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Search of human proteins with 226492499
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226492499 septin 12 isoform 1 [Homo sapiens]
(312 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226492499 septin 12 isoform 1 [Homo sapiens] 643 0.0
gi|226492421 septin 12 isoform 2 [Homo sapiens] 621 e-178
gi|164698504 septin 9 isoform f [Homo sapiens] 305 3e-83
gi|164698502 septin 9 isoform d [Homo sapiens] 305 3e-83
gi|164698500 septin 9 isoform e [Homo sapiens] 305 3e-83
gi|164698498 septin 9 isoform b [Homo sapiens] 305 3e-83
gi|164698496 septin 9 isoform e [Homo sapiens] 305 3e-83
gi|164698494 septin 9 isoform a [Homo sapiens] 305 3e-83
gi|116256489 septin 9 isoform c [Homo sapiens] 305 3e-83
gi|156602655 septin 3 isoform A [Homo sapiens] 302 2e-82
gi|156602653 septin 3 isoform B [Homo sapiens] 298 4e-81
gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens] 217 9e-57
gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens] 217 9e-57
gi|4758942 septin 4 isoform 1 [Homo sapiens] 201 9e-52
gi|17986247 septin 4 isoform 3 [Homo sapiens] 201 9e-52
gi|56549640 septin 2 [Homo sapiens] 193 1e-49
gi|56549638 septin 2 [Homo sapiens] 193 1e-49
gi|56549636 septin 2 [Homo sapiens] 193 1e-49
gi|4758158 septin 2 [Homo sapiens] 193 1e-49
gi|9945439 septin 5 [Homo sapiens] 190 1e-48
gi|16604248 septin 1 [Homo sapiens] 183 2e-46
gi|21361478 septin 6 isoform B [Homo sapiens] 166 2e-41
gi|22035581 septin 6 isoform D [Homo sapiens] 166 2e-41
gi|22035579 septin 6 isoform A [Homo sapiens] 166 2e-41
gi|22035577 septin 6 isoform A [Homo sapiens] 166 2e-41
gi|8922712 septin 11 [Homo sapiens] 166 2e-41
gi|149363638 septin 8 isoform c [Homo sapiens] 162 3e-40
gi|149363689 septin 8 isoform a [Homo sapiens] 162 3e-40
gi|149363661 septin 8 isoform b [Homo sapiens] 162 3e-40
gi|21945064 septin 10 isoform 1 [Homo sapiens] 160 1e-39
>gi|226492499 septin 12 isoform 1 [Homo sapiens]
Length = 312
Score = 643 bits (1658), Expect = 0.0
Identities = 312/312 (100%), Positives = 312/312 (100%)
Query: 1 MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGL 60
MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGL
Sbjct: 1 MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGL 60
Query: 61 GKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQI 120
GKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQI
Sbjct: 61 GKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQI 120
Query: 121 NNDNCLRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQM 180
NNDNCLRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQM
Sbjct: 121 NNDNCLRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQM 180
Query: 181 CFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLL 240
CFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLL
Sbjct: 181 CFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLL 240
Query: 241 RDLLIRSHLQDLKDITHNIHYENYRVIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKV 300
RDLLIRSHLQDLKDITHNIHYENYRVIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKV
Sbjct: 241 RDLLIRSHLQDLKDITHNIHYENYRVIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKV 300
Query: 301 CRGAHDDSDDEF 312
CRGAHDDSDDEF
Sbjct: 301 CRGAHDDSDDEF 312
>gi|226492421 septin 12 isoform 2 [Homo sapiens]
Length = 358
Score = 621 bits (1601), Expect = e-178
Identities = 312/358 (87%), Positives = 312/358 (87%), Gaps = 46/358 (12%)
Query: 1 MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGL 60
MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGL
Sbjct: 1 MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGL 60
Query: 61 GKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQI 120
GKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQI
Sbjct: 61 GKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQI 120
Query: 121 NNDNC----------------------------------------------LRPLDIEFL 134
NNDNC LRPLDIEFL
Sbjct: 121 NNDNCWDPILGYINEQYEQYLQEEILITRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFL 180
Query: 135 QRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSK 194
QRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSK
Sbjct: 181 QRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSK 240
Query: 195 LRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKD 254
LRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKD
Sbjct: 241 LRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKD 300
Query: 255 ITHNIHYENYRVIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKVCRGAHDDSDDEF 312
ITHNIHYENYRVIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKVCRGAHDDSDDEF
Sbjct: 301 ITHNIHYENYRVIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKVCRGAHDDSDDEF 358
>gi|164698504 septin 9 isoform f [Homo sapiens]
Length = 335
Score = 305 bits (781), Expect = 3e-83
Identities = 162/307 (52%), Positives = 207/307 (67%), Gaps = 47/307 (15%)
