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Search of human proteins with 238550198
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238550198 synaptotagmin III [Homo sapiens]
(590 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238550198 synaptotagmin III [Homo sapiens] 1206 0.0
gi|238550196 synaptotagmin III [Homo sapiens] 1206 0.0
gi|14150054 synaptotagmin III [Homo sapiens] 1206 0.0
gi|28376627 synaptotagmin IX [Homo sapiens] 457 e-129
gi|39752671 synaptotagmin X [Homo sapiens] 450 e-126
gi|45504376 synaptotagmin VI [Homo sapiens] 413 e-115
gi|211059429 synaptotagmin II [Homo sapiens] 283 4e-76
gi|31543670 synaptotagmin II [Homo sapiens] 283 4e-76
gi|209447073 synaptotagmin I [Homo sapiens] 281 9e-76
gi|5032139 synaptotagmin I [Homo sapiens] 281 9e-76
gi|209447070 synaptotagmin I [Homo sapiens] 281 9e-76
gi|92859638 synaptotagmin V [Homo sapiens] 271 2e-72
gi|38570146 synaptotagmin VII [Homo sapiens] 231 1e-60
gi|216548478 synaptotagmin XI [Homo sapiens] 211 1e-54
gi|24308219 synaptotagmin IV [Homo sapiens] 198 1e-50
gi|40068038 B/K protein [Homo sapiens] 184 2e-46
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 165 9e-41
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 165 9e-41
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 165 1e-40
gi|94536846 synaptotagmin VIII [Homo sapiens] 156 4e-38
gi|29366828 synaptotagmin XII [Homo sapiens] 150 4e-36
gi|47078261 double C2-like domains, alpha [Homo sapiens] 147 2e-35
gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 144 2e-34
gi|6005997 double C2-like domains, beta [Homo sapiens] 143 4e-34
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 130 4e-30
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 130 4e-30
gi|14249614 synaptotagmin-like 1 [Homo sapiens] 119 1e-26
gi|24308233 synaptotagmin XIII [Homo sapiens] 115 1e-25
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] 112 1e-24
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens] 112 1e-24
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 1206 bits (3120), Expect = 0.0
Identities = 590/590 (100%), Positives = 590/590 (100%)
Query: 1 MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60
MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV
Sbjct: 1 MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60
Query: 61 TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120
TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG
Sbjct: 61 TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120
Query: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180
LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK
Sbjct: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180
Query: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240
PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS
Sbjct: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240
Query: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300
QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC
Sbjct: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300
Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420
NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420
Query: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR
Sbjct: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
Query: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
Query: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590
AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE
Sbjct: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 1206 bits (3120), Expect = 0.0
Identities = 590/590 (100%), Positives = 590/590 (100%)
Query: 1 MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60
MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV
Sbjct: 1 MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60
Query: 61 TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120
TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG
Sbjct: 61 TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120
Query: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180
LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK
Sbjct: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180
Query: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240
PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS
Sbjct: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240
Query: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300
QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC
Sbjct: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300
Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420
NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420
Query: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR
Sbjct: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
Query: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
Query: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590
AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE
Sbjct: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 1206 bits (3120), Expect = 0.0
Identities = 590/590 (100%), Positives = 590/590 (100%)
Query: 1 MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60
MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV
Sbjct: 1 MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIV 60
Query: 61 TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120
TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG
Sbjct: 61 TFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAG 120
Query: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180
LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK
Sbjct: 121 LGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVK 180
Query: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240
PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS
