 1766 SKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPL 1825
+ + M R YF V ++GQ GF K +IY+ +
Sbjct: 1350 ENIIKAM----RPQPEYFAVGYYGQ--------------GFPSFLRNKIFIYRGKEYERR 1391
Query: 1826 SEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKT 1885
+ S RLL + + + + K +PK + V + P + +K + E+
Sbjct: 1392 EDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQIL 1451
Query: 1886 EFERSHNIRRFMFEMPFTQTGKRQGG-VEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTD 1944
+ R++ +++F + PF + K RT T + FP + K V +
Sbjct: 1452 NYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQISTEE 1511
Query: 1945 LNPIEVAIDEM---SKKVAE-LRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFL 2000
++P+E AI+ M +++++ ++Q + + L + L G V V G Y +AF
Sbjct: 1512 ISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKAFF 1571
Query: 2001 DDTNTKRYPDN--KVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAK 2058
+ + +P++ KV+LLK + + + + ++ + E E + + +RE+ +
Sbjct: 1572 TEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKE 1631
Query: 2059 ELSE 2062
++ +
Sbjct: 1632 KVEK 1635
Score = 40.8 bits (94), Expect = 0.014
Identities = 72/350 (20%), Positives = 139/350 (39%), Gaps = 53/350 (15%)
Query: 641 NHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAA 700
N +YV + ++D K +N+ + + D EE K I+ PG S + +
Sbjct: 444 NDIYVTLIHGEFDKGKK-KTPKNVEVTMSVHD--EEGKLLEKAIH--PGAGYEGISEYKS 498
Query: 701 VLHHH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSW 759
V+++ + P +Y+ +K+ + + + H+ TF H + S + RD E G ++
Sbjct: 499 VVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRH-------RSSQETRDKSERAFGVAF 551
Query: 760 LPLLK-DGRVVTSEQHIPV--------------SANLPSGYLGYQ--ELGMGRHYGPEIK 802
+ L+ DG + +H V LP + + EL ++
Sbjct: 552 VKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFTP 611
Query: 803 WVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGH 862
D K +I+T + ST TQ+ L + +++ + LK L ++G
Sbjct: 612 SKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQN--------IKHNLKKLMEVDGG 663
Query: 863 VMIAFLPTILNQLFRVLTRATQEE--------VAVNVTRVIIHVVAQCHEEGLESHL--- 911
++ FL L+ LF ++ + E V + +I + Q LE+++
Sbjct: 664 EIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYIYKH 723
Query: 912 ----RSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLL 957
+YVK + YVA+ + EL + LK F+ +++L
Sbjct: 724 FSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVL 773
>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
Length = 1966
Score = 68.6 bits (166), Expect = 6e-11
Identities = 65/329 (19%), Positives = 137/329 (41%), Gaps = 37/329 (11%)
Query: 1745 YEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVE 1804
YE D+ L+ + Y K+ + +RL +FRV F+G+ + +
Sbjct: 1283 YESYYDYRNLSKMRMMEASLYDKIMDQ----QRLEPEFFRVGFYGKKFPFFLRN------ 1332
Query: 1805 GFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYA 1864
KE++ + L QR+L + +Q + + + ++
Sbjct: 1333 --------KEFVCRGHDYERLEAFQQRMLNEFPHAIA------MQHANQPDETIFQAEAQ 1378
Query: 1865 YIQVTHVIPFFDEKELQERK------TEFERSHNIRRFMFEMPFTQ-TGKRQGGVEEQCK 1917
Y+Q+ V P + +E+ +R+ F + ++I +F ++ PF + T ++ +
Sbjct: 1379 YLQIYAVTPIPESQEVLQREGVPDNIKSFYKVNHIWKFRYDRPFHKGTKDKENEFKSLWV 1438
Query: 1918 RRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIK-- 1975
RT L + P + + V + +++P+E AI+ + K +L+ L S + ++
Sbjct: 1439 ERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQTRQMQNI 1498
Query: 1976 --LQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDN--KVKLLKEVFRQFVEACGQAL 2031
L + L G + VN G Y AF +P++ K+ L+E+ + + L
Sbjct: 1499 NPLTMCLNGVIDAAVNGGVSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQAQILEFGL 1558
