Guide to the Human Genome
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Search of human proteins with 238550198

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|238550198 synaptotagmin III [Homo sapiens]
         (590 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|238550198 synaptotagmin III [Homo sapiens]                        1206   0.0  
gi|238550196 synaptotagmin III [Homo sapiens]                        1206   0.0  
gi|14150054 synaptotagmin III [Homo sapiens]                         1206   0.0  
gi|28376627 synaptotagmin IX [Homo sapiens]                           457   e-129
gi|39752671 synaptotagmin X [Homo sapiens]                            450   e-126
gi|45504376 synaptotagmin VI [Homo sapiens]                           413   e-115
gi|211059429 synaptotagmin II [Homo sapiens]                          283   4e-76
gi|31543670 synaptotagmin II [Homo sapiens]                           283   4e-76
gi|209447073 synaptotagmin I [Homo sapiens]                           281   9e-76
gi|5032139 synaptotagmin I [Homo sapiens]                             281   9e-76
gi|209447070 synaptotagmin I [Homo sapiens]                           281   9e-76
gi|92859638 synaptotagmin V [Homo sapiens]                            271   2e-72
gi|38570146 synaptotagmin VII [Homo sapiens]                          231   1e-60
gi|216548478 synaptotagmin XI [Homo sapiens]                          211   1e-54
gi|24308219 synaptotagmin IV [Homo sapiens]                           198   1e-50
gi|40068038 B/K protein [Homo sapiens]                                184   2e-46
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            165   9e-41
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             165   9e-41
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                 165   1e-40
gi|94536846 synaptotagmin VIII [Homo sapiens]                         156   4e-38
gi|29366828 synaptotagmin XII [Homo sapiens]                          150   4e-36
gi|47078261 double C2-like domains, alpha [Homo sapiens]              147   2e-35
gi|31881667 synaptotagmin XV isoform b [Homo sapiens]                 144   2e-34
gi|6005997 double C2-like domains, beta [Homo sapiens]                143   4e-34
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      130   4e-30
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      130   4e-30
gi|14249614 synaptotagmin-like 1 [Homo sapiens]                       119   1e-26
gi|24308233 synaptotagmin XIII [Homo sapiens]                         115   1e-25
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]             112   1e-24
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]             112   1e-24

>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score = 1206 bits (3120), Expect = 0.0
 Identities = 590/590 (100%), Positives = 590/590 (100%)

Query: 1   MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60
           MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV
Sbjct: 1   MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60

Query: 61  TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120
           TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG
Sbjct: 61  TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120

Query: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180
           LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK
Sbjct: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180

Query: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240
           PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS
Sbjct: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240

Query: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300
           QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC
Sbjct: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300

Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
           GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360

Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420
           NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420

Query: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
           DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR
Sbjct: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480

Query: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
           RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540

Query: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590
           AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE
Sbjct: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score = 1206 bits (3120), Expect = 0.0
 Identities = 590/590 (100%), Positives = 590/590 (100%)

Query: 1   MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60
           MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV
Sbjct: 1   MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60

Query: 61  TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120
           TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG
Sbjct: 61  TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120

Query: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180
           LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK
Sbjct: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180

Query: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240
           PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS
Sbjct: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240

Query: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300
           QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC
Sbjct: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300

Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
           GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360

Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420
           NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420

Query: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
           DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR
Sbjct: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480

Query: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
           RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540

Query: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590
           AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE
Sbjct: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score = 1206 bits (3120), Expect = 0.0
 Identities = 590/590 (100%), Positives = 590/590 (100%)

Query: 1   MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60
           MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV
Sbjct: 1   MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60

Query: 61  TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120
           TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG
Sbjct: 61  TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120

Query: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180
           LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK
Sbjct: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180

Query: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240
           PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS
Sbjct: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240

Query: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300
           QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC
Sbjct: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300

Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
           GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360

Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420
           NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420

Query: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
           DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR
Sbjct: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480

Query: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
           RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540

Query: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590
           AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE
Sbjct: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  457 bits (1177), Expect = e-129
 Identities = 268/570 (47%), Positives = 346/570 (60%), Gaps = 89/570 (15%)

Query: 7   DDLCRRALILVSDLCARVRDADTNDRCQEF--NDRIRGYPRGPDADISVSLLSVIVTFCG 64
           D LC +AL L+++LCAR   A  +D CQ+F  + R R  PR  D DISVSLL+++VT CG
Sbjct: 6   DALCHQALQLLAELCAR--GALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACG 63

Query: 65  IVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGGH 124
           + L GVSLFVSWKLCWVPWR++                     GL  G   +        
Sbjct: 64  LALFGVSLFVSWKLCWVPWRER---------------------GLPSGSKDNNQ------ 96

Query: 125 PLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQT 184
                                 EP  L   DT      + + + +       + +K S T
Sbjct: 97  ----------------------EP--LNYMDTETNEQENSEDFLDPPTPCPDSSMKISHT 132

Query: 185 SPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDP 244
           SP++P     G                +  +QVT    + R+ ++ R L      S PD 
Sbjct: 133 SPDIPLSTQTGI-------QENCAHGVRVQRQVTEPTSSARHNSIRRQLN----LSNPDF 181

Query: 245 SSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTG---PGGRRSGGGPGSGEAGTGAPCG 301
           + ++            +E+   IG+IKPELY+        GRRS              CG
Sbjct: 182 NIQQLQK---------QEQLTGIGRIKPELYKQRSLDNDDGRRSNS----------KACG 222

Query: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
           +++F L+Y    +QL+V+I +A++LPAKD +G SDPYVKIYLLPDRK K QTKVHRKTLN
Sbjct: 223 KLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLN 282