Sbjct: 181 PSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTS 240
Query: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300
QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC
Sbjct: 241 QPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPC 300
Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420
NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWR 420
Query: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR
Sbjct: 421 DIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
Query: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
Query: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590
AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE
Sbjct: 541 AADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 590
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 457 bits (1177), Expect = e-129
Identities = 268/570 (47%), Positives = 346/570 (60%), Gaps = 89/570 (15%)
Query: 7 DDLCRRALILVSDLCARVRDADTNDRCQEF--NDRIRGYPRGPDADISVSLLSVIVTFCG 64
D LC +AL L+++LCAR A +D CQ+F + R R PR D DISVSLL+++VT CG
Sbjct: 6 DALCHQALQLLAELCAR--GALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACG 63
Query: 65 IVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGGH 124
+ L GVSLFVSWKLCWVPWR++ GL G +
Sbjct: 64 LALFGVSLFVSWKLCWVPWRER---------------------GLPSGSKDNNQ------ 96
Query: 125 PLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQT 184
EP L DT + + + + + +K S T
Sbjct: 97 ----------------------EP--LNYMDTETNEQENSEDFLDPPTPCPDSSMKISHT 132
Query: 185 SPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDP 244
SP++P G + +QVT + R+ ++ R L S PD
Sbjct: 133 SPDIPLSTQTGI-------QENCAHGVRVQRQVTEPTSSARHNSIRRQLN----LSNPDF 181
Query: 245 SSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTG---PGGRRSGGGPGSGEAGTGAPCG 301
+ ++ +E+ IG+IKPELY+ GRRS CG
Sbjct: 182 NIQQLQK---------QEQLTGIGRIKPELYKQRSLDNDDGRRSNS----------KACG 222
Query: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
+++F L+Y +QL+V+I +A++LPAKD +G SDPYVKIYLLPDRK K QTKVHRKTLN
Sbjct: 223 KLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLN 282
Query: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
PVF+E F F VP +L RKLHFSVYDFDRFSRHDLIGQVV+D+ L+LA+ P + LW+D
Sbjct: 283 PVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKD 342
Query: 422 IVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRR 481
I ++ DLGEL FSLCYLPTAGRLT+TIIKA NLKAMD+TG SDPYVK SL+ +GRR
Sbjct: 343 IEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRR 402
Query: 482 LKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
LKKRKTS K+NTLNP YNEA+VFDV PE+++ + LSIAV+DYD +GHNE+IGVC+VG +
Sbjct: 403 LKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVG-NE 461
Query: 542 ADPHGREHWAEMLANPRKPVEHWHQLVEEK 571
A+ GR+HW+EML+ PRKP+ HWH LVE++
Sbjct: 462 AERLGRDHWSEMLSYPRKPIAHWHSLVEKR 491
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 450 bits (1157), Expect = e-126
Identities = 262/566 (46%), Positives = 343/566 (60%), Gaps = 72/566 (12%)
Query: 4 DYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIVTFC 63
D + LC++AL +V++LC ++C R RG G DISVSLL+V+V+FC
Sbjct: 7 DGVNSLCQKALHIVTELC--FAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVVVSFC 64
Query: 64 GIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGG 123
G+ LL VSLFV WKLCW W+ K P+ ++ L +
Sbjct: 65 GLALLVVSLFVFWKLCWPCWKSK--------PVTSNITT--------------LPQSISS 102
Query: 124 HPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQ 183
P E+ E T E + + P A + +K S
Sbjct: 103 AP-----------------TEVFE--------TEEKKEIKENEKPAVKA--IEPAIKISH 135
Query: 184 TSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPD 243
TSP++P+E L + A+ +Q+T +TR+ + R L +Q S D
Sbjct: 136 TSPDIPAEVQTALKEHL-------IKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSSVD 188
Query: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
S P L GE IG+IKPELY+ ++S G+ CG++
Sbjct: 189 FSMGTEP-----VLQRGETTTS-IGRIKPELYK------QKSVDSEGNQNEDVKI-CGKL 235
Query: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPV 363
+F L+Y Y ++ LVV+I++ALDLPAKD G SDPYVK+YLLPDRKKKFQT+VHRKTLNP+
Sbjct: 236 NFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPL 295
Query: 364 FNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIV 423
F+ETFQF V +L+ RKLHFSVYDFDRFSRHD+IG+V+LDNL E+++ + +W+DI
Sbjct: 296 FDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIH 355
Query: 424 EGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLK 483
+E DLGE+ FSLCYLPTAGR+T+T+IK NLKAMD+TG SDPYVK SL+ EGRRLK
Sbjct: 356 CATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLK 415
Query: 484 KRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD 543
KRKT+ KKNTLNP YNEA++FD+ PE+V+ V LSIAV+DYD +GHNEVIGVCR G D A+
Sbjct: 416 KRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLD-AE 474
Query: 544 PHGREHWAEMLANPRKPVEHWHQLVE 569
GR+HW EMLA RKP+ HWH L+E
Sbjct: 475 GLGRDHWNEMLAYHRKPITHWHPLLE 500
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 413 bits (1062), Expect = e-115
Identities = 227/447 (50%), Positives = 292/447 (65%), Gaps = 38/447 (8%)
Query: 139 HPPFAELLEPGSLGG--SDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPSEGGAGS 196
+PP L P G +PS L + A VK S TSP++P+E
Sbjct: 15 NPPLEALQSPSFRGNMADKLKDPSTLGF----------LEAAVKISHTSPDIPAE----- 59
Query: 197 GLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDPSSEERPPALPLP 256
+ + + + +Q T A +TR+ + R L +Q S D +E
Sbjct: 60 --VQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNE--------- 108
Query: 257 LPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRISFALRYLYGSDQL 316
LP E+ IG+IKPELY+ ++S G + T + CG+I+F+LRY Y ++ L
Sbjct: 109 LPPAAEQPTSIGRIKPELYK------QKSVDGEDAKSEATKS-CGKINFSLRYDYETETL 161
Query: 317 VVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAE 376
+VRIL+A DLPAKD G SDPYVKIYLLPDRK K QT+VHRKTLNP F+E F F VP E
Sbjct: 162 IVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEE 221