Query: 2032 AVNERLIKEDQLEYQEEMKANYREMAKEL 2060
AV+E+ + +D +++ + M L
Sbjct: 1559 AVHEKFVPQDMRPLHKKLVDQFFVMKSSL 1587
Score = 45.8 bits (107), Expect = 4e-04
Identities = 55/248 (22%), Positives = 102/248 (41%), Gaps = 31/248 (12%)
Query: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720
ARN+ + + DS Q LK G + VL+H+ +P + + +K+ +P
Sbjct: 421 ARNVEVTMFIVDSS---GQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPV 477
Query: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL-KDGRVVTSEQHIPV-- 777
H+ F H C KG K G+S++PL+ +DGR + H +
Sbjct: 478 DKFRGAHIRFEFRH--CSTKEKGEKK-------LFGFSFVPLMQEDGRTLPDGTHELIVH 528
Query: 778 ----SANL--PSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNF 831
+ NL + YL G G + + K I++ L ST TQ+ + +
Sbjct: 529 KCEENTNLQDTTRYLKL-PFSKGIFLGNNNQAMKATKESFCITSFLCSTKLTQNGDMLDL 587
Query: 832 FQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNV 891
++ + +++ L L ++G ++ FL L+ LF +L +Q + V
Sbjct: 588 LKW--------RTHPDKITGCLSKLKEIDGSEIVKFLQDTLDTLFGILDENSQ-KYGSKV 638
Query: 892 TRVIIHVV 899
++H++
Sbjct: 639 FDSLVHII 646
>gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
Length = 1830
Score = 65.5 bits (158), Expect = 5e-10
Identities = 75/384 (19%), Positives = 153/384 (39%), Gaps = 37/384 (9%)
Query: 1693 DEE-ASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRR-D 1750
DE+ AS + G Q + + L E K + +E + K + YE D
Sbjct: 1255 DEQCASQVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFD 1314
Query: 1751 FERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDE 1810
+E L+ + Y + +++ R YF V ++GQ GF
Sbjct: 1315 YELLSQNLIQQAKFYESIMKIL----RPKPDYFAVGYYGQ--------------GFPSFL 1356
Query: 1811 DGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTH 1870
K +IY+ + + +L+ + + D K P + V
Sbjct: 1357 RNKVFIYRGKEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLD 1416
Query: 1871 VIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCK------RRTILTA 1924
P F K + ++ F +S+ ++RF + P R+G V+ + + RT
Sbjct: 1417 EHPRFKNKPVPDQIINFYKSNYVQRFHYSRPV-----RRGTVDPENEFASMWIERTSFVT 1471
Query: 1925 IHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMS----KKVAELRQLCSSAEVDMIKLQLKL 1980
+ P + + V++ T ++P+E AI+ MS K + + Q S + + L + L
Sbjct: 1472 AYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLL 1531
Query: 1981 QGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKL--LKEVFRQFVEACGQALAVNERLI 2038
G V V G Y +AF + + +P+++ KL LK++ + G + ++E+ +
Sbjct: 1532 NGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRV 1591
Query: 2039 KEDQLEYQEEMKANYREMAKELSE 2062
++ + + M+ ++ + ++ +
Sbjct: 1592 SDNLRPFHDRMEECFKNLKMKVEK 1615
Score = 39.3 bits (90), Expect = 0.040
Identities = 67/332 (20%), Positives = 130/332 (39%), Gaps = 54/332 (16%)
Query: 699 AAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYS 758
+ V + + P + + +K+ +P + ++ HL F H + S + +D E S
Sbjct: 478 SVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRH-------RSSLESKDKGEKNFAMS 530
Query: 759 WLPLLK-DGRVVTSEQHIPVSANLPSGYL----GYQELGMGRHY--------GPEIKWVD 805
++ L+K DG + H V S + Y L RH+ V
Sbjct: 531 YVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVG 590
Query: 806 G----GKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEG 861
G + + IST + ST TQ+ L ++ K + L + L+ L ++G
Sbjct: 591 GLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQL--------LQENLEKLKIVDG 642
Query: 862 HVMIAFLPTILNQLFRVLTRATQ-EEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 920
++ FL L+ LF ++ +Q +E + V +I+++ + R + +
Sbjct: 643 EEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIAD-------RKFQHFNTV 695
Query: 921 AEPYVASEYKT--VHEELTKSMTTILKPSA------DFLTSNKLLKYSWFFFDVLIKSMA 972
