Search of human proteins with 239741905

Search of human proteins with 239741905

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo
sapiens]
         (1710 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]    3363   0.0  
gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]    3334   0.0  
gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]    3289   0.0  
gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]             656   0.0  
gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]       600   e-171
gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5...   434   e-121
gi|148727311 hypothetical protein LOC389690 [Homo sapiens]            206   2e-52
gi|223278410 hypothetical protein LOC374977 [Homo sapiens]            172   3e-42
gi|149944578 HEAT repeat containing 7A isoform 2 [Homo sapiens]       162   3e-39
gi|149944469 HEAT repeat containing 7A isoform 2 [Homo sapiens]       162   3e-39
gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapi...   151   6e-36
gi|154937380 hypothetical protein LOC642475 [Homo sapiens]            122   3e-27
gi|187761381 maestro isoform d [Homo sapiens]                         100   2e-20
gi|187761375 maestro isoform a [Homo sapiens]                         100   2e-20
gi|47578111 hypothetical protein LOC140699 isoform 2 [Homo sapiens]    90   2e-17
gi|47578113 hypothetical protein LOC140699 isoform 3 [Homo sapiens]    69   4e-11
gi|187761379 maestro isoform c [Homo sapiens]                          55   8e-07
gi|187761377 maestro isoform b [Homo sapiens]                          55   8e-07
gi|117956387 hypothetical protein LOC80133 [Homo sapiens]              49   4e-05
gi|21071077 dishevelled-associated activator of morphogenesis 1 ...    35   0.48 
gi|57634534 nucleoporin 205kDa [Homo sapiens]                          35   0.63 
gi|22749269 ring finger protein 129 [Homo sapiens]                     34   1.1  
gi|100814339 coiled-coil domain containing 146 [Homo sapiens]          34   1.1  
gi|93102424 hypothetical protein LOC23116 [Homo sapiens]               34   1.4  
gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens]     33   3.1  
gi|12083581 phosphoinositide-specific phospholipase C beta 1 iso...    32   6.9  
gi|33356544 phosphoinositide-specific phospholipase C beta 1 iso...    32   6.9  
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ...    32   6.9  
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ...    32   6.9  
gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ...    32   6.9  

>gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1710

 Score = 3363 bits (8719), Expect = 0.0
 Identities = 1710/1710 (100%), Positives = 1710/1710 (100%)

Query: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVASSEEVSEERDDLGPLELHD 60
            MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVASSEEVSEERDDLGPLELHD
Sbjct: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVASSEEVSEERDDLGPLELHD 60

Query: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120
            SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV
Sbjct: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120

Query: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180
            PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL
Sbjct: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180

Query: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240
            VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR
Sbjct: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240

Query: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300
            LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH
Sbjct: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300

Query: 301  YNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEVLFVTQVLRQILEL 360
            YNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEVLFVTQVLRQILEL
Sbjct: 301  YNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEVLFVTQVLRQILEL 360

Query: 361  SVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKF 420
            SVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKF
Sbjct: 361  SVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKF 420

Query: 421  FFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILH 480
            FFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILH
Sbjct: 421  FFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILH 480

Query: 481  IIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDTVKI 540
            IIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDTVKI
Sbjct: 481  IIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDTVKI 540

Query: 541  ITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKSRQV 600
            ITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKSRQV
Sbjct: 541  ITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKSRQV 600

Query: 601  DLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRYLE 660
            DLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRYLE
Sbjct: 601  DLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRYLE 660

Query: 661  EHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRA 720
            EHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRA
Sbjct: 661  EHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRA 720

Query: 721  LGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEE 780
            LGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEE
Sbjct: 721  LGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEE 780

Query: 781  RIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHH 840
            RIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHH
Sbjct: 781  RIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHH 840

Query: 841  YVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVS 900
            YVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVS
Sbjct: 841  YVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVS 900

Query: 901  PVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANALSSL 960
            PVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANALSSL
Sbjct: 901  PVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANALSSL 960

Query: 961  EQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMWIYVHSTAVCIHL 1020
            EQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMWIYVHSTAVCIHL
Sbjct: 961  EQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMWIYVHSTAVCIHL 1020

Query: 1021 KLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKCKGD 1080
            KLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKCKGD
Sbjct: 1021 KLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKCKGD 1080

Query: 1081 LQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQ 1140
            LQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQ
Sbjct: 1081 LQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQ 1140

Query: 1141 MRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPME 1200
            MRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPME
Sbjct: 1141 MRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPME 1200

Query: 1201 SHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIH 1260
            SHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIH
Sbjct: 1201 SHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIH 1260

Query: 1261 LLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRV 1320
            LLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRV
Sbjct: 1261 LLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRV 1320

Query: 1321 TIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAE 1380
            TIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAE
Sbjct: 1321 TIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAE 1380

Query: 1381 LVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLEKGADQEEDEALR 1440
            LVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLEKGADQEEDEALR
Sbjct: 1381 LVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLEKGADQEEDEALR 1440

Query: 1441 VLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGD 1500
            VLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGD
Sbjct: 1441 VLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGD 1500

Query: 1501 VGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLH 1560
            VGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLH
Sbjct: 1501 VGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLH 1560

Query: 1561 SQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCSILTRKKPA 1620
            SQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCSILTRKKPA
Sbjct: 1561 SQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCSILTRKKPA 1620

Query: 1621 VLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPD 1680
            VLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPD
Sbjct: 1621 VLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPD 1680

Query: 1681 PGVRRAALETLTVLDSCSQHGFLASPQGMS 1710
            PGVRRAALETLTVLDSCSQHGFLASPQGMS
Sbjct: 1681 PGVRRAALETLTVLDSCSQHGFLASPQGMS 1710


>gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1706

 Score = 3334 bits (8645), Expect = 0.0
 Identities = 1701/1710 (99%), Positives = 1702/1710 (99%), Gaps = 4/1710 (0%)

Query: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVASSEEVSEERDDLGPLELHD 60
            MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAV SSEEVSEERDDLGPLELHD
Sbjct: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHD 60

Query: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120
            SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV
Sbjct: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120

Query: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180
            PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL
Sbjct: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180

Query: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240
            VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR
Sbjct: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240

Query: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300
            LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH
Sbjct: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300

Query: 301  YNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEVLFVTQVLRQILEL 360
            +NPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLE LFVTQVLRQIL L
Sbjct: 301  HNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEALFVTQVLRQILGL 360

Query: 361  SVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKF 420
            SVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKF
Sbjct: 361  SVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKF 420

Query: 421  FFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILH 480
            FFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILH
Sbjct: 421  FFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILH 480

Query: 481  IIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDTVKI 540
            IIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDTVKI
Sbjct: 481  IIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDTVKI 540

Query: 541  ITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKSRQV 600
            ITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKSRQV
Sbjct: 541  ITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKSRQV 600

Query: 601  DLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRYLE 660
            DLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRYLE
Sbjct: 601  DLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRYLE 660

Query: 661  EHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRA 720
            EHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRA
Sbjct: 661  EHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRA 720

Query: 721  LGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEE 780
            LGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEE
Sbjct: 721  LGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEE 780

Query: 781  RIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHH 840
            RIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHH
Sbjct: 781  RIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHH 840

Query: 841  YVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVS 900
            YVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVS
Sbjct: 841  YVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVS 900

Query: 901  PVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANALSSL 960
            PVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANALSSL
Sbjct: 901  PVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANALSSL 960

Query: 961  EQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMWIYVHSTAVCIHL 1020
            EQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLM IYVHSTAVCIHL
Sbjct: 961  EQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVCIHL 1020

Query: 1021 KLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKCKGD 1080
            KLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKCKGD
Sbjct: 1021 KLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKCKGD 1080

Query: 1081 LQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQ 1140
            LQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQ
Sbjct: 1081 LQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQ 1140

Query: 1141 MRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPME 1200
            MRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPME
Sbjct: 1141 MRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPME 1200

Query: 1201 SHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIH 1260
            SHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIH
Sbjct: 1201 SHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIH 1260

Query: 1261 LLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRV 1320
            LLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRV
Sbjct: 1261 LLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRV 1320

Query: 1321 TIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAE 1380
            TIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAE
Sbjct: 1321 TIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAE 1380

Query: 1381 LVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLEKGADQEEDEALR 1440
            LVLRGMDSEVLSCRISSTAVCVE    FMSGPVLYQEKLLKPAALLLEKGADQEEDEALR
Sbjct: 1381 LVLRGMDSEVLSCRISSTAVCVE----FMSGPVLYQEKLLKPAALLLEKGADQEEDEALR 1436

Query: 1441 VLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGD 1500
            VLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGD
Sbjct: 1437 VLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGD 1496

Query: 1501 VGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLH 1560
            VGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLH
Sbjct: 1497 VGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLH 1556

Query: 1561 SQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCSILTRKKPA 1620
            SQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCSILTRKKPA
Sbjct: 1557 SQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCSILTRKKPA 1616

Query: 1621 VLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPD 1680
            VLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPD
Sbjct: 1617 VLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPD 1676

Query: 1681 PGVRRAALETLTVLDSCSQHGFLASPQGMS 1710
            PGVRRAALETLTVLDSCSQHGFLASPQGMS
Sbjct: 1677 PGVRRAALETLTVLDSCSQHGFLASPQGMS 1706


>gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1723

 Score = 3289 bits (8529), Expect = 0.0
 Identities = 1689/1727 (97%), Positives = 1692/1727 (97%), Gaps = 21/1727 (1%)

