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Search of human proteins with 238231453
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
(419 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 849 0.0
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 535 e-152
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 378 e-105
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 183 2e-46
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 182 5e-46
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 179 3e-45
gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens] 173 3e-43
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 173 3e-43
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 173 3e-43
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 168 1e-41
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 161 9e-40
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 156 3e-38
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 122 5e-28
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 122 5e-28
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 99 5e-21
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 99 5e-21
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 99 5e-21
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 99 5e-21
gi|37674210 slingshot 2 [Homo sapiens] 97 4e-20
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 94 3e-19
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 89 6e-18
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 80 3e-15
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 80 4e-15
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 80 4e-15
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 80 4e-15
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 80 4e-15
gi|239582767 slingshot homolog 3 [Homo sapiens] 79 6e-15
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 74 3e-13
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 71 2e-12
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 70 5e-12
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 849 bits (2193), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MKNQLRGPPARAHMSTSGAAAAGGTRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWL 60
MKNQLRGPPARAHMSTSGAAAAGGTRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWL
Sbjct: 1 MKNQLRGPPARAHMSTSGAAAAGGTRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWL 60
Query: 61 QEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHAD 120
QEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHAD
Sbjct: 61 QEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHAD 120
Query: 121 KERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQT 180
KERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQT
Sbjct: 121 KERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQT 180
Query: 181 EYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSS 240
EYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSS
Sbjct: 181 EYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSS 240
Query: 241 QPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISD 300
QPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISD
Sbjct: 241 QPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISD 300
Query: 301 HWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDF 360
HWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDF
Sbjct: 301 HWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDF 360
Query: 361 VKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST 419
VKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
Sbjct: 361 VKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST 419
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 535 bits (1377), Expect = e-152
Identities = 264/367 (71%), Positives = 314/367 (85%), Gaps = 5/367 (1%)
Query: 55 KSAEWLQEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSI 114
K+ WL E+LE G LLL+DCRP EL+ESSHIE+AIN+AIPG+MLRRL+KGNLP+R++
Sbjct: 18 KTVAWLNEQLEL-GNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRAL 76
Query: 115 IPNHADKERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGG 174
D++RF RC TV+LYDE++++W G SVLGLLL+KL+D+GC+A+YL+GG
Sbjct: 77 FTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGE-SVLGLLLKKLKDEGCRAFYLEGG 135