E Y+ + +++L + T L S+ L + K L+Y F F V +++
Sbjct: 696 LEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYV-FKFIVRSRTLF 754
Query: 973 QHLIENSKVKLLRNQRFPASYHHAVETVVNML 1004
L E + F S E++ N++
Sbjct: 755 SQLYEGKE-----QMEFEESMRRLFESINNLM 781
>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
Length = 1865
Score = 65.1 bits (157), Expect = 7e-10
Identities = 80/387 (20%), Positives = 153/387 (39%), Gaps = 58/387 (14%)
Query: 1709 FNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRR------------------- 1749
++EDV + L Q DG + +L +Y+ II ++K +
Sbjct: 1249 WSEDVCVAHLTQ-RDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENE 1307
Query: 1750 --DFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFF 1807
D+E+L+ L + Y + +V+ R YF V ++GQ GF
Sbjct: 1308 MFDYEQLSELLKKQAQFYENIVKVI----RPKPDYFAVGYYGQ--------------GFP 1349
Query: 1808 EDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQ 1867
GK +IY+ + + RLL + + + D K +P YIQ
Sbjct: 1350 TFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ------YIQ 1403
Query: 1868 VTHVIPFFD-----EKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGG-VEEQCKRRTI 1921
V P D + + E+ F R + ++RF + P + K RTI
Sbjct: 1404 CFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTI 1463
Query: 1922 LTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMS----KKVAELRQLCSSAEVDMIKLQ 1977
T + P + + V +++P+E AI+ M K + ++Q + + L
Sbjct: 1464 YTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLS 1523
Query: 1978 LKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPD--NKVKLLKEVFRQFVEACGQALAVNE 2035
+ L G V V G Y +AF D + +P+ K++ LK++ + + + ++
Sbjct: 1524 MLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHG 1583
Query: 2036 RLIKEDQLEYQEEMKANYREMAKELSE 2062
+ E + E M+A ++++ +++ +
Sbjct: 1584 DKVTEALRPFHERMEACFKQLKEKVEK 1610
Score = 45.8 bits (107), Expect = 4e-04
Identities = 75/342 (21%), Positives = 146/342 (42%), Gaps = 43/342 (12%)
Query: 645 VYPKYLKYDSQK-SFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703
+Y ++ D K S A+N+ + + D ED + L+ + PG S + +V++
Sbjct: 428 IYVTLVQGDFDKGSKTTAKNVEVTVSVYD---EDGKRLEHVIF-PGAGDEAISEYKSVIY 483
Query: 704 HH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPL 762
+ + P +++ +K+ +P + + HL TF H S +S S K + ++
Sbjct: 484 YQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTT 543
Query: 763 LKDGR----VVTSE----QHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDG---GKPLL 811
L+DG V +E + +LPS +E G G ++ + K
Sbjct: 544 LRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSA-TGKSMQSLGSCTISKDSF 602
Query: 812 KISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTI 871
+IST + ST TQ+ L ++ T + L + L+ L ++G ++ FL
Sbjct: 603 QISTLVCSTKLTQNVDLLGLLKWRSNT--------SLLQQNLRQLMKVDGGEVVKFLQDT 654
Query: 872 LNQLFRVLTRATQEE----VAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKA------ 921
L+ LF ++ ++ E + + II ++A + L +Y+K + A
Sbjct: 655 LDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTK 714
Query: 922 -----EPYV-ASEYKTVHEELTKSMTTILKPSADFLTSNKLL 957
+ YV +E V+E+L K+M L+ F+ +++L
Sbjct: 715 LTKVLKNYVDGAEKPGVNEQLYKAMKA-LESIFKFIVRSRIL 755
>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
sapiens]
Length = 645
Score = 45.8 bits (107), Expect = 4e-04
Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 22/113 (19%)
Query: 177 KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCM 236
K GWL K ++++++R+F L + L +YKDE+ +K P+G ++L C
Sbjct: 49 KMGWLKKQRS------IVKNWQQRYFVL-----RAQQLYYYKDEEDTK-PQGCMYLPGCT 96
Query: 237 --GVVQN-NKVRRFAFEL-------KMQDKSSYLLAADSEVEMEEWITILNKI 279