Query: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVASSEEVSEERDDLGPLELHD 60
            MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAV SSEEVSEERDDLGPLELHD
Sbjct: 1    MCIGPRAELFLVVNICLIQKKTLRKELEEEMTEAITEAAVDSSEEVSEERDDLGPLELHD 60

Query: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120
            SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV
Sbjct: 61   SGTFQQVVNLLDIIDSESAKTDTTGAGLDMRKTLASVIIMEKATTEPSVVINTLIRCLQV 120

Query: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180
            PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL
Sbjct: 121  PEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTL 180

Query: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240
            VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR
Sbjct: 181  VALSRNHFSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLR 240

Query: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300
            LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH
Sbjct: 241  LANEAKIRQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRH 300

Query: 301  YNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEV---LFVTQVLRQI 357
            +NPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQG   +       QVLRQI
Sbjct: 301  HNPEVKLGVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGKGHLPPFANPLQVLRQI 360

Query: 358  LELSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL 417
            L LSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL
Sbjct: 361  LGLSVTTNTPVPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKEL 420

Query: 418  MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA 477
            MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA
Sbjct: 421  MKFFFSQMETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMA 480

Query: 478  ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT 537
            ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT
Sbjct: 481  ILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDT 540

Query: 538  VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS 597
            VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS
Sbjct: 541  VKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEHQLHGQDVDVSVAGKS 600

Query: 598  RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR 657
            RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR
Sbjct: 601  RQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVR 660

Query: 658  YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL 717
            YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL
Sbjct: 661  YLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFL 720

Query: 718  YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD 777
            YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD
Sbjct: 721  YRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHD 780

Query: 778  FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI 837
            FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI
Sbjct: 781  FEERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKI 840

Query: 838  IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN 897
            IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN
Sbjct: 841  IHHYVSSCQDICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDN 900

Query: 898  LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL 957
            LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL
Sbjct: 901  LVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKTLYANAL 960

Query: 958  SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMWIYVHSTAVC 1017
            SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLM IYVHSTAVC
Sbjct: 961  SSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMRIYVHSTAVC 1020

Query: 1018 IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC 1077
            IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC
Sbjct: 1021 IHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKC 1080

Query: 1078 KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAF 1137
            KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIA 
Sbjct: 1081 KGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAS 1140

Query: 1138 FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL 1197
            FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL
Sbjct: 1141 FLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPL 1200

Query: 1198 PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC 1257
            PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC
Sbjct: 1201 PMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLC 1260

Query: 1258 TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL 1317
            TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL
Sbjct: 1261 TIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNL 1320

Query: 1318 Q-----RVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE 1372
            Q     RVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE
Sbjct: 1321 QRCSRGRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVE 1380

Query: 1373 GHRQRLAELVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLEKGAD 1432
            GHRQRLAELVLRGMDSEVLSCRISSTAVCVE    FMSGPVLYQEKLLKPAALLLEKGAD
Sbjct: 1381 GHRQRLAELVLRGMDSEVLSCRISSTAVCVE----FMSGPVLYQEKLLKPAALLLEKGAD 1436

Query: 1433 QEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKI 1492
            QEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKI
Sbjct: 1437 QEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEALTKI 1496

Query: 1493 LAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKK 1552
            LAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKK
Sbjct: 1497 LAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKK 1556

Query: 1553 AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCS 1612
            AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDT TDDKMT+FQTTMCS
Sbjct: 1557 AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTIFQTTMCS 1616

Query: 1613 ILTRK---------KPAVLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKL 1663
            IL RK         KPAVLYRFLL TMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKL
Sbjct: 1617 ILVRKPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKL 1676

Query: 1664 DFPALRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS 1710
            DFPALRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS
Sbjct: 1677 DFPALRNSLQELQLDPDPGVRRAALETLTVLDSCSQHGFLASPQGMS 1723


>gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]
          Length = 1585

 Score =  656 bits (1692), Expect = 0.0
 Identities = 474/1617 (29%), Positives = 814/1617 (50%), Gaps = 111/1617 (6%)

Query: 128  KVNIYNILQDIIQQEGELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNH 187
            K +IY+ L  +IQ    L++  VQRL+  ASK+MR+   +       +A + LV+L+ + 
Sbjct: 30   KEDIYSHLTSVIQNTDILDDAIVQRLIYYASKDMRDNNMLREIRM--LAGEVLVSLAAHD 87

Query: 188  FSLVMYELQHHLKPLNLTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKI 247
            F+ VMYE+Q + + L L DEFV++ LA+LA   V + +P+M +TL T+ TMLRLA + ++
Sbjct: 88   FNSVMYEVQSNFRILELPDEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLAEDERM 147

Query: 248  RQAICSAMETFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHYNPEVKL 307
            +   C A+E F + +  Y+ H  +  YP +     + K+F ++ Y +  W    +P   L
Sbjct: 148  KGTFCIALEKFSKAIYKYVNHWRDFPYPRLDANRLSDKIFMLFWYIMEKWAPLASPMQTL 207

Query: 308  GVIKSLKPMLGLLLPNDDLREQVYDYIPLLLAEYQGSLEVLFVTQVLRQILELSVTTNTP 367
             ++K+  P + LLL  +D R      +P LL +Y+       VTQ L+QIL  +V  +  
Sbjct: 208  SIVKAHGPTVSLLLHREDFRGYALGQVPWLLNQYKDKEIDFHVTQSLKQILTAAVLYDIG 267

Query: 368  VPQMQLHTIFTELHVQVCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQMET 427
            +P+    +IF  L  Q+C    A      +N M+   CF+ LA S P ELM+FF  Q+ +
Sbjct: 268  LPRSLRRSIFINLLQQICR---APEPPVKENEMKASSCFLILAHSNPGELMEFFDEQVRS 324

Query: 428  NKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILHIIGQLAL 487
            N EA+RVG L L+R  V+ADEPR+    I +  R VK  + D  +KVR ++L +I  +  
Sbjct: 325  NNEAIRVGILTLLRLAVNADEPRLRDHIISIE-RTVKIVMGDLSTKVRNSVLLLIQTMCE 383

Query: 488  CGYQERIKGWGLKYLSVQLTLSTYKLTNR------REKFYQRDLEERMVHKVTMDTVKII 541
              Y E  +GW L    +    S +   NR      +  F++ + EE  V + +++ +K +
Sbjct: 384  KSYIEAREGWPL----IDYVFSQFATLNRNLEKPVKTNFHENEKEEESVRETSLEVLKTL 439

Query: 542  TSSVSGMTTEFWVRLLCYIMETDYVEALTPI--CISLTNLAEH-QLHGQDVDVSVAGKSR 598
               V GM    W R+L +++  +Y EAL P+   I +  +AE  + H      ++   + 
Sbjct: 440  DPLVIGMPQVLWPRILTFVVPAEYTEALEPLFSIIRILIMAEEKKQHSAKESTALVVSTG 499

Query: 599  QVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRY 658
             V LP+PQ+LLARLLV+      GE RG   + LL+ L + I P + D+W+  +  L++ 
Sbjct: 500  AVKLPSPQQLLARLLVISMPASLGELRGAGAIGLLKILPEIIHPKLVDLWKTRLPELLQP 559

Query: 659  LEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLY 718
            LE     T     WE  L+Q L+ SL K    +W+++L+++   Q+ S+ + S EK FL+
Sbjct: 560  LEGKNIST---VLWETMLLQLLKESLWKISDVAWTIQLTQDFKQQMGSYSNNSTEKKFLW 616

Query: 719  RALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDF 778
            +ALG TLA   ++  V   + E L   +   D   +G+    G CA   +  VL VL  F
Sbjct: 617  KALGTTLACCQDSDFVNSQIKEFLTAPNQLGD-QRQGITSILGYCAENHLDIVLKVLKTF 675

Query: 779  EERIQESEQSWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKII 838
                 ++++ + ++  +     ++   K+ +MV+Y  VA +   + LL+ ++  I ++++
Sbjct: 676  -----QNQEKFFMNRCKSLFSGKKSLTKTDVMVIYGAVALHAPKKQLLSRLNQDIISQVL 730

Query: 839  HHYVSSCQ---------DICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAV 889
              +    Q         D+ L+M+F +S+ ++  A+ + +D + F F+ K  L   ++  
Sbjct: 731  SLHGQCSQVLGMSVMNKDMDLQMSFTRSITEIGIAVQDAED-QGFQFSYKEMLIGYMLDF 789

Query: 890  IKAEPTDNLVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIHSVISL----QLPGE- 944
            I+ EP D+L SP+R  A+ A+ +LSKLKP  S +++  +++ +I  ++ L     L  E 
Sbjct: 790  IRDEPLDSLASPIRWKALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLPPLENLKSEG 849

Query: 945  ----DNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAV 1000
                D E I+ LY  ++ +L +L+++++   ++ +  QEM  LL+ W++S+KEWERE+A 
Sbjct: 850  QTDKDKEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQMWLVSQKEWERERAF 909

Query: 1001 SLHLYLMWIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHAS 1060
             +   ++   + +       +  + G+++GL+AP +CD     R A+    SS + L   
Sbjct: 910  QITAKVLTNDIEAP------ENFKIGSLLGLLAPHSCDTLPTIRQAA---ASSTIGLFYI 960

Query: 1061 QTCSLWGPSKQKELEKCKGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENT 1120
            +   L    + + L+  +  L+S DV+     SS+IAK+V      +E++  ++++ +  
Sbjct: 961  KGIHL----EVERLQGLQEGLESDDVQVQIKISSKIAKIVSKFIPNEEILMFLEEMLDGL 1016

Query: 1121 GAMNLQHDKASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVDHPEVR-RLLIDGILL 1179
             ++N    KA   W+   L+ +   LED++ EIL  I  H+PV+   E   + +++ I  
Sbjct: 1017 ESLNPTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAISQ 1076

