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Search of human proteins with 226530771
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226530771 adenosine deaminase domain containing 1
(testis-specific) isoform 3 [Homo sapiens]
(558 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226530771 adenosine deaminase domain containing 1 (testis-spe... 1109 0.0
gi|21245124 adenosine deaminase domain containing 1 (testis-spec... 1109 0.0
gi|226529650 adenosine deaminase domain containing 1 (testis-spe... 1077 0.0
gi|223972690 adenosine deaminase domain containing 2 isoform 2 [... 189 8e-48
gi|223972688 adenosine deaminase domain containing 2 isoform 1 [... 187 3e-47
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 160 4e-39
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 158 1e-38
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 147 3e-35
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 147 3e-35
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 138 2e-32
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 136 4e-32
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 136 4e-32
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 134 2e-31
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 132 1e-30
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens] 55 1e-07
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 42 0.002
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 42 0.002
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 42 0.002
gi|7657625 staufen homolog 2 [Homo sapiens] 40 0.006
gi|82659089 staufen isoform a [Homo sapiens] 35 0.18
gi|82659087 staufen isoform b [Homo sapiens] 35 0.18
gi|82659085 staufen isoform a [Homo sapiens] 35 0.18
gi|82659083 staufen isoform a [Homo sapiens] 35 0.18
gi|82659091 staufen isoform c [Homo sapiens] 33 0.90
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 32 1.5
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 32 1.5
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 32 1.5
gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens] 32 1.5
gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens] 32 2.0
gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens] 32 2.0
>gi|226530771 adenosine deaminase domain containing 1
(testis-specific) isoform 3 [Homo sapiens]
Length = 558
Score = 1109 bits (2868), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP 60
MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP
Sbjct: 1 MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP 60
Query: 61 PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ 120
PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ
Sbjct: 61 PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ 120
Query: 121 YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH 180
YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH
Sbjct: 121 YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH 180
Query: 181 YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS 240
YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS
Sbjct: 181 YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS 240
Query: 241 QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ 300
QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ
Sbjct: 241 QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ 300
Query: 301 NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN 360
NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN
Sbjct: 301 NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN 360
Query: 361 RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA 420
RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA
Sbjct: 361 RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA 420
Query: 421 LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP 480
LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP
Sbjct: 421 LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP 480
Query: 481 FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ 540
FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ
Sbjct: 481 FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ 540
Query: 541 HGYGSWIVKSPCIEQFNM 558
HGYGSWIVKSPCIEQFNM
Sbjct: 541 HGYGSWIVKSPCIEQFNM 558
>gi|21245124 adenosine deaminase domain containing 1
(testis-specific) isoform 1 [Homo sapiens]
Length = 576
Score = 1109 bits (2868), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP 60
MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP
Sbjct: 19 MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP 78
Query: 61 PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ 120
PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ
Sbjct: 79 PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ 138
Query: 121 YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH 180
YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH
Sbjct: 139 YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH 198
Query: 181 YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS 240
YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS
Sbjct: 199 YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS 258
Query: 241 QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ 300
QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ
Sbjct: 259 QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ 318
Query: 301 NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN 360
NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN
Sbjct: 319 NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN 378
Query: 361 RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA 420
RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA
Sbjct: 379 RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA 438
Query: 421 LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP 480
LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP
Sbjct: 439 LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP 498
Query: 481 FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ 540
FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ
Sbjct: 499 FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ 558
Query: 541 HGYGSWIVKSPCIEQFNM 558
HGYGSWIVKSPCIEQFNM
Sbjct: 559 HGYGSWIVKSPCIEQFNM 576
>gi|226529650 adenosine deaminase domain containing 1
(testis-specific) isoform 2 [Homo sapiens]
Length = 565
Score = 1077 bits (2786), Expect = 0.0
Identities = 547/558 (98%), Positives = 547/558 (98%), Gaps = 11/558 (1%)
Query: 1 MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP 60
MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP
Sbjct: 19 MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP 78
Query: 61 PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ 120
PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ
Sbjct: 79 PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ 138
Query: 121 YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH 180
YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH
Sbjct: 139 YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH 198
Query: 181 YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS 240
YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS
Sbjct: 199 YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS 258
Query: 241 QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ 300
QDIKPDGRVLHDTHAVVTARRSLL SKNPAMMEKSIFCTEPTSNLLTLKQ
Sbjct: 259 QDIKPDGRVLHDTHAVVTARRSLL-----------SKNPAMMEKSIFCTEPTSNLLTLKQ 307
Query: 301 NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN 360
NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN
Sbjct: 308 NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN 367
Query: 361 RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA 420
RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA
Sbjct: 368 RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA 427
Query: 421 LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP 480
LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP
Sbjct: 428 LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP 487
Query: 481 FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ 540
FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ
Sbjct: 488 FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ 547
Query: 541 HGYGSWIVKSPCIEQFNM 558
HGYGSWIVKSPCIEQFNM
Sbjct: 548 HGYGSWIVKSPCIEQFNM 565
>gi|223972690 adenosine deaminase domain containing 2 isoform 2
[Homo sapiens]
Length = 583
Score = 189 bits (479), Expect = 8e-48
Identities = 155/468 (33%), Positives = 236/468 (50%), Gaps = 44/468 (9%)
Query: 107 GPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPEPRILETSGPPPF 163
GP F F A +DG+ G +K E++ AA AL + QL+ PE +TS PP
Sbjct: 140 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESP--QTSSRPP- 196
Query: 164 PAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIER 223
L+ L+ + + +E R + +V F+ L+ RS Y ++A I+ER
Sbjct: 197 ------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWACKGTVAGVILER 244
Query: 224 ----AGQH-----EVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLF 274
A H ++VA+GTG + ++ G+ LHD H +V ARR+LLR+ +RQLLL
Sbjct: 245 EIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLA 304
Query: 275 YSKNPAMMEKSIFCTEP-TSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE 333
P E+S+ +P TLK + + LY++ PKG+A+ + L P S
Sbjct: 305 TQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAAR---DIYLPPTSEGGLP 361
Query: 334 ANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVY 392
+ + L V G++ Y P + +S+SDKL RW VLG+ GALL+H + P+Y
Sbjct: 362 HSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLY 421
Query: 393 ISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 450
+S+++ D +C D L AI R +D L LP Y+ H+ P P + +
Sbjct: 422 STSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPD 480
Query: 451 -YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKE-AK 508
+ LSLNW+ GD +E+VD +G++ + + + SRLCKA+ L F+ A+ K
Sbjct: 481 TCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGPPSRLCKASFLRAFHQAARAVGK 536
Query: 509 KELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 556
LL TY AAK + YQEA+ +L L Q G G+W K P + +F
Sbjct: 537 PYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAWPSK-PLVGKF 581
>gi|223972688 adenosine deaminase domain containing 2 isoform 1
[Homo sapiens]
Length = 665
Score = 187 bits (474), Expect = 3e-47
Identities = 153/490 (31%), Positives = 240/490 (48%), Gaps = 54/490 (11%)
Query: 95 DLKETVTTGNVMGPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPE 151