Query: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
           PVF+E F F VP  +L  RKLHFSVYDFDRFSRHDLIGQVV+D+ L+LA+ P +  LW+D
Sbjct: 283 PVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKD 342

Query: 422 IVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRR 481
           I    ++  DLGEL FSLCYLPTAGRLT+TIIKA NLKAMD+TG SDPYVK SL+ +GRR
Sbjct: 343 IEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRR 402

Query: 482 LKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
           LKKRKTS K+NTLNP YNEA+VFDV PE+++ + LSIAV+DYD +GHNE+IGVC+VG + 
Sbjct: 403 LKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVG-NE 461

Query: 542 ADPHGREHWAEMLANPRKPVEHWHQLVEEK 571
           A+  GR+HW+EML+ PRKP+ HWH LVE++
Sbjct: 462 AERLGRDHWSEMLSYPRKPIAHWHSLVEKR 491


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  450 bits (1157), Expect = e-126
 Identities = 262/566 (46%), Positives = 343/566 (60%), Gaps = 72/566 (12%)

Query: 4   DYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIVTFC 63
           D  + LC++AL +V++LC         ++C     R RG   G   DISVSLL+V+V+FC
Sbjct: 7   DGVNSLCQKALHIVTELC--FAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVVVSFC 64

Query: 64  GIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGG 123
           G+ LL VSLFV WKLCW  W+ K        P+  ++                L   +  
Sbjct: 65  GLALLVVSLFVFWKLCWPCWKSK--------PVTSNITT--------------LPQSISS 102

Query: 124 HPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQ 183
            P                  E+ E        T E   +  +  P   A  +   +K S 
Sbjct: 103 AP-----------------TEVFE--------TEEKKEIKENEKPAVKA--IEPAIKISH 135

Query: 184 TSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPD 243
           TSP++P+E        L       +  A+  +Q+T    +TR+ +  R L +Q   S  D
Sbjct: 136 TSPDIPAEVQTALKEHL-------IKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSSVD 188

Query: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
            S    P      L  GE     IG+IKPELY+      ++S    G+        CG++
Sbjct: 189 FSMGTEP-----VLQRGETTTS-IGRIKPELYK------QKSVDSEGNQNEDVKI-CGKL 235

Query: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPV 363
           +F L+Y Y ++ LVV+I++ALDLPAKD  G SDPYVK+YLLPDRKKKFQT+VHRKTLNP+
Sbjct: 236 NFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPL 295

Query: 364 FNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIV 423
           F+ETFQF V   +L+ RKLHFSVYDFDRFSRHD+IG+V+LDNL E+++   +  +W+DI 
Sbjct: 296 FDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIH 355

Query: 424 EGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLK 483
              +E  DLGE+ FSLCYLPTAGR+T+T+IK  NLKAMD+TG SDPYVK SL+ EGRRLK
Sbjct: 356 CATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLK 415

Query: 484 KRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD 543
           KRKT+ KKNTLNP YNEA++FD+ PE+V+ V LSIAV+DYD +GHNEVIGVCR G D A+
Sbjct: 416 KRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLD-AE 474

Query: 544 PHGREHWAEMLANPRKPVEHWHQLVE 569
             GR+HW EMLA  RKP+ HWH L+E
Sbjct: 475 GLGRDHWNEMLAYHRKPITHWHPLLE 500


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  413 bits (1062), Expect = e-115
 Identities = 227/447 (50%), Positives = 292/447 (65%), Gaps = 38/447 (8%)

Query: 139 HPPFAELLEPGSLGG--SDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPSEGGAGS 196
           +PP   L  P   G       +PS L            + A VK S TSP++P+E     
Sbjct: 15  NPPLEALQSPSFRGNMADKLKDPSTLGF----------LEAAVKISHTSPDIPAE----- 59

Query: 197 GLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDPSSEERPPALPLP 256
             + +      +   +  +Q T  A +TR+ +  R L +Q   S  D  +E         
Sbjct: 60  --VQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNE--------- 108

Query: 257 LPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRISFALRYLYGSDQL 316
           LP   E+   IG+IKPELY+      ++S  G  +    T + CG+I+F+LRY Y ++ L
Sbjct: 109 LPPAAEQPTSIGRIKPELYK------QKSVDGEDAKSEATKS-CGKINFSLRYDYETETL 161

Query: 317 VVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAE 376
           +VRIL+A DLPAKD  G SDPYVKIYLLPDRK K QT+VHRKTLNP F+E F F VP  E
Sbjct: 162 IVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEE 221

Query: 377 LAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELN 436
           LA RKLH SV+DFDRFSRHD+IG+V+LDNL E ++   +  +W+DI    SE  DLGE+ 
Sbjct: 222 LADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIM 281

Query: 437 FSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNP 496
           FSLCYLPTAGRLT+T+IK  NLKAMD+TG+SDPYVK SL+ +GRRLKK+KT+IKKNTLNP
Sbjct: 282 FSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNP 341

Query: 497 TYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLAN 556
            YNEA++FD+ PE+++ V L I+V+DYD +GHNE+IGVCRVG   A+  GR+HW EMLA 
Sbjct: 342 VYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVG-ITAEGLGRDHWNEMLAY 400

Query: 557 PRKPVEHWHQLVEEKTVTSFTKGSKGL 583
           PRKP+ HWH LVE K   SF +G+  L
Sbjct: 401 PRKPIAHWHSLVEVK--KSFKEGNPRL 425


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  283 bits (723), Expect = 4e-76
 Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 7/297 (2%)

Query: 288 GPGSGEAGTGAP-CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD 346
           G G GE        G++ F+L Y + ++QL V +LQA +LPA D  G SDPYVK++LLPD
Sbjct: 127 GEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD 186