Query: 1180 LAHHHQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISAT 1239
            +A  H +T++ +LL++PLP +     +W A++E    +  +L +L+ +L++ L   I   
Sbjct: 1077 IASFHMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDI--- 1133

Query: 1240 SKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLGS---------- 1289
                    A V+ +   C ++ +I        +    P+L +TLLL+L S          
Sbjct: 1134 --------ARVEAISVACAMYEVISM---GTSVTGLYPEL-FTLLLKLVSCTLGQKMLTC 1181

Query: 1290 --SHRPEAAPPVLKMWKLVHTTPLPEEMNLQRVTIKSMQLLFKRVKSQHLAHTLDE-QAV 1346
              SHR         + +      +P+   L   T+K +Q    R   + LA   DE   +
Sbjct: 1182 PWSHRRH-------VMQQGEQQQIPDPCRLSTATLKCLQAQAMR---EGLAKESDEGDNL 1231

Query: 1347 WDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAELVLRGMDSEVLSCRISSTAVCVEMRH 1406
            W LL    T   GV  LAR       G    + E +L  + S   + RI+  A   E+  
Sbjct: 1232 WTLLSSPSTHHIGVCSLARSMAVWQHGVILDIMEQLLSSLTSSSENYRITGAAFFSEL-- 1289

Query: 1407 RFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLL 1466
              M  P+L++   L+   +L+++ A  + +  LR +++R LGN A GAP KVK++++++L
Sbjct: 1290 --MKEPILWKHGNLRNVLILMDQSA-WDSNATLRQMAIRGLGNTASGAPHKVKKHKQLML 1346

Query: 1467 EKCLGPLREPVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLK 1526
            E  +  L       V  E ++AL KIL  L + DV   F  +  Q R FF++E + +RL 
Sbjct: 1347 ESIIRGLYHLARTEVVCESLKALKKILELLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLT 1406

Query: 1527 AFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWK 1586
            A  LF  LA + G   K FF  E+KK+ I  +LH  DP      AC   +  C+ F G  
Sbjct: 1407 AIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNPKIGVACRDVLMVCIPFLG-- 1464

Query: 1587 SLEHPSGPSDTATDD---KMTVFQTTMCSILTRKKPAVLYRFLLETMAYVKNNLSRIRIA 1643
             L+   G  D   D    +   F    C  L +K   +L+     +  +  +    IR A
Sbjct: 1465 -LQELYGVLDRLLDQDLPRARDFYRQFCVKLAKKNQEILWILHTHSFTFFTSTWEVIRSA 1523

Query: 1644 ACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAALETL-TVLDSCSQ 1699
            A  L   ++  +++ Y++ LD   L   LQ L+ DP   V+RAA   L T+L  C +
Sbjct: 1524 AVKLTDAVVLNLTSQYVELLDREQLTTRLQALRQDPCISVQRAAEAALQTLLRRCKE 1580


>gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]
          Length = 1641

 Score =  600 bits (1548), Expect = e-171
 Identities = 446/1584 (28%), Positives = 756/1584 (47%), Gaps = 64/1584 (4%)

Query: 144  ELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHLKPLN 203
            EL++     ++ +AS EM +  ++    + + AS  LVA+ R   S VM EL   L P  
Sbjct: 79   ELDKDTASTIILLASSEMTKTKDLVWDWQ-QAASGVLVAVGRQFISKVMEELLRRLHPGT 137

Query: 204  LTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKIRQAICSAMETFCETVQ 263
            L    V+ TLA L+  N F  +P++   L+++  +L +A +  +R A CSA++ F E   
Sbjct: 138  LPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGAL 197

Query: 264  FYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHYNPEVKLGVIKSLKPMLGLLLPN 323
             YL +L+ +  P + ++ FA  +F  Y      WL+    +++L V+++L PM   LLP+
Sbjct: 198  EYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPM-SHLLPS 256

Query: 324  DDLREQVYDYIPLLLAEYQGSLEVLFVTQVLRQILELSVTTNTPVPQMQLHTIFTELHVQ 383
            + L EQ+   +P +LA Y+   E  ++++ L QILE +V+  +   + QL  +   LH Q
Sbjct: 257  ERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQ 316

Query: 384  VCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQMETNKEAVRVGTLNLIRAI 443
            +C    +       N  E++ CF  LA S P  L+ F   +++T+ E  RVGTL ++R +
Sbjct: 317  ICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHV 376

Query: 444  VSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILHIIGQLALCGYQERIKGWGLKYLS 503
            +++   +M  +  ++ +  ++  + DT SKV+ A++ +I  +A  GY E+  G  +    
Sbjct: 377  INSAAAQMEDKKPFI-LSSMRLPLLDTNSKVKRAVVQVISAMAHHGYLEQPGGEAMIEYI 435

Query: 504  VQLTLSTYKLTNRREKFYQRDLEERMVHKVTMDTVKIITSSVSGMTTEFWVRLLCYIMET 563
            VQ      +    +     +D +   V  +++ T+ +++++V  M+   W  LL ++   
Sbjct: 436  VQQCALPPEQEPEKPGPGSKDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFLTPV 495

Query: 564  DYVEALTPICISLTNLAEHQLHGQDVDVSVAGKSRQVDLPAPQKLLARLLVLMSSPYKGE 623
             +  ALTP+C SL +LA+ +      D  +        LP+P  +  RLLV+ SSPY G+
Sbjct: 496  RFTGALTPLCRSLVHLAQKRQEA-GADAFLIQYDAHASLPSPYAVTGRLLVVSSSPYLGD 554

Query: 624  GRGIAMLNLLRTLSQSIAPSMADMWELEIALLVRYLEEHTEFTWDQKAWEDKLIQFLRNS 683
            GRG A L LL  L  +I P +   WE  + LL+ YL+EHTE T  Q+ WE+KL+ FLR++
Sbjct: 555  GRGAAALRLLSVLHPNIHPLLGQHWETTVPLLLGYLDEHTEETLPQEEWEEKLLMFLRDT 614

Query: 684  LKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRALGFTLATGLEASKVEVLLLELLY 743
            L     ++W  +LS EL  Q+  +D    EK FLY+ +G TL        V   L ELL 
Sbjct: 615  LAIISDNAWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQELLE 674

Query: 744  KTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEERIQESEQSWQISAWRKDHPWRR- 802
               Y  + + EG+  CFG+CA   ++  L  L DF  R +   +S  I    KD      
Sbjct: 675  TARYQEEAEREGLACCFGICAISHLEDTLAQLEDF-VRSEVFRKSIGILNIFKDRSENEV 733

Query: 803  ETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHHYVS-------SCQDICLKMAFM 855
            E VKSAL++ Y  VA+    +L+L  V+S I   I  H+ +         +D  LK+  +
Sbjct: 734  EKVKSALILCYGHVAARAPRELVLAKVESDILRNICQHFSTKVLGIKVETKDPALKLCLV 793

Query: 856  KSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAMEALSHLSK 915
            +SV  V++AI +      FHF +K  L + ++  I+AEP D+L +P+R  AM   ++L  
Sbjct: 794  QSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTYLVS 853

Query: 916  LKPFYSTEENSELMDISIHSVISL--QLPGEDNESIKTLYANALSSLEQLMESLLQRQLD 973
            ++P    +  ++++   +HS+++L  +   ED    K+LY   L +LE L+ SLLQR + 
Sbjct: 854  VEPALDEQARADVIHGCLHSIMALLPEPKEEDGGCQKSLYLETLHALEDLLTSLLQRNMT 913

Query: 974  PKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMWIYVHSTAVCIHLKLGQFGTMVGLIA 1033
            P+GLQ M++ L  WI S +  ER +A+ L   L+  ++    V   +     G ++GL +
Sbjct: 914  PQGLQIMIEHLSPWIKSPRGHERARALGLSALLLRYFLEHLRVSALVPFHNLGLLIGLFS 973

Query: 1034 PCTCDAHQRTRMASMNVLSSLLDLHASQT--CSLWGPSKQKELEKCKGDLQSTDVEKIFC 1091
            P   D    TR  +++ + SLL L          +     + L   K  L   D   +F 
Sbjct: 974  PRCADLWPATRQEAVDCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAILFH 1033

Query: 1092 ASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQMRAKELEDKVA 1151
                + +++      D+++SL+  + E  G       +A+   I   LQ R   L++KV 
Sbjct: 1034 TCHSVGQIIAKRLPPDQLISLLLTMFEALGDPEKNCSRAATVMINCLLQERGGVLQEKVP 1093

Query: 1152 EILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPMESHLAEVWLAVS 1211
            EI+S +   L       V       + LLA  H   +++SLL  PLP++SH   +W A++
Sbjct: 1094 EIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAAVVSSLLGSPLPLDSHTCMLWRALA 1153

Query: 1212 ENVPFARTMLHSLMGRLQSRLSPRISATSKADIW-----RLAAVDPLMTLCTIHLLIQKL 1266
                 A  +L  L+ ++ SR  P     S+A +      R+A + PL   C +  ++   
Sbjct: 1154 VEPRLAAQVLGLLLEKM-SRDVP--FKESRAFLLGRTPDRVATLLPLSATCALFEVMSTP 1210

Query: 1267 DENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRVT--IKS 1324
                 + +  P L   LLL++  +   +  P  L+  +    +P     NL+  +  + +
Sbjct: 1211 AAGPAVLELYPQLFVVLLLRVSCTVGVQ-LPRNLQAQERRGASPALATRNLEPCSSAVDT 1269

