Guide to the Human Genome
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Search of human proteins with 226246682

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226246682 prostaglandin reductase 2 [Homo sapiens]
         (351 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226246682 prostaglandin reductase 2 [Homo sapiens]                 714   0.0  
gi|226246680 prostaglandin reductase 2 [Homo sapiens]                 714   0.0  
gi|22748929 prostaglandin reductase 2 [Homo sapiens]                  714   0.0  
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]       203   2e-52
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]       203   2e-52
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]       166   3e-41
gi|28557745 zinc binding alcohol dehydrogenase domain containing...    91   2e-18
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa...    40   0.002
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]       36   0.059
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]       36   0.059
gi|18379349 vesicle amine transport protein 1 [Homo sapiens]           34   0.22 
gi|37620210 hypothetical protein LOC116228 [Homo sapiens]              32   1.1  
gi|23510356 RIO kinase 1 isoform 1 [Homo sapiens]                      31   1.5  
gi|23510358 RIO kinase 1 isoform 2 [Homo sapiens]                      31   1.5  
gi|31543093 galactosidase, beta 1-like 2 [Homo sapiens]                31   1.9  
gi|221554518 cyclin L2 isoform D [Homo sapiens]                        31   1.9  
gi|221554516 cyclin L2 isoform C [Homo sapiens]                        31   1.9  
gi|88758578 cyclin L2 isoform B [Homo sapiens]                         31   1.9  
gi|88758580 cyclin L2 isoform A [Homo sapiens]                         31   1.9  
gi|49640014 ubiquitin associated and SH3 domain containing, A sh...    28   9.4  
gi|9507221 ubiquitin associated and SH3 domain containing, A lon...    28   9.4  

>gi|226246682 prostaglandin reductase 2 [Homo sapiens]
          Length = 351

 Score =  714 bits (1844), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT 60
           MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT
Sbjct: 1   MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT 60

Query: 61  GTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQ 120
           GTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQ
Sbjct: 61  GTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQ 120

Query: 121 LVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGC 180
           LVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGC
Sbjct: 121 LVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGC 180

Query: 181 SRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTV 240
           SRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTV
Sbjct: 181 SRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTV 240

Query: 241 ISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGI 300
           ISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGI
Sbjct: 241 ISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGI 300

Query: 301 LQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL 351
           LQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL
Sbjct: 301 LQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL 351


>gi|226246680 prostaglandin reductase 2 [Homo sapiens]
          Length = 351

 Score =  714 bits (1844), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT 60
           MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT
Sbjct: 1   MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT 60

Query: 61  GTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQ 120
           GTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQ
Sbjct: 61  GTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQ 120

Query: 121 LVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGC 180
           LVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGC
Sbjct: 121 LVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGC 180

Query: 181 SRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTV 240
           SRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTV
Sbjct: 181 SRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTV 240

Query: 241 ISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGI 300
           ISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGI
Sbjct: 241 ISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGI 300

Query: 301 LQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL 351
           LQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL
Sbjct: 301 LQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL 351


>gi|22748929 prostaglandin reductase 2 [Homo sapiens]
          Length = 351

 Score =  714 bits (1844), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT 60
           MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT
Sbjct: 1   MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT 60

Query: 61  GTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQ 120
           GTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQ
Sbjct: 61  GTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQ 120

Query: 121 LVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGC 180
           LVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGC
Sbjct: 121 LVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGC 180

Query: 181 SRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTV 240
           SRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTV
Sbjct: 181 SRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTV 240

Query: 241 ISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGI 300
           ISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGI
Sbjct: 241 ISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGI 300

Query: 301 LQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL 351
           LQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL
Sbjct: 301 LQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL 351


>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score =  203 bits (516), Expect = 2e-52
 Identities = 134/331 (40%), Positives = 183/331 (55%), Gaps = 21/331 (6%)

Query: 16  GNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVD 75
           G P   +F ++   LP  +  G+V +  L+L+VDPYMR         D +   Q+++VV 
Sbjct: 15  GYPTNSDFELKTAELPP-LKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVV- 72

Query: 76  GGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDG-HLSYFLGAIG 134
                   ESK+  L KG  V +    W T  I DG  LEK+  +  D   LS  LG +G
Sbjct: 73  --------ESKNVALPKGTIVLASPG-WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123

Query: 135 MPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCI 194
           MPGLT+  G+ E   +  G  +T++V+ AAGA GSV GQI    GC +VVG  G+ EK  
Sbjct: 124 MPGLTAYFGLLEICGVKGG--ETVMVNAAAGAVGSVVGQIAKLKGC-KVVGAVGSDEKVA 180