Query: 377 LAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELN 436
LA RKLH SV+DFDRFSRHD+IG+V+LDNL E ++ + +W+DI SE DLGE+
Sbjct: 222 LADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIM 281
Query: 437 FSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNP 496
FSLCYLPTAGRLT+T+IK NLKAMD+TG+SDPYVK SL+ +GRRLKK+KT+IKKNTLNP
Sbjct: 282 FSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNP 341
Query: 497 TYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLAN 556
YNEA++FD+ PE+++ V L I+V+DYD +GHNE+IGVCRVG A+ GR+HW EMLA
Sbjct: 342 VYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVG-ITAEGLGRDHWNEMLAY 400
Query: 557 PRKPVEHWHQLVEEKTVTSFTKGSKGL 583
PRKP+ HWH LVE K SF +G+ L
Sbjct: 401 PRKPIAHWHSLVEVK--KSFKEGNPRL 425
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 283 bits (723), Expect = 4e-76
Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 7/297 (2%)
Query: 288 GPGSGEAGTGAP-CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD 346
G G GE G++ F+L Y + ++QL V +LQA +LPA D G SDPYVK++LLPD
Sbjct: 127 GEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD 186
Query: 347 RKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDN 405
+KKK++TKVHRKTLNP FNETF F VP EL + L ++YDFDRFS+HD+IG+V V N
Sbjct: 187 KKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246
Query: 406 LLELAEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464
++L QP + WRD+ G E+ + LG++ SL Y+PTAG+LTV I++A NLK MD+
Sbjct: 247 TVDLG-QPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVG 303
Query: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524
G SDPYVK L+ G+RLKK+KT++KK TLNP +NE+ F++ E ++ V + + V+DYD
Sbjct: 304 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
Query: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSK 581
+G NE IG VG +A R HW++MLANPR+P+ WH L E+ V + +K
Sbjct: 364 KLGKNEAIGKIFVGSNATGTELR-HWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 283 bits (723), Expect = 4e-76
Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 7/297 (2%)
Query: 288 GPGSGEAGTGAP-CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD 346
G G GE G++ F+L Y + ++QL V +LQA +LPA D G SDPYVK++LLPD
Sbjct: 127 GEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD 186
Query: 347 RKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDN 405
+KKK++TKVHRKTLNP FNETF F VP EL + L ++YDFDRFS+HD+IG+V V N
Sbjct: 187 KKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246
Query: 406 LLELAEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464
++L QP + WRD+ G E+ + LG++ SL Y+PTAG+LTV I++A NLK MD+
Sbjct: 247 TVDLG-QPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVG 303
Query: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524
G SDPYVK L+ G+RLKK+KT++KK TLNP +NE+ F++ E ++ V + + V+DYD
Sbjct: 304 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
Query: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSK 581
+G NE IG VG +A R HW++MLANPR+P+ WH L E+ V + +K
Sbjct: 364 KLGKNEAIGKIFVGSNATGTELR-HWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 281 bits (720), Expect = 9e-76
Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)
Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
G++ ++L Y + ++QL+V I+QA +LPA D G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419
NPVFNE F F VP +EL + L +VYDFDRFS+HD+IG+ V N ++ + W
Sbjct: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260
Query: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478
RD+ E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK L+
Sbjct: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320
Query: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
G+RLKK+KT+IKKNTLNP YNE+ F+V E ++ V + + V+DYD IG N+ IG VG
Sbjct: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380
Query: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573
++ R HW++MLANPR+P+ WH L E+ V
Sbjct: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414
Score = 79.7 bits (195), Expect = 7e-15
Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)
Query: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381
PA G D + K+ K+KF ++H+ L P L L +K
Sbjct: 29 PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82
Query: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431
F + + + + ++ +L + D+ L D E G E+
Sbjct: 83 CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142
Query: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491
LG+L +SL Y +L V II+A+ L A+D+ G SDPYVK L+ + + KK +T + +
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
Query: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550
TLNP +NE F V + L +AV D+D +++IG +V + D H E W
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
Query: 551 AEMLANPRKPVE 562
++ + ++ E
Sbjct: 261 RDLQSAEKEEQE 272
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 281 bits (720), Expect = 9e-76
Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)
Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
G++ ++L Y + ++QL+V I+QA +LPA D G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419
NPVFNE F F VP +EL + L +VYDFDRFS+HD+IG+ V N ++ + W
Sbjct: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260
Query: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478
RD+ E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK L+
Sbjct: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320
Query: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
G+RLKK+KT+IKKNTLNP YNE+ F+V E ++ V + + V+DYD IG N+ IG VG
Sbjct: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380
Query: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573
++ R HW++MLANPR+P+ WH L E+ V
Sbjct: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414
Score = 79.7 bits (195), Expect = 7e-15
Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)
Query: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381