Query: 1325 MQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAELVLR 1384
            ++ +  R  S+ +   +D +  W+LL+      EG + LAR   +H       + + +  
Sbjct: 1270 LRSMLLRSGSEDVVQRMDLEGGWELLRTSAGHEEGATRLARAMAEHAGPRLPLVLKTLAC 1329

Query: 1385 GMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLSL 1444
               S   + R+++TA   E+ +  ++  ++  + LL+  A        ++   ++R L L
Sbjct: 1330 THSSAYENQRVTTTAFLAELLNSNVANDLMLLDSLLESLA-----ARQKDTCASVRRLVL 1384

Query: 1445 RALGNMALGAPKKVKQYRKVLLEKCLGPLREPVS--NSVTAEGMEALTKILAELREGDVG 1502
            R L N+A G P KV+ +   LL   +G L +  +  + V  E M  L +++  +   D+ 
Sbjct: 1385 RGLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPVALEAMLGLARLVHLVESWDLR 1444

Query: 1503 SSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQ 1562
            S    ++ + R FFD+E    R  +  LFG L +V     +  F  +V     PL+LH Q
Sbjct: 1445 SGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGLAPLLLHLQ 1504

Query: 1563 DPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQ--------------- 1607
            DP +  A AC   +  C             GP + A ++    FQ               
Sbjct: 1505 DPQATVASACRFALRMC-------------GP-NLACEELSAAFQKHLQEGRALHFGEFL 1550

Query: 1608 TTMCSILTRKKPAVLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPA 1667
             T C  L    P +L R L   + Y K++   +R AA    G ++         ++D   
Sbjct: 1551 NTTCKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAAAPLFTGFLVLHSEPRQQPQVDLDQ 1610

Query: 1668 LRNSLQELQLDPDPGVRRAALETL 1691
            L  +LQ L  DP P VR  A E L
Sbjct: 1611 LIAALQILLKDPAPEVRTRAAEAL 1634


>gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5
            [Homo sapiens]
          Length = 1218

 Score =  434 bits (1116), Expect = e-121
 Identities = 337/1205 (27%), Positives = 561/1205 (46%), Gaps = 61/1205 (5%)

Query: 523  RDLEERMVHKVTMDTVKIITSSVSGMTTEFWVRLLCYIMETDYVEALTPICISLTNLAEH 582
            +D +   V  +++ T+ +++++V  M+   W  LL ++    +  ALTP+C SL +LA+ 
Sbjct: 32   KDPKADSVRAISVRTLYLVSTTVDRMSHVLWPYLLQFLTPVRFTGALTPLCRSLVHLAQK 91

Query: 583  QLHGQDVDVSVAGKSRQVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAP 642
            +      D  +        LP+P  +  RLLV+ SSPY G+GRG A L LL  L  +I P
Sbjct: 92   RQEA-GADAFLIQYDAHASLPSPYAVTGRLLVVSSSPYLGDGRGAAALRLLSVLHPNIHP 150

Query: 643  SMADMWELEIALLVRYLEEHTEFTWDQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNN 702
             +   WE  + LL+ YL+EHTE T  Q+ WE+KL+ FLR++L     ++W  +LS EL  
Sbjct: 151  LLGQHWETTVPLLLGYLDEHTEETLPQEEWEEKLLMFLRDTLAIISDNAWICQLSLELCR 210

Query: 703  QIASFDSPSLEKGFLYRALGFTLATGLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGL 762
            Q+  +D    EK FLY+ +G TL        V   L ELL    Y  + + EG+  CFG+
Sbjct: 211  QLPCYDEAPQEKNFLYKCIGTTLGAASSKEVVRKHLQELLETARYQEEAEREGLACCFGI 270

Query: 763  CARGQVKTVLNVLHDFEERIQESEQSWQISAWRKDHPWRR-ETVKSALMVMYSCVASYCH 821
            CA   ++  L  L DF  R +   +S  I    KD      E VKSAL++ Y  VA+   
Sbjct: 271  CAISHLEDTLAQLEDF-VRSEVFRKSIGILNIFKDRSENEVEKVKSALILCYGHVAARAP 329

Query: 822  PQLLLNLVDSPITAKIIHHYVS-------SCQDICLKMAFMKSVVQVTKAINNIKDLEDF 874
             +L+L  V+S I   I  H+ +         +D  LK+  ++SV  V++AI +      F
Sbjct: 330  RELVLAKVESDILRNICQHFSTKVLGIKVETKDPALKLCLVQSVCMVSRAICSSTQAGSF 389

Query: 875  HFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAMEALSHLSKLKPFYSTEENSELMDISIH 934
            HF +K  L + ++  I+AEP D+L +P+R  AM   ++L  ++P    +  ++++   +H
Sbjct: 390  HFTRKAELVAQMMEFIRAEPPDSLRTPIRKKAMLTCTYLVSVEPALDEQARADVIHGCLH 449

Query: 935  SVISL--QLPGEDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSEK 992
            S+++L  +   ED    K+LY   L +LE L+ SLLQR + P+GLQ M++ L  WI S +
Sbjct: 450  SIMALLPEPKEEDGGCQKSLYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWIKSPR 509

Query: 993  EWEREKAVSLHLYLMWIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLS 1052
              ER +A+ L   L+  ++    V   +     G ++GL +P   D    TR  +++ + 
Sbjct: 510  GHERARALGLSALLLRYFLEHLRVSALVPFHNLGLLIGLFSPRCADLWPATRQEAVDCVY 569

Query: 1053 SLLDLHASQT--CSLWGPSKQKELEKCKGDLQSTDVEKIFCASSRIAKVVCMEFSCDEVV 1110
            SLL L          +     + L   K  L   D   +F     + +++      D+++
Sbjct: 570  SLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAILFHTCHSVGQIIAKRLPPDQLI 629

Query: 1111 SLIQKLCENTGAMNLQHDKASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVDHPEVR 1170
            SL+  + E  G       +A+   I   LQ R   L++KV EI+S +   L       V 
Sbjct: 630  SLLLTMFEALGDPEKNCSRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVL 689

Query: 1171 RLLIDGILLLAHHHQETILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQS 1230
                  + LLA  H   +++SLL  PLP++SH   +W A++     A  +L  L+ ++ S
Sbjct: 690  PAAQHSVYLLATQHCAAVVSSLLGSPLPLDSHTCMLWRALAVEPRLAAQVLGLLLEKM-S 748

Query: 1231 RLSPRISATSKADIW-----RLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLL 1285
            R  P     S+A +      R+A + PL   C +  ++        + +  P L   LLL
Sbjct: 749  RDVP--FKESRAFLLGRTPDRVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVVLLL 806

Query: 1286 QLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRVT--IKSMQLLFKRVKSQHLAHTLDE 1343
            ++  +   +  P  L+  +    +P     NL+  +  + +++ +  R  S+ +   +D 
Sbjct: 807  RVSCTVGVQ-LPRNLQAQERRGASPALATRNLEPCSSAVDTLRSMLLRSGSEDVVQRMDL 865

Query: 1344 QAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLAELVLRGMDSEVLSCRISSTAVCVE 1403
            +  W+LL+      EG + LAR   +H       + + +     S   + R+++TA   E
Sbjct: 866  EGGWELLRTSAGHEEGATRLARAMAEHAGPRLPLVLKTLACTHSSAYENQRVTTTAFLAE 925

Query: 1404 MRHRFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRK 1463
            + +  ++  ++  + LL+  A        ++   ++R L LR L N+A G P KV+ +  
Sbjct: 926  LLNSNVANDLMLLDSLLESLA-----ARQKDTCASVRRLVLRGLANLASGCPDKVRTHGP 980

Query: 1464 VLLEKCLGPLREPVS--NSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESE 1521
             LL   +G L +  +  + V  E M  L +++  +   D+ S    ++ + R FFD+E  
Sbjct: 981  QLLTAMIGGLDDGDNPHSPVALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKM 1040

Query: 1522 LLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQCVH 1581
              R  +  LFG L +V     +  F  +V     PL+LH QDP +  A AC   +  C  
Sbjct: 1041 EFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGLAPLLLHLQDPQATVASACRFALRMC-- 1098

Query: 1582 FWGWKSLEHPSGPSDTATDDKMTVFQ---------------TTMCSILTRKKPAVLYRFL 1626
                       GP + A ++    FQ                T C  L    P +L R L
Sbjct: 1099 -----------GP-NLACEELSAAFQKHLQEGRALHFGEFLNTTCKHLMHHFPDLLGRLL 1146

Query: 1627 LETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRA 1686
               + Y K++   +R AA    G ++         ++D   L  +LQ L  DP P VR  
Sbjct: 1147 TTCLFYFKSSWENVRAAAPLFTGFLVLHSEPRQQPQVDLDQLIAALQILLKDPAPEVRTR 1206

Query: 1687 ALETL 1691
            A E L
Sbjct: 1207 AAEAL 1211


>gi|148727311 hypothetical protein LOC389690 [Homo sapiens]
          Length = 1318

 Score =  206 bits (524), Expect = 2e-52
 Identities = 255/1105 (23%), Positives = 444/1105 (40%), Gaps = 105/1105 (9%)

Query: 668  DQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRALGFTLAT 727
            D+  WE++LIQ    S+       WS  L   L     +    S EK FL+   G  L  
Sbjct: 240  DKACWEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQA 299

Query: 728  GLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEERIQESEQ 787
                + V   L  LL +T +      EG+ +  GL A   +  V  VL  F  R +    
Sbjct: 300  EKNGATVRRHLQALL-ETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFG-RSRPIRW 357

