Guide to the Human Genome
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Search of human proteins with 23397648

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23397648 phosphatidylinositol glycan anchor biosynthesis,
class O isoform 1 [Homo sapiens]
         (1089 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23397648 phosphatidylinositol glycan anchor biosynthesis, cla...  2188   0.0  
gi|38045917 phosphatidylinositol glycan anchor biosynthesis, cla...   907   0.0  
gi|187608446 phosphatidylinositol glycan anchor biosynthesis, cl...   206   7e-53
gi|187608438 phosphatidylinositol glycan anchor biosynthesis, cl...   206   7e-53
gi|6912500 phosphatidylinositol glycan anchor biosynthesis, clas...    50   2e-05
gi|29029537 phosphatidylinositol glycan anchor biosynthesis, cla...    50   2e-05
gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [...    45   3e-04
gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]          40   0.009
gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]           40   0.009
gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (p...    38   0.060
gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (...    35   0.50 
gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ...    34   0.66 
gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [...    33   1.1  
gi|156104866 acyl-Coenzyme A oxidase 3 isoform b [Homo sapiens]        33   1.5  
gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatas...    32   2.5  
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    32   3.3  
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    32   3.3  
gi|156104864 acyl-Coenzyme A oxidase 3 isoform a [Homo sapiens]        32   3.3  
gi|53831991 steryl-sulfatase precursor [Homo sapiens]                  32   4.3  
gi|27437030 colony stimulating factor 2 precursor [Homo sapiens]       32   4.3  
gi|169184624 PREDICTED: similar to synaptotagmin XV-b [Homo sapi...    32   4.3  
gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens]    32   4.3  
gi|31881740 solute carrier family 12 (potassium/chloride transpo...    32   4.3  
gi|132566680 scavenger receptor class B, member 1 isoform 2 [Hom...    30   9.5  

>gi|23397648 phosphatidylinositol glycan anchor biosynthesis, class O
            isoform 1 [Homo sapiens]
          Length = 1089

 Score = 2188 bits (5670), Expect = 0.0
 Identities = 1089/1089 (100%), Positives = 1089/1089 (100%)

Query: 1    MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA 60
            MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA
Sbjct: 1    MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA 60

Query: 61   CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL 120
            CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL
Sbjct: 61   CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL 120

Query: 121  YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD 180
            YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD
Sbjct: 121  YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD 180

Query: 181  TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK 240
            TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK
Sbjct: 181  TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK 240

Query: 241  HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL 300
            HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL
Sbjct: 241  HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL 300

Query: 301  YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA 360
            YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA
Sbjct: 301  YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA 360

Query: 361  LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT 420
            LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT
Sbjct: 361  LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT 420

Query: 421  LPTVIAELQQFLRGARAMCIESWARFSLVRMAGGTALLAASCFICLLASQWAISPGFPFC 480
            LPTVIAELQQFLRGARAMCIESWARFSLVRMAGGTALLAASCFICLLASQWAISPGFPFC
Sbjct: 421  LPTVIAELQQFLRGARAMCIESWARFSLVRMAGGTALLAASCFICLLASQWAISPGFPFC 480

Query: 481  PLLLTPVAWGLVGAIAYAGLLGTIELKLDLVLLGAVAAVSSFLPFLWKAWAGWGSKRPLA 540
            PLLLTPVAWGLVGAIAYAGLLGTIELKLDLVLLGAVAAVSSFLPFLWKAWAGWGSKRPLA
Sbjct: 481  PLLLTPVAWGLVGAIAYAGLLGTIELKLDLVLLGAVAAVSSFLPFLWKAWAGWGSKRPLA 540

Query: 541  TLFPIPGPVLLLLLFRLAVFFSDSFVVAEARATPFLLGSFILLLVVQLHWEGQLLPPKLL 600
            TLFPIPGPVLLLLLFRLAVFFSDSFVVAEARATPFLLGSFILLLVVQLHWEGQLLPPKLL
Sbjct: 541  TLFPIPGPVLLLLLFRLAVFFSDSFVVAEARATPFLLGSFILLLVVQLHWEGQLLPPKLL 600