+ N + +F FE+ + SY+L A S+ EMEEW+ L ++
Sbjct: 97 IKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRV 149
>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
sapiens]
Length = 638
Score = 45.8 bits (107), Expect = 4e-04
Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 22/113 (19%)
Query: 177 KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCM 236
K GWL K ++++++R+F L + L +YKDE+ +K P+G ++L C
Sbjct: 42 KMGWLKKQRS------IVKNWQQRYFVL-----RAQQLYYYKDEEDTK-PQGCMYLPGCT 89
Query: 237 --GVVQN-NKVRRFAFEL-------KMQDKSSYLLAADSEVEMEEWITILNKI 279
+ N + +F FE+ + SY+L A S+ EMEEW+ L ++
Sbjct: 90 IKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRV 142
>gi|55741447 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 1 [Homo sapiens]
Length = 1364
Score = 44.7 bits (104), Expect = 0.001
Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 17/120 (14%)
Query: 164 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEK-I 222
D LG + + K G+L K M S + +++KRR+F L Q + +YK +
Sbjct: 570 DGLGLGGES--LEKSGYLLK--MGSQV----KTWKRRWFVLRQ-----GQIMYYKSPSDV 616
Query: 223 SKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQL 282
++P+G + L+S +V+ + F + +K +Y L ADS +EEWI +L +L++
Sbjct: 617 IRKPQGQVDLNSRCQIVRGEGSQTFQL---ISEKKTYYLTADSPSLLEEWIRVLQSLLKV 673
>gi|217416392 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 2 [Homo sapiens]
Length = 1493
Score = 44.3 bits (103), Expect = 0.001
Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 20/142 (14%)
Query: 148 LPVHVYEVDEEVDKDED-------AASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRR 200
+P Y D E + E ++S + + K G+L K +S ++S+KRR
Sbjct: 670 IPPDAYSTDTEYSQPEQKLPKTCSSSSDNGKNEPLEKSGYLLK------MSGKVKSWKRR 723
Query: 201 FFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYL 260
+F L G L + + ++P+G I L + +++ + + +K +Y
Sbjct: 724 WFVL----KGGELLYYKSPSDVIRKPQGHIELSASCSILRGDNKQTVQLTT---EKHTYY 776
Query: 261 LAADSEVEMEEWITILNKILQL 282
L ADS +EEWI +L +L++
Sbjct: 777 LTADSPNILEEWIKVLQNVLRV 798
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 42.4 bits (98), Expect = 0.005
Identities = 60/225 (26%), Positives = 95/225 (42%), Gaps = 35/225 (15%)
Query: 156 DEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLN 215
D +++ + DAA+ GI G+L+K N+ +++ RR+F IQ Y
Sbjct: 254 DSKLEYNVDAAN------GIVMEGYLFKRASNA-----FKTWNRRWFS-IQNNQLVYQKK 301
Query: 216 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITI 275
F + + E + C + RRF FE+ KS +L ADSE + WI
Sbjct: 302 FKDNPTVVVEDLRLCTVKHCEDIE-----RRFCFEVVSPTKSC-MLQADSEKLRQAWI-- 353
Query: 276 LNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESR 335
K +Q + A +EK GD E ++ +GS LDS E LK ES
Sbjct: 354 --KAVQTSIATAYREK--GDESEKLDKKSSPSTGS-LDS-------GNESKEKLLKGESA 401
Query: 336 VKLFYLDP-DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNL 379
++ P +A D A+P S G + ++C+ + +L
Sbjct: 402 LQRVQCIPGNASCCDCGLADPRWASI--NLGITLCIECSGIHRSL 444
>gi|24432056 hypothetical protein LOC144717 [Homo sapiens]
Length = 249
Score = 42.0 bits (97), Expect = 0.006
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 13/101 (12%)
Query: 179 GWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSC-MG 237
G+LYK A ++ RR+F L N+ FY ++ S+EP G I L+ C +
Sbjct: 22 GFLYKKGGRHA------AYHRRWFVL------RGNMLFYFEDAASREPVGVIILEGCTVE 69
Query: 238 VVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNK 278
+V+ + FA +Y+LAA+S+ ME W+ L++
Sbjct: 70 LVEAAEEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSR 110
>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
Length = 1242
Score = 40.8 bits (94), Expect = 0.014
Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 17/123 (13%)