Query: 347 RKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDN 405
           +KKK++TKVHRKTLNP FNETF F VP  EL  + L  ++YDFDRFS+HD+IG+V V  N
Sbjct: 187 KKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246

Query: 406 LLELAEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464
            ++L  QP +   WRD+  G  E+ + LG++  SL Y+PTAG+LTV I++A NLK MD+ 
Sbjct: 247 TVDLG-QPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVG 303

Query: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524
           G SDPYVK  L+  G+RLKK+KT++KK TLNP +NE+  F++  E ++ V + + V+DYD
Sbjct: 304 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363

Query: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSK 581
            +G NE IG   VG +A     R HW++MLANPR+P+  WH L  E+ V +    +K
Sbjct: 364 KLGKNEAIGKIFVGSNATGTELR-HWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  283 bits (723), Expect = 4e-76
 Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 7/297 (2%)

Query: 288 GPGSGEAGTGAP-CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD 346
           G G GE        G++ F+L Y + ++QL V +LQA +LPA D  G SDPYVK++LLPD
Sbjct: 127 GEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD 186

Query: 347 RKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDN 405
           +KKK++TKVHRKTLNP FNETF F VP  EL  + L  ++YDFDRFS+HD+IG+V V  N
Sbjct: 187 KKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246

Query: 406 LLELAEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464
            ++L  QP +   WRD+  G  E+ + LG++  SL Y+PTAG+LTV I++A NLK MD+ 
Sbjct: 247 TVDLG-QPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVG 303

Query: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524
           G SDPYVK  L+  G+RLKK+KT++KK TLNP +NE+  F++  E ++ V + + V+DYD
Sbjct: 304 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363

Query: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSK 581
            +G NE IG   VG +A     R HW++MLANPR+P+  WH L  E+ V +    +K
Sbjct: 364 KLGKNEAIGKIFVGSNATGTELR-HWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  281 bits (720), Expect = 9e-76
 Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)

Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
           G++ ++L Y + ++QL+V I+QA +LPA D  G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203

Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419
           NPVFNE F F VP +EL  + L  +VYDFDRFS+HD+IG+  V  N ++      +   W
Sbjct: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260

Query: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478
           RD+     E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK  L+  
Sbjct: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320

Query: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
           G+RLKK+KT+IKKNTLNP YNE+  F+V  E ++ V + + V+DYD IG N+ IG   VG
Sbjct: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380

Query: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573
            ++     R HW++MLANPR+P+  WH L  E+ V
Sbjct: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414



 Score = 79.7 bits (195), Expect = 7e-15
 Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)

Query: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381
           PA    G  D + K+      K+KF  ++H+  L P           L  L       +K
Sbjct: 29  PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82

Query: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431
             F   +  +         + + ++ +L +   D+ L  D  E G           E+  
Sbjct: 83  CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142

Query: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491
           LG+L +SL Y     +L V II+A+ L A+D+ G SDPYVK  L+ +  + KK +T + +
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200

Query: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550
            TLNP +NE   F V    +    L +AV D+D    +++IG  +V  +  D  H  E W
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 551 AEMLANPRKPVE 562
            ++ +  ++  E
Sbjct: 261 RDLQSAEKEEQE 272


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  281 bits (720), Expect = 9e-76
 Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)

Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
           G++ ++L Y + ++QL+V I+QA +LPA D  G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203

Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419
           NPVFNE F F VP +EL  + L  +VYDFDRFS+HD+IG+  V  N ++      +   W
Sbjct: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260

Query: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478
           RD+     E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK  L+  
Sbjct: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320

Query: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
           G+RLKK+KT+IKKNTLNP YNE+  F+V  E ++ V + + V+DYD IG N+ IG   VG
Sbjct: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380

Query: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573
            ++     R HW++MLANPR+P+  WH L  E+ V
Sbjct: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414



 Score = 79.7 bits (195), Expect = 7e-15
 Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)

Query: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381
           PA    G  D + K+      K+KF  ++H+  L P           L  L       +K
Sbjct: 29  PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82

Query: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431
             F   +  +         + + ++ +L +   D+ L  D  E G           E+  
Sbjct: 83  CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142

Query: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491
           LG+L +SL Y     +L V II+A+ L A+D+ G SDPYVK  L+ +  + KK +T + +
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200

Query: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550
            TLNP +NE   F V    +    L +AV D+D    +++IG  +V  +  D  H  E W
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 551 AEMLANPRKPVE 562
            ++ +  ++  E
Sbjct: 261 RDLQSAEKEEQE 272


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  281 bits (720), Expect = 9e-76
 Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)

Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
           G++ ++L Y + ++QL+V I+QA +LPA D  G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203

Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419
           NPVFNE F F VP +EL  + L  +VYDFDRFS+HD+IG+  V  N ++      +   W
Sbjct: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260

Query: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478
           RD+     E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK  L+  
Sbjct: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320

Query: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
           G+RLKK+KT+IKKNTLNP YNE+  F+V  E ++ V + + V+DYD IG N+ IG   VG
Sbjct: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380

Query: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573
            ++     R HW++MLANPR+P+  WH L  E+ V
Sbjct: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414



 Score = 79.7 bits (195), Expect = 7e-15
 Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)

Query: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381
           PA    G  D + K+      K+KF  ++H+  L P           L  L       +K
Sbjct: 29  PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82

Query: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431
             F   +  +         + + ++ +L +   D+ L  D  E G           E+  
Sbjct: 83  CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142

Query: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491
           LG+L +SL Y     +L V II+A+ L A+D+ G SDPYVK  L+ +  + KK +T + +
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200

Query: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550
            TLNP +NE   F V    +    L +AV D+D    +++IG  +V  +  D  H  E W
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260