Query: 601  TMPRLGTSATTNPPRHNGAYALRLGIGLLLCTRLAGLFHRCPEETPVCHSSPWLSPLASM 660
            TMPRLGTSATTNPPRHNGAYALRLGIGLLLCTRLAGLFHRCPEETPVCHSSPWLSPLASM
Sbjct: 601  TMPRLGTSATTNPPRHNGAYALRLGIGLLLCTRLAGLFHRCPEETPVCHSSPWLSPLASM 660

Query: 661  VGGRAKNLWYGACVAALVALLAAVRLWLRRYGNLKSPEPPMLFVRWGLPLMALGTAAYWA 720
            VGGRAKNLWYGACVAALVALLAAVRLWLRRYGNLKSPEPPMLFVRWGLPLMALGTAAYWA
Sbjct: 661  VGGRAKNLWYGACVAALVALLAAVRLWLRRYGNLKSPEPPMLFVRWGLPLMALGTAAYWA 720

Query: 721  LASGADEAPPRLRVLVSGASMVLPRAVAGLAASGLALLLWKPVTVLVKAGAGAPRTRTVL 780
            LASGADEAPPRLRVLVSGASMVLPRAVAGLAASGLALLLWKPVTVLVKAGAGAPRTRTVL
Sbjct: 721  LASGADEAPPRLRVLVSGASMVLPRAVAGLAASGLALLLWKPVTVLVKAGAGAPRTRTVL 780

Query: 781  TPFSGPPTSQADLDYVVPQIYRHMQEEFRGRLERTKSQGPLTVAAYQLGSVYSAAMVTAL 840
            TPFSGPPTSQADLDYVVPQIYRHMQEEFRGRLERTKSQGPLTVAAYQLGSVYSAAMVTAL
Sbjct: 781  TPFSGPPTSQADLDYVVPQIYRHMQEEFRGRLERTKSQGPLTVAAYQLGSVYSAAMVTAL 840

Query: 841  TLLAFPLLLLHAERISLVFLLLFLQSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMAT 900
            TLLAFPLLLLHAERISLVFLLLFLQSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMAT
Sbjct: 841  TLLAFPLLLLHAERISLVFLLLFLQSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMAT 900

Query: 901  QTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLW 960
            QTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLW
Sbjct: 901  QTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLW 960

Query: 961  PFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFIL 1020
            PFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFIL
Sbjct: 961  PFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFIL 1020

Query: 1021 GIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWF 1080
            GIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWF
Sbjct: 1021 GIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWF 1080

Query: 1081 RQLFLAQQR 1089
            RQLFLAQQR
Sbjct: 1081 RQLFLAQQR 1089


>gi|38045917 phosphatidylinositol glycan anchor biosynthesis, class
           O isoform 2 [Homo sapiens]
          Length = 672

 Score =  907 bits (2344), Expect = 0.0
 Identities = 448/448 (100%), Positives = 448/448 (100%)

Query: 1   MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA 60
           MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA
Sbjct: 1   MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA 60

Query: 61  CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL 120
           CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL
Sbjct: 61  CWMASRFSRVVLVLIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARL 120

Query: 121 YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD 180
           YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD
Sbjct: 121 YRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDD 180

Query: 181 TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK 240
           TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK
Sbjct: 181 TWKDLFPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHK 240

Query: 241 HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL 300
           HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL
Sbjct: 241 HGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL 300

Query: 301 YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA 360
           YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA
Sbjct: 301 YSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSA 360

Query: 361 LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT 420
           LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT
Sbjct: 361 LAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEAT 420

Query: 421 LPTVIAELQQFLRGARAMCIESWARFSL 448
           LPTVIAELQQFLRGARAMCIESWARFSL
Sbjct: 421 LPTVIAELQQFLRGARAMCIESWARFSL 448