Query: 175 FNKFQTEYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCS-DGESDREL-PSSATES 232
F+KFQ E+S HCETN+D S S SSSPP VLGLGGLRISSD S D ESD + P+SAT+S
Sbjct: 136 FSKFQAEFSLHCETNLDGSCS-SSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDS 194
Query: 233 DGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFT 292
DGSP+ +SQP+FPV+ILP+LYLGCAKDSTNLDVL ++GIKYILNVTPNLPN FE+ GEF
Sbjct: 195 DGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFK 254
Query: 293 YKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNL 352
YKQIPISDHWSQNLSQFFPEAISFIDEAR K CGVLVHCLAGISRSVTVTVAYLMQK+NL
Sbjct: 255 YKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNL 314
Query: 353 SLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFP 412
S+NDAYD VK KKSNISPNFNFMGQLLDFERTLGLSSPCDN ++QLYF+TP+N N++
Sbjct: 315 SMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQ 374
Query: 413 LNTLEST 419
+++L+ST
Sbjct: 375 VDSLQST 381
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 378 bits (970), Expect = e-105
Identities = 213/382 (55%), Positives = 262/382 (68%), Gaps = 29/382 (7%)
Query: 55 KSAEWLQEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSI 114
+S WL+ EL LLLLDCR EL+ES+ I A+++A+P L+LRRLR+G+L +R++
Sbjct: 6 RSCLWLRRELSPPR-PRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRAL 64
Query: 115 IPNHADKERFATRCKAATVLLYDEA-------TAEWQPEPGAPASVLGLLLQKLRDDGCQ 167
+P + A VLLYD+ AE + E SVLG LLQKLR++G
Sbjct: 65 LPGPPLQPP-----PPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYL 119
Query: 168 AYYLQGGFNKFQTEYSEHCETNVDSSSSPSSSP---PTSVLGLGGLRISSDCSDGES--D 222
AYYLQGGF++FQ E CET++ + S +P P V+GLG L + SDCSD ES D
Sbjct: 120 AYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEAD 179
Query: 223 RELPSSATESDGSPVP--SSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPN 280
R+ S +S+G+ P + +FPVQILP LYLG A+DS NL+ L K GI+YILNVTPN
Sbjct: 180 RDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPN 239
Query: 281 LPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVT 340
LPN FE G+F YKQIPISDHWSQNLS+FFPEAI FIDEA S+ CGVLVHCLAG+SRSVT
Sbjct: 240 LPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVT 299
Query: 341 VTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGL---------SSPC 391
VTVAYLMQK++LSLNDAYD VKRKKSNISPNFNFMGQLLDFER+L L S
Sbjct: 300 VTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQ 359
Query: 392 DNHASSEQLYFSTPTNHNLFPL 413
+ AS+ +F+TPT+ F L
Sbjct: 360 ASAASNPPSFFTTPTSDGAFEL 381
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 183 bits (465), Expect = 2e-46
Identities = 105/314 (33%), Positives = 167/314 (53%), Gaps = 25/314 (7%)
Query: 73 LLLDCRPHELFESSHIETAINL-AIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAA 131
+++DCRP + SHI+ A+++ + RRL++G + + +I K+ F R +
Sbjct: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFK-RIFSK 231
Query: 132 TVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVD 191
+++YDE T E P P+ L ++L+ L+ +G + L+GG + F+ + C+ ++
Sbjct: 232 EIIVYDENTNE--PSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQ 289
Query: 192 SSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQILPY 251
+C + SS P + A ILP+
Sbjct: 290 LQ---------------------ECREVGGGASAASSLLPQPIPTTPDIENAELTPILPF 328
Query: 252 LYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFP 311
L+LG +D+ +LD + + I Y++NVT +LP G F YK++P +D QNL Q+F
Sbjct: 329 LFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFE 388
Query: 312 EAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPN 371
EA FI+EA G+L+HC AG+SRS T+ +AYLM+ +++ DAY FVK K+ ISPN
Sbjct: 389 EAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPN 448
Query: 372 FNFMGQLLDFERTL 385
NFMGQLL+FE L
Sbjct: 449 LNFMGQLLEFEEDL 462
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 182 bits (462), Expect = 5e-46
Identities = 125/365 (34%), Positives = 187/365 (51%), Gaps = 47/365 (12%)
Query: 37 SGAGTGAGAATGAGAMPCKSAEWLQEELEARGGASLLLLDCRPHELFESSHIETAINLAI 96
+G G G + G +P G LLLDCRP + +I ++N+
Sbjct: 24 NGGGAGGSGSHGTLGLP--------------SGGKCLLLDCRPFLAHSAGYILGSVNVRC 69
Query: 97 PGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAATVLLYDEATAEWQPEPGAPASVLGL 156
++RR KG++ + I+P + + V++YDE + + E S + L
Sbjct: 70 -NTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSP--RAESLREDSTVSL 126
Query: 157 LLQKLRDDG--CQAYYLQGGFNKFQTEYSEHCETNVDSSSSPSSSPP--TSVLGLGGLRI 212