PA G D + K+ K+KF ++H+ L P L L +K
Sbjct: 29 PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82
Query: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431
F + + + + ++ +L + D+ L D E G E+
Sbjct: 83 CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142
Query: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491
LG+L +SL Y +L V II+A+ L A+D+ G SDPYVK L+ + + KK +T + +
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
Query: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550
TLNP +NE F V + L +AV D+D +++IG +V + D H E W
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
Query: 551 AEMLANPRKPVE 562
++ + ++ E
Sbjct: 261 RDLQSAEKEEQE 272
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 281 bits (720), Expect = 9e-76
Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)
Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
G++ ++L Y + ++QL+V I+QA +LPA D G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
Query: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419
NPVFNE F F VP +EL + L +VYDFDRFS+HD+IG+ V N ++ + W
Sbjct: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260
Query: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478
RD+ E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK L+
Sbjct: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320
Query: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
G+RLKK+KT+IKKNTLNP YNE+ F+V E ++ V + + V+DYD IG N+ IG VG
Sbjct: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380
Query: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573
++ R HW++MLANPR+P+ WH L E+ V
Sbjct: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414
Score = 79.7 bits (195), Expect = 7e-15
Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)
Query: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381
PA G D + K+ K+KF ++H+ L P L L +K
Sbjct: 29 PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82
Query: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431
F + + + + ++ +L + D+ L D E G E+
Sbjct: 83 CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142
Query: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491
LG+L +SL Y +L V II+A+ L A+D+ G SDPYVK L+ + + KK +T + +
Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
Query: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550
TLNP +NE F V + L +AV D+D +++IG +V + D H E W
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
Query: 551 AEMLANPRKPVE 562
++ + ++ E
Sbjct: 261 RDLQSAEKEEQE 272
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 271 bits (692), Expect = 2e-72
Identities = 141/283 (49%), Positives = 193/283 (68%), Gaps = 9/283 (3%)
Query: 288 GPGSGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDR 347
GPG + GR+ ++L Y + S QL+V ILQA+ L A D G SDPYV++YLLPD+
Sbjct: 98 GPGQ-QVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDK 156
Query: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407
+++++TKVHR+TLNP F ETF F VP EL R L +VYDFDRFSR+D IG+V +
Sbjct: 157 RRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEV----RV 212
Query: 408 ELAEQPPDRPL--WRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464
++ RP+ WR++ E+ + LG++ FSL Y+PTAG+LTV +++A NLK MD+
Sbjct: 213 PMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVG 272
Query: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524
G SDPYVK L+ G++++K+KT+IKKNTLNP YNEA F+V + V+ V + + V+DYD
Sbjct: 273 GLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYD 332
Query: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567
+G NE IG VG AA G HWA+MLANPR+P+ WH L
Sbjct: 333 KLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPIAQWHSL 374
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 231 bits (589), Expect = 1e-60
Identities = 127/286 (44%), Positives = 175/286 (61%), Gaps = 11/286 (3%)
Query: 289 PGSGEAGTGAPC-----GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYL 343
PGS E C GRI F++ Y + L V+I++A +LPAKD +G SDP+VKIYL
Sbjct: 120 PGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYL 179
Query: 344 LPDRKKKFQTKVHRKTLNPVFNETFQFS-VPLAELAQRKLHFSVYDFDRFSRHDLIGQVV 402
LPD+K K +TKV RK LNP +NETF F P ++ QR L+ V D+DRFSR+D IG+V
Sbjct: 180 LPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVS 239
Query: 403 LD-NLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAM 461
+ N ++L + + W+D+ GEL SLCY P+A + V IIKA NLKAM
Sbjct: 240 IPLNKVDLTQM---QTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAM 296
Query: 462 DLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVV 521
D+ G SDPYVK L+ + +R++K+KT K LNP +NE+ FD+ E + + I V+
Sbjct: 297 DIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVM 356
Query: 522 DYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567
D D + N+VIG + + P +HW +M+A PR+PV WHQL
Sbjct: 357 DKDKLSRNDVIGKIYLSWKSG-PGEVKHWKDMIARPRQPVAQWHQL 401
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 211 bits (538), Expect = 1e-54
Identities = 128/333 (38%), Positives = 186/333 (55%), Gaps = 22/333 (6%)
Query: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
PSS LP+ + GEE I + P G P S E G +
Sbjct: 113 PSSGSCIDQLPIKMDYGEELRSPITSLTP---------GESKTTSPSSPEEDV--MLGSL 161
Query: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPDRKKKFQTKVHRKTLNP 362
+F++ Y + LVV I +A LP D SDPY+K+ +LPD++ + +T+V RKTL+P
Sbjct: 162 TFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDP 221
Query: 363 VFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDR---PL 418
VF+ETF F +P ++L LHF V FDRFSR D+IG+V ++ LA P L
Sbjct: 222 VFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEV----MVPLAGVDPSTGKVQL 277
Query: 419 WRDIVEGGSEKA-DLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFS-DPYVKASLI 476
RDI++ +K GEL SL Y P A R+TV ++KA +L MD+TG S +PYVK ++
Sbjct: 278 TRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVY 337
Query: 477 SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCR 536