 Score =  459 bits (1182), Expect = e-129
 Identities = 225/227 (99%), Positives = 225/227 (99%)

Query: 863  FLQSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAAFV 922
            F  SFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAAFV
Sbjct: 446  FSLSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAAFV 505

Query: 923  GFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADA 982
            GFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADA
Sbjct: 506  GFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADA 565

Query: 983  RVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWK 1042
            RVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWK
Sbjct: 566  RVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWK 625

Query: 1043 VFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWFRQLFLAQQR 1089
            VFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWFRQLFLAQQR
Sbjct: 626  VFAPKFIFEAVGFIVSSVGLLLGIALVMRVDGAVSSWFRQLFLAQQR 672


>gi|187608446 phosphatidylinositol glycan anchor biosynthesis, class
           G isoform 1 [Homo sapiens]
          Length = 983

 Score =  206 bits (525), Expect = 7e-53
 Identities = 135/374 (36%), Positives = 191/374 (51%), Gaps = 45/374 (12%)

Query: 20  GIALFTSGFL------LTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMASRFSRVVLV 73
           GIA+F  GF         R E        EP    S  W +   P        FS+VV+V
Sbjct: 19  GIAVFLRGFFPAPVRSSARAEHGAEPPAPEPSAGASSNWTTLPPP-------LFSKVVIV 71

Query: 74  LIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARLYRSQVDPPTTTMQ 133
           LIDALR DF               + F+   + L     ++   +  + ++  PPT TM 
Sbjct: 72  LIDALRDDFVFGSKG---------VKFMPYTTYL-----VEKGASHSFVAEAKPPTVTMP 117

Query: 134 RLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFSKA 193
           R+KAL TGSLP F+D   N  S A++ED++I+Q  +AG+R+VF GD+TW  LFP  F + 
Sbjct: 118 RIKALMTGSLPGFVDVIRNLNSPALLEDSVIRQAKAAGKRIVFYGDETWVKLFPKHFVEY 177

Query: 194 FFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLS 253
               SF V D   VDN +  HL   +  G+WD+LI H+LG+DH GH  GP+ P + +KLS
Sbjct: 178 DGTTSFFVSDYTEVDNNVTRHLDKVLKRGDWDILILHYLGLDHIGHISGPNSPLIGQKLS 237

Query: 254 QMDQVIQGLVERLEN-------DTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAV 306
           +MD V+  +   L++         LLV+ GDHGM+  G HG  S  EV+  L L S  + 
Sbjct: 238 EMDSVLMKIHTSLQSKERETPLPNLLVLCGDHGMSETGSHGASSTEEVNTPLILIS--SA 295

Query: 307 FPSTPPE--EPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQA 364
           F   P +   P+ + Q  +  TLA+ LGLPIP  ++G ++  +  G    +       Q 
Sbjct: 296 FERKPGDIRHPKHVQQTDVAATLAIALGLPIPKDSVGSLLFPVVEGRPMRE-------QL 348

Query: 365 SALHLNAQQVSRFL 378
             LHLN  Q+S+ L
Sbjct: 349 RFLHLNTVQLSKLL 362



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 13/44 (29%), Positives = 25/44 (56%)

Query: 1016 YLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSS 1059
            Y  I  I +    +  + LR HL +W VF+PK ++E +  ++++
Sbjct: 923  YALICSIPVFTYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLITA 966


>gi|187608438 phosphatidylinositol glycan anchor biosynthesis, class
           G isoform 2 [Homo sapiens]
          Length = 975

 Score =  206 bits (525), Expect = 7e-53
 Identities = 135/374 (36%), Positives = 191/374 (51%), Gaps = 45/374 (12%)

Query: 20  GIALFTSGFL------LTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMASRFSRVVLV 73
           GIA+F  GF         R E        EP    S  W +   P        FS+VV+V
Sbjct: 19  GIAVFLRGFFPAPVRSSARAEHGAEPPAPEPSAGASSNWTTLPPP-------LFSKVVIV 71

Query: 74  LIDALRFDFAQPQHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARLYRSQVDPPTTTMQ 133
           LIDALR DF               + F+   + L     ++   +  + ++  PPT TM 
Sbjct: 72  LIDALRDDFVFGSKG---------VKFMPYTTYL-----VEKGASHSFVAEAKPPTVTMP 117

Query: 134 RLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFSKA 193
           R+KAL TGSLP F+D   N  S A++ED++I+Q  +AG+R+VF GD+TW  LFP  F + 
Sbjct: 118 RIKALMTGSLPGFVDVIRNLNSPALLEDSVIRQAKAAGKRIVFYGDETWVKLFPKHFVEY 177

Query: 194 FFFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLS 253
               SF V D   VDN +  HL   +  G+WD+LI H+LG+DH GH  GP+ P + +KLS
Sbjct: 178 DGTTSFFVSDYTEVDNNVTRHLDKVLKRGDWDILILHYLGLDHIGHISGPNSPLIGQKLS 237

Query: 254 QMDQVIQGLVERLEN-------DTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAV 306
           +MD V+  +   L++         LLV+ GDHGM+  G HG  S  EV+  L L S  + 
Sbjct: 238 EMDSVLMKIHTSLQSKERETPLPNLLVLCGDHGMSETGSHGASSTEEVNTPLILIS--SA 295

Query: 307 FPSTPPE--EPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQA 364
           F   P +   P+ + Q  +  TLA+ LGLPIP  ++G ++  +  G    +       Q 
Sbjct: 296 FERKPGDIRHPKHVQQTDVAATLAIALGLPIPKDSVGSLLFPVVEGRPMRE-------QL 348

Query: 365 SALHLNAQQVSRFL 378
             LHLN  Q+S+ L
Sbjct: 349 RFLHLNTVQLSKLL 362



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 13/44 (29%), Positives = 25/44 (56%)

Query: 1016 YLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSS 1059
            Y  I  I +    +  + LR HL +W VF+PK ++E +  ++++
Sbjct: 915  YALICSIPVFTYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLITA 958


>gi|6912500 phosphatidylinositol glycan anchor biosynthesis, class N
           [Homo sapiens]
          Length = 931

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 35/171 (20%), Positives = 64/171 (37%), Gaps = 30/171 (17%)

Query: 226 VLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERL------ENDTLLVVAGDHG 279
           V   H LG+D  GH H P   +    + ++D  ++ +V         +  T  +   DHG
Sbjct: 205 VFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHG 264

Query: 280 MTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEP----------------EVIPQVSL 323
           MT  G HG     E    L  +     +P     +                   + Q  +
Sbjct: 265 MTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADI 324

Query: 324 VPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQV 374
            P +  L+G+P P  ++G +  +          +++ L +A ++  NA Q+
Sbjct: 325 APLMTSLIGVPFPLNSVGILPVDYL--------NNTDLFKAESMFTNAVQI 367


>gi|29029537 phosphatidylinositol glycan anchor biosynthesis, class
           N [Homo sapiens]
          Length = 931

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 35/171 (20%), Positives = 64/171 (37%), Gaps = 30/171 (17%)

Query: 226 VLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERL------ENDTLLVVAGDHG 279
           V   H LG+D  GH H P   +    + ++D  ++ +V         +  T  +   DHG
Sbjct: 205 VFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHG 264

Query: 280 MTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEP----------------EVIPQVSL 323
           MT  G HG     E    L  +     +P     +                   + Q  +
Sbjct: 265 MTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADI 324

Query: 324 VPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQV 374
            P +  L+G+P P  ++G +  +          +++ L +A ++  NA Q+
Sbjct: 325 APLMTSLIGVPFPLNSVGILPVDYL--------NNTDLFKAESMFTNAVQI 367


>gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7
           [Homo sapiens]
          Length = 458

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%)

Query: 225 DVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHG 279
           D++  +F   D  GH++GP  PE  + + Q+D+ +  L E +  + L     L++  DHG
Sbjct: 189 DLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHG 248

Query: 280 MTTNGDHGGD 289
           MTT     GD
Sbjct: 249 MTTVDKRAGD 258


>gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]
          Length = 888

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 5/51 (9%)

Query: 235 DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHGM 280
           D  GHK+GP  PEM   L ++D+++  L++ L+   L     ++  GDHGM
Sbjct: 312 DFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGM 362


>gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]
          Length = 863

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 5/51 (9%)

Query: 235 DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHGM 280
           D  GHK+GP  PEM   L ++D+++  L++ L+   L     ++  GDHGM
Sbjct: 312 DFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGM 362


>gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4
           (putative function) [Homo sapiens]
          Length = 453

 Score = 37.7 bits (86), Expect = 0.060
 Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 6/53 (11%)

Query: 235 DHCGHKHGPHHPE-MAKKLSQMDQVIQGLVERLE-----NDTLLVVAGDHGMT 281
           D  GHK+GP   E M++ L ++D +I  LV+RL+      +  +++  DHGMT
Sbjct: 189 DASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMT 241


>gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5
           (putative function) [Homo sapiens]
          Length = 477

 Score = 34.7 bits (78), Expect = 0.50
 Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 5/52 (9%)

Query: 235 DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLE-----NDTLLVVAGDHGMT 281
           D  GH  GP  P M   +S +D+ +  L++ L+     N   L++  DHGMT
Sbjct: 191 DDMGHHLGPDSPLMGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMT 242


>gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Homo sapiens]
          Length = 925

 Score = 34.3 bits (77), Expect = 0.66
 Identities = 43/188 (22%), Positives = 71/188 (37%), Gaps = 49/188 (26%)

Query: 128 PTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVV---------FMG 178
           PT T     ++ TG  P          SH I+++ +     +A   +          + G
Sbjct: 253 PTKTFPNHYSIVTGLYPE---------SHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKG 303

Query: 179 DDTWKDL-FPGAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSG-----------EWDV 226
           +  W    + G  S  FF+P  +V       NGI   +Y   +             +W  
Sbjct: 304 EPIWVTAKYQGLKSGTFFWPGSDVEI-----NGIFPDIYKMYNGSVPFEERILAVLQWLQ 358

Query: 227 LIA----HFLGV-----DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----L 272
           L      HF  +     D  GH +GP   E+ K L ++D ++  L++ L+   L     L
Sbjct: 359 LPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNL 418

Query: 273 VVAGDHGM 280
           ++  DHGM
Sbjct: 419 ILISDHGM 426


>gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6
           [Homo sapiens]
          Length = 440

 Score = 33.5 bits (75), Expect = 1.1
 Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 5/66 (7%)

Query: 221 SGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVA 275
           SG  D+   +   +D  GH +GP  P+    L  +D V++ + + ++   L     +++ 
Sbjct: 179 SGRADLAAIYHERIDVEGHHYGPASPQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIF 238

Query: 276 GDHGMT 281
            DHGMT
Sbjct: 239 SDHGMT 244


>gi|156104866 acyl-Coenzyme A oxidase 3 isoform b [Homo sapiens]
          Length = 624

 Score = 33.1 bits (74), Expect = 1.5
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 86  QHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARLYRSQ 124
           +H H P  PP     LG+LS+L  +  +  H A LYR++
Sbjct: 573 EHVHQPSVPPSLRAVLGRLSALYALWSLSRHAALLYRAE 611


>gi|239755573 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 (putative function)
           [Homo sapiens]
          Length = 661

 Score = 32.3 bits (72), Expect = 2.5
 Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 4/64 (6%)