++Q LR + L+GG+ +F +EY E C ++ P PP T L LG
Sbjct: 127 VVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLG---- 182
Query: 213 SSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIK 272
CS S G+P+ PV+ILP+LYLG A + D+L GI
Sbjct: 183 ---CS--------------SCGTPLHDQ--GGPVEILPFLYLGSAYHAARRDMLDALGIT 223
Query: 273 YILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCL 332
+LNV+ + PN FE G + YK IP+ D+ ++S +F EAI +ID + + VLVHC
Sbjct: 224 ALLNVSSDCPNHFE--GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQ 281
Query: 333 AGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSPCD 392
AGISRS T+ +AYLM K + L +A++FVK+++S ISPNF+FMGQLL FE + L++ C
Sbjct: 282 AGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV-LATSCA 340
Query: 393 NHASS 397
A+S
Sbjct: 341 AEAAS 345
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 179 bits (455), Expect = 3e-45
Identities = 119/329 (36%), Positives = 174/329 (52%), Gaps = 28/329 (8%)
Query: 70 ASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCK 129
A LLLDCR F + HI ++N+ ++RR KG + + I+PN + R
Sbjct: 22 AQCLLLDCRSFFAFNAGHIAGSVNVRF-STIVRRRAKGAMGLEHIVPNAELRGRLLAGAY 80
Query: 130 AATVLLYDEATA-EWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCET 188
A VLL + + A + G A G L ++ R Q ++L+GG+ F E C
Sbjct: 81 HAVVLLDERSAALDGAKRDGTLALAAGALCREAR--AAQVFFLKGGYEAFSASCPELC-- 136
Query: 189 NVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQI 248
S S+P +GL L +S+ D S+ + P PV+I
Sbjct: 137 ------SKQSTP----MGLS-LPLSTSVPD--------SAESGCSSCSTPLYDQGGPVEI 177
Query: 249 LPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQ 308
LP+LYLG A ++ D+L GI ++NV+ N PN FE G + YK IP+ D+ ++S
Sbjct: 178 LPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFE--GHYQYKSIPVEDNHKADISS 235
Query: 309 FFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNI 368
+F EAI FID ++ V VHC AGISRS T+ +AYLM+ + L++A++FVK+++S I
Sbjct: 236 WFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSII 295
Query: 369 SPNFNFMGQLLDFERTLGLSSPCDNHASS 397
SPNF+FMGQLL FE + L+ C A S
Sbjct: 296 SPNFSFMGQLLQFESQV-LAPHCSAEAGS 323
>gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens]
Length = 235
Score = 173 bits (438), Expect = 3e-43
Identities = 81/102 (79%), Positives = 93/102 (91%)
Query: 318 DEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQ 377
DEAR K CGVLVHCLAGISRSVTVTVAYLMQK+NLS+NDAYD VK KKSNISPNFNFMGQ
Sbjct: 134 DEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQ 193
Query: 378 LLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST 419
LLDFERTLGLSSPCDN ++QLYF+TP+N N++ +++L+ST
Sbjct: 194 LLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST 235
Score = 145 bits (365), Expect = 9e-35
Identities = 71/139 (51%), Positives = 96/139 (69%), Gaps = 2/139 (1%)
Query: 55 KSAEWLQEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSI 114
K+ WL E+LE G LLL+DCRP EL+ESSHIE+AIN+AIPG+MLRRL+KGNLP+R++
Sbjct: 18 KTVAWLNEQLEL-GNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRAL 76
Query: 115 IPNHADKERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGG 174
D++RF RC TV+LYDE++++W G SVLGLLL+KL+D+GC+A+YL+
Sbjct: 77 FTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGG-ESVLGLLLKKLKDEGCRAFYLEDE 135
Query: 175 FNKFQTEYSEHCETNVDSS 193
HC + S
Sbjct: 136 ARGKNCGVLVHCLAGISRS 154
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 173 bits (438), Expect = 3e-43
Identities = 123/357 (34%), Positives = 182/357 (50%), Gaps = 45/357 (12%)
Query: 60 LQEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHA 119
L++ L A ++LDCRP+ F +S++ ++N+ + ++LRR R G + R ++P+ A
Sbjct: 11 LRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLPDEA 70
Query: 120 DKERFATRCKA--ATVLLYDEATAEWQP--EPGAPASVLGLLLQKLRDDGCQAYYLQGGF 175
+ R A V++ D+ + WQ E A VL LL L G + Y+L+GG+
Sbjct: 71 ARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACL-PAGPRVYFLKGGY 129
Query: 176 NKFQTEYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGS 235
F +EY E C V + +I ES+R L S G
Sbjct: 130 ETFYSEYPECC---------------VDVKPISQEKI-------ESERALISQC----GK 163
Query: 236 PVP--SSQPAF----PVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGG 289
PV S +PA+ PV+ILP+LYLG A ++ + L I +LNV+ A
Sbjct: 164 PVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEAC--AT 221
Query: 290 EFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQK 349
YK IP+ D + ++S F EAI FID R K VLVHC AGISRS T+ +AYLM+