Query: 195 LLTSELGFDAAINYKK-DNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILC 253
            L  +LGFD   NYK  +++ E L+++ P G D YFDNVGG  S+TVI QM +   I +C
Sbjct: 181 YL-QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAIC 239

Query: 254 GQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYK-DKFEPGILQLSQWFKEGKL 312
           G IS YN+  P PP   P I   Q+ R    E F+V  ++ D  +  +  L +W  EGK+
Sbjct: 240 GAISTYNRTGPLPPGPPPEIVIYQELR---MEAFVVYRWQGDARQKALKDLLKWVLEGKI 296

Query: 313 KIKETVINGLENMGAAFQSMMTGGNIGKQIV 343
           + KE +I G ENM AAF  M+ G N+GK IV
Sbjct: 297 QYKEYIIEGFENMPAAFMGMLKGDNLGKTIV 327


>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score =  203 bits (516), Expect = 2e-52
 Identities = 134/331 (40%), Positives = 183/331 (55%), Gaps = 21/331 (6%)

Query: 16  GNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVD 75
           G P   +F ++   LP  +  G+V +  L+L+VDPYMR         D +   Q+++VV 
Sbjct: 15  GYPTNSDFELKTAELPP-LKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVV- 72

Query: 76  GGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDG-HLSYFLGAIG 134
                   ESK+  L KG  V +    W T  I DG  LEK+  +  D   LS  LG +G
Sbjct: 73  --------ESKNVALPKGTIVLASPG-WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123

Query: 135 MPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCI 194
           MPGLT+  G+ E   +  G  +T++V+ AAGA GSV GQI    GC +VVG  G+ EK  
Sbjct: 124 MPGLTAYFGLLEICGVKGG--ETVMVNAAAGAVGSVVGQIAKLKGC-KVVGAVGSDEKVA 180

Query: 195 LLTSELGFDAAINYKK-DNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILC 253
            L  +LGFD   NYK  +++ E L+++ P G D YFDNVGG  S+TVI QM +   I +C
Sbjct: 181 YL-QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAIC 239

Query: 254 GQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYK-DKFEPGILQLSQWFKEGKL 312
           G IS YN+  P PP   P I   Q+ R    E F+V  ++ D  +  +  L +W  EGK+
Sbjct: 240 GAISTYNRTGPLPPGPPPEIVIYQELR---MEAFVVYRWQGDARQKALKDLLKWVLEGKI 296

Query: 313 KIKETVINGLENMGAAFQSMMTGGNIGKQIV 343
           + KE +I G ENM AAF  M+ G N+GK IV
Sbjct: 297 QYKEYIIEGFENMPAAFMGMLKGDNLGKTIV 327


>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
          Length = 301

 Score =  166 bits (420), Expect = 3e-41
 Identities = 117/304 (38%), Positives = 163/304 (53%), Gaps = 21/304 (6%)

Query: 16  GNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVD 75
           G P   +F ++   LP  +  G+V +  L+L+VDPYMR         D +   Q+++VV 
Sbjct: 15  GYPTNSDFELKTAELPP-LKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVV- 72

Query: 76  GGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDG-HLSYFLGAIG 134
                   ESK+  L KG  V +    W T  I DG  LEK+  +  D   LS  LG +G
Sbjct: 73  --------ESKNVALPKGTIVLASPG-WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123

Query: 135 MPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCI 194
           MPGLT+  G+ E   +  G  +T++V+ AAGA GSV GQI    GC +VVG  G+ EK  
Sbjct: 124 MPGLTAYFGLLEICGVKGG--ETVMVNAAAGAVGSVVGQIAKLKGC-KVVGAVGSDEKVA 180

Query: 195 LLTSELGFDAAINYKK-DNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILC 253
            L  +LGFD   NYK  +++ E L+++ P G D YFDNVGG  S+TVI QM +   I +C
Sbjct: 181 YL-QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAIC 239

Query: 254 GQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYK-DKFEPGILQLSQWFKEGKL 312
           G IS YN+  P PP   P I   Q+ R    E F+V  ++ D  +  +  L +W  E K 
Sbjct: 240 GAISTYNRTGPLPPGPPPEIVIYQELR---MEAFVVYRWQGDARQKALKDLLKWVLEIKR 296

Query: 313 KIKE 316
           + +E
Sbjct: 297 ENEE 300


>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
           [Homo sapiens]
          Length = 377

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 64/222 (28%), Positives = 106/222 (47%), Gaps = 12/222 (5%)

Query: 137 GLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILL 196
           G T+ I ++E G ++ G  K ++V+ AAG  G  A Q+     C  V+G C + EK   L
Sbjct: 157 GTTAYISLKELGGLSEG--KKVLVTAAAGGTGQFAMQLSKKAKC-HVIGTCSSDEKSAFL 213