Query: 223 EWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL----LVVAGDH 278
           ++D +  ++   D+ GH+  P        + Q+D+ I  LV   E  +L    +++  DH
Sbjct: 278 DFDFVTLYYRQPDNVGHRFKPEAENRKLMIQQLDRTIWYLVGATEKHSLQSPQVIITXDH 337

Query: 279 GMTT 282
           GM T
Sbjct: 338 GMMT 341


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 32.0 bits (71), Expect = 3.3
 Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 13/119 (10%)

Query: 579 SFILLLVVQLHWEG--QLLPPKLLTMPRLGTSATTNPPRHNGA----YALRLGIGLLLCT 632
           + I ++++  HW+G  Q L P L   PR    +      H+ +    +AL   +  +LC 
Sbjct: 369 NLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVNHSWSELYSFALFKAMSHMLCI 428

Query: 633 RLAGLFHRCPEETPVCHSSPWLSPLASMVGGRAKNLWYGACVAALVALLAAVRLWLRRY 691
              G   + PE      +  WL+ L+ +VG     ++ G   A + +L ++ R +  +Y
Sbjct: 429 ---GYGRQAPESM----TDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKY 480


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 32.0 bits (71), Expect = 3.3
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 17/122 (13%)

Query: 576 LLGSFILLLVVQLHWEG--QLLPPKLLTMPRLGTSATTNPPRHNG----AYALRLGIGLL 629
           L+G  +LL     HW+G  Q L P L   P     +  N   ++     +YAL   +  +
Sbjct: 421 LIGMMLLLC----HWDGCLQFLVPMLQDFPDDCWVSINNMVNNSWGKQYSYALFKAMSHM 476

Query: 630 LCTRLAGLFHRCPEETPVCHSSPWLSPLASMVGGRAKNLWYGACVAALVALLAAVRLWLR 689
           LC            + PV  S  WL+ L+ +VG     ++ G   A + +L ++ R +  
Sbjct: 477 LCIGYG-------RQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQE 529

Query: 690 RY 691
           +Y
Sbjct: 530 KY 531


>gi|156104864 acyl-Coenzyme A oxidase 3 isoform a [Homo sapiens]
          Length = 700

 Score = 32.0 bits (71), Expect = 3.3
 Identities = 15/37 (40%), Positives = 20/37 (54%)

Query: 86  QHSHVPREPPVSLPFLGKLSSLQRILEIQPHHARLYR 122
           +H H P  PP     LG+LS+L  +  +  H A LYR
Sbjct: 573 EHVHQPSVPPSLRAVLGRLSALYALWSLSRHAALLYR 609


>gi|53831991 steryl-sulfatase precursor [Homo sapiens]
          Length = 583

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 42/164 (25%), Positives = 65/164 (39%), Gaps = 24/164 (14%)

Query: 229 AHFLGVDHCGH-KHGPHHPEMAKKLSQMDQVIQGLVE-RLENDTLLVVAGDHG-----MT 281
           A F   D  G  +HG +   + +    + Q++  L E RL NDTL+    D G     ++
Sbjct: 292 ALFSSKDFAGKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVS 351

Query: 282 TNGD-HGGDS-----------ELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLAL 329
           + G+ HGG +           E  +     L  P  +      +EP     + + PT+A 
Sbjct: 352 SKGEIHGGSNGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPT--SNMDIFPTVAK 409

Query: 330 LLGLPIPFGNI--GEVMAELFSGGEDSQPHSSALAQASALHLNA 371
           L G P+P   I  G  +  L  G      H       +A +LNA
Sbjct: 410 LAGAPLPEDRIIDGRDLMPLLEGKSQRSDHEFLFHYCNA-YLNA 452


>gi|27437030 colony stimulating factor 2 precursor [Homo sapiens]
          Length = 144

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%)

Query: 862 LFLQSFLLLHLLAAGI--PVTTPGPFTVPWQAVSA 894
           ++LQS LLL  +A  I  P  +P P T PW+ V+A
Sbjct: 1   MWLQSLLLLGTVACSISAPARSPSPSTQPWEHVNA 35