Sbjct: 222 HLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKT 281
Query: 350 MNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSP------CDNHASSEQL 400
L +A+D++K+++S +SPNF FMGQLL +E + S+P C A+ L
Sbjct: 282 KQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSL 338
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 173 bits (438), Expect = 3e-43
Identities = 116/320 (36%), Positives = 163/320 (50%), Gaps = 33/320 (10%)
Query: 65 EARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRS-IIPNHADKER 123
+ R LLLDCRP F H+ A + L+ RR R + + ++P+ A + R
Sbjct: 20 DPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLACLLPDRALRTR 79
Query: 124 FATRCKAATVLLYDEATAEWQPEPGAPASVL-GLLLQKLRDDGCQAYYLQGGFNKFQTEY 182
A V+L + + + + P +PA VL LL + R Y+L+GGF+ FQ
Sbjct: 80 LVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGFQG-- 137
Query: 183 SEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQP 242
C ++ S + + PPT T S P
Sbjct: 138 ---CCPDLCSEAPAPALPPTG------------------------DKTSRSDSRAPVYDQ 170
Query: 243 AFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHW 302
PV+ILPYL+LG S++L L GI +LNV+ + PN FE G F YK IP+ D+
Sbjct: 171 GGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFE--GLFRYKSIPVEDNQ 228
Query: 303 SQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVK 362
+S +F EAI FID ++ VLVHC AGISRS T+ +AYLMQ + L++A+DFVK
Sbjct: 229 MVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVK 288
Query: 363 RKKSNISPNFNFMGQLLDFE 382
+++ ISPNF+FMGQLL FE
Sbjct: 289 QRRGVISPNFSFMGQLLQFE 308
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 168 bits (425), Expect = 1e-41
Identities = 114/330 (34%), Positives = 175/330 (53%), Gaps = 57/330 (17%)
Query: 67 RGG-ASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFA 125
RGG L++D R + S H+ +++N+ L+ RRL++G + I +I A + A
Sbjct: 21 RGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQVEA 80
Query: 126 TRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGC--QAYYLQGGFNKFQTEYS 183
T + V++YD++T + A S L +LL KL DGC L GGF F + +
Sbjct: 81 T--EPQDVVVYDQSTRD--ASVLAADSFLSILLSKL--DGCFDSVAILTGGFATFSSCFP 134
Query: 184 EHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPA 243
CE P ++L P+ SQP
Sbjct: 135 GLCE-----------GKPAALL------------------------------PMSLSQPC 153
Query: 244 FPV------QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIP 297
PV +ILP+LYLG KD N D++ + GI Y+LN + + P + E + ++P
Sbjct: 154 LPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKP-DFICESRFMRVP 212
Query: 298 ISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDA 357
I+D++ + L + ++I FID+A+ C V+VHCLAGISRS T+ +AY+M+ M +S +DA
Sbjct: 213 INDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDA 272
Query: 358 YDFVKRKKSNISPNFNFMGQLLDFERTLGL 387
Y FVK ++ +ISPNFNF+GQLL++ER+L L
Sbjct: 273 YRFVKDRRPSISPNFNFLGQLLEYERSLKL 302
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 161 bits (408), Expect = 9e-40
Identities = 105/327 (32%), Positives = 169/327 (51%), Gaps = 45/327 (13%)
Query: 68 GGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATR 127
G +LL+D RP + +SHI AIN+ LM RRL++ + I +I H+ K +
Sbjct: 22 GTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELI-QHSAKHKVDID 80
Query: 128 CKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCE 187
C + V++YD+++ + + L +LL KL + L GGF +F + CE
Sbjct: 81 C-SQKVVVYDQSSQDVASL--SSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCE 137
Query: 188 TNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQ 247
+ S P V +G P +
Sbjct: 138 GKSTLVPTCISQPCLPVANIG------------------------------------PTR 161
Query: 248 ILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLS 307
ILP LYLGC +D N +++ + GI Y+LN + P + E + ++P++D + + +
Sbjct: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKP-DFIPESHFLRVPVNDSFCEKIL 220
Query: 308 QFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSN 367
+ +++ FI++A++ VLVHCLAGISRS T+ +AY+M++M++SL++AY FVK K+
Sbjct: 221 PWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPT 280
Query: 368 ISPNFNFMGQLLDFERTL----GLSSP 390
ISPNFNF+GQLLD+E+ + G S P
Sbjct: 281 ISPNFNFLGQLLDYEKKIKNQTGASGP 307
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 156 bits (395), Expect = 3e-38
Identities = 100/251 (39%), Positives = 139/251 (55%), Gaps = 29/251 (11%)
Query: 149 APASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVDSSSSPSSSPP--TSVLG 206
