Search of human proteins with 239755252

Search of human proteins with 239755252

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239755252 PREDICTED: hypothetical protein [Homo sapiens]
         (377 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755252 PREDICTED: hypothetical protein [Homo sapiens]           785   0.0  
gi|169201936 PREDICTED: hypothetical protein [Homo sapiens]           785   0.0  
gi|169191966 PREDICTED: hypothetical protein [Homo sapiens]           785   0.0  
gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Ho...    68   2e-11
gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Ho...    68   2e-11
gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Ho...    67   2e-11
gi|119220585 apical early endosomal glycoprotein precursor [Homo...    64   2e-10
gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens]          54   2e-07
gi|38158013 MAM domain containing 1 isoform 2 [Homo sapiens]           54   2e-07
gi|223278413 MAM domain containing 2 [Homo sapiens]                    53   5e-07
gi|24111244 MAM domain containing glycosylphosphatidylinositol a...    51   2e-06
gi|182508169 neuropilin 1 isoform a [Homo sapiens]                     44   2e-04
gi|223942069 enterokinase precursor [Homo sapiens]                     38   0.017
gi|14043022 methionyl-tRNA synthetase [Homo sapiens]                   31   2.1  
gi|153070264 meprin A beta [Homo sapiens]                              30   2.7  
gi|52426743 cisplatin resistance-associated overexpressed protei...    29   7.9  
gi|19923485 cisplatin resistance-associated overexpressed protei...    29   7.9  
gi|115583683 hypothetical protein LOC253714 [Homo sapiens]             29   7.9  

>gi|239755252 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 377

 Score =  785 bits (2026), Expect = 0.0
 Identities = 377/377 (100%), Positives = 377/377 (100%)

Query: 1   MAVIYIVTDFITADSFRLECGCVAYGVKSLLDLGSPRERVRNVFIVIENTKLSSNTDSMM 60
           MAVIYIVTDFITADSFRLECGCVAYGVKSLLDLGSPRERVRNVFIVIENTKLSSNTDSMM
Sbjct: 1   MAVIYIVTDFITADSFRLECGCVAYGVKSLLDLGSPRERVRNVFIVIENTKLSSNTDSMM 60

Query: 61  RRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVD 120
           RRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVD
Sbjct: 61  RRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVD 120

Query: 121 SISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQ 180
           SISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQ
Sbjct: 121 SISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQ 180

Query: 181 WERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAE 240
           WERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAE
Sbjct: 181 WERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAE 240

Query: 241 RELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFEST 300
           RELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFEST
Sbjct: 241 RELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFEST 300

Query: 301 PQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRV 360
           PQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRV
Sbjct: 301 PQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRV 360

Query: 361 RLYNNKVRRKLHLFQIH 377
           RLYNNKVRRKLHLFQIH
Sbjct: 361 RLYNNKVRRKLHLFQIH 377


>gi|169201936 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 377

 Score =  785 bits (2026), Expect = 0.0
 Identities = 377/377 (100%), Positives = 377/377 (100%)

Query: 1   MAVIYIVTDFITADSFRLECGCVAYGVKSLLDLGSPRERVRNVFIVIENTKLSSNTDSMM 60
           MAVIYIVTDFITADSFRLECGCVAYGVKSLLDLGSPRERVRNVFIVIENTKLSSNTDSMM
Sbjct: 1   MAVIYIVTDFITADSFRLECGCVAYGVKSLLDLGSPRERVRNVFIVIENTKLSSNTDSMM 60

Query: 61  RRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVD 120
           RRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVD
Sbjct: 61  RRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVD 120

Query: 121 SISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQ 180
           SISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQ
Sbjct: 121 SISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQ 180

Query: 181 WERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAE 240
           WERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAE
Sbjct: 181 WERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAE 240

Query: 241 RELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFEST 300
           RELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFEST
Sbjct: 241 RELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFEST 300

Query: 301 PQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRV 360
           PQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRV
Sbjct: 301 PQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRV 360

Query: 361 RLYNNKVRRKLHLFQIH 377
           RLYNNKVRRKLHLFQIH
Sbjct: 361 RLYNNKVRRKLHLFQIH 377


>gi|169191966 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 377

 Score =  785 bits (2026), Expect = 0.0
 Identities = 377/377 (100%), Positives = 377/377 (100%)

Query: 1   MAVIYIVTDFITADSFRLECGCVAYGVKSLLDLGSPRERVRNVFIVIENTKLSSNTDSMM 60
           MAVIYIVTDFITADSFRLECGCVAYGVKSLLDLGSPRERVRNVFIVIENTKLSSNTDSMM
Sbjct: 1   MAVIYIVTDFITADSFRLECGCVAYGVKSLLDLGSPRERVRNVFIVIENTKLSSNTDSMM 60

Query: 61  RRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVD 120
           RRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVD
Sbjct: 61  RRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVD 120

Query: 121 SISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQ 180
           SISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQ
Sbjct: 121 SISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQ 180