Query: 551 AEMLANPRKPVE 562
            ++ +  ++  E
Sbjct: 261 RDLQSAEKEEQE 272


>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score =  271 bits (692), Expect = 2e-72
 Identities = 141/283 (49%), Positives = 193/283 (68%), Gaps = 9/283 (3%)

Query: 288 GPGSGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDR 347
           GPG  +       GR+ ++L Y + S QL+V ILQA+ L A D  G SDPYV++YLLPD+
Sbjct: 98  GPGQ-QVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDK 156

Query: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407
           +++++TKVHR+TLNP F ETF F VP  EL  R L  +VYDFDRFSR+D IG+V     +
Sbjct: 157 RRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEV----RV 212

Query: 408 ELAEQPPDRPL--WRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464
            ++     RP+  WR++     E+ + LG++ FSL Y+PTAG+LTV +++A NLK MD+ 
Sbjct: 213 PMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVG 272

Query: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524
           G SDPYVK  L+  G++++K+KT+IKKNTLNP YNEA  F+V  + V+ V + + V+DYD
Sbjct: 273 GLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYD 332

Query: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567
            +G NE IG   VG  AA   G  HWA+MLANPR+P+  WH L
Sbjct: 333 KLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPIAQWHSL 374


>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  231 bits (589), Expect = 1e-60
 Identities = 127/286 (44%), Positives = 175/286 (61%), Gaps = 11/286 (3%)

Query: 289 PGSGEAGTGAPC-----GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYL 343
           PGS E      C     GRI F++ Y +    L V+I++A +LPAKD +G SDP+VKIYL
Sbjct: 120 PGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYL 179

Query: 344 LPDRKKKFQTKVHRKTLNPVFNETFQFS-VPLAELAQRKLHFSVYDFDRFSRHDLIGQVV 402
           LPD+K K +TKV RK LNP +NETF F   P  ++ QR L+  V D+DRFSR+D IG+V 
Sbjct: 180 LPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVS 239

Query: 403 LD-NLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAM 461
           +  N ++L +    +  W+D+          GEL  SLCY P+A  + V IIKA NLKAM
Sbjct: 240 IPLNKVDLTQM---QTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAM 296

Query: 462 DLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVV 521
           D+ G SDPYVK  L+ + +R++K+KT   K  LNP +NE+  FD+  E +    + I V+
Sbjct: 297 DIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVM 356

Query: 522 DYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567
           D D +  N+VIG   +   +  P   +HW +M+A PR+PV  WHQL
Sbjct: 357 DKDKLSRNDVIGKIYLSWKSG-PGEVKHWKDMIARPRQPVAQWHQL 401


>gi|216548478 synaptotagmin XI [Homo sapiens]
          Length = 431

 Score =  211 bits (538), Expect = 1e-54
 Identities = 128/333 (38%), Positives = 186/333 (55%), Gaps = 22/333 (6%)

Query: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
           PSS      LP+ +  GEE    I  + P         G      P S E       G +
Sbjct: 113 PSSGSCIDQLPIKMDYGEELRSPITSLTP---------GESKTTSPSSPEEDV--MLGSL 161

Query: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPDRKKKFQTKVHRKTLNP 362
           +F++ Y +    LVV I +A  LP  D     SDPY+K+ +LPD++ + +T+V RKTL+P
Sbjct: 162 TFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDP 221

Query: 363 VFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDR---PL 418
           VF+ETF F  +P ++L    LHF V  FDRFSR D+IG+V    ++ LA   P      L
Sbjct: 222 VFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEV----MVPLAGVDPSTGKVQL 277

Query: 419 WRDIVEGGSEKA-DLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFS-DPYVKASLI 476
            RDI++   +K    GEL  SL Y P A R+TV ++KA +L  MD+TG S +PYVK ++ 
Sbjct: 278 TRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVY 337

Query: 477 SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCR 536
              +R+ K+KT +KK TLNP +NE+ ++D+  + + ++ +   V+D+D    NEV+G   
Sbjct: 338 YGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLI 397

Query: 537 VGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
           +G  +    G EHW E+  +PRKPV  WH L E
Sbjct: 398 LGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430


>gi|24308219 synaptotagmin IV [Homo sapiens]
          Length = 425

 Score =  198 bits (503), Expect = 1e-50
 Identities = 111/273 (40%), Positives = 166/273 (60%), Gaps = 7/273 (2%)

Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPDRKKKFQTKVHRKT 359
           G + F+L Y +     VV I +A  LPA D     SDPY+K+ +LP++K K +T+V RKT
Sbjct: 155 GTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKT 214

Query: 360 LNPVFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRP 417
           L+P F+ETF F  +P  ++ +  LHF++  FDRFSR D+IG+V++  + +EL+E      
Sbjct: 215 LDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGK--ML 272

Query: 418 LWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLI 476
           + R+I++    K+   GEL  SLCY  T   LTV ++KA +L   D++G SDPYVK +L 
Sbjct: 273 MNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLY 332

Query: 477 SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCR 536
              +R+ K+KT +KK T N  +NE  VFD+  E +E++ +   V+D +    NEVIG   
Sbjct: 333 HAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLV 392

Query: 537 VGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
           +G  AA+  G EHW E+   PR+ +  WH L +
Sbjct: 393 LGA-AAEGTGGEHWKEICDYPRRQIAKWHVLCD 424



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 4/104 (3%)

Query: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGF-SDPYVKASLISEGRRLKKRKTSIK 490
           LG L FSL Y        V I +A  L AMD     SDPY+K +++ E +   K KT + 
Sbjct: 154 LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKH--KVKTRVL 211

Query: 491 KNTLNPTYNEALVFDVAP-ESVENVGLSIAVVDYDCIGHNEVIG 533
           + TL+P ++E   F   P   ++ + L   ++ +D    +++IG
Sbjct: 212 RKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIG 255