AP+ LG+ Q C QGG+ +F +EY E C ++ P PP T L
Sbjct: 31 APSMALGVS-QLAGRSRCLCSESQGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLD 89
Query: 207 LGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVL 266
LG CS S G+P+ PV+ILP+LYLG A + D+L
Sbjct: 90 LG-------CS--------------SCGTPLHDQ--GGPVEILPFLYLGSAYHAARRDML 126
Query: 267 GKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCG 326
GI +LNV+ + PN FE G + YK IP+ D+ ++S +F EAI +ID + +
Sbjct: 127 DALGITALLNVSSDCPNHFE--GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGR 184
Query: 327 VLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLG 386
VLVHC AGISRS T+ +AYLM K + L +A++FVK+++S ISPNF+FMGQLL FE +
Sbjct: 185 VLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV- 243
Query: 387 LSSPCDNHASS 397
L++ C A+S
Sbjct: 244 LATSCAAEAAS 254
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 122 bits (307), Expect = 5e-28
Identities = 59/118 (50%), Positives = 79/118 (66%)
Query: 268 KYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGV 327
+ I Y++NVT +LP G F YK++P +D QNL Q+F EA FI+EA G+
Sbjct: 3 RLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGL 62
Query: 328 LVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTL 385
L+HC AG+SRS T+ +AYLM+ +++ DAY FVK K+ ISPN NFMGQLL+FE L
Sbjct: 63 LIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 122 bits (307), Expect = 5e-28
Identities = 59/118 (50%), Positives = 79/118 (66%)
Query: 268 KYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGV 327
+ I Y++NVT +LP G F YK++P +D QNL Q+F EA FI+EA G+
Sbjct: 3 RLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGL 62
Query: 328 LVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTL 385
L+HC AG+SRS T+ +AYLM+ +++ DAY FVK K+ ISPN NFMGQLL+FE L
Sbjct: 63 LIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 99.4 bits (246), Expect = 5e-21
Identities = 58/155 (37%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
Query: 245 PVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQ 304
P I +LYLG +++NL+ L G+ YILNVT + N F G F Y I + D +
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETT 366
Query: 305 NLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRK 364
+L + EA FI++A+ LVHC G+SRS + +AY M++ L AY++VK+K
Sbjct: 367 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 426
Query: 365 KSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQ 399
+S PN FM QL ++E L S N +Q
Sbjct: 427 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQ 461
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 99.4 bits (246), Expect = 5e-21
Identities = 58/155 (37%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
Query: 245 PVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQ 304
P I +LYLG +++NL+ L G+ YILNVT + N F G F Y I + D +
Sbjct: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETT 377
Query: 305 NLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRK 364
+L + EA FI++A+ LVHC G+SRS + +AY M++ L AY++VK+K
Sbjct: 378 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 437
Query: 365 KSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQ 399
+S PN FM QL ++E L S N +Q
Sbjct: 438 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQ 472
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 99.4 bits (246), Expect = 5e-21
Identities = 58/155 (37%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
Query: 245 PVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQ 304
P I +LYLG +++NL+ L G+ YILNVT + N F G F Y I + D +
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETT 366
Query: 305 NLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRK 364
+L + EA FI++A+ LVHC G+SRS + +AY M++ L AY++VK+K
Sbjct: 367 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 426
Query: 365 KSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQ 399
+S PN FM QL ++E L S N +Q
Sbjct: 427 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQ 461
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 99.4 bits (246), Expect = 5e-21
Identities = 57/145 (39%), Positives = 79/145 (54%), Gaps = 3/145 (2%)
Query: 248 ILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLS 307
I P+L LG + +LD L K + +ILNV + NAF +FTYK I I D N+
Sbjct: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFL--SDFTYKSISILDLPETNIL 126