Query: 12 LSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFK 71
L P+S + G VGI+++L+Q++ KAMK GFEFNIMVVGQSGLGKST++NTLFK
Sbjct: 10 LKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFK 69
Query: 72 SKVW-KSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----- 125
SK+ KS P P+T+++ S+TH IEEKGV++KLTV DTPGFGD INN+NC
Sbjct: 70 SKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIM 129
Query: 126 -----------------------------------------LRPLDIEFLQRLCRTVNVV 144
LRPLDIEF++RL + VN+V
Sbjct: 130 KFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIV 189
Query: 145 PVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVV 204
PVIA+AD+LT+EER F++RI +L ++ IDVYPQ FDED D+++N K R+ IPFAVV
Sbjct: 190 PVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVV 249
Query: 205 GADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENY 264
G+D E+ VNG+ +LGRKTKWG IEVEN HCEF LRDLLIR+H+Q++KDIT +IH+E Y
Sbjct: 250 GSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAY 309
Query: 265 RVIRLNE 271
RV RLNE
Sbjct: 310 RVKRLNE 316
>gi|164698502 septin 9 isoform d [Homo sapiens]
Length = 474
Score = 305 bits (781), Expect = 3e-83
Identities = 162/307 (52%), Positives = 207/307 (67%), Gaps = 47/307 (15%)
Query: 12 LSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFK 71
L P+S + G VGI+++L+Q++ KAMK GFEFNIMVVGQSGLGKST++NTLFK
Sbjct: 149 LKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFK 208
Query: 72 SKVW-KSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----- 125
SK+ KS P P+T+++ S+TH IEEKGV++KLTV DTPGFGD INN+NC
Sbjct: 209 SKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIM 268
Query: 126 -----------------------------------------LRPLDIEFLQRLCRTVNVV 144
LRPLDIEF++RL + VN+V
Sbjct: 269 KFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIV 328
Query: 145 PVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVV 204
PVIA+AD+LT+EER F++RI +L ++ IDVYPQ FDED D+++N K R+ IPFAVV
Sbjct: 329 PVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVV 388
Query: 205 GADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENY 264
G+D E+ VNG+ +LGRKTKWG IEVEN HCEF LRDLLIR+H+Q++KDIT +IH+E Y
Sbjct: 389 GSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAY 448
Query: 265 RVIRLNE 271
RV RLNE
Sbjct: 449 RVKRLNE 455
>gi|164698500 septin 9 isoform e [Homo sapiens]
Length = 422
Score = 305 bits (781), Expect = 3e-83
Identities = 162/307 (52%), Positives = 207/307 (67%), Gaps = 47/307 (15%)
Query: 12 LSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFK 71
L P+S + G VGI+++L+Q++ KAMK GFEFNIMVVGQSGLGKST++NTLFK
Sbjct: 97 LKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFK 156
Query: 72 SKVW-KSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----- 125
SK+ KS P P+T+++ S+TH IEEKGV++KLTV DTPGFGD INN+NC
Sbjct: 157 SKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIM 216
Query: 126 -----------------------------------------LRPLDIEFLQRLCRTVNVV 144
LRPLDIEF++RL + VN+V
Sbjct: 217 KFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIV 276
Query: 145 PVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVV 204
PVIA+AD+LT+EER F++RI +L ++ IDVYPQ FDED D+++N K R+ IPFAVV
Sbjct: 277 PVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVV 336
Query: 205 GADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENY 264
G+D E+ VNG+ +LGRKTKWG IEVEN HCEF LRDLLIR+H+Q++KDIT +IH+E Y
Sbjct: 337 GSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAY 396
Query: 265 RVIRLNE 271
RV RLNE
Sbjct: 397 RVKRLNE 403
>gi|164698498 septin 9 isoform b [Homo sapiens]
Length = 579
Score = 305 bits (781), Expect = 3e-83
Identities = 162/307 (52%), Positives = 207/307 (67%), Gaps = 47/307 (15%)
Query: 12 LSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFK 71
L P+S + G VGI+++L+Q++ KAMK GFEFNIMVVGQSGLGKST++NTLFK
Sbjct: 254 LKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFK 313
Query: 72 SKVW-KSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----- 125
SK+ KS P P+T+++ S+TH IEEKGV++KLTV DTPGFGD INN+NC
Sbjct: 314 SKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIM 373
Query: 126 -----------------------------------------LRPLDIEFLQRLCRTVNVV 144
LRPLDIEF++RL + VN+V
Sbjct: 374 KFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIV 433
Query: 145 PVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVV 204
PVIA+AD+LT+EER F++RI +L ++ IDVYPQ FDED D+++N K R+ IPFAVV
Sbjct: 434 PVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVV 493
Query: 205 GADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENY 264
G+D E+ VNG+ +LGRKTKWG IEVEN HCEF LRDLLIR+H+Q++KDIT +IH+E Y
Sbjct: 494 GSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAY 553
Query: 265 RVIRLNE 271
RV RLNE
Sbjct: 554 RVKRLNE 560
>gi|164698496 septin 9 isoform e [Homo sapiens]
Length = 422
Score = 305 bits (781), Expect = 3e-83
Identities = 162/307 (52%), Positives = 207/307 (67%), Gaps = 47/307 (15%)