Query: 181 WERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAE 240
           WERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAE
Sbjct: 181 WERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAE 240

Query: 241 RELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFEST 300
           RELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFEST
Sbjct: 241 RELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFEST 300

Query: 301 PQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRV 360
           PQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRV
Sbjct: 301 PQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRV 360

Query: 361 RLYNNKVRRKLHLFQIH 377
           RLYNNKVRRKLHLFQIH
Sbjct: 361 RLYNNKVRRKLHLFQIH 377


>gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Homo
            sapiens]
          Length = 1817

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 57/195 (29%), Positives = 84/195 (43%), Gaps = 19/195 (9%)

Query: 170  LWQNTAALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDG 229
            LW  T     QW+R  + +      Q+VF  +   +Y  D  +A+DDISF   C P    
Sbjct: 844  LWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGD--VAVDDISFQD-CSPLLSP 900

Query: 230  ILLCQE-ALNAERELCHPDTDLCRF-----DATDEELRLCQA----CGFEFDMCEWTSEA 279
               C +       + C     LC F     D +DE   +C+     C FEFD+C W  E 
Sbjct: 901  ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEK 960

Query: 280  SAGQISWMRTKAREIPAFESTPQQDQG-GDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVC 338
                  W   KA  IPA  + P  D   G+  G+Y+++  K  F    + + A ++S V 
Sbjct: 961  DE-DFDW-NLKASSIPAAGTEPAADHTLGNSSGHYIFI--KSLFPQQPMRA-ARISSPVI 1015

Query: 339  HCLGKSCHLQFYYAM 353
                K+C + F+Y M
Sbjct: 1016 SKRSKNCKIIFHYHM 1030



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 65/235 (27%), Positives = 98/235 (41%), Gaps = 26/235 (11%)

Query: 63  CLNYERCDFEDGLCHMTQDQSLQPSWTKRSG---MIGLSPPFYDHNGDVSAHFLSLVSRV 119
           C    +C+FE G+C+  QD      WT+  G    +   P   +  G    H+L + S  
Sbjct: 499 CAPELQCNFETGICNWEQDAKDDFDWTRNQGPTPTLNTGPMKDNTLGTAKGHYLYIESSE 558

Query: 120 DSI---SSSLRSRVFLPTNDQHDCQITFYY--FSCQVSGKLMVGLQTACGGPIQHLWQNT 174
                 S++L S + L   D   C   FYY  F  ++  +L +  +       Q LWQ  
Sbjct: 559 PQAFQDSAALLSPI-LNATDTKGCTFRFYYHMFGKRIY-RLAIYQRIWSDSRGQLLWQIF 616

Query: 175 AALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSS-----GCLPANDG 229
               N+W R  + I S Q FQ++ E  +   +  D  IAIDD+SF       G LPA+  
Sbjct: 617 GNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGD--IAIDDLSFMDCTLYPGNLPAD-- 672

Query: 230 ILLCQEALNAEREL----CHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEAS 280
            L      +    L    C  +  +CR D     +   Q C F++D  + + EAS
Sbjct: 673 -LPTPPETSVPVTLPPHNCTDNEFICRSDG--HCIEKMQKCDFKYDCPDKSDEAS 724



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 62/249 (24%), Positives = 95/249 (38%), Gaps = 42/249 (16%)

Query: 68   RCDFEDGLCHMTQDQSLQPSWTKRSGMIGL--SPPFYDHN-GDVSAHFLSLVS------- 117
            RCDFE  LC   Q++     W  ++  I    + P  DH  G+ S H++ + S       
Sbjct: 946  RCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPM 1005

Query: 118  RVDSISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAAL 177
            R   ISS + S+         +C+I F+Y         +  +Q +     + L   T   
Sbjct: 1006 RAARISSPVISK------RSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQ 1059

Query: 178  PNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEAL 237
             N W R  + +   + FQ+ FEG++      D  IA+DDI  +  CL  +D +   QE L
Sbjct: 1060 GNFWRREELSLFGDEDFQLKFEGRVGKGQRGD--IALDDIVLTENCLSLHDSV---QEEL 1114

Query: 238  --------------NAERELCHPDTDLCRF-----DATDEELRLCQACGFEFDMCEWTSE 278
                                C+     C F     D T E  +   +C FE   C W   
Sbjct: 1115 AVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTGEN-KCGSSCTFEKGWCGW-QN 1172

Query: 279  ASAGQISWM 287
            + A    W+
Sbjct: 1173 SQADNFDWV 1181



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 67/311 (21%), Positives = 116/311 (37%), Gaps = 44/311 (14%)

Query: 53  SSNTDSMMRRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSP--PFYDHNGDVS- 109
           S  +D     C  +  CDFE G C      +    W    G+       P  DH  +++ 
Sbjct: 100 SDESDEDPATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINH 159