Query: 308 QFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSN 367
+FPE FI+EA+ K VLVHC AG+SR+ + + +LM S A+ VK + +
Sbjct: 127 SYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPS 186
Query: 368 ISPNFNFMGQLLDFERTLGLSSPCD 392
I PN FM QL ++ S+ CD
Sbjct: 187 ICPNSGFMEQLRTYQEGKE-SNKCD 210
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 96.7 bits (239), Expect = 4e-20
Identities = 50/141 (35%), Positives = 83/141 (58%), Gaps = 2/141 (1%)
Query: 245 PVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQ 304
P QI +++LG +++NL+ L G++YILNVT + N F G F Y I + D +
Sbjct: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFP--GVFEYHNIRVYDEEAT 365
Query: 305 NLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRK 364
+L ++ + FI +A+ LVHC G+SRS + +AY M++ +L+ AYD+VK +
Sbjct: 366 DLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKER 425
Query: 365 KSNISPNFNFMGQLLDFERTL 385
++ PN +FM QL +++ L
Sbjct: 426 RTVTKPNPSFMRQLEEYQGIL 446
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 93.6 bits (231), Expect = 3e-19
Identities = 55/137 (40%), Positives = 79/137 (57%), Gaps = 3/137 (2%)
Query: 247 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNL 306
+ILP LY+G KD+ + + L K + +IL+V + E Y IP +D SQNL
Sbjct: 7 KILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEG---VKYLCIPAADSPSQNL 63
Query: 307 SQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKS 366
++ F E+I FI E R + LVHCLAG+SRSVT+ +AY+M + DA V+ +S
Sbjct: 64 TRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRS 123
Query: 367 NISPNFNFMGQLLDFER 383
+PN F QL +FE+
Sbjct: 124 CANPNVGFQRQLQEFEK 140
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 89.4 bits (220), Expect = 6e-18
Identities = 51/139 (36%), Positives = 77/139 (55%), Gaps = 2/139 (1%)
Query: 247 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNL 306
QI L+LG ++N +L GI I+N T +PN + +F Y ++P++D +
Sbjct: 29 QITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNF--NWPQFEYVKVPLADMPHAPI 86
Query: 307 SQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKS 366
+F I K LVHC AG+SRS T+ +AYLM+ N+ L +AY++VK ++
Sbjct: 87 GLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 146
Query: 367 NISPNFNFMGQLLDFERTL 385
I PN F QL+D+ER L
Sbjct: 147 VIRPNVGFWRQLIDYERQL 165
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 80.5 bits (197), Expect = 3e-15
Identities = 58/157 (36%), Positives = 79/157 (50%), Gaps = 13/157 (8%)
Query: 232 SDGSPVPS--SQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTP-------NLP 282
SDGS S SQP ++ P +Y+G A + ++ L K GI ++LN N
Sbjct: 17 SDGSGCYSLPSQPCN--EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTN 74
Query: 283 NAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCG-VLVHCLAGISRSVTV 341
F TY I +D NLS +F A FID+A ++K G VLVHC G SRS T+
Sbjct: 75 ANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTL 134
Query: 342 TVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQL 378
+AYLM + + + A V R+ I PN F+ QL
Sbjct: 135 VIAYLMMRQKMDVKSALSIV-RQNREIGPNDGFLAQL 170
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 79.7 bits (195), Expect = 4e-15
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 5/141 (3%)
Query: 247 QILPYLYLGCAKDS--TNLDVLGKYGIKYILNVTPNLPNAF---EHGGEFTYKQIPISDH 301
+ILP L+LG + + L VL K+GI +I+ + N+ F F Y + I+D+
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 302 WSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFV 361
+N+ +FFP FID + VLVH AGISRS +AY+M+ + DA+ +V
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 362 KRKKSNISPNFNFMGQLLDFE 382
+ ++ I+PN F+ QL ++E
Sbjct: 151 QERRFCINPNAGFVHQLQEYE 171
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 79.7 bits (195), Expect = 4e-15
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 5/141 (3%)
Query: 247 QILPYLYLGCAKDS--TNLDVLGKYGIKYILNVTPNLPNAF---EHGGEFTYKQIPISDH 301
+ILP L+LG + + L VL K+GI +I+ + N+ F F Y + I+D+
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 302 WSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFV 361
+N+ +FFP FID + VLVH AGISRS +AY+M+ + DA+ +V
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 362 KRKKSNISPNFNFMGQLLDFE 382
+ ++ I+PN F+ QL ++E
Sbjct: 151 QERRFCINPNAGFVHQLQEYE 171
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 79.7 bits (195), Expect = 4e-15
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 5/141 (3%)