Query: 12 LSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFK 71
L P+S + G VGI+++L+Q++ KAMK GFEFNIMVVGQSGLGKST++NTLFK
Sbjct: 97 LKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFK 156
Query: 72 SKVW-KSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----- 125
SK+ KS P P+T+++ S+TH IEEKGV++KLTV DTPGFGD INN+NC
Sbjct: 157 SKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIM 216
Query: 126 -----------------------------------------LRPLDIEFLQRLCRTVNVV 144
LRPLDIEF++RL + VN+V
Sbjct: 217 KFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIV 276
Query: 145 PVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVV 204
PVIA+AD+LT+EER F++RI +L ++ IDVYPQ FDED D+++N K R+ IPFAVV
Sbjct: 277 PVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVV 336
Query: 205 GADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENY 264
G+D E+ VNG+ +LGRKTKWG IEVEN HCEF LRDLLIR+H+Q++KDIT +IH+E Y
Sbjct: 337 GSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAY 396
Query: 265 RVIRLNE 271
RV RLNE
Sbjct: 397 RVKRLNE 403
>gi|164698494 septin 9 isoform a [Homo sapiens]
Length = 586
Score = 305 bits (781), Expect = 3e-83
Identities = 162/307 (52%), Positives = 207/307 (67%), Gaps = 47/307 (15%)
Query: 12 LSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFK 71
L P+S + G VGI+++L+Q++ KAMK GFEFNIMVVGQSGLGKST++NTLFK
Sbjct: 261 LKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFK 320
Query: 72 SKVW-KSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----- 125
SK+ KS P P+T+++ S+TH IEEKGV++KLTV DTPGFGD INN+NC
Sbjct: 321 SKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIM 380
Query: 126 -----------------------------------------LRPLDIEFLQRLCRTVNVV 144
LRPLDIEF++RL + VN+V
Sbjct: 381 KFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIV 440
Query: 145 PVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVV 204
PVIA+AD+LT+EER F++RI +L ++ IDVYPQ FDED D+++N K R+ IPFAVV
Sbjct: 441 PVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVV 500
Query: 205 GADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENY 264
G+D E+ VNG+ +LGRKTKWG IEVEN HCEF LRDLLIR+H+Q++KDIT +IH+E Y
Sbjct: 501 GSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAY 560
Query: 265 RVIRLNE 271
RV RLNE
Sbjct: 561 RVKRLNE 567
>gi|116256489 septin 9 isoform c [Homo sapiens]
Length = 568
Score = 305 bits (781), Expect = 3e-83
Identities = 162/307 (52%), Positives = 207/307 (67%), Gaps = 47/307 (15%)
Query: 12 LSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFK 71
L P+S + G VGI+++L+Q++ KAMK GFEFNIMVVGQSGLGKST++NTLFK
Sbjct: 243 LKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFK 302
Query: 72 SKVW-KSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----- 125
SK+ KS P P+T+++ S+TH IEEKGV++KLTV DTPGFGD INN+NC
Sbjct: 303 SKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIM 362
Query: 126 -----------------------------------------LRPLDIEFLQRLCRTVNVV 144
LRPLDIEF++RL + VN+V
Sbjct: 363 KFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIV 422
Query: 145 PVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVV 204
PVIA+AD+LT+EER F++RI +L ++ IDVYPQ FDED D+++N K R+ IPFAVV
Sbjct: 423 PVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVV 482
Query: 205 GADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENY 264
G+D E+ VNG+ +LGRKTKWG IEVEN HCEF LRDLLIR+H+Q++KDIT +IH+E Y
Sbjct: 483 GSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAY 542
Query: 265 RVIRLNE 271
RV RLNE
Sbjct: 543 RVKRLNE 549
>gi|156602655 septin 3 isoform A [Homo sapiens]
Length = 358
Score = 302 bits (774), Expect = 2e-82
Identities = 160/334 (47%), Positives = 220/334 (65%), Gaps = 55/334 (16%)
Query: 8 PSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVN 67
P P + +P S ++ +LG +GI+ +++Q++ K MK GF+FNIMVVGQSGLGKST+VN
Sbjct: 23 PKPAVPMKPMSINS---NLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVN 79
Query: 68 TLFKSKVW-KSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC- 125
TLFKS+V K++ P+T+++ ++ HVIEE GVK+KLTV DTPGFGDQINN+NC
Sbjct: 80 TLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCW 139
Query: 126 ---------------------------------------------LRPLDIEFLQRLCRT 140
LRPLD+EF++ L +
Sbjct: 140 EPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKV 199
Query: 141 VNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLR-DRI 199
VN++PVIA+AD++T+EE+ F++R+++ L + I+ YPQ FDED+ DK N K+R + +
Sbjct: 200 VNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESM 259
Query: 200 PFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNI 259
PFAVVG+D+E+ VNG+ VLGRKT WGIIEVEN+ HCEF LLRD +IR+HLQDLK++THNI
Sbjct: 260 PFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNI 319
Query: 260 HYENYRVIRLNESHLLPRGPGWVNL----APASP 289
HYE YR RLN++ LP G G + PA+P
Sbjct: 320 HYETYRAKRLNDNGGLPPGEGLLGTVLPPVPATP 353
>gi|156602653 septin 3 isoform B [Homo sapiens]
Length = 350