+R+ K+KT +KK TLNP +NE+ ++D+ + + ++ + V+D+D NEV+G
Sbjct: 338 YGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLI 397
Query: 537 VGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
+G + G EHW E+ +PRKPV WH L E
Sbjct: 398 LGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 198 bits (503), Expect = 1e-50
Identities = 111/273 (40%), Positives = 166/273 (60%), Gaps = 7/273 (2%)
Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPDRKKKFQTKVHRKT 359
G + F+L Y + VV I +A LPA D SDPY+K+ +LP++K K +T+V RKT
Sbjct: 155 GTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKT 214
Query: 360 LNPVFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRP 417
L+P F+ETF F +P ++ + LHF++ FDRFSR D+IG+V++ + +EL+E
Sbjct: 215 LDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGK--ML 272
Query: 418 LWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLI 476
+ R+I++ K+ GEL SLCY T LTV ++KA +L D++G SDPYVK +L
Sbjct: 273 MNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLY 332
Query: 477 SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCR 536
+R+ K+KT +KK T N +NE VFD+ E +E++ + V+D + NEVIG
Sbjct: 333 HAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLV 392
Query: 537 VGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
+G AA+ G EHW E+ PR+ + WH L +
Sbjct: 393 LGA-AAEGTGGEHWKEICDYPRRQIAKWHVLCD 424
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 4/104 (3%)
Query: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGF-SDPYVKASLISEGRRLKKRKTSIK 490
LG L FSL Y V I +A L AMD SDPY+K +++ E + K KT +
Sbjct: 154 LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKH--KVKTRVL 211
Query: 491 KNTLNPTYNEALVFDVAP-ESVENVGLSIAVVDYDCIGHNEVIG 533
+ TL+P ++E F P ++ + L ++ +D +++IG
Sbjct: 212 RKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIG 255
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 184 bits (468), Expect = 2e-46
Identities = 105/274 (38%), Positives = 152/274 (55%), Gaps = 9/274 (3%)
Query: 301 GRISFALRYLYGSDQLVVRILQALDLP-------AKDSNGFSDPYVKIYLLPDRKKKFQT 353
G + F+ +Y + L VR+++A DLP ++ S+PYVKI LLPD+K QT
Sbjct: 186 GMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQT 245
Query: 354 KVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQP 413
V RKT PVF E + F +P E +R L +V DFD+FSRH +IG+V + L E+ +
Sbjct: 246 GVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP-LCEV-DLV 303
Query: 414 PDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA 473
W+ ++ + +LGEL SL YLP+AGRL V +I+A L D++ SDP+VK
Sbjct: 304 KGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKI 363
Query: 474 SLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIG 533
L+ + +K +KTS + T++P YNE+ F V E +EN L V ++ N+ IG
Sbjct: 364 QLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIG 423
Query: 534 VCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567
+G ++ P HW ML R VE WH L
Sbjct: 424 RIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
Score = 49.7 bits (117), Expect = 8e-06
Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 9/133 (6%)
Query: 429 KADLGELNFSLCYLPTAGRLTVTIIKASNLK-------AMDLTGFSDPYVKASLISEGRR 481
K LG L+FS Y LTV +I+A +L + S+PYVK L+ + +
Sbjct: 182 KYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKN 241
Query: 482 LKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
K +T +K+ T P + E F++ + L + VVD+D + VIG V
Sbjct: 242 SK--QTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCE 299
Query: 542 ADPHGREHWAEML 554
D HW + L
Sbjct: 300 VDLVKGGHWWKAL 312
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 165 bits (418), Expect = 9e-41
Identities = 152/510 (29%), Positives = 212/510 (41%), Gaps = 74/510 (14%)
Query: 130 PHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELP 189
P H A A + PG G D P + + P A+ A S+ S
Sbjct: 194 PKHPARAPARGDSEDRRGPGQKTGPD-PASAPGRGNYGPPVRRASEARMSSSSRDSESWD 252
Query: 190 SEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLT-SQPDPSS-- 246
GGAG S GL A S Q + + PA P+P T S+P P
Sbjct: 253 HSGGAGDS----SRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAG 308
Query: 247 ---EERPPALP----LPLPGGEEKA------KLIGQIKPELYQGTGPGGRRSGGGPGSGE 293
+++P P P EE+ +G + + +GP + S P
Sbjct: 309 RFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAA 368
Query: 294 AGTGAP------------------CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFS 335
A P G + F+L Y + L I++A L DSNG +
Sbjct: 369 ARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLA 428
Query: 336 DPYVKIYLLPDRKK--KFQTKVHRKTLNPVFNETFQFSVPLAELAQRK-LHFSVYDFDRF 392
DPYVK++LLP K K +TK R T NP++NET + E QRK L SV D D+F
Sbjct: 429 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 488
Query: 393 SRHDLIGQVVLDNLLELAEQPPDR------------PLWR---------------DIVEG 425
++ IG+ L + P++ P+ R + VE
Sbjct: 489 GHNEFIGET----RFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER 544
Query: 426 GSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKR 485
+ + G++ SL Y G L V II+ +L AMD G+SDP+VK L + + K
Sbjct: 545 VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKH 604
Query: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPH 545
KT IKK TLNP +NE +D+ + L I+V DYD N+ IG C++G A
Sbjct: 605 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 664
Query: 546 GREHWAEMLANPRKPVEHWHQLVEEKTVTS 575
+HW E L N K +E WHQL E V+S
Sbjct: 665 -LKHWYECLKNKDKKIERWHQLQNENHVSS 693
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 165 bits (418), Expect = 9e-41
Identities = 152/510 (29%), Positives = 212/510 (41%), Gaps = 74/510 (14%)
Query: 130 PHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELP 189
P H A A + PG G D P + + P A+ A S+ S
Sbjct: 190 PKHPARAPARGDSEDRRGPGQKTGPD-PASAPGRGNYGPPVRRASEARMSSSSRDSESWD 248
Query: 190 SEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLT-SQPDPSS-- 246
GGAG S GL A S Q + + PA P+P T S+P P
Sbjct: 249 HSGGAGDS----SRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAG 304