Query: 247 QILPYLYLGCAKDS--TNLDVLGKYGIKYILNVTPNLPNAF---EHGGEFTYKQIPISDH 301
+ILP L+LG + + L VL K+GI +I+ + N+ F F Y + I+D+
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 302 WSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFV 361
+N+ +FFP FID + VLVH AGISRS +AY+M+ + DA+ +V
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 362 KRKKSNISPNFNFMGQLLDFE 382
+ ++ I+PN F+ QL ++E
Sbjct: 151 QERRFCINPNAGFVHQLQEYE 171
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 79.7 bits (195), Expect = 4e-15
Identities = 47/135 (34%), Positives = 72/135 (53%), Gaps = 3/135 (2%)
Query: 247 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNL 306
++LP LYLG D+ +LD LG+ I +I+++ + + + TY +IP++D +
Sbjct: 7 KVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQ---DITYLRIPVADTPEVPI 63
Query: 307 SQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKS 366
+ F E I+FI R LVHC AGISRS T+ AY+M L D + +K +
Sbjct: 64 KKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRP 123
Query: 367 NISPNFNFMGQLLDF 381
+PN F QL +F
Sbjct: 124 IANPNPGFRQQLEEF 138
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 79.3 bits (194), Expect = 6e-15
Identities = 50/162 (30%), Positives = 81/162 (50%), Gaps = 4/162 (2%)
Query: 247 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNL 306
+I P+LYLG ++ NL+ L + + +ILN+ + N + FTY + + D S L
Sbjct: 331 RIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPE--RFTYHNVRLWDEESAQL 388
Query: 307 SQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKS 366
+ E FI+ AR++ VLVHC G+SRS +AY M++ SL A V+ +
Sbjct: 389 LPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRP 448
Query: 367 NISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNH 408
PN F+ QL ++ L S +H +++ +P H
Sbjct: 449 IARPNPGFLRQLQIYQGILTASR--QSHVWEQKVGGVSPEEH 488
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 73.6 bits (179), Expect = 3e-13
Identities = 47/149 (31%), Positives = 72/149 (48%), Gaps = 4/149 (2%)
Query: 236 PVPSSQPAFP--VQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTY 293
PV QP+ QI LY+ + N +L I ++NV+ + N + Y
Sbjct: 9 PVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYE--DIQY 66
Query: 294 KQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLS 353
Q+P++D + L FF I K+ L+HC AG+SRS + +AYLM+ +S
Sbjct: 67 MQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMS 126
Query: 354 LNDAYDFVKRKKSNISPNFNFMGQLLDFE 382
L DA+ + K + I PN F QL+ +E
Sbjct: 127 LLDAHTWTKSCRPIIRPNSGFWEQLIHYE 155
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 71.2 bits (173), Expect = 2e-12
Identities = 48/156 (30%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Query: 227 SSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFE 286
SS + S G PS QI L+L + + +L I I+N + + N F
Sbjct: 6 SSFSSSQGVQQPSIYSFS--QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFF 63
Query: 287 HGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYL 346
G Y ++P++D L FF I ++ L+HC+AG+SRS ++ +AYL
Sbjct: 64 EG--IQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYL 121
Query: 347 MQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFE 382
M+ ++SL DA+ + K ++ I PN F QL+++E
Sbjct: 122 MKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYE 157
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 69.7 bits (169), Expect = 5e-12
Identities = 52/144 (36%), Positives = 76/144 (52%), Gaps = 7/144 (4%)
Query: 247 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPN----LPNAFEHGGEFTYKQIPISDHW 302
++ P LYLG + N L + GI ++LN + + P A+E G Y + D
Sbjct: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLG-IRYLGVEAHDSP 122
Query: 303 SQNLSQFFPEAISFIDEARSKKCG-VLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFV 361
+ ++S F A FI A S+ G +LVHC G+SRS T+ +AYLM +L+L +A V
Sbjct: 123 AFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKV 182
Query: 362 KRKKSNISPNFNFMGQLLDFERTL 385
K + I PN F+ QLL +R L
Sbjct: 183 KDHR-GIIPNRGFLRQLLALDRRL 205
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,980,718
Number of Sequences: 37866
Number of extensions: 931802
Number of successful extensions: 10557
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 241
Number of HSP's successfully gapped in prelim test: 155
Number of HSP's that attempted gapping in prelim test: 7054
Number of HSP's gapped (non-prelim): 2460
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.