Guide to the Human Genome
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Search of human proteins with 22749039

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749039 cornichon homolog 3 [Homo sapiens]
         (160 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749039 cornichon homolog 3 [Homo sapiens]                        342   8e-95
gi|32698938 cornichon homolog 2 [Homo sapiens]                        285   1e-77
gi|5031639 cornichon-like [Homo sapiens]                              226   5e-60
gi|7661824 cornichon homolog 4 [Homo sapiens]                          84   7e-17
gi|211971060 G protein-coupled receptor 107 isoform 2 [Homo sapi...    32   0.23 
gi|160707881 formin 2 [Homo sapiens]                                   29   2.0  
gi|4506537 receptor-interacting serine-threonine kinase 2 [Homo ...    28   2.6  
gi|211971058 G protein-coupled receptor 107 isoform 1 [Homo sapi...    28   4.4  
gi|187960045 kynurenine 3-monooxygenase [Homo sapiens]                 27   5.7  
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi...    27   9.8  
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa...    27   9.8  
gi|117320518 complement factor H-related 4 [Homo sapiens]              27   9.8  

>gi|22749039 cornichon homolog 3 [Homo sapiens]
          Length = 160

 Score =  342 bits (877), Expect = 8e-95
 Identities = 160/160 (100%), Positives = 160/160 (100%)

Query: 1   MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERI 60
           MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERI
Sbjct: 1   MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERI 60

Query: 61  CFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPP 120
           CFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPP
Sbjct: 61  CFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPP 120

Query: 121 VVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS 160
           VVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS
Sbjct: 121 VVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS 160


>gi|32698938 cornichon homolog 2 [Homo sapiens]
          Length = 160

 Score =  285 bits (729), Expect = 1e-77
 Identities = 130/159 (81%), Positives = 143/159 (89%)

Query: 1   MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERI 60
           MAFTFAAFCYML+LVLCA+LIFF IWHIIAFDELRTDFK+PIDQ NP  ARERL+NIERI
Sbjct: 1   MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERI 60

Query: 61  CFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPP 120
           C LLRKLV+PEYSIH LFC+MFLCA EW+TLGLN+PLLFYH WRYFH PAD SE+ YD  
Sbjct: 61  CCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAV 120

Query: 121 VVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVS 159
            +MNAD L+YCQKE+WCKLAFYLLSFFYYLY M+YTLVS
Sbjct: 121 SIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVS 159


>gi|5031639 cornichon-like [Homo sapiens]
          Length = 144

 Score =  226 bits (577), Expect = 5e-60
 Identities = 109/160 (68%), Positives = 120/160 (75%), Gaps = 16/160 (10%)

Query: 1   MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERI 60
           MAFTFAAFCYML+L+L AALIFFAIWHIIAFDEL+TD+K+PIDQCN              
Sbjct: 1   MAFTFAAFCYMLALLLTAALIFFAIWHIIAFDELKTDYKNPIDQCNT------------- 47

Query: 61  CFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPP 120
              L  LVLPEY IH+ FC+MFLCA EWLTLGLN+PLL YH WRY   P  S    YDP 
Sbjct: 48  ---LNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPT 104

Query: 121 VVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS 160
            +MNAD L+YCQKE WCKLAFYLL+FFYYLY MIY LVSS
Sbjct: 105 TIMNADILAYCQKEGWCKLAFYLLAFFYYLYGMIYVLVSS 144


>gi|7661824 cornichon homolog 4 [Homo sapiens]
          Length = 139

 Score = 83.6 bits (205), Expect = 7e-17
 Identities = 49/153 (32%), Positives = 79/153 (51%), Gaps = 17/153 (11%)

Query: 7   AFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLRK 66
           A  ++ SL+ C ALIF +++ II   +L         +C+ ++AR         C  L K
Sbjct: 3   AVVFVFSLLDCCALIFLSVYFIITLSDL---------ECDYINARS-------CCSKLNK 46

Query: 67  LVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPPVVMNAD 126
            V+PE   H++  ++ L +  W    LN+P+  ++ +RY   P+ +  + +DP  + N  
Sbjct: 47  WVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATWNIYRYIMVPSGNMGV-FDPTEIHNRG 105

Query: 127 TLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVS 159
            L    KEA  KL F+LL FF YLY MI  L++
Sbjct: 106 QLKSHMKEAMIKLGFHLLCFFMYLYSMILALIN 138