>gi|40068038 B/K protein [Homo sapiens]
          Length = 474

 Score =  184 bits (468), Expect = 2e-46
 Identities = 105/274 (38%), Positives = 152/274 (55%), Gaps = 9/274 (3%)

Query: 301 GRISFALRYLYGSDQLVVRILQALDLP-------AKDSNGFSDPYVKIYLLPDRKKKFQT 353
           G + F+ +Y    + L VR+++A DLP       ++     S+PYVKI LLPD+K   QT
Sbjct: 186 GMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQT 245

Query: 354 KVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQP 413
            V RKT  PVF E + F +P  E  +R L  +V DFD+FSRH +IG+V +  L E+ +  
Sbjct: 246 GVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP-LCEV-DLV 303

Query: 414 PDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA 473
                W+ ++     + +LGEL  SL YLP+AGRL V +I+A  L   D++  SDP+VK 
Sbjct: 304 KGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKI 363

Query: 474 SLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIG 533
            L+   + +K +KTS  + T++P YNE+  F V  E +EN  L   V  ++    N+ IG
Sbjct: 364 QLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIG 423

Query: 534 VCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567
              +G  ++ P    HW  ML   R  VE WH L
Sbjct: 424 RIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 9/133 (6%)

Query: 429 KADLGELNFSLCYLPTAGRLTVTIIKASNLK-------AMDLTGFSDPYVKASLISEGRR 481
           K  LG L+FS  Y      LTV +I+A +L        +      S+PYVK  L+ + + 
Sbjct: 182 KYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKN 241

Query: 482 LKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
            K  +T +K+ T  P + E   F++     +   L + VVD+D    + VIG   V    
Sbjct: 242 SK--QTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCE 299

Query: 542 ADPHGREHWAEML 554
            D     HW + L
Sbjct: 300 VDLVKGGHWWKAL 312


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  165 bits (418), Expect = 9e-41
 Identities = 152/510 (29%), Positives = 212/510 (41%), Gaps = 74/510 (14%)

Query: 130 PHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELP 189
           P H A A       +   PG   G D P  +    +  P    A+ A     S+ S    
Sbjct: 194 PKHPARAPARGDSEDRRGPGQKTGPD-PASAPGRGNYGPPVRRASEARMSSSSRDSESWD 252

Query: 190 SEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLT-SQPDPSS-- 246
             GGAG        S  GL  A S Q       + + PA P+P    T   S+P P    
Sbjct: 253 HSGGAGDS----SRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAG 308

Query: 247 ---EERPPALP----LPLPGGEEKA------KLIGQIKPELYQGTGPGGRRSGGGPGSGE 293
              +++P   P       P  EE+         +G  +  +   +GP  + S   P    
Sbjct: 309 RFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAA 368

Query: 294 AGTGAP------------------CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFS 335
           A    P                   G + F+L Y   +  L   I++A  L   DSNG +
Sbjct: 369 ARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLA 428

Query: 336 DPYVKIYLLPDRKK--KFQTKVHRKTLNPVFNETFQFSVPLAELAQRK-LHFSVYDFDRF 392
           DPYVK++LLP   K  K +TK  R T NP++NET  +     E  QRK L  SV D D+F
Sbjct: 429 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 488

Query: 393 SRHDLIGQVVLDNLLELAEQPPDR------------PLWR---------------DIVEG 425
             ++ IG+        L +  P++            P+ R               + VE 
Sbjct: 489 GHNEFIGET----RFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER 544

Query: 426 GSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKR 485
             +  + G++  SL Y    G L V II+  +L AMD  G+SDP+VK  L  +  +  K 
Sbjct: 545 VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKH 604

Query: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPH 545
           KT IKK TLNP +NE   +D+    +    L I+V DYD    N+ IG C++G  A    
Sbjct: 605 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 664

Query: 546 GREHWAEMLANPRKPVEHWHQLVEEKTVTS 575
             +HW E L N  K +E WHQL  E  V+S
Sbjct: 665 -LKHWYECLKNKDKKIERWHQLQNENHVSS 693


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  165 bits (418), Expect = 9e-41
 Identities = 152/510 (29%), Positives = 212/510 (41%), Gaps = 74/510 (14%)

Query: 130 PHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELP 189
           P H A A       +   PG   G D P  +    +  P    A+ A     S+ S    
Sbjct: 190 PKHPARAPARGDSEDRRGPGQKTGPD-PASAPGRGNYGPPVRRASEARMSSSSRDSESWD 248

Query: 190 SEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLT-SQPDPSS-- 246
             GGAG        S  GL  A S Q       + + PA P+P    T   S+P P    
Sbjct: 249 HSGGAGDS----SRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAG 304

Query: 247 ---EERPPALP----LPLPGGEEKA------KLIGQIKPELYQGTGPGGRRSGGGPGSGE 293
              +++P   P       P  EE+         +G  +  +   +GP  + S   P    
Sbjct: 305 RFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAA 364

Query: 294 AGTGAP------------------CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFS 335
           A    P                   G + F+L Y   +  L   I++A  L   DSNG +
Sbjct: 365 ARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLA 424

Query: 336 DPYVKIYLLPDRKK--KFQTKVHRKTLNPVFNETFQFSVPLAELAQRK-LHFSVYDFDRF 392
           DPYVK++LLP   K  K +TK  R T NP++NET  +     E  QRK L  SV D D+F
Sbjct: 425 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 484

Query: 393 SRHDLIGQVVLDNLLELAEQPPDR------------PLWR---------------DIVEG 425
             ++ IG+        L +  P++            P+ R               + VE 
Sbjct: 485 GHNEFIGET----RFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER 540