Query: 110 AHFLSLVSRVDSISSSLRSRVFLPT-NDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQ 168
             F+ L ++     + L S V          CQ+ F+Y   Q S  L V  +T+  G +Q
Sbjct: 160 GSFIYLEAQRSPGVAKLGSPVLTKLLTASTPCQVQFWYHLSQHSN-LSVFTRTSLDGNLQ 218

Query: 169 HLWQNTAALPNQWERNVIKI-----QSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGC 223
              +      +QW    I +     +S+  FQ++ E  + S+   +  +A+DDIS S  C
Sbjct: 219 KQGKIIRFSESQWSHAKIDLIAEAGESTLPFQLILEATVLSS---NATVALDDISVSQEC 275

Query: 224 LPANDGILLCQEALNAERELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQ 283
                                  +        T  + +  + C FE + C+W    S   
Sbjct: 276 -----------------------EISYKSLPRTSTQSKFSK-CDFEANSCDWFEAISGDH 311

Query: 284 ISWMRTKAREIPA---FESTPQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHC 340
             W+R+   E+ A    ++ P+       +G+++++  K     + L   A L S     
Sbjct: 312 FDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKS----SSLWQVAKLQSPTFSQ 367

Query: 341 LGKSCHLQFYY 351
            G  C L F++
Sbjct: 368 TGPGCILSFWF 378



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 43/166 (25%), Positives = 64/166 (38%), Gaps = 13/166 (7%)

Query: 69   CDFEDG------LCHMTQDQSLQPSWTKRSGMIGLSP-PFYDHNGDVSAHFL---SLVSR 118
            C+FE         C +TQD      W   S +   +  P  DH      HFL   S  S+
Sbjct: 1439 CNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSK 1498

Query: 119  VDSISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALP 178
              S++    S+ F  +      +  FY    +  G L V      G  I  +W       
Sbjct: 1499 EGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNIL-VWSVIGNKR 1557

Query: 179  NQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCL 224
              W    + + S+  F+V FE  +     +D  IA+DDISF+  C+
Sbjct: 1558 TGWTYGSVPLSSNSPFKVAFEADLDGN--EDIFIALDDISFTPECV 1601


>gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Homo
            sapiens]
          Length = 1817

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 57/195 (29%), Positives = 84/195 (43%), Gaps = 19/195 (9%)

Query: 170  LWQNTAALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDG 229
            LW  T     QW+R  + +      Q+VF  +   +Y  D  +A+DDISF   C P    
Sbjct: 844  LWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGD--VAVDDISFQD-CSPLLSP 900

Query: 230  ILLCQE-ALNAERELCHPDTDLCRF-----DATDEELRLCQA----CGFEFDMCEWTSEA 279
               C +       + C     LC F     D +DE   +C+     C FEFD+C W  E 
Sbjct: 901  ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEK 960

Query: 280  SAGQISWMRTKAREIPAFESTPQQDQG-GDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVC 338
                  W   KA  IPA  + P  D   G+  G+Y+++  K  F    + + A ++S V 
Sbjct: 961  DE-DFDW-NLKASSIPAAGTEPAADHTLGNSSGHYIFI--KSLFPQQPMRA-ARISSPVI 1015

Query: 339  HCLGKSCHLQFYYAM 353
                K+C + F+Y M
Sbjct: 1016 SKRSKNCKIIFHYHM 1030



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 65/235 (27%), Positives = 98/235 (41%), Gaps = 26/235 (11%)

Query: 63  CLNYERCDFEDGLCHMTQDQSLQPSWTKRSG---MIGLSPPFYDHNGDVSAHFLSLVSRV 119
           C    +C+FE G+C+  QD      WT+  G    +   P   +  G    H+L + S  
Sbjct: 499 CAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSE 558

Query: 120 DSI---SSSLRSRVFLPTNDQHDCQITFYY--FSCQVSGKLMVGLQTACGGPIQHLWQNT 174
                 S++L S + L   D   C   FYY  F  ++  +L +  +       Q LWQ  
Sbjct: 559 PQAFQDSAALLSPI-LNATDTKGCTFRFYYHMFGKRIY-RLAIYQRIWSDSRGQLLWQIF 616

Query: 175 AALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSS-----GCLPANDG 229
               N+W R  + I S Q FQ++ E  +   +  D  IAIDD+SF       G LPA+  
Sbjct: 617 GNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGD--IAIDDLSFMDCTLYPGNLPAD-- 672

Query: 230 ILLCQEALNAEREL----CHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEAS 280
            L      +    L    C  +  +CR D     +   Q C F++D  + + EAS
Sbjct: 673 -LPTPPETSVPVTLPPHNCTDNEFICRSDG--HCIEKMQKCDFKYDCPDKSDEAS 724



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 63/249 (25%), Positives = 95/249 (38%), Gaps = 42/249 (16%)

Query: 68   RCDFEDGLCHMTQDQSLQPSWTKRSGMIGL--SPPFYDHN-GDVSAHFLSLVS------- 117
            RCDFE  LC   Q++     W  ++  I    + P  DH  G+ S H++ + S       
Sbjct: 946  RCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPM 1005

