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Search of human proteins with 239047498
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
(703 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 1447 0.0
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 1347 0.0
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 1214 0.0
gi|37674210 slingshot 2 [Homo sapiens] 647 0.0
gi|239582767 slingshot homolog 3 [Homo sapiens] 427 e-119
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 105 1e-22
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 103 4e-22
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 102 9e-22
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 102 2e-21
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 102 2e-21
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 101 3e-21
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 100 4e-21
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 99 1e-20
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 99 1e-20
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 93 7e-19
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 93 7e-19
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 92 1e-18
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 90 6e-18
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 86 1e-16
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 86 1e-16
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 84 3e-16
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 84 6e-16
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 80 5e-15
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 80 5e-15
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 80 5e-15
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 75 2e-13
gi|51491914 dual specificity phosphatase and pro isomerase domai... 73 8e-13
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 73 1e-12
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 71 4e-12
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 68 3e-11
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 1447 bits (3746), Expect = 0.0
Identities = 703/703 (100%), Positives = 703/703 (100%)
Query: 1 MARARRAVVGSVRDVSTAATNLFYFTDFCIFLQPTHCFCCPEVSSSNYLSESFFMVKGAA 60
MARARRAVVGSVRDVSTAATNLFYFTDFCIFLQPTHCFCCPEVSSSNYLSESFFMVKGAA
Sbjct: 1 MARARRAVVGSVRDVSTAATNLFYFTDFCIFLQPTHCFCCPEVSSSNYLSESFFMVKGAA 60
Query: 61 LFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRLESAWADRVRYMV 120
LFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRLESAWADRVRYMV
Sbjct: 61 LFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRLESAWADRVRYMV 120
Query: 121 VVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDGGFSVSTAGRMHI 180
VVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDGGFSVSTAGRMHI
Sbjct: 121 VVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDGGFSVSTAGRMHI 180
Query: 181 FKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYESCISSEQSCINEWNAMQD 240
FKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYESCISSEQSCINEWNAMQD
Sbjct: 181 FKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYESCISSEQSCINEWNAMQD 240
Query: 241 LESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIRNELEKQMNCNLK 300
LESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIRNELEKQMNCNLK
Sbjct: 241 LESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIRNELEKQMNCNLK 300
Query: 301 ELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFF 360
ELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFF
Sbjct: 301 ELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFF 360
Query: 361 PGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAM 420
PGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAM
Sbjct: 361 PGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAM 420
Query: 421 KEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQP 480
KEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQP
Sbjct: 421 KEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQP 480
Query: 481 VDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCFRRLSDPLLPSPEDETGSL 540
VDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCFRRLSDPLLPSPEDETGSL
Sbjct: 481 VDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCFRRLSDPLLPSPEDETGSL 540
Query: 541 VHLEDPEREALLEEAAPPAEVHRPARQPQQGSGLCEKDVKKKLEFGSPKGRSGSLLQVEE 600
VHLEDPEREALLEEAAPPAEVHRPARQPQQGSGLCEKDVKKKLEFGSPKGRSGSLLQVEE
Sbjct: 541 VHLEDPEREALLEEAAPPAEVHRPARQPQQGSGLCEKDVKKKLEFGSPKGRSGSLLQVEE 600
Query: 601 TEREEGLGAGRWGQLPTQLDQNLLNSENLNNNSKRSCPNGMEVGRARPAGWHTPSLPSHS 660
TEREEGLGAGRWGQLPTQLDQNLLNSENLNNNSKRSCPNGMEVGRARPAGWHTPSLPSHS
Sbjct: 601 TEREEGLGAGRWGQLPTQLDQNLLNSENLNNNSKRSCPNGMEVGRARPAGWHTPSLPSHS 660
Query: 661 NWPTSASVVGTTGTRHHTQLIFFYCLLWAPSSHLQGPEGSFTG 703
NWPTSASVVGTTGTRHHTQLIFFYCLLWAPSSHLQGPEGSFTG
Sbjct: 661 NWPTSASVVGTTGTRHHTQLIFFYCLLWAPSSHLQGPEGSFTG 703
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 1347 bits (3487), Expect = 0.0
Identities = 655/655 (100%), Positives = 655/655 (100%)
Query: 49 LSESFFMVKGAALFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRL 108
LSESFFMVKGAALFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRL
Sbjct: 38 LSESFFMVKGAALFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRL 97
Query: 109 ESAWADRVRYMVVVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDG 168
ESAWADRVRYMVVVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDG
Sbjct: 98 ESAWADRVRYMVVVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDG 157
Query: 169 GFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYESCISSE 228
GFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYESCISSE
Sbjct: 158 GFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYESCISSE 217
Query: 229 QSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIR 288
QSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIR
Sbjct: 218 QSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIR 277
Query: 289 NELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDY 348
NELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDY
Sbjct: 278 NELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDY 337
Query: 349 ILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGV 408
ILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGV
Sbjct: 338 ILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGV 397
Query: 409 SRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKL 468
SRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKL
Sbjct: 398 SRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKL 457
Query: 469 WRQQTDSSLQQPVDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCFRRLSDP 528
WRQQTDSSLQQPVDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCFRRLSDP
Sbjct: 458 WRQQTDSSLQQPVDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCFRRLSDP 517
Query: 529 LLPSPEDETGSLVHLEDPEREALLEEAAPPAEVHRPARQPQQGSGLCEKDVKKKLEFGSP 588
LLPSPEDETGSLVHLEDPEREALLEEAAPPAEVHRPARQPQQGSGLCEKDVKKKLEFGSP
Sbjct: 518 LLPSPEDETGSLVHLEDPEREALLEEAAPPAEVHRPARQPQQGSGLCEKDVKKKLEFGSP 577
Query: 589 KGRSGSLLQVEETEREEGLGAGRWGQLPTQLDQNLLNSENLNNNSKRSCPNGMEVGRARP 648
KGRSGSLLQVEETEREEGLGAGRWGQLPTQLDQNLLNSENLNNNSKRSCPNGMEVGRARP
Sbjct: 578 KGRSGSLLQVEETEREEGLGAGRWGQLPTQLDQNLLNSENLNNNSKRSCPNGMEVGRARP 637
Query: 649 AGWHTPSLPSHSNWPTSASVVGTTGTRHHTQLIFFYCLLWAPSSHLQGPEGSFTG 703
AGWHTPSLPSHSNWPTSASVVGTTGTRHHTQLIFFYCLLWAPSSHLQGPEGSFTG
Sbjct: 638 AGWHTPSLPSHSNWPTSASVVGTTGTRHHTQLIFFYCLLWAPSSHLQGPEGSFTG 692
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 1214 bits (3141), Expect = 0.0
Identities = 594/594 (100%), Positives = 594/594 (100%)
Query: 49 LSESFFMVKGAALFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRL 108
LSESFFMVKGAALFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRL
Sbjct: 38 LSESFFMVKGAALFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRL 97
Query: 109 ESAWADRVRYMVVVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDG 168
ESAWADRVRYMVVVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDG
Sbjct: 98 ESAWADRVRYMVVVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDG 157
Query: 169 GFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYESCISSE 228
GFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYESCISSE
Sbjct: 158 GFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYESCISSE 217
Query: 229 QSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIR 288
QSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIR
Sbjct: 218 QSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIR 277
Query: 289 NELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDY 348
NELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDY
Sbjct: 278 NELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDY 337
Query: 349 ILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGV 408
ILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGV
Sbjct: 338 ILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGV 397
Query: 409 SRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKL 468
SRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKL
Sbjct: 398 SRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKL 457
Query: 469 WRQQTDSSLQQPVDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCFRRLSDP 528
WRQQTDSSLQQPVDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCFRRLSDP
Sbjct: 458 WRQQTDSSLQQPVDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCFRRLSDP 517
Query: 529 LLPSPEDETGSLVHLEDPEREALLEEAAPPAEVHRPARQPQQGSGLCEKDVKKKLEFGSP 588
LLPSPEDETGSLVHLEDPEREALLEEAAPPAEVHRPARQPQQGSGLCEKDVKKKLEFGSP
Sbjct: 518 LLPSPEDETGSLVHLEDPEREALLEEAAPPAEVHRPARQPQQGSGLCEKDVKKKLEFGSP 577
Query: 589 KGRSGSLLQVEETEREEGLGAGRWGQLPTQLDQNLLNSENLNNNSKRSCPNGME 642
KGRSGSLLQVEETEREEGLGAGRWGQLPTQLDQNLLNSENLNNNSKRSCPNGME
Sbjct: 578 KGRSGSLLQVEETEREEGLGAGRWGQLPTQLDQNLLNSENLNNNSKRSCPNGME 631
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 647 bits (1668), Expect = 0.0
Identities = 321/479 (67%), Positives = 378/479 (78%), Gaps = 3/479 (0%)
Query: 44 SSSNYLSESFFMVKGAALFLQQGSSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIK 103
S +SESF VKGAALFL +G+ R +KHAGDL QHLQ M LLR ED I+
Sbjct: 32 SQPRSISESFLTVKGAALFLPRGNGSSTPRISHRRNKHAGDLQQHLQAMFILLRPEDNIR 91
Query: 104 LAVRLESAWADRVRYMVVVYSSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIH 163
LAVRLES + +R RYMVVV ++GRQDTEE+I+LG+DFSS +S +CT+G+VL LWSDT IH
Sbjct: 92 LAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIH 151
Query: 164 LDGDGGFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGVALIWATYYES 223
LDGDGGFSVST R+HIFKPVSVQAMWSALQ LHKACEVAR HNY+PG + L W +YYES
Sbjct: 152 LDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARAHNYYPGSLFLTWVSYYES 211
Query: 224 CISSEQSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVT 283
I+S+QS +NEWNAMQD++S RPDSPALF D PTE ERTERLIK KLR IMM +DLEN+T
Sbjct: 212 HINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENIT 271
Query: 284 SKEIRNELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQG 343
SKEIR ELE QM CNL+E KEFIDNEM++ILGQMD P+ IF+H++LGSEWNASNLE+LQ
Sbjct: 272 SKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQN 331
Query: 344 SGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVH 403
GV YILNVTREIDNFFPG+F YHNIRVYDEE TDLLA+WN+ Y FI+KAK++ SKCLVH
Sbjct: 332 RGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVH 391
Query: 404 CKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQ 463
CKMGVSRSASTVIAYAMKE+GW L++AY+YVK++R++T+PN FMRQL EY+GIL ASKQ
Sbjct: 392 CKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQ 451
Query: 464 RHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTPESQLPFLDDAAQPGLGPPLPCCF 522