Query: 426 GSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKR 485
             +  + G++  SL Y    G L V II+  +L AMD  G+SDP+VK  L  +  +  K 
Sbjct: 541 VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKH 600

Query: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPH 545
           KT IKK TLNP +NE   +D+    +    L I+V DYD    N+ IG C++G  A    
Sbjct: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660

Query: 546 GREHWAEMLANPRKPVEHWHQLVEEKTVTS 575
             +HW E L N  K +E WHQL  E  V+S
Sbjct: 661 -LKHWYECLKNKDKKIERWHQLQNENHVSS 689


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score =  165 bits (417), Expect = 1e-40
 Identities = 113/329 (34%), Positives = 165/329 (50%), Gaps = 19/329 (5%)

Query: 242 PDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCG 301
           P P+SE     LP    GG   A ++G I PELY+   P  +     P           G
Sbjct: 103 PCPASE----LLPHTSSGGLGDACMVGAINPELYKF--PEDKSETDFPDGC-------LG 149

Query: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
           R+ F++ Y   +++L+V +++A  L A        P VK+YLLPD ++  Q+K  RKT N
Sbjct: 150 RLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKTKRKTSN 207

Query: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
           P F+E F F V    + QR L FSVY  DR  +H L+GQV+     E       R +WRD
Sbjct: 208 PQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRD 267

Query: 422 I-VEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
           +  E     ++ G+L F L Y     RLTV +++A  L+  +  G    +VK SL++  +
Sbjct: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNK 327

Query: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
            +K +KTS    ++NP YNE   F      ++   LS+ VV       ++ +G   VGP 
Sbjct: 328 FVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGP- 386

Query: 541 AADPHGR--EHWAEMLANPRKPVEHWHQL 567
                GR  EHW EML+ P++ V+ WH L
Sbjct: 387 YMYTRGRELEHWDEMLSKPKELVKRWHAL 415


>gi|94536846 synaptotagmin VIII [Homo sapiens]
          Length = 401

 Score =  156 bits (395), Expect = 4e-38
 Identities = 102/282 (36%), Positives = 150/282 (53%), Gaps = 27/282 (9%)

Query: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTK 354
           G     GR+  +L + +GS ++ V + QA DL      G  DPY ++ +      + +TK
Sbjct: 113 GDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHETK 169

Query: 355 VHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQ-------VVLDNLL 407
           VHR TL PVF+ET  F +P AEL    L   +++F RFS H+ +G+       V L ++L
Sbjct: 170 VHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVL 229

Query: 408 E--LAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTG 465
           E      PP            ++   +GEL FSL Y+P++GRLTV +++A  L+     G
Sbjct: 230 EHWYLLGPP----------AATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PG 275

Query: 466 FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDC 525
            ++PYVK  L+   R+ KKRKT+ KK T  P +NEA  F V    V+NV L +AV D   
Sbjct: 276 LAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSL 335

Query: 526 IGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567
               E +G   +G  A+     +HWA+MLA+ R+P+   H L
Sbjct: 336 PLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376


>gi|29366828 synaptotagmin XII [Homo sapiens]
          Length = 421

 Score =  150 bits (378), Expect = 4e-36
 Identities = 89/277 (32%), Positives = 151/277 (54%), Gaps = 6/277 (2%)

Query: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK 350
           S   G     G++  ++ Y   S  L V ++Q  DL  ++   F   ++++ LLPD +  
Sbjct: 144 SNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIV 203

Query: 351 FQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLEL 409
             +++ R   +  F+E F   +    L ++ L FSV+  D   R+   G V L  ++L+L
Sbjct: 204 GISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDL 263

Query: 410 AEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSD 468
             QP    L+   ++  ++ AD +GE+  SL YLPTA RLTV ++KA NL   +    +D
Sbjct: 264 PLQPFSGWLY---LQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTAD 320

Query: 469 PYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGH 528
           P+VK  L+ +GR++ K+KT++K++  NP +NEA++F V    ++++ L + V +    G 
Sbjct: 321 PFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGR 380

Query: 529 NEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWH 565
            + +G   +GP A+   G  HW +MLA  R+PV  WH
Sbjct: 381 GDNVGHVIIGPSASG-MGTTHWNQMLATLRRPVSMWH 416


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score =  147 bits (372), Expect = 2e-35
 Identities = 106/342 (30%), Positives = 154/342 (45%), Gaps = 31/342 (9%)

Query: 259 GGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRISFALRYLYGSDQLVV 318
           GGE  A L+           G      G    S ++      G + F L Y   S  L  
Sbjct: 49  GGEAPAHLVPLALAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHC 108

Query: 319 RILQALDLPAKDSNGFSDPYVKIYLLPDRKK--KFQTKVHRKTLNPVFNETFQFS-VPLA 375
            IL+A  L   D NG +DPYVK++LLP   K  K +TK  R TLNPV+NE   +S +   
Sbjct: 109 SILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDD 168

Query: 376 ELAQRKLHFSVYDFDRFSRHDLIGQV-----------------VLDNLLELAEQPPDRPL 418
           ++  + L  +V D D+ S ++ IG++                  L+  + LA        
Sbjct: 169 DITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAA 228

Query: 419 WRDIV----------EGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSD 468
            R I           +G     + G +  SL Y      L V I++ ++L AMD+ G+SD
Sbjct: 229 LRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSD 288

Query: 469 PYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGH 528
           PYVK  L  +  +  K KT +KK TLNP +NE   +++   ++    L + V DYD    
Sbjct: 289 PYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKS 348