Query: 247 ---EERPPALP----LPLPGGEEKA------KLIGQIKPELYQGTGPGGRRSGGGPGSGE 293
+++P P P EE+ +G + + +GP + S P
Sbjct: 305 RFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAA 364
Query: 294 AGTGAP------------------CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFS 335
A P G + F+L Y + L I++A L DSNG +
Sbjct: 365 ARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLA 424
Query: 336 DPYVKIYLLPDRKK--KFQTKVHRKTLNPVFNETFQFSVPLAELAQRK-LHFSVYDFDRF 392
DPYVK++LLP K K +TK R T NP++NET + E QRK L SV D D+F
Sbjct: 425 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 484
Query: 393 SRHDLIGQVVLDNLLELAEQPPDR------------PLWR---------------DIVEG 425
++ IG+ L + P++ P+ R + VE
Sbjct: 485 GHNEFIGET----RFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER 540
Query: 426 GSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKR 485
+ + G++ SL Y G L V II+ +L AMD G+SDP+VK L + + K
Sbjct: 541 VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKH 600
Query: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPH 545
KT IKK TLNP +NE +D+ + L I+V DYD N+ IG C++G A
Sbjct: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660
Query: 546 GREHWAEMLANPRKPVEHWHQLVEEKTVTS 575
+HW E L N K +E WHQL E V+S
Sbjct: 661 -LKHWYECLKNKDKKIERWHQLQNENHVSS 689
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 165 bits (417), Expect = 1e-40
Identities = 113/329 (34%), Positives = 165/329 (50%), Gaps = 19/329 (5%)
Query: 242 PDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCG 301
P P+SE LP GG A ++G I PELY+ P + P G
Sbjct: 103 PCPASE----LLPHTSSGGLGDACMVGAINPELYKF--PEDKSETDFPDGC-------LG 149
Query: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
R+ F++ Y +++L+V +++A L A P VK+YLLPD ++ Q+K RKT N
Sbjct: 150 RLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKTKRKTSN 207
Query: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
P F+E F F V + QR L FSVY DR +H L+GQV+ E R +WRD
Sbjct: 208 PQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRD 267
Query: 422 I-VEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
+ E ++ G+L F L Y RLTV +++A L+ + G +VK SL++ +
Sbjct: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNK 327
Query: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
+K +KTS ++NP YNE F ++ LS+ VV ++ +G VGP
Sbjct: 328 FVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGP- 386
Query: 541 AADPHGR--EHWAEMLANPRKPVEHWHQL 567
GR EHW EML+ P++ V+ WH L
Sbjct: 387 YMYTRGRELEHWDEMLSKPKELVKRWHAL 415
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 156 bits (395), Expect = 4e-38
Identities = 102/282 (36%), Positives = 150/282 (53%), Gaps = 27/282 (9%)
Query: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTK 354
G GR+ +L + +GS ++ V + QA DL G DPY ++ + + +TK
Sbjct: 113 GDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHETK 169
Query: 355 VHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQ-------VVLDNLL 407
VHR TL PVF+ET F +P AEL L +++F RFS H+ +G+ V L ++L
Sbjct: 170 VHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVL 229
Query: 408 E--LAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTG 465
E PP ++ +GEL FSL Y+P++GRLTV +++A L+ G
Sbjct: 230 EHWYLLGPP----------AATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PG 275
Query: 466 FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDC 525
++PYVK L+ R+ KKRKT+ KK T P +NEA F V V+NV L +AV D
Sbjct: 276 LAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSL 335
Query: 526 IGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567
E +G +G A+ +HWA+MLA+ R+P+ H L
Sbjct: 336 PLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 150 bits (378), Expect = 4e-36
Identities = 89/277 (32%), Positives = 151/277 (54%), Gaps = 6/277 (2%)
Query: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK 350
S G G++ ++ Y S L V ++Q DL ++ F ++++ LLPD +
Sbjct: 144 SNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIV 203
Query: 351 FQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLEL 409
+++ R + F+E F + L ++ L FSV+ D R+ G V L ++L+L
Sbjct: 204 GISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDL 263
Query: 410 AEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSD 468
QP L+ ++ ++ AD +GE+ SL YLPTA RLTV ++KA NL + +D
Sbjct: 264 PLQPFSGWLY---LQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTAD 320
Query: 469 PYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGH 528
P+VK L+ +GR++ K+KT++K++ NP +NEA++F V ++++ L + V + G
Sbjct: 321 PFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGR 380
Query: 529 NEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWH 565
+ +G +GP A+ G HW +MLA R+PV WH
Sbjct: 381 GDNVGHVIIGPSASG-MGTTHWNQMLATLRRPVSMWH 416
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 147 bits (372), Expect = 2e-35
Identities = 106/342 (30%), Positives = 154/342 (45%), Gaps = 31/342 (9%)
Query: 259 GGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRISFALRYLYGSDQLVV 318
GGE A L+ G G S ++ G + F L Y S L
Sbjct: 49 GGEAPAHLVPLALAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHC 108
Query: 319 RILQALDLPAKDSNGFSDPYVKIYLLPDRKK--KFQTKVHRKTLNPVFNETFQFS-VPLA 375
IL+A L D NG +DPYVK++LLP K K +TK R TLNPV+NE +S +
Sbjct: 109 SILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDD 168
Query: 376 ELAQRKLHFSVYDFDRFSRHDLIGQV-----------------VLDNLLELAEQPPDRPL 418
++ + L +V D D+ S ++ IG++ L+ + LA
Sbjct: 169 DITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAA 228
Query: 419 WRDIV----------EGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSD 468
R I +G + G + SL Y L V I++ ++L AMD+ G+SD
Sbjct: 229 LRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSD 288
Query: 469 PYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGH 528
PYVK L + + K KT +KK TLNP +NE +++ ++ L + V DYD
Sbjct: 289 PYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKS 348
Query: 529 NEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEE 570