+++ + +GP F F A +DG+ G +K E++ AA AL + QL+ PE
Sbjct: 200 EMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPE 259
Query: 152 PRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLK 211
+TS PP L+ L+ + + +E R + +V F+ L+ RS Y
Sbjct: 260 SP--QTSSRPP-------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWA 304
Query: 212 YSSSLAAFIIERAGQ-------------------HEVVAIGTGEYNYSQDIKPDGRVLHD 252
++A I+ER +++VA+GTG + ++ G+ LHD
Sbjct: 305 CKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHD 364
Query: 253 THAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEP-TSNLLTLKQNINICLYMNQL 311
H +V ARR+LLR+ +RQLLL P E+S+ +P TLK + + LY++
Sbjct: 365 CHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNT 424
Query: 312 PKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDK 370
PKG+A+ + L P S + + L V G++ Y P + +S+SDK
Sbjct: 425 PKGAAR---DIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDK 481
Query: 371 LTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMF 428
L RW VLG+ GALL+H + P+Y +S+++ D +C D L AI R +D L LP
Sbjct: 482 LARWAVLGLGGALLAHLVSPLYSTSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540
Query: 429 YLVNRPHISLVPSAYPLQMNLE-YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSM 487
Y+ H+ P P + + + LSLNW+ GD +E+VD +G++ + + +
Sbjct: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGP 596
Query: 488 ASRLCKAAMLSRFNLLAKE-AKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSW 546
SRLCKA+ L F+ A+ K LL TY AAK + YQEA+ +L L Q G G+W
Sbjct: 597 PSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAW 654
Query: 547 IVKSPCIEQF 556
K P + +F
Sbjct: 655 PSK-PLVGKF 663
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 160 bits (404), Expect = 4e-39
Identities = 157/527 (29%), Positives = 245/527 (46%), Gaps = 75/527 (14%)
Query: 57 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 116
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
Query: 117 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 176
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
Query: 177 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 233
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
Query: 234 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPT 292
TG + + D G L+D HA + +RRSLLR+ Y QL L Y N ++SIF
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLEL-YLNNKDDQKRSIFQKSER 431
Query: 293 SNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE---------ANEELCLHV- 342
LK+N+ LY++ P G A+I S PH E A +L +
Sbjct: 432 GGF-RLKENVQFHLYISTSPCGDARIFS-----PHEPILEEPADRHPNRKARGQLRTKIE 485
Query: 343 AVEGKIYLTVYCPK---DGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSI 396
+ EG I + DGV R+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI
Sbjct: 486 SGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSI 545
Query: 397 LIGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSL 456
++G D L A+ QR+ + LP Y +N+P +S + +A Q F S+
Sbjct: 546 ILGSLYHGD--HLSRAMYQRISN--IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SV 600
Query: 457 NWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-- 514
NW GD ++E+++ +G K + ASRLCK A+ R+ + + LL +
Sbjct: 601 NWTVGDSAIEVINATTG--------KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKI 652
Query: 515 ---GTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM 558
YH +K + YQ AK +L + + G G+W+ K +QF++
Sbjct: 653 TKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSL 699
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 158 bits (400), Expect = 1e-38
Identities = 141/470 (30%), Positives = 219/470 (46%), Gaps = 63/470 (13%)
Query: 110 FAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVV 169
F VDG ++ G G++KK +R AA+ AL EL + P G P A
Sbjct: 306 FVMAVSVDGRTFE-GSGRSKKLARGQAAQAALQELFDIQMP--------GHAPGRARRTP 356
Query: 170 LSELAYVSKVHYEGRHIQYA-KISQIVKERFNQLISNRSEYLKYSSSLAAFIIER---AG 225
+ + ++A ISQ+V ++F ++ ++ + +LA ++ + A
Sbjct: 357 MPQ--------------EFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDAR 402
Query: 226 QHEVVAIGTGEYNYS-QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEK 284
Q +VVA+ +G S + + G V++D HA V ARR+ L + Y QL L SK E+
Sbjct: 403 QAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSER 462
Query: 285 SIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKS------QLRLNPHSISAFEANEEL 338
SIF L++NI LY++ P G A++ S L + H + F +
Sbjct: 463 SIFVRLKEGGY-RLRENILFHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRT 521
Query: 339 CLH-----VAVEGKIYLTVYCPKDGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQP 390
+ V V G + + DGV ++ +MS +DK+ RW VLG+QGALLSHF++P
Sbjct: 522 KIESGEGTVPVRGPSAVQTW---DGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEP 578
Query: 391 VYISSILIGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 450
VY+ SI++ G+ T L + R++ +LP Y NRP +S V A Q
Sbjct: 579 VYLQSIVV--GSLHHTGHLARVMSHRMEG--VGQLPASYRHNRPLLSGVSDAEARQPGKS 634
Query: 451 YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKE 510
F S+NW G LEI++ +G+ + P SRLCK + +R+ L
Sbjct: 635 PPF-SMNWVVGSADLEIINATTGRRSCGGP--------SRLCKHVLSARWARLYGRLSTR 685
Query: 511 LLEAG----TYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 556
G Y AK + +YQ K +L Q+ G G+W+ K P +QF
Sbjct: 686 TPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQF 735