Query: 529 NEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEE 570
           N+ IG   +GP A     R+HW++ L  P   +E WH L  E
Sbjct: 349 NDFIGGVSLGPGARG-EARKHWSDCLQQPDAALERWHTLTSE 389


>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
          Length = 390

 Score =  144 bits (363), Expect = 2e-34
 Identities = 96/281 (34%), Positives = 141/281 (50%), Gaps = 16/281 (5%)

Query: 242 PDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCG 301
           P P+SE     LP    GG   A ++G I PELY+   P  +     P           G
Sbjct: 103 PCPASE----LLPHTSSGGLGDACMVGAINPELYKF--PEDKSETDFPDGC-------LG 149

Query: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
           R+ F++ Y   +++L+V +++A  L A        P VK+YLLPD ++  Q+K  RKT N
Sbjct: 150 RLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKTKRKTSN 207

Query: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
           P F+E F F V    + QR L FSVY  DR  +H L+GQV+     E       R +WRD
Sbjct: 208 PQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRD 267

Query: 422 I-VEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
           +  E     ++ G+L F L Y     RLTV +++A  L+  +  G    +VK SL++  +
Sbjct: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNK 327

Query: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVV 521
            +K +KTS    ++NP YNE   F      ++   LS+ VV
Sbjct: 328 FVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  143 bits (361), Expect = 4e-34
 Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 9/278 (3%)

Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKK--KFQTKVHRK 358
           G + F+L Y   ++ L   I +A  L   D NG +DPYVK++LLP   K  K +TK  R 
Sbjct: 128 GTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRN 187

Query: 359 TLNPVFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQ--VVLDNLLELAEQPPD 415
           TLNP +NET  +  +   ++ ++ L  SV D D+F  ++ IG+  V L  L     +  +
Sbjct: 188 TLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFN 247

Query: 416 RPLWRDIVEGGSEKADL---GELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVK 472
             L + +    +E   L   G +  SL Y      L V I++ ++L AMD  G+SDPYVK
Sbjct: 248 ICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVK 307

Query: 473 ASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVI 532
             L  +  +  K KT++KK TLNP +NE   +++    +    L + V DYD    N+ I
Sbjct: 308 TYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFI 367

Query: 533 GVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEE 570
           G   +G  A      +HW + L N  K +E WH L  E
Sbjct: 368 GGVVLGIHAKGER-LKHWFDCLKNKDKRIERWHTLTSE 404



 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 53/130 (40%), Positives = 67/130 (51%), Gaps = 4/130 (3%)

Query: 412 QPPDRPLWRDIVEGGSEKAD---LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSD 468
           +PP +P   +    G E  D   LG L+FSL Y      L  TI KA  LK MD  G +D
Sbjct: 104 RPPAKPPEDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLAD 163

Query: 469 PYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALV-FDVAPESVENVGLSIAVVDYDCIG 527
           PYVK  L+    +  K +T   +NTLNPT+NE L  + +  E +    L I+V D D   
Sbjct: 164 PYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFR 223

Query: 528 HNEVIGVCRV 537
           HNE IG  RV
Sbjct: 224 HNEFIGETRV 233


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  130 bits (326), Expect = 4e-30
 Identities = 94/284 (33%), Positives = 142/284 (50%), Gaps = 48/284 (16%)

Query: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK 349
           +G+ G     GRI+F+L+Y   +  LVV + +   L  A ++   S+PYVK YLLPD+ +
Sbjct: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407

Query: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV------ 401
             K +T + R T+NP+++ET ++ +P + LAQR L FSV+   RF R+  +G+       
Sbjct: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467

Query: 402 -----VLDNLLEL-----AEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTA------ 445
                 LD+ L L     AE P   P            +  GEL  SL Y+P +      
Sbjct: 468 WKLDKKLDHCLPLHGKISAESPTGLP------------SHKGELVVSLKYIPASKTPVGG 515

Query: 446 ----------GRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLN 495
                     G L V I +A NL A    G SD +VK  L+    +  KRKT + K TLN
Sbjct: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575

Query: 496 PTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
           P YN   V++ V  E ++++ L + V D + +  N+ +G  R+G
Sbjct: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 1/110 (0%)

Query: 433 GELNFSLCYLPTAGRLTVTIIKASNLKAMD-LTGFSDPYVKASLISEGRRLKKRKTSIKK 491
           G + FSL Y      L V + +   L   D     S+PYVK  L+ +  R  KRKTSIK+
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
           +T+NP Y+E L +++    +    L  +V  +   G N  +G   +  D+
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  130 bits (326), Expect = 4e-30
 Identities = 94/284 (33%), Positives = 142/284 (50%), Gaps = 48/284 (16%)

Query: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK 349
           +G+ G     GRI+F+L+Y   +  LVV + +   L  A ++   S+PYVK YLLPD+ +
Sbjct: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407

Query: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV------ 401
             K +T + R T+NP+++ET ++ +P + LAQR L FSV+   RF R+  +G+       
Sbjct: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467

Query: 402 -----VLDNLLEL-----AEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTA------ 445
                 LD+ L L     AE P   P            +  GEL  SL Y+P +      
Sbjct: 468 WKLDKKLDHCLPLHGKISAESPTGLP------------SHKGELVVSLKYIPASKTPVGG 515

Query: 446 ----------GRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLN 495
                     G L V I +A NL A    G SD +VK  L+    +  KRKT + K TLN
Sbjct: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575

Query: 496 PTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
           P YN   V++ V  E ++++ L + V D + +  N+ +G  R+G
Sbjct: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 1/110 (0%)

Query: 433 GELNFSLCYLPTAGRLTVTIIKASNLKAMD-LTGFSDPYVKASLISEGRRLKKRKTSIKK 491
           G + FSL Y      L V + +   L   D     S+PYVK  L+ +  R  KRKTSIK+
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
           +T+NP Y+E L +++    +    L  +V  +   G N  +G   +  D+
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467