Query: 118  RVDSISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAAL 177
            R   ISS + S+         +C+I F+Y         +  +Q +     + L   T   
Sbjct: 1006 RAARISSPVISK------RSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQ 1059

Query: 178  PNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEAL 237
             N W R  + +   + FQ+ FEG++      D  IA+DDI  +  CL  +D +   QE L
Sbjct: 1060 GNFWRREELSLFGDEDFQLKFEGRVGKGQRGD--IALDDIVLTENCLSLHDSV---QEEL 1114

Query: 238  --------------NAERELCHPDTDLCRF-----DATDEELRLCQACGFEFDMCEWTSE 278
                                C+     C F     D TDE      +C FE   C W   
Sbjct: 1115 AVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDEN-ECGSSCTFEKGWCGW-QN 1172

Query: 279  ASAGQISWM 287
            + A    W+
Sbjct: 1173 SQADNFDWV 1181



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 67/311 (21%), Positives = 116/311 (37%), Gaps = 44/311 (14%)

Query: 53  SSNTDSMMRRCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSP--PFYDHNGDVS- 109
           S  +D     C  +  CDFE G C      +    W    G+       P  DH  +++ 
Sbjct: 100 SDESDEDPATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINH 159

Query: 110 AHFLSLVSRVDSISSSLRSRVFLPT-NDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQ 168
             F+ L ++     + L S V          CQ+ F+Y   Q S  L V  +T+  G +Q
Sbjct: 160 GSFIYLEAQRSPGVAKLGSPVLTKLLTASTPCQVQFWYHLSQHSN-LSVFTRTSLDGNLQ 218

Query: 169 HLWQNTAALPNQWERNVIKI-----QSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGC 223
              +      +QW    I +     +S+  FQ++ E  + S+   +  +A+DDIS S  C
Sbjct: 219 KQGKIIRFSESQWSHAKIDLIAEAGESTLPFQLILEATVLSS---NATVALDDISVSQEC 275

Query: 224 LPANDGILLCQEALNAERELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQ 283
                                  +        T  + +  + C FE + C+W    S   
Sbjct: 276 -----------------------EISYKSLPRTSTQSKFSK-CDFEANSCDWFEAISGDH 311

Query: 284 ISWMRTKAREIPA---FESTPQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHC 340
             W+R+   E+ A    ++ P+       +G+++++  K     + L   A L S     
Sbjct: 312 FDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKS----SSLWQVAKLQSPTFSQ 367

Query: 341 LGKSCHLQFYY 351
            G  C L F++
Sbjct: 368 TGPGCILSFWF 378



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 43/166 (25%), Positives = 64/166 (38%), Gaps = 13/166 (7%)

Query: 69   CDFEDG------LCHMTQDQSLQPSWTKRSGMIGLSP-PFYDHNGDVSAHFL---SLVSR 118
            C+FE         C +TQD      W   S +   +  P  DH      HFL   S  S+
Sbjct: 1439 CNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSK 1498

Query: 119  VDSISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALP 178
              S++    S+ F  +      +  FY    +  G L V      G  I  +W       
Sbjct: 1499 EGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNIL-VWSVIGNKR 1557

Query: 179  NQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCL 224
              W    + + S+  F+V FE  +     +D  IA+DDISF+  C+
Sbjct: 1558 TGWTYGSVPLSSNSPFKVAFEADLDGN--EDIFIALDDISFTPECV 1601


>gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Homo
           sapiens]
          Length = 1542

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 56/195 (28%), Positives = 84/195 (43%), Gaps = 19/195 (9%)

Query: 170 LWQNTAALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDG 229
           LW  T     QW+R  + +      Q+VF  +   +Y  D  +A+DDISF   C P    
Sbjct: 569 LWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGD--VAVDDISFQD-CSPLLSP 625

Query: 230 ILLCQE-ALNAERELCHPDTDLCRF-----DATDEELRLCQA----CGFEFDMCEWTSEA 279
              C +       + C     LC F     D +DE   +C+     C FEFD+C W  E 
Sbjct: 626 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEK 685

Query: 280 SAGQISWMRTKAREIPAFESTPQQDQG-GDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVC 338
                 W   KA  IPA  + P  D   G+  G+Y+++ +   F    + + A ++S V 
Sbjct: 686 DE-DFDW-NLKASSIPAAGTEPAADHTLGNSSGHYIFINSL--FPQQPMRA-ARISSPVI 740

Query: 339 HCLGKSCHLQFYYAM 353
               K+C + F+Y M
Sbjct: 741 SKRSKNCKIIFHYHM 755



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 65/235 (27%), Positives = 98/235 (41%), Gaps = 26/235 (11%)

Query: 63  CLNYERCDFEDGLCHMTQDQSLQPSWTKRSG---MIGLSPPFYDHNGDVSAHFLSLVSRV 119
           C    +C+FE G+C+  QD      WT+  G    +   P   +  G    H+L + S  
Sbjct: 224 CAPELQCNFETGICNWEQDAKDDFDWTRNQGPTPTLNTGPMKDNTLGTAKGHYLYIESSE 283