Score = 38.9 bits (89), Expect = 0.013
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 67 EFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLG 126
+ + K + P +AL Q ++ R L + TG V P FA V+G+ ++ G G
Sbjct: 114 QLVWKKLSWSVAPKNALVQLHEL-RPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFE-GTG 171
Query: 127 QNKKESRSNAAKLALDELLQLDEPEPRILETSGPP 161
KK+++ AA+LAL +Q L G P
Sbjct: 172 PTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGP 206
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 147 bits (371), Expect = 3e-35
Identities = 155/562 (27%), Positives = 243/562 (43%), Gaps = 105/562 (18%)
Query: 57 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 116
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
Query: 117 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 176
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
Query: 177 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 233
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
Query: 234 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPT 292
TG + + D G L+D HA + +RRSLLR+ Y QL L Y N ++SIF
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLEL-YLNNKDDQKRSIFQKSER 431
Query: 293 SNLLTLKQNINICLYMNQLP-----------------------------KGSAQIKSQLR 323
LK+N+ LY++ P GS Q +
Sbjct: 432 GGF-RLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGL 490
Query: 324 LNPHSISAFEA---NEELCLHVAVEGKIYLTVYCPK----------------DGV---NR 361
L+ S S F+ E H + + L DGV R
Sbjct: 491 LSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGER 550
Query: 362 ISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDAL 421
+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI++G D L A+ QR+ +
Sbjct: 551 LLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGD--HLSRAMYQRISN-- 606
Query: 422 TSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSPF 481
LP Y +N+P +S + +A Q F S+NW GD ++E+++ +G
Sbjct: 607 IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVNWTVGDSAIEVINATTG-------- 657
Query: 482 KSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-----GTYHAAKCMSASYQEAKCKLKS 536
K + ASRLCK A+ R+ + + LL + YH +K + YQ AK +L +
Sbjct: 658 KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFT 717
Query: 537 YLQQHGYGSWIVKSPCIEQFNM 558
+ G G+W+ K +QF++
Sbjct: 718 AFIKAGLGAWVEKPTEQDQFSL 739
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 147 bits (370), Expect = 3e-35
Identities = 150/500 (30%), Positives = 230/500 (46%), Gaps = 75/500 (15%)
Query: 57 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 116
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
Query: 117 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 176
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
Query: 177 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 233
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
Query: 234 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPT 292
TG + + D G L+D HA + +RRSLLR+ Y QL L Y N ++SIF
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLEL-YLNNKDDQKRSIFQKSER 431
Query: 293 SNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE---------ANEELCLHV- 342
LK+N+ LY++ P G A+I S PH E A +L +
Sbjct: 432 GGF-RLKENVQFHLYISTSPCGDARIFS-----PHEPILEEPADRHPNRKARGQLRTKIE 485
Query: 343 AVEGKIYLTVYCPK---DGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSI 396
+ EG I + DGV R+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI
Sbjct: 486 SGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSI 545
Query: 397 LIGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSL 456
++G D L A+ QR+ + LP Y +N+P +S + +A Q F S+
Sbjct: 546 ILGSLYHGD--HLSRAMYQRISN--IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SV 600
Query: 457 NWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-- 514
NW GD ++E+++ +G K + ASRLCK A+ R+ + + LL +
Sbjct: 601 NWTVGDSAIEVINATTG--------KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKI 652
Query: 515 ---GTYHAAKCMSASYQEAK 531
YH +K + YQ AK
Sbjct: 653 TKPNVYHESKLAAKEYQAAK 672
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 138 bits (347), Expect = 2e-32
Identities = 140/539 (25%), Positives = 238/539 (44%), Gaps = 62/539 (11%)
Query: 36 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 94
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 687 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742
Query: 95 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 154
+ K +G P F + A V G + +KK+ + AA AL L+ +E
Sbjct: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEK---- 798
Query: 155 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSS 214
AE + +EL ++ +I+ + FN L ++ L
Sbjct: 799 ----------AERMGFTELPLTGSTFHD-------QIAMLSHRCFNTLTNSFQPSLLGRK 841
Query: 215 SLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLRYFYRQL 271
LAA I+++ + VV++GTG D + G ++D HA + +RR +R+ Y +L
Sbjct: 842 ILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSEL 901
Query: 272 LLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI-------KSQLRL 324
+ + S+ + SIF L +K+ ++ LY++ P G + ++
Sbjct: 902 MKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMEST 958
Query: 325 NPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSDKLTRWE 375
FE ++ L VE G I + + DG+ R+ +MS SDK+ RW