RHNKLWR +DS L + PG L + T Q+ + PP+P F
Sbjct: 452 RHNKLWRSHSDSDLSDHHEPICKPGLELNKKDITTSADQIA---EVKTMESHPPIPPVF 507
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 427 bits (1098), Expect = e-119
Identities = 230/489 (47%), Positives = 320/489 (65%), Gaps = 36/489 (7%)
Query: 51 ESFFMVKGAALFLQQG----------SSPQ----------------GQRSLQHPHKHAGD 84
+SF +++GA L LQ G S P GQ S Q P K +
Sbjct: 36 QSFAVLRGAVLGLQDGGDNDDAAEASSEPTEKAPSEEELHGDQTDFGQGS-QSPQKQE-E 93
Query: 85 LPQHLQVMINLLRCEDRIKLAVRLESAWADRVRYMVVVYSSGRQ--DTEENILLGVDFSS 142
QHL +M+ LLR +D I+LA +LE+ R+RY++VV + + +E +LLGVDF
Sbjct: 94 QRQHLHLMVQLLRPQDDIRLAAQLEAPRPPRLRYLLVVSTREGEGLSQDETVLLGVDFPD 153
Query: 143 KESKSCTIGMVLRLWSDTKIHLDGDGGFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEV 202
S SCT+G+VL LWSDT+++LDGDGGFSV++ G+ IFKP+S+Q MW+ LQVLH+ACE
Sbjct: 154 SSSPSCTLGLVLPLWSDTQVYLDGDGGFSVTSGGQSRIFKPISIQTMWATLQVLHQACEA 213
Query: 203 ARRHNYFPGGVALIWATYYESCISSEQSCINEWNAMQDLESTRPDSPALFVDKPTEGERT 262
A PGG AL WA++Y+ ++SEQSC+NEW AM DLES RP P+ +E E+
Sbjct: 214 ALGSGLVPGGSALTWASHYQERLNSEQSCLNEWTAMADLESLRP--PSAEPGGSSEQEQM 271
Query: 263 ERLIKAKLRSIMMSQDLENVTSKEIRNELEKQMNCNLKELKEFIDNEMLLILGQMDKPSL 322
E+ I+A+L ++ DLE+VTSKEIR LE ++ L++ ++FIDN+MLL++ Q D+ S
Sbjct: 272 EQAIRAELWKVLDVSDLESVTSKEIRQALELRLGLPLQQYRDFIDNQMLLLVAQRDRASR 331
Query: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAH 382
IF HLYLGSEWNA+NLEELQ + V +ILN+ REIDNF+P F YHN+R++DEE+ LL H
Sbjct: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
Query: 383 WNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITR 442
W E + FI A+ + LVHCKMGVSRSA+TV+AYAMK++ LE+A +V++ R I R
Sbjct: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
Query: 443 PNAGFMRQLSEYEGILDASKQRHNKLWRQQTD--SSLQQPVDDPAGPGDFLPETPDGTPE 500
PN GF+RQL Y+GIL AS+Q H +W Q+ S + P + + P LP P+G E
Sbjct: 452 PNPGFLRQLQIYQGILTASRQSH--VWEQKVGGVSPEEHPAPEVSTPFPPLPPEPEGGGE 509
Query: 501 SQLPFLDDA 509
++ ++++
Sbjct: 510 EKVVGMEES 518
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 105 bits (263), Expect = 1e-22
Identities = 54/136 (39%), Positives = 85/136 (62%)
Query: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 379
P I +L+LGS ++S+L+ LQ G+ +LNV+ N F GLF Y +I V D + ++
Sbjct: 173 PVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEI 232
Query: 380 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 439
A + EA FI+ K + + LVHC+ G+SRSA+ +AY M+ L++A+++VKQ+R
Sbjct: 233 SAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRG 292
Query: 440 ITRPNAGFMRQLSEYE 455
+ PN FM QL ++E
Sbjct: 293 VISPNFSFMGQLLQFE 308
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 103 bits (258), Expect = 4e-22
Identities = 69/183 (37%), Positives = 97/183 (53%), Gaps = 8/183 (4%)
Query: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETT 377
P I +LYLGS +++NLE L G+ YILNVT + NFF G F Y I + D +
Sbjct: 204 PVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQ 263
Query: 378 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 437
+L + EA FI++A + LVHC GVSRS + +AY M++ L AY+ VK+K
Sbjct: 264 NLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRK 323
Query: 438 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDG 497
+S PN FM QL ++E L ++RH+ ++Q +P P F T DG
Sbjct: 324 KSNISPNFNFMGQLLDFERSL-RLEERHS---QEQGSGGQASAASNP--PSFFTTPTSDG 377
Query: 498 TPE 500
E
Sbjct: 378 AFE 380
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 102 bits (255), Expect = 9e-22
Identities = 53/136 (38%), Positives = 79/136 (58%)
Query: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 379
P I LYLGS ++AS + L G+ ++NV+ N F G + Y +I V D D+
Sbjct: 174 PVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADI 233
Query: 380 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 439
+ +NEA FI+ K + VHC+ G+SRSA+ +AY M+ L++A+ +VKQ+RS
Sbjct: 234 SSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRS 293