>gi|169184624 PREDICTED: similar to synaptotagmin XV-b [Homo
           sapiens]
          Length = 267

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 38/121 (31%), Positives = 47/121 (38%), Gaps = 23/121 (19%)

Query: 600 LTMPRLGTSATTNPPRHNGAY---ALRLGIGLLLCTRLAGLFHRCPEETPVCHSSPWLSP 656
           L  P+LGTS+TT+ P         ALR G        LA          P C SSP    
Sbjct: 149 LPAPQLGTSSTTDRPCARPTAPRGALRDG--------LAAQPQPPRPARPACGSSPMAEQ 200

Query: 657 LASMVGGRAKNLWYGACVAALVALLAAVRLWLRRYGNLKSPEPPMLFVRWGLPLMALGTA 716
           LA ++GG    L        L+ + A+  LW R    L   E P      G P MA   A
Sbjct: 201 LALVIGGTIGGL------LLLLLIGASCCLWRRFCATLTYEELP------GTPAMATTAA 248

Query: 717 A 717
           +
Sbjct: 249 S 249


>gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens]
          Length = 550

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 34/117 (29%)

Query: 247 EMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHG-----GDSELEVSAALFLY 301
           ++ + LS +D +      +L N T++    DHG    G+HG      + ++     L  Y
Sbjct: 310 QVGRLLSALDDL------QLANSTIIAFTSDHGWAL-GEHGEWAKYSNFDVATHVPLIFY 362

Query: 302 SP----------TAVFPSTPP------------EEPEVIPQVSLVPTLALLLGLPIP 336
            P            +FP   P            +  +++  VSL PTLA L GL +P
Sbjct: 363 VPGRTASLPEAGEKLFPYLDPFDSASQLMEPGRQSMDLVELVSLFPTLAGLAGLQVP 419


>gi|31881740 solute carrier family 12 (potassium/chloride
           transporters), member 9 [Homo sapiens]
          Length = 914

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 6/89 (6%)

Query: 456 ALLAASCFICLLASQWAISPGF-PFCPLLLTPVAWGLVGAIAYAGLLGTIELKLDLVLLG 514
           AL     F  +LA    +S G  P+  +L +   WGLV  +  AG L T+   + +  L 
Sbjct: 371 ALARDDLFGVILAPAKVVSRGGNPWAAVLYS---WGLVQLVLLAGKLNTLAAVVTVFYLV 427

Query: 515 AVAAVSSFLPFLWKAWAGWGSKRPLATLF 543
           A AAV   L  L   WA   + RP  +LF
Sbjct: 428 AYAAVD--LSCLSLEWASAPNFRPTFSLF 454


>gi|132566680 scavenger receptor class B, member 1 isoform 2 [Homo
           sapiens]
          Length = 506

 Score = 30.4 bits (67), Expect = 9.5
 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 7/90 (7%)

Query: 909 QPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANT--FASHLLFAVGCPLLLLWPFLCE- 965
           +PV   + W A   G  EG    T+   L++      +A ++L A+GC LLL+ P +C+ 
Sbjct: 407 EPVVLPLLWFAES-GAMEGETLHTFYTQLVLMPKVMHYAQYVLLALGCVLLLV-PVICQI 464

Query: 966 -SQGLRKRQQPPGNEADARVRPEEEEEPLM 994
            SQG       PG  A    RP     PL+
Sbjct: 465 RSQGPEDTVSQPGLAAGPD-RPPSPYTPLL 493


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,791,364
Number of Sequences: 37866
Number of extensions: 2126091
Number of successful extensions: 7754
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 7717
Number of HSP's gapped (non-prelim): 40
length of query: 1089
length of database: 18,247,518
effective HSP length: 113
effective length of query: 976
effective length of database: 13,968,660
effective search space: 13633412160
effective search space used: 13633412160
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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