Sbjct: 959 ESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWN 1018
Query: 376 VLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKLPMFYLV 431
VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L ++V
Sbjct: 1019 VLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGLRHPFIV 1075
Query: 432 NRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSGMSMASR 490
N P + V + + + K S+NW D LEI+DG G + + SR
Sbjct: 1076 NHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGPRNELSR 1129
Query: 491 LCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVK 549
+ K + F L + L +Y AK + Y+ AK K L+ GYG+WI K
Sbjct: 1130 VSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISK 1188
Score = 33.9 bits (76), Expect = 0.40
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 137
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
Query: 138 KLALDELLQ 146
A+ LL+
Sbjct: 563 MKAMTILLE 571
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 136 bits (343), Expect = 4e-32
Identities = 144/545 (26%), Positives = 243/545 (44%), Gaps = 48/545 (8%)
Query: 36 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 94
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 392 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 447
Query: 95 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 154
+ K +G P F + A V G + +KK+ + AA AL L+ +E R+
Sbjct: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507
Query: 155 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 208
T P A ++LS A + G + +I+ + FN L ++
Sbjct: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 566
Query: 209 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLR 265
L LAA I+++ + VV++GTG D + G ++D HA + +RR +R
Sbjct: 567 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 626
Query: 266 YFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI------- 318
+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G +
Sbjct: 627 FLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 683
Query: 319 KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSD 369
++ FE ++ L VE G I + + DG+ R+ +MS SD
Sbjct: 684 RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 743
Query: 370 KLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKL 425
K+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L
Sbjct: 744 KILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGL 800
Query: 426 PMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSG 484
++VN P + V + + + K S+NW D LEI+DG G +
Sbjct: 801 RHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGP 854
Query: 485 MSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYG 544
+ SR+ K + F L + L +Y AK + Y+ AK K L+ GYG
Sbjct: 855 RNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYG 914
Query: 545 SWIVK 549
+WI K
Sbjct: 915 NWISK 919
Score = 33.9 bits (76), Expect = 0.40
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 137
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 208 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 267
Query: 138 KLALDELLQ 146
A+ LL+
Sbjct: 268 MKAMTILLE 276
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 136 bits (343), Expect = 4e-32
Identities = 144/545 (26%), Positives = 243/545 (44%), Gaps = 48/545 (8%)
Query: 36 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 94
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 687 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742
Query: 95 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 154
+ K +G P F + A V G + +KK+ + AA AL L+ +E R+
Sbjct: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
Query: 155 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 208
T P A ++LS A + G + +I+ + FN L ++
Sbjct: 803 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 861
Query: 209 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLR 265
L LAA I+++ + VV++GTG D + G ++D HA + +RR +R
Sbjct: 862 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 921
Query: 266 YFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI------- 318
+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G +
Sbjct: 922 FLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 978
Query: 319 KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSD 369
++ FE ++ L VE G I + + DG+ R+ +MS SD
Sbjct: 979 RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 1038
Query: 370 KLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKL 425
K+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L
Sbjct: 1039 KILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGL 1095
Query: 426 PMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSG 484
++VN P + V + + + K S+NW D LEI+DG G +
Sbjct: 1096 RHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGP 1149
Query: 485 MSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYG 544
+ SR+ K + F L + L +Y AK + Y+ AK K L+ GYG
Sbjct: 1150 RNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYG 1209
Query: 545 SWIVK 549
+WI K
Sbjct: 1210 NWISK 1214
Score = 33.9 bits (76), Expect = 0.40
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 137
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
Query: 138 KLALDELLQ 146
A+ LL+
Sbjct: 563 MKAMTILLE 571
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 134 bits (337), Expect = 2e-31