Query: 440 ITRPNAGFMRQLSEYE 455
I PN FM QL ++E
Sbjct: 294 IISPNFSFMGQLLQFE 309
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 102 bits (253), Expect = 2e-21
Identities = 65/186 (34%), Positives = 94/186 (50%), Gaps = 15/186 (8%)
Query: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 379
P I LYLGS ++A+ + L G+ +LNV+ + N F G + Y I V D D+
Sbjct: 196 PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADI 255
Query: 380 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 439
+ + EA +I+ K + LVHC+ G+SRSA+ +AY M + LE+A+ +VKQ+RS
Sbjct: 256 SSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRS 315
Query: 440 ITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTP 499
I PN FM QL ++E Q +S P+GP +TP TP
Sbjct: 316 IISPNFSFMGQLLQFES--------------QVLATSCAAEAASPSGPLRERGKTP-ATP 360
Query: 500 ESQLPF 505
SQ F
Sbjct: 361 TSQFVF 366
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 102 bits (253), Expect = 2e-21
Identities = 65/186 (34%), Positives = 94/186 (50%), Gaps = 15/186 (8%)
Query: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 379
P I LYLGS ++A+ + L G+ +LNV+ + N F G + Y I V D D+
Sbjct: 105 PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADI 164
Query: 380 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 439
+ + EA +I+ K + LVHC+ G+SRSA+ +AY M + LE+A+ +VKQ+RS
Sbjct: 165 SSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRS 224
Query: 440 ITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTP 499
I PN FM QL ++E Q +S P+GP +TP TP
Sbjct: 225 IISPNFSFMGQLLQFES--------------QVLATSCAAEAASPSGPLRERGKTP-ATP 269
Query: 500 ESQLPF 505
SQ F
Sbjct: 270 TSQFVF 275
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 101 bits (251), Expect = 3e-21
Identities = 55/136 (40%), Positives = 78/136 (57%)
Query: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 379
P I LYLGS ++AS E L + +LNV+R Y I V D T D+
Sbjct: 179 PVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADI 238
Query: 380 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 439
+H+ EA FI+ + K LVHC+ G+SRS + +AY MK + L++A++Y+KQ+RS
Sbjct: 239 SSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRS 298
Query: 440 ITRPNAGFMRQLSEYE 455
+ PN GFM QL +YE
Sbjct: 299 MVSPNFGFMGQLLQYE 314
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 100 bits (250), Expect = 4e-21
Identities = 64/192 (33%), Positives = 98/192 (51%), Gaps = 8/192 (4%)
Query: 283 TSKEIRNELEKQMNCNLKELKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQ 342
+S +I ++L++ N + N Q P I LYLG +++NL+ L+
Sbjct: 176 SSSDIESDLDRDPNSATDSDGSPLSNS------QPSFPVEILPFLYLGCAKDSTNLDVLE 229
Query: 343 GSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKC 400
G+ YILNVT + N F G F Y I + D + +L + EA FI++A+ +
Sbjct: 230 EFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGV 289
Query: 401 LVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDA 460
LVHC G+SRS + +AY M++ + AY+ VK K+S PN FM QL ++E L
Sbjct: 290 LVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGL 349
Query: 461 SKQRHNKLWRQQ 472
S N++ QQ
Sbjct: 350 SSPCDNRVPAQQ 361
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 99.4 bits (246), Expect = 1e-20
Identities = 58/155 (37%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
Query: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETT 377
P I +LYLG +++NL+ L G+ YILNVT + N F G F Y I + D +
Sbjct: 245 PVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQ 304
Query: 378 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 437
+L + EA FI++A+ LVHC G+SRS + +AY M++ L AY++VK+K
Sbjct: 305 NLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRK 364
Query: 438 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQ 472
+S PN FM QL ++E L S N +Q
Sbjct: 365 KSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQ 399
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 99.0 bits (245), Expect = 1e-20