Score = 298 bits (763), Expect = 4e-81
Identities = 155/317 (48%), Positives = 213/317 (67%), Gaps = 51/317 (16%)
Query: 8 PSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVN 67
P P + +P S ++ +LG +GI+ +++Q++ K MK GF+FNIMVVGQSGLGKST+VN
Sbjct: 23 PKPAVPMKPMSINS---NLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVN 79
Query: 68 TLFKSKVW-KSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC- 125
TLFKS+V K++ P+T+++ ++ HVIEE GVK+KLTV DTPGFGDQINN+NC
Sbjct: 80 TLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCW 139
Query: 126 ---------------------------------------------LRPLDIEFLQRLCRT 140
LRPLD+EF++ L +
Sbjct: 140 EPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKV 199
Query: 141 VNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLR-DRI 199
VN++PVIA+AD++T+EE+ F++R+++ L + I+ YPQ FDED+ DK N K+R + +
Sbjct: 200 VNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESM 259
Query: 200 PFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNI 259
PFAVVG+D+E+ VNG+ VLGRKT WGIIEVEN+ HCEF LLRD +IR+HLQDLK++THNI
Sbjct: 260 PFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNI 319
Query: 260 HYENYRVIRLNESHLLP 276
HYE YR RLN++ LP
Sbjct: 320 HYETYRAKRLNDNGGLP 336
>gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens]
Length = 437
Score = 217 bits (553), Expect = 9e-57
Identities = 115/287 (40%), Positives = 176/287 (61%), Gaps = 46/287 (16%)
Query: 28 GPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVPTP 87
G VG + +Q+ K++K GFEF +MVVG+SGLGKST++N+LF + ++ PG
Sbjct: 29 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHRIK 88
Query: 88 QTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC---------------------- 125
+T+Q+ +I+E GV+L LT+ DTPGFGD ++N NC
Sbjct: 89 KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 148
Query: 126 -----------------------LRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFR 162
L+PLDIEF++RL VN++P+IA+AD+LT EE + F+
Sbjct: 149 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 208
Query: 163 RRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGRKT 222
++I + ++ H I +Y D++ +K++ K++DR+P AVVG++ VNG+ V GR+
Sbjct: 209 KQIMKEIQEHKIKIYEFPETDDEEENKLVK-KIKDRLPLAVVGSNTIIEVNGKRVRGRQY 267
Query: 223 KWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRL 269
WG+ EVEN HC+F +LR++LIR+H+QDLKD+T+N+HYENYR +L
Sbjct: 268 PWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKL 314
>gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens]
Length = 436
Score = 217 bits (553), Expect = 9e-57
Identities = 115/287 (40%), Positives = 176/287 (61%), Gaps = 46/287 (16%)
Query: 28 GPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVPTP 87
G VG + +Q+ K++K GFEF +MVVG+SGLGKST++N+LF + ++ PG
Sbjct: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHRIK 87
Query: 88 QTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC---------------------- 125
+T+Q+ +I+E GV+L LT+ DTPGFGD ++N NC
Sbjct: 88 KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 147
Query: 126 -----------------------LRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFR 162
L+PLDIEF++RL VN++P+IA+AD+LT EE + F+
Sbjct: 148 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 207
Query: 163 RRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGRKT 222
++I + ++ H I +Y D++ +K++ K++DR+P AVVG++ VNG+ V GR+
Sbjct: 208 KQIMKEIQEHKIKIYEFPETDDEEENKLVK-KIKDRLPLAVVGSNTIIEVNGKRVRGRQY 266
Query: 223 KWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRL 269
WG+ EVEN HC+F +LR++LIR+H+QDLKD+T+N+HYENYR +L
Sbjct: 267 PWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKL 313
>gi|4758942 septin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 201 bits (510), Expect = 9e-52
Identities = 129/360 (35%), Positives = 186/360 (51%), Gaps = 62/360 (17%)
Query: 1 MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGL 60
+ P R SP P S E VG + +Q+ K++K GF+F +MV G+SGL
Sbjct: 99 LSPSARPRSPWGKLDPYDSSEDDKEY---VGFATLPNQVHRKSVKKGFDFTLMVAGESGL 155
Query: 61 GKSTMVNTLFKSKVWKSNPP-GLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQ 119
GKST+VN+LF + +++ G QT+++ IEEKGV+L+LT+ DTPGFGD
Sbjct: 156 GKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDA 215
Query: 120 INNDNC---------------------------------------------LRPLDIEFL 134
+NN C LRPLD+EF+
Sbjct: 216 VNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFM 275
Query: 135 QRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVY--PQMCFDEDINDKILN 192
+ L + VN+VP++A+AD+LT E + +R+I++ + I +Y P DED + K+ +
Sbjct: 276 KALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQD 335
Query: 193 SKLRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDL 252
L++ IPFAV+G++ GR V GR WGI+EVEN HC+F LR +L+R+H+QDL
Sbjct: 336 QALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDL 395
Query: 253 KDITHNIHYENYR----------VIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKVCR 302
KD+T HYENYR V++ + L R G PA P T P T K+ R