Query: 120 DSI---SSSLRSRVFLPTNDQHDCQITFYY--FSCQVSGKLMVGLQTACGGPIQHLWQNT 174
                 S++L S + L   D   C   FYY  F  ++  +L +  +       Q LWQ  
Sbjct: 284 PQAFQDSAALLSPI-LNATDTKGCTFRFYYHMFGKRIY-RLAIYQRIWSDSRGQLLWQIF 341

Query: 175 AALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSS-----GCLPANDG 229
               N+W R  + I S Q FQ++ E  +   +  D  IAIDD+SF       G LPA+  
Sbjct: 342 GNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGD--IAIDDLSFMDCTLYPGNLPAD-- 397

Query: 230 ILLCQEALNAEREL----CHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEAS 280
            L      +    L    C  +  +CR D     +   Q C F++D  + + EAS
Sbjct: 398 -LPTPPETSVPVTLPPHNCTDNEFICRSDG--HCIEKMQKCDFKYDCPDKSDEAS 449



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 62/249 (24%), Positives = 95/249 (38%), Gaps = 42/249 (16%)

Query: 68  RCDFEDGLCHMTQDQSLQPSWTKRSGMIGL--SPPFYDHN-GDVSAHFLSLVS------- 117
           RCDFE  LC   Q++     W  ++  I    + P  DH  G+ S H++ + S       
Sbjct: 671 RCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFINSLFPQQPM 730

Query: 118 RVDSISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAAL 177
           R   ISS + S+         +C+I F+Y         +  +Q +     + L   T   
Sbjct: 731 RAARISSPVISK------RSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQ 784

Query: 178 PNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEAL 237
            N W R  + +   + FQ+ FEG++      D  IA+DDI  +  CL  +D +   QE L
Sbjct: 785 GNFWRREELSLFGDEDFQLKFEGRVGKGQRGD--IALDDIVLTENCLSLHDSV---QEEL 839

Query: 238 --------------NAERELCHPDTDLCRF-----DATDEELRLCQACGFEFDMCEWTSE 278
                               C+     C F     D T E  +   +C FE   C W   
Sbjct: 840 AVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTGEN-KCGSSCTFEKGWCGW-QN 897

Query: 279 ASAGQISWM 287
           + A    W+
Sbjct: 898 SQADNFDWV 906



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 43/166 (25%), Positives = 64/166 (38%), Gaps = 13/166 (7%)

Query: 69   CDFEDG------LCHMTQDQSLQPSWTKRSGMIGLSP-PFYDHNGDVSAHFL---SLVSR 118
            C+FE         C +TQD      W   S +   +  P  DH      HFL   S  S+
Sbjct: 1164 CNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSK 1223

Query: 119  VDSISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALP 178
              S++    S+ F  +      +  FY    +  G L V      G  I  +W       
Sbjct: 1224 EGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNIL-VWSVIGNKR 1282

Query: 179  NQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCL 224
              W    + + S+  F+V FE  +     +D  IA+DDISF+  C+
Sbjct: 1283 TGWTYGSVPLSSNSPFKVAFEADLDGN--EDIFIALDDISFTPECV 1326



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 21/89 (23%), Positives = 38/89 (42%), Gaps = 7/89 (7%)

Query: 266 CGFEFDMCEWTSEASAGQISWMRTKAREIPA---FESTPQQDQGGDDEGYYVWVGAKHGF 322
           C FE + C+W    S     W+R+   E+ A    ++ P+       +G+++++  K   
Sbjct: 19  CDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKS-- 76

Query: 323 TLNHLDSRAYLNSSVCHCLGKSCHLQFYY 351
             + L   A L S      G  C L F++
Sbjct: 77  --SSLWQVAKLQSPTFSQTGPGCILSFWF 103


>gi|119220585 apical early endosomal glycoprotein precursor [Homo
           sapiens]
          Length = 1137

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 77/327 (23%), Positives = 126/327 (38%), Gaps = 55/327 (16%)

Query: 63  CLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFY---DHNGDVSAHFLSLVSRV 119
           C  +   DFE GL    + +     W++     G   P +   DH+ + SA    LVS  
Sbjct: 265 CGRHIATDFETGLGPWNRSEG----WSRNHRAGGPERPSWPRRDHSRN-SAQGSFLVSVA 319

Query: 120 DSISSSLRSRVFLPTNDQHDCQITFY-YFSCQVSGKLMVGLQTACGGPIQH---LWQNTA 175
           +  + ++ S      +   +C + FY Y S   +G L + LQT   G  +    L +   
Sbjct: 320 EPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRG 379

Query: 176 ALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILL--- 232
            L   W R+ + IQS+  FQ++  GQ         V+ +DD+  S  C P ++   L   
Sbjct: 380 ELGTAWVRDRVDIQSAYPFQILLAGQTG----PGGVVGLDDLILSDHCRPVSEVSTLQPL 435