Query: 788  SWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHHYVSSCQD 847
            S   S+ +     R +   S +++ Y  VA+     +L   VD+ I ++++ ++  S  D
Sbjct: 358  SLPSSSPKNSEDLRWKWASSTILLAYGQVAAKARAHIL-PWVDN-IVSRMVFYFHYSSWD 415

Query: 848  ICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAM 907
              LK +F+ + + +  A++  +    + F Q + L   ++ +++ EP D L +  R  AM
Sbjct: 416  ETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQAM 475

Query: 908  EALSHLSKLKPFYSTEENSELMDISIHSVISLQLPG------------------------ 943
               S L KL+P    E  S+L+     SV +L L                          
Sbjct: 476  HIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARER 535

Query: 944  --------------EDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWIL 989
                            +E +++LY+  + +L+ +++SL+ +      L  ++  L  W+ 
Sbjct: 536  AGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLA 595

Query: 990  SEKEWEREKAVSLHLYLMWIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMN 1049
            SEK  ER++AV   + L+    H+  +       + G +VG++     D  + T+  S+ 
Sbjct: 596  SEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLE 655

Query: 1050 VLSSLLDL------------------HASQTCS----LWGPSKQKELEKCKGDLQSTDVE 1087
              S L  L                    SQ  S    LW    QK       ++    + 
Sbjct: 656  GASHLYQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIF 715

Query: 1088 KIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQMRAKELE 1147
            ++   S ++ K +  + +  E+  LI    +  G+ +    +A+   +   +Q    +LE
Sbjct: 716  QL--CSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLE 773

Query: 1148 DKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPMESHLAEVW 1207
              V+ +  AI + L  V  P+ +   +  I LLA  H   ++ + L   +P++SH  ++W
Sbjct: 774  I-VSSMAQAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLW 832

Query: 1208 LAVSENVPFARTMLHSLMGRLQSRLSPRISATS------KADIWRLAAVDPLMTLCTIHL 1261
             A+    P +  +L +L+  LQ R  P  ++ S      K  +  LAA++ L  L     
Sbjct: 833  RALGAGQPTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFARE 892

Query: 1262 LIQKLDEN--DKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQR 1319
              Q + E         L  + Y L L L S  +P       K        P P+  +   
Sbjct: 893  FKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQP-------KQQAQEAAVPSPQSCSTSL 945

Query: 1320 VTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLA 1379
              +KS  LL         AH L+ Q  W+L     T+ +GV LLAR  +Q+      R  
Sbjct: 946  EALKS--LLSTTGHWHDFAH-LELQGSWELFTTIHTYPKGVGLLARAMVQN----HCRQI 998

Query: 1380 ELVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLEKGADQEEDEAL 1439
              VLR +   + S +     V + +  +F+  PVL  E L K AAL +      +    +
Sbjct: 999  PAVLRQLLPSLQSPQERERKVAILILTKFLYSPVLL-EVLPKQAALTVLAQGLHDPSPEV 1057

Query: 1440 RVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPV---SNSVTAEGMEALTKILAEL 1496
            RVLSL+ L N+     K        LL+  L PL +     S+ V    M  ++  L  L
Sbjct: 1058 RVLSLQGLSNILFHPDKGS------LLQGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRL 1111

Query: 1497 REGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIP 1556
                 GS    ++   R FF++E + +R  A  LFG L   +   +    + +V ++ +P
Sbjct: 1112 GAQGTGSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVP 1171

Query: 1557 LMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCSILTR 1616
            L+LH +D C   A     T ++C     W+ L   +     A +  ++        ++TR
Sbjct: 1172 LLLHLKDQCPAVATQAKFTFYRCAVLLRWRLLH--TLFCTLAWERGLSARHFLWTCLMTR 1229

Query: 1617 KKPAVLYRFLLETMAYVKNNLSRIRIAACNLAGIIM---KQMSTHYLKKLDFPALRNSLQ 1673
             +       L + ++Y+ ++   I+       G  +    Q     L  +D   L  + +
Sbjct: 1230 SQEEFSIH-LSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLNAVDTNLLFRTFE 1288

Query: 1674 ELQLDPDPGVRRAALETLTVLDSCS 1698
             L+ DP+P +R  A   L+ L   S
Sbjct: 1289 HLRSDPEPSIREFATSQLSFLQKVS 1313



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 2/102 (1%)

Query: 99  IMEKATTEPSVVINTLIRC-LQVPEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIA 157
           I   A   P +V+ T+    +  PEIS++ K  ++  L+ +I     LEE   +    +A
Sbjct: 112 IKNMAHGSPKLVMETIHDYFIDNPEISSRHKFRLFQTLEMVIGASDVLEETWEKTFTRLA 171

Query: 158 SKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHL 199
            + M +  E+E   + + AS+ LVA+ R+ + +V   L+  L
Sbjct: 172 LENMTKATELEDIYQ-DAASNMLVAICRHSWRVVAQHLETEL 212


>gi|223278410 hypothetical protein LOC374977 [Homo sapiens]
          Length = 1323

 Score =  172 bits (436), Expect = 3e-42
 Identities = 201/901 (22%), Positives = 396/901 (43%), Gaps = 93/901 (10%)

Query: 852  MAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAMEALS 911
            MA +++V  + K+    +DL +    +K T+   I+  I+ EP D+L S VR  AME L+
Sbjct: 433  MALVENVTTLQKS----QDLLEAE-GEKKTMIKKIMRQIQEEPLDSLSSSVRKQAMEILT 487

Query: 912  HLSKLKPFYSTEENSELMDISIHSVISLQ----LPGEDN---ESIKTLYANALSSLEQLM 964
             LS  +P     E SEL+++ +HSV SL     +  +D    E+I+ LY   L +L+ L+
Sbjct: 488  QLSHTQPTLGMRERSELVNVCVHSVFSLPSVQAMQEKDEAKAETIQALYHQTLEALQTLL 547

Query: 965  ESLLQRQLDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMWIYVHSTAVCIHLKLGQ 1024
            ++L      P GL+ +++ L  W+ S K  ER +AV+ ++ ++   + +    + L    
Sbjct: 548  KALFIEDPTPAGLKSILEALGPWMNSGKAHERARAVNTNVSVLNHMLLTLPFFMPLGFPA 607

Query: 1025 FGTMVGLIAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPSKQKELEKCKGDLQST 1084
             G ++G +     D  +     +++ +  L  +               EL+K   D + T
Sbjct: 608  LGLLLGRLILHIGDPDEEIGCEALDGIIILYTI--------------LELQKRARDKEET 653

Query: 1085 DVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQH----------------- 1127
            + ++++ ++            C  ++ +I++  +  G   ++                  
Sbjct: 654  NKKELYESNKHFLGPYNPVSPCQNILRVIEEFGDFLGPQQIKDLLLAALEGLKGSSEAPG 713

Query: 1128 -------DKASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLL 1180
                     AS   ++  L+       + + EI+  I + L  +  P  R++ +  + LL
Sbjct: 714  KDSREMMQLASEVMLSSVLEWYRHRALEVIPEIMQGIYMQLSHIQEPRARQVALLPVSLL 773

Query: 1181 AHHHQETILTSLLRQPLPMESHLAEVW--LAVSENVPFARTMLHSLMGRLQSRLSPRISA 1238
            A      ++ +LL  PLP+ S+ AE+W  L + +     R +L  L+G L+ +    ++ 
Sbjct: 774  ASSFMTEVVVALLMCPLPLNSNGAEMWRQLILCKPSCDVRDLLDLLLGSLKEK---PVTK 830

Query: 1239 TSKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQ----LGSSHRPE 1294
              +A I  LAA   L  L +++  + ++          P L+  LL+Q    +G +    
Sbjct: 831  EGRASIVPLAAASGLCELLSVNSCMGRVRR------IYPQLLLALLIQVHYHIGLNLPGC 884

Query: 1295 AAPPVLKMWKLVHTTPLPEEMNLQRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGG 1354
             APP     K       P      R  +K ++ L  R+   +    L++Q  W+L++   
Sbjct: 885  VAPP-----KDTKKGAQPSPFVPVRWVVKVVKTLLLRMGCSYETTFLEDQGGWELMEQVE 939

Query: 1355 TFLEGVSLLARLCMQHVEGHRQRLAELVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVL 1414
            +   GV+LLAR  +Q+      R+  L++  ++      RI++TA  VE+         L
Sbjct: 940  SHHRGVALLARAMVQYSCQELCRILYLLIPLLERGDEKHRITATAFFVEL---------L 990

Query: 1415 YQEKLLK-PAALLLEKGAD--QEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLG 1471
              E++ + P    L + A+     D  ++VLS+R L  +A  + K  K   K LL   + 
Sbjct: 991  QMEQVRRIPEEYSLGRMAEGLSHHDPIMKVLSIRGLVILARRSEKTAKV--KALLPSMVK 1048

Query: 1472 PLREPVSNSVTAEGMEALTKILAELREGDVGSS-FDAMSEQCRIFFDNESELLRLKAFIL 1530
             L+  +   +  E +  L  +     +  + S+ +  M +     F +  E++R     L
Sbjct: 1049 GLKN-MDGMLVVEAVHNLKAVFKGRDQKLMDSAVYVEMLQILLPHFSDAREVVRSSCINL 1107

Query: 1531 FGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEH 1590
            +GK+ + +   +    + ++    +PL+L  Q+  S  +Q C+ T+ +C +F  W+ L  
Sbjct: 1108 YGKVVQKLRAPRTQAMEEQLVSTLVPLLLTMQEGNSKVSQKCVKTLLRCSYFMAWE-LPK 1166