>gi|211971060 G protein-coupled receptor 107 isoform 2 [Homo
           sapiens]
          Length = 571

 Score = 32.0 bits (71), Expect = 0.23
 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 6/98 (6%)

Query: 10  YMLSLVLCAALIFFAIWHIIAFDEL-RTDFKSPIDQCNPVHARERLRNIERICFL-LRKL 67
           +++ L+ C A++F  +W I    E   TD K   D   P+  R  LR   RI  + L KL
Sbjct: 405 FLVDLLCCGAILFPVVWSIRHLQEASATDGKG--DSMGPLQQRANLRAGSRIAAINLAKL 462

Query: 68  VLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRY 105
            L  +    + C ++        L L VP  F   W Y
Sbjct: 463 KLFRHYYVLIVCYIYFTRIIAFLLKLAVP--FQWKWLY 498


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 28.9 bits (63), Expect = 2.0
 Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 5/40 (12%)

Query: 22   FFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERIC 61
            FF+IWH     E  +DFK    + N +  +ER++  E +C
Sbjct: 1661 FFSIWH-----EFSSDFKDFWKKENKLLLQERVKEAEEVC 1695


>gi|4506537 receptor-interacting serine-threonine kinase 2 [Homo
           sapiens]
          Length = 540

 Score = 28.5 bits (62), Expect = 2.6
 Identities = 14/44 (31%), Positives = 24/44 (54%)

Query: 54  LRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPL 97
           LR  E I FL   + L +  + S+   + LC ++ + L LN+P+
Sbjct: 294 LRTFEEITFLEAVIQLKKTKLQSVSSAIHLCDKKKMELSLNIPV 337


>gi|211971058 G protein-coupled receptor 107 isoform 1 [Homo
           sapiens]
          Length = 600

 Score = 27.7 bits (60), Expect = 4.4
 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 3/52 (5%)

Query: 10  YMLSLVLCAALIFFAIWHIIAFDEL-RTDFKSPIDQCNPVHARERLRNIERI 60
           +++ L+ C A++F  +W I    E   TD K   D   P+  R  LR   RI
Sbjct: 405 FLVDLLCCGAILFPVVWSIRHLQEASATDGKG--DSMGPLQQRANLRAGSRI 454


>gi|187960045 kynurenine 3-monooxygenase [Homo sapiens]
          Length = 486

 Score = 27.3 bits (59), Expect = 5.7
 Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 6/59 (10%)

Query: 2   AFTFAAFCYMLSLVLCAALIFFA------IWHIIAFDELRTDFKSPIDQCNPVHARERL 54
           +F F + C +L     A + FF           + FDEL   F + +  C PV +R R+
Sbjct: 292 SFHFKSHCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRI 350


>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
           sapiens]
          Length = 767

 Score = 26.6 bits (57), Expect = 9.8
 Identities = 11/22 (50%), Positives = 13/22 (59%)

Query: 107 HCPADSSELAYDPPVVMNADTL 128
           H PA     A  PPV++N DTL
Sbjct: 67  HSPAHLPNQANSPPVIVNTDTL 88


>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
           sapiens]
          Length = 721

 Score = 26.6 bits (57), Expect = 9.8
 Identities = 11/22 (50%), Positives = 13/22 (59%)

Query: 107 HCPADSSELAYDPPVVMNADTL 128
           H PA     A  PPV++N DTL
Sbjct: 24  HSPAHLPNQANSPPVIVNTDTL 45


>gi|117320518 complement factor H-related 4 [Homo sapiens]
          Length = 331

 Score = 26.6 bits (57), Expect = 9.8
 Identities = 12/31 (38%), Positives = 16/31 (51%)

Query: 103 WRYFHCPADSSELAYDPPVVMNADTLSYCQK 133
           W +F    +SSE    PP + N DT S+  K
Sbjct: 198 WSHFPTCYNSSEKCGPPPPISNGDTTSFLLK 228


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.337    0.145    0.504 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,126,199
Number of Sequences: 37866
Number of extensions: 251627
Number of successful extensions: 811
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 799
Number of HSP's gapped (non-prelim): 13
length of query: 160
length of database: 18,247,518
effective HSP length: 94
effective length of query: 66
effective length of database: 14,688,114
effective search space: 969415524
effective search space used: 969415524
T: 11
A: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.7 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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