Identities = 53/135 (39%), Positives = 78/135 (57%), Gaps = 2/135 (1%)
Query: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREID--NFFPGLFAYHNIRVYDEETTDLL 380
I L+LG+E +A +L+ +Q + Y++NVT + ++ GLF Y + D +L
Sbjct: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLR 384
Query: 381 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 440
++ EA+ FI +A + L+HC+ GVSRSA+ VIAY MK + AY +VK KR I
Sbjct: 385 QYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPI 444
Query: 441 TRPNAGFMRQLSEYE 455
PN FM QL E+E
Sbjct: 445 ISPNLNFMGQLLEFE 459
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 93.2 bits (230), Expect = 7e-19
Identities = 56/150 (37%), Positives = 82/150 (54%), Gaps = 5/150 (3%)
Query: 327 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEA 386
L LGS+ A +L+ L+ + V +ILNV ++N F F Y +I + D T++L+++ E
Sbjct: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
Query: 387 YHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAG 446
+ FI +AKR LVHC GVSR+A+ VI + M A++ VK R PN+G
Sbjct: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
Query: 447 FMRQLSEYEGILDASKQRHNKLWRQQTDSS 476
FM QL Y+ + NK R Q +SS
Sbjct: 193 FMEQLRTYQ-----EGKESNKCDRIQENSS 217
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 93.2 bits (230), Expect = 7e-19
Identities = 67/204 (32%), Positives = 93/204 (45%), Gaps = 13/204 (6%)
Query: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFA---YHNIRVYDEETTDL 379
I HLYLGS+ + N + + +G+ Y+LN + P + + + D L
Sbjct: 164 ILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPK--PDFICESRFMRVPINDNYCEKL 221
Query: 380 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 439
L +++ FI+KAK + + +VHC G+SRSA+ IAY MK G + AY +VK +R
Sbjct: 222 LPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRP 281
Query: 440 ITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTP 499
PN F+ QL EYE L T S +P PA G LP P T
Sbjct: 282 SISPNFNFLGQLLEYERSLKLLAALQGD---PGTPSGTPEPPPSPAA-GAPLPRLPPPTS 337
Query: 500 ESQLPFLDDAAQPGLG----PPLP 519
ES A + GL PP P
Sbjct: 338 ESAATGNAAAREGGLSAGGEPPAP 361
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 92.4 bits (228), Expect = 1e-18
Identities = 55/133 (41%), Positives = 71/133 (53%)
Query: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAH 382
I L+LG ASN LQ G+ I+N T EI NF F Y + + D + +
Sbjct: 30 ITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLY 89
Query: 383 WNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITR 442
++ I+ R H LVHC GVSRSA+ IAY MK L +AYN+VK +R + R
Sbjct: 90 FDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIR 149
Query: 443 PNAGFMRQLSEYE 455
PN GF RQL +YE
Sbjct: 150 PNVGFWRQLIDYE 162
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 90.1 bits (222), Expect = 6e-18
Identities = 64/204 (31%), Positives = 95/204 (46%), Gaps = 23/204 (11%)
Query: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREID--NFFPGLFAYHNIRVYDEETT 377
P+ I +LYLG + + N E +Q +G+ Y+LN + +F P + + V D
Sbjct: 159 PTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESH-FLRVPVNDSFCE 217
Query: 378 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 437
+L +++ FI KAK ++ LVHC G+SRSA+ IAY MK L++AY +VK+K
Sbjct: 218 KILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEK 277
Query: 438 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDG 497
R PN F+ QL +YE K + QT +S GP L
Sbjct: 278 RPTISPNFNFLGQLLDYE-----------KKIKNQTGAS---------GPKSKLKLLHLE 317
Query: 498 TPESQLPFLDDAAQPGLGPPLPCC 521
P +P + + Q P P C
Sbjct: 318 KPNEPVPAVSEGGQKSETPLSPPC 341
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 85.9 bits (211), Expect = 1e-16
Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Query: 341 LQGSGVDYILNVTREID--NFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHS 398
+Q + Y++NVT + ++ GLF Y + D +L ++ EA+ FI +A +
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 399 KCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE 455