Identities = 148/535 (27%), Positives = 228/535 (42%), Gaps = 105/535 (19%)
Query: 57 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 116
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
Query: 117 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 176
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
Query: 177 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 233
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
Query: 234 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPT 292
TG + + D G L+D HA + +RRSLLR+ Y QL L Y N ++SIF
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLEL-YLNNKDDQKRSIFQKSER 431
Query: 293 SNLLTLKQNINICLYMNQLP-----------------------------KGSAQIKSQLR 323
LK+N+ LY++ P GS Q +
Sbjct: 432 GGF-RLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGL 490
Query: 324 LNPHSISAFEA---NEELCLHVAVEGKIYLTVYCPK----------------DGV---NR 361
L+ S S F+ E H + + L DGV R
Sbjct: 491 LSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGER 550
Query: 362 ISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDAL 421
+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI++G D L A+ QR+ +
Sbjct: 551 LLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGD--HLSRAMYQRISN-- 606
Query: 422 TSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSPF 481
LP Y +N+P +S + +A Q F S+NW GD ++E+++ +G
Sbjct: 607 IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVNWTVGDSAIEVINATTG-------- 657
Query: 482 KSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-----GTYHAAKCMSASYQEAK 531
K + ASRLCK A+ R+ + + LL + YH +K + YQ AK
Sbjct: 658 KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 132 bits (331), Expect = 1e-30
Identities = 131/496 (26%), Positives = 215/496 (43%), Gaps = 57/496 (11%)
Query: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 137
NPV L ++A+ + K +G P F + A V G + +KK+ + AA
Sbjct: 707 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 766
Query: 138 KLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKE 197
AL L+ +E AE + +EL ++ +I+ +
Sbjct: 767 DAALRVLIGENEK--------------AERMGFTELPLTGSTFHD-------QIAMLSHR 805
Query: 198 RFNQLISNRSEYLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTH 254
FN L ++ L LAA I+++ + VV++GTG D + G ++D H
Sbjct: 806 CFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCH 865
Query: 255 AVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKG 314
A + +RR +R+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G
Sbjct: 866 AEIISRRGFIRFLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCG 922
Query: 315 SAQI-------KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN- 360
+ ++ FE ++ L VE G I + + DG+
Sbjct: 923 DGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRL 982
Query: 361 --RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIK 414
R+ +MS SDK+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + +
Sbjct: 983 GERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV- 1039
Query: 415 QRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSG 473
R A L ++VN P + V + + + K S+NW D LEI+DG G
Sbjct: 1040 TRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRG 1099
Query: 474 KITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCK 533
+ + SR+ K + F L + L +Y AK + Y+ AK
Sbjct: 1100 TV------DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNY 1153
Query: 534 LKSYLQQHGYGSWIVK 549
K L+ GYG+WI K
Sbjct: 1154 FKKGLKDMGYGNWISK 1169
Score = 33.9 bits (76), Expect = 0.40
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 137
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
Query: 138 KLALDELLQ 146
A+ LL+
Sbjct: 563 MKAMTILLE 571
>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
Length = 502
Score = 55.5 bits (132), Expect = 1e-07
Identities = 56/220 (25%), Positives = 93/220 (42%), Gaps = 33/220 (15%)
Query: 360 NRISSMSSSDKLTRWEVLGVQGALLSHFI-QPVYISSILIGD-------------GNCSD 405
+R SMS SDK+ RW VLG QGALL H + +P+Y+S+++IG G C +
Sbjct: 292 DRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGRCQN 351
Query: 406 TRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSL 465
L + L S L L + ++ L +++W+ V
Sbjct: 352 VSALPKGFGVQELKILQSDL----LFEQSRSAVQAKRADSPGRLVPCGAAISWSA--VPE 405
Query: 466 EIVDGLSGKITESSPFKS--GMSMASRLCKAAMLSRFNLLAKEAKKE-------LLEAGT 516
+ +D + + + K+ + S++ K + F L ++ + + T
Sbjct: 406 QPLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLSRIARDKWPHSLRVQKLDT 465
Query: 517 YHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 556
Y K ++SYQEA S L++ +GSWI P QF
Sbjct: 466 YQEYKEAASSYQEA----WSTLRKQVFGSWIRNPPDYHQF 501
Score = 46.6 bits (109), Expect = 6e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 228 EVVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSI 286
E+V++GTG Q ++ +G +L+D+HA V ARRS RY QL L + E SI
Sbjct: 60 EIVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQL----AATLKEDSI 115
Query: 287 FCTEPTSNLLTLKQNINICLYMNQLPKGSAQI 318
F + L++++ + + P G A I
Sbjct: 116 FVPGTQKGVWKLRRDLIFVFFSSHTPCGDASI 147
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/62 (35%), Positives = 37/62 (59%)
Query: 83 LHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALD 142
L+ + Q Q V L +E +G F F ++DG ++ G G++KKE+++ AAKLA++
Sbjct: 14 LNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73