Query: 233 ---------------------CQEALNAERELCHPDTDLCRFD---ATDEELRLCQACGF 268
                                C++   A  +LC P   LC F+   A  E+ + C    F
Sbjct: 436 PPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQCAGGEDEQACGTTDF 495

Query: 269 EFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQGGDDEGYYVWVGAKHGFTLNHLD 328
           E        +AS G++ W R  A+E         Q       G+++ +    G     L 
Sbjct: 496 ESPEAGGWEDASVGRLQWRRVSAQE--------SQGSSAAAAGHFLSLQRAWG----QLG 543

Query: 329 SRAYLNSSVCHCLGKSCHLQFYYAMES 355
           + A + + +    G SC L   Y ++S
Sbjct: 544 AEARVLTPLLGPSGPSCELHLAYYLQS 570



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 36/130 (27%), Positives = 50/130 (38%), Gaps = 6/130 (4%)

Query: 247 DTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQG 306
           D   C +      L    AC FE D C W   +++G  SW+R +A               
Sbjct: 47  DEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSG-YSWLRDRAGAALEGPGPHSDHTL 105

Query: 307 GDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQ-FYYAMESSVLRVRLYNN 365
           G D G+Y+ VG   G       S A L S        SC L+ +Y+A    V  +R+   
Sbjct: 106 GTDLGWYMAVGTHRGKEA----STAALRSPTLREAASSCKLRLWYHAASGDVAELRVELT 161

Query: 366 KVRRKLHLFQ 375
                L L+Q
Sbjct: 162 HGAETLTLWQ 171



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 43/166 (25%), Positives = 65/166 (39%), Gaps = 17/166 (10%)

Query: 69   CDFEDGLC---HMTQDQSLQPSWTKRSGMIGL---SPPFYDHNGDVSAHFLSLVSRV--- 119
            CDFE GLC   H+        SW    G        PP     G  + HF    + V   
Sbjct: 894  CDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGP 953

Query: 120  DSISSSLRSRVFLPTNDQHDCQITFYYFSCQ---VSGKLMVGLQTACGGPIQHLWQNTAA 176
               ++ LRS     T     C   +Y+         G+L V L +A G     +W     
Sbjct: 954  GGRAAWLRSEPLPAT--PASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLA--VWGAGGH 1009

Query: 177  LPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSG 222
              +QW    +++ S++ FQ+VFE  +         IA+DD+ + +G
Sbjct: 1010 RRHQWLEAQVEVASAKEFQIVFEATLGGQPALGP-IALDDVEYLAG 1054


>gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens]
          Length = 956

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 51/173 (29%), Positives = 76/173 (43%), Gaps = 22/173 (12%)

Query: 69  CDFEDG-LCHMTQDQSLQPSWTKRSGMIGLSP------PFYDHNGDVSAHFLSLVS---R 118
           C FEDG +C  TQD +    WTK+S     +       P  D +G     ++ + +   R
Sbjct: 748 CGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRPR 807

Query: 119 VDSISSSLRSRVFL--------PTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQH- 169
           ++   + L S VF         PTN  + C   FY+   Q  G L V L+      I++ 
Sbjct: 808 LEGEKARLLSPVFSIAPKNPYGPTNTAY-CFSFFYHMYGQHIGVLNVYLRLKGQTTIENP 866

Query: 170 LWQNTAALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSG 222
           LW ++     +W    + I     FQ++FEG      E D  IAIDD+S + G
Sbjct: 867 LWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGD--IAIDDVSIAEG 917


>gi|38158013 MAM domain containing 1 isoform 2 [Homo sapiens]
          Length = 727

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 51/173 (29%), Positives = 76/173 (43%), Gaps = 22/173 (12%)

Query: 69  CDFEDG-LCHMTQDQSLQPSWTKRSGMIGLSP------PFYDHNGDVSAHFLSLVS---R 118
           C FEDG +C  TQD +    WTK+S     +       P  D +G     ++ + +   R
Sbjct: 519 CGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRPR 578

Query: 119 VDSISSSLRSRVFL--------PTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQH- 169
           ++   + L S VF         PTN  + C   FY+   Q  G L V L+      I++ 
Sbjct: 579 LEGEKARLLSPVFSIAPKNPYGPTNTAY-CFSFFYHMYGQHIGVLNVYLRLKGQTTIENP 637

Query: 170 LWQNTAALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSG 222
           LW ++     +W    + I     FQ++FEG      E D  IAIDD+S + G
Sbjct: 638 LWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGD--IAIDDVSIAEG 688


>gi|223278413 MAM domain containing 2 [Homo sapiens]
          Length = 686

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 43/157 (27%), Positives = 66/157 (42%), Gaps = 6/157 (3%)