L+HC+ GVSRSA+ VIAY MK + AY +VK KR I PN FM QL E+E
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFE 117
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 85.9 bits (211), Expect = 1e-16
Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Query: 341 LQGSGVDYILNVTREID--NFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHS 398
+Q + Y++NVT + ++ GLF Y + D +L ++ EA+ FI +A +
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 399 KCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE 455
L+HC+ GVSRSA+ VIAY MK + AY +VK KR I PN FM QL E+E
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFE 117
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 84.3 bits (207), Expect = 3e-16
Identities = 52/134 (38%), Positives = 68/134 (50%)
Query: 327 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEA 386
L+LGS A E+L +GV +NV+R+ A + V+D+ DLLAH
Sbjct: 26 LFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPT 85
Query: 387 YHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAG 446
+ A R CLV+CK G SRSA+ AY M+ G L KA+ VK R + PN G
Sbjct: 86 CAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPG 145
Query: 447 FMRQLSEYEGILDA 460
F QL +YE L A
Sbjct: 146 FWSQLQKYEEALQA 159
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 83.6 bits (205), Expect = 6e-16
Identities = 52/135 (38%), Positives = 73/135 (54%), Gaps = 5/135 (3%)
Query: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAH 382
I LY+G+ +A + E+L + V +IL+V G+ Y I D + +L H
Sbjct: 8 ILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGV-KYLCIPAADSPSQNLTRH 66
Query: 383 WNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAM--KEFGWPLEKAYNYVKQKRSI 440
+ E+ FI++ + CLVHC GVSRS + VIAY M +FGW E A + V+ RS
Sbjct: 67 FKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGW--EDALHTVRAGRSC 124
Query: 441 TRPNAGFMRQLSEYE 455
PN GF RQL E+E
Sbjct: 125 ANPNVGFQRQLQEFE 139
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 80.5 bits (197), Expect = 5e-15
Identities = 52/142 (36%), Positives = 77/142 (54%), Gaps = 7/142 (4%)
Query: 323 IFDHLYLGSEWNA--SNLEELQGSGVDYILNVTREID-NF----FPGLFAYHNIRVYDEE 375
I L+LG +A S L LQ G+ +I+ + + I+ NF F LF Y + + D
Sbjct: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
Query: 376 TTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 435
+++ + FI+ + + K LVH G+SRSA+ VIAY M+ FG A+ YV+
Sbjct: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
Query: 436 QKRSITRPNAGFMRQLSEYEGI 457
++R PNAGF+ QL EYE I
Sbjct: 152 ERRFCINPNAGFVHQLQEYEAI 173
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 80.5 bits (197), Expect = 5e-15
Identities = 52/142 (36%), Positives = 77/142 (54%), Gaps = 7/142 (4%)
Query: 323 IFDHLYLGSEWNA--SNLEELQGSGVDYILNVTREID-NF----FPGLFAYHNIRVYDEE 375
I L+LG +A S L LQ G+ +I+ + + I+ NF F LF Y + + D
Sbjct: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
Query: 376 TTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 435
+++ + FI+ + + K LVH G+SRSA+ VIAY M+ FG A+ YV+
Sbjct: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
Query: 436 QKRSITRPNAGFMRQLSEYEGI 457
++R PNAGF+ QL EYE I
Sbjct: 152 ERRFCINPNAGFVHQLQEYEAI 173
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 80.5 bits (197), Expect = 5e-15
Identities = 52/142 (36%), Positives = 77/142 (54%), Gaps = 7/142 (4%)
Query: 323 IFDHLYLGSEWNA--SNLEELQGSGVDYILNVTREID-NF----FPGLFAYHNIRVYDEE 375
I L+LG +A S L LQ G+ +I+ + + I+ NF F LF Y + + D
Sbjct: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
Query: 376 TTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 435
+++ + FI+ + + K LVH G+SRSA+ VIAY M+ FG A+ YV+
Sbjct: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
Query: 436 QKRSITRPNAGFMRQLSEYEGI 457
++R PNAGF+ QL EYE I
Sbjct: 152 ERRFCINPNAGFVHQLQEYEAI 173
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 75.1 bits (183), Expect = 2e-13