Query: 1591 PSGPSDTATDDKMTVFQTTMCSILTRKKPAVLYRFLLETMAYVKNNLSRIRIAACNLAGI 1650
             +       + + TV +   C + T +  A +  FL +++ Y KN+ + +R  +    G 
Sbjct: 1167 RAYSRKPWDNQQQTVAKICKCLVNTHRDSAFI--FLSQSLEYAKNSRASLRKCSVMFIGS 1224

Query: 1651 IMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAALETLT-VLDSCSQHGFLASPQGM 1709
            ++  M +  + +     ++ +L  L+ DP+  V   A +    +L SC Q+ +L  P G 
Sbjct: 1225 LVPCMES-IMTEDRLNEVKAALDNLRHDPEASVCIYAAQVQDHILASCWQNSWL--PHGN 1281

Query: 1710 S 1710
            S
Sbjct: 1282 S 1282


>gi|149944578 HEAT repeat containing 7A isoform 2 [Homo sapiens]
          Length = 422

 Score =  162 bits (409), Expect = 3e-39
 Identities = 94/303 (31%), Positives = 163/303 (53%), Gaps = 2/303 (0%)

Query: 144 ELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHLKPLN 203
           EL++     ++ +AS EM +  ++    + + AS  LVA+ R   S VM EL   L P  
Sbjct: 79  ELDKDTASTIILLASSEMTKTKDLVWDWQ-QAASGVLVAVGRQFISKVMEELLRRLHPGT 137

Query: 204 LTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKIRQAICSAMETFCETVQ 263
           L    V+ TLA L+  N F  +P++   L+++  +L +A +  +R A CSA++ F E   
Sbjct: 138 LPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGAL 197

Query: 264 FYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHYNPEVKLGVIKSLKPMLGLLLPN 323
            YL +L+ +  P + ++ FA  +F  Y      WL+    +++L V+++L PM   LLP+
Sbjct: 198 EYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPM-SHLLPS 256

Query: 324 DDLREQVYDYIPLLLAEYQGSLEVLFVTQVLRQILELSVTTNTPVPQMQLHTIFTELHVQ 383
           + L EQ+   +P +LA Y+   E  ++++ L QILE +V+  +   + QL  +   LH Q
Sbjct: 257 ERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQ 316

Query: 384 VCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQMETNKEAVRVGTLNLIRAI 443
           +C    +       N  E++ CF  LA S P  L+ F   +++T+ E  RVGTL ++R +
Sbjct: 317 ICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHV 376

Query: 444 VSA 446
           +++
Sbjct: 377 INS 379


>gi|149944469 HEAT repeat containing 7A isoform 2 [Homo sapiens]
          Length = 422

 Score =  162 bits (409), Expect = 3e-39
 Identities = 94/303 (31%), Positives = 163/303 (53%), Gaps = 2/303 (0%)

Query: 144 ELEEQCVQRLVAIASKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHLKPLN 203
           EL++     ++ +AS EM +  ++    + + AS  LVA+ R   S VM EL   L P  
Sbjct: 79  ELDKDTASTIILLASSEMTKTKDLVWDWQ-QAASGVLVAVGRQFISKVMEELLRRLHPGT 137

Query: 204 LTDEFVIITLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKIRQAICSAMETFCETVQ 263
           L    V+ TLA L+  N F  +P++   L+++  +L +A +  +R A CSA++ F E   
Sbjct: 138 LPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGAL 197

Query: 264 FYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHYNPEVKLGVIKSLKPMLGLLLPN 323
            YL +L+ +  P + ++ FA  +F  Y      WL+    +++L V+++L PM   LLP+
Sbjct: 198 EYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPM-SHLLPS 256

Query: 324 DDLREQVYDYIPLLLAEYQGSLEVLFVTQVLRQILELSVTTNTPVPQMQLHTIFTELHVQ 383
           + L EQ+   +P +LA Y+   E  ++++ L QILE +V+  +   + QL  +   LH Q
Sbjct: 257 ERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQ 316

Query: 384 VCNKAPAQHQYSSQNLMEMVHCFVALARSYPKELMKFFFSQMETNKEAVRVGTLNLIRAI 443
           +C    +       N  E++ CF  LA S P  L+ F   +++T+ E  RVGTL ++R +
Sbjct: 317 ICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHV 376

Query: 444 VSA 446
           +++
Sbjct: 377 INS 379


>gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapiens]
          Length = 1052

 Score =  151 bits (381), Expect = 6e-36
 Identities = 192/898 (21%), Positives = 374/898 (41%), Gaps = 68/898 (7%)

Query: 832  PITAKIIHHYVSSCQDI--------CLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLT 883
            P++  I+   + S Q +          K+ F+  +  +++A+   +  + F  +    + 
Sbjct: 163  PLSEAIVEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIV 222

Query: 884  SIIVAVIKAEPTDNLVSPVRALAMEALSHLS--KLKPFYSTEENSELMDISIHSVISL-- 939
              +  +++ E   +L S +R      ++ LS   +     +E+ +EL  ++I S+I+L  
Sbjct: 223  HTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPS 282

Query: 940  --------QLPGEDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSE 991
                    ++      + + LY     +  ++++SL+ +    + L  +++ L  W+ S 
Sbjct: 283  VRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSV 342

Query: 992  KEWEREKAVSLHLYLMWIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVL 1051
            K+ ERE+A +    ++        + + L+  + G +V L+A    D  ++    +   +
Sbjct: 343  KDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGI 402

Query: 1052 SSLLDLHASQTCSLWGPSKQKELE----KCKG--DLQSTDVEKIFCASSRIAKVVCMEFS 1105
             SLL +             Q+ L+    KC+   +L S+  +  +    RIA+V      
Sbjct: 403  HSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLD 462

Query: 1106 CDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVD 1165
             +E+   I    +    +     + S   +   L    +   +KV EI+  I   L ++ 
Sbjct: 463  SNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIIS 522

Query: 1166 HPEVRRLLIDGILLLAHHHQET--ILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHS 1223
             P VR+ +I+ + L     + T  +L+ LL  P+P   HLAEVW  +S  +P    +L  
Sbjct: 523  QPRVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWR 582

Query: 1224 LMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTL 1283
            L+ +LQ   +    A  K     +AA D L  +   + L              P L+ TL
Sbjct: 583  LLRKLQKCHNE--PAQEKMAYVAVAATDALYEVFLGNRLRAATFR------LFPQLLMTL 634

Query: 1284 LLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRVTIKSMQLLFKRVKSQHLAHTLDE 1343
            L+Q+  S     +   +    L     +P E+      +++ + L  R       + +++
Sbjct: 635  LIQIHHSIGLTMSDVDIPSG-LYTEQEVPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEK 693

Query: 1344 QAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQR----LAELVLRGMDSEVLSCRISSTA 1399
               W LL      L+G+ LLA   ++  +   Q+    L  L+ RG D      +++S  
Sbjct: 694  NKGWALLGGKDGHLQGLFLLANALLERNQLLAQKVMYLLVPLLNRGNDKH----KLTSAG 749

Query: 1400 VCVEMRHRFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVK 1459
              VE+    +  PV   ++L    ++   K   Q+ +   R+L LR L N+     ++++
Sbjct: 750  FFVEL----LRSPVA--KRLPSIYSVARFKDWLQDGNHLFRILGLRGLYNLV--GHQEMR 801

Query: 1460 QYRKVLLEKCLGPLREPVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNE 1519
            +  K LL   +  LRE     V    + A+  +L  +R  D  +    M     +F D  
Sbjct: 802  EDIKSLLPYIVDSLRETDEKIV----LSAIQILLQLVRTMDFTTLAAMMRTLFSLFGDVR 857

Query: 1520 SELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQC 1579
            S++ R     LFG   + V    K   + +V  + +PL+L+SQD     A+     +  C
Sbjct: 858  SDVHRFSV-TLFGAAIKSVKNPDKKSIENQVLDSLVPLLLYSQDENDAVAEESRQVLTIC 916

Query: 1580 VHFWGWKSLEHPSGPSDTATDDKMTVFQT---TMCSILTRKKPAVLYRFLLETMAYVKNN 1636
              F  WK       P +  + D   +  T   T+C    +K    +   L +T+ Y KN 
Sbjct: 917  AQFLKWKL------PQEVYSKDPWHIKPTEAGTICRFFEKKCKGKI-NILEQTLMYSKNP 969

Query: 1637 LSRIRIAACNLAGIIMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAALETLTVL 1694
               IR +A    G++ K M  + L+++    + + L++L  DP+P +   A +TL ++
Sbjct: 970  KLPIRRSAVLFVGLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEPSLCIIASQTLLLV 1027


>gi|154937380 hypothetical protein LOC642475 [Homo sapiens]
          Length = 719

 Score =  122 bits (306), Expect = 3e-27
 Identities = 135/563 (23%), Positives = 242/563 (42%), Gaps = 34/563 (6%)

Query: 1129 KASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETI 1188
            +A+V  ++  L+ R + LED+V  ++  +L  +P +      R  +  +  LA  H   +
Sbjct: 129  QATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSALALEHARDV 188

Query: 1189 LTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLA 1248
            + +LL + LP +   AE+W ++S N      +L  L+  L+    P   A        LA
Sbjct: 189  VCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQA--------LA 240

Query: 1249 AVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHT 1308
            A   L  +  +   +           F P L+  L+ QL    R   +P + K+W L H 
Sbjct: 241  ATRALGEMLAVSGCV------GATRGFYPHLLLALVTQLHKLARSPCSPDMPKIWVLSHR 294

Query: 1309 TPLPEEMNLQRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCM 1368
             P     +     +++++ L      + +   +++   W  L    T LEGV LLA   +
Sbjct: 295  GPPHSHASC---AVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMV 351

Query: 1369 QHVEGHRQRLAELVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLE 1428
             H + H + L   +L  + S     R+++ A    +     +  +L +E +L+   LL  
Sbjct: 352  AHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILE--RLLTW 409

Query: 1429 KGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEA 1488
            +G   + +  +R L L  LG++AL   K   ++   LL   LG L E  +  V A  + A
Sbjct: 410  QG---DPEPTVRWLGLLGLGHLALNRRKV--RHVSTLLPALLGALGEGDARLVGA-ALGA 463

Query: 1489 LTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKG 1548
            L ++L   R   V      +  +     D+  + +R  A  L G L R      +   +G
Sbjct: 464  LRRLLLRPR-APVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRG 522

Query: 1549 EVKK----AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMT 1604
             ++K    + +PL+L   DP  +AA++   T+ +C H + W  LE     +   + + ++
Sbjct: 523  PLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDSPEALS 582

Query: 1605 VFQTTMCSILTRKKPAVLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLD 1664
                 +C  L ++ P  +  FL +T  Y+++    +R AA  L G ++   S   + +  
Sbjct: 583  ----HLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVNQDL 638

Query: 1665 FPALRNSLQELQLDPDPGVRRAA 1687
              +L   L  LQ DP P V  AA
Sbjct: 639  LDSLFQDLGRLQSDPKPAVAAAA 661


>gi|187761381 maestro isoform d [Homo sapiens]
          Length = 262

 Score =  100 bits (248), Expect = 2e-20
 Identities = 58/164 (35%), Positives = 92/164 (56%), Gaps = 2/164 (1%)

Query: 1416 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1475
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 57   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 114

Query: 1476 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLA 1535
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+E++ LR  AF+LFG+LA
Sbjct: 115  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLA 174

Query: 1536 RVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQC 1579
               G   K FF  +VK+    L++H QD     A+AC  T   C
Sbjct: 175  AFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQAC 218


>gi|187761375 maestro isoform a [Homo sapiens]
          Length = 248

 Score =  100 bits (248), Expect = 2e-20
 Identities = 58/164 (35%), Positives = 92/164 (56%), Gaps = 2/164 (1%)

Query: 1416 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1475
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 43   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 100

Query: 1476 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLA 1535
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+E++ LR  AF+LFG+LA
Sbjct: 101  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLA 160

Query: 1536 RVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQC 1579
               G   K FF  +VK+    L++H QD     A+AC  T   C
Sbjct: 161  AFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQAC 204


>gi|47578111 hypothetical protein LOC140699 isoform 2 [Homo sapiens]
          Length = 608

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 86/426 (20%), Positives = 182/426 (42%), Gaps = 28/426 (6%)

Query: 832  PITAKIIHHYVSSCQDI--------CLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLT 883
            P++  I+   + S Q +          K+ F+  +  +++A+   +  + F  +    + 
Sbjct: 163  PLSEAIVEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIV 222

Query: 884  SIIVAVIKAEPTDNLVSPVRALAMEALSHLS--KLKPFYSTEENSELMDISIHSVISL-- 939
              +  +++ E   +L S +R      ++ LS   +     +E+ +EL  ++I S+I+L  
Sbjct: 223  HTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPS 282

Query: 940  --------QLPGEDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWILSE 991
                    ++      + + LY     +  ++++SL+ +    + L  +++ L  W+ S 
Sbjct: 283  VRTLTQIQEIMPNGTCNTECLYRQTFQAFSEMLQSLVVKDPHLENLDTIIKHLVPWLQSV 342

Query: 992  KEWEREKAVSLHLYLMWIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVL 1051
            K+ ERE+A +    ++        + + L+  + G +V L+A    D  ++    +   +
Sbjct: 343  KDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGI 402

Query: 1052 SSLLDLHASQTCSLWGPSKQKELE----KCKG--DLQSTDVEKIFCASSRIAKVVCMEFS 1105
             SLL +             Q+ L+    KC+   +L S+  +  +    RIA+V      
Sbjct: 403  HSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLD 462

Query: 1106 CDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVD 1165
             +E+   I    +    +     + S   +   L    +   +KV EI+  I   L ++ 
Sbjct: 463  SNELCQFIMTTFDTLKTLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIIS 522

Query: 1166 HPEVRRLLIDGILLLAHHHQET--ILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHS 1223
             P VR+ +I+ + L     + T  +L+ LL  P+P   HLAEVW  +S  +P    +L  
Sbjct: 523  QPRVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWR 582

Query: 1224 LMGRLQ 1229
            L+ +LQ
Sbjct: 583  LLRKLQ 588


>gi|47578113 hypothetical protein LOC140699 isoform 3 [Homo sapiens]
          Length = 573

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 87/424 (20%), Positives = 176/424 (41%), Gaps = 59/424 (13%)

Query: 832  PITAKIIHHYVSSCQDI--------CLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLT 883
            P++  I+   + S Q +          K+ F+  +  +++A+   +  + F  +    + 
Sbjct: 163  PLSEAIVEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIV 222

Query: 884  SIIVAVIKAEPTDNLVSPVRALAMEALSHLS--KLKPFYSTEENSELMDISIHSVISLQL 941
              +  +++ E   +L S +R      ++ LS   +     +E+ +EL  ++I S+I+L  
Sbjct: 223  HTLNVLVQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLP- 281

Query: 942  PGEDNESIKTLYANALSSLEQLMES------LLQRQLDPKGLQEMVQLLEKWILSEKEWE 995
                  S++TL     + ++++M +       L RQ      Q   ++L+  ++ +   E
Sbjct: 282  ------SVRTL-----TQIQEIMPNGTCNTECLYRQT----FQAFSEMLQSLVVKDPHLE 326

Query: 996  REKAVSLHLYLMWIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMNVLSSLL 1055
                              T + + L+  + G +V L+A    D  ++    +   + SLL
Sbjct: 327  NL---------------DTIIKLPLRFQRLGHLVALMALLCGDPQEKVAEEAAEGIHSLL 371

Query: 1056 DLHASQTCSLWGPSKQKELE----KCKG--DLQSTDVEKIFCASSRIAKVVCMEFSCDEV 1109
             +             Q+ L+    KC+   +L S+  +  +    RIA+V       +E+
Sbjct: 372  HITLRLKYITHDKKDQQNLKRALTKCREFLELHSSAAKCFYNCPFRIAQVFEGFLDSNEL 431

Query: 1110 VSLIQKLCENTGAMNLQHD--KASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVDHP 1167
               I    +     NL+H   + S   +   L    +   +KV EI+  I   L ++  P
Sbjct: 432  CQFIMTTFDTL--KNLKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQP 489

Query: 1168 EVRRLLIDGILLLAHHHQET--ILTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLM 1225
             VR+ +I+ + L     + T  +L+ LL  P+P   HLAEVW  +S  +P    +L  L+
Sbjct: 490  RVRQQIINTVSLFISRPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLL 549

Query: 1226 GRLQ 1229
             +LQ
Sbjct: 550  RKLQ 553


>gi|187761379 maestro isoform c [Homo sapiens]
          Length = 210

 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 33/103 (32%), Positives = 58/103 (56%), Gaps = 2/103 (1%)

Query: 1416 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1475
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 57   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 114

Query: 1476 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDN 1518
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+
Sbjct: 115  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDD 157


>gi|187761377 maestro isoform b [Homo sapiens]
          Length = 196

 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 33/103 (32%), Positives = 58/103 (56%), Gaps = 2/103 (1%)

Query: 1416 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1475
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 43   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 100

Query: 1476 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDN 1518
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+
Sbjct: 101  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDD 143


>gi|117956387 hypothetical protein LOC80133 [Homo sapiens]
          Length = 573

 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 98/475 (20%), Positives = 184/475 (38%), Gaps = 73/475 (15%)

Query: 913  LSKLKPFYSTEENSELMDISIHSVISLQLPGEDNESIKT-LYANALSSLEQLMESLLQRQ 971
            L K+K   S+ E  E M+   H+++++       E+I T L +  L  L+ L E L+   
Sbjct: 79   LDKVKEMGSSYEYIEDMENLYHNILNIY------ENILTSLVSKDLYKLQILKEMLVWMS 132

Query: 972  LDPKGLQEMVQLLEKWILSEKEWEREKAVSLHLYLMWIYVHSTAVCIHLKLGQFGTMVGL 1031
             D   LQE + ++   +L     +  K           Y+   A C+ L   +   +   
Sbjct: 133  KDSSYLQERIMVIINKVLRFTVTKVRK-----------YISVDAPCLGLLAAELSLL--- 178

Query: 1032 IAPCTCDAHQRTRMASMNVLSSLLDLHASQTCSLWGPS--KQKELEKCKGDLQ------S 1083
               C+ +     + AS+ +   L             P+  K   L+    D++       
Sbjct: 179  ---CSHEDPSIVKQASLGMCHLLYIARCQNDIGTNKPTNGKSHSLQFPSSDVEFLPKEFQ 235

Query: 1084 TDVEKIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQMRA 1143
             D  KI   + R+ + +      D V SL+ KL        +  D AS+  + F L+  A
Sbjct: 236  QDESKI---AQRVGQTLLPPLLTDFVQSLLMKLSSPDD--KIASDAASI--LIFTLEFHA 288

Query: 1144 KELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPMESHL 1203
            +++   V++I+ AI   L   D+  ++ +++  I LL     + ++  L+  P+P +  L
Sbjct: 289  EKVT-MVSKIVDAIYRQL--CDNNCMKDVMLQVITLLTCTSPKKVIFQLMDYPVPADDTL 345