Query: 143 EL 144
L
Sbjct: 74 IL 75
Score = 30.0 bits (66), Expect = 5.8
Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPY-FAFCAVVDGIQYKTGLGQNKKESRSNA 136
N + +++ AQ +R+ ++ ++ + V GP F + + +Y G G K+E++ A
Sbjct: 100 NYIGLINRIAQKKRLTVNYEQCAS--GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLA 157
Query: 137 AKLALDELL 145
AKLA ++L
Sbjct: 158 AKLAYLQIL 166
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/62 (35%), Positives = 37/62 (59%)
Query: 83 LHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALD 142
L+ + Q Q V L +E +G F F ++DG ++ G G++KKE+++ AAKLA++
Sbjct: 14 LNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73
Query: 143 EL 144
L
Sbjct: 74 IL 75
Score = 30.0 bits (66), Expect = 5.8
Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPY-FAFCAVVDGIQYKTGLGQNKKESRSNA 136
N + +++ AQ +R+ ++ ++ + V GP F + + +Y G G K+E++ A
Sbjct: 100 NYIGLINRIAQKKRLTVNYEQCAS--GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLA 157
Query: 137 AKLALDELL 145
AKLA ++L
Sbjct: 158 AKLAYLQIL 166
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/62 (35%), Positives = 37/62 (59%)
Query: 83 LHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALD 142
L+ + Q Q V L +E +G F F ++DG ++ G G++KKE+++ AAKLA++
Sbjct: 14 LNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73
Query: 143 EL 144
L
Sbjct: 74 IL 75
Score = 30.0 bits (66), Expect = 5.8
Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPY-FAFCAVVDGIQYKTGLGQNKKESRSNA 136
N + +++ AQ +R+ ++ ++ + V GP F + + +Y G G K+E++ A
Sbjct: 100 NYIGLINRIAQKKRLTVNYEQCAS--GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLA 157
Query: 137 AKLALDELL 145
AKLA ++L
Sbjct: 158 AKLAYLQIL 166
>gi|7657625 staufen homolog 2 [Homo sapiens]
Length = 479
Score = 40.0 bits (92), Expect = 0.006
Identities = 45/158 (28%), Positives = 67/158 (42%), Gaps = 16/158 (10%)
Query: 2 LKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPEPLLSK 49
LK+N+PV P K+ T +S+E G SK SK T E
Sbjct: 185 LKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
Query: 50 NLSSISNPVLPPKKIPKEFIM---KYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVM 106
L + P L KK PK + +Y +G +NP+S L Q Q ++ + ++ +
Sbjct: 245 PLPVVEKPKLFFKKRPKTIVKAGPEYGQG-MNPISRLAQIQQAKKEKEPDYVLLSERGMP 303
Query: 107 GPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDEL 144
V G + TG G NKK ++ NAA+ L +L
Sbjct: 304 RRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQL 341
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 35.0 bits (79), Expect = 0.18
Identities = 54/210 (25%), Positives = 81/210 (38%), Gaps = 41/210 (19%)
Query: 2 LKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE----- 44
LK+NLPV P K T + E G SK SK E
Sbjct: 113 LKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
Query: 45 PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKET 99
PL + + + P++ P+ P+ Y +G INP+S L Q Q ++ + + + T
Sbjct: 173 PLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKEPEYT 225
Query: 100 VTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETS 158
+ T + F V G G G NKK ++ NAA+ L+ IL
Sbjct: 226 LLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------ILGFK 274
Query: 159 GPPPFPAEPVVLSELAYVSKVHYEGRHIQY 188
P P +P + SE K +GR + +
Sbjct: 275 VPQAQPTKPALKSEEKTPIKKPGDGRKVTF 304
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 35.0 bits (79), Expect = 0.18
Identities = 54/210 (25%), Positives = 81/210 (38%), Gaps = 41/210 (19%)
Query: 2 LKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE----- 44
LK+NLPV P K T + E G SK SK E
Sbjct: 194 LKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
Query: 45 PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKET 99
PL + + + P++ P+ P+ Y +G INP+S L Q Q ++ + + + T
Sbjct: 254 PLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKEPEYT 306
Query: 100 VTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETS 158
+ T + F V G G G NKK ++ NAA+ L+ IL
Sbjct: 307 LLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------ILGFK 355
Query: 159 GPPPFPAEPVVLSELAYVSKVHYEGRHIQY 188
P P +P + SE K +GR + +
Sbjct: 356 VPQAQPTKPALKSEEKTPIKKPGDGRKVTF 385
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 35.0 bits (79), Expect = 0.18
Identities = 54/210 (25%), Positives = 81/210 (38%), Gaps = 41/210 (19%)
Query: 2 LKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE----- 44
LK+NLPV P K T + E G SK SK E
Sbjct: 113 LKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
Query: 45 PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKET 99
PL + + + P++ P+ P+ Y +G INP+S L Q Q ++ + + + T
Sbjct: 173 PLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKEPEYT 225
Query: 100 VTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETS 158
+ T + F V G G G NKK ++ NAA+ L+ IL
Sbjct: 226 LLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------ILGFK 274
Query: 159 GPPPFPAEPVVLSELAYVSKVHYEGRHIQY 188
P P +P + SE K +GR + +
Sbjct: 275 VPQAQPTKPALKSEEKTPIKKPGDGRKVTF 304
>gi|82659083 staufen isoform a [Homo sapiens]
Length = 496
Score = 35.0 bits (79), Expect = 0.18
Identities = 54/210 (25%), Positives = 81/210 (38%), Gaps = 41/210 (19%)
Query: 2 LKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE----- 44
LK+NLPV P K T + E G SK SK E