Query: 197 TSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILCGQI 256
            S LG D  INYK + V   L++  P GVDV +++VGG + D  +  +     +I+ G I
Sbjct: 214 KS-LGCDRPINYKTEPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFI 272

Query: 257 SQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGILQLSQWFKEGKLKIK- 315
           S Y       P  +  + A   +++ + + F + +Y  K++  +  L +    G L  + 
Sbjct: 273 SGYQTPTGLSPVKAGTLPAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEV 332

Query: 316 -------ETVINGLENMGAAFQSMMTGGNIGKQIVCISEEIS 350
                  E    GLE++  A   M  G N GK +V +   ++
Sbjct: 333 DLGDLSPEGRFTGLESIFRAVNYMYMGKNTGKIVVELPHSVN 374


>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
           sapiens]
          Length = 396

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 38/150 (25%), Positives = 65/150 (43%), Gaps = 16/150 (10%)

Query: 93  GDFVTSFYWPWQTK-----VILDGNSLEKVDPQLVDGHLSY--FLGAIGMPGLTSLIGIQ 145
           GD V +   PW+       V++ GN +      L     +   ++       +  + G+ 
Sbjct: 140 GDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLN 199

Query: 146 EKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAA 205
           +K      + K +++ GA+G  G+ A Q+      + V  +C   +    L  +LG D  
Sbjct: 200 DKNC----TGKRVLILGASGGVGTFAIQVMKAWD-AHVTAVCS--QDASELVRKLGADDV 252

Query: 206 INYKKDNVAEQLRESCPAGVDVYFDNVGGN 235
           I+YK  +V EQL+   P   D   DNVGG+
Sbjct: 253 IDYKSGSVEEQLKSLKP--FDFILDNVGGS 280


>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 35.8 bits (81), Expect = 0.059
 Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 5/124 (4%)

Query: 132 AIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHE 191
           AI    LT+   +   G++ AG +  ++ +G +G  G+ A Q+    G   +V   G+ +
Sbjct: 120 AIPEAWLTAFQLLHLVGNVQAG-DYVLIHAGLSGV-GTAAIQLTRMAGAIPLV-TAGSQK 176

Query: 192 KCILLTSELGFDAAINYKKDNVAE-QLRESCPAGVDVYFDNVGGNISDTVISQMNENSHI 250
           K + +  +LG  A  NYKK++ +E  L+ +  AGV++  D +GG+  +  ++ +  +   
Sbjct: 177 K-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235

Query: 251 ILCG 254
           +L G
Sbjct: 236 VLYG 239


>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 35.8 bits (81), Expect = 0.059
 Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 5/124 (4%)

Query: 132 AIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHE 191
           AI    LT+   +   G++ AG +  ++ +G +G  G+ A Q+    G   +V   G+ +
Sbjct: 120 AIPEAWLTAFQLLHLVGNVQAG-DYVLIHAGLSGV-GTAAIQLTRMAGAIPLV-TAGSQK 176

Query: 192 KCILLTSELGFDAAINYKKDNVAE-QLRESCPAGVDVYFDNVGGNISDTVISQMNENSHI 250
           K + +  +LG  A  NYKK++ +E  L+ +  AGV++  D +GG+  +  ++ +  +   
Sbjct: 177 K-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235

Query: 251 ILCG 254
           +L G
Sbjct: 236 VLYG 239


>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
          Length = 393

 Score = 33.9 bits (76), Expect = 0.22
 Identities = 41/180 (22%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 63  DYITPWQLSQVVDGGGIGIIEESKHTNLTKGD--FVTSFYWPWQTKVILDGNSLEKVDPQ 120
           D + P  ++  ++G G+ I      ++   GD   V +    WQ +V     ++  V   
Sbjct: 101 DRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEEV-----TVPSVQTF 155

Query: 121 LVDGHLSYF-LGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLG 179
           L+   +++    A+ +  +T+ + + + G++  G +  ++V  AAG  G  A Q+   + 
Sbjct: 156 LIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHS--VLVHMAAGGVGMAAVQLCRTVE 213

Query: 180 CSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDT 239
              V G     +   L   E G    I+Y   +  +++++  P GVD+  D +GG  SDT
Sbjct: 214 NVTVFGTASASKHEAL--KENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGG--SDT 269


>gi|37620210 hypothetical protein LOC116228 [Homo sapiens]
          Length = 118

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 9/58 (15%)

Query: 165 GACGSVAGQIGHFLGCSRV-----VGICGTHEKCILLTSELGFDAAINYKKDNVAEQL 217
           G+ GSV    GHFL  SR+     VG+ G     IL+T    F    NY K  + E++
Sbjct: 37  GSLGSVVAGFGHFLFTSRIRRSCDVGVGG----FILVTLGCWFHCRYNYAKQRIQERI 90