Sbjct: 396 KDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPG-TDPETEKLIR 454
>gi|17986247 septin 4 isoform 3 [Homo sapiens]
Length = 459
Score = 201 bits (510), Expect = 9e-52
Identities = 129/360 (35%), Positives = 186/360 (51%), Gaps = 62/360 (17%)
Query: 1 MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGL 60
+ P R SP P S E VG + +Q+ K++K GF+F +MV G+SGL
Sbjct: 80 LSPSARPRSPWGKLDPYDSSEDDKEY---VGFATLPNQVHRKSVKKGFDFTLMVAGESGL 136
Query: 61 GKSTMVNTLFKSKVWKSNPP-GLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQ 119
GKST+VN+LF + +++ G QT+++ IEEKGV+L+LT+ DTPGFGD
Sbjct: 137 GKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDA 196
Query: 120 INNDNC---------------------------------------------LRPLDIEFL 134
+NN C LRPLD+EF+
Sbjct: 197 VNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFM 256
Query: 135 QRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVY--PQMCFDEDINDKILN 192
+ L + VN+VP++A+AD+LT E + +R+I++ + I +Y P DED + K+ +
Sbjct: 257 KALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQD 316
Query: 193 SKLRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDL 252
L++ IPFAV+G++ GR V GR WGI+EVEN HC+F LR +L+R+H+QDL
Sbjct: 317 QALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDL 376
Query: 253 KDITHNIHYENYR----------VIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKVCR 302
KD+T HYENYR V++ + L R G PA P T P T K+ R
Sbjct: 377 KDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPG-TDPETEKLIR 435
>gi|56549640 septin 2 [Homo sapiens]
Length = 361
Score = 193 bits (491), Expect = 1e-49
Identities = 116/300 (38%), Positives = 170/300 (56%), Gaps = 54/300 (18%)
Query: 18 SPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKS 77
+P TP G VG + +Q+ K++K GFEF +MVVG+SGLGKST++N+LF + ++
Sbjct: 11 NPETP-----GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPE 65
Query: 78 NP-PGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----------- 125
PG +T+Q+ + T IEE+GVKL+LTV DTPG+GD IN +C
Sbjct: 66 RVIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQ 125
Query: 126 ----------------------------------LRPLDIEFLQRLCRTVNVVPVIARAD 151
L+PLD+ F++ + VN+VPVIA+AD
Sbjct: 126 FERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKAD 185
Query: 152 SLTMEEREAFRRRIQQNLRTHCIDVY--PQMCFDEDINDKILNSKLRDRIPFAVVGADQE 209
+LT++ERE ++RI + H I +Y P DED + K L+ IPF+VVG++Q
Sbjct: 186 TLTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQL 245
Query: 210 HLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRL 269
G+ V GR WG++EVEN H +F LR +LI +H+QDL+++T ++HYEN+R RL
Sbjct: 246 IEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERL 304
>gi|56549638 septin 2 [Homo sapiens]
Length = 361
Score = 193 bits (491), Expect = 1e-49
Identities = 116/300 (38%), Positives = 170/300 (56%), Gaps = 54/300 (18%)
Query: 18 SPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKS 77
+P TP G VG + +Q+ K++K GFEF +MVVG+SGLGKST++N+LF + ++
Sbjct: 11 NPETP-----GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPE 65
Query: 78 NP-PGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----------- 125
PG +T+Q+ + T IEE+GVKL+LTV DTPG+GD IN +C
Sbjct: 66 RVIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQ 125
Query: 126 ----------------------------------LRPLDIEFLQRLCRTVNVVPVIARAD 151
L+PLD+ F++ + VN+VPVIA+AD
Sbjct: 126 FERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKAD 185
Query: 152 SLTMEEREAFRRRIQQNLRTHCIDVY--PQMCFDEDINDKILNSKLRDRIPFAVVGADQE 209
+LT++ERE ++RI + H I +Y P DED + K L+ IPF+VVG++Q
Sbjct: 186 TLTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQL 245
Query: 210 HLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRL 269
G+ V GR WG++EVEN H +F LR +LI +H+QDL+++T ++HYEN+R RL
Sbjct: 246 IEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERL 304
>gi|56549636 septin 2 [Homo sapiens]
Length = 361
Score = 193 bits (491), Expect = 1e-49
Identities = 116/300 (38%), Positives = 170/300 (56%), Gaps = 54/300 (18%)
Query: 18 SPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKS 77
+P TP G VG + +Q+ K++K GFEF +MVVG+SGLGKST++N+LF + ++
Sbjct: 11 NPETP-----GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPE 65
Query: 78 NP-PGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----------- 125
PG +T+Q+ + T IEE+GVKL+LTV DTPG+GD IN +C
Sbjct: 66 RVIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQ 125
Query: 126 ----------------------------------LRPLDIEFLQRLCRTVNVVPVIARAD 151
L+PLD+ F++ + VN+VPVIA+AD
Sbjct: 126 FERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKAD 185
Query: 152 SLTMEEREAFRRRIQQNLRTHCIDVY--PQMCFDEDINDKILNSKLRDRIPFAVVGADQE 209
+LT++ERE ++RI + H I +Y P DED + K L+ IPF+VVG++Q
Sbjct: 186 TLTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQL 245
Query: 210 HLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRL 269
G+ V GR WG++EVEN H +F LR +LI +H+QDL+++T ++HYEN+R RL