Query: 195 RSFKRRFFHLIQLGD--GSYNLNFYKDEKI----SKEPKGSIFLDSCMGVVQNNKVRRFA 248
+S +RFF L + G L +Y++EK S PK SI L+SC + + +
Sbjct: 23 KSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKH 82
Query: 249 FELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGS 308
+ +AADSE E + W ++A +Q H D + G
Sbjct: 83 LVALYTRDEHFAIAADSEAEQDSW-----------YQALLQLHNRAKGHHDGAAALGAGG 131
Query: 309 GSG 311
G G
Sbjct: 132 GGG 134
>gi|238908495 similar to pleckstrin homology domain protein (5V327)
[Homo sapiens]
Length = 506
Score = 40.4 bits (93), Expect = 0.018
Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 21/183 (11%)
Query: 197 FKRRFFHLIQLGDGSYNLNFYKDEKISKE--------PKGSIFLDSCMGVVQNNKVRRFA 248
+ RRFF + + S+ L + + EK S E PKG I L C+ + +A
Sbjct: 47 WSRRFFIIKE----SFLLYYSESEKKSFETNKYFNIHPKGVIPLGGCLVEPKEEPSMPYA 102
Query: 249 FELKMQD-KSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEG 307
++ QD + LLAA+SE E +W+ +L + ++ ++ A + S E +
Sbjct: 103 MKISHQDFHGNILLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKE 162
Query: 308 SGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP--DAQKLDFSSAEPEVKSFEEKFG 365
LD + E E+ L+ E R +L L+ +A+K F E++ +E+
Sbjct: 163 KQEYLDKLMEE------TEELCLQREQREELERLNQVLEAEKQQFEEVVQELRMEQEQIK 216
Query: 366 KRI 368
+ +
Sbjct: 217 REL 219
>gi|219689123 pleckstrin homology domain containing, family A member
5 isoform 2 [Homo sapiens]
Length = 1105
Score = 40.4 bits (93), Expect = 0.018
Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 14/102 (13%)
Query: 175 ITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDS 234
+ + GWLYK + S M+ +K+R+F L L L +Y+DEK + GSI L S
Sbjct: 62 VVRRGWLYKQD-----STGMKLWKKRWFVLSDLC-----LFYYRDEK-EEGILGSILLPS 110
Query: 235 ---CMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWI 273
+ +++ R++AF+ + +Y D+ EME W+
Sbjct: 111 FQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWM 152
>gi|19923493 pleckstrin homology domain containing, family A member
5 isoform 1 [Homo sapiens]
Length = 1116
Score = 40.4 bits (93), Expect = 0.018
Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 14/102 (13%)
Query: 175 ITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDS 234
+ + GWLYK + S M+ +K+R+F L L L +Y+DEK + GSI L S
Sbjct: 170 VVRRGWLYKQD-----STGMKLWKKRWFVLSDLC-----LFYYRDEK-EEGILGSILLPS 218
Query: 235 ---CMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWI 273
+ +++ R++AF+ + +Y D+ EME W+
Sbjct: 219 FQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWM 260
>gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [Homo
sapiens]
Length = 358
Score = 39.7 bits (91), Expect = 0.031
Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 13/95 (13%)
Query: 216 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFA-----FELKMQDKSSYLLAADSEVEME 270
+Y +EK SK+PKG+ FL GV +RR + FEL QD+ SY A S E
Sbjct: 142 YYANEK-SKQPKGT-FLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEAR 199
Query: 271 EWITILNKILQ------LNFEAAMQEKRNGDSHED 299
+W+ ++ +L+ + +E +E+ ++++D
Sbjct: 200 DWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDD 234
>gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [Homo
sapiens]
Length = 359
Score = 39.7 bits (91), Expect = 0.031
Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 13/95 (13%)
Query: 216 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFA-----FELKMQDKSSYLLAADSEVEME 270
+Y +EK SK+PKG+ FL GV +RR + FEL QD+ SY A S E
Sbjct: 142 YYANEK-SKQPKGT-FLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEAR 199
Query: 271 EWITILNKILQ------LNFEAAMQEKRNGDSHED 299
+W+ ++ +L+ + +E +E+ ++++D