N+ IG +GP A R+HW++ L P +E WH L E
Sbjct: 349 NDFIGGVSLGPGARG-EARKHWSDCLQQPDAALERWHTLTSE 389
>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
Length = 390
Score = 144 bits (363), Expect = 2e-34
Identities = 96/281 (34%), Positives = 141/281 (50%), Gaps = 16/281 (5%)
Query: 242 PDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCG 301
P P+SE LP GG A ++G I PELY+ P + P G
Sbjct: 103 PCPASE----LLPHTSSGGLGDACMVGAINPELYKF--PEDKSETDFPDGC-------LG 149
Query: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
R+ F++ Y +++L+V +++A L A P VK+YLLPD ++ Q+K RKT N
Sbjct: 150 RLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKTKRKTSN 207
Query: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
P F+E F F V + QR L FSVY DR +H L+GQV+ E R +WRD
Sbjct: 208 PQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRD 267
Query: 422 I-VEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
+ E ++ G+L F L Y RLTV +++A L+ + G +VK SL++ +
Sbjct: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNK 327
Query: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVV 521
+K +KTS ++NP YNE F ++ LS+ VV
Sbjct: 328 FVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 143 bits (361), Expect = 4e-34
Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 9/278 (3%)
Query: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKK--KFQTKVHRK 358
G + F+L Y ++ L I +A L D NG +DPYVK++LLP K K +TK R
Sbjct: 128 GTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRN 187
Query: 359 TLNPVFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQ--VVLDNLLELAEQPPD 415
TLNP +NET + + ++ ++ L SV D D+F ++ IG+ V L L + +
Sbjct: 188 TLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFN 247
Query: 416 RPLWRDIVEGGSEKADL---GELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVK 472
L + + +E L G + SL Y L V I++ ++L AMD G+SDPYVK
Sbjct: 248 ICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVK 307
Query: 473 ASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVI 532
L + + K KT++KK TLNP +NE +++ + L + V DYD N+ I
Sbjct: 308 TYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFI 367
Query: 533 GVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEE 570
G +G A +HW + L N K +E WH L E
Sbjct: 368 GGVVLGIHAKGER-LKHWFDCLKNKDKRIERWHTLTSE 404
Score = 82.8 bits (203), Expect = 8e-16
Identities = 53/130 (40%), Positives = 67/130 (51%), Gaps = 4/130 (3%)
Query: 412 QPPDRPLWRDIVEGGSEKAD---LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSD 468
+PP +P + G E D LG L+FSL Y L TI KA LK MD G +D
Sbjct: 104 RPPAKPPEDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLAD 163
Query: 469 PYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALV-FDVAPESVENVGLSIAVVDYDCIG 527
PYVK L+ + K +T +NTLNPT+NE L + + E + L I+V D D
Sbjct: 164 PYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFR 223
Query: 528 HNEVIGVCRV 537
HNE IG RV
Sbjct: 224 HNEFIGETRV 233
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 130 bits (326), Expect = 4e-30
Identities = 94/284 (33%), Positives = 142/284 (50%), Gaps = 48/284 (16%)
Query: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK 349
+G+ G GRI+F+L+Y + LVV + + L A ++ S+PYVK YLLPD+ +
Sbjct: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407
Query: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV------ 401
K +T + R T+NP+++ET ++ +P + LAQR L FSV+ RF R+ +G+
Sbjct: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
Query: 402 -----VLDNLLEL-----AEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTA------ 445
LD+ L L AE P P + GEL SL Y+P +
Sbjct: 468 WKLDKKLDHCLPLHGKISAESPTGLP------------SHKGELVVSLKYIPASKTPVGG 515
Query: 446 ----------GRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLN 495
G L V I +A NL A G SD +VK L+ + KRKT + K TLN
Sbjct: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575
Query: 496 PTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
P YN V++ V E ++++ L + V D + + N+ +G R+G
Sbjct: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619
Score = 55.8 bits (133), Expect = 1e-07
Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 433 GELNFSLCYLPTAGRLTVTIIKASNLKAMD-LTGFSDPYVKASLISEGRRLKKRKTSIKK 491
G + FSL Y L V + + L D S+PYVK L+ + R KRKTSIK+
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
+T+NP Y+E L +++ + L +V + G N +G + D+
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 130 bits (326), Expect = 4e-30
Identities = 94/284 (33%), Positives = 142/284 (50%), Gaps = 48/284 (16%)
Query: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK 349
+G+ G GRI+F+L+Y + LVV + + L A ++ S+PYVK YLLPD+ +
Sbjct: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407
Query: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV------ 401
K +T + R T+NP+++ET ++ +P + LAQR L FSV+ RF R+ +G+
Sbjct: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
Query: 402 -----VLDNLLEL-----AEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTA------ 445
LD+ L L AE P P + GEL SL Y+P +
Sbjct: 468 WKLDKKLDHCLPLHGKISAESPTGLP------------SHKGELVVSLKYIPASKTPVGG 515
Query: 446 ----------GRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLN 495
G L V I +A NL A G SD +VK L+ + KRKT + K TLN
Sbjct: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575
Query: 496 PTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
P YN V++ V E ++++ L + V D + + N+ +G R+G
Sbjct: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619
Score = 55.8 bits (133), Expect = 1e-07
Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 433 GELNFSLCYLPTAGRLTVTIIKASNLKAMD-LTGFSDPYVKASLISEGRRLKKRKTSIKK 491
G + FSL Y L V + + L D S+PYVK L+ + R KRKTSIK+
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
+T+NP Y+E L +++ + L +V + G N +G + D+
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
Length = 550
Score = 119 bits (297), Expect = 1e-26
Identities = 118/459 (25%), Positives = 188/459 (40%), Gaps = 38/459 (8%)