Query: 69  CDFEDGLCHMTQDQSLQPSWTKRSGMIGLS--PPFYDHNGDVSAH-FLSLVSRVDSISSS 125
           C FE   C  TQ++  + SW +R G    S   P  DH   V  + ++     V    + 
Sbjct: 509 CTFEQDECTFTQEKRNRSSWHRRRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKAR 568

Query: 126 LRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQWERNV 185
           L SR     + +H C   FY+     +G L V L+         LW+        W R +
Sbjct: 569 LLSRPLRGVSGKH-CLTFFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRGEQSISWLRAL 627

Query: 186 IKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSG 222
           I+    ++ Q++FE     +   D  IAIDD+ F +G
Sbjct: 628 IEYSCERQHQIIFEAIRGVSIRSD--IAIDDVKFQAG 662



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 64/292 (21%), Positives = 114/292 (39%), Gaps = 51/292 (17%)

Query: 69  CDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFY---DHNGDVSAHFLSLVSRVDSISSS 125
           C+FE  LC+  QD+   P WT+    + + P  Y   DH   +  + L+  +   +    
Sbjct: 342 CNFEQDLCNFYQDKE-GPGWTR----VKVKPNMYRAGDHTTGLGYYLLA--NTKFTSQPG 394

Query: 126 LRSRVF---LPTNDQHDCQITF-YYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQW 181
              R++   LP N Q+  +  +  Y   ++S  L V +        + +W    +    W
Sbjct: 395 YIGRLYGPSLPGNLQYCLRFHYAIYGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVW 454

Query: 182 ERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAER 241
            +  I  +     +VVF   +  ++    ++A+DDI+   G             + ++  
Sbjct: 455 MQAEITFKKPMPTKVVFM-SLCKSFWDCGLVALDDITIQLG-------------SCSSSE 500

Query: 242 ELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFESTP 301
           +L  P  +                C FE D C +T E    + SW R +  E P   + P
Sbjct: 501 KLPPPPGE----------------CTFEQDECTFTQE-KRNRSSWHRRRG-ETPTSYTGP 542

Query: 302 QQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAM 353
           + D      GYY+++ A H   + +      L+  +    GK C L F+Y M
Sbjct: 543 KGDH-TTGVGYYMYIEASH---MVYGQKARLLSRPLRGVSGKHC-LTFFYHM 589



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 57/264 (21%), Positives = 93/264 (35%), Gaps = 58/264 (21%)

Query: 69  CDFEDG-LCHMTQDQSLQPSWTKRSGMI----GLSPPFYDHNGDVSAHFLSLVSRVDSIS 123
           CDFE+  LC      +   +W    G I     + P  +    ++  H++     VDS+ 
Sbjct: 170 CDFEENHLCGFVNRWNPNVNWFVGGGSIRNVHSILPQDHTFKSELG-HYMY----VDSVY 224

Query: 124 SSLRSRVF-----LPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALP 178
                 V      L T     C ++FYY   Q +  +         G  + +W+      
Sbjct: 225 VKHFQEVAQLISPLTTAPMAGC-LSFYYQIQQGNDNVFSLYTRDVAGLYEEIWKADRPGN 283

Query: 179 NQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALN 238
             W    ++  +    +V+FE  +A    +   +A+DDISFS    P +           
Sbjct: 284 AAWNLAEVEFSAPYPMEVIFE--VAFNGPKGGYVALDDISFS----PVH----------- 326

Query: 239 AERELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFE 298
                C   T+L  F A +       +C FE D+C +  +       W R K +      
Sbjct: 327 -----CQNQTELL-FSAVE------ASCNFEQDLCNFYQDKEGP--GWTRVKVK------ 366

Query: 299 STPQQDQGGDDE---GYYVWVGAK 319
             P   + GD     GYY+    K
Sbjct: 367 --PNMYRAGDHTTGLGYYLLANTK 388


>gi|24111244 MAM domain containing glycosylphosphatidylinositol
           anchor 1 [Homo sapiens]
          Length = 955

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 60/234 (25%), Positives = 97/234 (41%), Gaps = 35/234 (14%)

Query: 5   YIVTDFITADSFRLECGCVAYGVKSLLDLGSPRERVRNVFIVIENTKLSSNTDSMMRRCL 64
           YI+TD     S+  E     Y      D+ S   R+ +    I +  LS NT        
Sbjct: 706 YILTDLRVPHSY--EVRLTPYTTFGAGDMAS---RIIHYTEPINSPNLSDNT-------- 752

Query: 65  NYERCDFEDG-LCHMTQDQSLQPSWTKRSGMI-------GLSPPFYDHNGDVSAHFLSL- 115
               C FED  +C  TQD +    WT+++ +           PP  D +G    +++ + 
Sbjct: 753 ----CHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPT-DISGTPEGYYMFIE 807

Query: 116 VSRVDSISSSLRSRVFLP---TNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQ-HLW 171
            SR   +    R+R+  P    + +  C   FY+   +  G L + +++   G +  H W
Sbjct: 808 TSRPRELGD--RARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGALDTHAW 865