Sbjct: 246 IEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERL 304
>gi|4758158 septin 2 [Homo sapiens]
Length = 361
Score = 193 bits (491), Expect = 1e-49
Identities = 116/300 (38%), Positives = 170/300 (56%), Gaps = 54/300 (18%)
Query: 18 SPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKS 77
+P TP G VG + +Q+ K++K GFEF +MVVG+SGLGKST++N+LF + ++
Sbjct: 11 NPETP-----GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPE 65
Query: 78 NP-PGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----------- 125
PG +T+Q+ + T IEE+GVKL+LTV DTPG+GD IN +C
Sbjct: 66 RVIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQ 125
Query: 126 ----------------------------------LRPLDIEFLQRLCRTVNVVPVIARAD 151
L+PLD+ F++ + VN+VPVIA+AD
Sbjct: 126 FERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKAD 185
Query: 152 SLTMEEREAFRRRIQQNLRTHCIDVY--PQMCFDEDINDKILNSKLRDRIPFAVVGADQE 209
+LT++ERE ++RI + H I +Y P DED + K L+ IPF+VVG++Q
Sbjct: 186 TLTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQL 245
Query: 210 HLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRL 269
G+ V GR WG++EVEN H +F LR +LI +H+QDL+++T ++HYEN+R RL
Sbjct: 246 IEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERL 304
>gi|9945439 septin 5 [Homo sapiens]
Length = 369
Score = 190 bits (483), Expect = 1e-48
Identities = 110/284 (38%), Positives = 159/284 (55%), Gaps = 48/284 (16%)
Query: 30 VGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPP-GLGVPTPQ 88
VG + +Q+ K++K GF+F +MV G+SGLGKST+V++LF + ++K Q
Sbjct: 25 VGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQ 84
Query: 89 TLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----------------------- 125
T+++ T IEEKGVKLKLT+ DTPGFGD +NN C
Sbjct: 85 TVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLN 144
Query: 126 ----------------------LRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFRR 163
LRP+D+ F++ L VN+VP+IA+AD L E +
Sbjct: 145 RKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKE 204
Query: 164 RIQQNLRTHCIDVY--PQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGRK 221
RI++ + I VY P+ DED + K + +L++ PFAV+G++ G+ V GR
Sbjct: 205 RIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRL 264
Query: 222 TKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYR 265
WGI+EVEN AHC+F LR++LIR+H+ DLKD+T ++HYENYR
Sbjct: 265 YPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYR 308
>gi|16604248 septin 1 [Homo sapiens]
Length = 367
Score = 183 bits (464), Expect = 2e-46
Identities = 106/285 (37%), Positives = 162/285 (56%), Gaps = 49/285 (17%)
Query: 30 VGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNP-PGLGVPTPQ 88
VG A+ +QL K++K GF+F +MV G+SGLGKST++N+LF + +++ P Q
Sbjct: 6 VGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLTQ 65
Query: 89 TLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNC----------------------- 125
TL + IEE GVK+KLT+ DTPGFGD ++ +C
Sbjct: 66 TLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGLN 125
Query: 126 ----------------------LRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFRR 163
LRPLD+ FL+ + VN++PVI +AD+L +E +A ++
Sbjct: 126 RKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALKQ 185
Query: 164 RIQQNLRTHCIDVY--PQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNG-RCVLGR 220
+I+ L+ I +Y P+ DED + K ++++++ IPFAVVG+ + G R V GR
Sbjct: 186 KIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRGR 245
Query: 221 KTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYR 265
+ WG +EVEN HC+F LR +L+++HLQDLK++TH++ YE YR
Sbjct: 246 RYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYR 290
>gi|21361478 septin 6 isoform B [Homo sapiens]
Length = 434
Score = 166 bits (421), Expect = 2e-41
Identities = 95/293 (32%), Positives = 159/293 (54%), Gaps = 53/293 (18%)
Query: 26 MLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVP 85
+ G VG +++ DQL K++ GF FNI+ VG++GLGKST+++TLF +K ++ P
Sbjct: 19 LAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTK-FEGEP---ATH 74
Query: 86 TPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCLRP----------------- 128
T +QL S T+ ++E V+LKLT+ T GFGDQIN ++ +P
Sbjct: 75 TQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEEL 134
Query: 129 ------------------------------LDIEFLQRLCRTVNVVPVIARADSLTMEER 158
LD+ +++L VN++P+IA+AD+++ E
Sbjct: 135 KIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSEL 194
Query: 159 EAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVL 218
F+ +I L ++ + +Y DE + + +N + +PFAV+G+ +E + + +
Sbjct: 195 TKFKIKITSELVSNGVQIYQFPTDDESVAE--INGTMNAHLPFAVIGSTEELKIGNKMMR 252
Query: 219 GRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRLNE 271
R+ WG ++VEN AHC+F LR++LIR +++DL++ TH HYE YR +L E
Sbjct: 253 ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEE 305
>gi|22035581 septin 6 isoform D [Homo sapiens]
Length = 429
Score = 166 bits (421), Expect = 2e-41
Identities = 95/293 (32%), Positives = 159/293 (54%), Gaps = 53/293 (18%)