Query: 131 HHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPS 190
HH+AH A + S G P D EAA G +P T E P
Sbjct: 92 HHNAHFGSDLVRASMRRKKSTRGDQAP-----GHDREAEAAVKEKEEGPEPRLTIDEAPQ 146
Query: 191 E-------GGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPD 243
E G G + + L P + PRP QT +
Sbjct: 147 ERLRETEASDPEEASQAQEDPGQGDQQVCAEEADPELEPASGGEQEPRPQQAQTKAASQI 206
Query: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
+ E P P P + + L T G + S SG+A G +
Sbjct: 207 LENGEEAPG---PDPSLDRMLSSSSSVS-SLNSSTLSGSQMSL----SGDAEAVQVRGSV 258
Query: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPV 363
FAL Y G+ +L V ++Q L A SDPYVK YLLPD++ K +T V ++ LNPV
Sbjct: 259 HFALHYEPGAAELRVHVIQCQGLAAARRRR-SDPYVKSYLLPDKQSKRKTAVKKRNLNPV 317
Query: 364 FNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRPLWRDI 422
FNET ++SVP AEL R L SV+ + R+ +G+V + + + +P PL +
Sbjct: 318 FNETLRYSVPQAELQGRVLSLSVWHRESLGRNIFLGEVEVPLDTWDWGSEPTWLPLQPRV 377
Query: 423 VEGGSEKADLGELNFSLCY---------LPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA 473
+ G L SL Y LP +G L + +A +L + G D YV+
Sbjct: 378 PPSPDDLPSRGLLALSLKYVPAGSEGAGLPPSGELHFWVKEARDLLPL-RAGSLDTYVQC 436
Query: 474 SLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVI 532
++ + + +++T + + +L+P +N +V+D P + +++ D+ + N +
Sbjct: 437 FVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGALA-NRQL 495
Query: 533 GVCRVGPDAADPHGRE-HWAEMLANPRKPVEHWHQLVEE 570
G R+ +G + W + + + W L+E+
Sbjct: 496 GGTRLSLGTGSSYGLQVPWMDSTPEEK---QLWQALLEQ 531
>gi|24308233 synaptotagmin XIII [Homo sapiens]
Length = 426
Score = 115 bits (287), Expect = 1e-25
Identities = 101/351 (28%), Positives = 164/351 (46%), Gaps = 24/351 (6%)
Query: 230 PRP-LTQQTLTSQPDPS--SEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRS- 285
PRP +T + + D S S E P A P P + + K Q+ EL+ G
Sbjct: 85 PRPAVTAPEVINYADYSLRSTEEPTAPASPQPPNDSRLKR--QVTEELFILPQNGVVEDV 142
Query: 286 ----GGGPGSGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKI 341
P + AP ++ + L Y +L V L+A+ + +G D YV+
Sbjct: 143 CVMETWNPEKAASWNQAP--KLHYCLDYDCQKAELFVTRLEAV---TSNHDGGCDCYVQG 197
Query: 342 YLLPDRKK-KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQ 400
+ + QT + ++ L+ + E + EL L ++ DRFSRH + G+
Sbjct: 198 SVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGE 257
Query: 401 VVLDNLLELAEQPPDRPLWRDIVEGGSE-KADLGELNFSLCYLPTAGRLTVTIIKASNL- 458
+ L L+ P W ++ E A GE+ S+ YLP A RL V +IKA NL
Sbjct: 258 LRLG--LDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLH 315
Query: 459 --KAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGL 516
++ +L G D VK +L + R+LKK++T K+ +NP +NE ++F++ + ++ +
Sbjct: 316 SNQSKELLG-KDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSV 374
Query: 517 SIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567
+ V+ D G + +G C +G + R HW EML NPR+ + WHQL
Sbjct: 375 ELEVLGQDDSGQSCALGHCSLGLHTSGSE-RSHWEEMLKNPRRQIAMWHQL 424
>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
Length = 910
Score = 112 bits (280), Expect = 1e-24
Identities = 101/358 (28%), Positives = 166/358 (46%), Gaps = 35/358 (9%)
Query: 231 RPLTQQTLTSQPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPG 290
+P+T + + P S+ P P P +K K + + P Q G S
Sbjct: 545 KPVTNECV---PRISTVPTQPDNPFSHP---DKLKRMSKSVPAFLQDEVSGSVMS---VY 595
Query: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349
SG+ G G I FA+ Y+ +L V + Q DL A D SDPYVK YLLPD+ K
Sbjct: 596 SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 655
Query: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407
K +T V +KTLNPV+NE ++ + L +KL+ S++ D F R+ +G+V LD L
Sbjct: 656 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 713
Query: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451
E + + PL R E + GE+ +L Y LPT G + +
Sbjct: 714 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 773
Query: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510
+ + +L + + + +VK +++ + R ++KT T NP +N +V+D PE
Sbjct: 774 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 832
Query: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568
+ + + V D+ + N+ +G R+G +G E + + + + V W ++V
Sbjct: 833 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 887
>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
Length = 376
Score = 112 bits (279), Expect = 1e-24
Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)
Query: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349
SG+ G G I FA+ Y+ +L V + Q DL A D SDPYVK YLLPD+ K
Sbjct: 62 SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 121
Query: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407
K +T V +KTLNPV+NE ++ + L +KL+ S++ D F R+ +G+V LD L
Sbjct: 122 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 179
Query: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451
E + + PL R E + GE+ +L Y LPT G + +
Sbjct: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 239
Query: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510
+ + +L + + + +VK +++ + R ++KT T NP +N +V+D PE
Sbjct: 240 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 298
Query: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568
+ + + V D+ + N+ +G R+G +G E + + + + V W ++V
Sbjct: 299 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 353
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.137 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,014,915
Number of Sequences: 37866
Number of extensions: 1685335
Number of successful extensions: 12520
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 582
Number of HSP's that attempted gapping in prelim test: 9666
Number of HSP's gapped (non-prelim): 2686
length of query: 590
length of database: 18,247,518
effective HSP length: 108
effective length of query: 482
effective length of database: 14,157,990
effective search space: 6824151180
effective search space used: 6824151180
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.