>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
          Length = 550

 Score =  119 bits (297), Expect = 1e-26
 Identities = 118/459 (25%), Positives = 188/459 (40%), Gaps = 38/459 (8%)

Query: 131 HHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPS 190
           HH+AH       A +    S  G   P       D   EAA      G +P  T  E P 
Sbjct: 92  HHNAHFGSDLVRASMRRKKSTRGDQAP-----GHDREAEAAVKEKEEGPEPRLTIDEAPQ 146

Query: 191 E-------GGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPD 243
           E                    G G     + +    L P +     PRP   QT  +   
Sbjct: 147 ERLRETEASDPEEASQAQEDPGQGDQQVCAEEADPELEPASGGEQEPRPQQAQTKAASQI 206

Query: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
             + E  P    P P  +        +   L   T  G + S     SG+A      G +
Sbjct: 207 LENGEEAPG---PDPSLDRMLSSSSSVS-SLNSSTLSGSQMSL----SGDAEAVQVRGSV 258

Query: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPV 363
            FAL Y  G+ +L V ++Q   L A      SDPYVK YLLPD++ K +T V ++ LNPV
Sbjct: 259 HFALHYEPGAAELRVHVIQCQGLAAARRRR-SDPYVKSYLLPDKQSKRKTAVKKRNLNPV 317

Query: 364 FNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRPLWRDI 422
           FNET ++SVP AEL  R L  SV+  +   R+  +G+V +  +  +   +P   PL   +
Sbjct: 318 FNETLRYSVPQAELQGRVLSLSVWHRESLGRNIFLGEVEVPLDTWDWGSEPTWLPLQPRV 377

Query: 423 VEGGSEKADLGELNFSLCY---------LPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA 473
                +    G L  SL Y         LP +G L   + +A +L  +   G  D YV+ 
Sbjct: 378 PPSPDDLPSRGLLALSLKYVPAGSEGAGLPPSGELHFWVKEARDLLPL-RAGSLDTYVQC 436

Query: 474 SLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVI 532
            ++ +  +  +++T + + +L+P +N  +V+D   P  +      +++ D+  +  N  +
Sbjct: 437 FVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGALA-NRQL 495

Query: 533 GVCRVGPDAADPHGRE-HWAEMLANPRKPVEHWHQLVEE 570
           G  R+       +G +  W +     +   + W  L+E+
Sbjct: 496 GGTRLSLGTGSSYGLQVPWMDSTPEEK---QLWQALLEQ 531


>gi|24308233 synaptotagmin XIII [Homo sapiens]
          Length = 426

 Score =  115 bits (287), Expect = 1e-25
 Identities = 101/351 (28%), Positives = 164/351 (46%), Gaps = 24/351 (6%)

Query: 230 PRP-LTQQTLTSQPDPS--SEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRS- 285
           PRP +T   + +  D S  S E P A   P P  + + K   Q+  EL+     G     
Sbjct: 85  PRPAVTAPEVINYADYSLRSTEEPTAPASPQPPNDSRLKR--QVTEELFILPQNGVVEDV 142

Query: 286 ----GGGPGSGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKI 341
                  P    +   AP  ++ + L Y     +L V  L+A+     + +G  D YV+ 
Sbjct: 143 CVMETWNPEKAASWNQAP--KLHYCLDYDCQKAELFVTRLEAV---TSNHDGGCDCYVQG 197

Query: 342 YLLPDRKK-KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQ 400
            +       + QT + ++ L+  + E     +   EL    L  ++   DRFSRH + G+
Sbjct: 198 SVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGE 257

Query: 401 VVLDNLLELAEQPPDRPLWRDIVEGGSE-KADLGELNFSLCYLPTAGRLTVTIIKASNL- 458
           + L   L+    P     W ++     E  A  GE+  S+ YLP A RL V +IKA NL 
Sbjct: 258 LRLG--LDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLH 315

Query: 459 --KAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGL 516
             ++ +L G  D  VK +L  + R+LKK++T   K+ +NP +NE ++F++  + ++   +
Sbjct: 316 SNQSKELLG-KDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSV 374

Query: 517 SIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567
            + V+  D  G +  +G C +G   +    R HW EML NPR+ +  WHQL
Sbjct: 375 ELEVLGQDDSGQSCALGHCSLGLHTSGSE-RSHWEEMLKNPRRQIAMWHQL 424


>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score =  112 bits (280), Expect = 1e-24
 Identities = 101/358 (28%), Positives = 166/358 (46%), Gaps = 35/358 (9%)

Query: 231 RPLTQQTLTSQPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPG 290
           +P+T + +   P  S+    P  P   P   +K K + +  P   Q    G   S     
Sbjct: 545 KPVTNECV---PRISTVPTQPDNPFSHP---DKLKRMSKSVPAFLQDEVSGSVMS---VY 595

Query: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 596 SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 655

Query: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 656 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 713

Query: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 714 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 773

Query: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 774 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 832

Query: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 833 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 887


>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
          Length = 376

 Score =  112 bits (279), Expect = 1e-24
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 62  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 121

Query: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 122 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 179

Query: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 239

Query: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 240 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 298

Query: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 299 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 353


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.137    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,014,915
Number of Sequences: 37866
Number of extensions: 1685335
Number of successful extensions: 12520
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 582
Number of HSP's that attempted gapping in prelim test: 9666
Number of HSP's gapped (non-prelim): 2686
length of query: 590
length of database: 18,247,518
effective HSP length: 108
effective length of query: 482
effective length of database: 14,157,990
effective search space: 6824151180
effective search space used: 6824151180
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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