>gi|23510356 RIO kinase 1 isoform 1 [Homo sapiens]
          Length = 568

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 10/86 (11%)

Query: 1   MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT 60
           M+   V++ S  GK+  P           L  N+   + + R LYL V  YMR RM +D 
Sbjct: 269 MLRSHVLVMSFIGKDDMPAP---------LLKNVQLSESKARELYLQVIQYMR-RMYQDA 318

Query: 61  GTDYITPWQLSQVVDGGGIGIIEESK 86
              +    + + +  GGG+ II+ S+
Sbjct: 319 RLVHADLSEFNMLYHGGGVYIIDVSQ 344


>gi|23510358 RIO kinase 1 isoform 2 [Homo sapiens]
          Length = 327

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 10/86 (11%)

Query: 1   MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDT 60
           M+   V++ S  GK+  P           L  N+   + + R LYL V  YMR RM +D 
Sbjct: 28  MLRSHVLVMSFIGKDDMPAP---------LLKNVQLSESKARELYLQVIQYMR-RMYQDA 77

Query: 61  GTDYITPWQLSQVVDGGGIGIIEESK 86
              +    + + +  GGG+ II+ S+
Sbjct: 78  RLVHADLSEFNMLYHGGGVYIIDVSQ 103


>gi|31543093 galactosidase, beta 1-like 2 [Homo sapiens]
          Length = 636

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 11/81 (13%)

Query: 225 VDVYFDNVGGNISDTVISQMNENSHIILC---GQISQYNKDVPYPPPLSPAIEAIQKERN 281
           VD+YFD++   +S  V  Q      II      +   YNKD  Y P +  A+E    +R 
Sbjct: 171 VDLYFDHL---MSRVVPLQYKRGGPIIAVQVENEYGSYNKDPAYMPYVKKALE----DRG 223

Query: 282 ITRERFLVLNYKDKFEPGILQ 302
           I  E  L  + KD    GI+Q
Sbjct: 224 IV-ELLLTSDNKDGLSKGIVQ 243


>gi|221554518 cyclin L2 isoform D [Homo sapiens]
          Length = 227

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 19/64 (29%), Positives = 30/64 (46%)

Query: 152 AGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKD 211
           AGS      +GA G+ G+ +G  G  +G     G+  T E C+L   +L F  +++   D
Sbjct: 11  AGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLD 70

Query: 212 NVAE 215
              E
Sbjct: 71  TDTE 74


>gi|221554516 cyclin L2 isoform C [Homo sapiens]
          Length = 236

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 19/64 (29%), Positives = 30/64 (46%)

Query: 152 AGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKD 211
           AGS      +GA G+ G+ +G  G  +G     G+  T E C+L   +L F  +++   D
Sbjct: 11  AGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLD 70

Query: 212 NVAE 215
              E
Sbjct: 71  TDTE 74


>gi|88758578 cyclin L2 isoform B [Homo sapiens]
          Length = 226

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 19/64 (29%), Positives = 30/64 (46%)

Query: 152 AGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKD 211
           AGS      +GA G+ G+ +G  G  +G     G+  T E C+L   +L F  +++   D
Sbjct: 11  AGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLD 70

Query: 212 NVAE 215
              E
Sbjct: 71  TDTE 74


>gi|88758580 cyclin L2 isoform A [Homo sapiens]
          Length = 520

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 19/64 (29%), Positives = 30/64 (46%)

Query: 152 AGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKD 211
           AGS      +GA G+ G+ +G  G  +G     G+  T E C+L   +L F  +++   D
Sbjct: 11  AGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLD 70

Query: 212 NVAE 215
              E
Sbjct: 71  TDTE 74


>gi|49640014 ubiquitin associated and SH3 domain containing, A short
           form [Homo sapiens]
          Length = 623

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 13/37 (35%), Positives = 20/37 (54%)

Query: 270 SPAIEAIQKERNITRERFLVLNYKDKFEPGILQLSQW 306
           SPA+  +Q  + I  E  L    K + EPGI + ++W
Sbjct: 443 SPALRCVQTAKLILEELKLEKKIKIRVEPGIFEWTKW 479


>gi|9507221 ubiquitin associated and SH3 domain containing, A long
           form [Homo sapiens]
          Length = 661

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 13/37 (35%), Positives = 20/37 (54%)

Query: 270 SPAIEAIQKERNITRERFLVLNYKDKFEPGILQLSQW 306
           SPA+  +Q  + I  E  L    K + EPGI + ++W
Sbjct: 481 SPALRCVQTAKLILEELKLEKKIKIRVEPGIFEWTKW 517


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.137    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,384,749
Number of Sequences: 37866
Number of extensions: 574193
Number of successful extensions: 1415
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1376
Number of HSP's gapped (non-prelim): 23
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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