Sbjct: 113 LKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
Query: 45 PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKET 99
PL + + + P++ P+ P+ Y +G INP+S L Q Q ++ + + + T
Sbjct: 173 PLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKEPEYT 225
Query: 100 VTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETS 158
+ T + F V G G G NKK ++ NAA+ L+ IL
Sbjct: 226 LLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------ILGFK 274
Query: 159 GPPPFPAEPVVLSELAYVSKVHYEGRHIQY 188
P P +P + SE K +GR + +
Sbjct: 275 VPQAQPTKPALKSEEKTPIKKPGDGRKVTF 304
>gi|82659091 staufen isoform c [Homo sapiens]
Length = 502
Score = 32.7 bits (73), Expect = 0.90
Identities = 54/216 (25%), Positives = 81/216 (37%), Gaps = 47/216 (21%)
Query: 2 LKKNLPVQ---------------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFP 43
LK+NLPV P K T + E G SK SK
Sbjct: 113 LKRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLE 172
Query: 44 E-----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQ 93
E PL + + + P++ P+ P+ Y +G INP+S L Q Q ++ +
Sbjct: 173 ELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-E 225
Query: 94 LDLKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEP 152
+ + T+ T + F V G G G NKK ++ NAA+ L+
Sbjct: 226 KEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE---------- 275
Query: 153 RILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 188
IL P P +P + SE K +GR + +
Sbjct: 276 -ILGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 310
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 32.0 bits (71), Expect = 1.5
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 16/175 (9%)
Query: 3 KKNLPVQPATKTITT---PTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVL 59
KK + A K + PTG + +++ T+ P S +
Sbjct: 450 KKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAF 509
Query: 60 PPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGI 119
P ++ + K G+ NPV L++ +R L + TG F VDG
Sbjct: 510 PSDATAEQGPILTKHGK-NPVMELNE----KRRGLKYELISETGGSHDKRFVMEVEVDGQ 564
Query: 120 QYKTGLGQNKKESRSNAAKLALDEL-------LQLDEPEPRILETSGPPPFPAEP 167
+++ G G NKK +++ AA AL++L L ++ + + G P F A+P
Sbjct: 565 KFQ-GAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKP 618
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 32.0 bits (71), Expect = 1.5
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 16/175 (9%)
Query: 3 KKNLPVQPATKTITT---PTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVL 59
KK + A K + PTG + +++ T+ P S +
Sbjct: 450 KKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAF 509
Query: 60 PPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGI 119
P ++ + K G+ NPV L++ +R L + TG F VDG
Sbjct: 510 PSDATAEQGPILTKHGK-NPVMELNE----KRRGLKYELISETGGSHDKRFVMEVEVDGQ 564
Query: 120 QYKTGLGQNKKESRSNAAKLALDEL-------LQLDEPEPRILETSGPPPFPAEP 167
+++ G G NKK +++ AA AL++L L ++ + + G P F A+P
Sbjct: 565 KFQ-GAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKP 618
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 32.0 bits (71), Expect = 1.5
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 16/175 (9%)
Query: 3 KKNLPVQPATKTITT---PTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVL 59
KK + A K + PTG + +++ T+ P S +
Sbjct: 450 KKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAF 509
Query: 60 PPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGI 119
P ++ + K G+ NPV L++ +R L + TG F VDG
Sbjct: 510 PSDATAEQGPILTKHGK-NPVMELNE----KRRGLKYELISETGGSHDKRFVMEVEVDGQ 564
Query: 120 QYKTGLGQNKKESRSNAAKLALDEL-------LQLDEPEPRILETSGPPPFPAEP 167
+++ G G NKK +++ AA AL++L L ++ + + G P F A+P
Sbjct: 565 KFQ-GAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKP 618
>gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens]
Length = 1042
Score = 32.0 bits (71), Expect = 1.5
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 156 ETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVK------ERFNQLISNRSEY 209
+ G P A V L+EL + HY G Y I + +K E +LI N+S +
Sbjct: 363 KNDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQSAW 422
Query: 210 LKYSSSLAAFIIERAGQHEVVAIG 233
S+SLA+ + +G+ E G
Sbjct: 423 TSQSNSLASCLSRLSGKSETGKTG 446
>gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens]
Length = 1726
Score = 31.6 bits (70), Expect = 2.0
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 7 PVQPAT-KTITTPTGWSSESYGLSKMASKVTQVTGNFPEPL---LSKNLSSISNPVLPPK 62
P PA K +TTPT + +++ K Q TG L L + S++N PK
Sbjct: 518 PTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPK 577
Query: 63 KIPKEFIMK 71
K K+ ++K
Sbjct: 578 KSIKKLVLK 586
>gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens]
Length = 937
Score = 31.6 bits (70), Expect = 2.0
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 7 PVQPAT-KTITTPTGWSSESYGLSKMASKVTQVTGNFPEPL---LSKNLSSISNPVLPPK 62
P PA K +TTPT + +++ K Q TG L L + S++N PK
Sbjct: 535 PTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPK 594
Query: 63 KIPKEFIMK 71
K K+ ++K
Sbjct: 595 KSIKKLVLK 603
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,727,719
Number of Sequences: 37866
Number of extensions: 901788
Number of successful extensions: 2322
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2232
Number of HSP's gapped (non-prelim): 70
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.