Query: 1204 AEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKA-----DIWRLAAVDPLMTLCT 1258
             ++W A       A  +L +++  L+ +        ++      DI  L  +     LCT
Sbjct: 346  IQMWKAACSQASVAPHVLKTILLILKGKPGEMEDTVTEGKRFSLDITNLMPLAACQALCT 405

Query: 1259 IHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMN-- 1316
                +        +  + P L+ TL+ Q+  +       P+LK   L     L   +N  
Sbjct: 406  ---FLPLGSYRKAVAQYFPQLLTTLMFQVFYN---SELKPILKDRALYAQDALRVLLNCS 459

Query: 1317 -LQRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQH 1370
             LQ+V I                 TL ++  WD L +   +  GV  +A+   ++
Sbjct: 460  GLQQVDI-----------------TLMKENFWDQLSEDLCYYHGVCFIAKTLSEY 497


>gi|21071077 dishevelled-associated activator of morphogenesis 1
           [Homo sapiens]
          Length = 1078

 Score = 35.4 bits (80), Expect = 0.48
 Identities = 23/102 (22%), Positives = 46/102 (45%), Gaps = 6/102 (5%)

Query: 426 ETNKEAVRVGTLNLIRAIVSADEPRMSIRAIYLAIRVVKNTISDTRSKVRMAILHIIGQL 485
           ET++  +    +  I+A+++  + R  + A   +I V+  ++S    K ++A+L I+G +
Sbjct: 171 ETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAV 230

Query: 486 ALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEE 527
            L      + G   K L   L    Y     R +    DL++
Sbjct: 231 CL------VPGGHKKVLQAMLHYQKYASERTRFQTLINDLDK 266


>gi|57634534 nucleoporin 205kDa [Homo sapiens]
          Length = 2012

 Score = 35.0 bits (79), Expect = 0.63
 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 26/122 (21%)

Query: 672 WEDKLIQFLRNSLK----KTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRALGFTLAT 727
           W+ K  + + NSLK      RG +W+L LS EL +    F    +E+G  Y+        
Sbjct: 136 WDGK--RCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQGLTYK-------- 185

Query: 728 GLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEERIQESEQ 787
                     +L L+ + D +N+F  E +    GL +    K V +++ +  + + ES  
Sbjct: 186 ----------VLTLVSQIDVNNEF--EKLQRERGLGSEKHRKEVSDLIKECRQSLAESLF 233

Query: 788 SW 789
           +W
Sbjct: 234 AW 235


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 8/72 (11%)

Query: 1456 KKVKQYRKVLLEKCLGPLR---EPVSNSVTAEGMEAL-TKILAELREGDVGSSFDAMSEQ 1511
            KK   Y + +LE  L PLR   E V   +  +G +++  K   E +  ++ S F    EQ
Sbjct: 134  KKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSEF----EQ 189

Query: 1512 CRIFFDNESELL 1523
             R+F  NE E++
Sbjct: 190  IRLFLQNEQEMI 201


>gi|100814339 coiled-coil domain containing 146 [Homo sapiens]
          Length = 955

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 73/316 (23%), Positives = 129/316 (40%), Gaps = 44/316 (13%)

Query: 255 METFCETVQFYLKHLEESVYPVMTEEEFALKVFPMYRYFVTVWLRHYNPEVKL------- 307
           +E   +T+   LK +E  V  ++ E+E  +K     R  + +  R +N  VKL       
Sbjct: 262 LEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRALLEIKEREHNQLVKLLELAREN 321

Query: 308 -GVIKSLKPMLGLLLPN---------DDL----REQVYDYIPLLLAE--YQGSLEVLFVT 351
                + + +L L L N         D+L    RE+  D+  L   E   + S + L  T
Sbjct: 322 EATSLTERGILDLNLRNSLIDKQNYHDELSRKQREKERDFRNLRKMELLLKVSWDALRQT 381

Query: 352 QVLRQILELSVTTNTPVPQMQLHTIFTELH--VQVCNKAPAQHQYSSQNLMEMVHCFVAL 409
           Q L Q L L +    P     L     ELH  V+V  +  AQ +  S+   ++V   +A 
Sbjct: 382 QALHQRLLLEMEA-IPKDDSTLSERRRELHKEVEVAKRNLAQQKIISEMESKLVEQQLAE 440

Query: 410 ARSYPKELMKFFFSQMETNKEAVRVGTLNLIRAI-VSADEPRMSIRAIYLAIRVVKNTIS 468
                KE         E  KE V    +NL+R   +  DE     +    A +   N + 
Sbjct: 441 ENKLLKE--------QENMKELV----VNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVK 488

Query: 469 DTRSKVRMAILHIIGQLALCGYQERIKGWGLKYLSVQLTLSTYKLTNRREKFYQRDLEER 528
           + ++K     +H   +   C    R++ +   Y +++   +  K  N   K +Q+  E +
Sbjct: 489 EMKAKDLEIRIH---KKKKCEIYRRLREFAKLYDTIRNERN--KFVNLLHKAHQKVNEIK 543

Query: 529 MVHKVTMDTVKIITSS 544
             HK++++ ++I+ +S
Sbjct: 544 ERHKMSLNELEILRNS 559


>gi|93102424 hypothetical protein LOC23116 [Homo sapiens]
          Length = 1720

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 3/102 (2%)

Query: 1600 DDKMTVFQTTMCSILTRKKPAVLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHY 1659
            D+K+ + Q  M   L   K     + L   + ++K+  SR+R    N   I +  + T+ 
Sbjct: 446  DNKLVIKQEYMKIFLKLMKEVGPQQVLCLLLEHLKHKHSRVREEVVN---ICICSLLTYP 502

Query: 1660 LKKLDFPALRNSLQELQLDPDPGVRRAALETLTVLDSCSQHG 1701
             +  D P L   L    +D    VR+AALE   VL S    G
Sbjct: 503  SEDFDLPKLSFDLAPALVDSKRRVRQAALEAFAVLASSMGSG 544


>gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens]
          Length = 659

 Score = 32.7 bits (73), Expect = 3.1
 Identities = 19/44 (43%), Positives = 27/44 (61%)

Query: 1416 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVK 1459
            +E +L+  A+ L  G  Q E+ ALRV  + AL NMA  A +K+K
Sbjct: 447  KEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIK 490


>gi|12083581 phosphoinositide-specific phospholipase C beta 1 isoform
            a [Homo sapiens]
          Length = 1216

 Score = 31.6 bits (70), Expect = 6.9
 Identities = 13/39 (33%), Positives = 25/39 (64%)

Query: 15   ICLIQKKTLRKELEEEMTEAITEAAVASSEEVSEERDDL 53
            IC  +KK L+K+++++  E ITEA      ++ EE+ ++
Sbjct: 1060 ICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEM 1098


>gi|33356544 phosphoinositide-specific phospholipase C beta 1 isoform
            b [Homo sapiens]
          Length = 1173

 Score = 31.6 bits (70), Expect = 6.9
 Identities = 13/39 (33%), Positives = 25/39 (64%)

Query: 15   ICLIQKKTLRKELEEEMTEAITEAAVASSEEVSEERDDL 53
            IC  +KK L+K+++++  E ITEA      ++ EE+ ++
Sbjct: 1060 ICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEM 1098


>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
           sapiens]
          Length = 769

 Score = 31.6 bits (70), Expect = 6.9
 Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 20/98 (20%)

Query: 647 MWELEIALLVRYLEEHTE------FTWD-QKAWEDKLIQFLRNSLKKTRGSSWSLRLSKE 699
           +W+L    LVR  + HT+       + D  K W   L   +R         SW LR  ++
Sbjct: 599 VWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVR---------SWDLREGRQ 649

Query: 700 LNNQIASFDSPSLEKGFLYRALGFTLATGLEASKVEVL 737
           L      F S     G  Y   G  LA G+E+S VEVL
Sbjct: 650 LQQH--DFTSQIFSLG--YCPTGEWLAVGMESSNVEVL 683


>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
           sapiens]
          Length = 760

 Score = 31.6 bits (70), Expect = 6.9
 Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 20/98 (20%)

Query: 647 MWELEIALLVRYLEEHTE------FTWD-QKAWEDKLIQFLRNSLKKTRGSSWSLRLSKE 699
           +W+L    LVR  + HT+       + D  K W   L   +R         SW LR  ++
Sbjct: 590 VWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVR---------SWDLREGRQ 640

Query: 700 LNNQIASFDSPSLEKGFLYRALGFTLATGLEASKVEVL 737
           L      F S     G  Y   G  LA G+E+S VEVL
Sbjct: 641 LQQH--DFTSQIFSLG--YCPTGEWLAVGMESSNVEVL 674


>gi|157384982 transducin-like enhancer protein 3 isoform a [Homo
           sapiens]
          Length = 772

 Score = 31.6 bits (70), Expect = 6.9
 Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 20/98 (20%)

Query: 647 MWELEIALLVRYLEEHTE------FTWD-QKAWEDKLIQFLRNSLKKTRGSSWSLRLSKE 699
           +W+L    LVR  + HT+       + D  K W   L   +R         SW LR  ++
Sbjct: 602 VWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVR---------SWDLREGRQ 652

Query: 700 LNNQIASFDSPSLEKGFLYRALGFTLATGLEASKVEVL 737
           L      F S     G  Y   G  LA G+E+S VEVL
Sbjct: 653 LQQH--DFTSQIFSLG--YCPTGEWLAVGMESSNVEVL 686


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,262,101
Number of Sequences: 37866
Number of extensions: 2489609
Number of successful extensions: 7079
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 6972
Number of HSP's gapped (non-prelim): 46
length of query: 1710
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1594
effective length of database: 13,855,062
effective search space: 22084968828
effective search space used: 22084968828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.