Identities = 50/135 (37%), Positives = 72/135 (53%), Gaps = 7/135 (5%)
Query: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVT----REIDNFFPGL-FAYHNIRVYDEETT 377
++ LYLG + A+N EL+ G+ ++LN + R + GL Y + +D
Sbjct: 65 VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAF 124
Query: 378 DLLAHWNEAYHFINKA-KRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQ 436
D+ H+ A FI++A + K LVHC +GVSRSA+ V+AY M L +A VK
Sbjct: 125 DMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKD 184
Query: 437 KRSITRPNAGFMRQL 451
R I PN GF+RQL
Sbjct: 185 HRGII-PNRGFLRQL 198
>gi|51491914 dual specificity phosphatase and pro isomerase domain
containing 1 [Homo sapiens]
Length = 220
Score = 73.2 bits (178), Expect = 8e-13
Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 9/160 (5%)
Query: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGL-------FAYHNIRVYDEE 375
++ LY+G E A + LQ +G ++LN N G YH + D
Sbjct: 58 VWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLP 117
Query: 376 TTDLLAHWNEAYHFINKA-KRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYV 434
T DL + A FI++A +HSK LVHC MG SRSA+ V+AY M L A V
Sbjct: 118 TFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQV 177
Query: 435 KQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTD 474
+ R + PN GF++QL E + L ++R + ++ D
Sbjct: 178 AKNRCVL-PNRGFLKQLRELDKQLVQQRRRSQRQDGEEED 216
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 72.8 bits (177), Expect = 1e-12
Identities = 50/157 (31%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 327 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEA 386
LYLG+ +A +L++L + + +I+++ + Y I V D + H+ E
Sbjct: 12 LYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDI-TYLRIPVADTPEVPIKKHFKEC 70
Query: 387 YHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAG 446
+FI+ + N CLVHC G+SRS + V AY M G +K R I PN G
Sbjct: 71 INFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPG 130
Query: 447 FMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDD 483
F +QL E+ AS Q KL RQ + + P D
Sbjct: 131 FRQQLEEFGW---ASSQ---KLRRQLEERFGESPFRD 161
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 70.9 bits (172), Expect = 4e-12
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 321 SLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLL 380
S I LY+ + A+N L + + ++NV+ E+ N Y + V D + L
Sbjct: 21 SQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLC 80
Query: 381 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 440
++ I+ + + L+HC GVSRSA+ +AY MK L A+ + K R I
Sbjct: 81 DFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPI 140
Query: 441 TRPNAGFMRQLSEYE 455
RPN+GF QL YE
Sbjct: 141 IRPNSGFWEQLIHYE 155
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 67.8 bits (164), Expect = 3e-11
Identities = 44/135 (32%), Positives = 64/135 (47%)
Query: 321 SLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLL 380
S I L+L + A++ L + + I+N + E+ N F Y + V D + L
Sbjct: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLY 82
Query: 381 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 440
++ I+ + L+HC GVSRSAS +AY MK L A+ + K +R I
Sbjct: 83 DFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPI 142
Query: 441 TRPNAGFMRQLSEYE 455
RPN GF QL YE
Sbjct: 143 IRPNNGFWEQLINYE 157
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,908,701
Number of Sequences: 37866
Number of extensions: 1552704
Number of successful extensions: 5100
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 96
Number of HSP's that attempted gapping in prelim test: 4951
Number of HSP's gapped (non-prelim): 227
length of query: 703
length of database: 18,247,518
effective HSP length: 109
effective length of query: 594
effective length of database: 14,120,124
effective search space: 8387353656
effective search space used: 8387353656
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.