Sbjct: 200 DWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDD 234
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 39.3 bits (90), Expect = 0.040
Identities = 46/170 (27%), Positives = 70/170 (41%), Gaps = 26/170 (15%)
Query: 144 KLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFH 203
K D HV +E+ +E SL GG+ G L+K N+ +++ RR+F
Sbjct: 235 KRDMEQRHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRASNA-----FKTWSRRWF- 288
Query: 204 LIQLGDGSYNLNFYKDEKISKEPKGSIF--LDSCMGVVQNNKVRRFAFELKMQDKSSYLL 261
IQ Y +K K+P + L C + + RRF FE+ KS LL
Sbjct: 289 TIQSNQLVY-------QKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSC-LL 340
Query: 262 AADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSG 311
ADSE ++ W++ + + F A D+ + G GSG
Sbjct: 341 QADSERLLQLWVSAVQSSIASAFSQARL----------DDSPRGPGQGSG 380
>gi|18105042 GRB2-associated binding protein 2 isoform a [Homo
sapiens]
Length = 676
Score = 38.9 bits (89), Expect = 0.053
Identities = 48/185 (25%), Positives = 89/185 (48%), Gaps = 29/185 (15%)
Query: 173 GGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYN---LNFYKDEKISKEPKGS 229
G + GWL K + ++K+R+F +++ G S + L +YK++ SK+P
Sbjct: 5 GDVVCTGWLRKSPPEKKLR--RYAWKKRWF-ILRSGRMSGDPDVLEYYKNDH-SKKPLRI 60
Query: 230 IFLDSC----MGVVQNNKVRR--FAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283
I L+ C G+ N K + F F++K +++ YL+ A++E +M +W+ + +I N
Sbjct: 61 INLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV-AETEEDMNKWVQSICQICGFN 119
Query: 284 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKS-----ESRVKL 338
Q + + DS + + +G G S EL+ S++ + KS S+ L
Sbjct: 120 -----QAEESTDSLRN-----VSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTL 169
Query: 339 FYLDP 343
F +P
Sbjct: 170 FTFEP 174
>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
Length = 2390
Score = 38.5 bits (88), Expect = 0.069
Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 14/127 (11%)
Query: 213 NLNFYKDEKISK-----EPKGSIFLDSCMGVVQ-NNKVRRFAFELKMQDKSSYLLAADSE 266
+L FYKD K + + + L G V + + R+ F+L +QD YL A E
Sbjct: 2254 SLGFYKDAKAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDE 2313
Query: 267 VEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREA 326
EM W+ ++N + A +G+ E S G + +P ++ E
Sbjct: 2314 AEMSSWLRVVNAAI------ATASSASGEPEEPVVPSTTRGMTRAMT--MPPVSPVGAEG 2365
Query: 327 EIKLKSE 333
+ L+S+
Sbjct: 2366 PVVLRSK 2372
>gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens]
Length = 359
Score = 37.4 bits (85), Expect = 0.15
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 22/138 (15%)
Query: 157 EEVDKDEDAASLGSQKGGIT--------KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLG 208
E DKD++A S G+Q I K G+L K + S +++R+ L
Sbjct: 91 ERYDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKDH--SFLGFEWQKRWCAL---- 144
Query: 209 DGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRR-----FAFELKMQDKSSYLLAA 263
S + +Y K+ KG +D V NN +R+ FE+ DK Y A
Sbjct: 145 --SKTVFYYYGSDKDKQQKGEFAIDG-YSVRMNNTLRKDGKKDCCFEISAPDKRIYQFTA 201
Query: 264 DSEVEMEEWITILNKILQ 281
S + EEW+ L +LQ
Sbjct: 202 ASPKDAEEWVQQLKFVLQ 219
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,728,354
Number of Sequences: 37866
Number of extensions: 3276569
Number of successful extensions: 8853
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 8488
Number of HSP's gapped (non-prelim): 343
length of query: 2069
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1951
effective length of database: 13,779,330
effective search space: 26883472830
effective search space used: 26883472830
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.