Query: 26 MLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVP 85
+ G VG +++ DQL K++ GF FNI+ VG++GLGKST+++TLF +K ++ P
Sbjct: 19 LAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTK-FEGEP---ATH 74
Query: 86 TPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCLRP----------------- 128
T +QL S T+ ++E V+LKLT+ T GFGDQIN ++ +P
Sbjct: 75 TQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEEL 134
Query: 129 ------------------------------LDIEFLQRLCRTVNVVPVIARADSLTMEER 158
LD+ +++L VN++P+IA+AD+++ E
Sbjct: 135 KIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSEL 194
Query: 159 EAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVL 218
F+ +I L ++ + +Y DE + + +N + +PFAV+G+ +E + + +
Sbjct: 195 TKFKIKITSELVSNGVQIYQFPTDDESVAE--INGTMNAHLPFAVIGSTEELKIGNKMMR 252
Query: 219 GRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRLNE 271
R+ WG ++VEN AHC+F LR++LIR +++DL++ TH HYE YR +L E
Sbjct: 253 ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEE 305
>gi|22035579 septin 6 isoform A [Homo sapiens]
Length = 427
Score = 166 bits (421), Expect = 2e-41
Identities = 95/293 (32%), Positives = 159/293 (54%), Gaps = 53/293 (18%)
Query: 26 MLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVP 85
+ G VG +++ DQL K++ GF FNI+ VG++GLGKST+++TLF +K ++ P
Sbjct: 19 LAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTK-FEGEP---ATH 74
Query: 86 TPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCLRP----------------- 128
T +QL S T+ ++E V+LKLT+ T GFGDQIN ++ +P
Sbjct: 75 TQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEEL 134
Query: 129 ------------------------------LDIEFLQRLCRTVNVVPVIARADSLTMEER 158
LD+ +++L VN++P+IA+AD+++ E
Sbjct: 135 KIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSEL 194
Query: 159 EAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVL 218
F+ +I L ++ + +Y DE + + +N + +PFAV+G+ +E + + +
Sbjct: 195 TKFKIKITSELVSNGVQIYQFPTDDESVAE--INGTMNAHLPFAVIGSTEELKIGNKMMR 252
Query: 219 GRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRLNE 271
R+ WG ++VEN AHC+F LR++LIR +++DL++ TH HYE YR +L E
Sbjct: 253 ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEE 305
>gi|22035577 septin 6 isoform A [Homo sapiens]
Length = 427
Score = 166 bits (421), Expect = 2e-41
Identities = 95/293 (32%), Positives = 159/293 (54%), Gaps = 53/293 (18%)
Query: 26 MLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVP 85
+ G VG +++ DQL K++ GF FNI+ VG++GLGKST+++TLF +K ++ P
Sbjct: 19 LAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTK-FEGEP---ATH 74
Query: 86 TPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCLRP----------------- 128
T +QL S T+ ++E V+LKLT+ T GFGDQIN ++ +P
Sbjct: 75 TQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEEL 134
Query: 129 ------------------------------LDIEFLQRLCRTVNVVPVIARADSLTMEER 158
LD+ +++L VN++P+IA+AD+++ E
Sbjct: 135 KIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSEL 194
Query: 159 EAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVL 218
F+ +I L ++ + +Y DE + + +N + +PFAV+G+ +E + + +
Sbjct: 195 TKFKIKITSELVSNGVQIYQFPTDDESVAE--INGTMNAHLPFAVIGSTEELKIGNKMMR 252
Query: 219 GRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRLNE 271
R+ WG ++VEN AHC+F LR++LIR +++DL++ TH HYE YR +L E
Sbjct: 253 ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEE 305
>gi|8922712 septin 11 [Homo sapiens]
Length = 429
Score = 166 bits (420), Expect = 2e-41
Identities = 95/304 (31%), Positives = 164/304 (53%), Gaps = 53/304 (17%)
Query: 15 QPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKV 74
+PS+ + G VG +++ DQL K+ GF FNI+ VG++G+GKST+++TLF +K
Sbjct: 7 RPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTK- 65
Query: 75 WKSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCLRP------ 128
++S+P P ++L + ++ ++E V+LKLT+ DT GFGDQIN D+ +P
Sbjct: 66 FESDPATHNEPG---VRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYID 122
Query: 129 -----------------------------------------LDIEFLQRLCRTVNVVPVI 147
LD+ +++L VN++P+I
Sbjct: 123 AQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPII 182
Query: 148 ARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGAD 207
A+AD++ E F+ +I L ++ + +Y +E + + +N+ + +PFAVVG+
Sbjct: 183 AKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAE--INATMSVHLPFAVVGST 240
Query: 208 QEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVI 267
+E + + R+ WG+++VEN HC+F LR++LIR +++DL++ TH HYE YR
Sbjct: 241 EEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRC 300
Query: 268 RLNE 271
+L E
Sbjct: 301 KLEE 304
>gi|149363638 septin 8 isoform c [Homo sapiens]
Length = 442
Score = 162 bits (411), Expect = 3e-40
Identities = 95/302 (31%), Positives = 156/302 (51%), Gaps = 53/302 (17%)
Query: 17 SSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWK 76
+ P + G VG +++ DQL K++ GF FNI+ VG++G+GKST++NTLF +
Sbjct: 12 AEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFET 71