Query: 172 QNTAALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLP 225
             +    N W++  + I  S  FQ++FEG     Y  D  IAIDD++   G  P
Sbjct: 866 SLSGNKGNVWQQAHVPISPSGPFQIIFEGVRGPGYLGD--IAIDDVTLKKGECP 917


>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
          Length = 923

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 12/159 (7%)

Query: 69  CDFEDG----LCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVDSISS 124
           C+F  G     CH   D  +Q  W+  +   G   P  DH GD +  +           +
Sbjct: 650 CEFGWGSHKTFCHWEHDNHVQLKWSVLTSKTG---PIQDHTGDGNFIYSQADENQKGKVA 706

Query: 125 SLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHL-WQNTAALPNQW-E 182
            L S V    N  H C   +Y+ S    G L V L+         L W       + W E
Sbjct: 707 RLVSPVVYSQNSAH-CMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKE 765

Query: 183 RNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSS 221
             V+  +S + +QV+FEG++         IA+DDIS ++
Sbjct: 766 GRVLLHKSLKLYQVIFEGEIGKGNLGG--IAVDDISINN 802


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 41/171 (23%), Positives = 69/171 (40%), Gaps = 24/171 (14%)

Query: 65  NYER--CDFEDGLCHMTQDQSLQPSWTKRSGMIGLSP---PFYDHN-GDVSAHFLSLVS- 117
           NYE+  C+FEDG C   QD +    W +  G    SP   P +DH  G+ S  ++S  + 
Sbjct: 341 NYEKINCNFEDGFCFWVQDLNDDNEWERIQGST-FSPFTGPNFDHTFGNASGFYISTPTG 399

Query: 118 ------RVDSISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLW 171
                 RV  +S  L   +      +  C   +Y+   +   KL + +        + ++
Sbjct: 400 PGGRQERVGLLSLPLDPTL------EPACLSFWYHMYGENVHKLSINISND-QNMEKTVF 452

Query: 172 QNTAALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSG 222
           Q      + W    + +  + +F+V F             IA+DDIS + G
Sbjct: 453 QKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSD---IALDDISLTYG 500


>gi|14043022 methionyl-tRNA synthetase [Homo sapiens]
          Length = 900

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 20/115 (17%)

Query: 233 CQEALNAERELCHPDTDLCR------------FDATDEELRLCQACGFEFDMCEWTSEAS 280
           C + +NA  EL  P   +CR             D    E RL +  G      +WT  A 
Sbjct: 421 CGKLINAV-ELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQ 479

Query: 281 AGQISWMRT--KAREIPAFES--TPQQDQGGDDEGYYVWVGAKHGF---TLNHLD 328
               SW+R   K R I       TP   +G +D+ +YVW  A  G+   T N+ D
Sbjct: 480 FITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTD 534


>gi|153070264 meprin A beta [Homo sapiens]
          Length = 701

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 39/170 (22%), Positives = 66/170 (38%), Gaps = 15/170 (8%)

Query: 67  ERCDFE-DGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVDSISSS 125
           + C FE + +C M Q       W + S +     P  DH+              DS S +
Sbjct: 263 DSCSFELENVCGMIQSSGDNADWQRVSQVP--RGPESDHSNMGQCQGSGFFMHFDSSSVN 320

Query: 126 ------LRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQH---LWQNTAA 176
                 L SR   P      C   + Y S   S +L + ++      +     L +    
Sbjct: 321 VGATAVLESRTLYPKRG-FQCLQFYLYNSGSESDQLNIYIREYSADNVDGNLTLVEEIKE 379

Query: 177 LPN-QWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLP 225
           +P   W+   + ++ +++F+VVFEG+  S       ++IDDI+ S    P
Sbjct: 380 IPTGSWQLYHVTLKVTKKFRVVFEGRKGSGASLGG-LSIDDINLSETRCP 428


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 220 SSGCLPANDGILLCQEALNAERELCHPDTDLCR-FDATDEELRLCQACG 267
           S G +    G++   E L  EREL    T     F A ++++ +C+ CG
Sbjct: 148 SEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCG 196


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 220 SSGCLPANDGILLCQEALNAERELCHPDTDLCR-FDATDEELRLCQACG 267
           S G +    G++   E L  EREL    T     F A ++++ +C+ CG
Sbjct: 148 SEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCG 196


>gi|115583683 hypothetical protein LOC253714 [Homo sapiens]
          Length = 1243

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 4/47 (8%)

Query: 146 YFSCQVS----GKLMVGLQTACGGPIQHLWQNTAALPNQWERNVIKI 188
           YFSC V     GK   G    C G ++ L  N   LP  +E + ++I
Sbjct: 28  YFSCAVDNRGGGKHFSGESYLCSGALKRLILNLDPLPTNFEEDTLEI 74


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.135    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,674,182
Number of Sequences: 37866
Number of extensions: 634484
Number of successful extensions: 1409
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1362
Number of HSP's gapped (non-prelim): 35
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.