Query: 77 SNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCLRP-------- 128
++L T+ ++E V+LKLT+ D GFGDQIN D RP
Sbjct: 72 EEASH----HEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQ 127
Query: 129 ---------------------------------------LDIEFLQRLCRTVNVVPVIAR 149
LD+ +++L VN++P+IA+
Sbjct: 128 FENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAK 187
Query: 150 ADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQE 209
AD+++ E F+ +I L ++ + +Y DE + + +N+ + +PFAVVG+ +E
Sbjct: 188 ADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAE--INAVMNAHLPFAVVGSTEE 245
Query: 210 HLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRL 269
V + V R+ WG+++VEN HC+F LR++LIR +++DL++ TH+ HYE YR +L
Sbjct: 246 VKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKL 305
Query: 270 NE 271
E
Sbjct: 306 EE 307
>gi|149363689 septin 8 isoform a [Homo sapiens]
Length = 483
Score = 162 bits (411), Expect = 3e-40
Identities = 95/302 (31%), Positives = 156/302 (51%), Gaps = 53/302 (17%)
Query: 17 SSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWK 76
+ P + G VG +++ DQL K++ GF FNI+ VG++G+GKST++NTLF +
Sbjct: 12 AEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFET 71
Query: 77 SNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCLRP-------- 128
++L T+ ++E V+LKLT+ D GFGDQIN D RP
Sbjct: 72 EEASH----HEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQ 127
Query: 129 ---------------------------------------LDIEFLQRLCRTVNVVPVIAR 149
LD+ +++L VN++P+IA+
Sbjct: 128 FENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAK 187
Query: 150 ADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQE 209
AD+++ E F+ +I L ++ + +Y DE + + +N+ + +PFAVVG+ +E
Sbjct: 188 ADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAE--INAVMNAHLPFAVVGSTEE 245
Query: 210 HLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRL 269
V + V R+ WG+++VEN HC+F LR++LIR +++DL++ TH+ HYE YR +L
Sbjct: 246 VKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKL 305
Query: 270 NE 271
E
Sbjct: 306 EE 307
>gi|149363661 septin 8 isoform b [Homo sapiens]
Length = 429
Score = 162 bits (411), Expect = 3e-40
Identities = 95/302 (31%), Positives = 156/302 (51%), Gaps = 53/302 (17%)
Query: 17 SSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWK 76
+ P + G VG +++ DQL K++ GF FNI+ VG++G+GKST++NTLF +
Sbjct: 12 AEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFET 71
Query: 77 SNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCLRP-------- 128
++L T+ ++E V+LKLT+ D GFGDQIN D RP
Sbjct: 72 EEASH----HEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQ 127
Query: 129 ---------------------------------------LDIEFLQRLCRTVNVVPVIAR 149
LD+ +++L VN++P+IA+
Sbjct: 128 FENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAK 187
Query: 150 ADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQE 209
AD+++ E F+ +I L ++ + +Y DE + + +N+ + +PFAVVG+ +E
Sbjct: 188 ADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAE--INAVMNAHLPFAVVGSTEE 245
Query: 210 HLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRL 269
V + V R+ WG+++VEN HC+F LR++LIR +++DL++ TH+ HYE YR +L
Sbjct: 246 VKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKL 305
Query: 270 NE 271
E
Sbjct: 306 EE 307
>gi|21945064 septin 10 isoform 1 [Homo sapiens]
Length = 454
Score = 160 bits (405), Expect = 1e-39
Identities = 102/322 (31%), Positives = 169/322 (52%), Gaps = 59/322 (18%)
Query: 11 CLSSQPSSPSTPPCE------MLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKST 64
C+SSQ S E M G VG E++ DQL ++++ GF FNI+ VG++G+GKST
Sbjct: 22 CMSSQGSDDEQIKRENIRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKST 81
Query: 65 MVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDN 124
+++TLF + ++ P ++L + T+ ++E V+LKLT+ +T GFGDQIN +
Sbjct: 82 LIDTLFNTN-FEDYESSHFCPN---VKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEE 137
Query: 125 CLRP-----------------------------------------------LDIEFLQRL 137
+P LD+ ++ L
Sbjct: 138 SYQPIVDYIDAQFEAYLQEELKIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNL 197
Query: 138 CRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRD 197
VN++PVIA+AD+++ E + F+ ++ L ++ + +Y Q D+D K+ N+ +
Sbjct: 198 DSKVNIIPVIAKADTVSKTELQKFKIKLMSELVSNGVQIY-QFPTDDDTIAKV-NAAMNG 255
Query: 198 RIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITH 257
++PFAVVG+ E V + V R+ WG+++VEN HC+F LR++LI ++++DL++ TH
Sbjct: 256 QLPFAVVGSMDEVKVGNKMVKARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTH 315
Query: 258 NIHYENYRVIRLNESHLLPRGP 279
HYE YR +L E GP
Sbjct: 316 TRHYELYRRCKLEEMGFTDVGP 337
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,745,453
Number of Sequences: 37866
Number of extensions: 646844
Number of successful extensions: 2504
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2369
Number of HSP's gapped (non-prelim): 104
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.